Pub Date : 2024-10-08DOI: 10.1016/j.jaac.2024.07.929
Lauren M O'Reilly,Chip Cotman,Trey V Dellucci,Casey A Pederson,Matthew C Aalsma,Hubert Izienicki
{"title":"Data Collection Among Sexual and Gender Minority Youth Involved in the Legal System.","authors":"Lauren M O'Reilly,Chip Cotman,Trey V Dellucci,Casey A Pederson,Matthew C Aalsma,Hubert Izienicki","doi":"10.1016/j.jaac.2024.07.929","DOIUrl":"https://doi.org/10.1016/j.jaac.2024.07.929","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"6 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142431101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-08DOI: 10.1016/j.jaac.2024.10.004
Jeffrey R Strawn,Tara S Peris
{"title":"Paternal Anxiety and Children's Anxiety and Related Symptoms: An Overlooked Risk Factor.","authors":"Jeffrey R Strawn,Tara S Peris","doi":"10.1016/j.jaac.2024.10.004","DOIUrl":"https://doi.org/10.1016/j.jaac.2024.10.004","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"9 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142431100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-07DOI: 10.1016/j.jaac.2024.09.008
Danella M Hafeman, Boris Birmaher
Randomized controlled trials (RCTs) of youth with mania are very challenging to conduct, given the low base rate of bipolar disorder (BD) and the relative rarity of mania (vs bipolar depression, which tends to be much more common). Thus, many of the RCTs are relatively small, and it may be difficult to clinically interpret results. At the same time, findings about which anti-manic medications are most effective in youth are of critical importance, both because (1) poorly treated mania can lead to substantial negative psychosocial consequences, and (2) these medications can have significant adverse effects. In this setting, network meta-analyses (NMAs) are key to summarize extremely valuable work in a way that is meaningful and relevant to clinicians.
{"title":"Editorial: A Meta-Analysis of the Treatment of Acute Mania in Youth: Why Do Atypical Antipsychotics Work Better Than Mood Stabilizers?","authors":"Danella M Hafeman, Boris Birmaher","doi":"10.1016/j.jaac.2024.09.008","DOIUrl":"10.1016/j.jaac.2024.09.008","url":null,"abstract":"<p><p>Randomized controlled trials (RCTs) of youth with mania are very challenging to conduct, given the low base rate of bipolar disorder (BD) and the relative rarity of mania (vs bipolar depression, which tends to be much more common). Thus, many of the RCTs are relatively small, and it may be difficult to clinically interpret results. At the same time, findings about which anti-manic medications are most effective in youth are of critical importance, both because (1) poorly treated mania can lead to substantial negative psychosocial consequences, and (2) these medications can have significant adverse effects. In this setting, network meta-analyses (NMAs) are key to summarize extremely valuable work in a way that is meaningful and relevant to clinicians.</p>","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-03DOI: 10.1016/j.jaac.2024.07.928
Sahana Kribakaran, Stephanie N DeCross, Paola Odriozola, Katie A McLaughlin, Dylan G Gee
<p><strong>Objective: </strong>Nearly 65% of youth experience trauma, and up to one-third of youth with trauma exposure face profound mental health sequelae. There remains a need to elucidate factors that contribute to psychopathology following trauma exposure, and to optimize interventions for youth who do not benefit sufficiently from existing treatments. Here, we probe safety signal learning (SSL), which is a mechanism of fear reduction that leverages learned safety to inhibit fear in the presence of threat-associated stimuli and has been shown to attenuate fear via a hippocampal-cingulate--specifically, a dorsal anterior cingulate cortex (dACC)--pathway.