Pub Date : 2022-10-26DOI: 10.7897/2277-4572.115236
Subhashitha S, Ashitha Meharooz, Haseena ., Nasheel Shereen, Ravi Kumar
The aim of the present investigation is to prepare mefenamic acid microspheres by ionic gelation technique. A total of three formulations were prepared by altering the polymer ratio. The obtained microspheres were evaluated for drug entrapment efficiency, swelling index, and in vitro drug release. Out of three formulation F3 formulation i.e., (1:2) drug: polymer ratio was found to best formulation with high product yield, Drug entrapment efficiency, Swelling index, and in vitro drug release.
{"title":"FORMULATION AND EVALUATION OF MEFENAMIC ACID MICROSPHERES BY IONIC GELATION TECHNIQUE","authors":"Subhashitha S, Ashitha Meharooz, Haseena ., Nasheel Shereen, Ravi Kumar","doi":"10.7897/2277-4572.115236","DOIUrl":"https://doi.org/10.7897/2277-4572.115236","url":null,"abstract":"The aim of the present investigation is to prepare mefenamic acid microspheres by ionic gelation technique. A total of three formulations were prepared by altering the polymer ratio. The obtained microspheres were evaluated for drug entrapment efficiency, swelling index, and in vitro drug release. Out of three formulation F3 formulation i.e., (1:2) drug: polymer ratio was found to best formulation with high product yield, Drug entrapment efficiency, Swelling index, and in vitro drug release.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81251780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-30DOI: 10.7897/2277-4572.114235
Ankita Tripathi, Shubham Srivastava, K. Bhardwaj, Sristi Raj, N. .
Epilepsy is a severe neurological illness characterized by abnormal, recurring, and synchronized brain discharges. Long-term recurring seizure attacks can cause substantial brain function loss, as seen in people with temporal lobe epilepsy. Controlling seizure events is critical for epilepsy therapy and prognosis. The disease is more common in developing countries than in developed countries. The causes of epilepsy include chemical imbalances such as low blood sugar or sodium, head injuries, drug abuse or withdrawal, alcohol withdrawal, stroke tumor affecting the blood vessels (vascular system) in the brain, hardening of the arteries (atherosclerosis) in the brain, brain tumours, and brain infections such as meningitis or encephalitis. Given the prevalence of epilepsy and the challenges associated with currently available antiepileptic medicines, such as side effects, resistance, safety concerns, and high cost, screening models are utilized in epilepsy analysis. Screening models for seizures and epilepsy have been critical in expanding our understanding of the fundamental mechanisms underlying ictogenesis and epileptogenesis, as well as in the discovery and preclinical development of novel antiepileptic medicines (AEDs). Diverse screening models of epilepsy have been developed in recent years to imitate various seizure forms, with no clear advantages or disadvantages. In this study, we will cover the numerous screening models for epilepsy, which will aid in gaining a better understanding of the disease.
