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Medico-legal considerations in immediate loading implantology: risks, responsibilities, and best practices. 即刻植入种植体的医疗法律考虑因素:风险、责任和最佳实践。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-10-28 DOI: 10.23736/S2724-6329.24.05129-5
Michele A Karaboue, Eleonora Lo Muzio, Maria E Bizzoca, Karidia Karaboue, Swapnil Saini, Francesco Pettini, Michele Di Cosola, Michele Covelli, Lynn Almasri, Giorgia V Lacasella

The field of immediate loading implantology has grown rapidly, offering quicker solutions for prosthetic rehabilitation. However, the complexity of this technique raises significant medico-legal concerns regarding patient safety, treatment planning, and professional liability. These issues are particularly relevant in elective procedures where failure could lead to litigation. A comprehensive review of current literature, including clinical studies, legal rulings, and malpractice claims, was conducted to assess the legal implications of immediate loading implantology. The analysis focused on professional liability, patient consent, and complications during treatment. The evidence indicates that a high standard of care, including detailed preoperative planning, risk assessment, and clear patient communication, is essential in minimizing legal risks. Malpractice claims often arise from inadequate patient information or failure to follow established protocols. Proper documentation of informed consent and adherence to evidence-based dentistry (EBD) guidelines are crucial to protect both patients and practitioners. Immediate loading implantology offers numerous benefits, but it requires meticulous planning and patient management to avoid medico-legal issues. Ensuring comprehensive patient consent and following evidence-based practices are key to reducing professional liability and improving outcomes. Further studies should explore standardized protocols for reducing complications and legal disputes in implantology.

即刻负重种植领域发展迅速,为修复康复提供了更快捷的解决方案。然而,这项技术的复杂性引发了有关患者安全、治疗计划和职业责任的重大医疗法律问题。这些问题在选择性手术中尤为突出,因为手术失败可能导致诉讼。为了评估即刻负重种植的法律影响,我们对当前的文献进行了全面的回顾,包括临床研究、法律判决和不当索赔。分析的重点是职业责任、患者同意和治疗过程中的并发症。证据表明,高标准的护理,包括详细的术前计划、风险评估和清晰的患者沟通,对于最大限度地降低法律风险至关重要。渎职索赔往往源于患者信息不足或未遵循既定方案。正确记录知情同意和遵守循证牙科(EBD)指南对于保护患者和医生都至关重要。即刻装填种植技术有很多优点,但需要精心策划和管理患者,以避免医疗法律问题。确保获得患者的全面同意并遵循循证实践是减少职业责任和提高疗效的关键。进一步的研究应探索标准化方案,以减少种植过程中的并发症和法律纠纷。
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引用次数: 0
Relationship between the healing rate of post-extraction sites and the quantity of platelets present in the blood: a retrospective observational study. 拔牙后部位的愈合率与血液中血小板数量的关系:一项回顾性观察研究。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-09-27 DOI: 10.23736/S2724-6329.24.05049-6
Maria E Bizzoca, Fabrizio Bambini, Maria L Garo, Alessio Marani, Roberto Rossi, Francesco Sampalmieri, Lucia Memè

Background: In daily surgical practice, the dentist deals with various types of oral surgery. At the first visit, the patient fills out a questionnaire about their state of health. If the questionnaire does not reveal any particular hematological problems, no special tests are usually required to determine the platelet count. The aim of this prospective study was to evaluate the healing process of patients and its correlation with platelet levels before surgery.

Methods: A total of 50 patients were included in whom blood chemistry tests were performed with special attention to the platelet count and before their mandibular eights were extracted .The type of healing (EHI) and pain on the second day (VAS) were assessed using methods validated in the literature.

Results: After the EHI and VAS scores were noted in the medical records, envelopes containing the platelet scores of the previously requested blood samples, which were not read at the time of observation, were opened. An increase in EHI scores and a decrease in VAS scores was observed that were statistically significantly correlated with increasing platelet scores.

Conclusions: These results suggest that the dentist should request chemistry tests on preoperative blood, especially if the patient is to undergo a particularly demanding oral surgical procedure, such as implants, guided bone regeneration or complex extractions.

