Nutrition Research最新文献_第9页

Plasma advanced glycation products are associated with increased risk of depression in middle-aged and elderly Chinese adults 血浆晚期糖化产物与中国中老年人抑郁症风险增加相关

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-24 DOI: 10.1016/j.nutres.2025.06.004

Yebing Zhang , Yu Zhang , Fengfei Xie , Nimei Zeng , Renfang Han , Yun Wang , Zhongxiao Wan

Depression is becoming a critical health challenge for the middle-aged and elderly populations. Existing evidence on the associations between body accumulations of advanced glycation end products (AGEs) and depression remain inconsistent. We hypothesized that plasma AGEs concentration might be positively correlated with the incidence of depression in middle-aged and elderly adults. In this cross-sectional study with 586 participants (201 males and 385 females, mean age: 62.18 years old) from Suzhou city, depression was assessed via the Center for Epidemiologic Studies Depression scale 10-item version (CES-D-10). Plasma AGEs of free Nε-carboxymethyl-L-lysine (CML), Nε-(1-carboxyethyl) lysine (CEL), and Nδ-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine (MG-H1), as well as protein bound CEL and CML were measured with ultraperformance liquid chromatography and tandem mass spectrometry. Multivariate linear regression analysis and logistic regression analysis were utilized to determine the associations between specific plasma AGEs and CES-D-10 score and the incidence of depression, respectively. The incidence of depression was 8.02%. Plasma protein bound CEL and CML concentration were positively correlated with CES-D-10 score (CEL: β=0.12, P=0.018; CML: β=0.14; P=0.034) in the linear regression analysis. Compared to those below the median concentration of bound CEL and CML, participants with bound CEL and CML concentration above the median had increased risk of depression [ORs (95% CI): 2.33 (1.13-4.84), P=0.023, and ORs (95% CI): 2.27 (1.16-4.43), P=0.016, respectively] in the logistic regression analysis. Elevated plasma bound CEL and CML might be associated with increased risk of depression. Further studies are required to confirm the associations between specific AGEs and the risk of depression.

抑郁症正成为中老年人群面临的重大健康挑战。关于晚期糖基化终产物（AGEs）的体内积累与抑郁症之间关系的现有证据仍然不一致。我们假设血浆AGEs浓度可能与中老年人抑郁症的发病率呈正相关。本研究采用美国流行病学研究中心抑郁量表10题版（CES-D-10）对来自苏州市的586名参与者（201名男性，385名女性，平均年龄：62.18岁）进行抑郁评估。采用超高效液相色谱和串联质谱法测定血浆游离Nε-羧甲基-l -赖氨酸（CML）、Nε-（1-羧乙基）赖氨酸（CEL）和Nδ-（5-氢-5-甲基-4-咪唑啉-2-基）鸟氨酸（MG-H1）的AGEs以及蛋白结合的CEL和CML。采用多元线性回归分析和logistic回归分析分别确定特异性血浆AGEs和CES-D-10评分与抑郁发生率的关系。抑郁发生率为8.02%。血浆蛋白结合CEL和CML浓度与CES-D-10评分呈正相关(CEL: β=0.12， P=0.018；CML:β= 0.14;P=0.034)。在logistic回归分析中，与低于结合型CEL和CML中位数浓度的受试者相比，结合型CEL和CML中位数浓度高于中位数的受试者抑郁风险增加[or (95% CI): 2.33 (1.13-4.84)， P=0.023, or (95% CI): 2.27 (1.16-4.43)， P=0.016]。血浆结合的CEL和CML升高可能与抑郁症风险增加有关。需要进一步的研究来证实特定年龄与抑郁症风险之间的联系。

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Editorial office and Board Members 编辑部和董事会成员

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-24 DOI: 10.1016/S0271-5317(25)00082-X

引用次数: 0

Sweetened beverage intake across moderate intake range is not associated with pregnancy-related weight change or biomarkers of glycemic control 在适度摄入范围内摄入含糖饮料与妊娠相关体重变化或血糖控制的生物标志物无关

