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Informational flows, mechanisms and models in protein synthesis 蛋白质合成中的信息流、机制和模型
Pub Date : 2016-06-06 DOI: 10.11606/S1678-31662016000100009
M. Casanueva, R. Madrigal
This paper starts with an emphasis on the increasing importance of diagrams in philosophy of science, highlighting their capacity for heuristic evocation, their usefulness for representation and calculus, and their power of synthesis. Next, we present how diagrams are important and have been well received within the new Mechanistic philosophy of science, which contrasts with this school’s rejection of approaches centered on laws and models. Finally, We propose an interpretation of laws and mechanistic explanations that conciliates the concepts of mechanism and law. The mechanism of protein synthesis is used as an illustrative case
本文首先强调了图表在科学哲学中日益增长的重要性,强调了它们的启发式唤起能力,它们对表示和演算的有用性,以及它们的综合能力。接下来,我们介绍图表是如何重要的,并且在新的机械论科学哲学中得到了很好的接受,这与该学派拒绝以定律和模型为中心的方法形成了鲜明对比。最后,我们提出了一种协调机制和法律概念的法律解释和机械解释。以蛋白质合成的机理为例进行说明
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引用次数: 0
O valor da moeda em Oresme e Copérnico 奥雷斯马和哥白尼的货币价值
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400002
M. Custódio, Sueli Custódio
This paper presents the notion of value applied to the analysis of currency, elaborated by Nicole Oresme, in 1355, and Nicolas Copernicus, in 1526. It shows that, to these authors, currency value must be stable and determined by the community engaged in activites of buying and selling. It also shows how they are opposed to instability of value, especially to its devaluation promoted by the government. It argues that both authors create systems for measuring and controlling of currency value in times of monetary turmoil. According to Oresme and Copernicus, instability of currency value not only keeps commerce faraway, in other kingdoms or republics, but also reveals the misconduct of the prince, the one who is invested with political and monetary authority in European societies of the fourteenth and sixteenth centuries.
本文提出了应用于货币分析的价值概念,由尼科尔·奥勒斯姆(Nicole Oresme)于1355年和尼古拉斯·哥白尼(Nicolas Copernicus)于1526年阐述。这表明,对这些作者来说,货币价值必须是稳定的,并由从事买卖活动的社区决定。这也表明他们是如何反对价值的不稳定,特别是反对政府推动的货币贬值。文章认为,两位作者都创造了在货币动荡时期衡量和控制货币价值的体系。根据奥勒斯姆和哥白尼的观点,货币价值的不稳定不仅使商业远离其他王国或共和国,而且还揭示了君主的不当行为,在14世纪和16世纪的欧洲社会中,君主被赋予了政治和货币权力。
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引用次数: 0
Sobre as origens da concepção freudiana de ciências da natureza 论弗洛伊德自然科学概念的起源
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400004
V. Carvalho, Luiz Roberto Monzani
This article examines some of the theoretical outlooks Freud used to acquire the epistemological values that underlie the foundation of his notion of natural science. On the one hand Freud was familiar with the ideas of specific authors (Brucke, Helmholtz, among others), who had made major contributions that support of psychology's status as a science by appealing to physics and physiology. On the other hand, his contact with certain philosophers (Brentano and Stuart Mill) allowed him to use their defenses of psychology's scientific status without abandoning naturalism and without recourse to physiology. Our historical evaluation of these struggles supports that Freud was affected by various points of view concerning psychology's standing within the natural sciences. Owing to the diverse influences on Freud, we need to figure out how we can put his epistemology and his concept of naturalism into perspective.