背景:在日常手术实践中,牙医要处理各种类型的口腔手术。首次就诊时,患者会填写一份有关其健康状况的问卷。如果问卷没有显示任何特殊的血液学问题,通常不需要进行特殊检查来确定血小板计数。这项前瞻性研究旨在评估患者的愈合过程及其与术前血小板水平的相关性:方法:共纳入 50 名患者,在拔下颌八爪鱼之前对其进行血液化学检查,并特别关注血小板计数,采用文献中验证的方法评估愈合类型(EHI)和第二天的疼痛(VAS):在病历中记录了 EHI 和 VAS 评分后,打开了装有之前申请的血样血小板评分的信封,这些血样在观察时并未读取。结果发现,EHI 分数的增加和 VAS 分数的减少与血小板分数的增加在统计学上有显著相关性:这些结果表明,牙医应要求对术前血液进行化学检测,尤其是当患者要接受要求特别高的口腔外科手术时,如种植、引导骨再生或复杂的拔牙。
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引用次数: 0
Insertion axis in removable prosthesis: a preliminary report. 可摘义齿的插入轴:初步报告。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-09-27 DOI: 10.23736/S2724-6329.24.04973-8
Saverio Ceraulo, Paolo Caccianiga, Antonio Barbarisi, Gianluigi Caccianiga, Roberto Biagi

Background: Removable partial denture (RPD) is still a widely used prosthesis today to solve non-implant cases, despite its aesthetic contraindications. The aim of the following work is to evaluate how much the communication and explanation to the patient of the insertion axis of the removable partial prosthesis in the periodontium and teeth has an impact on his degree of acceptance of the aesthetic limits of this prosthesis.

Methods: For this study, 150 patients were examined from 10 dentists, 5 in Lombardy and 5 in Sicily, using inclusion criteria and exclusion criteria. All selected patients required removable partial dentures. The data was obtained by completing 2 questionnaires, at three different times, at prosthesis delivery, at 6 and 12 months.

Results: Questionnaires highlighted overlapping data in the two regions and a total absence of communication of the insertion axis by the dental technician laboratories was highlighted with a percentage of 100%. 28% of the patients complained of pain during the insertion of the prosthesis at 12 months and 39.33% of patients had mobility of remaining teeth with clasps at 12 months. All patients experienced no discomfort, and no important data were reported at the first 6-month follow-up.

Conclusions: For mobile partial dentures, respecting the insertion axis can improve the predictability of the periodontal tissue and the resistance of the remaining teeth with clasps. The drawing of an arrow in the model shows the insertion axis of the prosthesis. It would be desirable to include information regarding the insertion axis and advice for the management of the removable partial denture in the first days of use in the declaration of conformity given to the doctor and to thepatient, in the indications section. It can be said that correct insertion of the removable partial denture, helped by verbal and written instructions from the doctor, can reduce possible periodontal alterations of the remaining teeth, by eliminating spurious stresses during insertion and removal of the prosthesis.

背景:可摘局部义齿(RPD)尽管有美学禁忌症,但目前仍是解决非种植病例的一种广泛使用的修复体。以下研究的目的是评估与患者沟通并向其解释可摘局部义齿在牙周和牙齿中的插入轴对其接受该义齿美学限制的程度有多大影响:在这项研究中,根据纳入标准和排除标准,对 10 名牙医(5 名在伦巴第,5 名在西西里)的 150 名患者进行了检查。所有被选中的患者都需要可摘局部义齿。在义齿交付、6 个月和 12 个月的三个不同时间,通过填写两份调查问卷获得数据:调查问卷显示,两个地区的数据存在重叠,牙科技工室完全没有就插入轴进行沟通,比例高达 100%。28%的患者在 12 个月时抱怨在安装假牙时感到疼痛,39.33%的患者在 12 个月时剩余的牙齿可以活动。所有患者均无不适感,在首次 6 个月的随访中也未报告任何重要数据:结论:对于活动局部义齿来说,尊重插入轴线可以提高牙周组织的可预测性和余留牙的卡环阻力。模型中的箭头表示义齿的插入轴。在给医生和患者的合格声明中,最好在适应症部分包括有关插入轴的信息和可摘局部义齿使用初期的管理建议。可以说,在医生的口头和书面指导帮助下正确安装可摘局部义齿,可以消除安装和摘除义齿过程中的虚假应力,从而减少剩余牙齿可能出现的牙周改变。
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引用次数: 0
Early wound healing in guided bone regeneration procedures using sodium hyaluronate and a pool of amino acids: a randomized clinical trial. 使用透明质酸钠和氨基酸池引导骨再生手术的早期伤口愈合:随机临床试验。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-11-20 DOI: 10.23736/S2724-6329.24.05095-2
Daniele Cardaropoli, Lorenzo Tamagnone, Luigi Laino, Lorena Gaveglio

