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2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)最新文献

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Feasibility study of a gradient coil for a dedicated and portable single-sided MRI system 专用便携式单面MRI系统中梯度线圈的可行性研究
D. Grau-Ruíz, J. Rigla, E. Diaz-Caballero, A. Nacev, A. Aguilar, P. Bellido, P. Conde, A. Gonzalez-Montoro, A. González, L. Hernández, A. Iborra, L. Moliner, M. Rodríguez-Álvarez, S. Sánchez, M. Seimetz, A. Soriano, L. Vidal, I. Weinberg, F. Sánchez, J. Benlloch
Magnetic Resonance Imaging (MRI) is a widely used technique to obtain images in different applications based on the nuclear magnetic renonance (NMR) phenomenon. Gradient coils are the responsible components for encoding the volume of interest (VOI). Linearity, inductance and resistance are taken in account to perform the gradient coil design. In this work, EM and thermal gradient coil properties are studied and two cooling system are presented to cool them. Finally, the gradient coils are tested in a biplanar permanent magnet system and a 2D phantom image is obtained.
磁共振成像(MRI)是一种基于核磁共振(NMR)现象获得图像的广泛应用技术。梯度线圈是负责编码感兴趣体积(VOI)的元件。在进行梯度线圈设计时,考虑了线性度、电感和电阻。本文研究了电磁和热梯度线圈的特性,并提出了两种冷却系统。最后,在双平面永磁系统中对梯度线圈进行了测试,得到了二维幻像。
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引用次数: 2
Preliminary study of quantitative X-ray spectral imaging with spectral deconvolution 光谱反褶积定量x射线光谱成像的初步研究
Sen Wang, Li Zhang, Xiaofei Xu, Dufan Wu
The degrading factors of photon counting detectors such as charge-sharing, K-escape, resulting in spectrum distortion, set the crucial limitation for its application in quantitative imaging. We present a method to eliminate the degrading factors by spectral deconvolution. Simulation study and experimental study were carried out to verify its effectiveness and robustness. In simulation study, the method can significantly reduce the bias between detected photon counts and the theoretical value, which implies the effectiveness. Poisson noise was added to test the robustness and we find the result shows no significant difference to noiseless result when up to 106 photons are detected. In experimental study, theoretical spectrum is not easily accessible, instead we verified the effectiveness by calculating the width of an aluminum plate based on Beer-Lambert Law, which is supposed to be consistent among the whole energy range. An improvement can be seen after deconvolution and the output shows a good agreement with simulation result. Furthermore, we simulated a CT reconstruction process using the proposed method and found the reconstructed μ fits the theoretical value very well, which manifests a promising potential in quantitative X-ray spectral imaging.
光子计数探测器的电荷共享、k逃逸等退化因素导致的光谱畸变是限制其在定量成像中的应用的关键因素。提出了一种利用光谱反褶积消除退化因素的方法。仿真研究和实验研究验证了该方法的有效性和鲁棒性。仿真研究表明,该方法能显著减小探测光子数与理论值之间的偏差,证明了该方法的有效性。加入泊松噪声来检验鲁棒性,当检测到106个光子时,结果与无噪声结果没有显著差异。在实验研究中,理论谱不容易获得,我们通过基于Beer-Lambert定律计算铝板的宽度来验证其有效性,该宽度在整个能量范围内应该是一致的。反卷积后的输出与仿真结果吻合较好。利用该方法模拟了CT的重建过程,结果表明重建的μ值与理论值吻合较好,在定量x射线光谱成像中具有广阔的应用前景。
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引用次数: 0
Prostate brachytherapy optimization using GPU accelerated simulated annealing and Monte Carlo dose simulation 基于GPU加速模拟退火和蒙特卡罗剂量模拟的前列腺近距离治疗优化
Konstantinos A. Mountris, J. Bert, D. Visvikis
Planning the radioactive seeds delivery during prostate brachytherapy is a critical part of the overall procedure. The planning process is time consuming and requires substantial user input and implication to ensure the optimal decision on the seeds' locations. Therefore efforts have been done to help in the decision making and minimize the overall planning required time, introducing automatic optimization techniques. The principal idea of these techniques is the construction and minimization of a cost function considering certain prescribed parameters. By minimizing the cost function, the optimal seeds distribution can be retrieved. Therefore a successful minimization algorithm has to be able to search randomly the given solution space and find the global minimum, escaping existing local minima. Pouliot J. et al. [1] have successfully adopt the simulated annealing (SA) technique in the treatment planning optimization ofprostate brachytherapy. This approach is able to obtain clinically acceptable seed distributions after 20000 iterations within 15 minutes, time duration which is acceptable for treatment planning purposes prior to operation. However, the dose calculation using standard protocols induces significant uncertainties and the optimization result is limited by the dose calculation accuracy. GGEMS-Brachy, a framework using GPU accelerated Monte Carlo (MC) methods has been proposed to address the limitations of current dosimetric protocols by Lemarechal Y. et al. [2]. Within this context one can produce a dose calculation of 2% uncertainty in 9.35s / 2.5s using one or four GPUs respectively. Our goal is to combine the MC dosimetry accuracy delivered by GGEMSBrachy with the optimization procedure of SA to improve the dosimetric outcome for intraoperative radiotherapy procedures. In addition, we propose a simple yet efficient modification in the SA algorithm [1] to further decrease the computational cost of the optimization process exploiting the GPU capabilities in order to facilitate the introduction of MC simulation in treatment planning optimization.
