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Ultrasonic-Assisted Extraction of Phytochemicals from Eggplant Peel: Physicochemical and Antibacterial Evaluation 超声辅助提取茄子皮中植物化学物质:理化及抗菌评价
Pub Date : 2022-05-06 DOI: 10.3329/jsr.v14i2.55675
S. Sharma, A. Ojha, S. Chakkaravarthi, B. Bhattacharya
The present study aimed to prepare and characterize eggplant peel extract (EPE) with suitability for application in the food industry. EPE was prepared via ultrasound-assisted extraction method employing ethanol as an extraction solvent, then reconstituted in water. The total phenolic content, anthocyanin content, and antioxidant activity of EPE in an organic and aqueous solvent were determined. In EPE, the major anthocyanin, delphinidin-3-rutinoside, was quantified via LC-MS/MS. The agar well diffusion assay and minimum inhibitory concentration (MIC) determination method were used to analyze the antibacterial activity of EPE against Bacillus cereus, Staphylococcus aureus, Escherichia coli, and Salmonella typhimurium. There was no significant difference (p>0.05) in the total phenolic content, anthocyanin content, and antioxidant activity of EPE when reconstituted in water. The inhibition zones of EPE (at 100 mg/mL concentration) ranged from 15.6 to 21.6 mm, whereas MIC ranged from 2.34 to 4.68 mg/mL against all tested bacteria. The lower values of MIC for B. cereus and S. aureus indicated that EPE was more effective for gram-positive bacterial strains. The water-reconstituted EPE with significant antioxidant and antibacterial activity would have potential food industrial applications, like food packaging, nutraceuticals, and functional foods.
本研究旨在制备并表征适于食品工业应用的茄子皮提取物(EPE)。以乙醇为提取溶剂,采用超声辅助提取法制备EPE,然后在水中重构。测定了EPE在有机溶剂和水溶液中的总酚含量、花青素含量和抗氧化活性。用LC-MS/MS对EPE中主要花青素delphinidin-3-rutinoside进行定量分析。采用琼脂孔扩散法和最低抑菌浓度(MIC)法测定EPE对蜡样芽孢杆菌、金黄色葡萄球菌、大肠杆菌和鼠伤寒沙门菌的抑菌活性。EPE在水中复溶后,总酚含量、花青素含量和抗氧化活性均无显著差异(p>0.05)。EPE (100 mg/mL)的抑菌带范围为15.6 ~ 21.6 mm, MIC范围为2.34 ~ 4.68 mg/mL。蜡样芽孢杆菌和金黄色葡萄球菌的MIC值较低,表明EPE对革兰氏阳性菌株更有效。水重构EPE具有显著的抗氧化和抗菌活性,具有潜在的食品工业应用前景,如食品包装、营养保健品和功能食品。
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引用次数: 2
Reliability and Fault Analysis of a Stochastic Model of a Standby System with Cost Depended Repair/Replacement of Substandard Unit and Correlated Life Time 不合格部件维修/更换成本依赖和相关寿命的备用系统随机模型的可靠性和故障分析
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.57494
Sarita, P. Bhatia, S. kumar, H. K. Dhingra
The present paper deals with the reliability and fault analysis of a stochastic model for two non-identical units, in which the first unit is kept as operative and the other sub-standard one. The sub-standard unit may be repaired or may be replaced by another sub-standard unit on its failure, depending on the cost of repairing/replacement. Failure and repair times are considered correlated using bivariate point exponential distribution. Analysis of a system is done to find various reliability measures, which gives the system's effectiveness. The conclusion about these reliability measures is carried out by graphical studies. The main emphasis is on the correlation between repair time and failure time.
