Right to know is a right defined and considered in human rights, regarded by human rights communities more than ever in all topics of human rights. This topic has actually penetrated into medical system as a continuous objective for Ministry of Health in our country. In patient rights charter of Ministry of Health, right of patient to know is mentioned which is adopted from this right. Health authorities believe that patients must know about all diagnostic and treatment methods, power and weak points of each method and potential complications, disease diagnosis, prognosis and its consequences as well as all information affecting decision making. Finally with complete information they communicate their consent to medical system and physicians for treatment. Based on research findings, right of patient to know has been considered in the framework of patient rights charter in Health System Development Plan and it has been attempted to consider patient rights charter more than ever.
{"title":"Right of patient to know with an approach to Health System Development Plan","authors":"H. Babaei, Fardin Hosseinpanahi","doi":"10.24896/JRMDS.V4I3.201","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I3.201","url":null,"abstract":"Right to know is a right defined and considered in human rights, regarded by human rights communities more than ever in all topics of human rights. This topic has actually penetrated into medical system as a continuous objective for Ministry of Health in our country. In patient rights charter of Ministry of Health, right of patient to know is mentioned which is adopted from this right. Health authorities believe that patients must know about all diagnostic and treatment methods, power and weak points of each method and potential complications, disease diagnosis, prognosis and its consequences as well as all information affecting decision making. Finally with complete information they communicate their consent to medical system and physicians for treatment. Based on research findings, right of patient to know has been considered in the framework of patient rights charter in Health System Development Plan and it has been attempted to consider patient rights charter more than ever.","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"178-182"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69149410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Low level laser is a type of laser with various bio stimulatory effects; Potential effects of laser in accelerating bone regeneration and consequently facilitating tooth movement have been considered widely in orthodontics. Aims & Objectives: Aim of this study was to assess the effects of Low level laser on the velocity of mandibular first molar protraction in orthodontic patients. Materials and Methods: Total 28 young adult patients (14 females and 14 males; age range 16-25) requiring extraction of mandibular second premolars were selected and molar protraction was carried out with T-loop on a rectangular Stainless Steel wire. In each patient one side was selected by random to irradiate with low level laser and other side with placebo. Laser regimen was applied at 0, 1 and 2 days and at the end of first, second and third months. Tooth movement was measured on prepared models at the end of first, second and third month. Results: We found 1.3 fold increases in rate of tooth movement in the irradiated group (p=0.000) than non-irradiated group. Conclusion: Based on our findings, Low level laser accelerates tooth movement and consequently reduces treatment time. Key word: Low level laser; Tooth movement; First molar, Irradiation; Protraction
{"title":"Evaluating the effect of low energy laser irradiation on the rate of mandibular molar protraction in orthodontic patients","authors":"Sepideh Gavareshki, P. Salehi, S. Torkan","doi":"10.24896/JRMDS.V4I3.211","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I3.211","url":null,"abstract":"Background: Low level laser is a type of laser with various bio stimulatory effects; Potential effects of laser in accelerating bone regeneration and consequently facilitating tooth movement have been considered widely in orthodontics. Aims & Objectives: Aim of this study was to assess the effects of Low level laser on the velocity of mandibular first molar protraction in orthodontic patients. Materials and Methods: Total 28 young adult patients (14 females and 14 males; age range 16-25) requiring extraction of mandibular second premolars were selected and molar protraction was carried out with T-loop on a rectangular Stainless Steel wire. In each patient one side was selected by random to irradiate with low level laser and other side with placebo. Laser regimen was applied at 0, 1 and 2 days and at the end of first, second and third months. Tooth movement was measured on prepared models at the end of first, second and third month. Results: We found 1.3 fold increases in rate of tooth movement in the irradiated group (p=0.000) than non-irradiated group. Conclusion: Based on our findings, Low level laser accelerates tooth movement and consequently reduces treatment time. Key word: Low level laser; Tooth movement; First molar, Irradiation; Protraction","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"228-232"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69150022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Evaluation is one of the most important stages of education system. Student exams may be used both for student assessment and program evaluation. Given the significance of general medicine exams, the present study systematically reviews studies conducted on these exams in Iran in 2016.Methods : Available documents weresystematically reviewed and their information was collected. Using documents available in scientific databases suchas