Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.61-65
O. Tsyhykalo, N. Kozariichuk, Т. V. Protsak, O. S. Zabrods’ka
{"title":"Peculiarities of the morphogenesis and topography of the human orbit.","authors":"O. Tsyhykalo, N. Kozariichuk, Т. V. Protsak, O. S. Zabrods’ka","doi":"10.26641/1997-9665.2019.4.61-65","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.61-65","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78137925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.24-33
I. Liskina, V. P. Silchenko, L. Zahaba, S. Kuzovkova
Background. Intravital differential diagnostics of HIV-associated of the thorax pathology is complex. Currently in the diagnostic algorithm various mini-invasive diagnostic procedures with morphological examination of biopsy material are widely used. Objective – to evaluate the effectiveness of the morphological diagnostics of the thorax diseases in HIV-infected patients. Methods . A retrospective analysis of 205 cases of a morphological study of a biopsy and surgical material from hospitalized HIV-infected patients of a phthisiopulmonological profile over a 5-year period was carried out. Comparison of the histological conclusion with the final clinical diagnosis was made. Results. Among all hospitalized HIV patients in 45,5 % of cases in the diagnostic algorithm of the thorax pathology there was a need for a morphological study. Endoscopic procedures with a biopsy were performed in 93,6 % of cases; typical surgeries – in 5,8 % of cases. In 60,0 % of cases the material was obtained in video assisted thoracoscopy. Histological examination of the lungs was carried out in 23,4 %, lymph nodes in 25,4 % and parietal pleura in 50,7 % of cases. Conclusion. In 77,1 % of cases of all histological studies the final clinical diagnosis and histological conclusion coincided. In 12,7 % of the histological examination there was a clarification of the preliminary clinical diagnosis. The effectiveness of histological diagnostics of thorax diseases in HIV-infected patients was: lung pathology – 81,3 %, lymphatic system pathology – 84,6 % and pleural pathology – 95,2 %. The overall effectiveness of histological examination of biopsy and surgical material among hospitalized HIV-infected patients was 89,8 %.
{"title":"Morphological diagnostics of pathology of the thorax organs in HIV-infected patients of a phthisiopulmonology hospital.","authors":"I. Liskina, V. P. Silchenko, L. Zahaba, S. Kuzovkova","doi":"10.26641/1997-9665.2019.4.24-33","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.24-33","url":null,"abstract":"Background. Intravital differential diagnostics of HIV-associated of the thorax pathology is complex. Currently in the diagnostic algorithm various mini-invasive diagnostic procedures with morphological examination of biopsy material are widely used. Objective – to evaluate the effectiveness of the morphological diagnostics of the thorax diseases in HIV-infected patients. Methods . A retrospective analysis of 205 cases of a morphological study of a biopsy and surgical material from hospitalized HIV-infected patients of a phthisiopulmonological profile over a 5-year period was carried out. Comparison of the histological conclusion with the final clinical diagnosis was made. Results. Among all hospitalized HIV patients in 45,5 % of cases in the diagnostic algorithm of the thorax pathology there was a need for a morphological study. Endoscopic procedures with a biopsy were performed in 93,6 % of cases; typical surgeries – in 5,8 % of cases. In 60,0 % of cases the material was obtained in video assisted thoracoscopy. Histological examination of the lungs was carried out in 23,4 %, lymph nodes in 25,4 % and parietal pleura in 50,7 % of cases. Conclusion. In 77,1 % of cases of all histological studies the final clinical diagnosis and histological conclusion coincided. In 12,7 % of the histological examination there was a clarification of the preliminary clinical diagnosis. The effectiveness of histological diagnostics of thorax diseases in HIV-infected patients was: lung pathology – 81,3 %, lymphatic system pathology – 84,6 % and pleural pathology – 95,2 %. The overall effectiveness of histological examination of biopsy and surgical material among hospitalized HIV-infected patients was 89,8 %.","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83633495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.16-23
V. Kosharnyi, V. G. Rutgizer, L. Abdul-Ohly, K. A. Kushnaryova, N. Bondarenko, I. Tverdokhlib
{"title":"Ultrastructure of mitochondrial apparatus of left ventricle cardiomyocyte of rats after different exposures of electromagnetic radiation under hypothyroidism.","authors":"V. Kosharnyi, V. G. Rutgizer, L. Abdul-Ohly, K. A. Kushnaryova, N. Bondarenko, I. Tverdokhlib","doi":"10.26641/1997-9665.2019.4.16-23","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.16-23","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73268147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.6-9
O. Hryhorieva, V. I. Pivtorak, E. R. Skakovsky, S. Hryhoriev
Background. Due to the increased requirement for evaluation of safety, drugsafety and toxicological testing of new drugs take one of the most important places in pre-clinical studies. Objective: to identify features of the macro – and microstructure of the liver, pancreas, stomach, small intestine and colon in the study of chronic toxicity of tablets "Trianol". Methods. This study researched the characteristics of macro- and microstructure of the liver, pancreas, stomach, small intestine and colon in the study of chronic toxicity of tablets "Trianol". Experiments performed on rats of Vistar line of both sexes weighing 180-230g, obtained from the nursery of the Institute of Pharmacology and toxicology of NAMS of Ukraine, contained in a vivarium and receiving standard diet. When working with experimental animals was guided by the requirements of the "European Convention for the protection of vertebrate animals used for experimental and other scientific purposes" (Strasbourg, 18.03.86). Studied the toxicity of three doses of “Trianol”: minimum (therapeutic) dose for tablets amounted to 50.0 mg/kg, intermediate – 250,0 mg/kg, maximum (subtoxic) – 500,0 mg/kg. Results . It is established that chronic introduction of trianol in a therapeutic dose induces hypertrophy of the gastric mucosa and the appearance of liver hepatocytes with signs of degeneration in cytoplasm. Identified changes are reversible. Conclusion . Intermediate and subtoxic doses cause the appearance of toxic changes in the form of swelling of the mucous membrane of the stomach, degenerative changes in cells and destruction of liver cells that must be considered when prescribing the drug. Immunotoxicaction on Peyer’s patch is not revealed.
