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The Prevalence of Posttraumatic Stress Disorders (PTSD) in Spinal Cord Injury and Traumatic Brain Injury Following Road Traffic Accident: A Systematic Review and Meta-analysis. 道路交通事故后脊髓损伤和创伤性脑损伤中创伤后应激障碍(PTSD)的患病率:系统回顾和荟萃分析。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-30 DOI: 10.1097/NMD.0000000000001835
Reza Aletaha, Amin Abbasi, Zahra Sabahi, Homayoun Sadeghi-Bazargani, Seyed Taher Mousavi, Mina Golestani, Sakineh Hajebrahimi, Amirreza Naseri, Hanieh Salehi-Pourmehr, Alireza Motamedi

Introduction: The prevalence of PTSD in individuals who suffer traumatic brain injury (TBI) or spinal cord injury (SCI) following road traffic accidents (RTAs) has not been comprehensively reviewed.

Methods: A systematic search was conducted in Cochrane, PubMed, Scopus, CINAHL, ProQuest, PsycARTICLES, and PsycINFO, and the meta-analyses were performed by the comprehensive meta-analysis (CMA). JBI checklists were utilized for critical appraisal.

Results: The pooled prevalence of PTSD in TBI and SCI survivors of RTAs was 29.4% (95% CI: 22.7% - 37.3%). The rate of PTSD in adults was 29.3% (95% CI: 23.8% - 35.5%), and it was 30.9% (95% CI: 4.4% - 81.3%) in the children subgroup. Coping styles, previous employment, acute stress disorder, and reduced awareness are some of the reported risk factors. Future longitudinal studies should further investigate the prevalence and predictors of PTSD in RTAs to identify early diagnosis and prevention strategies.

在道路交通事故(rta)后遭受创伤性脑损伤(TBI)或脊髓损伤(SCI)的个体中PTSD的患病率尚未得到全面的审查。方法:系统检索Cochrane、PubMed、Scopus、CINAHL、ProQuest、PsycARTICLES、PsycINFO等数据库,采用综合meta分析(comprehensive meta-analysis, CMA)进行meta分析。JBI检查清单用于关键评估。结果:创伤后应激障碍在rta的TBI和SCI幸存者中的总患病率为29.4% (95% CI: 22.7% - 37.3%)。成人PTSD发生率为29.3% (95% CI: 23.8% - 35.5%),儿童亚组为30.9% (95% CI: 4.4% - 81.3%)。应对方式、以前的工作、急性应激障碍和意识降低是一些报道的风险因素。未来的纵向研究应进一步调查地区创伤后应激障碍的患病率和预测因素,以确定早期诊断和预防策略。
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引用次数: 0
Understanding Intergenerational Transmission of Illicit Opioid Use Risk Based on Parent Drug Abuse History: Testing for Age-Graded Effects. 基于父母药物滥用史了解非法阿片类药物使用风险的代际传递:年龄分级效应测试
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-07-21 DOI: 10.1097/NMD.0000000000001846
Thomas Wojciechowski

Introduction: Prior research indicated intergenerational transmission of substance use behaviors via genetic mechanisms. However, there remain gaps in our understanding of these processes. There is a dearth of research examining parental drug use as a predictor of offspring illicit opioid use among justice-involved youth and age-graded effects.

Methods: The Pathways to Desistance data were analyzed. Mixed effects modeling examined the direct effect of parent drug use history on offspring illicit opioid use risk and tested for moderation by age.

Results: Having a parent with a history of drug use predicted increased offspring's illicit opioid use risk, net of all control covariates. There was no significant interaction with age.

Conclusions: The impact of parent drug use history appears to exert a consistent effect on opioid use risk across the life-course. Justice-involved youth whose parents have a history of drug use should be prioritized for intervention to prevent opioid use.

先前的研究表明,物质使用行为的代际传递是通过遗传机制实现的。然而,我们对这些过程的理解仍然存在差距。在涉及司法的青少年中,父母使用药物作为后代非法使用阿片类药物的预测因素和年龄分级影响的研究缺乏。方法:对抗阻通路数据进行分析。混合效应模型检验了父母药物使用史对后代非法阿片类药物使用风险的直接影响,并测试了年龄的调节作用。结果:父母有药物使用史预测后代非法使用阿片类药物的风险增加,净所有控制协变量。与年龄没有显著的相互作用。结论:父母药物使用史的影响似乎在整个生命过程中对阿片类药物使用风险产生一致的影响。父母有吸毒史的参与司法的青少年应优先进行干预,以防止阿片类药物的使用。
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引用次数: 0
Co-Occurrence of Depression, Anxiety, and Burnout: A Cross-Sectional Network Analysis. 抑郁、焦虑和倦怠共现:一个横断面网络分析。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-08-12 DOI: 10.1097/NMD.0000000000001845
Qi-Qi Ge, Ji-Feng Feng, Yan-Jun Liu, Yi-Lin Wu, Ting Hu, Xiao-Na Zhou, Yun-E Liu, Wei Wang