IranMedex, SID, Magiran, Medlib, PubMed, Google Scholar, ERIC by appropriate keywords (doctor, generalpractitioner, student, graduate, trainee, intern, exam, general sciences, pre-internship, skill and medical), 59 studies conducted on general medicine exams until March 2015 were extracted; of these studies, 10 studies which wereavailable in full text and met the least research quality were selected for the review. Results: Out of 10 studiesreviewed, 7 studies evaluated the effective factors on results of general medicine exams and 3 studies analyzed theresults of these exams. Meanwhile, results of those 7 studies showed that low GPA, delay in passing the basicsciences and age at the time of admission to the university are effective factors on results of exams. Results of threestudies analyzing exams showed that genetics and radiology gained the highest and parasitology, orthopedics andphysiology gained the lowest average percentage of scaled relative ratings. In analysis of 40 exams during a 20-yearperiod, 65.8% students were passed the exams in the first trial. However, 99.6% of participants continued their education after few trials. Conclusion: The factors such as length of stay in medical school and grand point averageof students are predicating comprehensive exam results in all the reviewed studies. Therefore, these factors can beconsidered as effective factors on results of general medicine exams. Also the results may support the importance ofnational comprehensive exams as a reliable tool in fostering quality in education. Keywords: exam, basic sciences, pre-internship, general medicine
{"title":"A Systematic Review of Studies on General Medicine Comprehensive Exams in Iran","authors":"T. Changiz, F. Asgari, N. Yamani","doi":"10.24896/JRMDS.V4I4.232","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I4.232","url":null,"abstract":"Introduction: Evaluation is one of the most important stages of education system. Student exams may be used both for student assessment and program evaluation. Given the significance of general medicine exams, the present study systematically reviews studies conducted on these exams in Iran in 2016.Methods : Available documents weresystematically reviewed and their information was collected. Using documents available in scientific databases suchas IranMedex, SID, Magiran, Medlib, PubMed, Google Scholar, ERIC by appropriate keywords (doctor, generalpractitioner, student, graduate, trainee, intern, exam, general sciences, pre-internship, skill and medical), 59 studies conducted on general medicine exams until March 2015 were extracted; of these studies, 10 studies which wereavailable in full text and met the least research quality were selected for the review. Results: Out of 10 studiesreviewed, 7 studies evaluated the effective factors on results of general medicine exams and 3 studies analyzed theresults of these exams. Meanwhile, results of those 7 studies showed that low GPA, delay in passing the basicsciences and age at the time of admission to the university are effective factors on results of exams. Results of threestudies analyzing exams showed that genetics and radiology gained the highest and parasitology, orthopedics andphysiology gained the lowest average percentage of scaled relative ratings. In analysis of 40 exams during a 20-yearperiod, 65.8% students were passed the exams in the first trial. However, 99.6% of participants continued their education after few trials. Conclusion: The factors such as length of stay in medical school and grand point averageof students are predicating comprehensive exam results in all the reviewed studies. Therefore, these factors can beconsidered as effective factors on results of general medicine exams. Also the results may support the importance ofnational comprehensive exams as a reliable tool in fostering quality in education. Keywords: exam, basic sciences, pre-internship, general medicine","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"38-44"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69150604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Karmakar, Saugat Banerjee, Amiya Das, A. Dasgupta, Mahul Mukhopadhyay
Background: Hypertension, a major chronic lifestyle disease is most prevalent non communicable disease inIndia. Blood pressure (BP) measurements in the community are generally performed with a mercurysphygmomanometer. However, it is the common teaching that average of at least three readings of bloodpressure measurement is considered to be the gold-standard method. How far this is true has been determinedin this study with the Aim: To find out the prevalence of hypertension and compare the one reading of bloodpressure taken by mercury sphygmomanometer with average of three such readings. Materials andMethods:This cross-sectional study was conducted from January-March 2015 among 160 adults of Chetla slum, Kolkatachosen through a two stage sample design. ubjects included -Male: 39.4%; Female: 60.6%. Data was collectedby interview and blood pressure measurements. Comparison was made between the first reading and theaverage of three readings of BP taken by mercury sphygmomanometer. Result: The overall prevalence ofhypertension was found to be 30 % (48). Strength of agreement between first reading of Blood Pressure with thatof average reading was excellent, with kappa=0.940. Conclusion: Though the average of three blood pressurereadings according to Standard operation Procedure is considered ideal for accurate Blood Pressuremeasurement it may not always be feasible to undertake such a practice especially at community level. Thisstudy observes that single reading can safely be considered for Blood Pressure measurement instead of averageof three readings. Key words: Blood Pressure measurement, One reading, Average of three readings, Mercury sphygmomanometer, Slum.
