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An in-vivo study on the effect of head orientation in the measurement of anthropometric points in stereophotogrammetry. 立体摄影测量中头部方向对人体测量点测量影响的活体研究。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-06 DOI: 10.23736/S2724-6329.24.04852-6
Marco DI Blasio, Giuseppe Minervini, Marzia Segù, Giuseppe Pedrazzi, Alberto DI Blasio, Diana Cassi, Marco Cicciù, Bendetta Vaienti

Background: It is well known that in bidimensional photography the orientation of the head is fundamental to obtain a correct reproduction of the subject. Even minimal errors in yaw, roll and pitch of the head can be cause of unreliability of the photography itself. This is not the case in three-dimensional photography in which head positioning may have no influence on the reliability of the results since on the computer the 3D reconstruction of the face can be oriented as desired, allowing any small errors to be corrected. The authors, in a previous in-vitro study, demonstrated this using a mannequin of the head. In the present study, the Authors repeat the study in vivo to verify any differences.

Methods: Seventeen anthropometric points were marked on the face of a young adult female (26 years old) with eyeliner. Images of the face were then acquired with a stereo-photogrammetric system (Face Shape 3D MaxiLine) in natural head position and with varying degrees of roll, pitch and yaw. The anthropometric points marked on the skin were then recognized and marked on a digital software (Viewbox, dHAL Software, 6 Menandrou Street, Kifissia 14561, Greece) on each individual image. 14 linear distances between these points were measured using the same software.

Results: The linear distances of these points in the stereophotos taken at centered positions were then compared with those taken with different degrees of roll, pitch and yaw. This study confirms previous results obtained in vitro regarding the presence of areas of non-equivalence (P<0.05) when comparing the frontal and lateral regions of the face at various angles.

Conclusions: However, it introduces important suggestions on the collection of data from specific anthropometric points. If these points are to be assessed, the medical staff will have to take special precautions to obtain reliable images.

背景:众所周知,在二维摄影中,头部的方向是正确再现拍摄对象的基础。即使头部在偏航、滚动和俯仰方面的误差很小,也会导致摄影本身不可靠。而三维摄影则不同,在三维摄影中,头部定位可能不会影响拍摄结果的可靠性,因为在计算机上,面部的三维重建可以按照需要调整方向,任何微小的误差都可以得到纠正。在之前的体外研究中,作者使用头部人体模型证明了这一点。在本研究中,作者重复了体内研究,以验证任何差异:方法:用眼线笔在一名年轻成年女性(26 岁)的面部标出 17 个人体测量点。然后用立体摄影测量系统(Face Shape 3D MaxiLine)在自然头位和不同程度的滚动、俯仰和偏航下采集面部图像。然后用数字软件(Viewbox, dHAL Software, 6 Menandrou Street, Kifissia 14561, Greece)在每张图像上识别并标记皮肤上的人体测量点。使用同一软件测量了这些点之间的 14 个线性距离:然后,将这些点在居中位置拍摄的立体照片中的线性距离与不同滚动、俯仰和偏航度拍摄的立体照片进行比较。这项研究证实了之前在体外获得的关于存在非等效区域(PConclusions)的结果:不过,该研究也对从特定人体测量点收集数据提出了重要建议。如果要对这些点进行评估,医务人员必须采取特别的预防措施,以获得可靠的图像。
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引用次数: 0
Craniofacial morphology in patients with impacted canine: a case control-study. 犬齿撞击患者的颅面形态:病例对照研究。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-04 DOI: 10.23736/S2724-6329.24.04979-9
Domenico Ciavarella, Mauro Lorusso, Martina Leone, Donatella Ferrara, Carlotta Fanelli, Gaetano Illuzzi, Eleonora Ortu, Lorenzo Lo Muzio, Michele Tepedino

Background: The objective of this study was to evaluate the risk of maxillary canine impaction through cephalometric evaluation.

Methods: One hundred and eighty-two Caucasian patients (80 males and 102 females) with a mean age of 12.4±0.5 were retrospectively enrolled in the present study. Ninety patients with impacted canines were compared with ninety-two patients with physiologically erupted canines. The following cephalometric variables were analyzed: SNA, ANB, SN-GOME, GO-ME, SP-CL, SELLA TURCICA DEPHT, A-Pt LINE, B-Pt LINE, A-Pt LINE°, B-Pt LINE°, A1s-Pt, A1i-Pt, A1s-Pt°, A1i-PT°, A-SN, B-SN and SN-U1. When applicable, a paired sample t-test was performed to investigate the difference in means between the two sample groups, while the Mann-Whitney Test was used as a non-parametric test in the case of a non-normal distribution of data. Statistical significance was set at P<0.05.