{"title":"VALIDATION OF SCREENING MODELS OF EPILEPSY: A REVIEW","authors":"Ankita Tripathi, Shubham Srivastava, K. Bhardwaj, Sristi Raj, N. .","doi":"10.7897/2277-4572.114235","DOIUrl":"https://doi.org/10.7897/2277-4572.114235","url":null,"abstract":"Epilepsy is a severe neurological illness characterized by abnormal, recurring, and synchronized brain discharges. Long-term recurring seizure attacks can cause substantial brain function loss, as seen in people with temporal lobe epilepsy. Controlling seizure events is critical for epilepsy therapy and prognosis. The disease is more common in developing countries than in developed countries. The causes of epilepsy include chemical imbalances such as low blood sugar or sodium, head injuries, drug abuse or withdrawal, alcohol withdrawal, stroke tumor affecting the blood vessels (vascular system) in the brain, hardening of the arteries (atherosclerosis) in the brain, brain tumours, and brain infections such as meningitis or encephalitis. Given the prevalence of epilepsy and the challenges associated with currently available antiepileptic medicines, such as side effects, resistance, safety concerns, and high cost, screening models are utilized in epilepsy analysis. Screening models for seizures and epilepsy have been critical in expanding our understanding of the fundamental mechanisms underlying ictogenesis and epileptogenesis, as well as in the discovery and preclinical development of novel antiepileptic medicines (AEDs). Diverse screening models of epilepsy have been developed in recent years to imitate various seizure forms, with no clear advantages or disadvantages. In this study, we will cover the numerous screening models for epilepsy, which will aid in gaining a better understanding of the disease.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88147854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-30DOI: 10.7897/2277-4572.114233
V. Bhat, Nisha Ullas Naik, Kushal R, Sinchana A Shetty, V. Shetty, Surekha Devadiga, R. Nayak
Feet are our body’s substructure, so keeping them healthy is indispensable to our overall health. From ancient time variety of herbs have been used to treat different foot diseases. In this study, the main aim is the preparation of foot cream using Ficus racemosa (cluster fig) plant extract. Its biological active ingredients, such as Gluconal acetate, β-sitosterol, lupeol and lupeol acetate produces wound healing, antioxidant, anti-inflammatory, and anti-fungal activity over skin surface. The main objective of this research work includes the complete qualification of wound healing or screening, and it is useful to obtain good foot cream for topical application. Preparation of foot cream using Ficus racemosa was done and its evaluation was carried out on various parameters. The used product is compatible with other ingredients present in the formulation.
{"title":"FORMULATION AND EVALUATION OF FOOT CREAM FROM FICUS RACEMOSA","authors":"V. Bhat, Nisha Ullas Naik, Kushal R, Sinchana A Shetty, V. Shetty, Surekha Devadiga, R. Nayak","doi":"10.7897/2277-4572.114233","DOIUrl":"https://doi.org/10.7897/2277-4572.114233","url":null,"abstract":"Feet are our body’s substructure, so keeping them healthy is indispensable to our overall health. From ancient time variety of herbs have been used to treat different foot diseases. In this study, the main aim is the preparation of foot cream using Ficus racemosa (cluster fig) plant extract. Its biological active ingredients, such as Gluconal acetate, β-sitosterol, lupeol and lupeol acetate produces wound healing, antioxidant, anti-inflammatory, and anti-fungal activity over skin surface. The main objective of this research work includes the complete qualification of wound healing or screening, and it is useful to obtain good foot cream for topical application. Preparation of foot cream using Ficus racemosa was done and its evaluation was carried out on various parameters. The used product is compatible with other ingredients present in the formulation.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90906343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meningitis is a condition caused by the inflammation of the meninges. Meningitis can be caused by bacteria, viruses, fungi, parasites, and amebic. Interestingly some meningitis is infectious, while other is non-infectious. The non-infectious causes of meningitis are autoimmune illnesses, cancer/paraneoplastic syndromes, and medication responses. There are several risk factors associated with meningitis, like a defect in the dural, alcoholism, age, medical condition, some kind of exposure, and so on. Since meningitis is a serious and delicate condition, the need of several screening models is required to validate meningitis. These models depend on thematical calculations like regression models, multiple regression models, and logistic models, and some animal models are also there for meningitis. Hence, here we discussed meningitis and models briefly.