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-21 DOI: 10.1016/j.nutres.2025.06.007

Mia G. Kwan , Leah M. Lipsky , Kyle S. Burger , Grace E. Shearrer , Tonja R. Nansel

While sweetened beverage intake is associated with weight and glycemic outcomes in the general population, relations during pregnancy are unclear. This prospective observational study tested the hypothesis that greater sweetened beverage intake would be associated with higher pregnancy-related weight change and glucose regulation biomarkers. The Pregnancy Eating Attributes Study recruited participants with uncomplicated singleton pregnancies ≤12 weeks gestation and no major chronic illness from 2 obstetrics clinics in the University of North Carolina at Chapel Hill Healthcare System from November 2014 to October 2016. Data from participants with completed pregnancy dietary recalls (n = 365) were analyzed. Intake (oz) of sugar-sweetened beverages (SSB) and non-nutritive sweetened beverages (NNSB) was calculated from 24-h dietary recalls across pregnancy and across postpartum. Weight was measured throughout pregnancy to 1-year postpartum to determine gestational weight gain adequacy and 1-year postpartum weight retention; fasting blood glucose and insulin were obtained in the 2nd trimester. Multinomial logistic regressions estimated associations of sweetened beverage intake with gestational weight gain adequacy; linear regressions estimated associations of sweetened beverage intake with postpartum weight retention, fasting blood glucose, and insulin. In analyses adjusted for age, household income-poverty ratio, education, marital status, and physical activity, neither SSB nor NNSB intake during pregnancy was associated with excessive gestational weight gain, postpartum weight retention, fasting glucose or fasting insulin. Additionally, SSB and NNSB intake in postpartum were unassociated with postpartum weight retention. Sweetened beverages may not contribute to excess pregnancy-related weight gain or glucose dysregulation within the moderate range of intake observed in this sample.

虽然含糖饮料的摄入量与一般人群的体重和血糖有关，但在怀孕期间的关系尚不清楚。这项前瞻性观察性研究验证了一个假设，即更多的含糖饮料摄入与更高的妊娠相关体重变化和葡萄糖调节生物标志物有关。妊娠饮食特征研究从2014年11月至2016年10月从北卡罗来纳大学教堂山医疗保健系统的2个产科诊所招募了妊娠≤12周且无重大慢性疾病的无并发症单胎妊娠的参与者。对完成妊娠饮食回忆的参与者（n = 365）的数据进行分析。含糖饮料（SSB）和无营养加糖饮料（NNSB）的摄入量（盎司）是根据怀孕和产后24小时的饮食回顾计算的。测量妊娠至产后1年的体重，以确定妊娠期体重增加是否充足和产后1年的体重保持；在妊娠中期测定空腹血糖和胰岛素。多项logistic回归估计含糖饮料摄入量与妊娠期体重增加充分性的关系；线性回归估计加糖饮料摄入与产后体重保持、空腹血糖和胰岛素的关系。在对年龄、家庭收入贫困率、教育程度、婚姻状况和身体活动进行调整的分析中，孕期摄入SSB和NNSB与妊娠期体重过度增加、产后体重保持、空腹血糖或空腹胰岛素无关。此外，产后摄入SSB和NNSB与产后体重保持无关。在本样本中观察到的适度摄入范围内，含糖饮料可能不会导致妊娠相关的过度体重增加或葡萄糖失调。

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引用次数: 0

Multimicronutrient and omega-3 fatty acid supplementation reduces low-grade inflammation in older participants: An exploratory study 补充多微量营养素和omega-3脂肪酸可减少老年参与者的低度炎症：一项探索性研究

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-19 DOI: 10.1016/j.nutres.2025.06.005