Results: The group with impacted canines showed an increase in Go-Me distance, SNA angle and A1s-Pt angle compared with the control group. In addition, the same group showed a decrease in A-SN and SP-Cl distance compared with the control group.

Conclusions: An increase in mandibular length (GO-ME) and SNA angle associated with a reduction in A-Sn distance and interclinoid distance (SP-Cl) were observed in patients with impacted canines.

背景: 本研究的目的是通过头颅测量评估上颌犬齿嵌塞的风险:本研究的目的是通过头颅测量评估上颌犬牙嵌塞的风险:本研究回顾性地纳入了 182 名白种人患者(男性 80 名,女性 102 名),他们的平均年龄为(12.4±0.5)岁。其中,92 名患者患有撞击性犬齿,92 名患者患有生理性萌出的犬齿。分析了以下头颅测量变量:SNA、ANB、SN-GOME、GO-ME、SP-CL、SELLA TURCICA DEPHT、A-Pt LINE、B-Pt LINE、A-Pt LINE°、B-Pt LINE°、A1s-Pt、A1i-Pt、A1s-Pt°、A1i-PT°、A-SN、B-SN 和 SN-U1。在适用的情况下,采用配对样本 t 检验来研究两个样本组之间的均值差异,而在数据非正态分布的情况下,则采用 Mann-Whitney 检验作为非参数检验。统计显著性设定为 PResults:与对照组相比,犬齿撞击组的 Go-Me 距离、SNA 角度和 A1s-Pt 角度均有所增加。此外,与对照组相比,该组的 A-SN 和 SP-Cl 距离也有所减少:结论:在犬齿撞击患者中观察到下颌长度(GO-ME)和SNA角度增加,而A-Sn距离和clinoid间距(SP-Cl)减少。
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引用次数: 0
The literature discusses oral manifestations caused by sexually transmitted viruses: a narrative review. 关于性传播病毒引起的口腔表现的文献综述。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-13 DOI: 10.23736/S2724-6329.24.04996-9
Alessandro Motta, Gennaro Musella, Tommaso Dai Prà, Andrea Ballini, Mario Dioguardi, Maria E Bizzoca, Lorenzo Lo Muzio, Stefania Cantore

This review provides practical recommendations for dental practitioners in dealing with oral lesions associated with sexually transmitted diseases (STDs), offering clinically relevant insights to increase the awareness of these diseases in the mainstream of everyday practice. STDs are acquired through unprotected vaginal, anal or oral sex and are caused by more than 30 different types of bacteria, viruses and protozoa. Saliva, precum, semen, vaginal secretions and menstrual blood could be likely vehicles of infections and defensive barriers to infection by pathogenic microbes could be represented via intact mucosal membrane, the diluent function of saliva, and the antimicrobial action of salivary enzymes that collectively contribute to oral health and protection. STD, can directly and indirectly affect mucous membranes, manifesting with characteristic diagnostic signs and lesions. Given their potential oral manifestations, dental professionals need a comprehensive understanding of STD. The findings of this review lay a foundation for comprehending several STDs, emphasizing the importance of physicians as well dental practitioners being open to discussing sexuality issues with patients and providing appropriate therapeutic interventions.

这篇综述为牙科医生提供了处理与性传播疾病(STD)相关的口腔病变的实用建议,提供了与临床相关的见解,以提高人们在日常实践中对这些疾病的认识。性传播疾病是通过无保护的阴道、肛门或口交感染的,由 30 多种不同类型的细菌、病毒和原生动物引起。唾液、精液、精液、阴道分泌物和月经血都可能是感染的载体,而完整的黏膜、唾液的稀释功能和唾液酶的抗菌作用则是病原微生物感染的防御屏障,它们共同促进了口腔健康和保护。性传播疾病可直接或间接影响粘膜,表现为特征性诊断体征和病变。鉴于其潜在的口腔表现,牙科专业人员需要对性传播疾病有一个全面的了解。本综述的研究结果为理解几种性传播疾病奠定了基础,强调了医生和牙科医生与患者坦诚讨论性问题并提供适当治疗干预的重要性。
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引用次数: 0
Dental bleaching: patient perception and satisfaction. 牙齿漂白:患者的感知和满意度。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-13 DOI: 10.23736/S2724-6329.24.04950-7
Francesco S Ludovichetti, Nicoletta Zerman, Edoardo Stellini, Giulia Zambon, Sergio Mazzoleni, Andrea Zuccon

Background: Teeth bleaching is a common practice performed by dental hygienists and dentists to correct aesthetic problems due to dental discoloration. Patients' opinions on this procedure may be different according to their personal experiences, expectations and individual sensitivities. The aim of this study is to assess the degree of satisfaction and related sensitivity of patients to professional and home bleaching treatment.