Background: Soft tissue healing is of paramount importance when guided bone regeneration techniques are used, as early exposure of the membrane could affect the results.

Methods: In this randomized clinical trial, enrolling 20 patients, a gel rich in hyaluronic acid and amino acids was used to promote wound healing after a ridge augmentation procedure. The Early Wound Healing Index - EHS was used to assess soft tissue healing by primary intention following surgery at 1, 3, 7 and 14 days.

Results: Results showed faster tissue healing when hyaluronic acid mixed with amino acids was used, and also a lower perception of pain by patients measured with a VAS scale.

Conclusions: These data suggest the creation of larger research studies that can support the use of biologics for early soft tissue healing.

背景:在使用引导骨再生技术时,软组织愈合至关重要,因为早期的骨膜暴露可能会影响效果:在这项随机临床试验中,20 名患者使用了一种富含透明质酸和氨基酸的凝胶来促进隆鼻术后的伤口愈合。采用早期伤口愈合指数(EHS)评估术后1、3、7和14天的软组织愈合情况:结果表明,使用混合了氨基酸的透明质酸时,组织愈合速度更快,使用 VAS 量表测量的患者疼痛感也更低:这些数据建议开展更大规模的研究,以支持生物制剂用于早期软组织愈合。
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引用次数: 0
Diagnosis of odontogenic keratocysts and non-keratocysts using edge attention convolution neural network. 利用边缘注意卷积神经网络诊断牙源性角化囊肿和非角化囊肿
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-09-27 DOI: 10.23736/S2724-6329.24.04874-5
Nivedan Yakolli, Divya B Shivanna, Roopa S Rao, Shankargouda Patil, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: The study's objective was to develop an automated method for a histopathology recognition model for odontogenic keratocysts (OKC) and non-keratocyst (Non-KC) in jaw cyst sections stained with hematoxylin (H) and eosin (E) on a tiny bit of incisional biopsy prior to surgery.

Methods: This hastens the speed and precision of diagnosis to patients. Also, navigates the clinicians with the therapeutic doctrine. To build such a system and to increase the accuracy of the existing models, the edge attention CNN model with Keras functional API was implemented which efficiently analyzes the texture information of the images. Approximately 2861 microscopic images at a 40X magnification were taken from 54 OKC, 23 Dentigerous cysts (DC), and 20 Radicular cysts.

Results: The model was trained using both RGB and canny edge-detected images. The model gave a good accuracy of 96.8%, which is suitable for real-time. Histopathological images are better analyzed through textural features. The proposed edge attention CNN highlights the edges, making texture analysis more precise.

Conclusions: The suggested method will work for OKC and Non-KC diagnosis automation systems. The use of a whole slide imaging scanner has the potential to increase accuracy and remove human bias.