本文研究了两个不相同机组的随机模型的可靠性和故障分析,其中第一个机组保持工作状态,另一个机组不符合标准。根据修理/更换的费用,不符合标准的单元可以修理或更换另一个不符合标准的单元。采用双变量点指数分布将故障时间和维修时间考虑为相关关系。通过对某一系统的分析,找出了各种可靠性措施,给出了系统的有效性。通过图形化研究得出了这些可靠度测度的结论。重点讨论了维修时间与故障时间的关系。
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引用次数: 0
Synthesis, X-ray Crystallography, Hirshfeld Surface Analysis, Spectral Analysis, and Molecular Docking Studies on (E)–2–(1–(4–Fluorophenyl)Ethylidene) Hydrazine Carbothioamide (E) - 2 -(1 -(4 -氟苯基)乙基)联氨碳硫酰胺的合成、x射线晶体学、Hirshfeld表面分析、光谱分析和分子对接研究
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.57111
M. Sivasubramanian, R. Saravanan, R. Mendoza–Meroñob
Synthesis, X-ray crystallography, spectral analysis, and molecular docking analysis on (E)–2–(1–(4–fluorophenyl) ethylidene) hydrazine carbothioamide (EFEHC) are performed. Thiosemicarbazones are a class of small molecules used as anticancer therapeutics. The FT–IR and FT-Raman spectra of EFEHC have been recorded in 4000–400 and 4000–100 cm–1, respectively. The present communication deals with the quantum chemical calculations of energies, geometrical structure, and vibrational wavenumbers of EFEHC using the density functional (DFT/B3LYP) method with 6–31G (d, p) basis set. The conformational analysis gives the energy values based on the change in the position of atoms in the EFEHC molecule. Hirshfeld surface analysis (HSs) is used to discuss the evaluation of intermolecular interactions. Molecular docking analysis of the small molecule EFEHC with macromolecule HMG–CoA protein showed that this is a good molecule and is suitable for anti-cholesterol targets.
进行了(E) - 2 -(1 -(4 -氟苯基)乙基)肼碳硫酰胺(EFEHC)的合成、x射线晶体学、光谱分析和分子对接分析。硫代氨基脲是一类用于抗癌治疗的小分子。EFEHC在4000 ~ 400和4000 ~ 100 cm-1范围内分别记录了FT-IR和FT-Raman光谱。本文采用密度泛函(DFT/B3LYP)方法,在6-31G (d, p)基集上对EFEHC的能量、几何结构和振动波数进行了量子化学计算。构象分析给出了基于EFEHC分子中原子位置变化的能量值。Hirshfeld表面分析(HSs)用于讨论分子间相互作用的评价。小分子EFEHC与大分子HMG-CoA蛋白的分子对接分析表明,这是一个很好的分子,适合于抗胆固醇靶点。
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引用次数: 0
Study of Different Acid Doped Polyaniline Nanostructures and Their Electrical Conductance Properties 不同酸掺杂聚苯胺纳米结构及其导电性能的研究
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56647
R. Kamble, T. Patil, R. P. Patil
The different acid doped polyaniline (PANI) materials were prepared in situ using mineral acids like HCl, H2SO4, HNO3 and HClO4 of different concentrations in presence of 0.2 M aniline solution and 0.25 M ammonium persulfate as oxidising agent by the chemical oxidation method. The synthesized materials were studied for their physico-chemical characterizations like XRD, IR and SEM. IR studies revealed the formation of emeraldine salt in all the acid doped PANI samples. XRD of samples exhibited the partly crystalline structure of which HClO4 doped showed good crystallinity over other samples. SEM images displayed the formation of nanorods like structural agglomerates. The effect of acid dopants on their electrical conductivity was investigated by using the four probe set up technique. It was found that HClO4 doped PANI exhibited good electrical conductivity over the other acid doped samples whereas the lowest electrical conductivity was recorded for HNO3 doped PANI samples. The electrical conductivity of 1 M HClO4 doped PANI was the highest i.e.  9.1 S cm-1 among all PANI samples.
以不同浓度的HCl、H2SO4、HNO3和HClO4等无机酸为原料,以0.2 M苯胺溶液和0.25 M过硫酸铵为氧化剂,采用化学氧化法原位制备了不同酸掺杂聚苯胺(PANI)材料。对合成材料进行了XRD、IR、SEM等理化表征。红外光谱研究表明,在所有酸掺杂聚苯胺样品中都形成了翡翠盐。样品的XRD分析显示,掺杂HClO4的样品具有较好的结晶性。扫描电镜图像显示纳米棒状结构团块的形成。采用四探针设置技术研究了酸掺杂对其电导率的影响。结果表明,HClO4掺杂的聚苯胺具有较好的电导率,而HNO3掺杂的聚苯胺电导率最低。1 M HClO4掺杂聚苯胺的电导率最高,为9.1 S cm-1。
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引用次数: 0
Synthesis and in vitro Biological Studies of Copper Complexes Derived from Some Novel Hetero-Organoselanylquinoline Ligands 新型杂有机基喹啉配体铜配合物的合成及体外生物学研究
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56544
P. Moohambihai, K. Nagashri
A set of copper(II) complexes (3a-i) comprises (16E)-N-(2-phenylquinolin-4(1H)-ylidene)-3-(phenlselanyl)pyridine-2-amine (L1-L3), (16E)-2,6-dimethyl-N-(2-phenylquinolin-4(1H)-ylidene)-5-(phenlselanyl)pyrimidine-4-amine (L4-L6), 16E)-N-(2-phenylquinolin-4(1H)-ylidene)-2-(phenylselanyl)H-imidazo[1,2-α]pyridine-3-amine (L7-L9) ligands were synthesised and characterised using spectroscopic techniques. The metal-to-ligand 1:1 stoichiometry of prepared copper complexes was confirmed by mass spectra. The Cu(II) ion produces complexes with a distorted square planar, according to UV–Vis and ESR spectroscopy studies. The antioxidant activity of these complexes has been determined. The cytotoxic potential of the complexes was also investigated in vitro. The complex 3f was found to have significant cytotoxicity against MCF-7. The DNA binding characteristics of copper(II) complexes were investigated. The findings indicate that the complexes interacted with the calf thymus (CT-DNA). In addition, the complexes were tested in vitro for antimicrobial activity against three Gram-negative bacteria, three Gram-positive bacteria, and three Fungi.
