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Editorial: No short-cuts – translating neurobiological knowledge to clinical practice requires moving away from stand-alone biomarkers to an integrative biopsychosocial approach 社论:没有捷径可走--将神经生物学知识转化为临床实践需要从独立的生物标志物转向综合的生物-心理-社会方法。
IF 7.6 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-15 DOI: 10.1111/jcpp.14001
Lucres Jansen

Although decades of research have shown the importance of neurobiological factors in the development of mental health problems in children and adolescents, the translation of this knowledge to use in clinical practice has proven difficult. One of the pitfalls is the false assumption that biological factors are so fundamental that they overrule all other factors and can be used as stand-alone biomarkers or tests for diagnostic purposes and treatment decisions. This assumption is false because all neurodevelopmental disorders result from complex interactions between biology and environment. Therefore, neurobiological assessments should never be used as a shortcut for diagnostic assessments that include the environment, including family, peers, and society at large. Instead, they should be integrated in the diagnostic process. This calls for empirically supported guidance on how to weigh information from neurobiological and psychosocial assessments in the diagnostic and treatment decision process.

尽管数十年的研究表明,神经生物学因素在儿童和青少年心理健康问题的发展过程中起着重要作用,但要将这些知识转化为临床实践中的应用却很困难。其中一个误区是,人们错误地认为生物因素是最基本的因素,以至于可以凌驾于所有其他因素之上,并可作为独立的生物标记或测试用于诊断目的和治疗决策。这种假设是错误的,因为所有的神经发育障碍都是由生物学和环境之间复杂的相互作用造成的。因此,神经生物学评估绝不能作为诊断评估的捷径,因为诊断评估应包括家庭、同伴和整个社会等环境。相反,应将其纳入诊断过程。这就要求在诊断和治疗决策过程中,就如何权衡来自神经生物学和社会心理评估的信息提供有经验支持的指导。
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引用次数: 0
Health, behavior, and social outcomes among offspring of parents with criminal convictions: a register-based study from Sweden 父母有犯罪前科的后代的健康、行为和社会结果:瑞典的一项登记研究。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-13 DOI: 10.1111/jcpp.14003
Aurora Järvinen, Paul Lichtenstein, Brian M. D'Onofrio, Seena Fazel, Ralf Kuja-Halkola, Antti Latvala

Background

There is currently insufficient understanding of the health and behavior of children whose parents engage in criminal behavior. We examined associations between parental criminal convictions and wide range of offspring health, behavioral, and social outcomes by age 18 in a large, national sample, aiming to get a comprehensive picture of the risks among children of offending parents.

Methods

We studied 1,013,385 individuals born in Sweden between 1987 and 1995, and their parents. Using data from several longitudinal nationwide registers, we investigated parental convictions and 85 offspring outcomes until the end of 2013, grouped into birth-related conditions, psychiatric and somatic disorders, accidents and injuries, mortality, school achievement, violent victimization, and criminality. Cox proportional hazards regression and logistic regression models were used to examine the associations. The role of genetic factors in intergenerational associations was studied in children-of-siblings analyses. We also examined the co-occurrence of multiple outcomes using Poisson regression.

Results

A total of 223,319 (22.0%) individuals had one parent convicted and 31,241 (3.1%) had both parents convicted during the first 18 years of their life. The strongest associations were found between parental convictions and offspring behavioral problems, substance use disorders, poor school achievement, violent victimization, and criminality, with an approximately 2 to 2.5-fold increased risk in children with one convicted parent and 3- to 4-fold increased risk in children with two convicted parents. The risks were particularly elevated among children of incarcerated parents with a history of violent convictions. The associations appeared to be at least partly explained by genetic influences. Parental convictions were also associated with an increased likelihood of experiencing multiple outcomes.

Conclusions

Our findings help to calibrate the risks of a wide range of adverse outcomes associated with parental convictions and may be used to guide prevention efforts and identify key areas for future research.

