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Periprosthetic fractures of total hip arthroplasty: a review of literature with a point of view 全髋关节置换术后假体周围骨折的文献综述
Pub Date : 2022-10-08 DOI: 10.33140/mcr.07.10.07
S. Bernardino
Periprosthetic fractures associated with total hip arthroplasty are becoming increasingly more common. The purpose of study is to review the treatment of periprosthetic fractures of total hip arthroplasty. A limitated number of cases is proposed. Careful intraoperative technique and tissue handling are crucial to reduce periprosthetic fractures. Once identified, however, any number of well described the treatment options are available for the surgeons. Carefully approached, and using sound treatment principles, these fractures can be appropriately addressed, thus ensuring adequate patient results. In this review, there are not outcome and tables.
与全髋关节置换术相关的假体周围骨折越来越常见。本研究旨在回顾全髋关节置换术后假体周围骨折的治疗方法。提出的案例数量有限。谨慎的术中技术和组织处理是减少假体周围骨折的关键。然而,一旦确定,外科医生可以选择许多描述良好的治疗方案。谨慎处理,采用合理的治疗原则,这些骨折可以得到适当的处理,从而确保患者得到充分的治疗效果。在本综述中,没有结果和表格。
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引用次数: 0
Seeds, kernels, germs, sprouts and their oils as potent remedies 种子,果仁,细菌,芽和它们的油是有效的补救措施
Pub Date : 2022-10-08 DOI: 10.33140/mcr.07.10.09
Seeds, kernels, sprouts and their oils are potent healing agents. They are insufficiently appreciated and used in the context of common medicine. However, since they are inexpensive and have almost no side effects, they should be used more frequently. Acquiring them is possible for everyone who strives for a health-conscious lifestyle. Since today, as a result of the multitude of negative environmental effects, it is almost impossible to stay healthy without upgrading one’s diet and using dietary supplements, this should be widely propagated.
种子,果仁,芽和它们的油是有效的愈合剂。在普通医学的背景下,它们没有得到充分的重视和使用。然而,由于它们便宜,几乎没有副作用,它们应该更频繁地使用。每个追求注重健康的生活方式的人都有可能获得它们。因为今天,由于众多的负面环境影响,如果不改善饮食和使用膳食补充剂,几乎不可能保持健康,这应该得到广泛宣传。
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引用次数: 0
Mechanisms of myofascial pain in the context of metabolism, redox stress and inflammation: a narrative review 代谢、氧化还原应激和炎症背景下肌筋膜疼痛的机制:叙述性回顾
Pub Date : 2022-10-05 DOI: 10.33140/mcr.07.10.04
Pain syndromes usually progress spatially in a stepwise fashion. Myofascial trigger points, a best-studied feature of myofascial pain syndrome and a very common finding on clinical examination of people with various chronic pain syndromes, occur in an active or latent form, consistent with the clinical features of myofascial pain syndrome, and progress from a less painful state to a more painful one. The clinical presentation apparently encompasses a continuum from barely detectable clinical phenomena of latent trigger points to a complex chronic pain syndrome with currently unsatisfactory treatment options. The mechanisms of trigger point development, transition, and maintenance are not well understood. This review discusses the existing mechanistic evidence and proposes a new conceptualization based on disruption of growth/repair/energy utilisation in the neuromuscular system as one of the possible mechanistic backgrounds of the MPS phenomenon. Accordingly, research opportunities that should be explored in the future are discussed.
