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Role of Fluoxetine in primary Monosymptomatic Nocturnal enuresis. 氟西汀在原发性单症状性夜间遗尿中的作用。
Pub Date : 2022-06-01 DOI: 10.21608/mjmu.2022.103268.1045
M. Abdelazim, A. Abdelhalim, M. El-Kenawy, T. Helmy
Nocturnal enuresis is involuntary voiding that occurs exclusively at night, after most children have stopped. For the diagnosis of primary monosymptomatic enuresis, at least three episodes of bed wetting in a patient who has never been dry for more than six months are required (PME). Despite a 15 % annual maturation rate, 0.5 % of all instances continue throughout adulthood, with significant effects for self-esteem. Behavioral and motivational therapy, alarm aids, and pharmacotherapy have all been recommended as therapeutic options for PME. Desmopressin or antimuscarinics like propiverine or oxybutynin are the most common medical treatments for PME. Response failure to these medications is one of the issues in the management of PME. In recent literature, the influence of medicines that modulate serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), on urination has been reported. These findings show that SSRIs might be used to treat nocturnal enuresis without the dangerous cardiac arrhythmia that tricyclic antidepressants cause or the hyponatremia that long-term desmopressin therapy causes. The goal of our research was to look at the role of fluoxetine in the treatment of enuresis in children.
夜间遗尿是一种只在夜间发生的不自主排尿,在大多数儿童停止后。对于原发性单症状性遗尿症的诊断,至少有三次尿床发作的患者从未干过超过6个月(PME)。尽管年成熟率为15%,但0.5%的情况会持续整个成年期,这对自尊有显著影响。行为和动机疗法、报警辅助和药物疗法都被推荐作为经前症候群的治疗选择。去氨加压素或抗蛇毒素如丙胺或奥昔布宁是治疗经前症候群最常见的药物。对这些药物的反应失败是PME管理中的问题之一。在最近的文献中,已经报道了调节血清素水平的药物,如选择性血清素再摄取抑制剂(SSRIs)对排尿的影响。这些发现表明,SSRIs可用于治疗夜间遗尿,而不会引起三环抗抑郁药引起的危险心律失常或长期去氨加压素治疗引起的低钠血症。我们研究的目的是观察氟西汀在治疗儿童遗尿症中的作用。
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引用次数: 0
Study of Indices Comprising Surrogate Markers of Vitamin D Deficiency 维生素D缺乏替代指标的研究
Pub Date : 2022-06-01 DOI: 10.21608/mjmu.2022.122044.1055
R. Botros, Manal Aboshady, B. Mostafa
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引用次数: 0
Microbiological assessment of raw milk and dairy products with special reference to Escherichia coli and Staphylococcus aureus. 原料奶和乳制品的微生物学评估,特别涉及大肠杆菌和金黄色葡萄球菌。
Pub Date : 2022-04-10 DOI: 10.21608/mvmj.2022.125702.1108
Marwa Eltoukhy, Mohamed Abdel-hamid, M. El-sayed
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引用次数: 0
The impact of potable water salinity on human health 饮用水盐度对人体健康的影响
Pub Date : 2022-04-05 DOI: 10.21608/mvmj.2022.119472.1101
R. Mandour
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引用次数: 0
Immunotherapy forthyroid eye disesase 甲状腺眼病的免疫治疗
Pub Date : 2022-04-01 DOI: 10.21608/mjmu.2021.103779.1050
A. Shohieb, Nashat Shawky, A. Shoma
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引用次数: 1
Predictors of Weight Regain after Bariatric Surgery. 减肥手术后体重恢复的预测因素。
Pub Date : 2022-04-01 DOI: 10.21608/mjmu.2021.84164.1033
Ashraf M Shoma, Farra Amelia Binti Shah Reza Huzzieni, M. M. Mahmoud
For the group of people which is morbidly obese, bariatric surgery remains the most successful form of weight reduction method that is available nowadays. But the idea of weight regain is a risk for all patients after the bariatric surgery. The body weight regain is an important hindrance to many people after the bariatric operation. Hence, it gives a vast full of complications to occur in the future. The root causes for weight recurrence are highly variable, which includes socioeconomic status, physical, physiological, dietary, and pathological factors, which may also be procedure-specific. Little information is currently available about how to anticipate and treat all the patients who regain their former weight. The standard method would be to warn patients on the possibility of weight recovery and to be aware of the potential solutions if it happens. The management includes multidisciplinary counselling and requisite one or more revision or conversion surgeries. Mansoura Medical Journal (Official Journal of Mansoura Faculty of Medicine) pISSN: 1110-211X; eISSN: 2735-3990
