Helicobacter pylori is a gram-negative, microaerophilic bacteria that lives in the stomach of most of the human population. Overview of novel alternatives utilizing common natural phytochemicals has been demonstrated as powerful tools in bringing down the bacterial levels, managing inflammation, and regulating the immune response. Vacha (Acorus calamus Linn. (Acoraceae)) is a traditional Indian medicinal plant used to cure various illnesses. Our study strongly supports the therapeutic use of Acorus calamus Linn. phytocompounds as a possible herb that can be considered to inhibit Helicobacter pylori. This study aimed to identify the phytochemicals of the Acorus calamus that can inhibit H.pylori. Here we are using in silico molecular docking approach by using bioinformatics tools. In conclusion, our study strongly supports the medicinal use of Acorus calamus Linn. phytocompounds as a possible herb that can be considered to inhibit Helicobacter pylori. Further research may be performed on the phytocompounds, shyobunone, and 2,3,5-trimethoxyamphetamine to determine the exact action mechanism and validate the obtained results further.
{"title":"Computational Approach Assessing the Antibacterial Activity of Acorus calamus Against Helicobacter pylori","authors":"","doi":"10.33263/lianbs124.091","DOIUrl":"https://doi.org/10.33263/lianbs124.091","url":null,"abstract":"Helicobacter pylori is a gram-negative, microaerophilic bacteria that lives in the stomach of most of the human population. Overview of novel alternatives utilizing common natural phytochemicals has been demonstrated as powerful tools in bringing down the bacterial levels, managing inflammation, and regulating the immune response. Vacha (Acorus calamus Linn. (Acoraceae)) is a traditional Indian medicinal plant used to cure various illnesses. Our study strongly supports the therapeutic use of Acorus calamus Linn. phytocompounds as a possible herb that can be considered to inhibit Helicobacter pylori. This study aimed to identify the phytochemicals of the Acorus calamus that can inhibit H.pylori. Here we are using in silico molecular docking approach by using bioinformatics tools. In conclusion, our study strongly supports the medicinal use of Acorus calamus Linn. phytocompounds as a possible herb that can be considered to inhibit Helicobacter pylori. Further research may be performed on the phytocompounds, shyobunone, and 2,3,5-trimethoxyamphetamine to determine the exact action mechanism and validate the obtained results further.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"202 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77001465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Dan, P. Dutta, Devender Kumar Sharma, A. Rout, S. Upadhyay, R. Kumari
More than one year since coronavirus disease 2019 was declared a deadly disease by World Health Organization, the deadly severe acute respiratory syndrome Coronavirus 2 continues to disrupt public life worldwide. Several nations have seen a two-wave design in revealed instances of COVID 19 pandemic, with a first wave of infection during early 2K20 followed by the ongoing second wave. An investigation of the predominance of COVID-19 in India from the first wave to the second wave was utilized to characterize critical contrasts, infection patterns, lethality, and therapeutic measures through extensive vaccination pan-India free of cost. The quantitative transmission brought about COVID-19, including meteorological boundaries and topographical locale information, was gathered using web search tools and available literature and substantiated by factual advanced numerical tools. Experimental information showed that the qualities of the infection impacts do change between the two-time frames. The examination between the first wave and second wave, where COVID-19 flare-ups were now turning out to be scourged, was contemplated. Contrasts in age reach and seriousness of the infection have been accounted for, albeit the relative qualities of the two waves remain to a great extent obscure. The present investigation recommends that variability in environmental temperature and moisture contents may not be the significant components influencing the COVID-19 mortality during different waves of infection. The second wave of COVID-19 is influencing a large portion of the world, and especially the middle age group person relies on the principal top.