背景:目前,人们对父母有犯罪行为的儿童的健康和行为还缺乏足够的了解。我们在全国范围内抽取了大量样本,研究了父母的刑事定罪与 18 岁时后代的健康、行为和社会结果之间的关联,旨在全面了解父母犯罪的子女所面临的风险:我们对 1987 年至 1995 年间在瑞典出生的 1,013,385 人及其父母进行了研究。利用多个全国性纵向登记册中的数据,我们调查了父母的犯罪情况和截至 2013 年底的 85 个后代结果,这些结果分为出生相关情况、精神和躯体疾病、事故和伤害、死亡率、学业成绩、暴力伤害和犯罪情况。研究采用了考克斯比例危险回归和逻辑回归模型来检验这些关联。在同胞子女分析中研究了遗传因素在代际关联中的作用。我们还使用泊松回归法研究了多种结果的共同发生情况:共有 223,319 人(22.0%)的父母中有一人被定罪,31,241 人(3.1%)的父母在其出生后的前 18 年中均被定罪。研究发现,父母被判刑与后代的行为问题、药物使用障碍、学业成绩差、暴力受害和犯罪之间的关系最为密切,父母一方被判刑的儿童的风险大约增加 2 到 2.5 倍,父母双方被判刑的儿童的风险大约增加 3 到 4 倍。父母被监禁且有暴力犯罪史的儿童的风险尤其高。这些关联似乎至少部分是由遗传影响造成的。父母被定罪还与出现多种结果的可能性增加有关:我们的研究结果有助于校准与父母定罪相关的一系列不良后果的风险,并可用于指导预防工作和确定未来研究的关键领域。
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引用次数: 0
Positive and negative social media experiences and proximal risk for suicidal ideation in adolescents 青少年积极和消极的社交媒体经历与自杀倾向的近端风险。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-13 DOI: 10.1111/jcpp.13996
Jessica L. Hamilton, Maya Dalack, Simone Imani Boyd, Saskia Jorgensen, Melissa J. Dreier, Jas Sarna, David A. Brent

Background

Social media (SM) has received considerable attention as a potential risk factor for adolescent suicide. Few empirical studies, however, have examined adolescents' daily negative and positive experiences on SM and its proximal impacts on suicidal ideation (SI), particularly using intensive monitoring designs.

Method

Adolescents (N = 60; 14–17 years; 49% girls; 62% LGBTQ+) recruited using SM across the United States and participated in an 8-week intensive monitoring protocol. Ecological momentary assessment (three brief surveys per day) asked about negative and positive SM experiences and SI (passive and active). Multilevel modelling was used to evaluate the within-person relationships between daily SM experiences (e.g. individual fluctuations compared to a person's average) and SI, controlling for average levels of SM experiences, SM use screen time, and lifetime SI.

Results

Significant within-person effects of negative and positive SM experiences were associated with days when adolescents had SI. Specifically, on days when teens endorsed more frequent negative SM experiences than usual, they were more likely to report SI. However, more positive SM experiences than usual were associated with a lower likelihood of having SI. There were no significant effects of SM use (‘screen time’) on SI or on the reverse associations of SI on next-day SM experiences.

Conclusions

Results indicate that SM experiences may be dynamic and modifiable risk and protective factors for SI in adolescents, whereas there is no effect of SM screen time on SI. Our results highlight that targeting negative SM experiences and augmenting the positive experiences on SM may be critical targets to improve teens' mental health and prevent suicide, rather than focusing on limiting SM screen time.

