Journal of veterinary emergency and critical care最新文献_第7页

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-04-01 DOI: 10.1111/vec.13304

引用次数: 0

A proof-of-concept study evaluating cardiac compression techniques for cardiopulmonary resuscitation in laying hens (Gallus gallus) 评估用于蛋鸡心肺复苏的心脏按压技术的概念验证研究。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-03-25 DOI: 10.1111/vec.13369

Jessica Eisenbarth DVM, DACVECC, Charles O. Cummings DVM, Elizabeth A. Rozanski DVM, DACVIM, DACVECC, Emily Karlin DVM, DACVIM, John Rush DVM, DACVIM, DACVECC

Objective

To determine in adult chickens which of 3 CPR techniques, sternal compressions (SC), SC with interposed caudal coelomic compressions (ICCC), or lateral compressions (LC), results in the highest mean systolic (SAP), diastolic (DAP), and mean arterial pressure (MAP) as measured directly from the carotid artery.

Design

Prospective, nonblinded, experimental crossover study.

Setting

University teaching hospital laboratory.

Animals

Ten retired laying hens.

Interventions

Birds were sedated, anesthetized, and placed in dorsal recumbency. A carotid artery catheter was placed to directly measure arterial pressure. Ventricular fibrillation was induced with direct cardiac stimulation using a 9-Volt battery. Each bird then received 2 minutes of the 3 different cardiac compression techniques in a random order by 3 different compressors, with the compressor order also randomized. Birds were subsequently administered IV epinephrine, and transthoracic defibrillation was attempted. At the end of experimentation, each bird was euthanized, and simple gross necropsies were performed. Linear mixed models followed by pairwise paired t-tests were performed to evaluate differences in pressures generated by each technique.

Measurements and Main Results

The primary study outcomes were SAP, DAP, and MAP over 2 minutes of compressions for each compression technique. Pressures from ICCC (SAP: 27.6 ± 5.3 mm Hg, DAP: 18.7 ± 5.2 mm Hg, MAP: 21.7 ± 5.2 mm Hg) were significantly higher than those from LC (SAP: 18.9 ± 5.4 mm Hg, DAP: 11.6 ± 4.1 mm Hg, MAP: 14.1 ± 4.5 mm Hg). Pressures from SC (SAP: 24.5 ± 6.4 mm Hg, DAP: 15.2 ± 4.3 mm Hg, MAP: 18.3 ± 5.0 mm Hg) were not significantly different from ICCC or LC.

Conclusions

External compressions can generate detectable increases in arterial pressure in chickens with ventricular fibrillation. SC with ICCC generated significantly higher arterial pressures than LC. SC alone generated blood pressures that were not significantly different from those generated by SC with ICCC or LC.

目的确定在成年鸡的 3 种心肺复苏技术中，胸骨按压 (SC)、胸骨按压加尾椎腔按压 (ICCC) 或侧向按压 (LC) 可使直接从颈动脉测量的平均收缩压 (SAP)、舒张压 (DAP) 和平均动脉压 (MAP) 达到最高值：设计：前瞻性、非盲法、实验性交叉研究：动物：10 只退役蛋鸡十只退役蛋鸡：干预措施：对鸡进行镇静、麻醉和背卧位。放置颈动脉导管以直接测量动脉压。使用 9 伏电池直接刺激心脏诱发室颤。然后，每只鸟按随机顺序接受 3 种不同的心脏按压技术治疗 2 分钟，3 种不同的按压器的顺序也是随机的。随后对鸟类进行肾上腺素静脉注射，并尝试经胸除颤。实验结束后，对每只鸟实施安乐死，并进行简单的大体尸体解剖。通过线性混合模型和配对 t 检验来评估每种技术产生的压力差异：主要研究结果为每种按压技术按压 2 分钟后的 SAP、DAP 和 MAP。ICCC 的压力（SAP：27.6 ± 5.3 mm Hg；DAP：18.7 ± 5.2 mm Hg；MAP：21.7 ± 5.2 mm Hg）明显高于 LC 的压力（SAP：18.9 ± 5.4 mm Hg；DAP：11.6 ± 4.1 mm Hg；MAP：14.1 ± 4.5 mm Hg）。SC的压力（SAP：24.5 ± 6.4 mm Hg；DAP：15.2 ± 4.3 mm Hg；MAP：18.3 ± 5.0 mm Hg）与ICCC或LC无显著差异：结论：体外按压可使心室颤动患儿的动脉压明显升高。SC与 ICCC 产生的动脉压明显高于 LC。单独体外按压产生的血压与体外按压加 ICCC 或 LC 产生的血压没有显著差异。