Methods: A questionnaire consisting of 12 multiple-choice questions was submitted to 625 subjects among general population. These were related to: 1) patient's age and whether the patient is a smoker; 2) personal satisfaction; and 3) post-treatment tooth sensitivity. Descriptive analyses of all variables in the questionnaire were performed, and statistical analyses between variables were carried out by Chi-square test and Fisher's Exact test.

Results: Of the people surveyed, 66% performed home bleaching, while the remaining performed the treatment in a dental office. Thirty-three percent of patients had previously undergone teeth bleaching and the 95.7% stated that they were satisfied with the treatment. Of these, only 36.4% reported experiencing postoperative hypersensitivity. Most patients (91.3%) received professional scaling before undergoing bleaching treatment.

Conclusions: Patient satisfaction with tooth whitening treatment can vary from patient to patient and represents a strong indicator of treatment efficacy and suitability. A proper communication, careful management and individualized patient assessment are key to maximizing satisfaction and ensuring a positive and fulfilling patient experience.

背景:牙齿漂白是牙科卫生员和牙科医生为矫正牙齿变色引起的美观问题而采取的一种常见做法。患者对这一过程的看法可能因个人经历、期望值和个人敏感性而有所不同。本研究旨在评估患者对专业和家庭漂白治疗的满意度和相关敏感性:方法:向 625 名普通人群发放了由 12 道选择题组成的调查问卷。这些问题涉及1)患者的年龄和是否吸烟;2)个人满意度;3)治疗后的牙齿敏感度。对问卷中的所有变量进行了描述性分析,并通过卡方检验(Chi-square test)和费雪精确检验(Fisher's exact test)对变量之间进行了统计分析:在接受调查的人中,66%的人在家中进行漂白,其余的人在牙科诊所进行治疗。33%的患者以前接受过牙齿漂白,95.7%的患者对治疗效果表示满意。其中只有 36.4% 的患者表示术后出现了过敏反应。大多数患者(91.3%)在接受漂白治疗前都接受了专业洗牙:患者对牙齿美白治疗的满意度因人而异,是衡量治疗效果和适宜性的重要指标。适当的沟通、细致的管理和个性化的患者评估是最大限度提高满意度、确保患者获得积极而充实的体验的关键。
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引用次数: 0
Salivary oxidative stress biomarkers in periodontitis-free smokers: a cross sectional study. 无牙周炎吸烟者的唾液氧化应激生物标志物:一项横断面研究。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-02 DOI: 10.23736/S2724-6329.24.04879-4
Mohammad S Alrashdan, Hisham Al-Shorman, Ahmed Al-Dwairi, Abubaker Qutieshat, Mahmoud K Al-Omiri

Background: Salivary oxidative stress has been extensively studied with attempts to correlate changes in the oxidative stress markers with local and systemic factors, including smoking. The objective of this study was to evaluate the influence of two forms of smoking, cigarettes and waterpipe smoking (WPS), on selected oxidative stress biomarkers in saliva.

Methods: Three groups of participants were enrolled into the study, controls (never smokers), cigarette smokers and WPS. Participants were clinically free from periodontitis and systemic conditions known to affect the saliva constituents. Unstimulated whole saliva samples were collected according to a standard protocol and concentrations of 8-hydroxy-2'-deoxyguanosine (8-OHdG), myeloperoxidase (MPO), malondialdehyde (MDA), total antioxidant capacity (TAC), and cortisol. The one-way ANOVA test was used to compare the levels of each oxidative stress biomarker between the three study groups and the hierarchical linear regression analysis was used to test the levels of salivary cortisol for prediction of other oxidative stress biomarkers. Significance levels were set at 95% confidence intervals and probability values ≤0.05.

Results: 8-OHdG was highest in WPS group (mean±SE 11,030.35±1829.16 pg/mL) while MDA and cortisol levels were highest in the cigarette smokers group (mean±SE 3.33±0.52 µM and 3.99±0.48 ng/mL, respectively) and MPO was highest in the control group (mean±SE 7.760±1.55 ng/mL). WPS group showed the highest TAC (mean±SE 0.3±0.03 mM). However, none of the tested makers reached a statistically significant difference.