{"title":"Infectivity, Morbidity, Emerged Variants of SARS-CoV-2 and Vaccination in Indian Perspectives from First Wave to Second Wave of COVID-19","authors":"S. Dan, P. Dutta, Devender Kumar Sharma, A. Rout, S. Upadhyay, R. Kumari","doi":"10.33263/lianbs123.087","DOIUrl":"https://doi.org/10.33263/lianbs123.087","url":null,"abstract":"More than one year since coronavirus disease 2019 was declared a deadly disease by World Health Organization, the deadly severe acute respiratory syndrome Coronavirus 2 continues to disrupt public life worldwide. Several nations have seen a two-wave design in revealed instances of COVID 19 pandemic, with a first wave of infection during early 2K20 followed by the ongoing second wave. An investigation of the predominance of COVID-19 in India from the first wave to the second wave was utilized to characterize critical contrasts, infection patterns, lethality, and therapeutic measures through extensive vaccination pan-India free of cost. The quantitative transmission brought about COVID-19, including meteorological boundaries and topographical locale information, was gathered using web search tools and available literature and substantiated by factual advanced numerical tools. Experimental information showed that the qualities of the infection impacts do change between the two-time frames. The examination between the first wave and second wave, where COVID-19 flare-ups were now turning out to be scourged, was contemplated. Contrasts in age reach and seriousness of the infection have been accounted for, albeit the relative qualities of the two waves remain to a great extent obscure. The present investigation recommends that variability in environmental temperature and moisture contents may not be the significant components influencing the COVID-19 mortality during different waves of infection. The second wave of COVID-19 is influencing a large portion of the world, and especially the middle age group person relies on the principal top.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73886432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
It has been estimated that by 2050, the world’s population could exceed 9 billion. Increased population results in hampering food availability. Nanoscale nutrients have been considered new entrants to modern agriculture. Herein, we are the first to report on the effects of combined application(at field scale) of nanoscale nutrients of zinc (N-ZnO), calcium (N-CaO), and silica (N-SiO2) on the growth and yield of groundnut. The sol-gel method was used to prepare the nanoscale nutrients and was characterized using the techniques such as scanning electron microscopy (SEM), and dynamic light scattering. Significant Pod yield (2934.44Kg/ha) was recorded with the combined application of nanoscale nutrients @ 350 ppm and was 18 % over bulk nutrients (2472.78 kg/ha). Increased pod yield may be ascribed to an increase in SCMR (8.5% higher over bulk nutrients), leaf area, total dry matter besides peg to pod ratio (4.7% over bulk nutrients), and test weight (27% over bulk nutrients). Overall, the better performance of groundnut has been accredited for the combined application of nanoscale nutrients @ 350 ppm. The obtained results point out that the application of nanoscale nutrients in agriculture for enhanced and sustained is promising.
{"title":"Combined Effect of Nanoscale Nutrients (Zinc, Calcium, and Silica) on Growth and Yield of Groundnut (Arachis hypogaea L.)","authors":"","doi":"10.33263/lianbs123.084","DOIUrl":"https://doi.org/10.33263/lianbs123.084","url":null,"abstract":"It has been estimated that by 2050, the world’s population could exceed 9 billion. Increased population results in hampering food availability. Nanoscale nutrients have been considered new entrants to modern agriculture. Herein, we are the first to report on the effects of combined application(at field scale) of nanoscale nutrients of zinc (N-ZnO), calcium (N-CaO), and silica (N-SiO2) on the growth and yield of groundnut. The sol-gel method was used to prepare the nanoscale nutrients and was characterized using the techniques such as scanning electron microscopy (SEM), and dynamic light scattering. Significant Pod yield (2934.44Kg/ha) was recorded with the combined application of nanoscale nutrients @ 350 ppm and was 18 % over bulk nutrients (2472.78 kg/ha). Increased pod yield may be ascribed to an increase in SCMR (8.5% higher over bulk nutrients), leaf area, total dry matter besides peg to pod ratio (4.7% over bulk nutrients), and test weight (27% over bulk nutrients). Overall, the better performance of groundnut has been accredited for the combined application of nanoscale nutrients @ 350 ppm. The obtained results point out that the application of nanoscale nutrients in agriculture for enhanced and sustained is promising.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90185411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thermostability is a crucial property of biological materials, especially in the case of their potential application in materials science, including such novel directions as Extreme Biomimetics. This approach includes research at high temperatures without destroying the 3D structure of selected biological materials that allow the development of novel nanostructured composites. Consequently, this article presents an overview of the characterization of such biomaterials as chitin, chitosan, spongin, collagen, keratin, silk, byssus, and conchiolin in the contest of their structure and thermostability with respect to future potential applications. The review also highlights the instrumental techniques used for thermal analysis of materials – thermogravimetric methods. The review covered the latest achievements in the issue of thermostability research of natural, renewable materials, and the information presented in this paper may be valuable in future practical studies.