{"title":"VALIDATION OF SCREENING MODEL FOR MENINGITIS: A REVIEW","authors":"Ankita Tripathi, Utsav Gupta, Pooja Chaurasiya, Priya Pandey, Sristi Raj","doi":"10.7897/2277-4572.114234","DOIUrl":"https://doi.org/10.7897/2277-4572.114234","url":null,"abstract":"Meningitis is a condition caused by the inflammation of the meninges. Meningitis can be caused by bacteria, viruses, fungi, parasites, and amebic. Interestingly some meningitis is infectious, while other is non-infectious. The non-infectious causes of meningitis are autoimmune illnesses, cancer/paraneoplastic syndromes, and medication responses. There are several risk factors associated with meningitis, like a defect in the dural, alcoholism, age, medical condition, some kind of exposure, and so on. Since meningitis is a serious and delicate condition, the need of several screening models is required to validate meningitis. These models depend on thematical calculations like regression models, multiple regression models, and logistic models, and some animal models are also there for meningitis. Hence, here we discussed meningitis and models briefly.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"2000 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88303990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present work deals with the preparation and standardization of chitrakadi vati. All the parameters of both market formulation (MF1 & MF2) and Laboratory formulation (LF) were found to be within the limit prescribed in pharmacopoeia. Average weight and weigh variation of LF was 2057 mg and 0.2±0.1 %, disintegration time was 8±2 min, hardness was 4.6±0.2 Kg/cm2 , friability was 0.9722±0.2 %, ash values were 2.4 % (acid insoluble ash) and 2.15 % (water soluble ash), extractive values were 5.6 % (acid insoluble extractive) and 7.25 % (water soluble extractive). In order to ensure quality and stability of final product, some of the important chemical markers has been separated from the mixture and for analysis by high performance thin layer chromatography was selected for qualitative and quantitative purpose. The results of standardization parameters showed marked difference among three, which fingers to authenticity of market formulations. Even HPTLC fingerprinting showed some ingredients in market formulations were taken adulterated or inferior in quality. The HPTLC method for fingerprinting was found to be precise and accurate to quantify three chemical markers plumbagin (0.84%), piperine (0.92%), zingiberene (0.71%), and it further characterized by IR, NMR, Mass spectra.
{"title":"PREPARATION AND STANDARDIZATION OF CHITRAKADI VATI","authors":"Shilpa Patel, Nikunj Patadiya, Pooja Makvana, Rikin Patel","doi":"10.7897/2277-4572.113230","DOIUrl":"https://doi.org/10.7897/2277-4572.113230","url":null,"abstract":"The present work deals with the preparation and standardization of chitrakadi vati. All the parameters of both market formulation (MF1 & MF2) and Laboratory formulation (LF) were found to be within the limit prescribed in pharmacopoeia. Average weight and weigh variation of LF was 2057 mg and 0.2±0.1 %, disintegration time was 8±2 min, hardness was 4.6±0.2 Kg/cm2 , friability was 0.9722±0.2 %, ash values were 2.4 % (acid insoluble ash) and 2.15 % (water soluble ash), extractive values were 5.6 % (acid insoluble extractive) and 7.25 % (water soluble extractive). In order to ensure quality and stability of final product, some of the important chemical markers has been separated from the mixture and for analysis by high performance thin layer chromatography was selected for qualitative and quantitative purpose. The results of standardization parameters showed marked difference among three, which fingers to authenticity of market formulations. Even HPTLC fingerprinting showed some ingredients in market formulations were taken adulterated or inferior in quality. The HPTLC method for fingerprinting was found to be precise and accurate to quantify three chemical markers plumbagin (0.84%), piperine (0.92%), zingiberene (0.71%), and it further characterized by IR, NMR, Mass spectra.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91515366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.7897/2277-4572.113231
Sadhana Nalawade, D. Padavi
According to Ayurveda Katigat vata is one of the types of Vata vyadhi explained in our ancient Ayurvedic text. It arises due to Prakop of Aata dosha and Asthi dhatu kshaya. Similarly Lumbar Spondylosis is a degenerative disorder affecting the discs and the vertebral bodies of the lumbar spine. Patients with lumbar spondylosis have pain in their axial spine which affects most of the people in the later stage of their lives. A 75 years old female having a history of katigat vata for the last 6 years so she approached Dr. DY Patil Ayurvedic Hospital for Ayurvedic management. Patient was having a progressive pain in her lower back with restricted movements. She was treated for 75 days including Panchakarma therapies. The response to the treatment was recorded and therapeutic effects were evaluated with a reduction of clinical symptoms of the patient. This case study evaluates that Ayurvedic management, in this case, was very effective treating Katigata vata successfully without any side effects.