在前列腺近距离放射治疗中,放射性粒子的输送计划是整个过程的关键部分。规划过程是耗时的,需要大量的用户输入和暗示,以确保对种子位置的最佳决策。因此,通过引入自动优化技术,已经做出了帮助决策和最小化总体规划所需时间的努力。这些技术的主要思想是考虑某些规定参数的成本函数的构造和最小化。通过最小化代价函数,可以得到最优的种子分布。因此,一个成功的最小化算法必须能够在给定的解空间中随机搜索并找到全局最小值,从而避免现有的局部最小值。Pouliot等[1]成功地将模拟退火(SA)技术应用于前列腺近距离放射治疗的治疗方案优化。该方法能够在15分钟内迭代20000次后获得临床可接受的种子分布,这一时间长度对于术前的治疗计划是可以接受的。然而,使用标准方案进行剂量计算存在较大的不确定性,优化结果受到剂量计算精度的限制。Lemarechal Y.等人提出了使用GPU加速蒙特卡罗(MC)方法的ggem - brachy框架,以解决当前剂量测定方案的局限性[2]。在这种情况下,可以分别使用一个或四个gpu在9.35秒/ 2.5秒内产生2%不确定度的剂量计算。我们的目标是将GGEMSBrachy提供的MC剂量学准确性与SA的优化程序相结合,以改善术中放疗程序的剂量学结果。此外,我们对SA算法提出了一个简单而有效的修改[1],以进一步降低利用GPU能力优化过程的计算成本,从而促进在治疗计划优化中引入MC模拟。
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引用次数: 3
A new vertical JFET technology for the powering scheme of the ATLAS upgrade inner tracker 一种用于ATLAS升级内跟踪器供电方案的新型垂直场效应晶体管技术
P. Fernandez-Martínez, L. Ré, D. Flores, S. Hidalgo, D. Quirion, M. Ullán
The IMB-CNM (Barcelona) has developed a new vertical JFET (V-JFET) technology with the purpose of working as rad-hard switches in the HV powering scheme of the upgraded ATLAS tracker. The design of the new transistors draws upon a deep-trenched 3D technology to achieve vertical conduction and low switch-off voltage. These features prospect suitable radiation hardness for the application. The first V-JFET prototypes are now fabricated and characterized, with very promising results already meeting the application requirements. A compilation of the simulated and measured performance is shown in the contribution. To evaluate the radiation hardness, gamma irradiation has been performed and the main results are presented here.
IMB-CNM (Barcelona)已经开发了一种新的垂直JFET (V-JFET)技术,目的是在升级的ATLAS跟踪器的高压供电方案中作为抗雷达开关。新晶体管的设计利用深沟3D技术实现垂直传导和低关断电压。这些特点为应用提供了合适的辐射硬度。第一个V-JFET原型现在已经制造和表征,具有非常有希望的结果已经满足应用要求。在贡献中显示了模拟和测量性能的汇编。为了评估辐射硬度,进行了伽玛辐照,并给出了主要结果。
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引用次数: 1
Soft-errors in FPGAs at the SuperKEKB interaction point fpga在SuperKEKB交互点的软误差
R. Giordano, V. Izzo, S. Perrella, A. Aloisio
In February 2016, the SuperKEKB positron-electron high-luminosity collider of the KEK laboratory (Tsukuba, Japan) started being commissioned. A dedicated commissioning detector, named BEAST2, has been used to characterize beam backgrounds before the Belle2 detector is rolled into the beams and to provide tuning parameters for Monte Carlo simulations. BEAST2 consists of a fiberglass support structure and several subdetectors mounted onto it, including time projection chambers (TPCs) and He-3 tubes. In this work, we present direct measurements of radiation-induced single event upsets in a SRAM-based FPGA device installed in BEAST2 at a distance of ∼1 m from the beam interaction point. Our goal is to provide experimental results of the expected radiation-induced configuration upset rate and power consumption variation at Belle2 and at other experiments operating in similar radiation conditions. For this study, we designed a dedicated board hosting a Xilinx Kintex-7 325T FPGA without additional active components, in such a way to be able to decouple FPGA failures from those of other devices. During the commissioning of the collider, we periodically read back the FPGA configuration in order to detect errors and we logged the power consumption on the different power domains of the device. Currents for both electron and positron rings spanned a range between 50 and 500 mA, therefore providing data about the FPGA operation in different radiation conditions.