疼痛综合征通常在空间上以逐步的方式进展。肌筋膜触发点是肌筋膜疼痛综合征研究最充分的特征,也是各种慢性疼痛综合征患者临床检查中非常常见的发现。肌筋膜触发点以活动或潜伏形式出现,与肌筋膜疼痛综合征的临床特征一致,并从疼痛程度较轻的状态向疼痛程度较高的状态发展。临床表现显然包括一个连续体,从几乎无法检测到潜在触发点的临床现象到复杂的慢性疼痛综合征,目前治疗方案不满意。触发点的发展、转变和维持机制尚不清楚。本文讨论了现有的机制证据,并提出了一个基于神经肌肉系统生长/修复/能量利用中断的新概念,作为MPS现象的可能机制背景之一。在此基础上,讨论了今后应探索的研究机会。
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引用次数: 0
Correlation of vitamin D with osteoporosis 维生素D与骨质疏松症的相关性
Pub Date : 2022-10-05 DOI: 10.33140/mcr.07.10.01
Sander Kola, I. Kola, Kristina Gjoka, AnxhelaGjini
Introduction: Osteoporosis is a disease of bone metabolism, which is characterized by the silent and progressive reduction of bone density and is followed by a risk for fractures that can be fatal to the patient. The causes leading to this disease are endogenous and exogenous, but it is mainly related to the decrease in vitamin D level. Aim: Our study is the review and presentation of a more complete picture regarding osteoporosis and the effect of vitamin D on osteoporosis. Material and Method: Is a literary review of studies published in PubMed, Medline, WebMD, on the topic of vitamin D and its correlation with osteoporosis, an essential indicator with a wide range of applications in diagnosis and analysis of this illness. The scientific studies referenced, highlight the effectiveness of diagnosing osteoporosis through a bone density scan with a dual energy X-ray (DEXA), which provides the most accurate assessment to date on bone density. According to ‘International Osteoporosis Foundation’ statistics conducted for EU countries, Switzerland, UK the estimated number of individuals with osteoporosis above 50 years old in 2019 was 32 million, from which 25.5 million were of the gender female and 6.5 millionmale, deriving the conclusion that females are more prone to osteoporosis. Apart from diagnosis of osteoporosis,in the studies referenced,of great importance is the role of vitamin D levels and its correspondence with osteoporosis. In a study by Michael Holick Vitamin D deficiency. N Engl J Med. a vitamin D deficiency is defined by concentration of 25(OH)D less than 10ng/mL and an insufficiency of 20-30 ng/mL. At last, treatments and recommendations for osteoporosis regarding vitamin D deficiency have elaborated to supplementary diets, bisphosphonates treatments and even hormone replacement therapy. Conclusion: 25-OH-Vitamin D is essential for vitamin D status. To prevent the rapid progress of osteoporosis, factors that need immediate attention such as diet, lifestyle and an early diagnosis through DEXA are to be a priority, especially in risk patients.
骨质疏松症是一种骨代谢疾病,其特点是骨密度无声和进行性降低,随后有骨折的危险,对患者来说可能是致命的。导致本病的原因有内源性和外源性,但主要与维生素D水平下降有关。目的:我们的研究是对骨质疏松症和维生素D对骨质疏松症的影响进行更全面的回顾和介绍。材料与方法:是对发表在PubMed, Medline, WebMD上的关于维生素D及其与骨质疏松症相关性的研究的文献综述,维生素D是骨质疏松症诊断和分析中广泛应用的重要指标。引用的科学研究强调了通过双能x射线(DEXA)骨密度扫描诊断骨质疏松症的有效性,它提供了迄今为止最准确的骨密度评估。根据“国际骨质疏松基金会”对欧盟国家、瑞士、英国进行的统计,2019年50岁以上骨质疏松症患者的估计人数为3200万,其中女性2550万,男性650万,由此得出女性更容易患骨质疏松症的结论。除了骨质疏松症的诊断外,在所引用的研究中,维生素D水平的作用及其与骨质疏松症的对应关系非常重要。在Michael Holick的一项研究中维生素D缺乏症。维生素D缺乏的定义是25(OH)D浓度低于10ng/mL和不足20- 30ng /mL。最后,关于维生素D缺乏的骨质疏松症的治疗和建议已经细化到补充饮食、双膦酸盐治疗甚至激素替代疗法。结论:25- oh -维生素D是维持维生素D状态所必需的。为了防止骨质疏松症的快速发展,需要立即注意的因素,如饮食、生活方式和通过DEXA进行早期诊断,是优先考虑的,特别是在高危患者中。
