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Study of application of Non Invasive Ventilation in patients of severe pneumonia and acute respiratory failure caused by novel influenza A H1N1 virus 无创通气在新型甲型H1N1流感病毒所致重症肺炎急性呼吸衰竭患者中的应用研究
Pub Date : 2016-01-01 DOI: 10.24896/jrmds.v4i2.182
Rahul M Gambhir, M. Rathod
Background: Respiratory system is the most common organ system affected in patients of H1N1influenza. Many patients requires mechanical ventilation for treatment as they develop ALI/ARDS due to primary viral or secondary bacterial pneumonia. In resource poor countries like us, providing ICU ventilator to all patients can produce a difficult task for health care system. Noninvasive ventilation can be an option provided appropriate patients are chooses at right stage of disease-probably in early stage of acute hypoxic respiratory failure. Aim: (1) To identify the patients suitable for non-invasive ventilation in patients of swine flu with signs of respiratory failure (2) To study outcome of NIV in these patients with aim to identify factors for the so called “late failure of NIV”. Materials and Methods: This study is meant to analyze data from patients of Novel H1N1 influenza patients admitted to swine flu isolation ward during January to December 2015 at PDU Hospital, Rajkot. From 650 patients admitted as suspected case, 283 were confirmed by RTPCR. Among 84 patients who were offered NIV 43 died during course of treatment. It is a retrospective study to analyze the patients who remains stable on NIV for at least 24 hrs. There were 66 such patients. Results: Out of 66 patients studied, 40 successfully treated with NIV. After initial 24 hrs factors which were statistically significantly associated with NIV late failure were-pregnancy (including postpartum period), tachycardia on admission and high total count during course of treatment (suggesting developing bacterial pneumonia). Conclusion: NIV can be used in selected patients of viral pneumonia. In pregnant or postpartum patients NIV should be used with caution. Signs of developing of bacterial pneumonia and MODS herald the chances of NIV failure. Co morbidities are not a strong predictor for NIV failure. Avoiding intubation can decrease complications particularly in immunocompromised patients. Use of steroid does not have significant effect on respiratory function improvement. Key words: H1N1 influenza A infection, severe pneumonia, NIV late failure
背景:呼吸系统是甲型h1n1流感患者最常见的器官系统。许多患者由于原发性病毒性或继发性细菌性肺炎而发生ALI/ARDS,需要机械通气治疗。在像我们这样资源贫乏的国家,为所有患者提供ICU呼吸机对卫生保健系统来说是一项艰巨的任务。无创通气可以是一种选择,只要在疾病的正确阶段选择合适的患者-可能在急性缺氧呼吸衰竭的早期。目的:(1)确定有呼吸衰竭体征的猪流感患者中适合进行无创通气的患者(2)研究这些患者的无创通气转归,旨在找出所谓“晚期无创通气失败”的因素。材料与方法:本研究旨在分析2015年1 - 12月Rajkot市PDU医院猪流感隔离病房收治的新型H1N1流感患者的数据。650例疑似病例中,283例经RTPCR确诊。84例接受NIV治疗的患者中,43例在治疗过程中死亡。这是一项回顾性研究,分析在NIV中保持稳定至少24小时的患者。共有66例患者。结果:66例患者中,40例成功治疗。在最初24小时后,与NIV晚期失败有统计学意义相关的因素是妊娠(包括产后)、入院时心动过速和治疗期间总计数高(提示发生细菌性肺炎)。结论:NIV可用于选定的病毒性肺炎患者。孕妇或产后患者慎用无创通气。发展细菌性肺炎和MODS的迹象预示着NIV失败的机会。合并发病率并不是NIV失败的有力预测指标。避免插管可以减少并发症,特别是免疫功能低下的患者。使用类固醇对呼吸功能改善无显著影响。关键词:甲型H1N1流感感染,重症肺炎,NIV晚期失效
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引用次数: 0
Double hypoglossal canal: Study on crania of South Indian population and its clinical significance - 双舌下管:南印度人群颅骨的研究及其临床意义
Pub Date : 2016-01-01 DOI: 10.24896/JRMDS.V4I2.195
Gajanand Rp, G. Vanitha, C. Teli, H. Kadlimatti