2016年2月,KEK实验室(日本筑波)的SuperKEKB正电子高亮度对撞机开始投入使用。在Belle2探测器进入光束之前,一个名为BEAST2的专用调试探测器已被用于表征光束背景,并为蒙特卡罗模拟提供调谐参数。BEAST2由玻璃纤维支撑结构和安装在其上的几个子探测器组成,包括时间投影室(tpc)和He-3管。在这项工作中,我们在距离光束相互作用点约1 m的距离上,在安装在BEAST2中的基于sram的FPGA器件中直接测量辐射引起的单事件扰动。我们的目标是提供在Belle2和在类似辐射条件下运行的其他实验中预期的辐射引起的配置破坏率和功耗变化的实验结果。在这项研究中,我们设计了一个专用板,托管Xilinx Kintex-7 325T FPGA,没有额外的有源组件,这样就能够将FPGA故障与其他设备的故障解耦。在对撞机调试期间,我们定期回读FPGA配置以检测错误,并记录设备不同功率域的功耗。电子环和正电子环的电流范围在50到500 mA之间,因此提供了FPGA在不同辐射条件下工作的数据。
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引用次数: 1
DECIMO: A simulation tool to explore next generation of detectors for synchrotron radiation applications DECIMO:用于探索同步辐射应用的下一代探测器的模拟工具
T. Johng-ay, P. Fajardo, T. Martin, C. Ponchut, P. Douissard, M. Ruat
This paper introduces the detector simulation code DECIMO under development at the ESRF as well as some of its first applications. The code is organized as a modular Python package designed to simulate in a relatively easy and efficient way the complete detection chains of future X-ray detectors for synchrotron radiation experiments. The core of the simulation engine is based on Monte Carlo techniques implemented as efficient C/C++ routines integrated in Python objects that are interconnected to build the simulation chains. The package has been used for a preliminary investigation of various new signal processing schemes intended to push the spatial resolution of small pixel hybrid detectors, including photon counting schemes with subpixel relocation features. The paper also introduces the ESOP figure of merit, a single value describing an equivalent pixel size specifically defined to compare in a convenient way the spatial resolution of different detectors.
本文介绍了ESRF正在开发的探测器模拟代码DECIMO以及它的一些初步应用。该代码组织为模块化Python包,旨在以相对简单和有效的方式模拟用于同步辐射实验的未来x射线探测器的完整检测链。仿真引擎的核心是基于蒙特卡罗技术实现的,作为集成在Python对象中的高效C/ c++例程,这些例程相互连接以构建仿真链。该包已用于各种新的信号处理方案的初步研究,旨在提高小像素混合探测器的空间分辨率,包括具有亚像素重新定位特征的光子计数方案。本文还介绍了ESOP优值,这是一个描述等效像素尺寸的单一值,专门用于比较不同探测器的空间分辨率。
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引用次数: 3
Integration of GBTx emulator with MUCH-XYTER and data processing board for CBM experiment GBTx仿真器与MUCH-XYTER及CBM实验数据处理板的集成
S. Mandal, J. Saini, S. Sau, A. Chakrabarti, Wojciech Zabolotny, S. Chattopadhyay, W. Muller
The Compressed Baryonic Matter (CBM) experiment is a part of the Facility for Antiproton and Ion Research (FAIR) at Darmstadt, Germany. The challenge in CBM experiment is to measure the particles generated in nuclear collisions with unprecedented precision and statistics. To capture the data from each collision a highly time synchronized fault tolerant self-triggered electronics is required for Data Acquisition (DAQ) system that can support high data rate (up to several TB/s). Basic readout chain for CBM consists of a front-end Application Specific Integrated Circuit (ASIC) also known as X-Y Time Energy Read-out (XYTER) ASIC, a radiation hardened high speed optical transceiver board with Gigabit Transceiver (GBTx) ASIC followed by a Data Processing Board (DPB) and First Level Event Selector Interface Board (FLIB). As the first step towards the development of the readout chain, FPGA prototypes of GBTx ASIC and XYTER ASIC also known as GBTx emulator and XYTER emulator are developed. GBTx chips are connected to the XYTER in the front end through Low Voltage Differential Signalling (LVDS) electrical line also known as E-link and in the back-end with DPB using optical fiber. In this work, an FPGA-based readout chain prototype comprising of XYTER emulator, GBTx emulator, and DPB is developed where control and configuration signal of XYTER will be sent from DPB through GBTx emulator. A Python script is written in the computer to generate the control information that will be transferred to DPB through Ethernet using IPBus protocol.
