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Commentary: Expanding the vision of Registered Reports for qualitative mental health research: A response and extension to ‘Misaligned incentives in mental health research – the case for Registered Reports’, Baldwin (2023) 评论:扩展定性心理健康研究注册报告的视野:对《心理健康研究中错位的激励机制--注册报告的案例》的回应和延伸,Baldwin (2023)。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-18 DOI: 10.1111/jcpp.14039
Ola Demkowicz, Jo Hickman Dunne

There is a growing exploration of how Registered Reports can benefit individual researchers and wider research fields as part of a wider shift towards open research principles and practices. In ‘Misaligned incentives in mental health research – the case for Registered Reports’, Baldwin examines this in the context of mental health research, arguing that Registered Reports (RRs) can be a valuable solution to misaligned incentive structures in the field. However, this original piece was generally inclined towards how such incentives and the use of RRs can play out in the context of quantitative research. Such reflection is valuable, but to examine the case for RRs in mental health research as a field, we must also explore such practices within the context of qualitative research. In this commentary, we therefore expand and reframe this discussion to make the case for RRs in qualitative mental health research. We explore the place for qualitative research in the mental health research field and examine possibilities for how RRs fit within principles and practices in such methods. We discuss the various benefits and challenges of RRs in qualitative research, reflecting on our experiences as authors and reviewers of qualitative RRs and exploring how research infrastructure can facilitate engagement with this publishing approach.

作为向开放式研究原则和实践的广泛转变的一部分,人们越来越多地探索注册报告如何使研究人员个人和更广泛的研究领域受益。在《心理健康研究中的激励机制错位--注册报告的案例》一文中,鲍德温以心理健康研究为背景,探讨了这一问题,认为注册报告 (RR) 可以成为解决该领域激励机制错位问题的重要方法。不过,这篇原创文章总体上倾向于在定量研究中如何使用这种激励机制和注册报告。这种反思是有价值的,但要考察心理健康研究作为一个领域的 RRs 案例,我们还必须在定性研究的背景下探讨这种做法。因此,在本评论中,我们将扩展和重构这一讨论,为心理健康定性研究中的 RRs 提供依据。我们探讨了定性研究在心理健康研究领域的地位,并研究了 RR 如何与此类方法的原则和实践相适应的可能性。我们讨论了定性研究中 RRs 的各种益处和挑战,反思了我们作为定性 RRs 作者和审稿人的经验,并探讨了研究基础设施如何促进这种出版方法。
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引用次数: 0
Early relational origins of Theory of Mind: A two-study replication 心智理论的早期关系起源:两项研究的重复。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-18 DOI: 10.1111/jcpp.14029
Grazyna Kochanska, Lilly Bendel-Stenzel, Danming An, Neevetha Sivagurunathan

Background

Research implies early relational factors – parental appropriate mind-mindedness (MM) and mutually responsive orientation (MRO) – as antecedents of children's Theory of Mind (ToM), yet the longitudinal path is unclear. Furthermore, little is known about the process in father–child relationships. In two studies of community families in a Midwestern state in United States, we tested a path from parental appropriate MM in infancy to parent–child MRO in toddlerhood to children's ToM at preschool age in mother– and father–child relationships, using comparable observational measures at parallel ages.

Methods

In Children and Parents Study (CAPS) of children born in 2017 and 2018, we collected data at 8 months (N = 200, 96 girls), 38 months, age 3 (N = 175, 86 girls), and 52 months, age 4.5 (N = 177, 86 girls). In Family Study (FS) of children born mostly in 2001, we collected data at 7 months (N = 102, 51 girls), 38 months, age 3 (N = 100, 50 girls), and 52 months, age 4.5 (N = 99, 49 girls). Parental MM (verbal comments aligned with the infant's psychological state) was observed in infancy, MRO (parent and child responsiveness to each other and shared positive affect) at age 3, and ToM (false belief tasks) at age 4.5.

Results

The findings supported the proposed indirect effects of parents' MM on children's ToM, mediated by MRO, for fathers and children in both studies, and for mothers and children, in CAPS. In FS, mothers' MM predicted MRO and ToM, but there was no mediation.