Felix Kerlikowsky , Karsten Krüger , Andreas Hahn , Jan Philipp Schuchardt

Aging is associated with chronic low-grade inflammation, while the status of anti-inflammatory (INFLA) micronutrients such as long-chain omega-3 fatty acids (n-3 PUFA), vitamin D, folate, and cobalamin is often low in older people. We hypothesized that n-3 PUFA and certain micronutrients reduce low-grade inflammation in older participants. To test this hypothesis the aim of this randomised, double-blinded, 12-week intervention study involving 112 healthy and physically active older participants (75.6 ± 3.9 years) was to investigate the effect of a multimicronutrient and n-3 PUFA supplementation in physiological doses (i.e., 400 µg folic acid, 100 µg cobalamin, 50 µg cholecalciferol, and 1000 mg eicosapentaenoic acid + docosahexaenoic acid per day) on INFLA biomarkers, which were aggregated in the INFLA score. Dietary intake data were converted into the energy-adjusted dietary inflammatory index (E-DII). A significant increase in the nutrient status biomarkers Omega-3 Index, serum 25-hydroxycholecalciferol, red blood cell folate, and holotranscobalamin was observed in the intervention group compared to the placebo group (all P < .001). In a multiadjusted model (age, sex, body mass index, E-DII, Omega-3 Index), the intervention significantly decreased the INFLA score compared to placebo (P = .036). Participants with a more pro-INFLA E-DII at baseline and higher age showed a greater decrease in the INFLA score than those with a more anti-INFLA E-DII (P = .028) and lower age (P = .043). An effect of multimicronutrient + n-3 PUFA supplementation seems to be more pronounced in older participants with higher age and those with a pro-INFLA background diet.

Trial registration: This study is officially recorded in the German Clinical Trials Register (DRKS00021302, registration date: 23.04.2020).

衰老与慢性低度炎症有关，而抗炎（INFLA）微量营养素如长链omega-3脂肪酸（n-3 PUFA）、维生素D、叶酸和钴胺素在老年人中通常较低。我们假设n-3 PUFA和某些微量营养素可以减少老年参与者的低度炎症。为了测试这个假说的目的随机,双盲,12周的干预研究涉及112名健康和体力活动老参与者(75.6±3.9岁)被调查的影响multimicronutrient和n - 3 PUFA的补充生理剂量(即400µg叶酸,100µg维生素b12, 50µg维生素d3,和1000毫克每天二十碳五烯酸+二十二碳六烯酸)INFLA生物标记,聚合在INFLA得分。将饮食摄入数据转换为能量调节饮食炎症指数（E-DII）。与安慰剂组相比，干预组的营养状态生物标志物Omega-3指数、血清25-羟基胆钙化醇、红细胞叶酸和全钴胺素显著增加(P <；措施)。在多因素调整模型（年龄、性别、体重指数、E-DII、Omega-3指数）中，与安慰剂相比，干预显著降低了INFLA评分（P = 0.036）。在基线时，E-DII水平较高且年龄较大的受试者，其INFLA评分的下降幅度大于抗E-DII水平较高的受试者（P = 0.028）和年龄较小的受试者（P = 0.043）。多微量营养素+ n-3 PUFA补充剂的效果似乎在年龄较大的老年参与者和具有促infla背景饮食的参与者中更为明显。试验注册：本研究已正式记录在德国临床试验注册（DRKS00021302，注册日期：23.04.2020）。

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引用次数: 0

Relationship of maternal high-fat diet to intestinal barrier integrity and disease in offspring 母体高脂饮食与子代肠道屏障完整性及疾病的关系

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-19 DOI: 10.1016/j.nutres.2025.06.003

Chen Zhang , Weiqi Zhong , Long Miao , Zhibing Lin , Shiqi Sun , Minmin Jiang , Cuiyuan Jin , Liyun Shi