Introduction: Discrepancies persist regarding burnout-depression-anxiety relationships in health care workers (HCWs), hindering interventions. This cross-sectional study developed a symptom-level network model to clarify their interconnections.

Methods: Nine hundred ninety-two HCWs completed online surveys assessing depression, anxiety, and burnout symptoms. A network model was constructed using bridge expected influence (BEI) to identify central symptoms and network comparisons to evaluate work-related stress impacts.

Results: The analysis identified "psychomotor problems" (BEI=0.96, 95% CI [0.78, 1.11]), "irritability" (BEI=0.85, 95% CI [0.68, 1.02]), and "collapse" (BEI=0.78, 95% CI [0.58, 0.99]) as central symptoms. Network comparison revealed no significant differences in the structure of symptom networks among varying levels of stress (global strength in high-stress condition: 13.50; moderate-stress condition: 13.06; S =0.44, p =.17).

Conclusions: Preliminary evidence indicates interventions targeting "psychomotor problems," "irritability," and "collapse" can be applied across varying stress levels. Targeting these symptoms might disrupt cross-diagnostic activation pathways to mitigate comorbidities in HCWs.

在卫生保健工作者(HCWs)中,关于倦怠-抑郁-焦虑关系的差异持续存在,阻碍了干预。本横断面研究建立了一个症状水平的网络模型来阐明它们之间的相互联系。方法:992名医护人员完成了评估抑郁、焦虑和倦怠症状的在线调查。本研究采用桥式期望影响(BEI)来识别中心症状,并利用网络比较来评估工作压力的影响。结果:分析确定“精神运动问题”(BEI=0.96, 95% CI[0.78, 1.11])、“易怒”(BEI=0.85, 95% CI[0.68, 1.02])和“崩溃”(BEI=0.78, 95% CI[0.58, 0.99])为中心症状。网络比较显示,不同应激水平的症状网络结构无显著差异(高应激条件下的整体强度:13.50;中等应力状态:13.06;S = 0.44, p =。)。结论:初步证据表明,针对“精神运动问题”、“易怒”和“崩溃”的干预措施可以适用于不同的压力水平。针对这些症状可能会破坏交叉诊断激活途径,以减轻HCWs的合并症。
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引用次数: 0
Prodromal Symptoms of Schizophrenia, Childhood Maltreatment, Attachment Insecurity, and Alexithymia: A Correlation Network Approach. 精神分裂症前驱症状、儿童虐待、依恋不安全感和述情障碍:一个相关网络方法。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-08-12 DOI: 10.1097/NMD.0000000000001844
Lucia Sideli, Andrea Fontana, Lucrezia Trani, Gaia Cuzzocrea, Marta Mascanzoni, Riccardo Pecora, Anna Chiara Franquillo, Arianna Cantiano, Diletta D'Offizi, Patrizia Brogna, Chiara Caprì, Isabella Panaccione, Gianluigi di Cesare, Giuseppe Ducci, Vincenzo Caretti

Introduction: Prodromal psychotic symptoms have been increasingly linked to childhood maltreatment, attachment insecurity, and alexithymia, particularly difficulties in identifying and expressing emotions.

Method and results: This study employed correlation network analysis to examine the interplay among early adversities, alexithymia, and prodromal psychosis symptoms in 93 adolescents (64% female) attending their first visit to a youth mental health center. Of these, 39% met the criteria for prodromal symptoms of psychosis. The network identified difficulty identifying feelings, emotional abuse, and physical neglect as the most central nodes. Difficulty identifying feelings and general psychopathology emerged as key bridge nodes connecting symptom domains.

Conclusions: Findings suggest that difficulties in emotion regulation and general psychological distress may mediate the pathway from child maltreatment to prodromal psychotic symptoms. These dimensions represent important targets for early intervention in at-risk adolescents.