对于病态肥胖的人群来说,减肥手术仍然是目前最成功的减肥方法。但对于所有接受减肥手术的患者来说,体重反弹的想法都是一种风险。体重反弹是许多人在减肥手术后的一个重要障碍。因此,它给未来带来了大量的并发症。体重复发的根本原因是高度可变的,包括社会经济地位,身体,生理,饮食和病理因素,也可能是特定的手术。目前关于如何预测和治疗所有恢复到原来体重的病人的信息很少。标准的方法是警告患者体重恢复的可能性,并在发生这种情况时意识到可能的解决方案。治疗包括多学科咨询和必要的一次或多次修正或转换手术。曼苏拉医学杂志(曼苏拉医学院官方杂志)pISSN: 1110-211X;eISSN: 2735 - 3990
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引用次数: 3
Pediatric Inflammatory Multisystem Syndrome, temporally associated with SARS-CoV-2 (PIMS-TS) 与SARS-CoV-2暂时相关的儿童炎症多系统综合征(PIMS-TS)
Pub Date : 2022-04-01 DOI: 10.21608/mjmu.2021.83074.1029
Firdaus Abdullah, Ashraf M Shoma, Ahmed Darwish
This essay will delve into the knowledge circling the new emerging disease after COVID-19 has spread over the whole world and it affects children for the most part. PIMS-TS symptoms overlapped with Kawasaki Disease (KD) which is hyperinflammatory and multiorgan involvement. PIMS-TS incidence is unknown as of date. Albeit little is known about this disease, reports had shown that this disease is prevalent in the region where KD is not a familiar disease while regions that are famous with KD reported no case of PIMS-TS. While some symptoms overlapped with KD, the difference now is PIMS-TS affect the child of all ages and have a quick and more severe progression of symptoms. Multiorgan involvement such as cardiac, renal, respiratory, haematology, gastrointestinal, neurology, and dermatology coincide with hyperinflammation shows that this disease needs to be attended under emergency cases. To treat PIMS-TS, many experts have shown the steps to manage it by using the culmination of previous KD treatment, the experience of adult COVID-19 treatment, and other types of paediatric hyperinflammatory treatment. Also to prevent other complications that accompany the syndrome needs to be addressed with supplementary therapy and follow-up is a compulsory as the syndrome is newly discovered. Mansoura Medical Journal (Official Journal of Mansoura Faculty of Medicine) pISSN: 1110-211X; eISSN: 2735-3990
本文将深入研究COVID-19在全球传播后围绕新出现的疾病的知识,它主要影响儿童。PIMS-TS症状与川崎病(KD)重叠,川崎病是一种高炎症和多器官受累的疾病。截至目前,PIMS-TS发病率尚不清楚。尽管对该病知之甚少,但有报道表明该病在KD不常见的地区流行,而以KD闻名的地区没有报告PIMS-TS病例。虽然有些症状与KD重叠,但现在的不同之处在于PIMS-TS影响所有年龄段的儿童,并且症状进展迅速且更严重。多器官受累,如心脏、肾脏、呼吸、血液学、胃肠道、神经病学和皮肤病学,同时伴有高炎症,这表明这种疾病需要在急诊病例中进行治疗。为了治疗PIMS-TS,许多专家通过利用以往KD治疗的成果、成人COVID-19治疗的经验以及其他类型的儿科高炎症治疗,展示了管理该病的步骤。此外,为了防止伴随该综合征的其他并发症,需要通过补充治疗来解决,并且由于该综合征是新发现的,因此必须进行随访。曼苏拉医学杂志(曼苏拉医学院官方杂志)pISSN: 1110-211X;eISSN: 2735 - 3990
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引用次数: 0
recent advances in imaging of acute ischemic stroke 急性缺血性脑卒中的影像学研究进展
Pub Date : 2022-04-01 DOI: 10.21608/mjmu.2021.84209.1030
A. Kandeel, Mahitab Ghonim, Ashraf M Shoma
The need for early accurate diagnosis of AIS has motivated the development of new advanced imaging techniques for the early diagnosis of the condition and the selection of patients who might present outside the window for systemic thrombolytic therapy. During the last decade, the state of art imaging techniques has developed for the imaging of patients with hyperacute stroke including both angiographic and perfusion imaging. The imaging modalities, which are in widespread use in primary stroke imaging include; computed tomography and magnetic resonance imaging. Imaging can be categorized into structural imaging, vascular imaging and perfusion imaging. Important signs of early stroke on brain CT include; insular ribbon sign, the hypedense artery sign, and the development of hypo-attenuation lesions. MRI is more sensitive than CT for the demonstration of these lesions especially diffusion weighted images which are currently the gold standard for the evaluation of the extent of infarct core. Susceptibility weighted images are highly sensitive for the demonstration of hyperacute bleed within the infarct. CT and MR angiography are highly sensitive for the demonstration of large vessel occlusion which is very important for selection of patients for endovascular treatment. Perfusion studies can be performed using CT or MRI and are showing an increasing role in the identification of salvageable brain tissue (penumbra) and target mismatch between hypoperf used volume and infarct core, an important criterion for selection of patient who might benefit from endovascular treatment.