Background: Hypoglossal canal is a permanent component of skull of human and animal. Situated anterior to occipital condyles, transmits hypoglossal nerve and meningeal branch of ascending pharyngeal artery and emissary vein. Aim: To find the incidence of double hypoglossal canal in crania of South Indian population and its clinical importance. Materials and methods:84 macerated dry skulls of unknown age and sex were collected from Department of Anatomy, ESIC Medical College Gulbarga and from Sharavathi Dental College Shivamogga Karnataka, India. Each skull was observed for doubling of hypoglossal canal. Results: Out of 84 skulls, 29 skulls showed doubling of hypoglossal canal. Among them 10 showed bilateral duplication and 19 unilateral (10 on right and 9 on left side). Incidence calculated as 34.5%. Conclusion: Double hypoglossal canal is important clinically, it may trap the hypoglossal nerve during ossification of occipital bone and useful for surgeons and radiologists and anthropologists. Key words: Double hypoglossal canal, emissary vein, hypoglossal nerve, neoplasms, occipital bone
背景:舌下管是人类和动物颅骨的永久组成部分。位于枕髁前,传递舌下神经和咽升动脉及使团静脉的脑膜支。目的:了解南印度人群颅内双舌下管的发生率及其临床意义。材料和方法:84个年龄和性别不详的经浸湿的干颅骨分别来自印度古尔巴加ESIC医学院解剖系和印度卡纳塔克邦Shivamogga的Sharavathi牙科学院。观察每个颅骨有无舌下管重叠。结果:84例颅骨中29例出现舌下管加倍。其中双侧重复10例,单侧重复19例(右侧10例,左侧9例)。发病率计算为34.5%。结论:双舌下管在临床上具有重要的应用价值,在枕骨骨化过程中,双舌下管可能夹持舌下神经,对外科医生、放射科医生和人类学家有一定的参考价值。关键词:双舌下管,特使静脉,舌下神经,肿瘤,枕骨
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引用次数: 1
Evaluation of metacognitive awareness of reading strategies among medical students 医学生阅读策略元认知意识的评价
Pub Date : 2016-01-01 DOI: 10.24896/JRMDS.V4I3.205
Pallavi Panchu, Biju Bahuleyan, K. Seethalakshmi, Tom Thomas
Background- Medical students are expected to be skilled readers and continuous learners. For a lifelong learner, metacognitive awareness of reading strategy is a necessary skill to obtain good academic outcome. The present study was done to evaluate the metacognitive awareness of reading strategies of first year medical students. Aims: To analyze the overall metacognitive awareness of reading strategies and also the subscales like global reading strategies, problem solving and support reading strategies in first year medical students and the impact of gender on these. Methods: Metacognitive awareness of reading strategies inventory (MARSI), a validated tool was administered to all the willing participants of the study group. The data obtained was analyzed using chi square and paired t test. Results: The overall metacognitive awareness of reading strategies was found to be high in our students. Problem solving strategies was utilized most followed by support reading strategies and global reading strategies. On comparing the influence of the sexes, it was noticed that females use better overall reading strategies which was significant. On comparing subscales, both the genders prefer using problem solving skills while the other subscales are used more by females. Conclusion: From our study we conclude that our learners have good metacognitive awareness regarding reading skills but does the skill turn into practice to achieve good academic scores remains to be seen. We suggest that curriculum should be so designed to help the students use all the subscales and hence all the strategies to become effective learners. Key words: MARCI, Medical students, Global strategies, Problem solving strategies, Support reading strategies.