前驱精神病症状越来越多地与童年虐待、依恋不安全感和述情障碍,特别是识别和表达情绪的困难联系在一起。方法与结果:本研究采用相关网络分析方法,对首次到青少年心理健康中心就诊的93名青少年(女性占64%)进行了早期逆境、述情障碍和前驱精神病症状之间的相互作用研究。其中39%符合精神病前驱症状的标准。该网络发现,难以识别情感、情感虐待和身体忽视是最重要的节点。难以识别的感觉和一般的精神病理出现了连接症状域的关键桥梁节点。结论:研究结果提示情绪调节困难和一般心理困扰可能介导儿童虐待到精神病症状前驱的通路。这些方面是高危青少年早期干预的重要目标。
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引用次数: 0
Evaluation of Social Media Use in Bipolar Disorder in Terms of Past Suicide Attempts and Its Impact on Quality of Life. 从过去自杀企图的角度评估双相情感障碍患者的社交媒体使用及其对生活质量的影响。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-08-12 DOI: 10.1097/NMD.0000000000001847
Ece Buyuksandalyaci Tunc, Tulay Sati Kirkan

Abstract: This study aims to compare the quality of life and past suicide attempts of bipolar disorder (BD) patients with social media (SM) use. The study included 100 BD patients. All participants underwent assessments using the Functional Assessment Short Test (FAST), Social Media Use Disorder Scale (SMDS), and 36-Item Short Form Survey (SF-36). Past suicidal behaviors were also noted. FAST scores in the SM group were significantly ( p <0.05) lower than those not using SM. The SF-36 scores in the group using SM were significantly higher ( p <0.05) than those not using SM. Previous suicide attempts did not affect SM usage. When considering the more frequent utilization of SM among patients with a history of suicide attempts, encouraging these patients to follow productive content in SM could be a way to reintegrate them into life.

摘要:本研究旨在比较使用社交媒体(SM)的双相情感障碍(BD)患者的生活质量和过去的自杀企图。该研究包括100名双相障碍患者。所有参与者都接受了功能评估简短测试(FAST)、社交媒体使用障碍量表(SMDS)和36项简短表格调查(SF-36)的评估。过去的自杀行为也被记录下来。SM组的FAST评分显著高于对照组(p
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引用次数: 0
Prevalence of Suicidal Thoughts and Behaviors and Its Disclosure in the German General Population. 德国普通人群自杀念头和行为的流行程度及其披露。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-08-12 DOI: 10.1097/NMD.0000000000001848
Lena Spangenberg, Juliane Brüdern, Heide Glaesmer

Introduction: The paper presents reference values for the Suicidal Behaviors Questionnaire-Revised (SBQ-R) and population-based lifetime and 12-month prevalences on suicide related thoughts and behaviors (STBs).

Methods: A representative sample of the general German population was assessed (n=2.513).

Results: Mean SBQ-R score was 3.8. Lifetime prevalence of STBs was 15.5% (n=388), with higher rates found in women and in middle-aged adults. Lifetime STBs were disclosed by 5.7% (n=142) of respondents. 12-month prevalence was 5.1%, with women showing higher rates.

Conclusions: The results enable other researchers to compare their data to representative reference values on a widely used measure for STBs. Future studies might address the problem of low disclosure of STBs as well as the impact of methodological aspects, such as wording, on prevalence rates.

前言:本研究提供了自杀行为问卷修订版(SBQ-R)和基于人群的自杀相关思想和行为(STBs)终生患病率和12个月患病率的参考价值。方法:选取德国普通人群的代表性样本进行评估(n=2.513)。结果:平均SBQ-R评分为3.8分。性传播感染的终生患病率为15.5% (n=388),女性和中年人的患病率较高。5.7% (n=142)的受访者披露了终身性传播感染。12个月患病率为5.1%,女性患病率更高。结论:该结果使其他研究人员能够将他们的数据与广泛使用的stb测量的代表性参考值进行比较。今后的研究可能会处理性传染疾病披露率低的问题,以及诸如措辞等方法方面对流行率的影响。
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引用次数: 0
Trauma Type and Posttraumatic Stress Symptoms in Youth: The Mediating Role of Intolerance of Uncertainty. 青年创伤类型与创伤后应激症状:不确定性不耐受的中介作用。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-08-01 Epub Date: 2025-08-12 DOI: 10.1097/NMD.0000000000001837
Alexandra Doehrmann, Sophia A Bibb, Kayla A Kreutzer, Stephanie M Gorka

Objective: Early-life trauma is associated with posttraumatic stress symptoms (PTSS) in young adulthood; although factors that contribute to PTSS are unclear, one factor may be Intolerance of uncertainty. In adults, trauma exposure may enhance IU and in turn, contribute to PTSS. Few studies have explored these associations in youth or considered the role of trauma type. This study examined these associations in a cohort of youth (ages 18-19) with varying trauma histories.