{"title":"A CASE REPORT ON KATIGAT VATA WITH SPECIAL REFERENCE TO LUMBAR SPONDYLOSIS","authors":"Sadhana Nalawade, D. Padavi","doi":"10.7897/2277-4572.113231","DOIUrl":"https://doi.org/10.7897/2277-4572.113231","url":null,"abstract":"According to Ayurveda Katigat vata is one of the types of Vata vyadhi explained in our ancient Ayurvedic text. It arises due to Prakop of Aata dosha and Asthi dhatu kshaya. Similarly Lumbar Spondylosis is a degenerative disorder affecting the discs and the vertebral bodies of the lumbar spine. Patients with lumbar spondylosis have pain in their axial spine which affects most of the people in the later stage of their lives. A 75 years old female having a history of katigat vata for the last 6 years so she approached Dr. DY Patil Ayurvedic Hospital for Ayurvedic management. Patient was having a progressive pain in her lower back with restricted movements. She was treated for 75 days including Panchakarma therapies. The response to the treatment was recorded and therapeutic effects were evaluated with a reduction of clinical symptoms of the patient. This case study evaluates that Ayurvedic management, in this case, was very effective treating Katigata vata successfully without any side effects.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89586194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-27DOI: 10.7897/2277-4572.111225
J. ., Sidram Guled
Introduction: The incidence of Obesity is increasing day by day in more percentage due to sedentary lifestyle and food habits and is resulting into many serious systemic complications. Sthoulya is kapha pradhana and medo-pradoshaja vyadhi. Charaka samhita mentioned Sthoulya disease under the eight varieties of personalities which are designated as Astha Nindita Purusha. Sthoulya is kapha and meda predominant vyadhi and vamana karma is prime therapy and it eliminates kapha and meda. Udvartana is another important therapy in Sthoulya that results in kapha meda vilayana and hence the present study is entitled as “Clinical study on effect of Vamana and Udvartana karma in the management of Sthoulya” was planned. Aims and Objectives: To evaluate the efficacy of the Vamana karma, Udvartana in Sthoulya and to compare and assess the effect of both the therapies. Materials And Methods: Total 30 patients were selected, distributed in 2 equal groups, Group A treated with Vamana karma and Group B treated with Udvartana. Observations And Results: The progress was assessed based on subjective parameters considered by giving scores to the clinical signs and symptoms and objective parameters were done before treatment and after treatment with a specially prepared case proforma. Discussion and Conclusion: All the patients in both groups were responded positively without any complications. Group A with Vamana showed highly significant results in symptoms; Atikshudha, Ati pipasa, Nidradhikya, Shrama and Hyperlipidemia. Group B with Udvartana also showed highly significant results in symptoms like Nidradhikya, Swedadhikya, Dourgandya, Shrama and Alasya.
{"title":"CLINICAL STUDY ON EFFECT OF VAMANA AND UDVARTANA KARMA IN THE MANAGEMENT OF STHOULYA","authors":"J. ., Sidram Guled","doi":"10.7897/2277-4572.111225","DOIUrl":"https://doi.org/10.7897/2277-4572.111225","url":null,"abstract":"Introduction: The incidence of Obesity is increasing day by day in more percentage due to sedentary lifestyle and food habits and is resulting into many serious systemic complications. Sthoulya is kapha pradhana and medo-pradoshaja vyadhi. Charaka samhita mentioned Sthoulya disease under the eight varieties of personalities which are designated as Astha Nindita Purusha. Sthoulya is kapha and meda predominant vyadhi and vamana karma is prime therapy and it eliminates kapha and meda. Udvartana is another important therapy in Sthoulya that results in kapha meda vilayana and hence the present study is entitled as “Clinical study on effect of Vamana and Udvartana karma in the management of Sthoulya” was planned. Aims and Objectives: To evaluate the efficacy of the Vamana karma, Udvartana in Sthoulya and to compare and assess the effect of both the therapies. Materials And Methods: Total 30 patients were selected, distributed in 2 equal groups, Group A treated with Vamana karma and Group B treated with Udvartana. Observations And Results: The progress was assessed based on subjective parameters considered by giving scores to the clinical signs and symptoms and objective parameters were done before treatment and after treatment with a specially prepared case proforma. Discussion and Conclusion: All the patients in both groups were responded positively without any complications. Group A with Vamana showed highly significant results in symptoms; Atikshudha, Ati pipasa, Nidradhikya, Shrama and Hyperlipidemia. Group B with Udvartana also showed highly significant results in symptoms like Nidradhikya, Swedadhikya, Dourgandya, Shrama and Alasya.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"398 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82167001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-27DOI: 10.7897/2277-4572.111226