背景-医学生被期望成为熟练的读者和持续的学习者。对于终身学习者来说,阅读策略的元认知意识是获得良好学习成绩的必要技能。本研究旨在评估医学生对阅读策略的元认知意识。目的:分析医学生对阅读策略的整体元认知意识、整体阅读策略、问题解决策略和支持阅读策略的子量表以及性别对这些子量表的影响。方法:对研究对象进行阅读策略元认知意识量表(MARSI)测试。所得资料采用卡方检验和配对t检验进行分析。结果:我校学生对阅读策略的元认知意识总体较高。学生使用最多的是问题解决策略,其次是辅助阅读策略和全局阅读策略。在比较性别的影响时,我们注意到女性使用更好的整体阅读策略,这是显著的。在比较子量表上,男女都更倾向于使用解决问题的能力,而其他子量表则被女性更多地使用。结论:从我们的研究中我们得出结论,我们的学习者在阅读技能方面具有良好的元认知意识,但这种技能是否转化为实践以取得良好的学习成绩还有待观察。我们建议课程的设计应该帮助学生使用所有的子量表,从而成为有效的学习者。关键词:MARCI,医学生,全局策略,问题解决策略,支持阅读策略
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引用次数: 4
Correlation and comparison of CT Urography and non contrast MR Urography in evaluation of malignant urinary tract lesions- A study of 54 patients CT尿路造影与非对比MR尿路造影评价恶性尿路病变的相关性及比较——附54例患者的研究
Pub Date : 2016-01-01 DOI: 10.24896/JRMDS.V4I3.209
Makada Mt, Thummar Kk
Background: Now a day with wider availability of multislice CT scanner and modern MR machines, it is possible to characterize various malignant urinary tract lesions with greater details on imaging. Aims and objective : To characterize various malignant urinary tract lesions on the basis of their location, internal characteristics, adjacent and distant spread and histopathological correlation on imaging by CT Urography and non contrast MR Urography and to compare the results by these two modalities. Material and Method: Selected patients underwent CT urography in 16 slice CT scan machine and non contrast MR urography in 1.5 T 16 channel MRI machine. Results: Kidney is most commonly involved organ by malignant lesions in urinary tract with renal cell carcinoma is frequently observed malignancy. CT Urography is better modality for internal characterization and adjacent vascular spread of malignant lesion than non-contrast MR Urography. Conclusion: For internal characterization and spread of malignant urinary tract lesions, CT Urography is better modality than non-contrast MR Urography. Key words: CT Urography, non contrast MR Urography, malignant lesions, urinary tract.
背景:随着多层螺旋CT扫描仪和现代磁共振成像仪的广泛应用,可以更详细地描述各种恶性尿路病变的影像学特征。目的与目的:通过CT尿路造影与非对比MR尿路造影对各种恶性尿路病变的定位、内部特征、邻近及远处扩散、组织病理相关性等特征进行鉴别,并比较两种方式的结果。材料与方法:选择患者在16层CT机上行CT尿路造影,在1.5 T 16通道MRI机上行非对比MR尿路造影。结果:肾是泌尿道恶性病变最常累及的器官,肾细胞癌是常见的恶性肿瘤。CT尿路造影对恶性病变的内部特征和邻近血管的扩散比磁共振尿路造影更好。结论:对于恶性尿路病变的内部特征及扩散,CT尿路造影优于MR尿路造影。关键词:CT尿路造影,非对比MR尿路造影,恶性病变,尿路。
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引用次数: 0
Modalities of treatment for segmental tibia fracture 胫骨节段性骨折的治疗方法
Pub Date : 2016-01-01 DOI: 10.24896/jrmds.v4i3.212
P. Patel, Ketan Kakani, Pratik Prajapati, Viral G. Prajapati, S. Patil
Background: Segmental tibia fractures (AO 42-C2) are defined by two or more distinct fracture lines isolating an interposed cortical segment which excludes butterfly fragmentation. Severe soft tissue defects are common due to their association with high energy trauma mechanisms of injury. Objectives: This study is an attempt to observe the various outcome of operative management of segmental tibia fracture treated by various modalities like intramedullary nailing, plating and external fixator. The results have been studied in depth to determine which modality is better for management of this type of fracture. Material & Methods: This is a prospective study of 25 cases of segmental tibia fracture treated by intra medullary nailing or plating or external fixator with minimum 6 months of follow up. All cases are evaluated according to time of union, complications, range of motion and modified knee society score. Modified knee society Score on residual effects on clinical ground at final examination. Points are given for pain, function and range of motion in modified knee society score. Result: Mean knee ROM in intramedullary nailing group is 118, while in plating group is 113.33.Average time of union in intramedullary nailing group is 18.61weeks; while in plating group is 25.33 weeks. Result according to Modified knee society score was found to be excellent to good in 18(72%) patients.11(73%) patients treated by interlocking intramedullary nailing had excellent to good knee score. Conclusion: Interlocking intramedullary nailing is a excellent method of treatment for the segmental tibia fracture as it provides rotational stability, gives excellent to good result, lower rate of complications and good knee ROM. Key words: Segmental tibia fracture, Modified knee society score, Intramedullary nailing.