Conclusions

This investigation, testing a path from MM to MRO to ToM in both mother– and father–child relationships in two longitudinal studies, adds to the literature that has described relations among those constructs but rarely integrated those in one model.

背景:研究表明,早期关系因素--父母适当的心智(MM)和相互回应取向(MRO)--是儿童心智理论(ToM)的前因,但其纵向发展路径尚不清楚。此外,人们对父子关系中的这一过程也知之甚少。在对美国中西部一个州的社区家庭进行的两项研究中,我们使用平行年龄段的可比观察指标,检验了从婴儿期父母适当的MM到学步期亲子MRO再到学龄前儿童心智理论在母子关系和父子关系中的发展路径:在2017年和2018年出生的儿童和家长研究(CAPS)中,我们收集了8个月(N = 200,96名女孩)、38个月,3岁(N = 175,86名女孩)和52个月,4.5岁(N = 177,86名女孩)时的数据。在主要针对 2001 年出生儿童的家庭研究(FS)中,我们收集了 7 个月(102 人,51 个女孩)、38 个月(3 岁)(100 人,50 个女孩)和 52 个月(4.5 岁)(99 人,49 个女孩)时的数据。在婴儿期观察了父母的MM(与婴儿心理状态一致的口头评论),在3岁时观察了MRO(父母和孩子对彼此的反应和共同的积极情感),在4.5岁时观察了ToM(错误信念任务):研究结果表明,在两项研究中,父母的 "MM "对父亲和儿童的 "ToM "都有间接影响,而在 "CAPS "中,父母的 "MM "对母亲和儿童的 "ToM "也有间接影响。在 FS 中,母亲的 MM 预测了 MRO 和 ToM,但没有中介作用:这项调查在两项纵向研究中测试了母亲和父亲与子女关系中从MM到MRO再到ToM的路径,为描述了这些建构之间关系但很少将其整合到一个模型中的文献增添了新的内容。
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引用次数: 0
Practitioner Review: Continuity of mental health care from childhood to adulthood for youths with ADHD – who, how and when? 从业者评论:患有多动症的青少年从童年到成年期间心理健康护理的连续性--谁、如何、何时?
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-16 DOI: 10.1111/jcpp.14036
Nicoletta Adamo, Swaran P. Singh, Sven Bölte, David Coghill, Jeffrey H. Newcorn, Valeria Parlatini, Diane Purper-Ouakil, Juliane Rausch, Luis Rohde, Paramala Santosh, Tobias Banaschewski, Jan K. Buitelaar

Many youths with attention-deficit/hyperactivity disorder (ADHD) experience significant long-term impairment and may develop concurrent mental and somatic health difficulties as adults. This is associated with burden and costs for the individual and society which could be prevented through continued support in youth. Yet, only few young people transition to adult mental health services for ongoing care in different countries worldwide. We provide an overview on current transition practices, highlighting the gaps in knowledge and the barriers to effective service transitioning, while considering the large geographical variation in available guidelines and service provision. For ease of use, this review is organized in a question-and-answer format covering different aspects of the transition process and considering both service users' and clinicians' perspectives. Consensus is needed to identify those that require continued care, the optimal timing to arrange transition, and the most suitable services. Finally, we discuss cost-effectiveness of transition practices, consider examples of best practice, and propose recommendations on how to improve transitional care, including the importance of service users' input into transition planning.

许多患有注意力缺陷/多动障碍(ADHD)的青少年在成年后会出现严重的长期障碍,并可能同时出现精神和躯体健康问题。这对个人和社会都会造成负担和成本,而在青少年时期通过持续的支持是可以避免的。然而,在世界各国,只有少数青少年过渡到成人精神健康服务机构接受持续治疗。我们概述了当前的过渡实践,强调了知识方面的差距以及有效服务过渡的障碍,同时考虑到现有指南和服务提供方面的巨大地域差异。为便于使用,本综述以问答形式组织,涵盖了过渡过程的不同方面,并考虑了服务使用者和临床医生的观点。我们需要达成共识,以确定哪些患者需要继续护理、安排过渡的最佳时机以及最合适的服务。最后,我们讨论了过渡做法的成本效益,考虑了最佳做法的范例,并就如何改善过渡护理提出了建议,包括服务使用者对过渡规划提出意见的重要性。
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引用次数: 0
Maternal disapproval of friends in response to child conduct problems damages the peer status of pre- and early adolescents 母亲因孩子的行为问题而不认可朋友,会损害学龄前和学龄初期青少年的同伴地位。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-14 DOI: 10.1111/jcpp.14043
Goda Kaniušonytė, Brett Laursen

Background

Herein, we consider the hypothesis that mothers harm peer relations when they respond to child conduct problems by expressing disapproval of friends, which exacerbates the behavior problems they were presumably attempting to deter.