High-fat diet (HFD) has been demonstrated to negatively affect the exacerbation of chronic diseases, such as obesity, diabetes, gastrointestinal disease, cardiovascular disease, and central nervous system disease. Research has revealed that maternal HFD affects the intestinal barrier integrity of offspring in multiple ways. Offspring not only “inherit” the abnormal gut microbiota induced by maternal HFD, thus having long-term effects on offspring health, but also are profoundly affected by various factors, such as the placental environment, mode of birth, and breast milk nutrition. In this review, we summarize recent epidemiological studies, clinical studies and animal experiments, and we evaluate the threat of maternal HFD to offspring health. We discuss the associations between maternal HFD and the intestinal barrier of offspring in the context of maternal-infant influence pathways, the gut microbiota and associated metabolism, intestinal physical barriers, and intestinal immune barriers. Further, we interpret the available evidence and its limitations. We believe that medical professionals and society must respond to the harmful effects of HFD to improve outcomes in the future.

高脂肪饮食（HFD）已被证明对慢性疾病（如肥胖、糖尿病、胃肠道疾病、心血管疾病和中枢神经系统疾病）的恶化有负面影响。研究表明，母体HFD通过多种方式影响后代肠道屏障的完整性。后代不仅“遗传”了母体HFD引起的肠道菌群异常，从而对后代健康产生长期影响，而且受到胎盘环境、出生方式、母乳营养等多种因素的深刻影响。本文综述了近年来的流行病学研究、临床研究和动物实验，并对母体HFD对后代健康的威胁进行了评价。我们在母婴影响途径、肠道微生物群和相关代谢、肠道物理屏障和肠道免疫屏障的背景下讨论了母体HFD与后代肠道屏障之间的关系。进一步，我们解释了现有的证据及其局限性。我们认为，医疗专业人员和社会必须对HFD的有害影响作出反应，以改善未来的结果。

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引用次数: 0

Higher serum carotenoid concentrations are associated with lower mortality in adults with advanced cardiovascular-kidney-metabolic syndrome 较高的血清类胡萝卜素浓度与晚期心血管-肾脏代谢综合征成人的较低死亡率相关

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-12 DOI: 10.1016/j.nutres.2025.06.002

Xiaoyun Li , Zhijuan Liao , Siyan Huo , Fangna Gu , Yong Yin , Xuanchu Ge

This study aimed to investigate the associations between serum carotenoid concentrations and all-cause mortality among adults with advanced cardiovascular-kidney-metabolic (CKM) syndrome. Data were analyzed from 1285 adults aged ≥20 years with advanced CKM syndrome (stages 3 or 4), identified from the National Health and Nutrition Examination Survey 2001 to 2006 cohort. Five serum carotenoids were assessed as exposures, including α-carotene, β-carotene, lycopene, lutein/zeaxanthin, and total carotenoids. Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% CIs, while quantile g-computation (Qgcomp) regression was employed to examine the joint effects of all carotenoids. During a median follow-up of 11.8 years, 936 (72.8%) deaths were recorded. Age- and sex-standardized all-cause mortality rates decreased across increasing quartiles of several serum carotenoids, most notably lycopene, for which the mortality rate declined from 106.6 (95% CI: 90.1-123.1) per 1000 person-years in the lowest quartile to 62.4 (95% CI: 54.6-70.1) in the highest quartile. Adjusted for potential confounders, higher concentrations of α-carotene (HR = 0.64, 95% CI: 0.49-0.84), β-carotene (HR = 0.76, 95% CI: 0.61-0.95), lutein/zeaxanthin (HR = 0.75, 95% CI: 0.59-0.96), lycopene (HR = 0.63, 95% CI: 0.49-0.81), and total carotenoids (HR = 0.81, 95% CI: 0.66-1.00) were significantly associated with lower all-cause mortality, while no significant association was observed for β-cryptoxanthin. Qgcomp regression demonstrated a significant joint protective effect of serum carotenoids on all-cause mortality (HR = 0.87, 95% CI: 0.79-0.95, P < .01), with lycopene contributing the most to the overall protective effect. In conclusion, the joint effect of serum carotenoids was independently associated with lower all-cause mortality in adults with advanced CKM syndrome, with lycopene showing the strongest contribution among the 5 carotenoids studied.