</p><p><strong>Method: </strong>The present study used behavioral and task-based functional magnetic resonance imaging data to examine age-related associations between interpersonal trauma exposure and the behavioral and neural correlates (ie, activation and functional connectivity) of SSL in a group of 102 youth (aged 9-19 years; 46 female, 56 male) with (n = 52) and without (n = 50) interpersonal trauma exposure. Primary analyses examined anterior hippocampal activation and anterior hippocampus-dACC functional connectivity. Exploratory analyses examined centromedial (CMA) and laterobasal (LBA) amygdala activation and anterior hippocampal, CMA, and LBA functional connectivity with additional anterior cingulate subregions (ie, subgenual anterior cingulate cortex [sgACC] and rostral anterior cingulate cortex [rosACC]).</p><p><strong>Results: </strong>Both youth with and without interpersonal trauma exposure successfully learned conditioned safety, which was determined by using self-report of contingency awareness. Youth with interpersonal trauma exposure (relative to youth in the comparison group) exhibited age-specific patterns of lower hippocampal activation (F<sub>2,96</sub> = 3.75, p<sub>FDR</sub> = .049, η<sub>p</sub><sup>2</sup> = 0.072), and, in exploratory analyses, showed heightened centromedial amygdala activation (F<sub>1,96</sub> = 5.37, p<sub>FDR</sub> = .046, η<sub>p</sub><sup>2</sup> = 0.053) and an age-related decrease in hippocampal-sgACC functional connectivity during SSL (F<sub>1,94</sub> = 10.68, p<sub>FDR</sub> = .015, η<sub>p</sub><sup>2</sup> = 0.102). We also show that hippocampal-sgACC functional connectivity mediated the association between interpersonal trauma exposure and post-traumatic stress disorder symptoms in an age-specific manner in the overall sample.</p><p><strong>Conclusion: </strong>Together, these findings suggest that although age- and trauma-specific differences in the neural correlates of SSL may relate to the development of psychopathology, youth with interpersonal trauma exposure demonstrate successful learning of conditioned safety over time.</p><p><strong>Diversity & inclusion statement: </strong>We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure sex and gender balance in the recruitment of huma
{"title":"Developmental Differences in a Hippocampal-Cingulate Pathway Involved in Learned Safety Following Interpersonal Trauma Exposure.","authors":"Sahana Kribakaran, Stephanie N DeCross, Paola Odriozola, Katie A McLaughlin, Dylan G Gee","doi":"10.1016/j.jaac.2024.07.928","DOIUrl":"10.1016/j.jaac.2024.07.928","url":null,"abstract":"<p><strong>Objective: </strong>Nearly 65% of youth experience trauma, and up to one-third of youth with trauma exposure face profound mental health sequelae. There remains a need to elucidate factors that contribute to psychopathology following trauma exposure, and to optimize interventions for youth who do not benefit sufficiently from existing treatments. Here, we probe safety signal learning (SSL), which is a mechanism of fear reduction that leverages learned safety to inhibit fear in the presence of threat-associated stimuli and has been shown to attenuate fear via a hippocampal-cingulate--specifically, a dorsal anterior cingulate cortex (dACC)--pathway.</p><p><strong>Method: </strong>The present study used behavioral and task-based functional magnetic resonance imaging data to examine age-related associations between interpersonal trauma exposure and the behavioral and neural correlates (ie, activation and functional connectivity) of SSL in a group of 102 youth (aged 9-19 years; 46 female, 56 male) with (n = 52) and without (n = 50) interpersonal trauma exposure. Primary analyses examined anterior hippocampal activation and anterior hippocampus-dACC functional connectivity. Exploratory analyses examined centromedial (CMA) and laterobasal (LBA) amygdala activation and anterior hippocampal, CMA, and LBA functional connectivity with additional anterior cingulate subregions (ie, subgenual anterior cingulate cortex [sgACC] and rostral anterior cingulate cortex [rosACC]).