Conclusions: Despite subtle changes in some biomarkers, the salivary oxidative stress does not appear to be significantly influenced by smoking habits in periodontitis-free smokers.

背景:人们对唾液氧化应激进行了广泛的研究,试图将氧化应激标志物的变化与包括吸烟在内的局部和全身因素联系起来。本研究的目的是评估香烟和水烟(WPS)这两种吸烟形式对唾液中某些氧化应激生物标志物的影响:研究共招募了三组参与者,即对照组(从不吸烟者)、吸烟者和水烟吸烟者。参与者在临床上没有牙周炎和已知会影响唾液成分的全身性疾病。按照标准方案收集未刺激的全唾液样本,并检测 8-羟基-2'-脱氧鸟苷(8-OHdG)、髓过氧化物酶(MPO)、丙二醛(MDA)、总抗氧化能力(TAC)和皮质醇的浓度。采用单因素方差分析来比较三个研究组之间各氧化应激生物标志物的水平,并采用层次线性回归分析来检验唾液皮质醇水平对其他氧化应激生物标志物的预测作用。显著性水平设定为 95% 置信区间,概率值≤0.05:8-OHdG在WPS组最高(mean±SE 11,030.35±1829.16 pg/mL),而MDA和皮质醇水平在吸烟者组最高(mean±SE分别为3.33±0.52 µM和3.99±0.48 ng/mL),MPO在对照组最高(mean±SE 7.760±1.55 ng/mL)。WPS 组的 TAC 值最高(mean±SE 0.3±0.03 mM)。然而,所有测试的制造商均未达到具有统计学意义的差异:结论:尽管某些生物标志物发生了微妙的变化,但在无牙周炎的吸烟者中,唾液氧化应激似乎并未受到吸烟习惯的显著影响。
{"title":"Salivary oxidative stress biomarkers in periodontitis-free smokers: a cross sectional study.","authors":"Mohammad S Alrashdan, Hisham Al-Shorman, Ahmed Al-Dwairi, Abubaker Qutieshat, Mahmoud K Al-Omiri","doi":"10.23736/S2724-6329.24.04879-4","DOIUrl":"10.23736/S2724-6329.24.04879-4","url":null,"abstract":"<p><strong>Background: </strong>Salivary oxidative stress has been extensively studied with attempts to correlate changes in the oxidative stress markers with local and systemic factors, including smoking. The objective of this study was to evaluate the influence of two forms of smoking, cigarettes and waterpipe smoking (WPS), on selected oxidative stress biomarkers in saliva.</p><p><strong>Methods: </strong>Three groups of participants were enrolled into the study, controls (never smokers), cigarette smokers and WPS. Participants were clinically free from periodontitis and systemic conditions known to affect the saliva constituents. Unstimulated whole saliva samples were collected according to a standard protocol and concentrations of 8-hydroxy-2'-deoxyguanosine (8-OHdG), myeloperoxidase (MPO), malondialdehyde (MDA), total antioxidant capacity (TAC), and cortisol. The one-way ANOVA test was used to compare the levels of each oxidative stress biomarker between the three study groups and the hierarchical linear regression analysis was used to test the levels of salivary cortisol for prediction of other oxidative stress biomarkers. Significance levels were set at 95% confidence intervals and probability values ≤0.05.</p><p><strong>Results: </strong>8-OHdG was highest in WPS group (mean±SE 11,030.35±1829.16 pg/mL) while MDA and cortisol levels were highest in the cigarette smokers group (mean±SE 3.33±0.52 µM and 3.99±0.48 ng/mL, respectively) and MPO was highest in the control group (mean±SE 7.760±1.55 ng/mL). WPS group showed the highest TAC (mean±SE 0.3±0.03 mM). However, none of the tested makers reached a statistically significant difference.</p><p><strong>Conclusions: </strong>Despite subtle changes in some biomarkers, the salivary oxidative stress does not appear to be significantly influenced by smoking habits in periodontitis-free smokers.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apoptotic effects of biodentine, calcium-enriched mixture (CEM) cement, ferric sulfate, and mineral trioxide aggregate (MTA) on human mesenchymal stem cells isolated from the human pulp of exfoliated deciduous teeth. 生物本汀、富钙混合物(CEM)水泥、硫酸铁和三氧化二铝矿物骨料(MTA)对从脱落的脱落牙齿的人牙髓中分离出来的人间质干细胞的凋亡效应。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-04 DOI: 10.23736/S2724-6329.24.04826-5
Bahareh Nazemi Salman, Mahshid Mohebbi Rad, Ehsan Saburi

Background: Preservation of primary teeth in children is highly important. Pulpotomy is a commonly performed treatment procedure for primary teeth with extensive caries. Thus, biocompatibility of pulpotomy agents is highly important. Biodentine, calcium enriched mixture (CEM) cement, ferric sulfate, and mineral trioxide aggregate (MTA) Angelus are commonly used for this purpose. Thus, this study aimed to assess the apoptotic effects of Biodentine, CEM cement, ferric sulfate, and MTA on stem cells isolated from the human pulp of exfoliated deciduous teeth.