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引用次数: 0
Diagnosis and treatment of frozen shoulder with shock-wave therapy 冲击波治疗肩周炎的诊断与治疗
Pub Date : 2022-10-05 DOI: 10.33140/mcr.07.10.02
I. Kola, Sander Kola, D. Mata, Esmeralda Novruzaj, Rea Sherifi
Introduction: Adhesive capsulitis is pathology of the gleno-humeral joint that causes joint pain and immobility. The cause in most cases is unknown. Conservative treatment is good but still unclear, ESWT is an adjunctive and effective therapy for treatment. Objectives: To analyze the effectiveness of Shock-Wave therapy (ESWT) in the treatment of pain and ROM in frozen shoulder. Method: We based on 7 studies, taken from medical websites (PubMed,Medline, WebMD, MedScope). Patients diagnosed with adhesive capsulitis in all studies taken in reference were randomly divided into two groups. In studies [1], Extracorporeal shockwave therapy improves short-term functional outcomes of shoulder adhesive capsulitis and [3], Extracorporeal Shockwave Therapy Improves Functional Outcomes of Adhesive Capsulitis of the Shoulder in Patients With Diabetes one group was treated with ESWT, the other with oral AINS In studies [2]. The efficacy of radial extracorporeal shockwave therapy in shoulder adhesive capsulitis: a prospective, randomised, double-blind, placebo-controlled, clinical study one group was treated with ESWT, and the other with placebo treatment. In study [4], the effects of extracorporeal shock wave therapy on frozen shoulder patients’ pain and functions. All patients received NSAIDs once a day. The subjects of this study were divided into the conservative physical therapy group one group was treated with ESWT, All subjects were treated 2 times a week for 6 weeks. In within-group comparisons of VAS and PSFS, both ESWT and CPT groups showed significant decreases in VAS and PSFS. In comparisons between VAS and PSFS groups, ESWTG showed much lower results compared to CPTG. In studies [6], Efficacy of Extracorporeal Shockwave Therapy in Frozen Shoulder and [7] Shock Wave Therapy and Ultrasound Therapy plus Exercises for Frozen Shoulder Joint Clients, one group was treated with ESWT, the other with conservative physical therapy Results: For the studies considered it was observed that: patients treated with ESWT have an earlier and more noticeable improvement in pain and functionality, articular ROM compared to the effect from other treatments such as: (placebo, AINS, conservative treatment, ultrasound) applied to patients. Conclusions: Based on the above studies, it is concluded that ESWT is more effective in treating pain and functionality, articular ROM, compared to other treatments applied to the groups of patients diagnosed with adhesive capsulitis.
