Pub Date : 2025-04-28DOI: 10.1038/s41570-025-00715-5
Seok-Jin Kim, Raghu V. Maligal-Ganesh, Javeed Mahmood, Pravin Babar, Cafer T. Yavuz
Oxides are integral to heterogeneous catalysis, serving critical roles such as catalyst supports, active materials and electrodes. A highly ordered subset, single-crystalline oxides, have traditionally been used as model catalyst supports in fundamental surface science studies. However, advancements in bulk synthesis have rendered their general use more feasible for real-world applications. In this review, we explore the efficiency of single-crystalline oxides as active metals and supports across a wide range of heterogeneous processes, often performing exceptionally well. Beginning with synthetic methods, we discuss the advantages of single-crystalline oxides in thermo-, electro- and photocatalysis. Previously held conventions about catalytic activity, deactivation and surface–adsorbate interactions are re-evaluated by understanding how these ordered materials behave during the respective reactions. Last, we assess advances in characterization techniques and their impact on designing the next generation of catalysts based on single-crystalline oxides. Single-crystalline oxides offer well-defined surfaces, enabling superior control of their chemistry with tunable catalytic activity and enhanced stability. This review summarizes new advances in their synthesis and analysis, and their prominence in heterogeneous catalysis, namely thermo-, electro- and photocatalysis.
{"title":"Structural control over single-crystalline oxides for heterogeneous catalysis","authors":"Seok-Jin Kim, Raghu V. Maligal-Ganesh, Javeed Mahmood, Pravin Babar, Cafer T. Yavuz","doi":"10.1038/s41570-025-00715-5","DOIUrl":"10.1038/s41570-025-00715-5","url":null,"abstract":"Oxides are integral to heterogeneous catalysis, serving critical roles such as catalyst supports, active materials and electrodes. A highly ordered subset, single-crystalline oxides, have traditionally been used as model catalyst supports in fundamental surface science studies. However, advancements in bulk synthesis have rendered their general use more feasible for real-world applications. In this review, we explore the efficiency of single-crystalline oxides as active metals and supports across a wide range of heterogeneous processes, often performing exceptionally well. Beginning with synthetic methods, we discuss the advantages of single-crystalline oxides in thermo-, electro- and photocatalysis. Previously held conventions about catalytic activity, deactivation and surface–adsorbate interactions are re-evaluated by understanding how these ordered materials behave during the respective reactions. Last, we assess advances in characterization techniques and their impact on designing the next generation of catalysts based on single-crystalline oxides. Single-crystalline oxides offer well-defined surfaces, enabling superior control of their chemistry with tunable catalytic activity and enhanced stability. This review summarizes new advances in their synthesis and analysis, and their prominence in heterogeneous catalysis, namely thermo-, electro- and photocatalysis.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 6","pages":"397-414"},"PeriodicalIF":51.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-28DOI: 10.1038/s41570-025-00711-9
Martin Bizzarro, Anders Johansen, Caroline Dorn
Planets form and obtain their compositions from the leftover material present in protoplanetary disks of dust and gas surrounding young stars. The chemical make-up of a disk influences every aspect of planetary composition, including their overall chemical properties, volatile content, atmospheric composition and potential for habitability. This Review discusses our knowledge of the chemical and isotopic composition of Solar System materials and how this information can be used to place constraints on the formation pathways of terrestrial planets. We conclude that planetesimal formation by the streaming instability followed by rapid accretion of drifting pebbles within the protoplanetary disk lifetime reproduces most of the chemical and isotopic observables in the Solar System. This finding has important implications for planetary habitability beyond the Solar System because in pebble accretion, volatiles important for life are accreted during the main growth phase of rocky planets as opposed to the late stage. Finally, we explore how bulk chemical inventories and masses of planetary bodies control the composition of their primordial atmospheres and their potential to develop habitable conditions. Leftover materials in protoplanetary disks form planets, shaping their chemistry, atmospheres and habitability. This Review highlights how planetesimal formation and pebble accretion explain planetary compositions, influencing volatile delivery and atmospheric development, with implications for planetary habitability beyond our Solar System.