研究背景该研究的目的是开发一种组织病理学自动识别模型方法,用于识别手术前切口活检切片中经苏木精(H)和伊红(E)染色的牙源性角化囊肿(OKC)和非角化囊肿(Non-KC):这将加快患者诊断的速度和准确性。方法:这加快了患者诊断的速度和准确性,也为临床医生的治疗理论提供了导航。为了建立这样一个系统并提高现有模型的准确性,我们使用 Keras 功能 API 实现了边缘注意 CNN 模型,该模型可有效分析图像的纹理信息。我们从 54 个 OKC、23 个齿状囊肿(DC)和 20 个根状囊肿中提取了约 2861 张放大 40 倍的显微图像:使用 RGB 和 canny 边缘检测图像对模型进行了训练。该模型的准确率高达 96.8%,适合实时分析。通过纹理特征可以更好地分析组织病理学图像。提出的边缘关注 CNN 可以突出边缘,使纹理分析更加精确:结论:建议的方法适用于 OKC 和非 KC 诊断自动化系统。使用整张切片成像扫描仪有可能提高准确性并消除人为偏差。
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引用次数: 0
Biomechanical considerations of chemical structure and biosafety of current ceramic biomaterials for dentistry: review and outlook of the current state of the art. 当前牙科用陶瓷生物材料化学结构和生物安全性的生物力学考虑因素:技术现状回顾与展望。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-10-08 DOI: 10.23736/S2724-6329.24.05093-9
Gennaro Musella, Andrea Ballini, Michele Di Cosola, Alessandro Motta, Tommaso Dai Prà, Fariba Esperouz, Mario Dioguardi, Lorenzo Lo Muzio, Gaetano Illuzzi, Maria E Bizzoca

Biomaterial refers to any material, non-pharmaceutical or combination of substances of synthetic or natural origin used for any period independently or as part of a system for the purpose of healing, assisting the growth or replacement of tissues, organs or functions of the body. It is an unsustainable material that interacts with biological systems. Before being produced a biomaterial goes through a sequence of steps, which includes: 1) the definition of the problem that the material will be called to solve (treatment, replacement of the instrument, aesthetic reasons); 2) design of the device, composition and control of materials (mechanical properties, toxicity, biological response, corrosion resistance, interaction with proteins, cells and tissues), manufacture, sterilization and standardization; 3) control of the device (in experimental animals, in vitro) clinical studies, studies; and 4) monitor its long-term use in vivo, in vitro and in patients. Research for ceramic materials is evolving and because they can be porous or glassy, they find applications in medicine and biotechnology, as they can be used as fillers, covering materials and scaffolds. Therefore, ceramic biomaterials are widely used not only in the field of orthopedic and maxillofacial surgery but also in dentistry as for dental prostheses. Materials monitoring technologies allow us to monitor the three-dimensional development in space, as well as imperfections or micro-cracks in the ceramic.

生物材料是指任何材料、非药物或合成或天然来源的物质组合,可在任何时期单独使用或作为一个系统的一部分使用,以达到治疗、辅助生长或替代人体组织、器官或功能的目的。它是一种与生物系统相互作用的不可持续材料。生物材料在生产之前需要经过一系列步骤,其中包括1)确定该材料要解决的问题(治疗、替代器械、美学原因);2)设计装置、材料的组成和控制(机械性能、毒性、生物反应、耐腐蚀性、与蛋白质、细胞和组织的相互作用)、制造、消毒和标准化;3)控制装置(在实验动物、体外)的临床研究;4)监测其在体内、体外和病人体内的长期使用情况。对陶瓷材料的研究正在不断发展,由于陶瓷材料可以是多孔的或玻璃状的,它们在医学和生物技术领域都有应用,因为它们可以用作填充物、覆盖材料和支架。因此,陶瓷生物材料不仅被广泛应用于整形外科和颌面外科领域,还被广泛应用于牙科领域的义齿修复。通过材料监测技术,我们可以监测空间的三维发展,以及陶瓷中的缺陷或微裂缝。
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引用次数: 0
An in-vivo study on the effect of head orientation in the measurement of anthropometric points in stereophotogrammetry. 立体摄影测量中头部方向对人体测量点测量影响的活体研究。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-09-06 DOI: 10.23736/S2724-6329.24.04852-6
Marco Di Blasio, Giuseppe Minervini, Marzia Segù, Giuseppe Pedrazzi, Alberto Di Blasio, Diana Cassi, Marco Cicciù, Bendetta Vaienti

Background: It is well known that in bidimensional photography the orientation of the head is fundamental to obtain a correct reproduction of the subject. Even minimal errors in yaw, roll and pitch of the head can be cause of unreliability of the photography itself. This is not the case in three-dimensional photography in which head positioning may have no influence on the reliability of the results since on the computer the 3D reconstruction of the face can be oriented as desired, allowing any small errors to be corrected. The authors, in a previous in-vitro study, demonstrated this using a mannequin of the head. In the present study, the Authors repeat the study in vivo to verify any differences.