合成了一组铜(II)配合物(3a-i),包括(16E)- n-(2-苯基喹啉-4(1H)-酰基)-3-(苯selanyl)吡啶-2-胺(L1-L3), (16E)-2,6-二甲基- n-(2-苯基喹啉-4(1H)-酰基)-5-(苯selanyl)嘧啶-4-胺(L4-L6), 16E)- n-(2-苯基喹啉-4(1H)-酰基)-2-(苯selanyl) h -咪唑[1,2-α]吡啶-3-胺(L7-L9)配体,并利用光谱技术进行了表征。质谱分析证实了铜配合物的金属-配体1:1的化学计量。根据紫外-可见和ESR光谱研究,Cu(II)离子产生具有扭曲方形平面的配合物。测定了这些配合物的抗氧化活性。体外研究了该复合物的细胞毒性潜能。发现复合物3f对MCF-7具有显著的细胞毒性。研究了铜(II)配合物的DNA结合特性。研究结果表明,这些复合物与小牛胸腺(CT-DNA)相互作用。此外,还对三种革兰氏阴性菌、三种革兰氏阳性菌和三种真菌进行了体外抗菌活性测试。
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引用次数: 0
On Certain Quadruple Fixed Points of Integral Type Contraction Mappings in G-Metric Spaces and its Applications g -度量空间中积分型收缩映射的若干四重不动点及其应用
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56189
B. Rao, L. V. Kumar, C. Maheswari, S. M. Shaw
In this paper, the existence of common quadruple fixed point results for integral type contraction of two mappings in G-metric spaces is established. Some interesting consequences of our results are achieved. Moreover, we give an illustration that presents the applicability of the achieved results.
本文建立了g -度量空间中两个映射的积分型收缩的公共四重不动点结果的存在性。我们的结果产生了一些有趣的结果。此外,我们给出了一个例子来说明所取得的结果的适用性。
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引用次数: 0
Modeling of the Peristaltic Lithogeic Bile Flow in the Calculus Duct Under the Influence of Heat Transfer with Slip Boundary Conditions 滑移边界条件下换热影响下结石管内岩石胆汁蠕动流动的模拟
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.55882
T. Rawat, S. Kumari, S. Singh
This paper deals with a mathematical model that represents non-Newtonian bile flow through a calculus duct under the influence of heat transfer with wall slip conditions. The peristaltic flow of bile is characterized by a generalized Carreau's model. An ordinate transformation is initiated to map the cosine geometry of the stone into a rectangular grid. It allows evaluation velocity, pressure distribution, flow rate, and reflux occurrence conditions, adopting the perturbation technique, the analytical solution obtained under various parameters, such as Knudsen number, amplitude ratio, Grashof number, Weissenberg number, and power index. These mathematical expressions are analyzed by plotting the graph in MATLAB R2018b software and observed that the axial velocity and the pressure gradient are strongly affected by heat and wall slip parameters.