{"title":"Thermostability of Selected Biological Materials","authors":"","doi":"10.33263/lianbs123.088","DOIUrl":"https://doi.org/10.33263/lianbs123.088","url":null,"abstract":"Thermostability is a crucial property of biological materials, especially in the case of their potential application in materials science, including such novel directions as Extreme Biomimetics. This approach includes research at high temperatures without destroying the 3D structure of selected biological materials that allow the development of novel nanostructured composites. Consequently, this article presents an overview of the characterization of such biomaterials as chitin, chitosan, spongin, collagen, keratin, silk, byssus, and conchiolin in the contest of their structure and thermostability with respect to future potential applications. The review also highlights the instrumental techniques used for thermal analysis of materials – thermogravimetric methods. The review covered the latest achievements in the issue of thermostability research of natural, renewable materials, and the information presented in this paper may be valuable in future practical studies.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78904779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study mainly deals with preparing multifunctional bio-nano composite films composed of carboxymethyl cellulose and pectin moieties incorporated with zinc oxide NPs produced by wet casting techniques. The zinc oxide NPs were produced by the green synthetic route. The physiological properties of synthesized zinc oxide NPs were well characterized using U.V-Visible spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, and a particle size analyzer. The morphological properties of the films blended with Zinc oxide NPs were thoroughly characterized using Scanning electron microscopy (SEM), and their antimicrobial activity studies were also performed by disc diffusion method against E. Coli, Bacillus, Streptococcus aureus, Klebsiella. The effects of CMC and Pectin were tested for their water vapor transmission rate (WVTR), and the mechanical properties of the ZnO NPs blended with bio-nano composites were also evaluated. The bio-nano composite films showed that good water vapor barrier capacity, incorporating Zinc Oxide NPs into the biofilms, further improves the additional mechanical properties and antimicrobial properties. The above prepared ZnO NPs based bio-nano composite films could be used for packaging applications.
{"title":"Multifunctional Bio-Nanocomposite Films of Carboxymethyl Cellulose and Pectin with Incorporated Zinc Oxide Nanoparticles","authors":"","doi":"10.33263/lianbs123.085","DOIUrl":"https://doi.org/10.33263/lianbs123.085","url":null,"abstract":"This study mainly deals with preparing multifunctional bio-nano composite films composed of carboxymethyl cellulose and pectin moieties incorporated with zinc oxide NPs produced by wet casting techniques. The zinc oxide NPs were produced by the green synthetic route. The physiological properties of synthesized zinc oxide NPs were well characterized using U.V-Visible spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, and a particle size analyzer. The morphological properties of the films blended with Zinc oxide NPs were thoroughly characterized using Scanning electron microscopy (SEM), and their antimicrobial activity studies were also performed by disc diffusion method against E. Coli, Bacillus, Streptococcus aureus, Klebsiella. The effects of CMC and Pectin were tested for their water vapor transmission rate (WVTR), and the mechanical properties of the ZnO NPs blended with bio-nano composites were also evaluated. The bio-nano composite films showed that good water vapor barrier capacity, incorporating Zinc Oxide NPs into the biofilms, further improves the additional mechanical properties and antimicrobial properties. The above prepared ZnO NPs based bio-nano composite films could be used for packaging applications.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80578334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Smart sensors integrated with artificial intelligence (AI) have brought pragmatic solutions to many networking sectors, enterprises, and as well as government organizations around the world. This review highlights linking Internet of Things (IoT) technology coupled with artificial intelligence with heart monitoring to make it more personalized and timelier by allowing devices to communicate with one another. Most heart attacks result in the death of a patient much prior patient seeking treatment. The conventional and established treatment strategy is passive, in which patients initiate contact with healthcare providers. As a result, if the patient is not in a state to contact healthcare professionals while facing critical symptoms of cardiovascular disorders, they are unlikely to call for help. The potential prospective of AI in learning information contained in human heart rate monitoring for boosting an individual's performance is briefly outlined in this research.