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引用次数: 0

Use of FreeStyle Libre for continuous glucose monitoring in adult horses 使用 FreeStyle Libre 对成年马进行连续葡萄糖监测。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-03-08 DOI: 10.1111/vec.13367

Rafael Françoso DVM, MsC, PhD, Raquel Y. Baccarin DVM, MsC, PhD, Renata F. de Siqueira DVM, MsC, PhD, Carla B. Belli DVM, MsC, PhD

<div> <section> <h3> Objectives</h3> <p>To evaluate the feasibility of using the FreeStyle Libre (a continuous glucose monitoring system [CGMS]) for instantaneous continuous monitoring of interstitial glucose in adult horses and examine the applicability and accuracy of this system in horses submitted to combined glucose–insulin test (CGIT).</p> </section> <section> <h3> Design</h3> <p>Laboratory measurements and continuous glucose monitoring system (CGMS) readings were analyzed using a 2 × 2 factorial statistical model with repeated measures over time. This analysis assessed the effects of the test (factor 1), group (factor 2), and their interactions (test × group, test × time, and group × time). Pearson's correlation analysis was applied to blood glucose values. Mean comparisons were conducted using the <i>t</i>-test, and agreement between techniques was assessed via the Bland–Altman method, with a 95% confidence interval.</p> </section> <section> <h3> Setting</h3> <p>Field study on private horse farms in association with a veterinary school.</p> </section> <section> <h3> Animals</h3> <p>Ten healthy stallions were assigned to one of two groups based on their body condition scores (BCS). Group 1 (G1, <i>n</i> = 5) consisted of nonobese horses with a BCS of 5 or 6, while Group 2 (G2, <i>n</i> = 5) consisted of obese horses with a BCS of 7 or higher.</p> </section> <section> <h3> Interventions</h3> <p>A CGMS sensor was attached to the dorsolateral aspect of the proximal one third of each horse's neck. Laboratory blood glucose measurements and CGMS interstitial glucose readings were compared at different time points for up to 7 days after sensor fixation. Obese horses were also submitted to CGIT on Day 4.</p> </section> <section> <h3> Measurements and Main Results</h3> <p>A comparative analysis of glucose measurements obtained in G1 and G2 horses using the CGMS and enzymatic methods revealed significant group × time interactions (<i>P</i> < 0.001) and time effects (<i>P</i> < 0.001). No interactions were detected between group (<i>P</i> = 0.45), test (<i>P</i> = 0.62), group and test (<i>P</i> = 0.28), or time and test (<i>P</i> = 0.92). In G1 and G2, tests were significantly correlated (<i>r</i> = 0.84 and <i>P</i> = 0.00) at all time points (T0–T5). Agreement between the glucose values obtained using different methods was excellent despite a small time delay in CGMS detection of rapid changes in blood glucose.</p> </section> <section>

目的评估使用FreeStyle Libre（一种连续葡萄糖监测系统[CGMS]）瞬时连续监测成年马血糖的可行性，并检查该系统在接受葡萄糖-胰岛素联合试验（CGIT）的马匹中的适用性和准确性：设计：采用 2 × 2 因式统计模型对实验室测量结果和连续葡萄糖监测系统（CGMS）读数进行分析，并随时间进行重复测量。该分析评估了试验（因子 1）、组别（因子 2）及其交互作用（试验×组别、试验×时间和组别×时间）的影响。血糖值采用了皮尔逊相关分析法。平均值比较采用 t 检验，技术间的一致性采用 Bland-Altman 方法评估，置信区间为 95%：动物：十匹健康种公马被分配到不同的马场：根据身体状况评分（BCS），将 10 匹健康种公马分成两组。第一组（G1，n = 5）由 BCS 为 5 或 6 的非肥胖马组成，第二组（G2，n = 5）由 BCS 为 7 或更高的肥胖马组成：在每匹马颈部近三分之一处的背外侧安装 CGMS 传感器。在传感器固定后的 7 天内，比较不同时间点的实验室血糖测量值和 CGMS 间质葡萄糖读数。肥胖马也在第 4 天接受了 CGIT：使用 CGMS 和酶法对 G1 和 G2 马匹的葡萄糖测量值进行比较分析后发现，组别 × 时间之间存在显著的交互作用（P 结论）：结论：CGMS可用于间接评估接受CGIT的非肥胖和肥胖成年马的血糖状况（即基于间质葡萄糖测量值）。