背景:节段性胫骨骨折(AO 42-C2)被定义为两条或两条以上明显的骨折线,分离出中间的皮质节段,不包括蝶形骨折。严重的软组织缺损是常见的,因为它们与损伤的高能创伤机制有关。目的:观察髓内钉、钢板、外固定架等不同手术方式治疗胫骨节段性骨折的疗效。研究人员对结果进行了深入研究,以确定哪种方式更适合治疗这种类型的骨折。材料与方法:这是一项前瞻性研究,25例胫骨节段性骨折采用髓内钉或钢板或外固定架治疗,随访至少6个月。所有病例均根据愈合时间、并发症、活动范围和改良膝关节社会评分进行评估。改良膝关节社会评分在期末检查中对临床基础的残留影响。在改良膝关节社会评分中对疼痛、功能和活动范围进行评分。结果:髓内钉组膝关节平均ROM为118,钢板组膝关节平均ROM为113.33。髓内钉组平均愈合时间为18.61周;而对照组为25.33周。结果18例(72%)患者经改良膝关节社会评分为优至良,11例(73%)患者经交锁髓内钉治疗后膝关节评分为优至良。结论:交锁髓内钉治疗胫骨节段性骨折具有旋转稳定性好、疗效好、并发症发生率低、膝关节ROM良好等优点。关键词:胫骨节段性骨折,改良膝关节社会评分,髓内钉治疗。
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引用次数: 1
Anti-mutated citrullinatedvimentin antibody for predicting the activity of rheumatoid arthritis 抗突变瓜氨酸蛋白抗体预测类风湿关节炎的活动性
Pub Date : 2016-01-01 DOI: 10.24896/JRMDS.V4I4.226
Z. Soleimani, K. Esalatmanesh, M. Orangi
Background: Anti-citrullinated protein/peptide antibodies (ACPAs) are a heterogeneous family of autoantibodies, targeting citrullinated proteins. We investigated the relationship between serum levels of anti-mutated citrullinatedvimentin antibody (anti-MCV) and rheumatoid arthritis (RA) activity. Method: A total of 271 consecutive female patients with diagnosis of RA who met the ACR/EULAR criteria were enrolled. The disease activity was measured by the Disease Activity Score in 28 joints-erythrocyte sedimentation rate (DAS28-ESR). Anti-MCV was measured by enzyme-linked immunosorbent assay using a commercial kit with a cut-off value for positivity >20 U/mL. Results: Anti-MCV was positive in 153 (56.5%) patients. Disease in anti-MCV positive patients was significantly more active. A new composite index for predicting disease activity was constructed by replacing ESR with anti-MCV in the DAS28 model. There was a correlation between the absolute scores of DAS28-anti-MCV and DAS28-ESR scores. The new composite index best cut-off values corresponding to DAS28-ESR values of 2.6, 3.2, and 5.1 were 2.94, 3.17, and 4.87, respectively. The patients were re-categorized based on the new threshold values calculated by ROC curve analysis. There was agreement between the DAS28-anti-MCV categories and DAS28-ESR disease activity categories. Conclusions: Based on the correlation between anti-MCV levels with RA disease activity index, we conclude that anti-MCV may be a useful test to determine disease activity in RA. Keywords: rheumatoid arthritis, disease activity scores in 28 joints (DAS28), anti-mutated citrullinatedvimentin (anti-MCV)
背景:抗瓜氨酸蛋白/肽抗体(ACPAs)是一种针对瓜氨酸蛋白的异质自身抗体家族。我们研究了抗突变瓜氨酸蛋白抗体(anti-MCV)水平与类风湿关节炎(RA)活性的关系。方法:入选符合ACR/EULAR标准的连续271例RA女性患者。疾病活动性通过28个关节疾病活动性评分-红细胞沉降率(DAS28-ESR)来测量。采用酶联免疫吸附法测定抗mcv,使用商业试剂盒,阳性临界值为>20 U/mL。结果:153例(56.5%)患者抗mcv阳性。抗mcv阳性患者的疾病明显更活跃。在DAS28模型中,用anti-MCV代替ESR,构建了一种新的预测疾病活动性的复合指标。DAS28-anti-MCV绝对评分与DAS28-ESR评分存在相关性。DAS28-ESR值为2.6、3.2和5.1所对应的新综合指数最佳临界值分别为2.94、3.17和4.87。根据ROC曲线分析计算的新阈值对患者进行重新分类。DAS28-anti-MCV分类和DAS28-ESR疾病活动分类之间存在一致。结论:基于抗mcv水平与RA疾病活动性指数的相关性,我们认为抗mcv可能是判断RA疾病活动性的有效指标。关键词:类风湿关节炎,28关节疾病活动度评分(DAS28),抗突变瓜氨酸蛋白(anti-MCV)