{"title":"The cosmochemistry of planetary systems","authors":"Martin Bizzarro, Anders Johansen, Caroline Dorn","doi":"10.1038/s41570-025-00711-9","DOIUrl":"10.1038/s41570-025-00711-9","url":null,"abstract":"Planets form and obtain their compositions from the leftover material present in protoplanetary disks of dust and gas surrounding young stars. The chemical make-up of a disk influences every aspect of planetary composition, including their overall chemical properties, volatile content, atmospheric composition and potential for habitability. This Review discusses our knowledge of the chemical and isotopic composition of Solar System materials and how this information can be used to place constraints on the formation pathways of terrestrial planets. We conclude that planetesimal formation by the streaming instability followed by rapid accretion of drifting pebbles within the protoplanetary disk lifetime reproduces most of the chemical and isotopic observables in the Solar System. This finding has important implications for planetary habitability beyond the Solar System because in pebble accretion, volatiles important for life are accreted during the main growth phase of rocky planets as opposed to the late stage. Finally, we explore how bulk chemical inventories and masses of planetary bodies control the composition of their primordial atmospheres and their potential to develop habitable conditions. Leftover materials in protoplanetary disks form planets, shaping their chemistry, atmospheres and habitability. This Review highlights how planetesimal formation and pebble accretion explain planetary compositions, influencing volatile delivery and atmospheric development, with implications for planetary habitability beyond our Solar System.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 6","pages":"378-396"},"PeriodicalIF":51.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-28DOI: 10.1038/s41570-025-00714-6
Xu Liu, Xu Dong, Henry Adenusi, Yuping Wu, Stefano Passerini
The potential increase in cost of lithium-ion batteries owing to the limited supply of lithium has prompted investigations into alternative and complementary rechargeable batteries that use post-lithium charge carriers with higher elemental abundance. However, achieving highly reversible post-lithium metal anodes with sufficient kinetics remains challenging. The addition of co-solvents to conventional electrolytes is emerging as an important strategy to resolve these issues. In this Perspective, we discuss the progress of the co-solvent strategy for sodium, potassium, magnesium, calcium, zinc and aluminium post-lithium metal batteries. The coordination ability of co-solvents with post-lithium charge carriers is presented as a useful guide for selecting co-solvents for the respective battery electrolytes, owing to its correlation with several influential factors that affect the electrochemical performance of the metal anodes, such as solvation structure, de-solvation process and solid electrolyte interphase formation. Additionally, a discussion is provided on the importance of unravelling the effects beyond the solvation sheath of cationic charge carriers and for the development of sustainable electrolytes. The coordination ability of co-solvents with cationic charge carriers is discussed as a guide for selecting co-solvents for various post-lithium metal batteries. Effects beyond the solvation sheath of cationic charge carriers and the sustainable development of electrolytes are necessary for improving batteries in the future.
{"title":"Co-solvent strategy for rechargeable post-lithium metal batteries","authors":"Xu Liu, Xu Dong, Henry Adenusi, Yuping Wu, Stefano Passerini","doi":"10.1038/s41570-025-00714-6","DOIUrl":"10.1038/s41570-025-00714-6","url":null,"abstract":"The potential increase in cost of lithium-ion batteries owing to the limited supply of lithium has prompted investigations into alternative and complementary rechargeable batteries that use post-lithium charge carriers with higher elemental abundance. However, achieving highly reversible post-lithium metal anodes with sufficient kinetics remains challenging. The addition of co-solvents to conventional electrolytes is emerging as an important strategy to resolve these issues. In this Perspective, we discuss the progress of the co-solvent strategy for sodium, potassium, magnesium, calcium, zinc and aluminium post-lithium metal batteries. The coordination ability of co-solvents with post-lithium charge carriers is presented as a useful guide for selecting co-solvents for the respective battery electrolytes, owing to its correlation with several influential factors that affect the electrochemical performance of the metal anodes, such as solvation structure, de-solvation process and solid electrolyte interphase formation. Additionally, a discussion is provided on the importance of unravelling the effects beyond the solvation sheath of cationic charge carriers and for the development of sustainable electrolytes. The coordination ability of co-solvents with cationic charge carriers is discussed as a guide for selecting co-solvents for various post-lithium metal batteries. Effects beyond the solvation sheath of cationic charge carriers and the sustainable development of electrolytes are necessary for improving batteries in the future.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 6","pages":"415-426"},"PeriodicalIF":51.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-14DOI: 10.1038/s41570-025-00706-6
Patrick Commins, Marieh B. Al-Handawi, Panče Naumov
Self-healing is an intrinsically exciting concept as it applies to the process of recovery, a commonplace phenomenon found in living organisms. Self-healing of artificial materials is as beneficial to living creatures as it is to materials science, wherein the effect can considerably prolong lifetimes. Although self-healing sodium chloride crystals were discovered in the 1980s, the field entered a renaissance when healing was observed in the emerging materials class of molecular crystals in 2016. Self-healing properties in polymers, cementitious materials, and coatings have already found commercial applications. The reinvigorated interest in self-healing molecular crystals stems from their prospects as durable, lightweight and flexible emissive or electronic materials. Ideally being defectless and ordered media, organic crystals have unique optical, mechanical and electrical properties, and the possibility of self-healing substantially increases their viability for smart devices. Self-healing crystals are an emerging class of materials that are highly responsive to dynamic stimuli. This Perspective gives an overview of the field since its inception, highlights current design principles, and discusses the methodologies used to characterize healed crystals.