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引用次数: 0

Performance evaluation of a Test&Treat rapid detection kit for the diagnosis of septic effusions in dogs and cats 用于诊断猫狗化脓性渗出物的 Test&Treat 快速检测试剂盒的性能评估。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-03-02 DOI: 10.1111/vec.13372

Noël K. Vezzi DVM, Selena L. Lane DVM, DACVECC, Britt A. Thevelein DVM, DACVECC, Benjamin M. Brainard VMD, DACVAA, DACVECC

Objective

To evaluate the sensitivity and specificity of a veterinary point-of-care (POC) luminometer-based kit for the diagnosis of septic peritoneal or pleural effusion in dogs and cats.

Design

Prospective study performed between January 2020 and July 2021.

Setting

University teaching hospital.

Animals

Forty-eight animals with naturally occurring peritoneal or pleural effusion collected by aseptic abdominocentesis or thoracocentesis.

Procedures

Effusion samples were split into filtered (using a 10-micron filter) and unfiltered aliquots and analyzed by the POC instrument according to the manufacturer's instructions and following variable incubation periods. Samples were also plated aerobically on standard and blood agar plates. Proprietary reagents were added to samples, causing bacterial ATP to generate bioluminescence that is detected by the luminometer. Bioluminescence values (relative light units [RLUs]) were recorded and compared with the presence of bacterial growth on the culture plates. Nucleated cell counts in native and filtered effusion samples were recorded.

Results

Twenty-one samples were septic based on positive culture. RLUs were higher in septic effusions for filtered and native effusions compared with sterile effusions. The use of a filter reduced cell counts. In filtered samples incubated for 30 minutes before testing, the sensitivity and specificity of the luminometer for diagnosis of infection in cavitary effusions were 81% and 82%, respectively, using a cutoff of 12,202 RLUs.

Conclusions

The luminometer kit evaluated in this study represents a viable screening tool for diagnosis of septic cavitary effusions and could be used in conjunction with other POC diagnostics to support the rapid diagnosis of infection.

目的评估基于兽医照护点（POC）发光仪的试剂盒诊断猫狗脓毒性腹腔或胸腔积液的灵敏度和特异性：2020年1月至2021年7月期间进行的前瞻性研究：动物无菌腹腔穿刺术或胸腔穿刺术收集的48只自然腹腔或胸腔积液动物：根据制造商的说明和不同的培养期，将流出物样本分成过滤样本（使用 10 微米过滤器）和未过滤样本，并使用 POC 仪器进行分析。此外，还在标准琼脂平板和血琼脂平板上对样本进行有氧培养。在样品中加入专有试剂，使细菌 ATP 产生生物荧光，由发光仪检测。记录生物发光值（相对光单位 [RLUs]），并与培养板上是否有细菌生长进行比较。记录原生和过滤流出物样本中的有核细胞计数：根据阳性培养结果，21 份样本为败血症样本。与无菌流出物相比，化脓性流出物中过滤流出物和原生流出物的 RLU 值更高。使用过滤器降低了细胞计数。在检测前培养 30 分钟的过滤样本中，以 12,202 RLUs 为临界值，发光计诊断腔积液感染的灵敏度和特异度分别为 81% 和 82%：结论：本研究评估的发光仪试剂盒是诊断脓腔积液的可行筛查工具，可与其他 POC 诊断方法结合使用，支持感染的快速诊断。

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引用次数: 0

Recurrent episodes of oral mite anaphylaxis in a dog 一只狗反复发作口腔螨过敏性休克。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-02-27 DOI: 10.1111/vec.13371

Michelle K. Beehler DVM, Meagan R. Painter DVM, DACVD, Courtney M. Peck DVM, DACVECC

Objective

To describe the clinical presentation and response to management of a dog with presumed oral mite anaphylaxis.