简介:粘连性肩关节囊炎是一种引起关节疼痛和不活动的关节病变。在大多数情况下,原因是未知的。保守治疗效果良好但尚不明确,ESWT是一种辅助有效的治疗方法。目的:分析冲击波疗法(ESWT)治疗肩周炎和疼痛的疗效。方法:我们基于从医学网站(PubMed,Medline, WebMD, MedScope)上获取的7项研究。所有参考研究中诊断为粘连性囊炎的患者随机分为两组。在研究[1]中,体外冲击波治疗改善肩关节粘连性囊炎的短期功能结局[3],体外冲击波治疗改善糖尿病肩关节粘连性囊炎的功能结局研究[2]中,一组采用ESWT治疗,另一组采用口服AINS治疗。桡骨体外冲击波治疗肩关节粘连性囊炎的疗效:一项前瞻性、随机、双盲、安慰剂对照的临床研究,一组采用ESWT治疗,另一组采用安慰剂治疗。在研究[4]中,体外冲击波治疗对肩周炎患者疼痛和功能的影响。所有患者每天接受一次非甾体抗炎药治疗。本研究将受试者分为保守物理治疗组,其中一组采用ESWT治疗,所有受试者每周治疗2次,持续6周。在VAS和PSFS的组内比较中,ESWT组和CPT组的VAS和PSFS均显著降低。在VAS组和PSFS组的比较中,ESWTG的结果比CPTG低得多。在研究[6]《体外冲击波治疗肩周炎的疗效》和研究[7]《冲击波治疗和超声治疗加运动治疗肩周炎患者》中,一组采用ESWT治疗,另一组采用保守的物理治疗。结果:研究发现:与其他治疗相比,采用ESWT治疗的患者在疼痛和功能、关节ROM方面的改善更早、更明显,如:(安慰剂、AINS、保守治疗、超声)应用于患者。结论:综合以上研究,ESWT在治疗粘连性囊炎患者组的疼痛和功能、关节ROM方面比其他治疗方法更有效。
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引用次数: 0
Clinical characteristics of patients with lyme arthritis diagnosed in children from Ternopil region 捷尔诺波尔地区儿童莱姆病的临床特征分析
Pub Date : 2022-10-05 DOI: 10.33140/mcr.07.10.05
Objectives: The article deals with clinical picture of Lyme arthritis (LA) and clinical features distinguishing this form of arthritis from other forms. The description of the characteristic features of arthritis based on laboratory and instrumental examinations of children was presented in the article. The clinical manifestation of LA is very changeable what makes diagnosis difficult to define. The aim of our study was to prove that LA should be treated with antibiotic therapy. Material and Methods: The authors present two cases of arthritis in children on the background of the tick bite, and systemic juvenile idiopathic arthritis (SJIA). Lyme arthritis (LA) was found in 7.0% of 200 examined children. Сase study presentation as a basis for discussion, a literature search of MEDLINE and Scopus database. A review of the examination of biomarkers among patients with LA and Rheumatoid arthritis according to MEDLINE via OVID, EMBASE, and Web of Science databases was conducted systematically and 21 examinations were taken for qualitative analysis. Results: Clinical characteristics was defined by an increase in body temperature, persistent monoarthritis and synovitis. Serological studies (Elisa and Immunoblot assays) were predominant factors for establishment the diagnosis even in case of the absence of epidemiological history. Conclusions: 1. The investigation proved that LA is manifested by increasing body temperature, persistent mono arthritis, and synovitis. 2. There were presented that serological studies (Elisa and Immunoblot) are determining factors for diagnosis verification even in case of the absence of epidemiological history. 3. It was proved that genetic examination on HLA antigen B27 is necessary for differential diagnosis of arthritis. 4. The given investigation based on laboratory and instrumental examinations of children showed that Lyme arthritis treatment envisages antibiotic therapy and rheumatoid arthritis and requires non-steroid plus antibiotic therapy
目的:探讨莱姆病(LA)的临床表现及区别于其他关节炎的临床特点。本文介绍了基于儿童实验室和仪器检查的关节炎特征的描述。LA的临床表现多变,诊断困难。我们研究的目的是证明LA应该用抗生素治疗。材料和方法:作者报告两例儿童关节炎的背景蜱叮咬,和系统性青少年特发性关节炎(SJIA)。200名接受检查的儿童中有7.0%发现莱姆病。Сase研究报告作为讨论基础,文献检索MEDLINE和Scopus数据库。根据MEDLINE通过OVID、EMBASE和Web of Science数据库对LA和类风湿关节炎患者的生物标志物检查进行系统回顾,并采取21项检查进行定性分析。结果:临床特征为体温升高,持续性单关节炎和滑膜炎。即使在没有流行病学史的情况下,血清学研究(Elisa和免疫印迹测定)也是确定诊断的主要因素。结论:1。调查证实LA表现为体温升高、持续性单关节关节炎和滑膜炎。2. 有人提出,即使在没有流行病学史的情况下,血清学研究(Elisa和免疫印迹)也是诊断验证的决定性因素。3.证实HLA抗原B27的遗传检查是鉴别诊断关节炎的必要条件。4. 基于实验室和仪器检查的儿童调查显示,莱姆病治疗设想抗生素治疗和类风湿关节炎,需要非类固醇加抗生素治疗
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引用次数: 0
Increased incidence of unexpected death due to spike proteins- case report 刺突蛋白引起的意外死亡发生率增加-病例报告
Pub Date : 2022-10-05 DOI: 10.33140/mcr.07.10.06
Patient P.S. (male, born 1948) presented in April 2022 with a diagnosis of right lung carcinoma with multiple metastases to the brain. The biopsy had revealed a non-small cell lung carcinoma. He refused a usual chemotherapy because he had read on the Internet that the probability of cure with this diagnosis was only 1-2%. This was certainly right.
