Nature Human Behaviour最新文献

Improving population well-being is increasingly recognized as a global priority, yet evidence on the comparative effectiveness of well-being-focused interventions in adults is fragmented. Here we conduct a preregistered systematic review and network meta-analysis (PROSPERO CRD42023403480) of randomized controlled trials evaluating well-being interventions in adults without diagnosed conditions. Searches of MEDLINE, PsycINFO, CENTRAL and Scopus (to March 2023) identified 183 trials (n = 22,811). Interventions included mindfulness-based, compassion-based, acceptance and commitment therapy and positive psychology interventions, as well as exercise, yoga, educational, nature-based programmes and combined exercise-psychological approaches. Risk of bias was assessed using RoB 2, and data were synthesized using random-effects network meta-analysis. Most interventions improved well-being compared with inactive controls. Combined exercise-psychological interventions produced the largest effect (standardized mean difference of 0.73, 95% confidence interval 0.27 to 1.20). Mindfulness, compassion, single positive psychology, yoga and exercise interventions demonstrated moderate, consistent effects (standardized mean difference of 0.41-0.49), with no significant differences between interventions. Nature-based interventions were not significantly more effective than controls, but evidence was limited by conceptual and methodological heterogeneity. Risk of bias was frequently moderate to high, and funnel plot asymmetry suggested potential publication bias. However, multiple sensitivity analyses (including grey literature, excluding studies with high risk of bias and small studies) supported the robustness of overall conclusions. Most comparisons (71%) were rated as moderate in certainty of evidence using CINEMA. These findings provide an integrated synthesis of the well-being intervention literature and highlight priority areas for future interdisciplinary, methodologically robust research. No external funding was received.

The Eastern Zhou period (771-221 BC), characterized by social stratification, was marked by important inequality. Here the authors analyse 32 skeletons from Songzhuang Cemetery in Henan Province using sex-specific peptides, ancient DNA and isotopes to explore multidimensional inequality in sexes, diet and mobility. DNA and proteomic analyses show that young women were marginalized as sacrificial victims (22 out of 26 human sacrifices were female). Carbon and nitrogen isotopic analyses suggest dietary differences by social class, with the nobility consuming more high-protein and millet-based diets than sacrificial companions, who themselves show intra-group dietary variation (δ¹³C_bone,nobles = -8.6‰; δ¹³C_{bone,human sacrifice group one} = -10.9‰; δ¹³C_{bone,human sacrifice group two} = -14.1‰; δ¹⁵N_bone,nobles = 11.6‰; δ¹⁵N_{bone,human sacrifice group one} = 8.5‰; δ¹⁵N_{bone,human sacrifice group two} = 7.7‰). Enamel and dentin isotope data indicate that these dietary inequalities were established from childhood (δ¹³C_{enamel,nobles} = -1.5‰; δ¹³C_{enamel,human sacrifice group one} = -3.8‰; δ¹³C_{enamel,human sacrifice group two} = -6.9‰). Strontium and oxygen isotope evidence shows that a high proportion of the nobles were non-local migrants. Genetic analysis reveals a genealogy linking four noblewomen to a sacrificial victim, highlighting the importance of kinship and marital alliances in maintaining social status. Despite class rigidity, dental isotope sequences in M18 reveal that two individuals experienced childhood dietary shifts, indicating rare class mobility.