Cancer is one of the dreaded diseases of 20 century responsible for causing most fatalities and spreading further with increasing incidence in 21 century. Ayurveda an ancient science provides many useful remedies for these types of advanced diseases. Upavishas narrated in Agadtantra contribute for many fruitful therapeutic formulations. Snuhi (Euphorbia neriifolia Linn.) is one among these upavishas is knocking out as an effective Anticancer agent. Traditionally it is mainly used in Kushtha, Udara, Shotha, Pandu, Gulma, Dushivisha, Visha chikitsa. Various In Vitro & In Vivo studies has been conducted to evaluate the anticancer activity of Upavisha Snuhi (Euphorbia neriifolia Linn.) in the form of its extracts. In this study a special emphasis is on gathering details of Upavisha Snuhi from available classical text and assemble data related to the In Vivo and In Vitro Anticancer activity of Upavisha Snuhi.
{"title":"ANTICANCER ACTIVITY OF UPAVISHA SNUHI: A COMPREHENSIVE UPDATE","authors":"Asolkar Geeta Govindrao, Nikam Ashwin Vithalrao, Pawade Uday Venkatrao, Anjankar Meghsham Pramodrao","doi":"10.7897/2277-4572.096190","DOIUrl":"https://doi.org/10.7897/2277-4572.096190","url":null,"abstract":"Cancer is one of the dreaded diseases of 20 century responsible for causing most fatalities and spreading further with increasing incidence in 21 century. Ayurveda an ancient science provides many useful remedies for these types of advanced diseases. Upavishas narrated in Agadtantra contribute for many fruitful therapeutic formulations. Snuhi (Euphorbia neriifolia Linn.) is one among these upavishas is knocking out as an effective Anticancer agent. Traditionally it is mainly used in Kushtha, Udara, Shotha, Pandu, Gulma, Dushivisha, Visha chikitsa. Various In Vitro & In Vivo studies has been conducted to evaluate the anticancer activity of Upavisha Snuhi (Euphorbia neriifolia Linn.) in the form of its extracts. In this study a special emphasis is on gathering details of Upavisha Snuhi from available classical text and assemble data related to the In Vivo and In Vitro Anticancer activity of Upavisha Snuhi.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"64 1","pages":"162-166"},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75792007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cancer is one amongst the dreadful diseases of present century. The incidence of cancer is increasing worldwide. Every year about 8,00,000 new cancer patients get registered with the national cancer registry program in India. Ayurveda an ancient Indian medicine science describes many useful herbal drugs for such types of advanced diseases. Upavisha the plant poisons of low potency are mentioned in Agadtantra. Arka (Calotropis procera/ Calotropis gigantea) is one among these Upavisha is emerging as an effective anticancer drug. It shows various pharmacological activities such as Anticancer, Antimicrobial, Antiimplantation etc. Different parts of Arka are used to treat cancer. In current scenario number of synthetic anticancer drugs are used to treat cancer. These synthetic anticancer drugs are expensive and shows harmful adverse effects. Upavisha like Arka which is natural derivative may be cost effective & less harmful as Anticancer drug. Anticancer activity of Calotropis procera/Calotropis gigantea is reported in scientific journals. This review summarizes various In Vitro and In Vivo studies of anticancer activity of Upavisha Arka.
{"title":"ANTICANCER ACTIVITY OF UPAVISHA ARKA: AN OVERVIEW","authors":"Chandekar Deepali Boudhadas, Pawade Uday Venkatrao, Nikam Ashwin Vithalrao, Anjankar Meghsham Pramodrao","doi":"10.7897/2277-4572.096193","DOIUrl":"https://doi.org/10.7897/2277-4572.096193","url":null,"abstract":"Cancer is one amongst the dreadful diseases of present century. The incidence of cancer is increasing worldwide. Every year about 8,00,000 new cancer patients get registered with the national cancer registry program in India. Ayurveda an ancient Indian medicine science describes many useful herbal drugs for such types of advanced diseases. Upavisha the plant poisons of low potency are mentioned in Agadtantra. Arka (Calotropis procera/ Calotropis gigantea) is one among these Upavisha is emerging as an effective anticancer drug. It shows various pharmacological activities such as Anticancer, Antimicrobial, Antiimplantation etc. Different parts of Arka are used to treat cancer. In current scenario number of synthetic anticancer drugs are used to treat cancer. These synthetic anticancer drugs are expensive and shows harmful adverse effects. Upavisha like Arka which is natural derivative may be cost effective & less harmful as Anticancer drug. Anticancer activity of Calotropis procera/Calotropis gigantea is reported in scientific journals. This review summarizes various In Vitro and In Vivo studies of anticancer activity of Upavisha Arka.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"9 1","pages":"175-181"},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82243789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-13DOI: 10.7897/2277-4572.096188
