Pub Date : 2024-07-02DOI: 10.1038/s41684-024-01399-y
Alexandra Le Bras
{"title":"A new approach for Drosophila cardiac analysis","authors":"Alexandra Le Bras","doi":"10.1038/s41684-024-01399-y","DOIUrl":"10.1038/s41684-024-01399-y","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 7","pages":"171-171"},"PeriodicalIF":5.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.1038/s41684-024-01396-1
Charlotte Harrison
3R centers around the world are confronting the challenges of 3R implementation in animal research by sharing outcomes, resources and training with scientists.
世界各地的 3R 中心通过与科学家分享成果、资源和培训，应对在动物研究中实施 3R 的挑战。
{"title":"3R centers tap into the human mindset to bolster replacement, reduction and refinement uptake","authors":"Charlotte Harrison","doi":"10.1038/s41684-024-01396-1","DOIUrl":"10.1038/s41684-024-01396-1","url":null,"abstract":"3R centers around the world are confronting the challenges of 3R implementation in animal research by sharing outcomes, resources and training with scientists.","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 7","pages":"166-169"},"PeriodicalIF":5.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41684-024-01396-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.1038/s41684-024-01404-4
Jorge Ferreira
{"title":"Using chemogenetics to reduce rat obesity","authors":"Jorge Ferreira","doi":"10.1038/s41684-024-01404-4","DOIUrl":"10.1038/s41684-024-01404-4","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 7","pages":"172-172"},"PeriodicalIF":5.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-24DOI: 10.1038/s41684-024-01406-2
Alexandra Le Bras
{"title":"Targeting senescence with SGLT2 inhibitors","authors":"Alexandra Le Bras","doi":"10.1038/s41684-024-01406-2","DOIUrl":"10.1038/s41684-024-01406-2","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 7","pages":"176-176"},"PeriodicalIF":5.9,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41684-024-01406-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-24DOI: 10.1038/s41684-024-01395-2
Kornelia Ellwanger, Julie A. Brill, Elke de Boer, Stephanie Efthymiou, Ype Elgersma, Marynelle Icmat, François Lecoquierre, Amanda G. Lobato, Manuela Morleo, Michela Ori, Ashleigh E. Schaffer, Antonio Vitobello, Sara Wells, Binnaz Yalcin, R. Grace Zhai, Marc Sturm, Birte Zurek, Holm Graessner, Eva Bermejo-Sánchez, Teresinha Evangelista, Nicoline Hoogerbrugge, Vincenzo Nigro, Rebecca Schüle, Alain Verloes, Han Brunner, Philippe M. Campeau, Paul Lasko, Olaf Riess
In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeutic interventions. Within Solve-RD, an EU-funded research project with the aim of solving large numbers of previously unsolved RDs, the European Rare Disease Models & Mechanisms Network (RDMM-Europe) has been established.
{"title":"Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)","authors":"Kornelia Ellwanger, Julie A. Brill, Elke de Boer, Stephanie Efthymiou, Ype Elgersma, Marynelle Icmat, François Lecoquierre, Amanda G. Lobato, Manuela Morleo, Michela Ori, Ashleigh E. Schaffer, Antonio Vitobello, Sara Wells, Binnaz Yalcin, R. Grace Zhai, Marc Sturm, Birte Zurek, Holm Graessner, Eva Bermejo-Sánchez, Teresinha Evangelista, Nicoline Hoogerbrugge, Vincenzo Nigro, Rebecca Schüle, Alain Verloes, Han Brunner, Philippe M. Campeau, Paul Lasko, Olaf Riess","doi":"10.1038/s41684-024-01395-2","DOIUrl":"10.1038/s41684-024-01395-2","url":null,"abstract":"In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeutic interventions. Within Solve-RD, an EU-funded research project with the aim of solving large numbers of previously unsolved RDs, the European Rare Disease Models & Mechanisms Network (RDMM-Europe) has been established.","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 7","pages":"161-165"},"PeriodicalIF":5.9,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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