{"title":"A study on hypertension and comparability between one reading and average of three readings of blood pressure by mercury sphygmomanometer among adults in a slum of Kolkata","authors":"N. Karmakar, Saugat Banerjee, Amiya Das, A. Dasgupta, Mahul Mukhopadhyay","doi":"10.24896/JRMDS.V4I4.233","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I4.233","url":null,"abstract":"Background: Hypertension, a major chronic lifestyle disease is most prevalent non communicable disease inIndia. Blood pressure (BP) measurements in the community are generally performed with a mercurysphygmomanometer. However, it is the common teaching that average of at least three readings of bloodpressure measurement is considered to be the gold-standard method. How far this is true has been determinedin this study with the Aim: To find out the prevalence of hypertension and compare the one reading of bloodpressure taken by mercury sphygmomanometer with average of three such readings. Materials andMethods:This cross-sectional study was conducted from January-March 2015 among 160 adults of Chetla slum, Kolkatachosen through a two stage sample design. ubjects included -Male: 39.4%; Female: 60.6%. Data was collectedby interview and blood pressure measurements. Comparison was made between the first reading and theaverage of three readings of BP taken by mercury sphygmomanometer. Result: The overall prevalence ofhypertension was found to be 30 % (48). Strength of agreement between first reading of Blood Pressure with thatof average reading was excellent, with kappa=0.940. Conclusion: Though the average of three blood pressurereadings according to Standard operation Procedure is considered ideal for accurate Blood Pressuremeasurement it may not always be feasible to undertake such a practice especially at community level. Thisstudy observes that single reading can safely be considered for Blood Pressure measurement instead of averageof three readings. Key words: Blood Pressure measurement, One reading, Average of three readings, Mercury sphygmomanometer, Slum.","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"45-50"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69151109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rushil Shah, C. Venkatesh, P. Patel, Nikan Makadia
Medical emergencies are the detrimental medical episodes that may be apparent in dental settings. Diligent understanding of the emergencies is absolutely necessary for all dental surgeons and auxiliaries. Appropriate diagnosis and subsequent care play a key role in the management of medical emergencies in dental clinic. The utmost purpose of this article is to shed light on the typical medical emergencies in dental setting and their subsequent management.