Methods: Seventeen anthropometric points were marked on the face of a young adult female (26 years old) with eyeliner. Images of the face were then acquired with a stereo-photogrammetric system (Face Shape 3D MaxiLine) in natural head position and with varying degrees of roll, pitch and yaw. The anthropometric points marked on the skin were then recognized and marked on a digital software (Viewbox, dHAL Software, 6 Menandrou Street, Kifissia 14561, Greece) on each individual image. 14 linear distances between these points were measured using the same software.

Results: The linear distances of these points in the stereophotos taken at centered positions were then compared with those taken with different degrees of roll, pitch and yaw. This study confirms previous results obtained in vitro regarding the presence of areas of non-equivalence (P<0.05) when comparing the frontal and lateral regions of the face at various angles.

Conclusions: However, it introduces important suggestions on the collection of data from specific anthropometric points. If these points are to be assessed, the medical staff will have to take special precautions to obtain reliable images.

背景:众所周知,在二维摄影中,头部的方向是正确再现拍摄对象的基础。即使头部在偏航、滚动和俯仰方面的误差很小,也会导致摄影本身不可靠。而三维摄影则不同,在三维摄影中,头部定位可能不会影响拍摄结果的可靠性,因为在计算机上,面部的三维重建可以按照需要调整方向,任何微小的误差都可以得到纠正。在之前的体外研究中,作者使用头部人体模型证明了这一点。在本研究中,作者重复了体内研究,以验证任何差异:方法:用眼线笔在一名年轻成年女性(26 岁)的面部标出 17 个人体测量点。然后用立体摄影测量系统(Face Shape 3D MaxiLine)在自然头位和不同程度的滚动、俯仰和偏航下采集面部图像。然后用数字软件(Viewbox, dHAL Software, 6 Menandrou Street, Kifissia 14561, Greece)在每张图像上识别并标记皮肤上的人体测量点。使用同一软件测量了这些点之间的 14 个线性距离:然后,将这些点在居中位置拍摄的立体照片中的线性距离与不同滚动、俯仰和偏航度拍摄的立体照片进行比较。这项研究证实了之前在体外获得的关于存在非等效区域(PConclusions)的结果:不过,该研究也对从特定人体测量点收集数据提出了重要建议。如果要对这些点进行评估,医务人员必须采取特别的预防措施,以获得可靠的图像。
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引用次数: 0
AI-based prediction and classification of root caries using radiographic images. 基于人工智能的根龋预测和分类(使用放射影像)。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-20 DOI: 10.23736/S2724-6329.24.04967-2
Pradeep K Yadalam, Jeevitha Manickavasagam, Trisha Sasikumar, Maria M Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: Root surface caries, commonly known as root decay, is a common dental disorder that affects tooth roots. Like enamel-based tooth decay, root caries attack exposed root surfaces caused by gum recession or periodontal disease. Older persons with gum recession, tooth loss, or poor oral hygiene may be more likely to develop this disorder. Dental root caries must be diagnosed early to improve treatment and prevention. This research will examine radiographic image-based AI-based root caries prediction algorithms.

Methods: Saveetha Dental College supplied 200 root surface radiographs. An expert dentist and dental radiologist confirmed one hundred teeth with root caries and 100 without. Edited and segmented radiographic images. Orange, a machine learning squeeze net embedding model with Naive Bayes, Logistic Regression, and neural networks, was used to assess prediction accuracy. Training and test data were split 80/20. Cross-validation, confusion matrix, and ROC analysis assessed model performance. This study examined precision and recall.

Results: Naïve bayes and logistic regression have 96% and 100% accuracy, but class accuracy is -94% and 100% in image classification of root caries was seen.

Conclusions: AI-based root caries prediction utilizing radiographic images would improve dental care by diagnosing and treating early, accurately, and personalized. With appropriate deployment, research, and ethics, AI integration in dentistry could benefit practitioners and patients. Dental professionals and AI experts must work together to maximize this new technology.AI integration in dentistry can significantly improve root caries diagnosis and treatment by predicting root caries using radiographic images. This early detection reduces treatment need and time. Collaboration between dental professionals and AI experts is crucial for maximizing benefits.

