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Recommended natural products in Alzheimer's disease based on traditional Persian medicine 推荐的天然产品在阿尔茨海默氏症基于传统波斯医学
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.17
Amir Hossein Jamshidi, F. Eghbalian, S. Mahroozade, Hoorieh Mohammadi kenari, A. Ghobadi, B. Yousefsani
Background: Alzheimer's disease is the most common cause of dementia, especially in elderlies. Its exact pathogenesis is not yet known and existing therapies do not have enough efficacy. Therefore, the use of complementary therapies such as traditional Persian medicine for improving memory function is increasing. Objective: The aim of this study is evaluating recommended natural products in important traditional Persian medicine textbooks. Methods: For this purpose, keywords such as "Nesyan" (ie: oblivion, amnesia), "Hafezeh" (ie: memory), "Zekr" (ie: mention) and "Faramoushi" (ie: forgetfulness( were used to search in recommended prescription in important traditional Persian medicine textbooks. Then, the most repeated plants were extracted from the prescription and evaluated for their pharmacological properties recently published articles cited in the scientific databases such as Google Scholar, PubMed, Medline, and Scopus. Results: 262 natural products were in 96 evaluated prescription, 40 natural products were more
背景:阿尔茨海默病是痴呆症最常见的原因,尤其是在老年人中。其确切的发病机制尚不清楚,现有的治疗方法也不够有效。因此,使用补充疗法,如传统的波斯医学来改善记忆功能正在增加。目的:对波斯传统医学重要教科书中推荐的天然产物进行评价。方法:采用“Nesyan”(遗忘、健忘症)、“Hafezeh”(记忆)、“Zekr”(提及)、“Faramoushi”(健忘)等关键词对重要波斯传统医学教科书中的推荐处方进行检索。然后,从处方中提取重复次数最多的植物,并对其药理特性进行评估,这些药理特性最近发表在谷歌Scholar、PubMed、Medline和Scopus等科学数据库中。结果:96份评价处方中含有262种天然产物,40种以上天然产物
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引用次数: 8
Molecular docking studies of some flavone analogues as α-Glucosidase inhibitors 几种黄酮类似物作为α-葡萄糖苷酶抑制剂的分子对接研究
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.55
M. Sadeghi, M. Zarei
investigate in of the This a The of the and α-glucosidase of the to
α-葡萄糖苷酶的研究
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引用次数: 10
Preparation and evaluation of chitosan-zein film containing free and encapsulated ethanol extract of kak kosh biabani Pulicaria gnaphalodes (Vent.) Boiss. 壳聚糖-玉米醇溶蛋白膜的制备和评价。
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.223
Abbas Mahdizadeh, S. Shahidi, N. Shariatifar, M. Shiran, A. G. Saraei
Abbreviations: FTIR, Fourier-transform infrared spectroscopy; WVP, Water vapor permeability; EOs, Essential Oils; DPPH, 2,2-diphenyl-1-picrylhydrazyl SEM, Scanning Electron Microscope; TS, Tensile strength; ETB, Elongation at break Background: Today, the tendency to use biodegradable biopolymers as one of the appropriate technologies to prevent food oxidation has received much attention. Objective: The aim of the present study was to produce a new biodegradable films containing free ethanolic extracts and nanocapsules of kak kosh biabani ( Pulicaria gnaphalodes (Vent.) Boiss.),
缩写:FTIR、傅立叶变换红外光谱;WVP,水蒸气渗透率;EOs,精油;DPPH,2,2-二苯基-1-苦基肼SEM,扫描电子显微镜;TS,抗拉强度;ETB,断裂伸长率背景:如今,使用可生物降解的生物聚合物作为防止食品氧化的适当技术之一的趋势受到了广泛关注。目的:本研究的目的是制备一种新的可生物降解膜,该膜含有角鲨的游离乙醇提取物和纳米胶囊(Pulicaria gnaphalodes(Vent.)Boiss.),
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引用次数: 2
A study on chlorophyll, total carotenoid and beta-carotene contents in carrot and the effect of climate on them 胡萝卜中叶绿素、类胡萝卜素和β-胡萝卜素含量及气候影响的研究
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.254
A. Ebadollahinatanzi, G. Arabrahmatipour
Background: Carotenoids are pigments with important physiological effects in the human body that are involved in strengthening the immune system and reducing the risk of many diseases, including cancer. Objective: With regard to the importance of these substances and the high content of them in carrots ( Daucus carota L.), and in order to identify the most suitable geographical area for obtaining the products with the highest levels of these compounds, the present study was carried out. Methods: Samples were collected and investigated from six major carrot cultivation regions, located in Khuzestan and Isfahan provinces. The effects of climate changes on the amount of these substances were also studied. The extracts were prepared from the samples and the experiments were performed by spectrophotometric method at 663, 645, 480 and 436 nm wavelength, repectively. Results: The highest mean of total chlorophyll content