{"title":"Medical emergencies in dental clinic","authors":"Rushil Shah, C. Venkatesh, P. Patel, Nikan Makadia","doi":"10.24896/JRMDS.V4I1.166","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I1.166","url":null,"abstract":"Medical emergencies are the detrimental medical episodes that may be apparent in dental settings. Diligent understanding of the emergencies is absolutely necessary for all dental surgeons and auxiliaries. Appropriate diagnosis and subsequent care play a key role in the management of medical emergencies in dental clinic. The utmost purpose of this article is to shed light on the typical medical emergencies in dental setting and their subsequent management.","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"18-20"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69147357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anshul Shah, Aditi Kumbhalwar, P. Ragasree, Sonali Patel, A. Pala, Neetika Thukral
Trigeminal neuralgia is a chronic pain disorder affecting the trigeminal nerve which usually worsens with passage of time. It is an episodic pain syndrome which has been fairly responsive to medical & surgical treatment modalities. It is a pathology characterized by paroxysmal pain so severe and sudden almost like an electric shock, which lasts from a range of very few seconds to a maximum of two minutes. The article is focused on different treatment modalities and their subsequent prognosis. Key words: Trigeminal Neuralgia, Oro-Facial Pain, Treatment
{"title":"Variegated treatment modalities for trigeminal neuralgia","authors":"Anshul Shah, Aditi Kumbhalwar, P. Ragasree, Sonali Patel, A. Pala, Neetika Thukral","doi":"10.24896/JRMDS.V4I1.167","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I1.167","url":null,"abstract":"Trigeminal neuralgia is a chronic pain disorder affecting the trigeminal nerve which usually worsens with passage of time. It is an episodic pain syndrome which has been fairly responsive to medical & surgical treatment modalities. It is a pathology characterized by paroxysmal pain so severe and sudden almost like an electric shock, which lasts from a range of very few seconds to a maximum of two minutes. The article is focused on different treatment modalities and their subsequent prognosis. Key words: Trigeminal Neuralgia, Oro-Facial Pain, Treatment","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"21-24"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69147383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Brucellosis is a public health problem in the world. Several diagnostic tests have been proposedfor the diagnosis of brucellosis, including Standard Agglutination Test (SAT) and Coombs anti-brucella tests.However these tests does not discriminate the immunoglobulin classes of this condition. The aim of current studywas to explore the sensitivity and specificity of Immunosorbent Assay (ELISA) IgG and IgM tests in patients withBrucella bacteremia. Material and Methods: Thirty-one patients with clinical features suggestive of Brucellosisand were positive blood cultures for Brucella species, were enrolled. Brucella enzyme linked immunosorbentassay test determining the Brucella specific IgG and IgM, antibodies was utilized for the diagnosis of Brucellosis. Results: 31 patients including 18male (52.2%) and 13 female (47.8%) were used for IgG and IgM tests. 23 subjects had a history of dairy consumption. In 6subjects (20.3%) the history of brucellosis in family waspositive.2 subjects had contact with cattles. Our data showed that the sensitivity, specificity, PVP and PVN ofIgMwere100, 72.7,100 and 83.3%, while these values in IgG test were 100, 63.3, 86.9, 100% respectively. Conclusion: Our findings further confirmed that diagnostic value of ELISA based IgG and IgM with highsensitivity, compared to agglutination test, suggesting its value as a simple, rapid, sensitive and reliable methodfor the diagnosis of brucellosis. Keywords: ELISA, IgG, IgM, Brucellosis
{"title":"Sensitivity and specificity of Enzyme-Linked Immunosorbent Assays in Brucellosis","authors":"A. Sharif, Z. Soleimani, Kataneh Khamooshi","doi":"10.24896/JRMDS.V4I4.228","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I4.228","url":null,"abstract":"Background: Brucellosis is a public health problem in the world. Several diagnostic tests have been proposedfor the diagnosis of brucellosis, including Standard Agglutination Test (SAT) and Coombs anti-brucella tests.However these tests does not discriminate the immunoglobulin classes of this condition. The aim of current studywas to explore the sensitivity and specificity of Immunosorbent Assay (ELISA) IgG and IgM tests in patients withBrucella bacteremia. Material and Methods: Thirty-one patients with clinical features suggestive of Brucellosisand were positive blood cultures for Brucella species, were enrolled. Brucella enzyme linked immunosorbentassay test determining the Brucella specific IgG and IgM, antibodies was utilized for the diagnosis of Brucellosis. Results: 31 patients including 18male (52.2%) and 13 female (47.8%) were used for IgG and IgM tests. 