本研究旨在探讨成人晚期心血管-肾脏代谢综合征（CKM）患者血清类胡萝卜素浓度与全因死亡率之间的关系。数据分析了1285名年龄≥20岁的晚期CKM综合征（3期或4期）成人，这些数据来自2001年至2006年的国家健康与营养调查队列。五种血清类胡萝卜素被评估为暴露，包括α-胡萝卜素、β-胡萝卜素、番茄红素、叶黄素/玉米黄质和总类胡萝卜素。采用Cox比例风险回归模型估计风险比（hr）和95% ci，采用分位数g计算（Qgcomp）回归检验所有类胡萝卜素的联合效应。在中位11.8年的随访期间，记录了936例（72.8%）死亡。在几种血清类胡萝卜素含量增加的四分位数中，年龄和性别标准化的全因死亡率下降，最明显的是番茄红素，其死亡率从最低四分位数的每1000人年106.6 （95% CI: 90.1-123.1）下降到最高四分位数的每1000人年62.4 （95% CI: 54.6-70.1）。校正潜在混杂因素后，较高浓度的α-胡萝卜素（HR = 0.64, 95% CI: 0.49-0.84）、β-胡萝卜素（HR = 0.76, 95% CI: 0.61-0.95）、叶黄素/玉米黄质（HR = 0.75, 95% CI: 0.59-0.96）、番茄红素（HR = 0.63, 95% CI: 0.49-0.81）和总类胡萝卜素（HR = 0.81, 95% CI: 0.66-1.00）与较低的全因死亡率显著相关，而β-隐黄质则无显著相关性。Qgcomp回归显示血清类胡萝卜素对全因死亡率有显著的联合保护作用(HR = 0.87, 95% CI: 0.79-0.95, P <；.01)，其中番茄红素对整体保护作用的贡献最大。综上所述，血清类胡萝卜素的联合作用与晚期CKM综合征成人全因死亡率的降低独立相关，其中番茄红素在5种类胡萝卜素中贡献最大。

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引用次数: 0

Common Brazilian dietary pattern is associated with lower cardiovascular risk in adolescents 常见的巴西饮食模式与青少年较低的心血管风险相关

IF 3.1 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-11 DOI: 10.1016/j.nutres.2025.06.001

Maria Dinara de Araújo Nogueira , Xênia Maia Xenofonte Martins , Ribanna Aparecida Marques Braga , Isabelle Furtado Silva Cruz , Natassia Ellen Rodrigues Paiva Barros , Soraia Pinheiro Machado , Carla Soraya Costa Maia

Studies on dietary patterns in adolescents can contribute to monitoring and prevention of cardiovascular diseases. Our hypothesis is that, in Brazilian adolescents, the coffee with bread and Common Brazilian dietary patterns are associated with a better cardiovascular profile, since they have previously been associated with a lower chance of being overweight. This study aims to verify the association between dietary patterns and cardiovascular risk (CVR) in adolescents using isolated and combined lipid variables in the form of indices. This is a cross-sectional study conducted with 825 adolescents from public schools. The dependent variables included alterations in total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL-c), triglycerides, and non-HDL-c, as well as the Castelli I and II indices and the triglycerides/HDL-c ratio. Three dietary patterns were identified through principal component analysis: Coffee with bread, Common Brazilian, and Mixed. Regression models were used to assess the association of these patterns with isolated lipid alterations and indices. Greater adherence to the Common Brazilian pattern reduced the odds of having elevated total cholesterol by 49% (OR: 0.51; 95% confidence intervals [95% CI]: 0.28, 0.94), elevated low-density lipoprotein cholesterol by 70% (OR: 0.30; 95% CI: 0.12, 0.72), elevated non-HDL-c by 42% (OR: 0.58; 95% CI: 0.34, 0.98), even after adjustment for potential confounders. Greater adherence to the Common Brazilian pattern demonstrated a potential protective effect against CVR in adolescents. No associations were found between the Coffee with bread and Mixed patterns and CVR.