背景:类胡萝卜素是一种在人体内具有重要生理作用的色素,与增强免疫系统和降低包括癌症在内的许多疾病的风险有关。目的:考虑到这些物质在胡萝卜中的重要性和高含量,为了确定获得这些化合物含量最高的产品的最合适的地理区域,进行了本研究。方法:从胡齐斯坦省和伊斯法罕省的六个主要胡萝卜种植区采集样本并进行调查。还研究了气候变化对这些物质数量的影响。从样品中制备提取物,并分别在663、645、480和436nm波长下用分光光度法进行实验。结果:总叶绿素含量平均值最高
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引用次数: 0
Effect of shilajit on the levels of pro-inflammatory and anti inflammatory cytokines in ulcerative colitis induced by acetic acid in male rats 石鸡吉对醋酸致溃疡性结肠炎雄性大鼠促炎和抗炎细胞因子水平的影响
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.78
Fatemeh Alimahdi, N. Shahrokhi, M. Hadad, Gholamerza Asadikaram, M. Abolhasani
Background: The levels of IL-13, IL-4, IL-1B, TNF-α and IL-10 alter in the colon of people with ulcerative colitis. previous studies, it was found that shilajit (asphaltum) was effective in the improvement of ulcerative colitis.we guessed that the shilajit has been able to improve the ulcerative colitis by affecting the amount of cytokines. Objective: The aim of the present study was to investigate the effects of shilajit on IL-13, IL-4, IL-1B, TNF-α and IL-10 in ulcerative colitis. Methods: In this experimental study, 49 white 7 groups colitis, Gavage shilajit, colitis Results: The Gavage shilajit group increased IL-10, IL-4and IL-1β, TNF-α compared to Gavage vehicle group. Shilajit able to close the levels of IL-4, IL-13, IL-10, TNF-α to normal values the sham group. Conclusion: Considering that the of intestinal the of rat the shilajit lower than it can be shown that shilajit has been able to more reduce more suitable change in
背景:溃疡性结肠炎患者结肠中IL-13、IL-4、IL-1B、TNF-α和IL-10水平发生改变。既往研究发现,shilajit(沥青)对溃疡性结肠炎有改善作用。我们猜测shilajit能够通过影响细胞因子的数量来改善溃疡性结肠炎。目的:探讨希拉吉特对溃疡性结肠炎患者IL-13、IL-4、IL-1B、TNF-α、IL-10的影响。方法:在本实验研究中,49白7组结肠炎患者,灌胃希拉吉,结肠炎结果:与灌胃药组相比,灌胃希拉吉组IL-10、il -4、IL-1β、TNF-α升高。假手术组IL-4、IL-13、IL-10、TNF-α水平降至正常水平。结论:考虑到大鼠的肠道代谢水平低于它,可以表明它已经能够更低更合适的改变
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引用次数: 0
Influence of CeO2-Nanoparticles on morpho-physiological tritas and tanshinone contents of roots in Salvia miltiorrihiza Bunge upon foliar and soil application methods 纳米ceo2对丹参草根系形态生理指标和丹参酮含量的影响及叶面和土壤施用方式
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.168
Simin Paryan, M. Ghorbanpour, J. Hadian
Background: Cerium oxide nanoparticles (CeO 2 NPs) may differentially affect physiological and metabolic processes of plants depends on plant species, culture conditions, concentrations and application methods. Objective: Evalaution of the effects of different concentrations of CeO 2 NPs through two different methods at two growth stages on morpho-physiological and phytochemicqal characteristics of red sage ( Salvia miltiorrhiza Bunge). Methods: In this study CeO 2 NPs (0, 250, 500, 1000 mg/l) was applied at two growth stages (vegetative and reproductive) via foliar and soil application in a factorial experiment based on completely randomized design with three replications. Results: Maximum dry weight of aerial parts was obsrved in 250 mg/l CeO 2 NPs foliar application treatment at reproductive stage. Chlorophyll a content was peaked at 250 mg/l CeO 2 NPs soil applied treatment at reproductive stage. Furthermore, the highest content of total phenol, flavonoid, and antioxidant acitivity were obtained in leaf extract of plants foliar treated with 500 mg/l CeO 2 NPs at reproductive stage. The highest root rosmarinic acid and tanshinon content was achived at soil applied CeO 2 NPs of 500 mg/l at reproductive stage, which increased 58.7 and 24.6% compared to the respective control, respectively. Conclusion: According to the obtained results in this study, CeO 2 NPs at 250 and 500 mg/l through foliar application at reproductive stage showed strong effect on improvement of morpho-physiological and phytochemical characteristics in S. miltiorrhiza .