{"title":"Self-healing crystals","authors":"Patrick Commins, Marieh B. Al-Handawi, Panče Naumov","doi":"10.1038/s41570-025-00706-6","DOIUrl":"10.1038/s41570-025-00706-6","url":null,"abstract":"Self-healing is an intrinsically exciting concept as it applies to the process of recovery, a commonplace phenomenon found in living organisms. Self-healing of artificial materials is as beneficial to living creatures as it is to materials science, wherein the effect can considerably prolong lifetimes. Although self-healing sodium chloride crystals were discovered in the 1980s, the field entered a renaissance when healing was observed in the emerging materials class of molecular crystals in 2016. Self-healing properties in polymers, cementitious materials, and coatings have already found commercial applications. The reinvigorated interest in self-healing molecular crystals stems from their prospects as durable, lightweight and flexible emissive or electronic materials. Ideally being defectless and ordered media, organic crystals have unique optical, mechanical and electrical properties, and the possibility of self-healing substantially increases their viability for smart devices. Self-healing crystals are an emerging class of materials that are highly responsive to dynamic stimuli. This Perspective gives an overview of the field since its inception, highlights current design principles, and discusses the methodologies used to characterize healed crystals.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 5","pages":"343-355"},"PeriodicalIF":51.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143827244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-13DOI: 10.1038/s41570-025-00716-4
Eleanor Campbell, Stephanie Greed
Ahead of her 65th birthday, Eleanor Campbell, the Chair of Chemistry at the University of Edinburgh, discusses her life from a fascination with science fiction growing up to her successful research career exploring carbon nanomaterials.
{"title":"A career in pursuit of the fundamentals","authors":"Eleanor Campbell, Stephanie Greed","doi":"10.1038/s41570-025-00716-4","DOIUrl":"10.1038/s41570-025-00716-4","url":null,"abstract":"Ahead of her 65th birthday, Eleanor Campbell, the Chair of Chemistry at the University of Edinburgh, discusses her life from a fascination with science fiction growing up to her successful research career exploring carbon nanomaterials.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 5","pages":"279-280"},"PeriodicalIF":51.7,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-11DOI: 10.1038/s41570-025-00704-8
Brennan Ashwood, Andrei Tokmakoff
The hybridization of short nucleic acid strands is a remarkable spontaneous process that is foundational to biotechnology and nanotechnology and plays a crucial role in gene expression, editing and DNA repair. Decades of research into the mechanism of hybridization have resulted in a deep understanding of its thermodynamics, but many questions remain regarding its kinetics and dynamics. Recent advances in experiments and molecular dynamics simulations of nucleic acids are enabling more direct insight into the structural dynamics of hybridization, which can test long-standing assumptions regarding its mechanism. In this Review, we summarize the current state of knowledge of hybridization kinetics, discuss the barriers to a molecular description of hybridization dynamics, and highlight the new approaches that have begun uncovering the dynamics of hybridization and the duplex ensemble. The kinetics and dynamics of hybridization are highly sensitive to the composition of nucleic acids, and we emphasize recent discoveries and open questions on the role of nucleobase sequence and chemical modifications. This Review summarizes the current state of knowledge of DNA and RNA oligonucleotide hybridization kinetics, discusses new insights into the dynamics of hybridization and the duplex, and highlights strategies to probe hybridization at a deeper molecular level.