V. J, N. P
Objective: To evaluate in vitro antiurolithiatic activities of Pavonia zeylanica (L) Cav. Material and Methods: Whole plant of Ethanolic extract of Pavonia zeylanica was prepared and arranged in the three different concentrations (10mg/ml, 20mg/ml, and 30mg/ml). In vitro antiurolithiatic activity of Ethanolic extract of Pavonia zeylanica through turbidometric and titrimetric method was tested in terms of inhibition of calcium oxalate by nucleation and aggregation and dissolution of calcium oxalate, using the standard drug. Results: Standard drug has high percentage inhibition and dissolution ability and thus Ethanolic extract of Pavonia zeylanica also have a good percentage inhibition and dissolution ability was comparable to standard drug. Conclusion: The study concludes that the Ethanolic extract of Pavonia zeylanica have inhibitory effect on calcium oxalate for nucleation and aggregation assay. It also showed good dissolution of calcium oxalate crystals, so this extract has the good protection against Urolithiasis activity
{"title":"EVALUATION OF IN VITRO ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF PAVONIA ZEYLANICA (L) CAV","authors":"V. J, N. P","doi":"10.7897/2277-4572.111226","DOIUrl":"https://doi.org/10.7897/2277-4572.111226","url":null,"abstract":"Objective: To evaluate in vitro antiurolithiatic activities of Pavonia zeylanica (L) Cav. Material and Methods: Whole plant of Ethanolic extract of Pavonia zeylanica was prepared and arranged in the three different concentrations (10mg/ml, 20mg/ml, and 30mg/ml). In vitro antiurolithiatic activity of Ethanolic extract of Pavonia zeylanica through turbidometric and titrimetric method was tested in terms of inhibition of calcium oxalate by nucleation and aggregation and dissolution of calcium oxalate, using the standard drug. Results: Standard drug has high percentage inhibition and dissolution ability and thus Ethanolic extract of Pavonia zeylanica also have a good percentage inhibition and dissolution ability was comparable to standard drug. Conclusion: The study concludes that the Ethanolic extract of Pavonia zeylanica have inhibitory effect on calcium oxalate for nucleation and aggregation assay. It also showed good dissolution of calcium oxalate crystals, so this extract has the good protection against Urolithiasis activity","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"149 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78035643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-30DOI: 10.7897/2277-4572.106219
R. ., Chandini Sg, A. R., A. S, A. S
Ayurveda is one of the field which carries a huge acceleration in revitalisation. The rejuvenation of local health tradition had been continued after independence, though in a slow speed. The practice of Marma Chikitsa is more prevalent in Kerala and South Tamil Nadu and plays a key role even today. The importance of Ayurveda is even accepted by Western scholars in this high-tech era is worth to note. According to day-to-day clinical practise, Ayurvedic treatment shows better results in mild, moderate and severe cases of Janumarmabhighata. Hence, this study was undertaken to find out effective treatment for the Vikaras caused by Janumarmabhighata. 30 patients were selected for the current study according to derived inclusion and exclusion criteria, from OPD and IPD of Government Ayurveda college hospital, Trivandrum, Kerala. The case history of each patient was recorded as per the proforma designed. 10 patients were each tabulated under three groups containing janumarmabhighata lakshana like A, B, C groups (mild/moderate/severe) respectively, after assessing subjective and objective symptoms. Similarly, treatment protocol also was framed out in three different categories according to general line of management for sandhimarma kshata and janumarmabhighata. Remarkable improvement was noticed in each category after treatment. Assessment of clinical recovery in terms of pain, tenderness, swelling, wasting, muscle strength, flexion and extension in 3 groups were statistically also significant.