Methods: In this in-vitro, experimental study, stem cells isolated from the human pulp of exfoliated deciduous teeth were exposed to three different concentrations of Biodentine, CEM cement, ferric sulfate, and MTA for different time periods. The cytotoxicity of the materials was evaluated by flow cytometry using the annexin propidium iodide (PI) kit. Data were analyzed by ANOVA and Tukey's test at P<0.05 level of significance.

Results: All four tested materials induced significantly greater apoptosis compared with the control group. The difference in cell apoptosis caused by the first concentration of ferric sulfate and MTA was not significant at 24 hours. In other comparisons, the cytotoxicity of ferric sulfate was significantly lower than that of other materials. Biodentine showed higher cytotoxicity than MTA at first; but this difference faded over time. The cytotoxicity of CEM cement was comparable to that of MTA. The highest cell viability was noted at 24 hours in presence of the minimum concentration of ferric sulfate. The lowest cell viability was noted at 72 hours in presence of the maximum concentration of CEM cement.

Conclusions: In comparison with other materials, ferric sulfate showed minimum cytotoxicity; the cytotoxicity of the three cements was comparable. It appears that the concentration of ferric sulfate and the composition of cements are responsible for different levels of cytotoxicity.

背景:保护儿童的乳牙非常重要。牙髓切断术是对有大面积龋齿的基牙常用的治疗方法。因此,牙髓切断剂的生物相容性非常重要。常用的牙髓切断剂有生物正丁(Biodentine)、富钙混合物(CEM)水泥、硫酸铁和三氧化二铝矿物骨料(MTA)Angelus。因此,本研究旨在评估 Biodentine、CEM 水泥、硫酸铁和 MTA 对从脱落牙齿的人类牙髓中分离出来的干细胞的凋亡作用:在这项体外实验研究中,从脱落牙齿的人类牙髓中分离出来的干细胞在不同时间段内暴露于三种不同浓度的 Biodentine、CEM 水泥、硫酸铁和 MTA。使用附件素碘化丙啶(PI)试剂盒,通过流式细胞术评估这些材料的细胞毒性。结果采用方差分析和 Tukey's 检验进行数据分析:与对照组相比,所有四种测试材料都能诱导细胞凋亡。在 24 小时内,第一浓度硫酸铁和 MTA 引起的细胞凋亡差异不显著。在其他比较中,硫酸铁的细胞毒性明显低于其他材料。生物硫化碱的细胞毒性起初高于 MTA,但随着时间的推移,这种差异逐渐减弱。CEM 水泥的细胞毒性与 MTA 相当。在存在最低浓度硫酸铁的 24 小时内,细胞存活率最高。结论:与其他材料相比,硫酸铁的细胞毒性最小;三种水泥的细胞毒性相当。硫酸铁的浓度和水泥的成分似乎是造成不同程度细胞毒性的原因。
{"title":"Apoptotic effects of biodentine, calcium-enriched mixture (CEM) cement, ferric sulfate, and mineral trioxide aggregate (MTA) on human mesenchymal stem cells isolated from the human pulp of exfoliated deciduous teeth.","authors":"Bahareh Nazemi Salman, Mahshid Mohebbi Rad, Ehsan Saburi","doi":"10.23736/S2724-6329.24.04826-5","DOIUrl":"10.23736/S2724-6329.24.04826-5","url":null,"abstract":"<p><strong>Background: </strong>Preservation of primary teeth in children is highly important. Pulpotomy is a commonly performed treatment procedure for primary teeth with extensive caries. Thus, biocompatibility of pulpotomy agents is highly important. Biodentine, calcium enriched mixture (CEM) cement, ferric sulfate, and mineral trioxide aggregate (MTA) Angelus are commonly used for this purpose. Thus, this study aimed to assess the apoptotic effects of Biodentine, CEM cement, ferric sulfate, and MTA on stem cells isolated from the human pulp of exfoliated deciduous teeth.</p><p><strong>Methods: </strong>In this in-vitro, experimental study, stem cells isolated from the human pulp of exfoliated deciduous teeth were exposed to three different concentrations of Biodentine, CEM cement, ferric sulfate, and MTA for different time periods. The cytotoxicity of the materials was evaluated by flow cytometry using the annexin propidium iodide (PI) kit. Data were analyzed by ANOVA and Tukey's test at P<0.05 level of significance.</p><p><strong>Results: </strong>All four tested materials induced significantly greater apoptosis compared with the control group. The difference in cell apoptosis caused by the first concentration of ferric sulfate and MTA was not significant at 24 hours. In other comparisons, the cytotoxicity of ferric sulfate was significantly lower than that of other materials. Biodentine showed higher cytotoxicity than MTA at first; but this difference faded over time. The cytotoxicity of CEM cement was comparable to that of MTA. The highest cell viability was noted at 24 hours in presence of the minimum concentration of ferric sulfate. The lowest cell viability was noted at 72 hours in presence of the maximum concentration of CEM cement.</p><p><strong>Conclusions: </strong>In comparison with other materials, ferric sulfate showed minimum cytotoxicity; the cytotoxicity of the three cements was comparable. It appears that the concentration of ferric sulfate and the composition of cements are responsible for different levels of cytotoxicity.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elucidating hematological profile and electrolyte balance in oral cancer patients. 阐明口腔癌患者的血液学特征和电解质平衡。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-02 DOI: 10.23736/S2724-6329.24.04902-7
Ishwarya Sundaravadivelu, Kaviyarasi Renu, Sankaran Kavitha, Veeraraghavan V Priya, Rengasamy Gayathri, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: Oral cancer is a serious health issue in both the developing and developed worlds, and it is one of the most common forms of cancer of the head and neck. In accordance with the 2017 World Health Organization classification, oral cancer can affect any part of the mouth, including the buccal mucosa, the front two-thirds of the tongue, the lip, the palate, the vestibule, the alveolus, the floor of the mouth, and the gingivae. Hematology and electrolyte balance have been proposed as tumor indicators and paths into cancer's genesis. Examining the patient's blood count and electrolyte levels in order to better understand their oral cancer.

