Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.015
Zakhar M. Rubanov, Mikhail D. Kosobokov, Vitalij V. Levin, Alexander D. Dilman
The alkylation of cyclic five-membered azomethine imines with carboxylic acids proceeds under irradiation with 400 nm light using a dual catalytic system consisting of 9-arylacridine and tetrabutylammonium decatungstate. Azomethine imines containing aromatic, heterocyclic and aliphatic groups are suitable for the process providing pyrazolidin-3-ones in 42–98% yields.
{"title":"Visible light-driven decarboxylative alkylation of azomethine imines with carboxylic acids","authors":"Zakhar M. Rubanov, Mikhail D. Kosobokov, Vitalij V. Levin, Alexander D. Dilman","doi":"10.1016/j.mencom.2024.09.015","DOIUrl":"10.1016/j.mencom.2024.09.015","url":null,"abstract":"<div><div>The alkylation of cyclic five-membered azomethine imines with carboxylic acids proceeds under irradiation with 400 nm light using a dual catalytic system consisting of 9-arylacridine and tetrabutylammonium decatungstate. Azomethine imines containing aromatic, heterocyclic and aliphatic groups are suitable for the process providing pyrazolidin-3-ones in 42–98% yields.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 673-675"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.021
Kseniya V. Belyaeva, Lina P. Nikitina, Ivan V. Saliy, Veronika S. Saliy, Andrei V. Afonin, Ludmila A. Oparina, Boris A. Trofimov
1-Methylisoquinoline undergoes stereoselective annulation with pyrrolylacetylenic ketones (MeCN, 80–82 °C) to provide (E)-acylethenylpyrrolo[1’,2’:3,4]imidazo[2,1-a]isoquinolines in up to 92% yield. In the case of 5-arylpyrrolylacetylenic ketones, instead of the above cyclization, the dimerization of the starting ketones to give dipyrrolopyrazines in 38 and 39% yields occurs.
{"title":"Annulation of 1-methylisoquinoline with pyrrolylacetylenic ketones: catalyst-free stereoselective synthesis of (E)-acylethenylpyrrolo[1’,2’:3,4]imidazo[2,1-a]isoquinolines","authors":"Kseniya V. Belyaeva, Lina P. Nikitina, Ivan V. Saliy, Veronika S. Saliy, Andrei V. Afonin, Ludmila A. Oparina, Boris A. Trofimov","doi":"10.1016/j.mencom.2024.09.021","DOIUrl":"10.1016/j.mencom.2024.09.021","url":null,"abstract":"<div><div>1-Methylisoquinoline undergoes stereoselective annulation with pyrrolylacetylenic ketones (MeCN, 80–82 °C) to provide (<em>E</em>)-acylethenylpyrrolo[1<em>’</em>,2<em>’</em>:3,4]imidazo[2,1-<em>a</em>]isoquinolines in up to 92% yield. In the case of 5-arylpyrrolylacetylenic ketones, instead of the above cyclization, the dimerization of the starting ketones to give dipyrrolopyrazines in 38 and 39% yields occurs.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 691-693"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.019
Yuliya S. Bortnevskaya , Viktoriya A. Malikova , Natalia Yu. Karpechenko , Natal’ya A. Bragina , Kseniya A. Zhdanova
New phototherapeutic agents based on synthetic porphyrin- type tetrapyrroles and small-molecule-targeted tyrosine kinase inhibitor Erlotinib have been synthesized based on the scheme involving ‘click’ reaction between bis(4- azidophenyl)-containing zinc porphyrinate derivative and N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)- quinazoline. The final compound and its precursors were tested as potential photosensitizers for targeted photo- dynamic therapy (PDT), the conjugate having shown photoinduced cytotoxicity IC50 for NKE cells 0.86 ± 0.017 μm and for A431 cells 0.54 ± 0.011 μm.