Methods

A community sample of Lithuanian adolescents (292 boys and 270 girls, aged 9–14 years) completed surveys three times during an academic year. Classmate nominations indexed peer status (acceptance and rejection), self-reports described perceived maternal disapproval of friends, and peer nominations and self-reports separately gauged conduct problems.

Results

Over the course of a school year: (a) conduct problems were associated with subsequent increases in perceived maternal friend disapproval; (b) perceived maternal friend disapproval was associated with subsequent decreases in peer status; and (c) low peer status was associated with subsequent increases in conduct problems. Full longitudinal, random-intercept cross-lagged panel mediation models confirmed that mothers who disapproved of friends were sources of peer difficulties that culminated in conduct problems and intermediaries whose response to child conduct problems damaged peer relations. Findings were stronger for peer rejection than for peer acceptance, suggesting that peers actively dislike those with mothers who intervene in peer relationships.

Conclusions

Maternal disapproval of friends in response to child conduct problems damages the child's standing among peers, which then exacerbates behavior problems. This consequential cascade underscores the need for parent education about the potential deleterious consequences of well-intentioned interference in peer relations. Practitioners should be prepared to offer constructive, alternative solutions when youth present behavior problems.

背景:在此,我们提出了这样一个假设:当母亲对孩子的行为问题做出反应时,她们会对朋友表示不赞同,这就会损害同伴关系,从而加剧她们试图阻止的行为问题:立陶宛青少年(292 名男孩和 270 名女孩,年龄在 9-14 岁之间)在一学年内完成了三次社区抽样调查。同学提名反映了同伴的地位(接受和拒绝),自我报告描述了母亲对朋友的不认可,同伴提名和自我报告分别反映了行为问题:在一学年中:(a)行为问题与母亲对朋友的不认同感随之增加有关;(b)母亲对朋友的不认同感与同伴地位随之降低有关;(c)同伴地位低与行为问题随之增加有关。完整的纵向随机截距交叉滞后面板中介模型证实,不认可朋友的母亲是导致行为问题的同伴困难的根源,也是对儿童行为问题做出反应的破坏同伴关系的中介。对同伴拒绝的研究结果比对同伴接受的研究结果更强烈,这表明同伴主动不喜欢母亲干预同伴关系的人:结论:母亲因孩子的行为问题而不认可朋友,会损害孩子在同伴中的地位,进而加剧行为问题。这种一连串的后果突出表明,有必要对家长进行教育,让他们认识到善意干预同伴关系可能带来的有害后果。当青少年出现行为问题时,从业人员应做好准备,提供建设性的替代解决方案。
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引用次数: 0
Editorial Perspective: Healthy body—Healthy mind? Does exercise benefit people with attention-deficit/hyperactivity disorder? 编辑视角:健康的身体-健康的心灵?运动是否有益于注意力缺陷/多动障碍患者?
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-07 DOI: 10.1111/jcpp.14042
Shu-Shih Hsieh

Attention-deficit/hyperactivity disorder (ADHD) stands out as one of the most prevalent neurodevelopmental disorders, significantly affecting daily functioning. However, finding a sustainable treatment strategy for ADHD remains a challenge. In this context, exercise emerges as a highly accessible behavioural intervention with lasting effects on ADHD. Historically, exercise has proven effective in inducing functional and structural adaptations in the brains of neurotypical populations, leading to improved cognition. Scientists working with individuals with ADHD have adapted approaches from research on neurotypical populations to understand the effects of exercise on reducing ADHD-related symptoms. To advance this research area further and enhance the therapeutic potential of exercise for managing ADHD symptoms, this editorial perspective offers the following recommendations:

注意力缺陷/多动障碍(ADHD)是最普遍的神经发育障碍之一,严重影响日常功能。然而,寻找一种可持续的多动症治疗策略仍是一项挑战。在这种情况下,运动就成为了一种非常容易获得并对多动症具有持久疗效的行为干预措施。历史证明,运动能有效地诱导神经畸形人群大脑的功能和结构调整,从而改善认知能力。研究多动症患者的科学家们采用了神经畸形人群的研究方法,以了解运动对减轻多动症相关症状的效果。为了进一步推动这一研究领域的发展,提高运动对控制多动症症状的治疗潜力,本社论提出以下建议:需要开展更多研究,以更好地了解运动干预多动症的神经标记,以及多动症相关神经机制变化与行为和认知症状改变之间的相互关系。研究人员在制定针对多动症的运动计划时,应考虑使用者的观点,并将社会支持活动纳入其中;研究人员应利用高质量、设计良好的临床试验,将运动作为一种独立的治疗方法进行评估。
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引用次数: 0
Reciprocal relations between dimensions of attention-deficit/hyperactivity and anxiety disorders from preschool age to adolescence: sex differences in a birth cohort sample 从学龄前到青春期,注意力缺陷/多动症与焦虑症之间的相互关系:出生队列样本中的性别差异。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-04 DOI: 10.1111/jcpp.14038
Mojtaba Habibi Asgarabad, Silje Steinsbekk, Cynthia M. Hartung, Lars Wichstrøm

Background

Symptoms of anxiety and attention-deficit/hyperactivity disorder (ADHD) are prospectively related from childhood to adolescence. However, whether the two dimensions of ADHD—inattention and hyperactivity-impulsivity—are differentially related to anxiety and whether there are developmental and sex/gender differences in these relations are unknown.

Methods

Two birth cohorts of Norwegian children were assessed biennially from ages 4 to 16 (N = 1,077; 49% girls) with diagnostic parent interviews used to assess symptoms of anxiety and ADHD. Data were analyzed using a random intercept cross-lagged panel model, adjusting for all unobserved time-invariant confounding effects.

Results

In girls, increased inattention, but not hyperactivity-impulsivity, predicted increased anxiety 2 years later across all time-points and increased anxiety at ages 12 and 14 predicted increased inattention but not hyperactivity-impulsivity. In boys, increased hyperactivity-impulsivity at ages 6 and 8, but not increased inattention, predicted increased anxiety 2 years later, whereas increased anxiety did not predict increased inattention or hyperactivity-impulsivity.

Conclusions

The two ADHD dimensions were differentially related to anxiety, and the relations were sex-specific. In girls, inattention may be involved in the development of anxiety throughout childhood and adolescence and anxiety may contribute to girls developing more inattention beginning in early adolescence. In boys, hyperactivity-impulsivity may be involved in the development of anxiety during the early school years. Effective treatment of inattention symptoms in girls may reduce anxiety risk at all time-points, while addressing anxiety may decrease inattention during adolescence. Similarly, treating hyperactivity-impulsivity may reduce anxiety risk in boys during late childhood (at ages 8–10).