{"title":"Recent Advancements in Artificial Intelligence Assisted Monitoring of Heart Abnormalities and Cardiovascular Diseases: A Review","authors":"","doi":"10.33263/lianbs123.089","DOIUrl":"https://doi.org/10.33263/lianbs123.089","url":null,"abstract":"Smart sensors integrated with artificial intelligence (AI) have brought pragmatic solutions to many networking sectors, enterprises, and as well as government organizations around the world. This review highlights linking Internet of Things (IoT) technology coupled with artificial intelligence with heart monitoring to make it more personalized and timelier by allowing devices to communicate with one another. Most heart attacks result in the death of a patient much prior patient seeking treatment. The conventional and established treatment strategy is passive, in which patients initiate contact with healthcare providers. As a result, if the patient is not in a state to contact healthcare professionals while facing critical symptoms of cardiovascular disorders, they are unlikely to call for help. The potential prospective of AI in learning information contained in human heart rate monitoring for boosting an individual's performance is briefly outlined in this research.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81346738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The iron nanoparticles were green synthesized from the leaf extract of Khaya senegalensis, and ferric chloride (FeCl3) was utilized as a metal -precursor. The synthesized Nanoparticles were characterized using UV-Visible Spectophotomety, FTIR, SEM, and EDX and XRD. The UV-visible analysis results confirmed the formation of Nanoparticles. FTIR identifies the functional groups present, SEM coupled with EDX shows the morphology of (FeNPS) as spherical granular with no well-defined morphology. XRD analysis showed face-centered cubic (FCC) structures with an average particle size of 75.31nm. The FeNPS showed significant antibacterial and antifungal activities of the synthesized drugs (nanoparticles) when tested against Escherichia coli, Pseudomonas aeruginosa (Gram-negative), Staphylococcus aureus, Klebsiella pneumonia (Gram-positive) bacteria’s and two fungi Aspergillusniger and Candida—using augumentin and fulcin as control drugs.
{"title":"Green Synthesis and Characterization of Iron Nanoparticles from the Leaf Extract of Khaya senegalensis (Mahogany) and its Antimicrobial Activity","authors":"","doi":"10.33263/lianbs123.086","DOIUrl":"https://doi.org/10.33263/lianbs123.086","url":null,"abstract":"The iron nanoparticles were green synthesized from the leaf extract of Khaya senegalensis, and ferric chloride (FeCl3) was utilized as a metal -precursor. The synthesized Nanoparticles were characterized using UV-Visible Spectophotomety, FTIR, SEM, and EDX and XRD. The UV-visible analysis results confirmed the formation of Nanoparticles. FTIR identifies the functional groups present, SEM coupled with EDX shows the morphology of (FeNPS) as spherical granular with no well-defined morphology. XRD analysis showed face-centered cubic (FCC) structures with an average particle size of 75.31nm. The FeNPS showed significant antibacterial and antifungal activities of the synthesized drugs (nanoparticles) when tested against Escherichia coli, Pseudomonas aeruginosa (Gram-negative), Staphylococcus aureus, Klebsiella pneumonia (Gram-positive) bacteria’s and two fungi Aspergillusniger and Candida—using augumentin and fulcin as control drugs.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85482862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
1-Aryl-2-mercapto-4-(phenyl/p-chlorophenyl)imidazoles (Ia-j) were condensed with monochloroacetic acid to give 1-aryl-4-(phenyl/p-chlorophenyl)imidazo-2-mercaptoacetic acid (IIa-j). These acids were subsequently cyclized with an acetic anhydride-pyridine mixture to give a new fused ring mesoionic 1-aryl-4-(phenyl/p-chlorophenyl)imidazo[2,1-b]thiazol-1-3-ones (IIIa-j). These compounds possess AID50 values ranging from 500 to 1000 mg kg-1, inhibit monoamineoxidase (32-68%), and succinate dehydrogenase (28-55%) in vitro at a concentration of 2×10-4 M, and provide 20-60% protection against pentylenetetrazole induced convulsions in mice.
