Journal of Small Animal Practice最新文献

Objective: To describe the surgical technique, associated complications and 12-month outcomes in dogs that underwent laparoscopic treatment of prostatic cysts.

Materials and methods: The medical records of dogs with prostatic cysts that were managed laparoscopically between 2017 and 2022 at two referral institutions were retrospectively reviewed. Intra- and post-operative complications were evaluated, and patients were required to have a minimum follow-up of 12 months for inclusion in the study.

Results: Twelve client-owned dogs met the inclusion criteria. A three- or four-port technique was used depending on the surgeon's preference. Following deroofing of the prostatic cyst, urethral integrity was assessed intraoperatively. The cystic cavity was inspected for leakage while injecting saline into the distal urethra, confirming the absence of communication between the urethra and the prostatic cyst. The omentum was anchored to the prostatic body using either simple interrupted sutures or haemostatic clips, with the latter method considered subjectively more challenging by the authors. No major intra- or post-operative complications were reported. Minor intraoperative complications occurred in three of 12 patients, consisting of self-limiting haemorrhage. Minor post-operative complications included one case of transient urinary tenesmus, which resolved within 24 hours, and mild haematuria in one dog, which lasted for 3 days. No recurrence of the prostatic cysts was observed over the 12-month follow-up period.

Clinical significance: Laparoscopic excision with omentalisation is a feasible, effective and safe therapeutic approach for prostatic cysts in dogs confirmed to lack a communication between the prostatic cyst and the urethra.

A 10-year-old male mixed-breed dog presented with vomiting and anuria. The dog was living indoors, and no trauma was reported by the owner. Ultrasonography and a retrograde urethrogram revealed the presence of a urinary bladder leakage. A celiotomy was performed to repair a urinary bladder tear, along with a biopsy of the urinary bladder wall. Histopathological features consisted of lymphoplasmacytic cystitis with haemorrhages and multifocal fibrotic areas within the muscular layers. Spontaneous rupture of the urinary bladder without evidence of trauma is a well-known, though rare, condition in human medicine. The chronic inflammation detected in the present case, along with fibrosis, caused the weakening of the urinary bladder wall, leading to perforation. This is the first documented veterinary case of spontaneous rupture of the urinary bladder secondary to chronic inflammation and highlights the importance of including this condition in the differential diagnosis of patients presenting with uroperitoneum without underlying trauma.

Objectives: We aimed to determine if oral faecal microbiota transplantation improves indices of glycaemic control, changes the faecal dysbiosis indices, alters faecal short-chain fatty acid and bile acid profiles and increases serum glucagon-like-peptide 1 concentrations in diabetic dogs.

Materials and methods: In this prospective randomised, placebo-controlled, double-blinded pilot study, we recruited nine diabetic dogs (five faecal microbiota transplantation and four placebo) and nine healthy controls.

Results: Compared to healthy dogs, diabetic dogs had altered faecal short-chain fatty acid and bile acid profiles. In the first 30 days, the faecal microbiota transplantation group had a more rapid decline in interstitial glucose; however, the mean interstitial glucose of the faecal microbiota transplantation recipients did not differ from the placebo recipients at the end of the study. Compared with placebo, faecal microbiota transplantation recipients had a decreased 24-hour water intake at day 60 and increased faecal abundance of Faecalibacterium.

Clinical significance: This study provides a proof of concept for faecal microbiota transplantation in canine diabetes, and its data could inform the design of future large-scale studies. Further investigation is required to determine whether faecal microbiota transplantation would have any role as an adjunctive therapy in canine diabetes and to elucidate the mechanisms by which faecal microbiota transplantation may provide a beneficial clinical effect in canine diabetes.

Objectives: To describe accessory lung lobectomy, via right or left intercostal thoracotomy, intraoperative and postoperative complications and outcome in a small population of dogs.

Materials and methods: The medical records of 11 dogs that underwent accessory lung lobectomy at three veterinary institutions between 2009 and 2023 were reviewed. Signalment, history, physical examination, diagnostics, duration of hospitalisation, surgical approach, type of lobectomy, concurrent procedures, intraoperative and postoperative complications, duration of indwelling thoracic drain and short-term outcomes were recorded.

Results: Dogs underwent accessory lung lobectomy either via right (n = 9) or left (n = 2) intercostal thoracotomy. Partial (n = 6) or total lobectomy (n = 5) with stapler devices (n = 10) or surgical ligation (n = 1) was performed. Histopathology was performed in ten of 11 dogs and was consistent with pneumonia due to an infectious process or a migrating vegetable foreign body (n = 5), pulmonary carcinoma (n = 2), severe chronic neutrophilic and macrophagic pleuropneumonia (n = 1), pulmonary bullae (n = 1) or blastomycosis infection (n = 1). Iatrogenic trauma to the left caudal lung lobe occurred in one dog via left intercostal thoracotomy. The mean duration of indwelling thoracic drain was 2.7 days (range 1 to 4). Complications occurred postoperatively in six dogs. In five of six cases, short-term postoperative complications were classified as minor and included wound infection (n = 1), cough (n = 1), dyspnoea (n = 1), adverse reaction to medication (n = 1) and inappetence (n = 1). One case developed a major complication, pneumothorax with dehiscence of the lobectomy site, and revision surgery was required. All dogs survived hospital discharge.