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引用次数: 1
Myxoid Liposarcoma- A case Report 粘液样脂肪肉瘤1例报告
Pub Date : 2016-01-01 DOI: 10.5455/JRMDS.20164221
S. Pawar, Shilpa Gupta, K. Ghorpade, A. Saraf
We present a case of 62 year old female with tumor mass excised from right calf muscle. Histopathology and immunohistochemistry findings are compatible with a diagnosis of Myxoid Liposarcoma. We present a brief review of Myxoid Liposarcoma.
我们报告一个62岁女性右小腿肌肉肿瘤肿块切除的病例。组织病理学和免疫组织化学结果与黏液样脂肪肉瘤的诊断一致。我们就黏液样脂肪肉瘤作一简要综述。
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引用次数: 0
Hepatitis B infection and vaccination: Knowledge, Attitude and Practices among primary health care personnel in Lucknow - 乙型肝炎感染和疫苗接种:勒克瑙初级卫生保健人员的知识、态度和做法
Pub Date : 2016-01-01 DOI: 10.5455/jrmds.20164110
Mukesh Shukla, S. Tyagi, Neeraj Gupta
Background: Hepatitis B is a major global health problem and one of the most serious type of viral hepatitis, but it can be prevented with strategies like safe and effective vaccination, increasing awareness and by adhering to universal precautions. Objective: The present study aimed to assess the knowledge attitude and practice concerning Hepatitis B infection among the health care personnel in selected Primary Health Care Centres in Lucknow. Materials and methods: Cross-Sectional study was conducted among health care personnel working at the Primary Health Centres in Lucknow. A total of 89 health care personnel comprising of medical officers, staff nurses, laboratory technicians, pharmacists including class IV workers present on the day of data collection were included in the study and interviewed using pretested questionnaire. Descriptive summary using frequencies, proportions and percentages were used to present study results. Result: Majority (93.4%) of the medical officers were aware about type of hepatitis, while knowledge regarding same was comparatively low among staff nurses, paramedical staff and class IV workers (20.0%, 21.8% and 4.5% respectively). Knowledge about symptoms of hepatitis B was found minimal (9.1%) among class IV workers and paramedical staff (18.7%) as compared to doctors (80.0%) and staff nurse (35.0%). Only 13.6% of class IV worker had concern to report each and every case of needle stick injury. Practice to strictly follow of universal precautions and biomedical waste management guidelines was found to be least (9.1% and 18.1% respectively) among class IV workers. Conclusion: The study revealed sub-optimal KAP in concern to several aspects of Hepatitis B infection among primary healthcare personnel. Therefore insights a need to increase the knowledge level as well ideal behaviour in practice through quality training and proper orientation programmes for health care personnel to prevent the spread of hepatitis B infection.