本文讨论了在壁面滑移条件下传热影响下非牛顿胆汁流过结石管的数学模型。胆汁的蠕动流动是用广义的卡鲁模型来描述的。开始进行纵坐标变换,将石头的余弦几何映射到矩形网格中。它可以评价流速、压力分布、流量和回流发生条件,采用摄动技术,得到各种参数下的解析解,如Knudsen数、振幅比、Grashof数、Weissenberg数和功率指数。在MATLAB R2018b软件中对这些数学表达式进行了分析,并观察到轴向速度和压力梯度受热量和壁面滑移参数的强烈影响。
{"title":"Modeling of the Peristaltic Lithogeic Bile Flow in the Calculus Duct Under the Influence of Heat Transfer with Slip Boundary Conditions","authors":"T. Rawat, S. Kumari, S. Singh","doi":"10.3329/jsr.v14i2.55882","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.55882","url":null,"abstract":"This paper deals with a mathematical model that represents non-Newtonian bile flow through a calculus duct under the influence of heat transfer with wall slip conditions. The peristaltic flow of bile is characterized by a generalized Carreau's model. An ordinate transformation is initiated to map the cosine geometry of the stone into a rectangular grid. It allows evaluation velocity, pressure distribution, flow rate, and reflux occurrence conditions, adopting the perturbation technique, the analytical solution obtained under various parameters, such as Knudsen number, amplitude ratio, Grashof number, Weissenberg number, and power index. These mathematical expressions are analyzed by plotting the graph in MATLAB R2018b software and observed that the axial velocity and the pressure gradient are strongly affected by heat and wall slip parameters.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88953945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Phenolic Contents and Anti-lipooxygenase Activity of the Methanolic Extracts from Durio zibethinus Murr 紫豆醇提物总酚含量及抗脂氧化酶活性研究
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56287
S. Adeniyi, G. Olatunji, O. Oguntoye
Durio zibethinus parts (leaves, stem bark, and root) used to treat malaria fever, vermifuge, diabetes, jaundice, inflammation, and oxidative stress management prompted the investigation of their total phenolic contents and anti-lipooxygenase activities. The total phenolic concentration of D. zibethinus parts was determined spectrophotometrically after collection and extraction. The anti-inflammatory activity was estimated using a lipooxygenase assay. Total phenolic content measured in gallic acid equivalent (GAE) gave the highest levels of 6.88 ± 1.54, 23.32 ± 1.73, and 29.00 ± 3.43 mg GAE/g sample weight leaves stem bark, and root extracts, respectively. The plant extracts showed lower anti- lipooxygenase activity in leaves (IC50 µg/mL- 1.464) and stem bark (IC50 µg/mL- 1.203), but had significant activity in root (IC50 µg/mL- 1.400) compared to standard indomethacin (IC50 µg/mL- 1.660). The plant extract's declining order of anti- lipooxygenase activity follows the same trend with the phenolic contents, indicating that the extract's magnitude of anti- lipooxygenase activity is comparable with the quantity of phenolic compounds present in the extracts. Hence, the D. zibethinus extracts are a potential candidate for a plant-derived anti-inflammatory agent.
紫豆部分(叶、茎、皮和根)用于治疗疟疾热、寄生虫病、糖尿病、黄疸、炎症和氧化应激管理,促使人们对其总酚含量和抗脂氧化酶活性进行研究。收集提取后,采用分光光度法测定了紫荆各部位总酚的含量。用脂氧化酶测定法估计其抗炎活性。未食子酸当量(GAE)中总酚含量最高,分别为6.88±1.54、23.32±1.73和29.00±3.43 mg GAE/g样品质量。与标准吲哚美辛(IC50µg/mL- 1.660)相比,该植物提取物在叶片(IC50µg/mL- 1.464)和茎皮(IC50µg/mL- 1.203)中的抗脂氧化酶活性较低,但在根(IC50µg/mL- 1.400)中的抗脂氧化酶活性显著。植物提取物抗脂氧化酶活性的下降顺序与酚类化合物含量的下降趋势一致,表明提取物抗脂氧化酶活性的强弱与酚类化合物含量相当。因此,zibethinus提取物是一种潜在的候选植物源抗炎剂。
{"title":"Total Phenolic Contents and Anti-lipooxygenase Activity of the Methanolic Extracts from Durio zibethinus Murr","authors":"S. Adeniyi, G. Olatunji, O. Oguntoye","doi":"10.3329/jsr.v14i2.56287","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56287","url":null,"abstract":"Durio zibethinus parts (leaves, stem bark, and root) used to treat malaria fever, vermifuge, diabetes, jaundice, inflammation, and oxidative stress management prompted the investigation of their total phenolic contents and anti-lipooxygenase activities. The total phenolic concentration of D. zibethinus parts was determined spectrophotometrically after collection and extraction. The anti-inflammatory activity was estimated using a lipooxygenase assay. Total phenolic content measured in gallic acid equivalent (GAE) gave the highest levels of 6.88 ± 1.54, 23.32 ± 1.73, and 29.00 ± 3.43 mg GAE/g sample weight leaves stem bark, and root extracts, respectively. The plant extracts showed lower anti- lipooxygenase activity in leaves (IC50 µg/mL- 1.464) and stem bark (IC50 µg/mL- 1.203), but had significant activity in root (IC50 µg/mL- 1.400) compared to standard indomethacin (IC50 µg/mL- 1.660). The plant extract's declining order of anti- lipooxygenase activity follows the same trend with the phenolic contents, indicating that the extract's magnitude of anti- lipooxygenase activity is comparable with the quantity of phenolic compounds present in the extracts. Hence, the D. zibethinus extracts are a potential candidate for a plant-derived anti-inflammatory agent.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87134273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video Summarization Using Deep Learning for Cricket Highlights Generation 使用深度学习生成板球集锦的视频摘要