背景:社交媒体(SM)作为青少年自杀的潜在风险因素受到了广泛关注。然而,很少有实证研究对青少年在社交媒体上的日常负面和正面经历及其对自杀意念(SI)的近端影响进行研究,尤其是采用强化监测设计的研究:青少年(N = 60;14-17 岁;49% 为女孩;62% 为 LGBTQ+)通过 SM 在美国各地招募,并参加了为期 8 周的强化监测方案。生态瞬间评估(每天三次简短调查)询问消极和积极的 SM 体验以及 SI(被动和主动)。多层次建模用于评估每日SM体验(例如,与个人平均水平相比的个人波动)和SI之间的人际关系,同时控制SM体验的平均水平、SM使用屏幕时间和终生SI:结果:青少年的消极和积极 SM 体验与 SI 日有显著的个人内部影响。具体来说,当青少年比平时更频繁地认可消极的SM经历时,他们更有可能报告SI。然而,比平时更积极的SM经历则与发生SI的可能性较低有关。SM使用("屏幕时间")对SI或SI对第二天SM经历的反向关联没有明显影响:结果表明,SM经历可能是青少年SI的动态和可改变的风险和保护因素,而SM屏幕时间对SI没有影响。我们的研究结果突出表明,针对青少年的消极SM体验和增加SM中的积极体验可能是改善青少年心理健康和预防自杀的关键目标,而不是专注于限制SM屏幕时间。
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引用次数: 0
‘I'm still su!c!dal when you're done with the paperwork’: an inductive framework thematic analysis of #camhs on TikTok 当你做完文书工作后,我仍然是你的朋友":对 TikTok 上 #camhs 的归纳框架主题分析。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-09 DOI: 10.1111/jcpp.14002
Molly Foster, Hannah Frith, Mary John

Background

Young people are sharing their experiences of Child and Adolescent Mental Health Services (CAMHS) in the United Kingdom on TikTok. Little is known about the content of these videos and their influence on young people's attitudes towards seeking professional mental health support.

Methods

This study explored how CAMHS is represented in a sample of 100 #camhs TikTok videos using participatory inductive framework thematic analysis.

Results

Four themes were developed alongside young people as co-researchers: (a) CAMHS can be frustrating and unhelpful, but sometimes life-saving, (b) Young people can feel their distress is invalidated by CAMHS, (c) CAMHS makes young people feel responsible for their distress, and (d) Young people may not feel CAMHS professionals are trustworthy. Video content described dismissive responses to expressions of suicidal ideation, professional knowledge being privileged over lived experience, and breaches of confidentiality. Some shared positive experiences of CAMHS helping to keep them safe.

Conclusions

Together, the themes reflect a representation of CAMHS as a service where adults are powerful and young people occupy a subjugated position. This may influence young people's professional help-seeking behaviour. Recommendations for clinical practice and future research are presented.

背景:年轻人在 TikTok 上分享他们在英国儿童和青少年心理健康服务(CAMHS)中的经历。人们对这些视频的内容及其对年轻人寻求专业心理健康支持的态度的影响知之甚少:本研究采用参与式归纳框架主题分析法,对 100 个 #camhs TikTok 视频样本中如何体现 CAMHS 进行了探讨:研究人员与作为共同研究者的年轻人一起提出了四个主题:(a) CAMHS 可能会让人感到沮丧和无助,但有时却能挽救生命;(b) 年轻人可能会觉得他们的痛苦被 CAMHS 无视;(c) CAMHS 会让年轻人觉得他们要为自己的痛苦负责;(d) 年轻人可能会觉得 CAMHS 的专业人员不值得信任。视频内容描述了对表达自杀意念的轻蔑反应、专业知识优于生活经验,以及违反保密规定的情况。一些青少年则分享了儿童及青少年保健服务机构帮助他们保护安全的积极经验:总之,这些主题反映出儿童及青少年心理健康服务是一种成年人强势而青少年处于从属地位的服务。这可能会影响青少年寻求专业帮助的行为。本文对临床实践和未来研究提出了建议。
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引用次数: 0
Practitioner Review: Assessment and treatment of body dysmorphic disorder in young people 从业者评论:青少年身体畸形障碍的评估和治疗。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-08 DOI: 10.1111/jcpp.13984
Georgina Krebs, Daniel Rautio, Lorena Fernández de la Cruz, Andrea S. Hartmann, Amita Jassi, Alexandra Martin, Argyris Stringaris, David Mataix-Cols