{"title":"The ‘click’ synthesis of new cytotoxic conjugate based on meso-arylporphyrin and Erlotinib","authors":"Yuliya S. Bortnevskaya , Viktoriya A. Malikova , Natalia Yu. Karpechenko , Natal’ya A. Bragina , Kseniya A. Zhdanova","doi":"10.1016/j.mencom.2024.09.019","DOIUrl":"10.1016/j.mencom.2024.09.019","url":null,"abstract":"<div><div>New phototherapeutic agents based on synthetic porphyrin- type tetrapyrroles and small-molecule-targeted tyrosine kinase inhibitor Erlotinib have been synthesized based on the scheme involving ‘click’ reaction between bis(4- azidophenyl)-containing zinc porphyrinate derivative and <em>N</em>-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)- quinazoline. The final compound and its precursors were tested as potential photosensitizers for targeted photo- dynamic therapy (PDT), the conjugate having shown photoinduced cytotoxicity IC<sub>50</sub> for NKE cells 0.86 ± 0.017 μm and for A431 cells 0.54 ± 0.011 μm.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 685-687"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.044
Emmanuel Busillo , Pavel A. Vlasov , Valery I. Savchenko , Vladimir N. Smirnov , Vladimir S. Arutyunov
The Gibbs free energies of the formation of several polyynes (C6H2, C10H2 and C16H2) and aromatic species (C6H6, C10H8 and C16H10) from methane and acetylene at temperatures of 1000–2600 K and atmospheric pressure were obtained by quantum chemical calculations using the RI-MP2 method in the ORCA open source software. At lower temperatures, aromatic species form more readily than polyynes, while at temperatures >2200 K the trend reverses and polyyne formation becomes predominant.
{"title":"Thermodynamics of the formation of polyynes and aromatic species from methane and acetylene","authors":"Emmanuel Busillo , Pavel A. Vlasov , Valery I. Savchenko , Vladimir N. Smirnov , Vladimir S. Arutyunov","doi":"10.1016/j.mencom.2024.09.044","DOIUrl":"10.1016/j.mencom.2024.09.044","url":null,"abstract":"<div><div>The Gibbs free energies of the formation of several polyynes (C<sub>6</sub>H<sub>2</sub>, C<sub>10</sub>H<sub>2</sub> and C<sub>16</sub>H<sub>2</sub>) and aromatic species (C<sub>6</sub>H<sub>6</sub>, C<sub>10</sub>H<sub>8</sub> and C<sub>16</sub>H<sub>10</sub>) from methane and acetylene at temperatures of 1000–2600 K and atmospheric pressure were obtained by quantum chemical calculations using the RI-MP2 method in the ORCA open source software. At lower temperatures, aromatic species form more readily than polyynes, while at temperatures >2200 K the trend reverses and polyyne formation becomes predominant.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 762-765"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.003
Yulia N. Toikka , Alexander R. Badikov , Nikita A. Bogachev , Ilya E. Kolesnikov , Mikhail Yu. Skripkin , Sergey N. Orlov , Andrey S. Mereshchenko
Two new heterometallic lutetium(III)–europium(III) terephthalate metal–organic frameworks were synthesized. The compounds demonstrated bright red emission of Eu3+ ions upon UV excitation into the 1ππ* excited state of terephthalate anion. Photoluminescence properties of the compounds were shown to be determined by the local environment of europium ions.
{"title":"Luminescent properties and thermal stability of (Lu0.98Eu0.02)2bdc3·10H2O metal–organic frameworks","authors":"Yulia N. Toikka , Alexander R. Badikov , Nikita A. Bogachev , Ilya E. Kolesnikov , Mikhail Yu. Skripkin , Sergey N. Orlov , Andrey S. Mereshchenko","doi":"10.1016/j.mencom.2024.09.003","DOIUrl":"10.1016/j.mencom.2024.09.003","url":null,"abstract":"<div><div>Two new heterometallic lutetium(III)–europium(III) terephthalate metal–organic frameworks were synthesized. The compounds demonstrated bright red emission of Eu<sup>3+</sup> ions upon UV excitation into the <sup>1</sup>ππ* excited state of terephthalate anion. Photoluminescence properties of the compounds were shown to be determined by the local environment of europium ions.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 634-636"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.004
Alexey A. Dovzhenko , Anna A. Betina , Tatyana S. Bulatova , Nikita A. Bogachev , Vladimir G. Nikiforov , Alexandra D. Voloshina , Rustem R. Zairov , Asya R. Mustafina , Andrey S. Mereshchenko , Bulat S. Akhmadeev
This work introduces non-covalent hydrophilic coating of NaGd0.7Eu0.3F4 nanocrystals by polylysine (PL) and polyethyleneimine (PEI) for MRI and fluorescent imaging purposes. PL- and PEI-stabilized nanocrystals exhibit high colloidal stability, cell internalization, fluorescent contrasting of nuclei and cytoplasm, low cytotoxicity, and relaxivity (r1= 0.17 dm3 mmol–1 s–1 and r1 = 0.23 dm3 mmol–1 s–1).