背景:根面龋,俗称蛀牙,是一种影响牙根的常见牙科疾病。与基于珐琅质的蛀牙一样,根面龋也会攻击因牙龈萎缩或牙周病而暴露的牙根表面。牙龈萎缩、牙齿脱落或口腔卫生不良的老年人可能更容易患上这种疾病。牙根龋必须及早诊断,以改善治疗和预防。本研究将研究基于放射影像的人工智能根龋预测算法:方法:Saveetha牙科学院提供了200张牙根表面X光片。牙科专家和牙科放射科医生确认 100 颗牙齿有龋齿,100 颗没有。对放射影像进行编辑和分割。Orange 是一种机器学习挤压网嵌入模型,采用 Naive Bayes、逻辑回归和神经网络来评估预测准确性。训练数据和测试数据各占 80/20。交叉验证、混淆矩阵和 ROC 分析评估了模型的性能。本研究考察了精确度和召回率:结果:奈夫贝叶斯和逻辑回归的准确率分别为 96% 和 100%,但龋齿图像分类的类准确率分别为-94% 和 100%:结论:基于人工智能的根龋预测利用放射影像将通过早期、准确和个性化的诊断和治疗改善牙科护理。通过适当的部署、研究和道德规范,人工智能与牙科的结合将使从业人员和患者受益。牙科专业人员和人工智能专家必须通力合作,最大限度地利用这项新技术。将人工智能整合到牙科中,通过使用放射影像预测根龋,可以显著改善根龋的诊断和治疗。这种早期检测可减少治疗需求和时间。牙科专业人员和人工智能专家之间的合作对于实现效益最大化至关重要。
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引用次数: 0
Determination of red blood cell parameters for signs of iron deficiency anemia in patients with oral diseases. 检测口腔疾病患者缺铁性贫血迹象的红细胞参数。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-20 DOI: 10.23736/S2724-6329.24.04907-6
Kavithaa Rajasekaran, Kaviyarasi Renu, Kavitha Sankaran, Vishnu Priya Veeraraghavan, Gayathri Rengasamy, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: A lack of healthy red blood cells such as iron deficiency frequently consequences as anemia. In expectant women, iron deficiency increases the risk of developmental delays in the fetus. It is utilized to regenerate red blood cells (RBC), which determines the storage and transport of oxygen in the body. As for oral symptoms and indications, it has an inclusive of atrophic glossitis, oral mucosa atrophy, and oral mucosa tenderness or a sensation with burning in mouth. The objective is to determine RBC parameters for iron deficiency anemia (IDA) symptoms in oral disease patients.

Methods: Normal and oral disease patients' blood is collected in a 2-mL EDTA vial for the hematology analyzer. With file number SRB/SDC/UG-2155/22/493, the institutional ethical approval committee approved this study: 10 controls (without anemia) and 10 patients with oral disease (with anemia).

Results: In oral disease patients with anemia, a decreased hemoglobin level is observed. In this study, nearly all anemic patients have IDA. In IDA, the RBC count decreases, the MCV decreases, the MCH decreases, and the RDW rises. We have analyzed various iron deficiency anemia indices. Ricercari and Eshani demonstrate a significant change in it.

Conclusions: In predicting iron deficiency anemia, our results indicate that oral patients have significant differences in hematological parameters that are individual. It demonstrates that oral disease patients are developing iron deficiency anemia than controls (healthy). Additionally, the discrimination indices reveal that they do not have hemoglobinopathies but rather iron deficiencies. Oral manifestations are more prevalent in Iron deficiency anemia (IDA) patients than in healthy patients, according to our findings.