背景:焦虑症状和注意力缺陷/多动障碍(ADHD)从童年到青春期都有相关性。然而,注意力缺陷多动障碍(ADHD)的两个方面--注意力缺陷和多动冲动--是否与焦虑有不同的关系,以及在这些关系中是否存在发育和性别差异,目前尚不清楚:每两年对两批出生的挪威儿童(人数=1,077;49%为女孩)的4至16岁期间进行一次评估,并通过诊断性家长访谈来评估焦虑症和多动症的症状。数据采用随机截距交叉滞后面板模型进行分析,并对所有未观察到的时间不变混杂效应进行了调整:在所有时间点上,女孩注意力不集中程度的增加能预测 2 年后焦虑程度的增加,但不能预测多动-冲动程度的增加;12 岁和 14 岁时焦虑程度的增加能预测注意力不集中程度的增加,但不能预测多动-冲动程度的增加。在男孩中,6 岁和 8 岁时多动-冲动的增加(而不是注意力不集中的增加)可预测 2 年后焦虑的增加,而焦虑的增加并不能预测注意力不集中或多动-冲动的增加:结论:注意力缺陷多动障碍的两个方面与焦虑有不同的关系,而且这种关系具有性别特异性。在女孩中,注意力不集中可能与整个童年和青春期的焦虑发展有关,而焦虑可能导致女孩从青春期早期开始注意力更加不集中。在男孩中,多动-冲动可能与学龄初期焦虑症的发展有关。有效治疗女孩的注意力不集中症状可能会降低所有时间点的焦虑风险,而解决焦虑问题可能会减少青春期注意力不集中的情况。同样,治疗多动-冲动症可能会降低男孩在童年晚期(8-10 岁)的焦虑风险。
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引用次数: 0
Commentary: Optimism for the future of research on disruptive behaviors – an appreciation of good science as illustrated by Nobakht, Steinsbekk & Wichstrom (2023) 评论:对破坏性行为研究的未来持乐观态度--Nobakht、Steinsbekk 和 Wichstrom(2023 年)对良好科学的赞赏。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-07-04 DOI: 10.1111/jcpp.14041
Jeffrey D. Burke

This paper by Nobakht, Steinsbekk & Wichstrom (2023) is a model of good science in the study of oppositional defiant disorder and conduct disorder. Their approach illustrates a thoughtful research design, statistical modeling sufficient to empirically evaluate developmental processes, and a full consideration of the theoretical implications of their work. This contrasts with a broad history of research on ODD and CD that far too often has only reified biased assumptions about these phenomena rather than rigorously scrutinizing them. Their demonstration of a unidirectional developmental flow of influence from ODD to interparental aggression, and thence to CD highlights a set of complicated developmental processes involving these disorders and their environment. It expands on evidence of the toll that ODD exerts on parents and provides guidance for more specific intervention. Standards in developmental psychopathology research should include testing bidirectional processes and employing designs that could falsify rather than reify existing beliefs. Examining key mechanisms in such processes will more rapidly generate improvements in assessment and treatment.

Nobakht、Steinsbekk 和 Wichstrom(2023 年)的这篇论文是研究对立违抗障碍和行为障碍的优秀科学典范。他们的研究方法体现了深思熟虑的研究设计、足以对发展过程进行实证评估的统计建模,以及对其工作的理论意义的充分考虑。这与有关逆反障碍和行为障碍的广泛研究历史形成了鲜明对比,后者往往只是重申了对这些现象的有偏见的假设,而不是对其进行严格审查。他们证明了从 ODD 到父母间攻击,再到 CD 的单向发展影响流,强调了涉及这些障碍及其环境的一系列复杂的发展过程。它进一步证实了 ODD 对父母造成的伤害,并为更具体的干预措施提供了指导。发育性精神病理学研究的标准应包括测试双向过程,并采用可证实而非证实现有观点的设计。对这些过程中的关键机制进行研究,可以更快地改进评估和治疗。
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引用次数: 0
Feeling anxious and being engaged in a warming world: climate anxiety and adolescents' pro-environmental behavior 在气候变暖的世界中感到焦虑并参与其中:气候焦虑与青少年的环保行为
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-28 DOI: 10.1111/jcpp.14035
Andrik Becht, Jenna Spitzer, Stathis Grapsas, Judith van de Wetering, Astrid Poorthuis, Anouk Smeekes, Sander Thomaes

Background

Climate anxiety is increasingly prevalent among adolescents worldwide. Are climate-anxious adolescents prone to engage in pro-environmental behavior? Or might the association between climate anxiety and pro-environmental be curvilinear, such that high levels of climate anxiety become ‘paralyzing’? And do these associations depend on whether adolescents believe that, with effort, the worst impacts of climate change can still be prevented?

Methods

We addressed these questions in three studies (two preregistered; combined N = 2,211), conducted across two countries. We used cross-sectional and longitudinal methods, and various measures of climate anxiety and pro-environmental behavior. We performed Bayesian regression analyses comparing two models that tested competing hypotheses. The first model included a linear effect of climate anxiety on pro-environmental behavior, and the second model included both a linear and a curvilinear (i.e. inverted U-shaped) effect of climate anxiety on pro-environmental behavior. Next, we added environmental efficacy to the best fitting model and explored its moderating effects.