对青少年饮食模式的研究有助于监测和预防心血管疾病。我们的假设是，在巴西青少年中，咖啡加面包和常见的巴西饮食模式与更好的心血管状况有关，因为它们之前被认为与较低的超重几率有关。本研究旨在验证青少年饮食模式与心血管风险（CVR）之间的关系，采用单独和联合脂质变量的指数形式。这是一项对公立学校825名青少年进行的横断面研究。因变量包括总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇（HDL-c）、甘油三酯和非HDL-c、Castelli I和II指数以及甘油三酯/HDL-c比值的变化。通过主成分分析确定了三种饮食模式：咖啡加面包，普通巴西和混合。使用回归模型来评估这些模式与分离的脂质改变和指数的关联。即使在调整了潜在的混杂因素后，更严格地遵循巴西常见模式，总胆固醇升高的几率降低了49% (OR: 0.51； 95%可信区间[95% CI]: 0.28, 0.94)，低密度脂蛋白胆固醇升高的几率降低了70% (OR: 0.30; 95% CI: 0.12, 0.72)，非hdl -c升高的几率降低了42% （OR: 0.58; 95% CI: 0.34, 0.98）。在青少年中，更大程度地遵守共同巴西模式表明对CVR有潜在的保护作用。没有发现面包咖啡和混合模式与CVR之间的联系。

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引用次数: 0

Dietary inflammatory index as a modifiable risk factor for sarcopenia in adults with type 2 diabetes: A cross-sectional study 饮食炎症指数作为成人2型糖尿病患者肌肉减少症的可改变危险因素：一项横断面研究

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-06-04 DOI: 10.1016/j.nutres.2025.05.007

Serap Balaban Barta , Rıfat Bozkus , Hilal Simsek , Bengisu Kosal , Aslı Ucar

There is growing evidence that a proinflammatory diet contributes to the increased risk of sarcopenia by exacerbating low-grade inflammation and insulin resistance, ultimately inducing muscle loss in adults with type 2 diabetes. This study aimed to analyze the association of dietary inflammatory index (DII), physical activity level, and body composition with sarcopenia in adults with type 2 diabetes. The hypothesis of this study was that higher DII increases the risk of sarcopenia. This cross-sectional study was conducted with 249 adults aged 50 years and older with type 2 diabetes who were admitted to the Internal Medicine Department of a tertiary hospital in Türkiye. Nutritional status was determined by 24-hour recall, dietary inflammatory status by energy-adjusted-DII, and physical activity by the International Physical Activity Questionnaire-Short Form. Muscle strength was measured by handgrip dynamometer, body composition analysis was measured by bioelectrical impedance method, and sarcopenia was defined according to EWGSOP-2 criteria. The mean age of the participants was 62.1 ± 6.9 years and the prevalence of sarcopenia was 15.7%. Handgrip strength and appendicular skeletal muscle mass significantly decreased with increasing DII score from tertile 1 to 3 (P < .05). A higher DII score was an independent risk factor for sarcopenia (odds ratio = 2.36, 95% confidence interval: 1.25-4.47, P = .008). This study shows that increased DII was independently associated with sarcopenia in adults with type 2 diabetes after adjustment for potential confounders. Dietary strategies aimed at reducing the potential for inflammation through dietary patterns rich in antioxidants, fiber, and omega-3 fatty acids may be useful in managing the risk of sarcopenia in adults with type 2 diabetes aged 50 years and older.