Case Summary

A 2-year-old male intact Golden Retriever was evaluated for a history of recurrent anaphylactic episodes. Over a period of 19 months, the dog had a total of 8 anaphylactic episodes that occurred in 2 different residences within the same state. The episodes most commonly resulted in vomiting and labored breathing, but the dog developed ascites, hypotension, and gall bladder wall edema during the most severe episodes. Serological testing demonstrated high immunoglobulin E levels to storage mites (SMs), specifically Tyrophagus SM. The dog's kibble was transitioned to being stored in small quantities in airtight containers in the freezer. At the time of publication, the dog has not had an anaphylactic reaction since making this change 1 year ago.

New or Unique Information Provided

Based on a literature search and to the best of the authors’ knowledge, this is the first time that SMs have been associated with severe recurrent anaphylaxis in a dog.

目的：描述一只患有假定性口腔螨过敏性休克的犬的临床表现和治疗反应：病例摘要：对一只两岁大的雄性完整金毛寻回犬进行了评估，该犬有反复过敏性发作的病史。在 19 个月的时间里，该犬在同一州的两个不同住所共发生了 8 次过敏反应。发作时最常见的症状是呕吐和呼吸困难，但在最严重的一次发作中，该犬出现了腹水、低血压和胆囊壁水肿。血清学检测显示，该犬对贮存螨（SM），特别是酪螨SM的免疫球蛋白E水平很高。该犬的狗粮转为少量存放在冷冻室的密闭容器中。截至本报告发表时，自 1 年前做出这一改变以来，该犬未出现过敏反应：根据文献检索，就作者所知，这是 SM 首次与狗的严重复发性过敏性休克有关。

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引用次数: 0

Comparison of plasma l-lactate between jugular and cephalic veins in healthy and systemically ill horses using a point-of-care device 使用护理点装置比较健康马匹和全身患病马匹颈静脉和头静脉血浆中的乳酸含量。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-02-27 DOI: 10.1111/vec.13364

Adrienne D. Rhodes DVM, Pamela A. Wilkins DVM, MS, PhD, DACVIM, DACVECC, Annette M. McCoy DVM, MS, PhD, DACVS

Objective

To compare plasma l-lactate (LAC) values between samples collected from jugular and cephalic venipuncture in healthy horses and systemically ill horses.

Design

Prospective, experimental study.

Setting

Large animal university teaching hospital.

Animals

Thirty healthy adult university-owned horses and 43 client-owned horses presenting to the large animal hospital for elective surgical procedures or for emergent medical evaluation of systemic illness.

Interventions

Blood samples were collected from the jugular vein (JV) and cephalic vein (CV) and placed in EDTA blood tubes prior to any medical therapy. LAC values were obtained with a handheld lactate meter at the time of blood collection.

Measurements and Main Results

LAC was higher in CV samples than JV samples in healthy horses (P < 0.001); however, all values were within the normal reference range. Similarly, LAC was higher in CV samples than JV samples in systemically ill horses (P < 0.001), but the median JV value was within normal reference range (1.9 mmol/L [17.1 mg/dL]), while the median CV value was outside the normal reference range (2.9 mmol/L [26.1 mg/dL]).

Conclusions

The CV is an alternative venipuncture site for assessing plasma LAC if the JV is not accessible or to preserve the JV for subsequent catheterization. However, in ill horses, the CV value may be outside the reference range when the corresponding JV value would have been within the reference range.