早期准确诊断AIS的需求推动了新的先进成像技术的发展,以早期诊断病情,并选择可能出现在窗外的患者进行全身溶栓治疗。在过去的十年中,最先进的成像技术已经发展为超急性脑卒中患者的成像,包括血管造影和灌注成像。在原发性卒中成像中广泛使用的成像方式包括;计算机断层扫描和磁共振成像。成像可分为结构成像、血管成像和灌注成像。脑CT早期中风的重要征象包括;岛带状征,动脉高密度征,以及低衰减病变的发展。MRI对这些病变的显示比CT更敏感,尤其是弥散加权图像,目前弥散加权图像是评估梗死核心范围的金标准。敏感性加权图像对梗死内超急性出血的显示高度敏感。CT和MR血管造影对大血管闭塞的显示非常敏感,这对选择血管内治疗的患者非常重要。灌注研究可以使用CT或MRI进行,并且在识别可挽救的脑组织(半暗带)和低灌注容量与梗死核心之间的靶不匹配方面显示出越来越重要的作用,这是选择可能受益于血管内治疗的患者的重要标准。
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引用次数: 0
Could CAR-T cell therapy be promising agent in acute lymphoblastic leukemia? CAR-T细胞疗法能成为治疗急性淋巴细胞白血病的有效药物吗?
Pub Date : 2022-04-01 DOI: 10.21608/mjmu.2021.103500.1048
Omar khafagy, S. El-Ashwah, Ashraf M Shoma
Postoperative anal pain is one of the main adverse effects of surgical treatment of benign anorectal diseases and remains a distressing problem, for both patients and physicians. Postoperative pain control is important yet it remains an unresolved issue which causes patient dissatisfaction and negatively impact quality of life. This review article studied the analgesic effect of topical and oral metronidazole after benign anorectal surgery. Seven studies used oral metronidazole and six used topical metronidazole. The studies showed that post operative pain score of patients who had metronidazole by either route was significantly less than those in comparison groups. The pain score decreased at all the time points for both oral and topical metronidazole. Overall, the analgesic effect of oral metronidazole was inconsistent among published studies. When topical and oral metronidazole were compared the post operative pain score and analgesic consumption were lower in topical metronidazole than the oral group Mansoura Medical Journal (Official Journal of Mansoura Faculty of Medicine) pISSN: 1110-211X; eISSN: 2735-3990
术后肛门疼痛是良性肛肠疾病手术治疗的主要不良反应之一,对患者和医生来说都是一个困扰的问题。术后疼痛控制很重要,但它仍然是一个未解决的问题,引起患者的不满和负面影响生活质量。本文综述了良性肛肠手术后局部和口服甲硝唑的镇痛效果。七项研究使用口服甲硝唑,六项研究使用外用甲硝唑。研究显示,两种治疗方式下甲硝唑组患者术后疼痛评分均显著低于对照组。口服和外用甲硝唑的疼痛评分在所有时间点均下降。总的来说,口服甲硝唑的镇痛效果在已发表的研究中是不一致的。比较外用和口服甲硝唑组术后疼痛评分和镇痛药用量,外用甲硝唑组低于口服组。曼苏拉医学杂志(Mansoura Medical Journal of Mansoura Faculty of Medicine) pISSN: 1110-211X;eISSN: 2735 - 3990
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引用次数: 0
The effect of Almond and hazelnuts on rats exposed to hypercholesterolemia 杏仁和榛子对高胆固醇血症大鼠的影响
Pub Date : 2022-03-06 DOI: 10.21608/mvmj.2022.51572.1017
M. El-Adl
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引用次数: 1
期刊
Mansoura Veterinary Medical Journal
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