Results

Adolescents reported low-to-moderate levels of climate anxiety. Across the board, we found evidence for a small, positive, and mostly linear (rather than curvilinear) association between climate anxiety and pro-environmental behavior. While Study 1 supported a curvilinear association (Bayes Factor (BF) = 18.87), Studies 2 and 3 mostly supported a linear model (BFs range 6.86–12.71), except for weak support (BF = 1.62) for a curvilinear association between climate anxiety symptoms and public sphere pro-environmental behavior. Adolescents' environmental efficacy moderated this link for public sphere (e.g. activism), but not private sphere (e.g. recycling), pro-environmental behavior.

Conclusions

Climate-anxious adolescents are prone to engage in pro-environmental behavior. We found limited evidence for ‘eco-paralysis’ (i.e. a passive state of pro-environmental behavioral stasis) at high levels of climate anxiety. Our results are consistent with the possibility that supporting adolescents' environmental efficacy will help climate-anxious adolescents engage in public sphere pro-environmental behavior.

背景气候焦虑在全球青少年中越来越普遍。对气候感到焦虑的青少年是否容易采取亲环境行为?或者,气候焦虑与亲环境行为之间的关系可能是曲线关系,从而使高度的气候焦虑变得 "麻痹"?这些关联是否取决于青少年是否相信,只要努力,气候变化的最坏影响还是可以预防的? 方法我们在两个国家进行的三项研究(两项是预先登记的;总人数 = 2,211)中探讨了这些问题。我们采用了横截面和纵向方法,以及各种气候焦虑和亲环境行为的测量方法。我们对两个模型进行了贝叶斯回归分析比较,以检验相互竞争的假设。第一个模型包括气候焦虑对亲环境行为的线性影响,第二个模型包括气候焦虑对亲环境行为的线性和曲线(即倒 U 型)影响。接下来,我们在最佳拟合模型中加入了环境效能,并探讨了其调节作用。在所有研究中,我们都发现了气候焦虑与亲环境行为之间存在微小的、积极的、多为线性关系(而非曲线关系)的证据。研究 1 支持曲线关系(贝叶斯因子 (Bayes Factor) = 18.87),而研究 2 和研究 3 大多支持线性模型(贝叶斯因子范围为 6.86-12.71),只有气候焦虑症状与公共领域亲环境行为之间的曲线关系得到微弱支持(贝叶斯因子 = 1.62)。青少年的环境效能调节了公共领域(如行动主义)而非私人领域(如回收利用)亲环境行为之间的联系。我们发现,在高度气候焦虑的情况下,"生态麻痹"(即亲环境行为停滞的被动状态)的证据有限。我们的研究结果表明,支持青少年的环境效能将有助于气候焦虑青少年在公共领域参与亲环境行为。
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引用次数: 0
Editorial Perspective: Extending IPDMA methodology to drive treatment personalisation in child mental health 编辑视角:扩展 IPDMA 方法,推动儿童精神健康治疗的个性化
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-28 DOI: 10.1111/jcpp.14025
Lizél-Antoinette Bertie, Maaike H. Nauta, Bas Kooiman, Wenting Chen, Jennifer L. Hudson

To improve outcomes for youth who do not respond optimally to existing treatments, we need to identify robust predictors, moderators, and mediators that are ideal targets for personalisation in mental health care. We propose a solution to leverage the Individual Patient Data Meta-analysis (IPDMA) approach to allow broader access to individual-level data while maintaining methodological rigour. Such a resource has the potential to answer questions that are unable to be addressed by single studies, reduce researcher burden, and enable the application of newer statistical techniques, all to provide data-driven strategies for clinical decision-making. Using childhood anxiety as the worked example, the editorial perspective outlines the rationale for leveraging IPDMA methodology to build a data repository, the Platform for Anxiety Disorder Data in Youth. We also include recommendations to address the methods and challenges inherent in this endeavour.