目的比较健康马匹和全身患病马匹颈静脉穿刺和头静脉穿刺采集的血浆乳酸（LAC）值：设计：前瞻性实验研究：动物30匹健康的大学成年马和43匹客户拥有的马，这些马到大型动物医院进行选择性外科手术或因全身性疾病进行紧急医疗评估：干预措施：在进行任何药物治疗之前，从颈静脉（JV）和头静脉（CV）采集血液样本，并将其置于EDTA血管中。在采血时使用手持式乳酸测量仪获得 LAC 值：测量结果和主要结果：在健康马匹中，CV 样本的乳酸浓度高于 JV 样本（P如果无法进入JV，或为了保留JV以便随后进行导管插入，CV是评估血浆乳酸浓度的替代静脉穿刺部位。然而，在患病马匹中，当相应的JV值在参考范围内时，CV值可能会超出参考范围。

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引用次数: 0

Lisdexamfetamine dimesylate (Vyvanse) toxicosis in a dog 一只狗的二美沙酮利司他明（Vyvanse）中毒症。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-02-27 DOI: 10.1111/vec.13370

Danielle M. Martindale DVM, Jenica L. Haraschak MS, DVM, DACVECC, Andrew J. Thiel DVM, Jonathan P. Samuelson MS, DVM, DACVP, John P. Buchweitz PhD, DABT

Objective

To describe the presentation, management, and postmortem examination findings in a dog with confirmed lisdexamfetamine dimesylate (LDX) toxicosis.

Case Summary

A 3-year-old female neutered mixed breed dog initially presented with neurological signs suspected to be secondary to LDX toxicosis. The dog was treated as typical for amphetamine toxicoses but developed severe respiratory and cardiovascular signs throughout their hospitalization. The progression of the cardiopulmonary signs led to cardiopulmonary arrest, for which CPR was unsuccessful. Postmortem examination exhibited severe hemorrhage throughout multiple organ systems. Toxicology testing confirmed the presence of unaltered LDX and its metabolite, amphetamine.

New or Unique Information Provided

This is the first case report documenting a severe progression of clinical signs and postmortem examination findings in a case of confirmed LDX toxicosis in a dog. Although the patient did not survive treatment, postmortem examination and microscopic evaluation of tissues allowed visualization of the extent of systemic pathophysiology. With prompt treatment, the prognosis of amphetamine toxicosis in dogs is generally considered good; however, this case report demonstrates a severe case in which even prompt and appropriate treatment did not prevent mortality. This suggests a need to establish negative prognostic indicators for which to monitor in cases of amphetamine toxicosis. Finally, this report is also unique in the fact that the LDX toxicosis was confirmed using a toxicological analysis technique not previously described clinically in dogs.

目的：描述一只确诊患有利眠宁（LDX）中毒症的 3 岁雌性混种犬的表现、处理方法和尸检结果：病例摘要：一只 3 岁的雌性阉割混种犬最初出现神经症状，怀疑是继发性 LDX 中毒。该犬接受了典型的苯丙胺中毒治疗，但在住院期间出现了严重的呼吸和心血管症状。心肺症状的发展导致心肺骤停，心肺复苏未能成功。死后检查显示多个器官系统严重出血。毒理学检测证实，死者体内含有未经改变的 LDX 及其代谢物苯丙胺：这是第一份病例报告，记录了一例确诊为 LDX 中毒的狗的临床症状和尸检结果的严重恶化。虽然患者未能在治疗中存活下来，但通过尸检和组织显微镜评估，可以看到全身病理生理学的程度。在及时治疗的情况下，犬苯丙胺中毒症的预后通常被认为是良好的；然而，本病例报告显示，在一个严重的病例中，即使进行了及时和适当的治疗也无法避免死亡。这表明有必要确定一些阴性预后指标，以便对苯丙胺中毒病例进行监测。最后，本报告的独特之处还在于，LDX 中毒是通过一种毒理学分析技术得到确认的，而这种技术以前从未在狗的临床中应用过。

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引用次数: 0

The use of a kaolin-based hemostatic dressing to attenuate bleeding in dogs: A series of 4 cases 使用高岭土止血敷料减轻狗的出血症状：4 例系列病例。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-02-26 DOI: 10.1111/vec.13361

Andrea Huther DVM, Thomas H. Edwards DVM, MS, DACVECC, Ericka L. Jaramillo DVM, James T. Giles III DVM, MS, DACVS, Sarah K. Israel DVM, DACVS, Michael Mison DVM, DACVS, Lisbeth Ambrosius DVM, MS, DACVIM, Teresa Kaiser DVM, Guillaume L. Hoareau DVM, PhD, FCCM, DACVECC, DECVECC

Objective

To describe the use of a synthetic hemostatic dressing, QuikClot Combat Gauze (QCG), in dogs with bleeding wounds.