23 subjects had a history of dairy consumption. In 6subjects (20.3%) the history of brucellosis in family waspositive.2 subjects had contact with cattles. Our data showed that the sensitivity, specificity, PVP and PVN ofIgMwere100, 72.7,100 and 83.3%, while these values in IgG test were 100, 63.3, 86.9, 100% respectively. Conclusion: Our findings further confirmed that diagnostic value of ELISA based IgG and IgM with highsensitivity, compared to agglutination test, suggesting its value as a simple, rapid, sensitive and reliable methodfor the diagnosis of brucellosis. Keywords: ELISA, IgG, IgM, Brucellosis","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"17-20"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69150345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: To enhance and possibly overcome limits in the biological potential, several research approaches have assessed the possible benefits of GTR modulation by root surface conditioning agents. Objective: A Comparison of bio resorbable membrane alone or in Combination with tetracycline root conditioning in treating intrabony defects. Material & Methods: Study design: A case-control study. Setting: Department of Periodontics, Subharti Dental College, Meerut Uttar Pradesh, India. Participants: 20 patients Sampling: Random sampling. Statistical Analysis: Data entry and statistical analysis were carried out using SPSS 10. Unpaired student “t”test was applied Results: On comparing the values of pocket depth (PD) and depth of defect area (INFRA I) Group A and Group B patients at baseline and 6 months, a decrease in the PD and INFRA I after the treatment were observed. Intergroup comparison of the treatment outcomes on PD and INFRA I revealed no statistically significant difference between the two groups. Conclusion: It was concluded that combining GTR technique with the TTC-HCl root conditioning does not improve the results in terms of clinical and radiographic outcomes. Keywords: Guided tissue regeneration, Bioresorbable membranes, Tetracycline root conditioning
{"title":"A Comparison of bioresorbable membrane alone or in Combination with tetracycline root conditioning in treating intrabony defects","authors":"R. Khan, M. H. Khan","doi":"10.24896/JRMDS.V4I3.215","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I3.215","url":null,"abstract":"Background: To enhance and possibly overcome limits in the biological potential, several research approaches have assessed the possible benefits of GTR modulation by root surface conditioning agents. Objective: A Comparison of bio resorbable membrane alone or in Combination with tetracycline root conditioning in treating intrabony defects. Material & Methods: Study design: A case-control study. Setting: Department of Periodontics, Subharti Dental College, Meerut Uttar Pradesh, India. Participants: 20 patients Sampling: Random sampling. Statistical Analysis: Data entry and statistical analysis were carried out using SPSS 10. Unpaired student “t”test was applied Results: On comparing the values of pocket depth (PD) and depth of defect area (INFRA I) Group A and Group B patients at baseline and 6 months, a decrease in the PD and INFRA I after the treatment were observed. Intergroup comparison of the treatment outcomes on PD and INFRA I revealed no statistically significant difference between the two groups. Conclusion: It was concluded that combining GTR technique with the TTC-HCl root conditioning does not improve the results in terms of clinical and radiographic outcomes. Keywords: Guided tissue regeneration, Bioresorbable membranes, Tetracycline root conditioning","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"248-252"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69150671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Latha, A. Suchetha, D. Mundinamane, Apoorva Sm, Divya B. Bhatt, V. Mp
Inflammation comprises a series of events that leads to a host response against trauma and microbial invasion, resulting in liquefaction of surrounding tissues to prevent microbial metastasis, and eventually to healing of injured tissue compartments. Thus, by definition, the host response involves not only the mechanisms of defence but also processes of repair of damage that occurs by the direct effect of invaders or trauma or host systems. Periodontal diseases are inflammatory processes in which microbial etiologic factors induce a series of host responses that mediate an inflammatory cascade of events in an attempt to protect and heal the periodontal tissues. The adjunctive use of host modulation therapy can enhance therapeutic responses, slow the progression of the disease, and allow for more predictable management of patients, particularly in those patients at increased risk caused by factors beyond the reach of conventional therapeutic approaches. Key words: Host modulation, NSAIDs, Bisphosphonates, immune-inflammatory response, MMPs