Methods: Electrolyte abnormalities are common in cancer patients and may be caused by the disease itself or by treatment. Hyponatremia is the most frequent electrolyte problem in cancer patients, and it is typically caused by the syndrome of improper ADH secretion. Although electrolyte problems are associated with a worse prognosis for cancer patients, timely and effective therapy has the potential to enhance both short- and long-term results and quality of life. Hematological tests on patients with oral cancer, including differential cell count, white blood cell count, and hemoglobin level.

Results: Compared to healthy controls, oral cancer patients show statistically significant differences in a number of biochemical parameters, including electrolytes (sodium, P<0.05; potassium, P=0.89; chloride, P<0.05); differential count (neutrophils, P<0.05; basophils, P<0.05). A significant risk factor for cancer patients is an electrolyte imbalance, which has been linked to inappropriate anti-diabetic hormone release.

Conclusions: Clinicians will find these shifts in electrolytic level helpful in diagnosing and tracking oral cancer. Potentially malignant oral disorders and Oral squamous cell carcinoma may be better predicted using a combination of TLC, neutrophil, and lymphocyte counts, as shown in this study.

背景:口腔癌在发展中国家和发达国家都是一个严重的健康问题,也是头颈部最常见的癌症形式之一。根据 2017 年世界卫生组织的分类,口腔癌可影响口腔的任何部位,包括颊粘膜、舌的前三分之二、唇、腭、前庭、肺泡、口底和牙龈。血液学和电解质平衡被认为是肿瘤指标,也是了解癌症成因的途径。检查患者的血细胞计数和电解质水平是为了更好地了解他们的口腔癌:电解质异常在癌症患者中很常见,可能由疾病本身或治疗引起。低钠血症是癌症患者最常见的电解质问题,通常由 ADH 分泌失调综合征引起。虽然电解质问题与癌症患者的预后较差有关,但及时有效的治疗有可能提高短期和长期疗效以及生活质量。对口腔癌患者进行血液学检测,包括差异细胞计数、白细胞计数和血红蛋白水平:结果:与健康对照组相比,口腔癌患者在一些生化指标上有显著的统计学差异,包括电解质(钠、PConclusions):临床医生会发现这些电解水平的变化有助于诊断和追踪口腔癌。如本研究所示,结合 TLC、中性粒细胞和淋巴细胞计数可更好地预测潜在的恶性口腔疾病和口腔鳞状细胞癌。
{"title":"Elucidating hematological profile and electrolyte balance in oral cancer patients.","authors":"Ishwarya Sundaravadivelu, Kaviyarasi Renu, Sankaran Kavitha, Veeraraghavan V Priya, Rengasamy Gayathri, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04902-7","DOIUrl":"10.23736/S2724-6329.24.04902-7","url":null,"abstract":"<p><strong>Background: </strong>Oral cancer is a serious health issue in both the developing and developed worlds, and it is one of the most common forms of cancer of the head and neck. In accordance with the 2017 World Health Organization classification, oral cancer can affect any part of the mouth, including the buccal mucosa, the front two-thirds of the tongue, the lip, the palate, the vestibule, the alveolus, the floor of the mouth, and the gingivae. Hematology and electrolyte balance have been proposed as tumor indicators and paths into cancer's genesis. Examining the patient's blood count and electrolyte levels in order to better understand their oral cancer.