Case Series Summary

Two dogs presented with bleeding traumatic wounds, and QCG was used to achieve hemostasis during stabilization of these dogs. In the other 2 dogs, QCG was used to help attenuate bleeding associated with a surgical procedure.

New or Unique Information Provided

While hemostatic dressings have been widely studied and used in human medicine, there is minimal information on the use and efficacy of these hemostatic dressings in veterinary medicine. This case series describes the use of QCG in dogs with hemorrhaging wounds. QCG could be a valuable resource in veterinary emergency and critical care settings.

目的：描述一种合成止血敷料 QuikClot Combat Gauze（QCG）在犬出血伤口中的应用：描述合成止血敷料 QuikClot Combat Gauze (QCG) 在犬类出血伤口中的使用情况。病例系列摘要：两只犬的外伤伤口出血，在稳定伤口时使用 QCG 止血。提供的信息新颖独特：虽然止血敷料在人类医学中得到了广泛的研究和使用，但有关这些止血敷料在兽医学中的使用和疗效的信息却少之又少。本系列病例介绍了 QCG 在犬出血伤口中的应用。QCG 可以成为兽医急诊和重症监护中的宝贵资源。

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引用次数: 0

Evaluation of B-lines with 2 point-of-care lung ultrasound protocols in cats with radiographically normal lungs 用两种护理点肺部超声波方案对肺部影像学正常的猫进行 B 线评估。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-02-26 DOI: 10.1111/vec.13360

Manon Rigot DMV, IPSAV, Søren R. Boysen DVM, DACVECC, Isabelle Masseau DMV, PhD, DACVR, Jo-Annie Letendre DMV, DACVECC

Objective

To compare 2 point-of-care lung ultrasound (LUS) protocols for quantification of B-lines in cats without evidence of respiratory disease based on history, physical examination, and thoracic radiography.

Design

Prospective observational study.

Setting

Single center, veterinary teaching hospital.

Animals

Fifty-seven cats without respiratory disease based on history, physical examination, and thoracic radiographs.

Interventions

All cats had 2 point-of-care LUS protocols performed bilaterally: a regional protocol (veterinary bedside lung ultrasound evaluation [VetBLUE]) and a more comprehensive vertical sweeping (VS) protocol. The total number of B-lines per cat, number of sites with B-lines, and maximal number of B-lines at each site were recorded and compared.

Measurements and Main Results

Ten cats (18%) had at least 1 B-line identified with VetBLUE, versus 29 (51%) with VS. Comparing protocols, VS had a statistically higher total number of B-lines per cat, higher number of sites with B-lines, and higher maximal number of B-lines per site. B-lines that were too numerous to count were identified at a single location in 1 cat with VetBLUE and 2 cats with VS. A maximum of 3 B-lines were identified at all other positive sites regardless of the protocol used. On average, it took 1.79 times longer to complete VS bilaterally compared to VetBLUE (median [interquartile range]: 140 [33] and 78 [14] s, respectively) (P = 0.001).

Conclusions

This study demonstrates it is not uncommon to identify a single or even multiple B-lines in 1 or several sites on LUS in cats deemed to be clinically free of respiratory pathology—essential knowledge when using LUS as a screening test and to monitor intrathoracic lesions. In cats asymptomatic for respiratory disease, VS generally identifies more B-lines than VetBLUE, likely because it assesses a larger lung surface area. The sonographic identification of B-lines should be interpreted considering the LUS protocol used, history, and other diagnostics to determine their clinical significance.