本文考察了弗洛伊德用来获得认识论价值的一些理论观点,这些认识论价值构成了他的自然科学概念的基础。一方面,弗洛伊德熟悉某些作者(布鲁克、亥姆霍兹等人)的思想,这些作者通过求助于物理学和生理学,为支持心理学作为一门科学的地位做出了重大贡献。另一方面,他与某些哲学家(布伦塔诺和斯图亚特·密尔)的接触使他能够在不放弃自然主义和不诉诸生理学的情况下,利用他们对心理学科学地位的辩护。我们对这些斗争的历史评价支持弗洛伊德受到关于心理学在自然科学中的地位的各种观点的影响。由于弗洛伊德受到了各种各样的影响,我们需要弄清楚如何正确看待他的认识论和他的自然主义概念。
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引用次数: 0
Emergência sem níveis 无级别紧急情况
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400006
Luiz Henrique Menegon Dutra
This paper deals with the question of downward causation in connection with emergent systems. Beginning with the comments offered by Emmeche, Koppe, and Stjernfelt (2000), which are criticized here, and partially based on those of Pattee (2000), the paper puts forward an interpretation of the kind of relation that exists between the basal conditions for a given event and the event itself, and the relations between a given system as a whole and its parts making use of the concepts of community and internal purposiveness, concepts due to Kant.
本文讨论了紧急系统的下向因果关系问题。本文以本文所批评的Emmeche、Koppe和Stjernfelt(2000)的评论为开端,部分以Pattee(2000)的评论为基础,利用共同体和内部合目的性的概念,对给定事件的基本条件与事件本身之间的关系,以及给定系统作为一个整体与其各部分之间的关系提出了一种解释。
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引用次数: 0
A epidemia de más condutas na ciência: o fracasso do tratamento moralizador 科学中不良行为的流行:道德治疗的失败
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400007
Marcos Barbosa de Oliveira
The article deals with the proliferation of violations of ethical norms of science, that started to develop a few decades ago. It will be referred to as "the epidemic". The most important types of these violations are varieties of fraud (mainly falsification and fabrication of empirical data), and such forms of author misconduct as plagiarism, self-plagiarism, etc. The article is divided into six sections. In the first, the topic is introduced and some terminology clarified. In the second, evidence is presented which corroborates the existence of the epidemic. The third deals with the reaction to the epidemic, by characterizing its dynamics in terms of being dominated by conflict between two positions: the moralizing one - which promotes the application of the moralizing treatment to combat the epidemic; and the negationist one - which tends to deny the existence of the epidemic, and resists the moralizing measures. The fourth explores the causes of the epidemic. A distinction is introduced between productivism and productionism, and an analysis is proposed of the ways productivism fosters violations of ethical norms of science. The fifth consists of a critique of the moralizing treatment, based on its inadequacies, mainly its inefficacy. The conclusion points to an alternative to the moralizing treatment.
这篇文章讨论了几十年前开始出现的违反科学伦理规范的现象。它将被称为“流行病”。这些违规行为中最重要的类型是各种欺诈行为(主要是伪造和捏造经验数据),以及作者的不当行为,如抄袭、自我抄袭等。这篇文章分为六个部分。本文首先介绍了本文的主题,并对一些术语进行了澄清。在第二部分中,提出了证实这种流行病存在的证据。第三部分是关于对流行病的反应,描述了两种立场之间的冲突所主导的动态:道德化的一方提倡采用道德化的治疗方法来对抗流行病;而否定主义倾向于否认流行病的存在,并抵制道德措施。第四章探讨了艾滋病流行的原因。介绍了生产主义和生产主义之间的区别,并对生产主义助长违反科学伦理规范的方式进行了分析。第五部分是对道德化治疗的批判,基于它的不足,主要是它的无效。结论指出了道德治疗的另一种选择。
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引用次数: 8
Do mistério das eras do gelo às mudanças climáticas abruptas 从冰河时代的神秘到突然的气候变化
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400005
José Alberto Corrêa Leite
O problema da era do gelo foi o primeiro e, ate algumas decadas atras, o unico debate relevante sobre as mudancas climaticas, emergindo como uma discussao da geologia, que nao foi capaz de equaciona-lo. Ficou como um misterio que transitou, no seculo XIX, pela matematica e astronomia e foi objeto de especulacoes na geofisica e geoquimica sem que uma solucao satisfatoria fosse encontrada. A resposta basica para a ocorrencia das eras do gelo foi dada por Milankovitch, com sua teoria matematica da insolacao, na decada de 1940. Todavia somente a consolidacao da paleoclimatologia, na decada de 1970, ofereceu as evidencias necessarias para comprova-la. O refinamento desses estudos paleoclimatologicos acabou revelando, todavia, um fenomeno inesperado, a saber, que as transicoes de estados de equilibrio no sistema climatico aconteceram muito rapidamente no passado. As mudancas climaticas da era do gelo do pleistoceno ocorreram de maneira abrupta e radical, em uma negacao do gradualismo. Em consequencia, o atual aquecimento global deve ser visto como um fenomeno muito mais perigoso e imprevisivel do que usualmente apresentado.