Methods: Participants (N = 129) completed validated measures of lifetime trauma exposure, IU, and PTSS. The unique effects of commonly endorsed trauma types were examined: sexual violence, physical abuse, emotional abuse, witnessing domestic violence, and caregiver separation.

Results: Sexual violence victimization was uniquely associated with higher IU, and IU mediated the relationship between sexual violence victimization and PTSS.

Conclusions: Heightened IU may be one pathway through which exposure to sexual violence increases risk for psychopathology.

目的:早期生活创伤与青年期创伤后应激症状(PTSS)相关;虽然导致ptsd的因素尚不清楚,但其中一个因素可能是对不确定性的不耐受。在成人中,创伤暴露可能会增强IU,进而导致ptsd。很少有研究探讨这些联系在青年或考虑创伤类型的作用。本研究在一组有不同创伤史的青年(18-19岁)中研究了这些关联。方法:参与者(N = 129)完成了终身创伤暴露、IU和创伤后应激障碍的有效测量。研究了常见的创伤类型的独特影响:性暴力、身体虐待、情感虐待、目睹家庭暴力和照顾者分离。结果:性暴力受害与高IU相关,IU在性暴力受害与创伤后应激障碍之间起中介作用。结论:高IU可能是暴露于性暴力增加精神病理风险的途径之一。
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引用次数: 0
Psychiatric Comorbidities in Fibromyalgia: A Comparison With Chronic Conditions and Healthy Controls. 纤维肌痛的精神合并症:与慢性疾病和健康对照的比较
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-08-01 Epub Date: 2025-07-16 DOI: 10.1097/NMD.0000000000001836
Chen Avni, Maya Morr, Dana Sinai, Paz Toren

Introduction: Fibromyalgia is characterized by chronic widespread pain and psychiatric comorbidities, but robust comparative data remain limited.

Methods: This retrospective cohort study compared psychiatric diagnoses and medication use among matched groups with fibromyalgia, chronic pain, chronic fatigue syndrome, rheumatoid arthritis, and healthy controls (total N=5,040), using data from a large national health care provider.

Results: Psychiatric disorders were most prevalent in fibromyalgia, followed by chronic pain, chronic fatigue syndrome, rheumatoid arthritis, and healthy controls. In fibromyalgia patients, anxiety (55.1%) and depression (48.7%) were predominant, accompanied by extensive medication use. Notably, fibromyalgia showed exceptionally high relative risks for Cluster B personality disorders (RR=34), personality disorders overall (RR=24), and PTSD (RR=22.75).

Conclusions: Fibromyalgia patients experience significantly elevated psychiatric comorbidities compared with other chronic conditions. Comprehensive and integrated multidisciplinary care strategies are necessary to address the distinct psychiatric burden associated with fibromyalgia. This study extends prior work by directly comparing fibromyalgia to other chronic conditions and identifying distinct psychiatric risk patterns in a culturally diverse national cohort.

纤维肌痛的特点是慢性广泛疼痛和精神合并症,但可靠的比较数据仍然有限。方法:这项回顾性队列研究比较了纤维肌痛、慢性疼痛、慢性疲劳综合征、类风湿关节炎和健康对照患者的精神病诊断和药物使用情况(总N= 5040),数据来自一家大型国家卫生保健机构。结果:精神疾病在纤维肌痛患者中最为普遍,其次是慢性疼痛、慢性疲劳综合征、类风湿关节炎和健康对照组。纤维肌痛患者以焦虑(55.1%)和抑郁(48.7%)为主,并伴有广泛的药物使用。值得注意的是,纤维肌痛显示出B类人格障碍(RR=34)、整体人格障碍(RR=24)和创伤后应激障碍(RR=22.75)的异常高的相对风险。结论:与其他慢性疾病相比,纤维肌痛患者的精神合并症明显升高。全面和综合的多学科护理策略是必要的,以解决与纤维肌痛相关的独特精神负担。本研究通过直接比较纤维肌痛与其他慢性疾病,并在文化多样化的国家队列中确定不同的精神风险模式,扩展了先前的工作。
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引用次数: 0
Exploring Emotional Contagion and Emotional Mimicry in Schizotypy: Uncovering Residual Effects Post Depression Control. 探索精神分裂型的情绪传染和情绪模仿:揭示抑郁控制后的残余效应。
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-08-01 Epub Date: 2025-07-29 DOI: 10.1097/NMD.0000000000001840
Mathilde Parisi, Ludovic Marin, Tifenn Fauviaux, Lina Sayem, Marie-Pierre Soulé, Carla Leone, Stéphane Raffard

