Pub Date : 2025-12-15DOI: 10.1038/s41579-025-01275-7
Ashley York
A recent study investigated the effect of herpes zoster vaccination at different stages of the dementia disease course.
最近的一项研究调查了带状疱疹疫苗接种在痴呆病程的不同阶段的效果。
{"title":"Immunizing against dementia?","authors":"Ashley York","doi":"10.1038/s41579-025-01275-7","DOIUrl":"10.1038/s41579-025-01275-7","url":null,"abstract":"A recent study investigated the effect of herpes zoster vaccination at different stages of the dementia disease course.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"24 2","pages":"95-95"},"PeriodicalIF":103.3,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1038/s41579-025-01263-x
Understanding the emergence, evolution and spread of viral pathogens is central to improving global health. This Focus issue highlights advances in our understanding of evolving viral pathogens and the surveillance and preparedness strategies that are needed to control them.
{"title":"Evolving viral threats","authors":"","doi":"10.1038/s41579-025-01263-x","DOIUrl":"10.1038/s41579-025-01263-x","url":null,"abstract":"Understanding the emergence, evolution and spread of viral pathogens is central to improving global health. This Focus issue highlights advances in our understanding of evolving viral pathogens and the surveillance and preparedness strategies that are needed to control them.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"24 1","pages":"1-2"},"PeriodicalIF":103.3,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41579-025-01263-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145719852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09DOI: 10.1038/s41579-025-01270-y
Peter Osborne, Keir J. Macartney, Matthew G. Miyada
This Genome Watch discusses the great biosynthetic capacity that has been identified in marine environmental and host-associated microbiomes, along with approaches to facilitate research into these diverse and resource-rich microbial communities.
{"title":"Wringing everything out with bioprospecting","authors":"Peter Osborne, Keir J. Macartney, Matthew G. Miyada","doi":"10.1038/s41579-025-01270-y","DOIUrl":"10.1038/s41579-025-01270-y","url":null,"abstract":"This Genome Watch discusses the great biosynthetic capacity that has been identified in marine environmental and host-associated microbiomes, along with approaches to facilitate research into these diverse and resource-rich microbial communities.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"24 3","pages":"167-167"},"PeriodicalIF":103.3,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145715169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09DOI: 10.1038/s41579-025-01269-5
Andrea Du Toit
This study reports that the commensal gut bacterium Bacteroides thetaiotaomicron establishes distinct subpopulations in response to two secreted, self-targeting effector proteins.
{"title":"Splitting the population in the gut","authors":"Andrea Du Toit","doi":"10.1038/s41579-025-01269-5","DOIUrl":"10.1038/s41579-025-01269-5","url":null,"abstract":"This study reports that the commensal gut bacterium Bacteroides thetaiotaomicron establishes distinct subpopulations in response to two secreted, self-targeting effector proteins.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"24 2","pages":"93-93"},"PeriodicalIF":103.3,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1038/s41579-025-01267-7
Shimona Starling
This paper reports week 96 efficacy and safety findings from a multicentre, open-label phase IIIb trial of intramuscular cabotegravir and rilpivirine in adults living with HIV from Uganda, Kenya and South Africa.
{"title":"Long-acting therapy for HIV shows promise in African trial","authors":"Shimona Starling","doi":"10.1038/s41579-025-01267-7","DOIUrl":"10.1038/s41579-025-01267-7","url":null,"abstract":"This paper reports week 96 efficacy and safety findings from a multicentre, open-label phase IIIb trial of intramuscular cabotegravir and rilpivirine in adults living with HIV from Uganda, Kenya and South Africa.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"24 1","pages":"5-5"},"PeriodicalIF":103.3,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145554409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-17DOI: 10.1038/s41579-025-01264-w
Hsueh-Chien Raymond Cheng, Diego Teixeira
This Genome Watch discusses recent advances in genomic epidemiology that enable the reconstruction of transmission events, with greater resolution and across more complex settings at scale.
{"title":"Unpacking the spread of pathogens","authors":"Hsueh-Chien Raymond Cheng, Diego Teixeira","doi":"10.1038/s41579-025-01264-w","DOIUrl":"10.1038/s41579-025-01264-w","url":null,"abstract":"This Genome Watch discusses recent advances in genomic epidemiology that enable the reconstruction of transmission events, with greater resolution and across more complex settings at scale.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"24 2","pages":"96-96"},"PeriodicalIF":103.3,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145531478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-17DOI: 10.1038/s41579-025-01259-7
Arthur Kocher, Johannes Krause, Maria A. Spyrou
{"title":"Insights into infectious diseases through ancient pathogen genomics","authors":"Arthur Kocher, Johannes Krause, Maria A. Spyrou","doi":"10.1038/s41579-025-01259-7","DOIUrl":"https://doi.org/10.1038/s41579-025-01259-7","url":null,"abstract":"","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"28 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145531479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1038/s41579-025-01256-w
Jan C. Wohlfarth, Danny Ward, Joana Pereira, Marek Basler
{"title":"The type VI secretion system and associated effector proteins","authors":"Jan C. Wohlfarth, Danny Ward, Joana Pereira, Marek Basler","doi":"10.1038/s41579-025-01256-w","DOIUrl":"https://doi.org/10.1038/s41579-025-01256-w","url":null,"abstract":"","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"7 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1038/s41579-025-01262-y
Jessica A. Griffiths, Khemlal Nirmalkar, Wei-Li Wu, Rosa Krajmalnik-Brown, Sarkis K. Mazmanian
{"title":"The gut microbiome shapes social behaviour across animal species","authors":"Jessica A. Griffiths, Khemlal Nirmalkar, Wei-Li Wu, Rosa Krajmalnik-Brown, Sarkis K. Mazmanian","doi":"10.1038/s41579-025-01262-y","DOIUrl":"https://doi.org/10.1038/s41579-025-01262-y","url":null,"abstract":"","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"3 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1038/s41579-025-01258-8
Buse Isbilir, Andriko von Kügelgen, Vikram Alva, Tanmay A. M. Bharat
{"title":"Assembly, architecture and functional roles of microbial surface layers","authors":"Buse Isbilir, Andriko von Kügelgen, Vikram Alva, Tanmay A. M. Bharat","doi":"10.1038/s41579-025-01258-8","DOIUrl":"https://doi.org/10.1038/s41579-025-01258-8","url":null,"abstract":"","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"173 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145498273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}