冰河时代的问题是第一个,直到几十年前,关于气候变化的唯一相关辩论,它出现在一个无法将其等同起来的地质学讨论中。它就像一个谜,在19世纪通过数学和天文学,并成为地球物理和地球化学推测的对象,但没有找到一个令人满意的解决方案。20世纪40年代,米兰科维奇用他的日晒数学理论给出了冰河时代出现的基本答案。然而,直到20世纪70年代古气候学的巩固,才提供了必要的证据来证明这一点。然而,这些古气候学研究的改进揭示了一个意想不到的现象,即气候系统平衡态的转变在过去发生得非常快。更新世冰河时代的气候变化发生得突然而彻底,否定了渐进主义。因此,当前的全球变暖必须被视为一种比通常呈现的更为危险和不可预测的现象。
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引用次数: 4
Materialidade e sociedade: tendências sociotécnicas em tecnologias móveis 物质性与社会:移动技术的社会技术趋势
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400009
Pedro Filipe Xavier Mendonça
The delimitation of defining lines of certain technological development is something that several authors already established. This kind of approach is inspired in similar task applied to science. In this work it is intended to present some lines, that we call tendencies, which mark mobile technologies development, like mobile phones, smartphones or tablets. This work makes an analysis of some artifacts and its features, which make some directions and hegemonic dominations, although they are not exclusive of these technologies. It is applied a sociotechnical analysis based on observation and on the use of this kind of technologies. The output is the identification of five tendencies: realism; techno-body continuity; priority to context; velocity; and compatibility/multi-functionality. This different sociotechnical forms allow the understanding of how these materialities are inscribed in social space, and how some projects are a result of social intentions. The proliferation of mobile technologies shows by itself the relevance of this approach in order to question technological future.
某些技术发展的定义线的界限是一些作者已经建立的东西。这种方法在应用于科学的类似任务中受到启发。在这项工作中,它旨在呈现一些线,我们称之为趋势,这标志着移动技术的发展,如移动电话,智能手机或平板电脑。本作品对一些人工制品及其特征进行了分析,这些人工制品虽然并不排斥这些技术,但却具有一定的方向性和霸权性。它是一种基于观察和使用这类技术的社会技术分析。结果是对五种倾向的识别:现实主义;techno-body连续性;语境优先;速度;和兼容性/多功能化。这种不同的社会技术形式使人们能够理解这些材料是如何被刻在社会空间中的,以及一些项目是如何成为社会意图的结果的。移动技术的扩散本身就表明了这种方法在质疑技术未来方面的相关性。
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引用次数: 1
Estilo de raciocínio e capilaridade técnico-cultural na química no século XVIII
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400003
Ronei Clécio Mocellin
In this paper I will identify a "style of reasoning" that is proper to to Chemistry and to point to the dissemination of its products and concepts. My aim is to explain some elements that characterize the style of thinking and engaging in Chemistry in the second half of the 18th century, its techno-cultural capillary action. The shaping of a chemical style of reasoning originated from the constancy of the techno-epistemic sites in which chemical knowledge is formed. Chemistry is a laboratory science, eminently technical and operative, i.e., it deals with a techno-scientific knowledge stricto sensu. A producer of artifacts, chemical science is inseparable from technique, technology and industry, in such a way that its epistemic identity is inseparable from its history. Its style marks a profound value in the technical culture of the homo faber, the power of acting upon nature and transforming it through manipulations and rearrangements.