Body dysmorphic disorder (BDD) is a relatively common and highly impairing mental disorder that is strikingly underdiagnosed and undertreated in Child and Adolescent Mental Health Services (CAMHS). The only clinical guidelines for the management of BDD in youth were published nearly 20 years ago, when empirical knowledge was sparse. Fortunately, there has been a surge in research into BDD over the last 10 years, shedding important insights into the phenomenology, epidemiology, assessment and treatment of the disorder in young people. This review aimed to provide an overview of recent research developments of relevance to clinicians and healthcare policymakers. We summarise key findings regarding the epidemiology of BDD in youth, which indicate that the disorder usually develops during teenage years and affects approximately 2% of adolescents at any one point in time. We provide an overview of aetiological research, highlighting that BDD arises from an interplay between genetic and environmental influences. We then focus on screening and assessment strategies, arguing that these are crucial to promote detection and diagnosis of this under-recognised condition. Additionally, we summarise the recommended treatment approaches for BDD in youth, namely cognitive behaviour therapy with or without selective serotonin reuptake inhibitors. The review concludes by highlighting key knowledge gaps and priorities for future research including, but not limited to, better understanding aetiological factors, long-term consequences and treatment.

身体畸形障碍(BDD)是一种相对常见且极易造成伤害的精神障碍,在儿童及青少年心理健康服务机构(CAMHS)中的诊断率和治疗率都非常低。针对青少年 BDD 治疗的唯一临床指南发布于近 20 年前,当时的经验知识还很匮乏。幸运的是,在过去的 10 年中,对 BDD 的研究激增,对青少年 BDD 的现象学、流行病学、评估和治疗有了重要的认识。本综述旨在概述与临床医生和医疗决策者相关的最新研究进展。我们总结了有关青少年 BDD 流行病学的主要研究结果,这些结果表明,该障碍通常在青少年时期发病,在任何一个时间点都会影响大约 2% 的青少年。我们概述了病因学研究,强调 BDD 是遗传和环境影响相互作用的结果。然后,我们重点介绍筛查和评估策略,认为这些策略对于促进发现和诊断这种未被充分认识的疾病至关重要。此外,我们还总结了针对青少年 BDD 的推荐治疗方法,即认知行为疗法和或不使用选择性血清素再摄取抑制剂。综述最后强调了主要的知识差距和未来研究的重点,包括但不限于更好地了解致病因素、长期后果和治疗方法。
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引用次数: 0
Examining variability in Naturalistic Developmental Behavioral Intervention strategy use in caregivers of children with autism spectrum disorders. 研究自闭症谱系障碍儿童照顾者在使用自然发展行为干预策略方面的差异。
IF 7.6 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-08 DOI: 10.1111/jcpp.13994
Hallie Brown, Deanna Swain, Hye Won Kim, Sally Rogers, Annette Estes, Connie Kasari, Catherine Lord, So Hyun Kim

Background: Naturalistic Developmental Behavioral Interventions (NDBIs) for young children with autism spectrum disorder commonly involve caregiver-mediated approaches. However, to date, there is limited research on how caregivers' skills change, and, in turn, impact child outcomes.

Methods: We evaluated the NDBI strategy use of 191 caregivers prior to participation in NDBIs (or control groups) across multiple randomized controlled trials, using the Measure of NDBI Strategy Implementation, Caregiver Change (MONSI-CC). Clustering analyses were used to examine caregiver variability in NDBI strategy use at intervention entry. Generalized Linear Mixed Models were used to examine changes in caregiver strategy use over the course of intervention and its impact on changes in children's social communication.

Results: Using clustering analysis, we found that caregivers' baseline skills fit four profiles: limited, emerging, variable, and consistent/high, with few demographic factors distinguishing these groups. Caregivers starting with limited or emerging skills improved in their strategy use with intervention. Caregivers starting with more skills (consistent/high or variable) maintained higher skills over intervention. Children of caregivers in these groups who received target NDBIs improved in their social communication skills.