{"title":"A PRAGMATIC CLINICAL APPROACH ON EFFECTIVENESS AND MANAGEMENT OF JANUMARMABHIGHATA","authors":"R. ., Chandini Sg, A. R., A. S, A. S","doi":"10.7897/2277-4572.106219","DOIUrl":"https://doi.org/10.7897/2277-4572.106219","url":null,"abstract":"Ayurveda is one of the field which carries a huge acceleration in revitalisation. The rejuvenation of local health tradition had been continued after independence, though in a slow speed. The practice of Marma Chikitsa is more prevalent in Kerala and South Tamil Nadu and plays a key role even today. The importance of Ayurveda is even accepted by Western scholars in this high-tech era is worth to note. According to day-to-day clinical practise, Ayurvedic treatment shows better results in mild, moderate and severe cases of Janumarmabhighata. Hence, this study was undertaken to find out effective treatment for the Vikaras caused by Janumarmabhighata. 30 patients were selected for the current study according to derived inclusion and exclusion criteria, from OPD and IPD of Government Ayurveda college hospital, Trivandrum, Kerala. The case history of each patient was recorded as per the proforma designed. 10 patients were each tabulated under three groups containing janumarmabhighata lakshana like A, B, C groups (mild/moderate/severe) respectively, after assessing subjective and objective symptoms. Similarly, treatment protocol also was framed out in three different categories according to general line of management for sandhimarma kshata and janumarmabhighata. Remarkable improvement was noticed in each category after treatment. Assessment of clinical recovery in terms of pain, tenderness, swelling, wasting, muscle strength, flexion and extension in 3 groups were statistically also significant.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85808028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-30DOI: 10.7897/2277-4572.106221
Arpita H R, Anand Katti
Health is a state of equilibrium of doshas, dhatu, mala, atma and indriya. In deceased condition it is necessary to maintain the balance between the doshas and bringing back to their normalcy. Ayurveda had described various tools for diagnosing various diseases one among that is roga and rogi pariksha. Roga pariksha is done by assessing nidana panchakas while rogi pariksha is done by dwividha, trividha, chaturvida, ashtavida, dashavidha pariksha.In the context of desha pariksha Acharya Charaka has mentioned bhumi pariksha and In Atura pariksha he has mentioned atura parijnana hetu which explains in detail about relationship between the desha and atura from the birth how these factors contribute a role in developing a disease, which helps in diagnosing the condition of the patient, health geography deals with the interaction between people and environment, It conceptualize the role of place, location and geography in health ,well-being and disease.
{"title":"ATURA PARIJNANA HETU VIS-A-VIS HEALTH GEOGRAPHY: A REVIEW","authors":"Arpita H R, Anand Katti","doi":"10.7897/2277-4572.106221","DOIUrl":"https://doi.org/10.7897/2277-4572.106221","url":null,"abstract":"Health is a state of equilibrium of doshas, dhatu, mala, atma and indriya. In deceased condition it is necessary to maintain the balance between the doshas and bringing back to their normalcy. Ayurveda had described various tools for diagnosing various diseases one among that is roga and rogi pariksha. Roga pariksha is done by assessing nidana panchakas while rogi pariksha is done by dwividha, trividha, chaturvida, ashtavida, dashavidha pariksha.In the context of desha pariksha Acharya Charaka has mentioned bhumi pariksha and In Atura pariksha he has mentioned atura parijnana hetu which explains in detail about relationship between the desha and atura from the birth how these factors contribute a role in developing a disease, which helps in diagnosing the condition of the patient, health geography deals with the interaction between people and environment, It conceptualize the role of place, location and geography in health ,well-being and disease.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75190346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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