{"title":"Dual contrasting ability of NaGd0.7Eu0.3F4 nanocrystals tuned by their hydrophilic coating mode","authors":"Alexey A. Dovzhenko , Anna A. Betina , Tatyana S. Bulatova , Nikita A. Bogachev , Vladimir G. Nikiforov , Alexandra D. Voloshina , Rustem R. Zairov , Asya R. Mustafina , Andrey S. Mereshchenko , Bulat S. Akhmadeev","doi":"10.1016/j.mencom.2024.09.004","DOIUrl":"10.1016/j.mencom.2024.09.004","url":null,"abstract":"<div><div>This work introduces non-covalent hydrophilic coating of NaGd<sub>0.7</sub>Eu<sub>0.3</sub>F<sub>4</sub> nanocrystals by polylysine (PL) and polyethyleneimine (PEI) for MRI and fluorescent imaging purposes. PL- and PEI-stabilized nanocrystals exhibit high colloidal stability, cell internalization, fluorescent contrasting of nuclei and cytoplasm, low cytotoxicity, and relaxivity (<em>r</em><sub>1</sub>= 0.17 dm<sup>3</sup> mmol<sup>–1</sup> s<sup>–1</sup> and <em>r</em><sub>1</sub> = 0.23 dm<sup>3</sup> mmol<sup>–1</sup> s<sup>–1</sup>).</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 637-639"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.001
Anton A. Yakimanskiy, Alexander M. Mitroshin, Tatiana G. Chulkova, Sergey A. Miltsov, Alexander V. Yakimansky
Copolyfluorenes have drawn considerable attention owing to their remarkable optoelectronic characteristics, chemical and thermal stability, good film-forming properties, and thus present an active subject of cutting-edge research in the organic electroluminescence. This current systematic review examines and summarizes the latest research on copolyfluorene-based materials for light emitting layers of OLEDs over the past decades.
{"title":"Fluorene-based π-conjugated polymers for OLEDs: advances, opportunities, and challenges","authors":"Anton A. Yakimanskiy, Alexander M. Mitroshin, Tatiana G. Chulkova, Sergey A. Miltsov, Alexander V. Yakimansky","doi":"10.1016/j.mencom.2024.09.001","DOIUrl":"10.1016/j.mencom.2024.09.001","url":null,"abstract":"<div><div>Copolyfluorenes have drawn considerable attention owing to their remarkable optoelectronic characteristics, chemical and thermal stability, good film-forming properties, and thus present an active subject of cutting-edge research in the organic electroluminescence. This current systematic review examines and summarizes the latest research on copolyfluorene-based materials for light emitting layers of OLEDs over the past decades.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 609-629"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.039
Boris A. Gostevsky, Alexander V. Vashchenko, Nataliya F. Lazareva
The single-crystal X-ray study of ClSi(OCH2CH2)3N showed the formation of a cluster of three silatrane molecules with one acetonitrile molecule featuring hypercoordinated Si atoms in a trigonal-bipyramidal coordination environment with O atom in the equatorial plane. A number of solid-phase structural parameters and the conformation of the fivemembered rings of 1-chlorosilatrane were thus clarified.