Conclusions: Results suggested that caregiver skills improve through participation in NDBIs and may directly contribute to their children's outcomes, although more research on mediating factors is needed. Individualized approaches for caregivers and their children starting with differing skill profiles at intervention entry may be warranted.

背景:针对自闭症谱系障碍幼儿的自然发展行为干预(NDBI)通常采用以照顾者为媒介的方法。然而,迄今为止,关于照顾者的技能如何发生变化并进而影响儿童结果的研究十分有限:我们在多个随机对照试验中,使用 "NDBI 策略实施、照顾者变化测量法"(MONSI-CC)评估了 191 名照顾者在参与 NDBI(或对照组)之前的 NDBI 策略使用情况。聚类分析用于考察护理者在干预开始时使用 NDBI 策略的差异性。使用广义线性混合模型研究了干预过程中照料者策略使用的变化及其对儿童社会交流变化的影响:通过聚类分析,我们发现看护者的基线技能符合四种情况:有限的、新兴的、可变的和稳定/高的,几乎没有人口统计学因素可以区分这些组别。起初技能有限或刚刚开始掌握技能的护理人员在接受干预后使用策略的能力有所提高。开始时技能较高(稳定/高或可变)的照顾者在干预期间保持了较高的技能。在这些组别中,接受目标 NDBIs 的照护者的子女在社交沟通技能方面有所提高:结果表明,照顾者的技能通过参与 NDBIs 得到提高,并可能直接促进其子女的成果,尽管还需要对中介因素进行更多研究。在干预开始时,照顾者及其子女的技能状况各不相同,因此可能需要采取个性化的方法。
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引用次数: 0
Life course predictors of child emotional distress during the COVID-19 pandemic: Findings from a prospective intergenerational cohort study COVID-19大流行期间儿童情绪困扰的生命历程预测因素:一项前瞻性代际队列研究的结果。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-07 DOI: 10.1111/jcpp.13995
Primrose Letcher, Christopher J. Greenwood, Jacqui A. Macdonald, Joanne Ryan, Meredith O'Connor, Kimberly C. Thomson, Ebony J. Biden, Felicity Painter, Catherine M. Olsson, Ben Edwards, Jennifer McIntosh, Elizabeth A. Spry, Delyse Hutchinson, Joyce Cleary, Tim Slade, Craig A. Olsson

Background

We examine precursors of child emotional distress during the COVID-19 pandemic in a prospective intergenerational Australian cohort study.

Methods

Parents (N = 549, 60% mothers) of 934 1–9-year-old children completed a COVID-19 specific module in 2020 and/or 2021. Decades prior, a broad range of individual, relational and contextual factors were assessed during parents' own childhood, adolescence and young adulthood (7–8 to 27–28 years old; 1990–2010) and again when their children were 1 year old (2012–2019).

Results

After controlling for pre-pandemic socio-emotional behaviour problems, COVID-19 child emotional distress was associated with a range of pre-pandemic parental life course factors including internalising difficulties, lower conscientiousness, social skills problems, poorer relational health and lower trust and tolerance. Additionally, in the postpartum period, pre-pandemic parental internalising difficulties, lower parental warmth, lower cooperation and fewer behavioural competencies predicted child COVID-19 emotional distress.

Conclusions

Findings highlight the importance of taking a larger, intergenerational perspective to better equip young populations for future adversities. This involves not only investing in child, adolescent, and young adult emotional and relational health, but also in parents raising young families.