{"title":"Synthesis of Mesoionic 1-aryl-4-(phenyl/p-chlorophenyl)imidazo[2,1-b]thiazol-4-ones and Study of their Monoamine Oxidase, Succinate Dehydrogenase Inhibitory, Anti-convulsant, and Antibacterial Activity","authors":"","doi":"10.33263/lianbs123.090","DOIUrl":"https://doi.org/10.33263/lianbs123.090","url":null,"abstract":"1-Aryl-2-mercapto-4-(phenyl/p-chlorophenyl)imidazoles (Ia-j) were condensed with monochloroacetic acid to give 1-aryl-4-(phenyl/p-chlorophenyl)imidazo-2-mercaptoacetic acid (IIa-j). These acids were subsequently cyclized with an acetic anhydride-pyridine mixture to give a new fused ring mesoionic 1-aryl-4-(phenyl/p-chlorophenyl)imidazo[2,1-b]thiazol-1-3-ones (IIIa-j). These compounds possess AID50 values ranging from 500 to 1000 mg kg-1, inhibit monoamineoxidase (32-68%), and succinate dehydrogenase (28-55%) in vitro at a concentration of 2×10-4 M, and provide 20-60% protection against pentylenetetrazole induced convulsions in mice.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86813227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper reveals the relevance of developing a technology for obtaining extracts of medicinal plant raw materials Adonis vernalis for its use as an individual drug or as part of a complex drug. Optimal indicators of extraction of biologically active substances of Adonis vernalis that affect the technological process, namely the particle size, the type of extractant, the size of the hydraulic module, and the extraction method, are established. Considering energy-intensive, technological, and design factors, the best option for the process to obtain the maximum yield of the target component was chosen, namely, the circulating extraction of Adonis vernalis flavonoids. Kinetic regularities of the extraction process are determined. Based on the selected mathematical model, it was checked for adequacy. Extraction constants are determined. The issues of selecting technological equipment for obtaining this extract with a high content of the target component are considered. The optimal parameters of the Extraction mode of Adonis vernalis herb are established: extractant – 70% Ethanol, the degree of grinding of raw materials – 1.0–2.0 mm, the ratio of raw materials-extractant – 1:15, the extraction method – circulation. Also, this development will expand the range of raw materials for drugs that have antioxidant activity.
{"title":"Development of Technology for Obtaining Herbal Extracts of Adonis Vernalis","authors":"","doi":"10.33263/lianbs123.078","DOIUrl":"https://doi.org/10.33263/lianbs123.078","url":null,"abstract":"This paper reveals the relevance of developing a technology for obtaining extracts of medicinal plant raw materials Adonis vernalis for its use as an individual drug or as part of a complex drug. Optimal indicators of extraction of biologically active substances of Adonis vernalis that affect the technological process, namely the particle size, the type of extractant, the size of the hydraulic module, and the extraction method, are established. Considering energy-intensive, technological, and design factors, the best option for the process to obtain the maximum yield of the target component was chosen, namely, the circulating extraction of Adonis vernalis flavonoids. Kinetic regularities of the extraction process are determined. Based on the selected mathematical model, it was checked for adequacy. Extraction constants are determined. The issues of selecting technological equipment for obtaining this extract with a high content of the target component are considered. The optimal parameters of the Extraction mode of Adonis vernalis herb are established: extractant – 70% Ethanol, the degree of grinding of raw materials – 1.0–2.0 mm, the ratio of raw materials-extractant – 1:15, the extraction method – circulation. Also, this development will expand the range of raw materials for drugs that have antioxidant activity.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90624865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biocompatible Ag2Onanoparticles have been developed using L-Cysteine biomolecule as a capping molecule via the elementary co-precipitation method resulting in a stable, efficient, and pure crystal phase of silver oxide nanoparticles at room temperature. Optical, structural, morphological, and compositional measurements indicated that L-Cysteine plays a crucial role in the synthesis because of the better surface passivation and stability of Ag2O nanoparticles. The face-centered cubic phase structure is evident from the XRD pattern, and the particle size was calculated using the Scherrer formula, which is obtained in the range of 50 nm and 76 nm. The present synthetic approach is simple, eco-friendly (non-toxic), and as obtained, silver oxide nanoparticles can be used for photocatalytic and display applications.
{"title":"Role of Capping Molecule L-Cysteine on Synthesis and Characterization of Silver Oxide (Ag2O) Nanoparticles by Co-Precipitation Method","authors":"","doi":"10.33263/lianbs123.080","DOIUrl":"https://doi.org/10.33263/lianbs123.080","url":null,"abstract":"Biocompatible Ag2Onanoparticles have been developed using L-Cysteine biomolecule as a capping molecule via the elementary co-precipitation method resulting in a stable, efficient, and pure crystal phase of silver oxide nanoparticles at room temperature. Optical, structural, morphological, and compositional measurements indicated that L-Cysteine plays a crucial role in the synthesis because of the better surface passivation and stability of Ag2O nanoparticles. The face-centered cubic phase structure is evident from the XRD pattern, and the particle size was calculated using the Scherrer formula, which is obtained in the range of 50 nm and 76 nm. The present synthetic approach is simple, eco-friendly (non-toxic), and as obtained, silver oxide nanoparticles can be used for photocatalytic and display applications.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83530437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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