背景:氧化铈纳米颗粒(CeO2 NPs)可能对植物的生理和代谢过程产生不同的影响,这取决于植物种类、培养条件、浓度和施用方法。目的:探讨不同浓度的CeO2 NPs在两个生长阶段通过两种不同的方法对丹参形态、生理和植物化学特性的影响。方法:在本研究中,在完全随机设计的析因实验中,通过叶面和土壤施用CeO2 NPs(0,250,500,1000mg/l),在两个生长阶段(营养期和生殖期)施用三次。结果:生殖期叶面施用CeO2 NPs 2 5 0mg/l处理,地上部分干重最高。叶绿素a含量在2 5 0mg/l CeO2 NPs土壤处理生殖期达到峰值。此外,在生殖期,用500mg/l CeO2 NPs处理的植物叶片提取物中总酚、类黄酮和抗氧化活性含量最高。生殖期施用CeO2 NPs 500mg/l时,根中迷迭香酸和丹参酮含量最高,分别比对照提高58.7%和24.6%。结论:根据本研究结果,生殖期叶面施用2 5 0和5 0 0mg/l的CeO2 NPs对丹参的形态生理和植物化学特性有很强的改善作用。
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引用次数: 2
Hypoglycemic effect of Polygonatum orientale Desf. rhizome extract on diabetes induced by streptozotocin in rat model 黄精的降糖作用。根茎提取物对链脲佐菌素致糖尿病大鼠模型的影响
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.92
Faramarz Azari, M. Vazirian, M. Ardekani, M. Sharifzadeh, Nargess Sadati Lamardi
Background : Polygonatum orientale , an herbaceous and perennial plant from family Asparagaceae, is native to the forests of northern Iran. The hypoglycemic effects of other species of the Polygonatum have been proven. Objective: The aim of this study was to evaluate the hypoglycemic effect of P. orientale rhizome extract and its effects on the
背景:黄精是天门冬科的一种多年生草本植物,原产于伊朗北部的森林。其它种类黄精的降糖作用已被证实。目的:研究东方红根茎提取物的降血糖作用及其对人体的影响
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引用次数: 0
Phytochemical investigation of methanolic extract of Zataria multiflora Boiss. 多花Zataria multiflora Boiss甲醇提取物的植物化学研究。
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.239
E. Nazaryanpour, S. Ebrahimi
Background: Zataria multiflora Boiss. (Lamiaceae) has been found in Iran, Afghanistan, and Pakistan. Z. multiflora called ‘Avishane Shirazi’ in Persian is used as a seasoned in many foods in Iran. The literature survey demonstrated that Z. multiflora has immunostimulant, pain-relieving, antinociceptive, anti-inflammatory, antioxidant, antibacterial, antiviral, antiparasitic, antifungal effects and also widely used in traditional medicine for analgesia, diarrhea, infectious diseases, and gastrointestinal problems. Objective: The subject of this study is performing phytochemical constituents of methanolic extract of Z. multiflora . Methods: The application of various chromatographic techniques such as normal and reverse C18 chromatography let to isolation, purification and identification of several flavonoids . Results: In this investigation, the fractionation of methanol extract of the aerial parts of Z. multiflora led to the isolation and purification of three known flavonoid glycosides namely Luteolin 7-O-glucopyranoside, Apigenin 7-O-rutinoside and Luteolin 7-O-rutinoside whose structures were determined by 1D and 2D-NMR spectroscopic studies, in particular, homo-COSY and hetero (HSQC and HMBC) . Conclusion: The results show a methanolic extract of Z. multiflora is a rich source of flavonoids and triterpenoids.