越来越多的证据表明，促炎饮食通过加剧低度炎症和胰岛素抵抗，最终导致成人2型糖尿病患者肌肉损失，从而增加肌肉减少症的风险。本研究旨在分析成人2型糖尿病患者饮食炎症指数（DII）、身体活动水平和身体成分与肌肉减少症的关系。本研究的假设是较高的DII增加了肌肉减少症的风险。这项横断面研究对249名年龄在50岁及以上的2型糖尿病患者进行了研究，这些患者住进了日本一家三级医院的内科。营养状况通过24小时回忆来确定，饮食炎症状态通过能量调节- dii来确定，身体活动通过国际身体活动问卷-短表来确定。采用握力计测定肌力，采用生物电阻抗法测定体成分，根据EWGSOP-2标准定义肌肉减少症。参与者的平均年龄为62.1±6.9岁，肌肉减少症患病率为15.7%。从第1位到第3位，随着DII评分的增加，握力和尾骨骼肌质量显著降低(P <；. 05)。较高的DII评分是肌少症的独立危险因素（优势比= 2.36,95%可信区间：1.25-4.47,P = 0.008）。本研究表明，在排除潜在混杂因素后，成人2型糖尿病患者体内DII升高与肌肉减少症独立相关。旨在通过富含抗氧化剂、纤维和omega-3脂肪酸的饮食模式来降低炎症的可能性的饮食策略，可能有助于控制50岁及以上2型糖尿病患者肌肉减少症的风险。

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引用次数: 0

Editorial office and Board Members 编辑部和董事会成员

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-05-23 DOI: 10.1016/S0271-5317(25)00073-9

引用次数: 0

Diet quality of a population from a high-income gulf country in the era of transition: Kuwait as a model example 转型时代高收入海湾国家人口的饮食质量：以科威特为例。

IF 3.1 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Research

Pub Date : 2025-05-23 DOI: 10.1016/j.nutres.2025.05.003

Badreya Al-Lahou , Lynne M. Ausman , José L. Peñalvo , Gordon S. Huggins , Fang Fang Zhang

Diet is a modifiable risk factor for cardiovascular diseases (CVD). While the rate of CVD is escalating in Kuwait, studies examining dietary intake in the Kuwaiti population are scarce. This study aimed to evaluate the diet quality of a nationally representative sample of Kuwaiti adults using the first and only National Nutrition Survey. Dietary intake was assessed using a 24-hour dietary recall among 980 adults aged 20 years or older. Diet quality was evaluated using the American Heart Association (AHA) diet score. Intake and scores of the AHA components were analyzed for the total sample and stratified by age and sex using complex survey regression models adjusted for sampling weights. The mean AHA diet score (maximum 80) was 42.5 ± 0.46. Over 70% of adults consumed insufficient amounts of fruits/vegetables, whole grains, fish/shellfish, and nuts/seeds/legumes, while nearly 80% exceeded saturated fat limits and over 95% exceeded sodium recommendations. Diet quality scores increased significantly with age (P < .0001), with older adults (≥60 years, score = 49.4) scoring notably higher than younger adults (<30 years, score = 37.4). Younger adults had particularly low intake of fruits, vegetables, whole grains, and fish, while no differences were observed for sodium or nuts/seeds/legumes. Overall diet quality did not differ significantly by sex. Suboptimal diet quality was prevalent, particularly among younger adults in Kuwait. This study underscores the urgent need for targeted dietary improvements and establishes a crucial reference point for future public health initiatives.

饮食是心血管疾病（CVD）的可改变危险因素。虽然科威特心血管疾病的发病率正在上升，但对科威特人口饮食摄入量的研究却很少。本研究旨在利用第一次也是唯一一次全国营养调查来评估科威特成年人的全国代表性样本的饮食质量。对980名年龄在20岁或以上的成年人进行24小时饮食回顾，评估他们的饮食摄入量。饮食质量采用美国心脏协会（AHA）饮食评分进行评估。对总样本的摄入和AHA成分得分进行分析，并使用调整了抽样权重的复杂调查回归模型按年龄和性别分层。平均AHA饮食评分（最高80分）为42.5±0.46。超过70%的成年人摄入的水果/蔬菜、全谷物、鱼类/贝类和坚果/种子/豆类不足，近80%超过饱和脂肪限制，超过95%超过钠建议摄入量。饮食质量评分随年龄的增长而显著升高（P < 0.0001），老年人（≥60岁，评分= 49.4）得分显著高于年轻人(

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引用次数: 0