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56856
D. Gaikwad, S. Sarap, D. Dhande
Recently, video surveillance technology has grown pervasive in many aspects of our lives. Automatic video monitoring produces massive amounts of data that need human examination at some point. The primary emphasis is on reducing storage usage by compressing or eliminating superfluous frames without sacrificing real information. The current effort seeks to close the growing gap between the amounts of real data and the volume. Searching through key events in large video collections is time-consuming and tedious. In this paper, smart surveillance for various applications by using video summarization has been presented. A method for generating highlights has presented which pre-processes extracted Video Frames. Convolutional Neural Networks are then used to evaluate these highlighted frames. The proposed technique extracts and calculates characteristics utilized to generate summary movies. For training deep neural networks, cricket datasets have been used. Experimental results show that the proposed solution attains improved results than other advanced summarization methodologies. Experimental results show that the proposed video summarization method consistently generates high-quality reviews for all types of videos. The proposed video summarization method is easy to use, and it can also help extract highlights of cricket games with high accuracy.
近年来,视频监控技术已经在我们生活的方方面面变得无处不在。自动视频监控会产生大量的数据,在某些时候需要人工检查。主要的重点是在不牺牲真实信息的情况下,通过压缩或消除多余的帧来减少存储使用。目前的努力旨在缩小实际数据量与数据量之间日益扩大的差距。在大型视频集合中搜索关键事件既耗时又乏味。本文介绍了基于视频摘要的智能监控技术在各种应用中的应用。提出了一种通过预处理提取视频帧来生成高光的方法。然后使用卷积神经网络来评估这些突出显示的帧。该技术提取并计算用于生成摘要电影的特征。为了训练深度神经网络,已经使用了板球数据集。实验结果表明,与其他先进的摘要方法相比,该方法取得了更好的效果。实验结果表明,所提出的视频摘要方法对所有类型的视频都能产生高质量的评论。所提出的视频摘要方法易于使用,并且能够以较高的准确率提取板球比赛的亮点。
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引用次数: 0
Classification of Hot Jupiter Population through Statistical Framework 基于统计框架的热木星人口分类
Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56497
S. Mondal
The recent trend in the discovery of a range of exoplanets opens up a door to evaluate their origin and classification under the light of different planetary attributes. This paper enthusiastically focused on a typical branch of exoplanets, hot Jupiter, and several planetary characteristics were observed to frame the population into substantive categories. In this paper, a statistical framework was also established to understand different planetary formation processes for hot Jupiters. Finally, the relevance of hot Jupiters in search of habitable planets is also discussed briefly.
最近一系列系外行星的发现趋势为根据不同的行星属性来评估它们的起源和分类打开了一扇门。这篇论文热情地关注了系外行星的一个典型分支——热木星,并观察了几个行星的特征,将其划分为实质性的类别。本文还建立了一个统计框架,以了解热木星的不同行星形成过程。最后,还简要讨论了热木星与寻找可居住行星的相关性。
{"title":"Classification of Hot Jupiter Population through Statistical Framework","authors":"S. Mondal","doi":"10.3329/jsr.v14i2.56497","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56497","url":null,"abstract":"The recent trend in the discovery of a range of exoplanets opens up a door to evaluate their origin and classification under the light of different planetary attributes. This paper enthusiastically focused on a typical branch of exoplanets, hot Jupiter, and several planetary characteristics were observed to frame the population into substantive categories. In this paper, a statistical framework was also established to understand different planetary formation processes for hot Jupiters. Finally, the relevance of hot Jupiters in search of habitable planets is also discussed briefly.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87766534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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JOURNAL OF SCIENTIFIC RESEARCH
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