患者P.S.(男,1948年出生)于2022年4月被诊断为右肺癌并多发性脑转移。活检显示为非小细胞肺癌。他拒绝了常规的化疗,因为他在网上看到这种诊断的治愈概率只有1-2%。这当然是对的。
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引用次数: 0
Arthroscopic needle knife for knee video arthroscopic surgical portals 膝关节视频关节镜手术门静脉的关节镜针刀
Pub Date : 2022-10-01 DOI: 10.33140/mcr.07.09.03
F.F.D.A. Ravaglia, A. C. Junior
Introduction: A new era of orthopedic surgery is happening nowadays. innovative procedures like video surgery; Ultrasound Guided Interventions; Pain interventionist orthopedics procedures; plastic surgery (cellulites subcision treatment); hydrodissection injections; dry needling; thermography assisted pain procedures and acupuncture started to be widely performed [3]. Objective: The aim of the research is to assess the possibility of a needle knife surgical device to perform portals of knee video arthroscopic surgical interventions and to evaluate the two diferentes needle-knife surgical devices [7-9]. Method: 200 consecutive knee Video Arthroscopies performed by the same team were divided in two groups: A and B. Group A: the lateral portal used a hypodermic needle 40X12 (18Gx 1’1/2) for portal performance. Group B submitted a lateral portal using a metal guide for intravenous catheter 14Gx2’’. The medial portal, a 11 blade knife, was used for both cases.Comparison of two groups by assessing wound healing time; superficial and deep infection; pain, cosmesis by a third person nurse.A surgeon’s opinion for friendly use comparing group A or B was made [8, 9]. Results: There were nor superficial or deep knee infections. No wound healing problems, same time of healing. No difference in pain related to the wound. Cosmesis were similar. The surgeon’s choice was the metal guide for intravenous catheter 14Gx2’’ is more friendly due to the rigidity in comparison to a hypodermic needle 40X12 (18Gx 1’1/2). Conclusion: The two needles seem suitable for knee video arthroscopy surgical interventions. The surgeon’s choice was the metal guide for intravenous catheter 14Gx2’’ is more friendly due to the rigidity in comparison to the 40x12 needle [7-9].