ClSi(OCH2CH2)3N 的单晶 X 射线研究表明，由三个硅烷分子与一个乙腈分子组成的硅烷簇具有超配位硅原子，处于三叉双锥配位环境中，O 原子位于赤道面上。因此，1-氯硅烷的一些固相结构参数和五元环的构象得到了澄清。
{"title":"X-ray structural study of 3:1 solvate of 1-chlorosilatrane with MeCN","authors":"Boris A. Gostevsky, Alexander V. Vashchenko, Nataliya F. Lazareva","doi":"10.1016/j.mencom.2024.09.039","DOIUrl":"10.1016/j.mencom.2024.09.039","url":null,"abstract":"<div><div>The single-crystal X-ray study of ClSi(OCH<sub>2</sub>CH<sub>2</sub>)<sub>3</sub>N showed the formation of a cluster of three silatrane molecules with one acetonitrile molecule featuring hypercoordinated Si atoms in a trigonal-bipyramidal coordination environment with O atom in the equatorial plane. A number of solid-phase structural parameters and the conformation of the fivemembered rings of 1-chlorosilatrane were thus clarified.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 745-747"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.042
Nazgul S. Murzakasymova , Nesipkhan A. Bektenov , Kiril V. Serebriakov , Egor S. Yelkin , Mikhail A. Gavrilenko
The citric acid modification produces an intermediate layer on the AB-17-8:C6H8O7 surface; the layer, on one hand, is firmly secured to the surface owing to the electrostatic coupling between the citrate anion and the positively charged trimethylammonium centers of the anion exchanger surface; on the other hand, it has carbonyl groups with a local negative electron density. The sorption of heavy metals cations occurs through coordination interactions via electrostatic mechanism with local centers of negative electron density, in particular, with the carbonylic oxygen atom.
{"title":"Control for selective sorption of heavy metals cations with anion exchanger AB-17-8 by modifying the surface with citrate groups","authors":"Nazgul S. Murzakasymova , Nesipkhan A. Bektenov , Kiril V. Serebriakov , Egor S. Yelkin , Mikhail A. Gavrilenko","doi":"10.1016/j.mencom.2024.09.042","DOIUrl":"10.1016/j.mencom.2024.09.042","url":null,"abstract":"<div><div>The citric acid modification produces an intermediate layer on the AB-17-8:C<sub>6</sub>H<sub>8</sub>O<sub>7</sub> surface; the layer, on one hand, is firmly secured to the surface owing to the electrostatic coupling between the citrate anion and the positively charged trimethylammonium centers of the anion exchanger surface; on the other hand, it has carbonyl groups with a local negative electron density. The sorption of heavy metals cations occurs through coordination interactions <em>via</em> electrostatic mechanism with local centers of negative electron density, in particular, with the carbonylic oxygen atom.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 755-757"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.mencom.2024.09.030
Igor S. Mashkovsky , Nadezhda S. Smirnova , Pavel V. Markov , Galina N. Baeva , Anastasia E. Vaulina , Dmitry P. Melnikova , Alexander Yu. Stakheev
A herein proposed PdAu/Al2O3 egg-shell catalyst for selective acetylene hydrogenation combines two factors to provide perfect performance: isolation of Pd1 active sites by Au and an egg-shell distribution of the active phase across the catalyst pellets. The PdAu/Al2O3 catalyst exhibits high acetylene hydrogenation activity at the level of Pd-catalysts and high intrinsic ethylene selectivity of Au-catalysts.
本文提出的一种用于选择性乙炔加氢的 PdAu/Al2O3 蛋壳催化剂结合了两个因素以提供完美的性能：用金隔离 Pd1 活性位点以及活性相在催化剂颗粒上的蛋壳分布。PdAu/Al2O3 催化剂在 Pd 催化剂的水平上表现出较高的乙炔氢化活性，在 Au 催化剂的水平上表现出较高的内在乙烯选择性。
{"title":"Performance of PdAu/Al2O3 egg-shell catalyst with isolated Pd1 sites for selective hydrogenation of acetylene","authors":"Igor S. Mashkovsky , Nadezhda S. Smirnova , Pavel V. Markov , Galina N. Baeva , Anastasia E. Vaulina , Dmitry P. Melnikova , Alexander Yu. Stakheev","doi":"10.1016/j.mencom.2024.09.030","DOIUrl":"10.1016/j.mencom.2024.09.030","url":null,"abstract":"<div><div>A herein proposed PdAu/Al<sub>2</sub>O<sub>3</sub> egg-shell catalyst for selective acetylene hydrogenation combines two factors to provide perfect performance: isolation of Pd<sub>1</sub> active sites by Au and an egg-shell distribution of the active phase across the catalyst pellets. The PdAu/Al<sub>2</sub>O<sub>3</sub> catalyst exhibits high acetylene hydrogenation activity at the level of Pd-catalysts and high intrinsic ethylene selectivity of Au-catalysts.</div></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 5","pages":"Pages 718-720"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号