Clinical significance: Accessory lung lobectomy is uncommon and can be performed either via left- or via right-sided intercostal thoracotomy.

Objective: To report the occurrence of transient atrial fibrillation in dogs with degenerative mitral valve disease (DMVD) American College of Veterinary Medicine (ACVIM) stage C/D, presenting with acute clinical signs.

Materials and methods: Retrospective multicentric case series of dogs with DMVD ACVIM stage C/D and transient atrial fibrillation (AF) hospitalised in referral centres (2020 to 2024). Signalment, clinical findings, treatments, electrocardiographic and echocardiographic data and outcomes were recorded.

Results: Eight dogs were included. All dogs presented for acute deterioration of clinical signs:tachypnoea with worsening cough (5/8) and syncopal episodes (3/8). Electrocardiographic findings were compatible with AF with a fast ventricular rate in all dogs. Active congestive heart failure (CHF) was identified in 5/8 patients. Antiarrhythmic treatment with digoxin (4/8), diltiazem (1/8) or digoxin/diltiazem (2/8) was instituted in seven dogs. Treatment for active CHF was also performed. Sinus rhythm was subsequently observed either during hospitalisation (4/8, average 30 hours) or at the first recheck after stabilisation (4/8, average 22 days). In 6/7 dogs, antiarrhythmic treatment was discontinued. Three dogs showed a recurrence of AF a few months after the first episode. Five dogs died of cardiac disease, two of which died suddenly.

Clinical significance: Paroxysmal AF has been previously described in dogs; the pathophysiological mechanism is presumed to be neurally mediated. Transient AF has not been extensively reported in dogs with clinically significant DMVD and is a possible event in dogs presenting with acute clinical signs and AF. The pathophysiological mechanism in this population may be slightly different from previously reported cases. After cardioversion, variation in clinical outcomes was observed.

Objectives: This article aims to analyse the safety of canine blood donation by describing the frequency and causes of any adverse reactions in donors.

Materials and methods: In this prospective study, any blood donor adverse reactions detected by the clinical staff during and immediately after donation were recorded. The owners of the dogs were also surveyed by a veterinary practitioner or veterinary nurse 3 days after donation, using a predefined questionnaire to assess for any clinical or behavioural changes. Data were collected between December 2020 and December 2021 from blood donors enrolled in an animal blood bank programme.

Results: From the 4439 blood donations, 37 (0.83%) adverse post-donation reactions were reported, with no other reactions identified in the remaining 4402 donations (99.17%). Of the total of donations in the studied period, 0.63% (n = 28) of canine donors developed a haematoma in the puncture area, 0.11% (n = 5) developed mild bleeding at the puncture site during the monitoring period, 0.045% (n = 2) developed a skin rash after clipping for donation, and 0.045% (n = 2) developed acute weakness, pallor, tachycardia and tachypnoea during the 30 minutes monitoring period, consistent with hypotension. In both cases showing acute signs of weakness, pallor, tachycardia and tachypnoea, all parameters stabilised and resolved within 10 to 15 minutes upon administration of a 10 mL/kg bolus over 10 minutes of intravenous NaCl. No other delayed reactions were reported by the owners other than the acute reactions already registered by the donation staff.

Clinical significance: The low incidence of post-donation reactions in this study is encouraging, suggesting that a high level of safety can be achieved in a structured canine blood donation programme.

Objective: This retrospective study aimed to evaluate the intraoperative isoflurane-sparing and cardiovascular effects of a combined infusion of remifentanil-lidocaine-ketamine versus remifentanil-ketamine for balanced anaesthesia in cats to investigate the effect of lidocaine infusion in various clinical situations.

Materials and methods: Among patients with various health statuses undergoing surgical procedures, 18 cats administered remifentanil-lidocaine-ketamine were compared with 20 cats administered remifentanil-ketamine. In the remifentanil-lidocaine-ketamine group, lidocaine was initially infused at 50 μg/kg/minute with a loading dose of 0.6 mg/kg, and the infusion rate was controlled depending on cardiovascular alterations. Linear regression was used to relate end-tidal isoflurane and cardiovascular effects, including blood pressure [expressed as the ratio of mild hypotension duration (mean arterial pressure <60 mmHg) to total anaesthesia time] and heart rate (interquartile range) with patient, surgical and anaesthetic variables including lidocaine infusion.

Results: In the remifentanil-lidocaine-ketamine group, the average lidocaine infusion rate during the entire anaesthetic period was 46.00 ± 12.00 (range: 22.67 to 64.63) μg/kg/minute. The multivariable regression model of end-tidal isoflurane showed a correlation with the duration of the procedure and lidocaine infusion. The end-tidal isoflurane concentration exhibited a significant reduction in the remifentanil-lidocaine-ketamine group (1.16% ± 0.19%), compared with that of the remifentanil-ketamine group (1.27% ± 0.14%). The association between lidocaine administration and hypotension was not significant, nor was that with heart rate.

Clinical significance: Although the use of intravenous lidocaine in cats has been associated with concerns regarding cardiovascular toxicity, the findings of this study suggest that lidocaine infusion, as part of the remifentanil-lidocaine-ketamine combination, can be considered a component of balanced anaesthesia in cats.