为了改善那些对现有治疗方法反应不佳的青少年的治疗效果,我们需要确定稳健的预测因子、调节因子和中介因子,它们是心理健康护理个性化的理想目标。我们提出了一种利用个体患者数据元分析 (IPDMA) 方法的解决方案,以便在保持方法严谨性的同时更广泛地获取个体层面的数据。这种资源有可能回答单项研究无法回答的问题,减轻研究人员的负担,并使更新的统计技术得以应用,从而为临床决策提供以数据为导向的策略。本社论以儿童焦虑症为例,概述了利用 IPDMA 方法建立数据存储库--青少年焦虑症数据平台--的基本原理。我们还提出了一些建议,以解决这项工作中固有的方法和挑战。
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引用次数: 0
Executive functioning and treatment outcome among adolescents undergoing cognitive-behavioral therapy for binge-eating disorder 接受认知行为疗法治疗暴饮暴食症的青少年的执行功能和治疗效果
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-28 DOI: 10.1111/jcpp.14031
Andrea B. Goldschmidt, Kwonho Jeong, Lan Yu, Amy H. Egbert, Ricarda Schmidt, Anja Hilbert

Background

Cognitive-behavioral therapy (CBT) is an evidence-supported treatment for adolescents with binge-eating disorder (BED). Executive dysfunctions, which are associated with binge eating and elevated body weight in youth, may undermine CBT outcomes by making it difficult for youth to engage with or adhere to treatment, including recalling and/or implementing intervention strategies in real-world contexts.

Methods

We assessed 73 adolescents [82.2% female; Mage = 15.0 ± 2.5 year; M baseline standardized body mass index (zBMI) = 1.9 ± 1.0 kg/m2] with BED at baseline, posttreatment, 6-, 12-, and 24-month follow-up. Linear mixed models examined the effects of baseline executive functioning (EF) on loss of control (LOC) eating and weight change following CBT. Linear and logistic regressions probed associations between EF, attendance, and attrition.

Results

More impulsive decision-making, as reflected in higher baseline scores on the Iowa Gambling Task, predicted better attendance (β = .07; p = .019) and more frequent LOC eating following treatment (β = .12; p = .017). Lower cognitive flexibility, as reflected in lower baseline T-scores on the Comprehensive Trail Making Test complex sequencing index, predicted higher zBMI following treatment (β = −.03; p = .003). Inhibition, concentration, attention, and parent-reported EF behavior symptoms were not associated with outcome, attendance, or attrition.

Conclusions

More impulsive decision-making and lower cognitive flexibility were associated with suboptimal response to CBT for BED, although findings should be interpreted with caution in light of the sample size and waitlist control design. Future research should examine whether strengthening EF could improve eating and weight outcomes among adolescents with BED who have lower pre-treatment EF.

背景认知行为疗法(CBT)是一种针对暴饮暴食症(BED)青少年的有证据支持的治疗方法。青少年的执行功能障碍与暴饮暴食和体重增加有关,它可能会使青少年难以参与或坚持治疗,包括在现实环境中回忆和/或实施干预策略,从而影响 CBT 的治疗效果。方法我们评估了 73 名青少年(82.2% 为女性;年龄 = 15.0 ± 2.5 岁;M 基线标准化体重指数 (zBMI) = 1.9 ± 1.0 kg/m2)在基线、治疗后、6 个月、12 个月和 24 个月随访时的暴饮暴食情况。线性混合模型检验了基线执行功能(EF)对失控饮食(LOC)和CBT后体重变化的影响。结果 爱荷华州赌博任务的基线分数越高,表明患者的决策冲动性越强,这预示着患者的出勤率越高(β = .07; p = .019),治疗后的失控饮食频率越高(β = .12; p = .017)。较低的认知灵活性(反映在较低的 "综合寻迹测验 "复杂排序指数基线 T 分数上)预示着治疗后较高的 zBMI(β = -.03;p = .003)。结论更冲动的决策和更低的认知灵活性与CBT治疗BED的次优反应有关,但考虑到样本量和候补对照设计,对研究结果的解释应谨慎。未来的研究应探讨加强EF是否能改善治疗前EF较低的BED青少年的饮食和体重结果。
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引用次数: 0
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Journal of Child Psychology and Psychiatry
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