目的：比较两种护理点肺部超声检查（LUS）方案，以便根据病史、体格检查和胸片对无呼吸道疾病证据的猫进行 B 线定量：比较两种基于病史、体格检查和胸部 X 射线检查的护理点肺部超声波 (LUS) 方案，以量化无呼吸道疾病证据的猫的 B 线：设计：前瞻性观察研究：单中心兽医教学医院：动物：57 只根据病史、体格检查和胸部 X 光片检查无呼吸道疾病的猫：所有猫咪均接受了 2 项双侧护理点 LUS 方案：区域性方案（兽医床旁肺部超声评估 [VetBLUE]）和更全面的垂直扫查 (VS) 方案。记录并比较了每只猫的 B 线总数、有 B 线的部位数和每个部位的最大 B 线数：使用 VetBLUE 时，有 10 只猫（18%）至少发现了 1 条 B 线，而使用 VS 时有 29 只猫（51%）发现了 1 条 B 线。比较两种方案，VS 方案每只猫的 B 线总数、有 B 线的部位数和每个部位的最大 B 线数均高于 VS 方案。在使用 VetBLUE 的 1 只猫和使用 VS 的 2 只猫中，在单个位置发现了无法计数的 B 线。无论使用哪种方案，在所有其他阳性部位都最多发现了 3 条 B 线。与 VetBLUE 相比，完成双侧 VS 平均需要 1.79 倍的时间（中位数[四分位间范围]分别为 140 [33] 秒和 78 [14] 秒）（P = 0.001）：本研究表明，在临床上被认为没有呼吸道病变的猫咪中，在 LUS 的一个或多个部位发现单条甚至多条 B 线的情况并不少见，这是将 LUS 用作筛查检验和监测胸腔内病变时的必要知识。在无呼吸道疾病症状的猫中，VS 通常比 VetBLUE 能识别出更多的 B 线，这可能是因为 VS 评估的肺表面积更大。在解释声像图识别出的 B 线时，应考虑所使用的 LUS 方案、病史和其他诊断，以确定其临床意义。

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引用次数: 0

Seizures in 3 juvenile dogs after intravenous anesthetic drug withdrawal during weaning from mechanical ventilation suspected to be a sign of iatrogenic withdrawal syndrome 在机械通气断奶期间，3 只幼犬在静脉注射麻醉药物后出现癫痫发作，怀疑是先天性戒断综合征的征兆。

IF 1.3 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care

Pub Date : 2024-02-26 DOI: 10.1111/vec.13366

Kaitlyn Dreese VMD, Kellyann Murphy DVM, Jasper Burke VMD, Deborah C. Silverstein DVM, DACVECC

Objective

To describe seizure activity in juvenile dogs successfully weaned from long-term mechanical ventilation.

Case Series Summary

Three juvenile dogs (all approximately 3 months old) underwent long-term mechanical ventilation with IV anesthesia for suspected noncardiogenic pulmonary edema. Within 24 hours of extubation and within 10 hours of discontinuing midazolam continuous infusions, all dogs experienced seizures, which is 1 sign of iatrogenic withdrawal syndrome. Each dog was treated with an anticonvulsant protocol, and none experienced seizures after being discharged.

New or Unique Information Provided

Each dog received IV anesthesia, including fentanyl, dexmedetomidine, midazolam, and propofol, during mechanical ventilation and subsequently experienced seizures after successful weaning from mechanical ventilation. Juvenile dogs may be at risk for seizures after weaning from mechanical ventilation and IV anesthesia. Neurological monitoring and further research into an appropriate weaning protocol may prove beneficial in juvenile dogs requiring prolonged anesthesia.

目的：描述成功脱离长期机械通气的幼犬的癫痫活动：病例系列摘要：三只幼犬（均约 3 个月大）因疑似非心源性肺水肿接受了静脉麻醉的长期机械通气。在拔管后 24 小时内和停止咪达唑仑持续输注后 10 小时内，所有狗都出现了癫痫发作，这是先天性戒断综合征的一种表现。每只狗都接受了抗惊厥治疗，出院后无一癫痫发作：每只狗都在机械通气期间接受了静脉麻醉，包括芬太尼、右美托咪定、咪达唑仑和丙泊酚，随后在成功脱离机械通气后出现癫痫发作。幼犬在断开机械通气和静脉麻醉后可能有癫痫发作的风险。对需要长时间麻醉的幼犬进行神经监测并进一步研究适当的断奶方案可能会对它们有益。

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引用次数: 0