{"title":"Kinetics and dynamics of oligonucleotide hybridization","authors":"Brennan Ashwood, Andrei Tokmakoff","doi":"10.1038/s41570-025-00704-8","DOIUrl":"10.1038/s41570-025-00704-8","url":null,"abstract":"The hybridization of short nucleic acid strands is a remarkable spontaneous process that is foundational to biotechnology and nanotechnology and plays a crucial role in gene expression, editing and DNA repair. Decades of research into the mechanism of hybridization have resulted in a deep understanding of its thermodynamics, but many questions remain regarding its kinetics and dynamics. Recent advances in experiments and molecular dynamics simulations of nucleic acids are enabling more direct insight into the structural dynamics of hybridization, which can test long-standing assumptions regarding its mechanism. In this Review, we summarize the current state of knowledge of hybridization kinetics, discuss the barriers to a molecular description of hybridization dynamics, and highlight the new approaches that have begun uncovering the dynamics of hybridization and the duplex ensemble. The kinetics and dynamics of hybridization are highly sensitive to the composition of nucleic acids, and we emphasize recent discoveries and open questions on the role of nucleobase sequence and chemical modifications. This Review summarizes the current state of knowledge of DNA and RNA oligonucleotide hybridization kinetics, discusses new insights into the dynamics of hybridization and the duplex, and highlights strategies to probe hybridization at a deeper molecular level.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 5","pages":"305-327"},"PeriodicalIF":51.7,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143819404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-07DOI: 10.1038/s41570-025-00702-w
Irea Mosquera-Lois, Yi-Teng Huang, Hugh Lohan, Junzhi Ye, Aron Walsh, Robert L. Z. Hoye
Lead halide perovskites (LHPs) have shot to prominence as efficient energy-conversion materials that can be processed using cost-effective fabrication methods. A reason for their exceptional performance is their crystallographic defect tolerance, enabling long charge-carrier lifetimes despite high defect densities. Achieving defect tolerance in broader classes of materials would impact on the semiconductor industry substantially. Considerable efforts have been made to understand the origins of defect tolerance, so as to design stable and nontoxic alternatives to LHPs. However, understanding defect tolerance in LHPs is far from straightforward. This Review discusses the models proposed for defect tolerance in halide perovskites, evaluating the experimental and theoretical support for these models, as well as their limitations. We also cover attempts to apply these models to identify materials beyond LHPs that could exhibit defect tolerance. Finally, we discuss the experimental methods used to understand defects in mixed ionic–electronic conductors, as well as the important information that is necessary for a deeper understanding, in order to develop improved models that enable the design of defect-tolerant semiconductors. Defect tolerance is a key factor behind the exceptional optoelectronic properties of lead halide perovskites, but it is not well understood. This Review discusses the models for defect tolerance and what has been learnt in generalizing these models to lead-free, stable materials.
{"title":"Multifaceted nature of defect tolerance in halide perovskites and emerging semiconductors","authors":"Irea Mosquera-Lois, Yi-Teng Huang, Hugh Lohan, Junzhi Ye, Aron Walsh, Robert L. Z. Hoye","doi":"10.1038/s41570-025-00702-w","DOIUrl":"10.1038/s41570-025-00702-w","url":null,"abstract":"Lead halide perovskites (LHPs) have shot to prominence as efficient energy-conversion materials that can be processed using cost-effective fabrication methods. A reason for their exceptional performance is their crystallographic defect tolerance, enabling long charge-carrier lifetimes despite high defect densities. Achieving defect tolerance in broader classes of materials would impact on the semiconductor industry substantially. Considerable efforts have been made to understand the origins of defect tolerance, so as to design stable and nontoxic alternatives to LHPs. However, understanding defect tolerance in LHPs is far from straightforward. This Review discusses the models proposed for defect tolerance in halide perovskites, evaluating the experimental and theoretical support for these models, as well as their limitations. We also cover attempts to apply these models to identify materials beyond LHPs that could exhibit defect tolerance. Finally, we discuss the experimental methods used to understand defects in mixed ionic–electronic conductors, as well as the important information that is necessary for a deeper understanding, in order to develop improved models that enable the design of defect-tolerant semiconductors. Defect tolerance is a key factor behind the exceptional optoelectronic properties of lead halide perovskites, but it is not well understood. This Review discusses the models for defect tolerance and what has been learnt in generalizing these models to lead-free, stable materials.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 5","pages":"287-304"},"PeriodicalIF":51.7,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-04DOI: 10.1038/s41570-025-00705-7
Irene Regeni, Sylvestre Bonnet
Supramolecular chemistry provides a range of ‘weak’ intermolecular interactions that allow drugs and prodrugs to self-assemble. In the complex biological setting of blood and tumours, these interactions must be stable enough for efficient and selective drug delivery to the tumour site, but weak enough to allow the release of the cytotoxic load. The non-covalent nature of supramolecular interactions enables the detachment of smaller (pro)drug monomers that can penetrate cancer cells differently to the original nanoparticles. Hypoxic tumours show low oxygen levels due to poor vascularization, which poses challenges for drug delivery and generates biological resistances. Supramolecular building blocks specifically designed for hypoxic tumours offer targeted activation of prodrug self-assemblies, enhancing effectiveness against hypoxic cancer cells and hypoxic regions in tumours. This Review explores how supramolecular chemistry can improve (pro)drug delivery and activation in hypoxic tumours. Hypoxic tumours present considerable challenges in cancer treatment owing to their specific chemistry, biology and physics, which leads to resistances to conventional therapies. This Review explores innovative strategies based on supramolecular chemistry to overcome these obstacles and discusses future research directions that might help translating supramolecular approaches to the clinics.