背景:乙型肝炎是一个主要的全球卫生问题,也是最严重的病毒性肝炎类型之一,但可以通过安全有效的疫苗接种、提高认识和坚持普遍预防措施等策略加以预防。目的:本研究旨在评估勒克瑙市选定的初级卫生保健中心卫生保健人员对乙型肝炎感染的知识、态度和行为。材料和方法:在勒克瑙初级保健中心工作的卫生保健人员中进行了横断面研究。研究共纳入89名医务人员,包括收集数据当日在场的医务人员、护士长、实验室技术人员、药剂师(包括IV级工作人员),并使用预测问卷进行访谈。描述性总结使用频率,比例和百分比来呈现研究结果。结果:绝大多数医务人员(93.4%)对肝炎类型有所了解,而普通护士、辅助医务人员和四级工作人员对肝炎类型的了解程度相对较低(分别为20.0%、21.8%和4.5%)。与医生(80.0%)和护士(35.0%)相比,IV类工作人员和辅助医务人员(18.7%)对乙型肝炎症状的了解最少(9.1%)。只有13.6%的IV类工人关心报告每一起针刺伤病例。在第四类工人中,严格遵守普遍预防措施和生物医学废物管理准则的做法最少(分别为9.1%和18.1%)。结论:该研究揭示了初级卫生保健人员乙型肝炎感染的几个方面的次优KAP。因此,需要通过对卫生保健人员的高质量培训和适当的定向规划来提高知识水平和实践中的理想行为,以防止乙型肝炎感染的传播。
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引用次数: 2
A study on visual outcome after laser photocoagulation in diabetic retinopathy cases 激光光凝治疗糖尿病视网膜病变的疗效观察
Pub Date : 2016-01-01 DOI: 10.24896/JRMDS.V4I1.177
Hetaj K. Sheth, Kshama B Popat, Neeti R. Sheth, Vimal J. Vyas
Background: Diabetic retinopathy (DR) is one of the common causes of blindness in the world. Chronic hyperglycemia in diabetes causes progressive dysfunction of the retinal vasculature (microangiopathy) causing retinal hypoxia leading to expression of „Vascular endothelial growth factor‟ (VEGF) and „neovascularization‟. Laser photocoagulation is used to convert hypoxic areas into anoxic areas thus decreasing chances of release of VEGF and hence neovascularization. Aim: To study the visual outcome after laser retinal photocoagulation in DR cases. Material and Methods: The study was carried out on 80 eyes of 44 patients presenting at Department of Ophthalmology, P. D. U. Govt. Medical College, Rajkot who had DR and underwent laser retinal photocoagulation during period of November 2012 to September 2014. All patients underwent assessment for visual acuity, anterior segment examination, posterior segment examination with +90 Dioptre lens and fundus fluorescein angiography. (FFA). Then laser retinal photocoagulation was done. After laser treatment, patients were assessed for best corrected visual acuity (BCVA) on 1week, 1 month, 3 months and 6 months and the results were analysed. Results: 80% of the patients showed improvement in BCVA, 17.5% of the patient maintained same BCVA and 2.5% patients showed deterioration in BCVA which was statistically significant (paired t-test, p<0.0001). Conclusion: Diabetic retinopathy causes significant dysfunction of retinal vasculature and hence retina, hampering vision. Timely treatment with laser retinal photocoagulation prevents further dysfunction and salvages involved retina causing statistically significant improvement in vision and quality of life. Keywords: Diabetic Retinopathy, Visual Acuity, Laser retinal photocoagulation.