{"title":"Host modulation therapy- An innovative paradigm in dentistry","authors":"G. Latha, A. Suchetha, D. Mundinamane, Apoorva Sm, Divya B. Bhatt, V. Mp","doi":"10.24896/JRMDS.V4I1.165","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I1.165","url":null,"abstract":"Inflammation comprises a series of events that leads to a host response against trauma and microbial invasion, resulting in liquefaction of surrounding tissues to prevent microbial metastasis, and eventually to healing of injured tissue compartments. Thus, by definition, the host response involves not only the mechanisms of defence but also processes of repair of damage that occurs by the direct effect of invaders or trauma or host systems. Periodontal diseases are inflammatory processes in which microbial etiologic factors induce a series of host responses that mediate an inflammatory cascade of events in an attempt to protect and heal the periodontal tissues. The adjunctive use of host modulation therapy can enhance therapeutic responses, slow the progression of the disease, and allow for more predictable management of patients, particularly in those patients at increased risk caused by factors beyond the reach of conventional therapeutic approaches. Key words: Host modulation, NSAIDs, Bisphosphonates, immune-inflammatory response, MMPs","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69147713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Tabatabaei, R. Razzaghi, Z. Soleimani, S. Nouri
Background: Hearing loss is considered as one of the complications in diabetic patients. However, studies reported conflicting results on the relationship between diabetes and hearing loss. Objectives: This study aimed to investigateand compare the prevalence of hearing loss in patients with diabetes mellitus and a group of non-diabetic people. Materials and Methods: This study was conducted on 80 patients with diabetes and 80 non-diabetic subjects.Subjects in the case group were selected among the diabetic patients registered in the diabetes centers of Isfahanprovince. Subjects in the control group were selected among non-diabetic individuals referring to the blood bank todonate blood. The instrument used for data collection included of questions on the subjects demographics and a special form for recording the results of the subjects’ laboratory examinations including HbA1c, TSH, Cr and theresult of the audiometric examinations. Data analysis was performed using descriptive statistics, chi-square test andt-test or nonparametric equivalents. Results: Compared with non-diabetic subjects, hearing loss in sounds with high frequencies was more common in patients with diabetes (P value = 0.001), the mean creatinine was significantly different in diabetic patients with and without hearing loss at noise frequencies of 4 KHz and 8 KHz (P value< 0.05). However, hemoglobin A1C, duration of diabetes and BMI were not significantly associated with hearing loss. Conclusion: Hearing impairment in high frequency sounds is more common in diabetics than healthy individuals.The severity of hearing loss in patients with diabetes is also associated with the levels of creatinine. Keywords: Hearing Loss, Diabetes mellitus, Audiometry
{"title":"The risk factors of hearing loss in diabetes mellitus","authors":"F. Tabatabaei, R. Razzaghi, Z. Soleimani, S. Nouri","doi":"10.24896/JRMDS.V4I4.234","DOIUrl":"https://doi.org/10.24896/JRMDS.V4I4.234","url":null,"abstract":"Background: Hearing loss is considered as one of the complications in diabetic patients. However, studies reported conflicting results on the relationship between diabetes and hearing loss. Objectives: This study aimed to investigateand compare the prevalence of hearing loss in patients with diabetes mellitus and a group of non-diabetic people. Materials and Methods: This study was conducted on 80 patients with diabetes and 80 non-diabetic subjects.Subjects in the case group were selected among the diabetic patients registered in the diabetes centers of Isfahanprovince. Subjects in the control group were selected among non-diabetic individuals referring to the blood bank todonate blood. The instrument used for data collection included of questions on the subjects demographics and a special form for recording the results of the subjects’ laboratory examinations including HbA1c, TSH, Cr and theresult of the audiometric examinations. Data analysis was performed using descriptive statistics, chi-square test andt-test or nonparametric equivalents. Results: Compared with non-diabetic subjects, hearing loss in sounds with high frequencies was more common in patients with diabetes (P value = 0.001), the mean creatinine was significantly different in diabetic patients with and without hearing loss at noise frequencies of 4 KHz and 8 KHz (P value< 0.05). However, hemoglobin A1C, duration of diabetes and BMI were not significantly associated with hearing loss. Conclusion: Hearing impairment in high frequency sounds is more common in diabetics than healthy individuals.The severity of hearing loss in patients with diabetes is also associated with the levels of creatinine. Keywords: Hearing Loss, Diabetes mellitus, Audiometry","PeriodicalId":17001,"journal":{"name":"Journal of Research in Medical and Dental Science","volume":"4 1","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69151168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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