背景:我们在澳大利亚前瞻性代际队列研究中考察了 COVID-19 大流行期间儿童情绪困扰的前兆:我们在一项澳大利亚前瞻性代际队列研究中考察了COVID-19大流行期间儿童情绪困扰的前兆:934名1-9岁儿童的父母(N = 549,60%为母亲)在2020年和/或2021年完成了COVID-19特定模块。在此之前的几十年里,在父母自己的童年、少年和青年时期(7-8 岁至 27-28 岁;1990-2010 年),以及在他们的孩子 1 岁时(2012-2019 年),对广泛的个人、关系和环境因素进行了评估:在控制了大流行前的社会情绪行为问题后,COVID-19 儿童情绪困扰与大流行前父母的一系列生命历程因素有关,包括内化困难、较低的自觉性、社交技能问题、较差的关系健康以及较低的信任和容忍度。此外,在产后阶段,大流行前父母的内化困难、父母温暖程度较低、合作程度较低以及行为能力较低等因素也预示着儿童的 COVID-19 情绪困扰:研究结果凸显了从更广阔的、跨代的视角来更好地帮助年轻人应对未来逆境的重要性。这不仅包括投资于儿童、青少年和年轻成人的情感和关系健康,还包括投资于抚养年轻家庭的父母。
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引用次数: 0
Shorter night-time sleep duration and later sleep timing from infancy to adolescence 从婴儿期到青春期,夜间睡眠时间缩短,睡眠时间推迟
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-06 DOI: 10.1111/jcpp.14004
Ifigeneia Manitsa, Alice M. Gregory, Matthew R. Broome, Andrew P. Bagshaw, Steven Marwaha, Isabel Morales-Muñoz

Background

Here, we (a) examined the trajectories of night-time sleep duration, bedtime and midpoint of night-time sleep (MPS) from infancy to adolescence, and (b) explored perinatal risk factors for persistent poor sleep health.

Methods

This study used data from 12,962 participants in the Avon Longitudinal Study of Parents and Children (ALSPAC). Parent or self-reported night-time sleep duration, bedtime and wake-up time were collected from questionnaires at 6, 18 and 30 months, and at 3.5, 4–5, 5–6, 6–7, 9, 11 and 15–16 years. Child's sex, birth weight, gestational age, health and temperament, together with mother's family adversity index (FAI), age at birth, prenatal socioeconomic status and postnatal anxiety and depression, were included as risk factors for persistent poor sleep health. Latent class growth analyses were applied first to detect trajectories of night-time sleep duration, bedtime and MPS, and we then applied logistic regressions for the longitudinal associations between risk factors and persistent poor sleep health domains.

Results

We obtained four trajectories for each of the three sleep domains. In particular, we identified a trajectory characterized by persistent shorter sleep, a trajectory of persistent later bedtime and a trajectory of persistent later MPS. Two risk factors were associated with the three poor sleep health domains: higher FAI with increased risk of persistent shorter sleep (OR = 1.20, 95% CI = 1.11–1.30, p < .001), persistent later bedtime (OR = 1.28, 95% CI = 1.19–1.39, p < .001) and persistent later MPS (OR = 1.30, 95% CI = 1.22–1.38, p < .001); and higher maternal socioeconomic status with reduced risk of persistent shorter sleep (OR = 0.99, 95% CI = 0.98–1.00, p = .048), persistent later bedtime (OR = 0.98, 95% CI = 0.97–0.99, p < .001) and persistent later MPS (OR = 0.99, 95% CI = 0.98–0.99, p < .001).

Conclusions

We detected trajectories of persistent poor sleep health (i.e. shorter sleep duration, later bedtime and later MPS) from infancy to adolescence, and specific perinatal risk factors linked to persistent poor sleep health domains.