</p><p><strong>Results: </strong>Both youth with and without interpersonal trauma exposure successfully learned conditioned safety, which was determined by using self-report of contingency awareness. Youth with interpersonal trauma exposure (relative to youth in the comparison group) exhibited age-specific patterns of lower hippocampal activation (F<sub>2,96</sub> = 3.75, p<sub>FDR</sub> = .049, η<sub>p</sub><sup>2</sup> = 0.072), and, in exploratory analyses, showed heightened centromedial amygdala activation (F<sub>1,96</sub> = 5.37, p<sub>FDR</sub> = .046, η<sub>p</sub><sup>2</sup> = 0.053) and an age-related decrease in hippocampal-sgACC functional connectivity during SSL (F<sub>1,94</sub> = 10.68, p<sub>FDR</sub> = .015, η<sub>p</sub><sup>2</sup> = 0.102). We also show that hippocampal-sgACC functional connectivity mediated the association between interpersonal trauma exposure and post-traumatic stress disorder symptoms in an age-specific manner in the overall sample.</p><p><strong>Conclusion: </strong>Together, these findings suggest that although age- and trauma-specific differences in the neural correlates of SSL may relate to the development of psychopathology, youth with interpersonal trauma exposure demonstrate successful learning of conditioned safety over time.</p><p><strong>Diversity & inclusion statement: </strong>We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure sex and gender balance in the recruitment of huma","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.jaac.2024.07.141
Jeremy D. Wortzel MD, MPH, MPhil, Ianna Hondros-McCarthy DO, Joshua D. Feder MD
{"title":"UNDERSTANDING THE IMPORTANCE OF GREEN SPACE TO IMPROVE YOUTH MENTAL HEALTH FROM THE CLINIC TO THE COMMUNITY","authors":"Jeremy D. Wortzel MD, MPH, MPhil, Ianna Hondros-McCarthy DO, Joshua D. Feder MD","doi":"10.1016/j.jaac.2024.07.141","DOIUrl":"10.1016/j.jaac.2024.07.141","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"63 10","pages":"Pages S27-S28"},"PeriodicalIF":9.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.jaac.2024.07.113
Carol M. Larroque MD, Maria E. McGee MD, MS, MPH
{"title":"THE EFFECTS OF CLIMATE CHANGE ON FAMILIES GLOBALLY","authors":"Carol M. Larroque MD, Maria E. McGee MD, MS, MPH","doi":"10.1016/j.jaac.2024.07.113","DOIUrl":"10.1016/j.jaac.2024.07.113","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"63 10","pages":"Page S20"},"PeriodicalIF":9.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.jaac.2024.07.071
Jiwon Helen Wyman MD, MATS
{"title":"6.3 Balancing Power Differentials in Child Custody Disputes Through Evidence-Based Interviewing of Children and Youth","authors":"Jiwon Helen Wyman MD, MATS","doi":"10.1016/j.jaac.2024.07.071","DOIUrl":"10.1016/j.jaac.2024.07.071","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"63 10","pages":"Page S9"},"PeriodicalIF":9.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142428465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.jaac.2024.07.051
Alison M. Duncan MD, Laurie Thomas MD
{"title":"2.3 Catatonia and Altered Mental Status in the Pediatric Population","authors":"Alison M. Duncan MD, Laurie Thomas MD","doi":"10.1016/j.jaac.2024.07.051","DOIUrl":"10.1016/j.jaac.2024.07.051","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"63 10","pages":"Page S4"},"PeriodicalIF":9.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.jaac.2024.07.075
Wendy J. Spettigue MD
{"title":"7.1 The Medical, Psychological, and Cognitive Effects of Insufficient Nutrition on the Developing Brain","authors":"Wendy J. Spettigue MD","doi":"10.1016/j.jaac.2024.07.075","DOIUrl":"10.1016/j.jaac.2024.07.075","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"63 10","pages":"Page S10"},"PeriodicalIF":9.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.jaac.2024.07.076
Jennifer L. Couturier MD
{"title":"7.2 Starvation as a Consequence of Atypical Anorexia Nervosa","authors":"Jennifer L. Couturier MD","doi":"10.1016/j.jaac.2024.07.076","DOIUrl":"10.1016/j.jaac.2024.07.076","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"63 10","pages":"Page S10"},"PeriodicalIF":9.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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