背景:缺乏健康的红细胞(如缺铁)经常会导致贫血。孕妇缺铁会增加胎儿发育迟缓的风险。铁是人体必需的微量元素,用于再生红细胞(RBC),而红细胞决定着氧气在体内的储存和运输。至于口腔症状和适应症,它包括萎缩性舌炎、口腔粘膜萎缩、口腔粘膜触痛或口腔烧灼感。本研究旨在确定口腔疾病患者缺铁性贫血(IDA)症状的红细胞参数:方法:将正常人和口腔疾病患者的血液收集在 2 mL EDTA 瓶中,供血液分析仪使用。机构伦理审批委员会批准了本研究,文件号为 SRB/SDC/UG-2155/22/493:10名对照组(无贫血)和10名口腔疾病患者(贫血):结果:在贫血的口腔疾病患者中,可以观察到血红蛋白水平下降。在这项研究中,几乎所有贫血患者都患有 IDA。在 IDA 患者中,红细胞计数减少,MCV 下降,MCH 下降,RDW 上升。我们分析了各种缺铁性贫血指数。Ricercari 和 Eshani 证明了其显著变化:在预测缺铁性贫血方面,我们的研究结果表明,口腔疾病患者的血液学指标存在明显的个体差异。这表明口腔疾病患者比对照组(健康人)更容易患缺铁性贫血。此外,辨别指数显示,他们没有血红蛋白病,而是缺铁。根据我们的研究结果,缺铁性贫血(IDA)患者的口腔表现比健康患者更为普遍。
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引用次数: 0
The pyogenic granuloma: localization, incidence, clinical features. 化脓性肉芽肿:定位、发病率、临床特征。
IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-20 DOI: 10.23736/S2724-6329.24.05075-7
Afrah A Aldelaimi, Hamid H Enezei, Thamer Y Humadi, Khalil A Mohammed, Tahrir N Aldelaimi, Maria M Marrapodi, Gabriele Cervino, Giuseppe Minervini

Background: A pyogenic granuloma (PG) represents a swiftly proliferating benign vascular tumor situated in the skin or subcutaneous tissue, commonly observed as a reactive lesion in the orofacial area. This research intended to scrutinize the clinicopathological characteristics of pyogenic granulomas in the oral and maxillofacial region.

Methods: Seventy two participants, comprising 24 men (33%) and 48 women (67%), underwent surgical ablation of pyogenic granuloma in oral and maxillofacial regions utilizing 940nm and 980nm diode lasers. Standard tissue processing procedures were applied to all specimens, with subsequent slicing of paraffin-embedded blocks at a 5µm thickness for H & E staining. A microscopic examination via light microscopy was conducted on all slides to confirm the diagnosis.

Results: All cases underwent pyogenic granuloma surgical laser ablation, with 53 individuals (74%) aged 30 years or younger, 19 (26%) aged 30 years or more, 52 (72%) have duration less than six months,, and 20 (28%) have a six months or more.

Conclusions: Pyogenic granuloma emerges as a prevalent reactive lesion in the oral and maxillofacial domain. The diode laser demonstrates utility in oral and facial soft tissue surgery owing to its facile application, enhanced coagulation, avoidance of suturing, reduced swelling and pain, and its capacity for esthetically favorable outcomes, encompassing superior de-epithelialization, absence of bleeding, and improved repair. The roles of surgeons and pathologists are pivotal in diagnosing and treating pyogenic granuloma in oral and maxillofacial regions.

背景:化脓性肉芽肿(PG)是一种位于皮肤或皮下组织的增生迅速的良性血管性肿瘤,是口腔颌面部常见的反应性病变。本研究旨在探讨口腔颌面部化脓性肉芽肿的临床病理特征:72名参与者,包括24名男性(33%)和48名女性(67%),利用940纳米和980纳米二极管激光对口腔颌面部的化脓性肉芽肿进行了手术消融。所有标本均采用标准的组织处理程序,随后切取厚度为 5 微米的石蜡包埋块进行 H & E 染色。对所有切片进行光学显微镜检查以确诊:所有病例均接受了化脓性肉芽肿外科激光消融术,其中 53 人(74%)年龄在 30 岁或以下,19 人(26%)年龄在 30 岁或以上,52 人(72%)病程少于 6 个月,20 人(28%)病程在 6 个月或以上:结论:化脓性肉芽肿是口腔颌面部常见的反应性病变。二极管激光器在口腔和面部软组织手术中表现出实用性,因为它应用简便、凝固效果好、无需缝合、减少肿胀和疼痛,而且能产生良好的美观效果,包括出色的去表皮化效果、无出血和改善修复效果。外科医生和病理学家在诊断和治疗口腔颌面部化脓性肉芽肿方面发挥着关键作用。
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Minerva dental and oral science
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