{"title":"Features of macro- and microstructure of the liver, pancreas, stomach, small and large intestinesin the study of chronic toxicity of tablets \"Trianol\".","authors":"O. Hryhorieva, V. I. Pivtorak, E. R. Skakovsky, S. Hryhoriev","doi":"10.26641/1997-9665.2019.4.6-9","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.6-9","url":null,"abstract":"Background. Due to the increased requirement for evaluation of safety, drugsafety and toxicological testing of new drugs take one of the most important places in pre-clinical studies. Objective: to identify features of the macro – and microstructure of the liver, pancreas, stomach, small intestine and colon in the study of chronic toxicity of tablets \"Trianol\". Methods. This study researched the characteristics of macro- and microstructure of the liver, pancreas, stomach, small intestine and colon in the study of chronic toxicity of tablets \"Trianol\". Experiments performed on rats of Vistar line of both sexes weighing 180-230g, obtained from the nursery of the Institute of Pharmacology and toxicology of NAMS of Ukraine, contained in a vivarium and receiving standard diet. When working with experimental animals was guided by the requirements of the \"European Convention for the protection of vertebrate animals used for experimental and other scientific purposes\" (Strasbourg, 18.03.86). Studied the toxicity of three doses of “Trianol”: minimum (therapeutic) dose for tablets amounted to 50.0 mg/kg, intermediate – 250,0 mg/kg, maximum (subtoxic) – 500,0 mg/kg. Results . It is established that chronic introduction of trianol in a therapeutic dose induces hypertrophy of the gastric mucosa and the appearance of liver hepatocytes with signs of degeneration in cytoplasm. Identified changes are reversible. Conclusion . Intermediate and subtoxic doses cause the appearance of toxic changes in the form of swelling of the mucous membrane of the stomach, degenerative changes in cells and destruction of liver cells that must be considered when prescribing the drug. Immunotoxicaction on Peyer’s patch is not revealed.","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"283 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76839002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.55-60
S. Dubinin, V. O. Piliuhin, A. Vatsenko, N. Ulanovskaya–Tsyba, N. Perederii, O. Ryabushko, O. V. Ovcharenko, O. Klepets
{"title":"Optimization of educational activity and support of educational process at teaching on medical biology.","authors":"S. Dubinin, V. O. Piliuhin, A. Vatsenko, N. Ulanovskaya–Tsyba, N. Perederii, O. Ryabushko, O. V. Ovcharenko, O. Klepets","doi":"10.26641/1997-9665.2019.4.55-60","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.55-60","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74787406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.43-49
M. Shyshkin, T. A. Khrystenko
{"title":"Comparative immunohistochemical study of neoangiogenesis in polyps and adenocarcinoma of the distal colon.","authors":"M. Shyshkin, T. A. Khrystenko","doi":"10.26641/1997-9665.2019.4.43-49","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.43-49","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83991521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.76-89
Editorial office Of journal "Morphologia"
{"title":"Histology: A Text and Atlas: With Correlated Cell and Molecular Biology. Eighth Edition, 2018 Authors: Wojciech Pawlina; Michael H. Ross","authors":"Editorial office Of journal \"Morphologia\"","doi":"10.26641/1997-9665.2019.4.76-89","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.76-89","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86343364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.34-42
S. Potapov, D. I. Halata, O. Pliten, R. Sidorenko, O. N. Kolyada
{"title":"Peculiarities of expression of metalloproteinases in testicular germ cell tumors.","authors":"S. Potapov, D. I. Halata, O. Pliten, R. Sidorenko, O. N. Kolyada","doi":"10.26641/1997-9665.2019.4.34-42","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.34-42","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90979048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.26641/1997-9665.2019.4.10-15
E. A. Hrygorieva, I. Y. Mamay
{"title":"Hippocampus and dentate gyrus morphological сhanges in posterity of female rats after receiving PgE2 for labor induction.","authors":"E. A. Hrygorieva, I. Y. Mamay","doi":"10.26641/1997-9665.2019.4.10-15","DOIUrl":"https://doi.org/10.26641/1997-9665.2019.4.10-15","url":null,"abstract":"","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87996530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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