S. Alam, W. Ahmad, M. Rizwanullah, M. Muzammil
Introduction: A wound can be defined as the discontinuity in skin or mucus membrane. Healing is nothing but neogranulation in the depth and neo-epithelialization at the edges of the wound which ultimately results in the complete repair of such discontinuity. This case report deals with a patient of traumatic large wound at the heel who receives Unani management for wound healing. He was diagnosed as avulsion of pad of right heel with type-II diabetes mellitus. The treatment plan included mechanical debridement, cleaning with solution of alum powder (Sufuf-e-zaaj/alusol) and dressing with Marham-e-raal. The patient was advised to continue oral hypoglycemic agent with subcutaneous injection of insulin. On 85th day of treatment, the wound was healed by almost 98% and on subsequent 1st and 2nd follow up, each with a gap of 15 days, no recurrence of wound was recorded. Methodology: A male patient of traumatic wound was taken into study and given Unani management plan which included debridement, cleaning and washing with solution of Alum powder (Alusol)/ or, in Unani, Sufuf-e-zaaj and dressing of the wound with Marham-e-raal with full aseptic precautions for a period of about 3 months. Discussion: Wound healing is credited to muhallil(anti-inflammatory), daf’eta’ffun (antimicrobial), mujaffif (desiccant) and mundamil (wound healing) properties of Marham-e-raal due to presence of several phytoconstituents like camphor, linalool, borneol, cineole, terpenoids, Bergenin, Phenols and flavonoids, hopeaphenol, Oligostilbenoids, Monoterpenes, kaempferol, Quercetin and Catechin. Result: The wound completely healed at the end of 3 months with no recurrence noted on the 15th day of follow up after complete healing.
{"title":"HEALING OF A TRAUMATIC WOUND WITH HERBO-MEDICINAL OINTMENT; MARHAM-E-RAAL: A CASE STUDY","authors":"S. Alam, W. Ahmad, M. Rizwanullah, M. Muzammil","doi":"10.7897/2277-4572.096188","DOIUrl":"https://doi.org/10.7897/2277-4572.096188","url":null,"abstract":"Introduction: A wound can be defined as the discontinuity in skin or mucus membrane. Healing is nothing but neogranulation in the depth and neo-epithelialization at the edges of the wound which ultimately results in the complete repair of such discontinuity. This case report deals with a patient of traumatic large wound at the heel who receives Unani management for wound healing. He was diagnosed as avulsion of pad of right heel with type-II diabetes mellitus. The treatment plan included mechanical debridement, cleaning with solution of alum powder (Sufuf-e-zaaj/alusol) and dressing with Marham-e-raal. The patient was advised to continue oral hypoglycemic agent with subcutaneous injection of insulin. On 85th day of treatment, the wound was healed by almost 98% and on subsequent 1st and 2nd follow up, each with a gap of 15 days, no recurrence of wound was recorded. Methodology: A male patient of traumatic wound was taken into study and given Unani management plan which included debridement, cleaning and washing with solution of Alum powder (Alusol)/ or, in Unani, Sufuf-e-zaaj and dressing of the wound with Marham-e-raal with full aseptic precautions for a period of about 3 months. Discussion: Wound healing is credited to muhallil(anti-inflammatory), daf’eta’ffun (antimicrobial), mujaffif (desiccant) and mundamil (wound healing) properties of Marham-e-raal due to presence of several phytoconstituents like camphor, linalool, borneol, cineole, terpenoids, Bergenin, Phenols and flavonoids, hopeaphenol, Oligostilbenoids, Monoterpenes, kaempferol, Quercetin and Catechin. Result: The wound completely healed at the end of 3 months with no recurrence noted on the 15th day of follow up after complete healing.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80361863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-13DOI: 10.7897/2277-4572.096192
P. Chhabra, Ushasi Ghosh Chaudhury, Amrita Paul
Zingiber officinale Rosc. is well known common medicinal plant of India. The plant has got good medicinal importance. It is an herbaceous perennial plant of the family Zingiberaceae/ Scitamineae. It is a large tuberous plant with elongated leafy stems, spike inflorescence having yellow green flower. Adraka (Ginger) is the underground rhizome of the plant. It is cultivated extensively in almost all tropical and subtropical countries like India, China, Africa, and Australia. The World Health Organization (WHO) estimates that about 80% of people living in developing Countries depend on traditional medicines for their primary health care requirements. Shunthi is the dried form of Adraka and is prepared by boiling and drying the freshly peeled ginger root in alkaline solution (mostly quick lime) and dried in hot sunlight. In India kitchen ginger and shunthi are one of the important ingredients.