在本文中,我将确定一种适合于化学的“推理风格”,并指出其产品和概念的传播。我的目的是解释18世纪下半叶化学的思维方式和参与方式的一些特征,以及它的技术文化毛细管作用。化学推理方式的形成源于化学知识形成的技术认知场所的恒常性。化学是一门实验室科学,具有突出的技术性和操作性,也就是说,它涉及严格意义上的技术科学知识。作为人工制品的生产者,化学科学与技术、技术和工业是分不开的,就像它的认知认同与它的历史是分不开的一样。它的风格标志着人类技术文化的深刻价值,即通过操纵和重组对自然进行作用和改造的力量。
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引用次数: 2
Trajetórias e divisão do trabalho no laboratório de genética humana 人类遗传学实验室的轨迹和劳动分工
Pub Date : 2015-12-01 DOI: 10.1590/S1678-31662015000400008
M. T. Ferreira
The article discusses the division of scientific labour among senior and junior researchers in a Brazilian research center for human and medical genetics. Starting with the contemporary debate on the progressive intertwining of science and technology - with progressive fusion of both, evoking notions such as technoscience - it is possible to verify, in this specific subarea, rising speed in data production that pressure scientists in different manners: through the rising cost of technological innovations and through the necessity for more complex methods of analysis. In this context I analyze issues concerning the specialization of scientific work, the separation between conception and execution as well as correlate changes in the formation of new researchers. The theoretical-methodological pressupposition is that scientific activity cannot be treated in a homogeneous way, and that there exist distinct configurations according to the disciplinary space, the institucional organization and local scientific tradition, understood as a historically rooted and socially and culturally contingent undertaking.
本文讨论了巴西人类和医学遗传学研究中心高级和初级研究人员之间的科学分工。从当代关于科学和技术逐渐交织的辩论开始——两者逐渐融合,唤起诸如技术科学之类的概念——有可能在这个特定的子领域证实,数据生产速度的提高以不同的方式给科学家带来压力:通过技术创新成本的上升和通过更复杂的分析方法的必要性。在此背景下,我分析了科学工作的专业化、概念和执行的分离以及新研究人员形成的相关变化等问题。理论方法论的假设是,科学活动不能以一种同质的方式来对待,根据学科空间、机构组织和当地科学传统,存在着不同的配置,被理解为一种历史根源和社会文化偶然的事业。
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引用次数: 2
A ideia de natureza em José Barbosa de Sá, com especial referência às plantas jose Barbosa de sa的自然概念,特别提到植物
Pub Date : 2015-09-01 DOI: 10.1590/S1678-31662015000300003
Rafael Dias da Silva Campos, C. F. M. D. Santos
This article aims to discuss philosophical elements of the work of Jose Barbosa de Sa (?-1776). We seek to analyze the author's system of botanical classification, observing the relation with the construction of analogies and likenesses, evaluating to what extent these ideas were consistent with religious conceptions. We also attempt to examine the well known eighteenth-century known debate about the vegetable reproduction and to analyse non-academic conceptions of it.
本文旨在探讨何塞·巴博萨·德·萨(?-1776)作品中的哲学元素。我们试图分析作者的植物分类体系,观察其与类比和相似构造的关系,评估这些思想在多大程度上与宗教观念相一致。我们也试图检查众所周知的18世纪关于植物繁殖的争论,并分析它的非学术概念。
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引用次数: 0
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Scientiae Studia
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