背景:糖尿病视网膜病变(DR)是世界上常见的致盲原因之一。糖尿病慢性高血糖导致视网膜血管进行性功能障碍(微血管病变),导致视网膜缺氧,导致“血管内皮生长因子”(VEGF)表达和“新生血管”形成。激光光凝用于将缺氧区域转化为缺氧区域,从而减少VEGF释放的机会,从而减少新生血管的形成。目的:探讨激光视网膜光凝治疗DR后的视力效果。材料和方法:本研究对2012年11月至2014年9月期间在拉杰科特p.d.政府医学院眼科就诊的44例DR患者的80只眼睛进行了激光视网膜光凝。所有患者均接受了视力评估、+90屈光度晶状体前段检查、后段检查和眼底荧光素血管造影。(FFA)。然后进行激光视网膜光凝。分别于激光治疗后第1周、第1个月、第3个月和第6个月对患者进行最佳矫正视力(BCVA)评估,并对结果进行分析。结果:80%的患者BCVA改善,17.5%的患者BCVA维持不变,2.5%的患者BCVA恶化,差异有统计学意义(配对t检验,p<0.0001)。结论:糖尿病视网膜病变导致视网膜血管功能明显紊乱,影响视力。及时使用激光视网膜光凝治疗可以防止进一步的功能障碍,并挽救涉及视网膜,导致视觉和生活质量的统计学显著改善。关键词:糖尿病视网膜病变,视力,激光视网膜光凝
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引用次数: 0
Aggressiveness and increased lymph node involvement in younger patients (<40 years) suffering from breast cancer 年轻乳腺癌患者(<40岁)的侵袭性和淋巴结累及增加
Pub Date : 2016-01-01 DOI: 10.24896/jrmds.v4i1.175
N. Gupta, Asha Satwara, G. Bala, Jignasha Mungra, P. Santwani
Introduction: Breast cancer is 4th leading cause of death in many parts of world. Unexplained increase in aggressiveness and more number of lymph node involvements in young females with breast cancer is of interest. Objective: This study is designed to assess the lymph node involvement in younger patients (<40 years) suffering from breast cancer Method: This study has been done on MRM specimen of 90 females of breast cancer from (Jan 2014-jan 2015) in pathology department of Shri. M. P. Shah. Govt. Medical College, Jamnagar. This study includes the age, lymph node status, grading and staging. Results: After analyzing, only 2(2.22%) females 40 years has been diagnosed as invasive breast cancer. 63% females 3 lymph node positive while only 34% females >40 years showing >3 lymph node positivity. Out of this statistics younger patients showing most of lymph nodes out of total to be positive as compared to older age group as it affects TNM staging and treatment protocol. Conclusion: Increase in risk of lymph node involvement in younger patients (25-40). All the young women in their 20s and 30s should examine herself and every 3 years by her health care professionals.
导言:在世界许多地方,乳腺癌是第四大死因。年轻女性乳腺癌的侵袭性不明原因的增加和更多的淋巴结受累是令人感兴趣的。目的:本研究旨在评估>3淋巴结阳性的年轻患者(40岁)的淋巴结受累情况。在这一统计数据中,年轻患者显示,与年龄较大的患者相比,大部分淋巴结呈阳性,因为这影响了TNM的分期和治疗方案。结论:年轻患者(25-40岁)淋巴结受累的风险增加。所有20多岁和30多岁的年轻女性都应该每三年让她的保健专业人员检查一次自己。
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引用次数: 0
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Journal of Research in Medical and Dental Science
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