背景在此,我们(a)研究了从婴儿期到青春期的夜间睡眠时间、就寝时间和夜间睡眠中点(MPS)的变化轨迹;(b)探讨了导致睡眠健康状况持续不佳的围产期风险因素。方法本研究使用了雅芳父母与子女纵向研究(ALSPAC)12962 名参与者的数据。在 6 个月、18 个月和 30 个月以及 3.5 岁、4-5 岁、5-6 岁、6-7 岁、9 岁、11 岁和 15-16 岁时,通过问卷调查收集了家长或自我报告的夜间睡眠时间、就寝时间和起床时间。儿童的性别、出生体重、胎龄、健康状况和性情,以及母亲的家庭逆境指数(FAI)、出生年龄、产前社会经济状况、产后焦虑和抑郁,都被列为导致儿童睡眠健康状况持续不良的风险因素。我们首先应用潜类增长分析来检测夜间睡眠时间、就寝时间和MPS的轨迹,然后应用Logistic回归分析风险因素与持续不良睡眠健康领域之间的纵向关联。特别是,我们发现了一个以睡眠时间持续较短为特征的轨迹、一个以就寝时间持续较晚为特征的轨迹和一个以MPS持续较晚为特征的轨迹。有两个风险因素与这三个不良睡眠健康领域相关:较高的 FAI 会增加持续较短睡眠时间的风险(OR = 1.20,95% CI = 1.11-1.30,p <.001)、持续较晚就寝时间(OR = 1.28,95% CI = 1.19-1.39,p <.001)和持续较晚的 MPS(OR = 1.30,95% CI = 1.22-1.38,p <.001);较高的产妇社会经济地位降低了持续较短睡眠时间的风险(OR = 0.99,95% CI = 0.98-1.00,p = .048)、持续晚睡(OR = 0.98,95% CI = 0.97-0.99,p <.001)和持续晚睡 MPS(OR = 0.99,95% CI = 0.98-0.99,p <.001)的风险降低。结论我们发现了从婴儿期到青春期持续不良睡眠健康的轨迹(即睡眠时间较短、就寝时间较晚和MPS较晚),以及与持续不良睡眠健康领域相关的特定围产期风险因素。
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引用次数: 0
Associations between trauma exposure and irritability within the family unit: a network approach 家庭中的创伤暴露与易怒之间的关系:一种网络方法。
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-06 DOI: 10.1111/jcpp.13998
Grace Cotter, Kristina Morreale, Amanda Valdegas, Meghan Fish, Rebecca Beebe, Damion Grasso, Carla Stover, Wan-Ling Tseng

Background

Pediatric irritability is a pervasive psychiatric symptom, yet its etiology remains elusive. While trauma exposure may contribute to the development of irritability, empirical research is limited. This study examined the prevalence of irritability among trauma-exposed children, identified factors that differentiate trauma-exposed children with and without irritability, and employed a network analysis to uncover associations between irritability and trauma exposure in the family unit.

Methods

Sample included 676 children (56.3% male, mean age = 9.67 ± 3.7 years) and their parents referred by the Connecticut Department of Children and Families to Fathers for Change – a psychotherapy intervention designed to reduce intimate partner violence (IPV) and child maltreatment. Child's trauma exposure, post-traumatic stress disorder (PTSD) symptoms, and irritability were assessed pre-intervention using self- and caregiver-report. Parents self-reported their childhood and adulthood trauma exposures, PTSD symptoms, irritability, psychopathology, and IPV.

Results

Across caregiver- and child-reports, 16%–17% of children exhibited irritability. Irritable children experienced greater trauma exposure, interpersonal violence, emotional abuse, and PTSD severity. They had caregivers, particularly mothers, with greater trauma histories, IPV, and psychopathology. Network analysis revealed 10 nodes directly correlated to child's irritability including child's PTSD severity, parental IPV (specifically psychological violence), and parental psychopathology.

Conclusions

Results provide initial empirical evidence that pediatric irritability is linked to trauma exposure, suggesting trauma histories be considered in the diagnosis and treatment of irritability. Interventions addressing caregiver trauma, IPV, and psychopathology may ameliorate pediatric irritability. Future studies could benefit from adopting network approaches with longitudinal or time series data to elucidate causality and points of intervention.