{"title":"Supramolecular approaches for the treatment of hypoxic regions in tumours","authors":"Irene Regeni, Sylvestre Bonnet","doi":"10.1038/s41570-025-00705-7","DOIUrl":"10.1038/s41570-025-00705-7","url":null,"abstract":"Supramolecular chemistry provides a range of ‘weak’ intermolecular interactions that allow drugs and prodrugs to self-assemble. In the complex biological setting of blood and tumours, these interactions must be stable enough for efficient and selective drug delivery to the tumour site, but weak enough to allow the release of the cytotoxic load. The non-covalent nature of supramolecular interactions enables the detachment of smaller (pro)drug monomers that can penetrate cancer cells differently to the original nanoparticles. Hypoxic tumours show low oxygen levels due to poor vascularization, which poses challenges for drug delivery and generates biological resistances. Supramolecular building blocks specifically designed for hypoxic tumours offer targeted activation of prodrug self-assemblies, enhancing effectiveness against hypoxic cancer cells and hypoxic regions in tumours. This Review explores how supramolecular chemistry can improve (pro)drug delivery and activation in hypoxic tumours. Hypoxic tumours present considerable challenges in cancer treatment owing to their specific chemistry, biology and physics, which leads to resistances to conventional therapies. This Review explores innovative strategies based on supramolecular chemistry to overcome these obstacles and discusses future research directions that might help translating supramolecular approaches to the clinics.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 6","pages":"365-377"},"PeriodicalIF":51.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-04DOI: 10.1038/s41570-025-00710-w
Dylan Klein, Vikas Nanda
In 1998, a protein structure that had not yet been experimentally observed was designed from scratch. 27 years later this work still demonstrates the power of a field that is undergoing an exciting renaissance thanks to advances in machine learning.
{"title":"The proteins that could be","authors":"Dylan Klein, Vikas Nanda","doi":"10.1038/s41570-025-00710-w","DOIUrl":"10.1038/s41570-025-00710-w","url":null,"abstract":"In 1998, a protein structure that had not yet been experimentally observed was designed from scratch. 27 years later this work still demonstrates the power of a field that is undergoing an exciting renaissance thanks to advances in machine learning.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 5","pages":"283-284"},"PeriodicalIF":51.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-02DOI: 10.1038/s41570-025-00713-7
Luis M. Aguirre Quintana, Leander I. Held
A berkelium metallocene complex was isolated and structurally characterized for the first time. These findings elevate our understanding of chemical bonding and inform on the future design of f-element quantum materials.
我们首次分离出了锫金属复合物，并确定了其结构特征。这些发现提升了我们对化学键的理解，并为未来设计 f 元素量子材料提供了参考。
{"title":"A new actinide sandwich on the menu","authors":"Luis M. Aguirre Quintana, Leander I. Held","doi":"10.1038/s41570-025-00713-7","DOIUrl":"10.1038/s41570-025-00713-7","url":null,"abstract":"A berkelium metallocene complex was isolated and structurally characterized for the first time. These findings elevate our understanding of chemical bonding and inform on the future design of f-element quantum materials.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"9 5","pages":"282-282"},"PeriodicalIF":51.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143758755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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