压缩重子物质(CBM)实验是德国达姆施塔特反质子和离子研究设施(FAIR)的一部分。CBM实验的挑战在于以前所未有的精度和统计量来测量核碰撞中产生的粒子。为了从每次碰撞中捕获数据,数据采集(DAQ)系统需要高度时间同步的容错自触发电子设备,该系统可以支持高数据速率(高达几TB/s)。CBM的基本读出链包括前端应用专用集成电路(ASIC),也称为X-Y时间能量读出(XYTER) ASIC,具有千兆收发器(GBTx) ASIC的抗辐射高速光收发器板,然后是数据处理板(DPB)和一级事件选择接口板(FLIB)。作为读出链开发的第一步,开发了GBTx ASIC和XYTER ASIC(也称为GBTx仿真器和XYTER仿真器)的FPGA原型。GBTx芯片在前端通过低压差分信号(LVDS)电线(也称为E-link)连接到XYTER,在后端使用光纤与DPB连接。在本工作中,开发了一个基于fpga的读出链原型,该原型由XYTER仿真器、GBTx仿真器和DPB组成,其中XYTER的控制和配置信号将从DPB通过GBTx仿真器发送。在计算机中编写Python脚本生成控制信息,这些信息将通过以太网使用IPBus协议传输到DPB。
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引用次数: 1
Towards better normalization using photopeak monitoring from phantom/patient data in positron emission tomography (PET) 利用正电子发射断层扫描(PET)中幻影/患者数据的光峰监测实现更好的规范化
M. Aykaç, V. Panin
It is essential to have properly tuned PET scanner and data correction methods to obtain accurate quantitative images. Quality control (QC) procedure ensures reproducible performance of a clinical PET scanner. The scope of this study is to observe the stability of a PET scanner by monitoring the 511keV photopeak during a phantom/patient scan at the crystal level. In addition, during the histogramming process of the listmode data, normalization including the crystal-based deadtime model can be implemented for accurate data correction. The method of peak monitoring could be used to adjust crystal sensitivity based on the exact condition of each crystal during the patient scan in the future. This would allow for a “personalized”, improved normalization, using data already available during the data acquisition.
正确调整PET扫描仪和数据校正方法以获得准确的定量图像是至关重要的。质量控制(QC)程序确保临床PET扫描仪的再现性能。本研究的范围是通过在晶体水平上监测幻影/患者扫描期间的511keV光峰来观察PET扫描仪的稳定性。此外,在listmode数据的直方图化过程中,可以实现包括基于晶体的死区时间模型在内的归一化,以实现准确的数据校正。在未来的病人扫描过程中,可以利用峰值监测的方法根据每个晶体的确切情况来调整晶体的灵敏度。这将允许“个性化”,改进规范化,使用数据采集期间已经可用的数据。
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引用次数: 0
Efficient positioning of silicon photomultipliers on large scintillation crystals 硅光电倍增管在大闪烁晶体上的有效定位
P. Menge, Kan Yang, Michael McLaughlin, B. Bacon
Silicon photomultipliers (SiPMs) are attractive replacements for photomultiplier tubes (PMTs). However, many radiation detector applications require large volumes of monolithic scintillator and correspondingly large numbers of SiPMs. When multiples of SiPMs are used, the dark count noise and cost increase proportionally with the surface area covered. When too few SiPMs are used, non-uniformity of light collection degrades the energy resolution of the detector. Strategic placement of a limited number of SiPMs on a large scintillator can reduce the number of SiPMs necessary and decrease the cost-to-performance ratio. Simulations and experiments have been performed to find general guidelines regarding optimal positioning of SiPMs on large NaI(Tl) crystal scintillators. For example, if the SiPMs are placed near edges and vertices on one cuboid face, the number of SiPMs necessary to achieve adequate energy resolution need only cover 40% or less of the light output face.