{"title":"A REVIEW ON SHUNTHI (Zingiber officinale Rosc.) WITH SPECIAL REFERENCE TO NIGHANTUS","authors":"P. Chhabra, Ushasi Ghosh Chaudhury, Amrita Paul","doi":"10.7897/2277-4572.096192","DOIUrl":"https://doi.org/10.7897/2277-4572.096192","url":null,"abstract":"Zingiber officinale Rosc. is well known common medicinal plant of India. The plant has got good medicinal importance. It is an herbaceous perennial plant of the family Zingiberaceae/ Scitamineae. It is a large tuberous plant with elongated leafy stems, spike inflorescence having yellow green flower. Adraka (Ginger) is the underground rhizome of the plant. It is cultivated extensively in almost all tropical and subtropical countries like India, China, Africa, and Australia. The World Health Organization (WHO) estimates that about 80% of people living in developing Countries depend on traditional medicines for their primary health care requirements. Shunthi is the dried form of Adraka and is prepared by boiling and drying the freshly peeled ginger root in alkaline solution (mostly quick lime) and dried in hot sunlight. In India kitchen ginger and shunthi are one of the important ingredients.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83250351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-13DOI: 10.7897/2277-4572.096189
J. Keerthana, Prakash L Hegde, Vijay Javagal
Usheera (Vetiveria zizanioides Linn. Nash) possesses a great therapeutic value in the traditional Ayurvedic medicine and is widely distributed in India. Apart from the medicinal value, the culms are used for sweeping, scenting clothes and also as soil binders. In Ayurvedic literature, the plant has been mentioned from Veda Kala to Nighantu Kala. Hence in a view of immense medicinal importance of the plant this review is therefore compile all the information related to Usheera.
{"title":"USHEERA (Vetiveria zizanioides Linn. Nash): A DRUG REVIEW","authors":"J. Keerthana, Prakash L Hegde, Vijay Javagal","doi":"10.7897/2277-4572.096189","DOIUrl":"https://doi.org/10.7897/2277-4572.096189","url":null,"abstract":"Usheera (Vetiveria zizanioides Linn. Nash) possesses a great therapeutic value in the traditional Ayurvedic medicine and is widely distributed in India. Apart from the medicinal value, the culms are used for sweeping, scenting clothes and also as soil binders. In Ayurvedic literature, the plant has been mentioned from Veda Kala to Nighantu Kala. Hence in a view of immense medicinal importance of the plant this review is therefore compile all the information related to Usheera.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"52 1","pages":"156-161"},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87610561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-10-08DOI: 10.7897/2277-4572.095185
Mahesh Kumar
{"title":"PROTECTIVE SAGACITY FOR CORONA WARRIORS DURING COVID-19 PATIENT CARE: A REVIEW","authors":"Mahesh Kumar","doi":"10.7897/2277-4572.095185","DOIUrl":"https://doi.org/10.7897/2277-4572.095185","url":null,"abstract":"","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"86 1","pages":"139-141"},"PeriodicalIF":0.0,"publicationDate":"2020-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76855356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-29DOI: 10.7897/2277-4572.095182
Smitha Gandra, S. S. Reddy, Sakalabattula Nagasri, Raju Jukanti, Vyshnavi
{"title":"DEVELOPMENT AND EVALUATION OF BAZEDOXIFENE ACETATE LOADED PROLIPOSOMES FOR EFFECTIVE ORAL DELIVERY","authors":"Smitha Gandra, S. S. Reddy, Sakalabattula Nagasri, Raju Jukanti, Vyshnavi","doi":"10.7897/2277-4572.095182","DOIUrl":"https://doi.org/10.7897/2277-4572.095182","url":null,"abstract":"","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"5 1 1","pages":"125-131"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89620722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-29DOI: 10.7897/2277-4572.095184
D. Akhtar, M. Ansari, S. Alam, W. Ahmad
{"title":"EFFICACY OF HERBO-MEDICINAL FORMULATION IN HAEMORRHOIDS: AN OPEN LABELLED CLINICAL STUDY","authors":"D. Akhtar, M. Ansari, S. Alam, W. Ahmad","doi":"10.7897/2277-4572.095184","DOIUrl":"https://doi.org/10.7897/2277-4572.095184","url":null,"abstract":"","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"14 1","pages":"135-138"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84553242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-29DOI: 10.7897/2277-4572.095183
Shah Fasal, Junaid Nazir Dandroo
{"title":"RISK FACTORS IN A SAMPLE POPULATION OF HAEMORRHOIDS: AN OBSERVATIONAL STUDY","authors":"Shah Fasal, Junaid Nazir Dandroo","doi":"10.7897/2277-4572.095183","DOIUrl":"https://doi.org/10.7897/2277-4572.095183","url":null,"abstract":"","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"10 1","pages":"132-134"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79450576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-29DOI: 10.7897/2277-4572.095180
Afroja Yeasmin Akhtar Roji, Abichal Chattopadhyay, Apala Sengupta, G. Mukherjee
{"title":"STUDIES ON THE CONCEPT OF OJA AND ITS EVALUATION IN RASAVAHA SHROTODUSHTI: A PROSPECTIVE RANDOMIZED COHORT STUDY","authors":"Afroja Yeasmin Akhtar Roji, Abichal Chattopadhyay, Apala Sengupta, G. Mukherjee","doi":"10.7897/2277-4572.095180","DOIUrl":"https://doi.org/10.7897/2277-4572.095180","url":null,"abstract":"","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"42 1","pages":"113-120"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85293195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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