Objective: Schizotypy, a trait vulnerability for psychotic disorders, is linked to social functioning deficits. Emotional contagion (the transfer of emotion between individuals) and emotional mimicry (the imitation of emotional expression) are key to social interactions but remain understudied in schizophrenia-spectrum disorders. This study examined schizotypy's influence on these processes while controlling for depression.

Methods: Sixty healthy participants completed a questionnaire assessing emotional contagion, emotional mimicry, schizotypy (SPQ-B), and depression (BDI-II). Emotional contagion was measured through self-reported emotions before and after emotional videos. Emotional mimicry was assessed by analyzing webcam-recorded facial expressions using OpenFace.

Results: Higher schizotypy correlated with increased sadness contagion and reduced joy contagion, though effects were nonsignificant when controlling for depression. Higher schizotypy was linked to decreased sadness mimicry.

Conclusions: Findings highlight the role of emotional processes in schizotypy and schizophrenia, emphasizing their potential impact on social interactions.

目的:精神分裂型是精神障碍的一种特征易感性,与社会功能缺陷有关。情绪传染(个体之间的情绪转移)和情绪模仿(情绪表达的模仿)是社会互动的关键,但在精神分裂症谱系障碍中仍未得到充分研究。这项研究在控制抑郁的情况下检验了精神分裂对这些过程的影响。方法:60名健康参与者完成了情绪感染、情绪模仿、精神分裂(SPQ-B)和抑郁(BDI-II)的问卷调查。情绪传染是通过情绪视频前后自我报告的情绪来衡量的。通过使用OpenFace分析网络摄像头记录的面部表情来评估情绪模仿。结果:较高的分裂型与增加的悲伤传染和减少的快乐传染相关,尽管在控制抑郁时影响不显著。精神分裂程度越高,悲伤模仿程度越低。结论:研究结果强调了情绪过程在精神分裂型和精神分裂症中的作用,强调了它们对社会互动的潜在影响。
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引用次数: 0
How is Burnout Self-identified? 倦怠是如何自我识别的?
IF 1.3 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-08-01 Epub Date: 2025-07-29 DOI: 10.1097/NMD.0000000000001843
Nicole Russo, Andrew Camara, Gordon Parker

Introduction/trial design: We report a cross-sectional study pursuing the sources of information that lead individuals to judge that they had burnout.

Methods: An online survey in 2023 involved 903 Australians who judged they had burnout. Participants nominated their key symptoms, consulted sources, and completed the Sydney Burnout Measure (SBM) and the Burnout Assessment Tool (BAT).

Results: Participants' own knowledge and awareness were the most nominated sources, while only 29.5% of sufferers received a diagnosis from a health professional. Those who consulted a health professional returned higher SBM and BAT scores and rates of physical symptoms, sleep changes and loss of executive function, suggesting greater syndrome severity. Participants nominated more symptoms than the three currently thought to define a burnout syndrome, but none were universally nominated.

Conclusions: Study findings challenge the dominant triadic model of burnout and assist in understanding why a clinical diagnosis of burnout is complex.

引言/试验设计:我们报告了一项横断面研究,旨在寻找导致个体判断自己倦怠的信息来源。方法:2023年的一项在线调查涉及903名澳大利亚人,他们认为自己已经精疲力竭。参与者提名他们的主要症状,咨询来源,并完成悉尼倦怠量表(SBM)和倦怠评估工具(BAT)。结果:参与者自己的知识和意识是最被提名的来源,而只有29.5%的患者从健康专业人员那里得到了诊断。那些咨询过健康专家的人,他们的SBM和BAT得分更高,身体症状、睡眠改变和执行功能丧失的比例也更高,这表明综合症的严重程度更高。参与者提出的症状比目前认为定义倦怠综合征的三种症状更多,但没有一种得到普遍提名。结论:研究结果挑战了主导的倦怠三合一模型,并有助于理解为什么倦怠的临床诊断是复杂的。
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引用次数: 0
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Journal of Nervous and Mental Disease
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