背景:小儿易激惹是一种普遍的精神症状,但其病因仍难以捉摸。虽然精神创伤可能是导致易怒的原因之一,但实证研究却十分有限。本研究调查了受创伤儿童易激惹的发病率,确定了区分受创伤儿童易激惹与否的因素,并采用网络分析揭示了易激惹与家庭单元中受创伤之间的关联:样本包括 676 名儿童(56.3% 为男性,平均年龄 = 9.67 ± 3.7 岁)及其父母,他们由康涅狄格州儿童和家庭事务部转介至 "父亲促进改变 "项目,这是一项旨在减少亲密伴侣暴力(IPV)和虐待儿童行为的心理治疗干预项目。干预前采用自我报告和照顾者报告的方式对儿童的创伤暴露、创伤后应激障碍(PTSD)症状和易怒性进行了评估。父母则自我报告其童年和成年期的创伤暴露、创伤后应激障碍症状、易怒、精神病理学和 IPV:在护理人员和儿童的报告中,16%-17%的儿童表现出易怒。易怒儿童遭受的创伤、人际暴力、情感虐待和创伤后应激障碍的严重程度更高。他们的照顾者,尤其是母亲,有更多的心理创伤史、人际暴力史和精神病理学史。网络分析显示,有 10 个节点与儿童的易激惹性直接相关,包括儿童创伤后应激障碍的严重程度、父母的 IPV(特别是心理暴力)和父母的精神病理学:研究结果提供了初步的实证证据,证明小儿易怒与创伤暴露有关,建议在诊断和治疗易怒时考虑创伤史。针对照顾者创伤、IPV 和精神病理学的干预措施可能会改善小儿易怒问题。未来的研究可以采用纵向或时间序列数据的网络方法来阐明因果关系和干预要点。
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引用次数: 0
A Bayesian approach for exploring person × environment interaction within the environmental sensitivity meta-framework 在环境敏感性元框架内探索人与环境相互作用的贝叶斯方法
IF 6.5 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-03 DOI: 10.1111/jcpp.14000
Francesca Lionetti, Antonio Calcagnì, Giulio D'Urso, Maria Spinelli, Mirco Fasolo, Michael Pluess, Massimiliano Pastore

Background

For investigating the individual–environment interplay and individual differences in response to environmental exposures as captured by models of environmental sensitivity including Diathesis-stress, Differential Susceptibility, and Vantage Sensitivity, over the last few years, a series of statistical guidelines have been proposed. However, available solutions suffer of computational problems especially relevant when sample size is not sufficiently large, a common condition in observational and clinical studies.

Method

In the current contribution, we propose a Bayesian solution for estimating interaction parameters via Monte Carlo Markov Chains (MCMC), adapting Widaman et al. (Psychological Methods, 17, 2012, 615) Nonlinear Least Squares (NLS) approach.

Results

Findings from an applied exemplification and a simulation study showed that with relatively big samples both MCMC and NLS estimates converged on the same results. Conversely, MCMC clearly outperformed NLS, resolving estimation problems and providing more accurate estimates, particularly with small samples and greater residual variance.

Conclusions

As the body of research exploring the interplay between individual and environmental variables grows, enabling predictions regarding the form of interaction and the extent of effects, the Bayesian approach could emerge as a feasible and readily applicable solution to numerous computational challenges inherent in existing frequentist methods. This approach holds promise for enhancing the trustworthiness of research outcomes, thereby impacting clinical and applied understanding.

背景为了研究个体与环境之间的相互作用以及个体对环境暴露反应的差异,过去几年中,人们提出了一系列统计指南,这些指南可用于环境敏感性模型,包括Diathesis-stress、Differential Susceptibility和Vantage Sensitivity。方法在本论文中,我们提出了通过蒙特卡罗马尔科夫链(MCMC)估计交互作用参数的贝叶斯解决方案,并改编了 Widaman 等人(《心理学方法》,17, 2012, 615)的非线性最小二乘法(NLS)方法。结论随着探索个体变量与环境变量之间相互作用的研究的增加,以及对相互作用形式和影响程度的预测,贝叶斯方法可能成为解决现有频数主义方法固有的众多计算难题的一种可行且易于应用的方法。这种方法有望提高研究成果的可信度,从而影响临床和应用理解。
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引用次数: 0
期刊
Journal of Child Psychology and Psychiatry
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