导读:骨科手术的新时代正在到来。视频手术等创新程序;超声引导干预;疼痛介入骨科手术;整形手术(脂肪团瘦身治疗);注射囊袋上;干针刺;热成像辅助疼痛治疗和针灸开始广泛应用[3]。目的:本研究的目的是评估针刀手术装置进行膝关节视频关节镜手术干预的可能性,并评估两种不同的针刀手术装置[7-9]。方法:同一组连续行200例膝关节视频关节镜检查,分为A组和b组。A组:门静脉外侧使用40X12 (18Gx 1’1/2)皮下穿刺针检查门静脉表现。B组采用金属导管14Gx2”行侧门静脉。两个病例均使用了内侧门静脉,一把11刃刀。两组比较伤口愈合时间;浅表和深部感染;疼痛,由第三者护士化妆。比较A组和B组,提出术者的友好使用意见[8,9]。结果:无浅、深膝关节感染。没有伤口愈合问题,愈合时间相同。与伤口相关的疼痛没有区别。化妆品也是类似的。外科医生选择了14Gx2”的金属导管,与40X12 (18Gx 1 ' 1/2)的皮下针头相比,它的硬度更友好。结论:双针适合于膝关节视频关节镜手术干预。外科医生选择了14Gx2”的金属导管,与40x12针头相比,金属导管的刚性更强[7-9]。
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引用次数: 0
Forgotten intrauterine device inducing aseptic peritonitis in newly started peritoneal dialysis 遗忘宫内节育器诱导新开始腹膜透析的无菌性腹膜炎
Pub Date : 2022-10-01 DOI: 10.33140/mcr.07.09.01
Infectious peritonitis is a challenging condition to continuing peritoneal dialysis (PD) in many end-stage renal disease patients. A cloudy peritoneal effluent or abdominal pain is the most common symptoms of peritonitis, which would be confirmed with peritoneal leukocytosis. However, not all cloudy effluent and peritoneal leukocytosis are infectious in etiology. Here, we report a case of peritoneal leukocytosis related to a forgotten intrauterine device (IUD), where antibiotic therapy failed to achieve a clinical change. This case report and literature review provides insight into a rare but significant presentation of aseptic peritonitis and highlights the need to consider IUD interaction with PD dialysate as a reason for aseptic peritonitis.
感染性腹膜炎是许多终末期肾脏疾病患者继续腹膜透析(PD)的一个挑战。腹膜流出物混浊或腹痛是腹膜炎最常见的症状,可由腹膜白细胞增多症证实。然而,并非所有的排出物混浊和腹膜白细胞增多在病因上都是传染性的。在这里,我们报告一例腹膜白细胞增多症与遗忘宫内节育器(IUD)有关,抗生素治疗未能实现临床改变。本病例报告和文献回顾提供了一种罕见但重要的无菌性腹膜炎的表现,并强调需要考虑宫内节育器与PD透析液的相互作用是无菌性腹膜炎的原因。
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引用次数: 0
Persistent neuropathic pain treated with capsaicin patches: a novel promising approach 辣椒素贴片治疗持续性神经性疼痛:一种有希望的新方法
Pub Date : 2022-10-01 DOI: 10.33140/mcr.07.09.02
G. Gagliardi, Veronica Gagliardi, Angelo Butturini, G. Ferraro, F. Ceccherelli
Neuropathic pain is associated with a functional abnormality of the nervous system due to a direct lesion or disease of the somatosensory system, leading to a continuous pattern of pointless and detrimental pain signal: the pain itself rather than the predisposing condition becomes the main pathological element. In this framework, capsaicin has been used in several clinical settings as a topical medication to treat neuropathic pain. We report three cases of persistent neuropathic pain who underwent our protocol: three applications of the capsaicin 8% patch separated by one month. In all the reported cases, the outcome has been a significant reduction of the symptoms, and the pain relief has maintained, staggered only by sporadic episodes of exacerbation. The treatment is safe and effective in reducing the intensity of the pain, being a valid therapy for the treatment of the chronic neuropathic pain, administered in association with other drugs.
神经性疼痛与躯体感觉系统的直接损伤或疾病引起的神经系统功能异常有关,导致无意义和有害的疼痛信号的持续模式:疼痛本身而不是易感条件成为主要的病理因素。在这个框架下,辣椒素已经在一些临床设置作为局部药物治疗神经性疼痛。我们报告了三例持续性神经性疼痛患者,他们接受了我们的治疗方案:三次使用8%辣椒素贴片,间隔一个月。在所有报告的病例中,结果都是症状显著减轻,疼痛持续缓解,只是偶尔发作加剧。该疗法安全有效地减轻了疼痛的强度,是治疗慢性神经性疼痛的有效疗法,与其他药物联合使用。
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引用次数: 0
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Medical & Clinical Research
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