</p><p><strong>Methods: </strong>Electrolyte abnormalities are common in cancer patients and may be caused by the disease itself or by treatment. Hyponatremia is the most frequent electrolyte problem in cancer patients, and it is typically caused by the syndrome of improper ADH secretion. Although electrolyte problems are associated with a worse prognosis for cancer patients, timely and effective therapy has the potential to enhance both short- and long-term results and quality of life. Hematological tests on patients with oral cancer, including differential cell count, white blood cell count, and hemoglobin level.</p><p><strong>Results: </strong>Compared to healthy controls, oral cancer patients show statistically significant differences in a number of biochemical parameters, including electrolytes (sodium, P<0.05; potassium, P=0.89; chloride, P<0.05); differential count (neutrophils, P<0.05; basophils, P<0.05). A significant risk factor for cancer patients is an electrolyte imbalance, which has been linked to inappropriate anti-diabetic hormone release.</p><p><strong>Conclusions: </strong>Clinicians will find these shifts in electrolytic level helpful in diagnosing and tracking oral cancer. Potentially malignant oral disorders and Oral squamous cell carcinoma may be better predicted using a combination of TLC, neutrophil, and lymphocyte counts, as shown in this study.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periodontal host-modulation therapy with avocado/soybean unsaponifiables in rats with arthritis. 用牛油果/大豆不皂化物对患有关节炎的大鼠进行牙周宿主调节疗法。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-04 DOI: 10.23736/S2724-6329.24.04854-X
Guilherme J Lopes de Oliveira, Jackeline do Nascimento Tsurumaki, Mauricio A Aroni, Elcio Marcantonio, Rosemary A Marcantonio

Background: The aim of this study was to evaluate the effect of the avocado/soybean unsaponifiables (ASU) in the treatment of induced periodontitis in rats with experimental arthritis.

Methods: Sixty rats were randomly assigned to 4 groups according to the type of treatment and the systemic condition of the animals: CTR-S: healthy animals in which saline solution (SS) was administered; ASU-S: healthy animals in which ASU (0.6 mg/kg) was administered; AR/ASU-S: animals with induced arthritis in which ASU was administered; AR-S: animals with induced arthritis in which SS was administered. Periodontitis was induced by ligatures, maintained for 15 days. Subsequently, the treatment was performed by scaling with hand instruments. The SS and ASU were administered daily by gavage until euthanasia of the animals that occurred at 7, 15 or 30 days after the scaling procedure (N.=5 animals/group). Bone resorption, inflammatory infiltrate composition, and osteoclastogenesis were assessed.

Results: The AR-S group had greater bone loss, smaller amounts of fibroblasts and larger amounts of inflammatory cells than all other groups. In addition, the AR-S group had greater osteoclastogenesis in relation to the healthy animal groups.

Conclusions: The use of ASU improved the healing pattern after treatment for experimental periodontitis in animals with arthritis reducing the periodontal bone loss.