硅光电倍增管(SiPMs)是光电倍增管(pmt)极具吸引力的替代品。然而,许多辐射探测器应用需要大量的单片闪烁体和相应的大量sipm。当使用多个sipm时,暗计数、噪声和成本随覆盖面积成比例地增加。当使用的sipm太少时,光收集的不均匀性会降低探测器的能量分辨率。在大型闪烁体上战略性地放置有限数量的sipm可以减少所需sipm的数量并降低成本-性能比。通过模拟和实验,找到了在大型NaI(Tl)晶体闪烁体上sipm的最佳定位的一般准则。例如,如果sipm放置在一个长方体表面的边缘和顶点附近,则实现足够能量分辨率所需的sipm数量只需要覆盖40%或更少的光输出面。
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引用次数: 5
Investigation of electron multiplication effect in optical property modulation-based radiation detection method for PET 基于光学性质调制的PET辐射检测方法中电子倍增效应的研究
Li Tao, H. Daghighian, C. Levin
In this paper, we further explore the optical property modulation-based method for ionizing radiation photon detection in PET as a potential new direction to dramatically improve the coincidence time resolution. We compare the performance of three detector crystals for this method including two types of cadmium telluride (CdTe) crystals and one bismuth silicon oxide (BSO) crystal under high bias voltages up to 3500V. We first show that the induced current flow in the detector crystal determines the strength of the optical property modulation signal due to ionization. A larger resistivity is favorable for reducing the dark current (noise) in the crystal and facilitates the detection of weak optical property modulation signals. In addition, we show that BSO is a potential candidate detector material. When biased at 3500 V, it has comparable modulation signal sensitivity as CdTe biased at 1000V, but with higher resistivity (lower noise), larger 511 keV photon attenuation coefficient, lower price, better crystal surface finish quality, and less toxicity. By studying the dependence of modulation signal amplitude on crystal bias voltage, we show that the modulation signal amplitude (induced by both UV laser diode and Ge-68 source) is linearly proportional to crystal bias voltage with a linear fit R factor of around 0.95. The modulation signal amplitude induced by UV laser diode irradiation increases from 0% to 2% (normalized to the average signal level) for both CdTe and BSO under crystal bias voltage from 0V to 3500V. The modulation signal amplitude induced by Ge-68 irradiation increases from 0% to 12% for CdTe under crystal bias voltage from 0V to 1500 V, and increases from 0% to 10% for BSO under crystal bias voltage from 0V to 3500 V. Therefore the electron multiplication effect (with high crystal bias) shows promise to significantly boost the modulation signal amplitude with the ultimate goal to achieve single 511 keV photon detection.
本文进一步探索了基于光学性质调制的PET电离辐射光子探测方法,作为显著提高符合时间分辨率的潜在新方向。我们比较了这种方法的三种探测器晶体的性能,包括两种碲化镉(CdTe)晶体和一种氧化铋硅(BSO)晶体在高达3500V的高偏置电压下的性能。我们首先证明了探测器晶体中的感应电流决定了电离引起的光学性质调制信号的强度。较大的电阻率有利于降低晶体中的暗电流(噪声),有利于检测微弱的光学性质调制信号。此外,我们还证明了BSO是一种潜在的候选探测器材料。当偏置在3500 V时,其调制信号灵敏度与偏置在1000V时的CdTe相当,但具有更高的电阻率(更低的噪声)、更大的511 keV光子衰减系数、更低的价格、更好的晶体表面光洁度和更小的毒性。通过研究调制信号幅度与晶体偏置电压的关系,我们发现调制信号幅度(由UV激光二极管和Ge-68源诱导)与晶体偏置电压成线性正比,线性拟合R因子约为0.95。当晶体偏置电压从0V到3500V时,紫外激光二极管照射CdTe和BSO诱导的调制信号幅度从0%增加到2%(归一化到平均信号电平)。晶体偏置电压从0V到1500 V时,CdTe的调制信号幅值从0%增加到12%;晶体偏置电压从0V到3500 V时,BSO的调制信号幅值从0%增加到10%。因此,电子倍增效应(高晶体偏压)有望显著提高调制信号幅度,最终目标是实现单个511 keV光子检测。
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引用次数: 1
期刊
2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)
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