背景:多花Zataria。(Lamiaceae)已在伊朗、阿富汗和巴基斯坦发现。在伊朗的许多食物中都使用了一种叫做“Avishane Shirazi”的多花Z。文献调查表明,多花Z.multiflora具有免疫刺激、止痛、镇痛、抗炎、抗氧化、抗菌、抗病毒、抗寄生虫、抗真菌等作用,还广泛应用于镇痛、腹泻、传染病和胃肠道问题的传统药物中。目的:对多花紫草甲醇提取物的植物化学成分进行研究。方法:采用正、反相C18色谱等多种色谱技术对几种黄酮类化合物进行分离、纯化和鉴定。结果:通过对多花曲柳地上部分甲醇提取物的分级分离,分离纯化了三种已知的黄酮苷,即木犀草素7-O-吡喃葡糖苷、芹菜素7-O-芸香糖苷和木犀草苷7-O-芸香糖苷,通过1D和2D-NMR光谱研究确定了它们的结构,特别是同源COSY和异源(HSQC和HMBC)。结论:多花泽兰甲醇提取物富含黄酮类化合物和三萜类化合物。
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引用次数: 2
The effect of turmeric and curcumin on neuropathic pain behavioral response of CCI model in rats 姜黄和姜黄素对CCI模型大鼠神经性疼痛行为反应的影响
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.141
H. Safakhah, A. Rashidy-Pour, F. Mohammadzadeh, Abbas Ali Vafaei
Abbreviations: CCI, Chronic Constriction Injury; DNA, Deoxyribonucleic Acid; TNF-α, Tumor necrosis factor alpha; NO, Nitric Oxide; NADH, Nicotinamide Adenine Dinucleotide Hydrogen; LDH, Lactate dehydrogenase; Background: Neuritis is one of the causes of neuropathic pains. It is proved that turmeric and curcumin have anti-neuritis effect that may be reduce of neuropathic pain. Objective: In this study, effects of turmeric and curcumin have been evaluated on behavioral response resulted from chronic constriction injury (CCI) in rat. Methods: In this experimental study Wistar male rat (200-250 gr) were used. For create of CCI, Bennet and Xie (1988) method has been used. 2 weeks after neuritis occurrence, turmeric 60 mg/kg and curcumin 30 and 60 mg/kg injection have been begun and continued until 26 th day as
缩写:CCI,慢性缩窄性损伤;脱氧核糖核酸;TNF-α、肿瘤坏死因子α;NO,一氧化氮;烟酰胺腺嘌呤二核苷酸氢;LDH、乳酸脱氢酶;背景:神经炎是引起神经性疼痛的原因之一。事实证明,姜黄和姜黄素具有抗神经炎的作用,可以减轻神经性疼痛。目的:研究姜黄和姜黄素对大鼠慢性收缩性损伤(CCI)行为反应的影响。方法:本实验采用Wistar雄性大鼠(200-250gr)。对于CCI的创建,采用了Bennet和Xie(1988)的方法。神经炎发生2周后,开始注射姜黄60mg/kg和姜黄素30和60mg/kg,并持续到第26天
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引用次数: 0
Ethnobotanical study of some medicinal plants of Abhar county, Zanjan province 赞詹省阿哈尔县部分药用植物的民族植物学研究
Q3 Medicine Pub Date : 2020-09-01 DOI: 10.29252/jmp.19.75.30
M. Vafadar, Z. Toghranegar
Background: Ethnobotany investigates the traditional and local application of plants in different regions by locals and different cultures. It aims at describing the relationships between cultures and plants, focusing on their applications. Local people and the elderly in each region have a lot of information about the uses of plants. Objective: The purpose of this study was to introduce the most important medicinal plants species in Abhar County and their applications in traditional therapies. Methods: After stydying the area, interviews with native connoisseurs, the medicinal plants of Abhar County were collected during 2015 2016 and by their scientific identification, the names in Persian, Local as well as the organs used, their medicinal properties, and usage were determined. Results: The findings of this study revealed the presence of 71 medicinal plants species belonging to 29 families. The families of Asteraceae, Fabaceae, and Lamiaceae with 11, 10, and 8 species, respectively, are the most important ones in the study area. The most important applications of them in Abhar County are for gastrointestinal disorders (54/93%). They are mostly used in brewed and boiled (76/06%), or extracted form (38/03%). Conclusion: Presence of 71 species of medicinal plants in Abhar County with their various uses by the local people in the treatment
背景:Ethnobotany调查了当地人和不同文化在不同地区对植物的传统和当地应用。它旨在描述文化和植物之间的关系,重点是它们的应用。每个地区的当地人和老年人都有很多关于植物用途的信息。目的:介绍阿布哈尔县最重要的药用植物种类及其在传统疗法中的应用。方法:在封锁该地区后,采访当地鉴赏家,在2015年至2016年期间收集阿布哈尔县的药用植物,并通过科学鉴定,确定其波斯语、当地语名称以及所用器官、药用特性和用途。结果:本研究揭示了29科71种药用植物的存在。菊科、菊科和Lamiaceae的科分别有11种、10种和8种,是研究区内最重要的科。在阿布哈尔县,它们最重要的应用是治疗胃肠道疾病(54/93%)。它们主要用于酿造和煮沸(76/06%)或提取形式(38/03%)。结论:察哈尔县有71种药用植物,当地人民对其治疗有多种用途
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引用次数: 2
期刊
Journal of Medicinal Plants
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