背景:本研究的目的是评估牛油果/大豆不皂化物(ASU)治疗实验性关节炎大鼠诱发牙周炎的效果:根据治疗类型和动物的全身状况,将 60 只大鼠随机分为 4 组:CTR-S:注射生理盐水(SS)的健康动物;ASU-S:注射ASU(0.6 mg/kg)的健康动物;AR/ASU-S:注射ASU的诱发关节炎动物;AR-S:注射SS的诱发关节炎动物。通过结扎诱发牙周炎,并维持 15 天。随后,用手工工具进行洗牙治疗。每天灌胃注射 SS 和 ASU,直到动物在洗牙后 7、15 或 30 天安乐死为止(每组 5 只动物)。对骨吸收、炎症浸润成分和破骨细胞生成进行了评估:结果:与其他各组相比,AR-S 组骨质流失更严重,成纤维细胞数量更少,炎症细胞数量更多。此外,与健康动物组相比,AR-S 组的破骨细胞生成更多:使用 ASU 可改善关节炎动物实验性牙周炎治疗后的愈合模式,减少牙周骨质流失。
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引用次数: 0
L.O.V.E.R.R.S.: a conceptual framework to shape your purpose and a life of fulfilment. L.O.V.E.R.R.S.:塑造你的目标和充实生活的概念框架。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-03-18 DOI: 10.23736/S2724-6329.23.04904-5
Alessandro Quaranta, Wang L Hui
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引用次数: 0
The knowledge, attitude and perceived confidence in handling medical emergencies among dental students. 牙科学生在处理医疗紧急情况方面的知识、态度和信心。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-15 DOI: 10.23736/S2724-6329.23.04865-9
Mahesh Shenoy K, Talal M Alkhelaiwi, Abdullah H Alasiri, Badr R Hejazi, Khaled R Alkathiri, Shahzeb H Ansari, Diana Russo, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: According to Centers for Medicare and Medicaid Services HHS 2017, when a medical disease suddenly manifests itself with acute symptoms of sufficient intensity (including extreme pain) endangering the patient's health, seriously impairing body functions or bringing an organ or its portion to be seriously dysfunctional, a medical emergency has occurred. Therefore, this study aimed to assess the knowledge, attitude, and perceived confidence in handling medical emergencies among dental students by the means of conducting this investigation.

Methods: This is a cross-sectional study conducted among the different hierarchies of dentists of Riyadh using an online survey; 387 dentists from varying clinical levels (9 to 12) were included in this study. The questionnaire used for this study consisted of questions related to demographic data followed by questions including knowledge, attitude, and confidence towards handling medical emergencies in clinics.

Results: In this study, male participants represented 64.4% and female subjects represented 35.6% of the total population. Most of the undergraduates were in their 5th year of dentistry school and accounted for 36.9%, followed by 6th year 36.2% and 4th year 26.8%. 67.1% of the undergraduates never encountered any medical emergency during their study, while 32.9% encountered an emergency. Furthermore, 58.4% of the analyzed subjects recorded medical history thoroughly, while priority in an emergency was adrenaline, with a percentage of 45%. For the patient suffering syncope the Trendelenburg position was chosen. Also, the first action choice with unresponsive patients was CPR.

Conclusions: In the present study, the findings revealed that the majority of the population never encountered an emergency in their career, but their knowledge about drug priority and patient's position was good. Most of them do not measure vital signs routinely; specifically, females do not usually measure, while males measure when needed. About Basic Life Support (BLS), participants took BLS or were interested in taking it in the future; furthermore, in group population, both have taken it and are interested in further carrying it.

背景:根据美国医疗保险和医疗补助服务中心 HHS 2017 年的规定,当内科疾病突然表现出足够强度的急性症状(包括极度疼痛)危及患者健康、严重损害身体功能或使器官或其部分严重功能障碍时,即发生了医疗紧急情况。因此,本研究旨在通过开展这项调查,评估牙科学生在处理医疗紧急情况方面的知识、态度和感知信心:本研究是一项横断面研究,采用在线调查的方式在利雅得不同级别的牙科医生中进行;387 名来自不同临床级别(9 至 12 级)的牙科医生参与了本研究。本研究使用的调查问卷包括与人口统计学数据相关的问题,其后的问题包括在诊所处理医疗紧急情况的知识、态度和信心:在这项研究中,男性受试者占总人数的 64.4%,女性受试者占总人数的 35.6%。大多数本科生是口腔医学院的五年级学生,占 36.9%,其次是六年级学生,占 36.2%,四年级学生占 26.8%。67.1%的本科生在学习期间从未遇到过任何医疗紧急情况,32.9%的本科生遇到过紧急情况。此外,58.4%的分析对象详细记录了病史,而在紧急情况下优先使用肾上腺素的比例为 45%。晕厥患者选择 Trendelenburg 体位。此外,对于反应迟钝的患者,第一选择是心肺复苏:本研究的结果显示,大多数人在其职业生涯中从未遇到过紧急情况,但他们对药物优先顺序和患者体位的了解程度较高。他们中的大多数人并不经常测量生命体征;具体而言,女性通常不测量,而男性在需要时才测量。关于基本生命支持(BLS),参与者参加过 BLS 或有兴趣在将来参加;此外,在群体中,既有参加过 BLS 的,也有有兴趣继续参加的。
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Minerva dental and oral science
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