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[Atherogenic Plasma indices and their association with cardiovascular risk in postmenopausal women: A population-based study]. [绝经后妇女动脉粥样硬化血浆指数及其与心血管风险的关系:一项基于人群的研究]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05738
Marcela Sepúlveda González, Samuel Durán-Aguero, Lincoyán Fernández-Huerta, Carla Guzmán Pincheira

Introduction: Introduction: Menopause represents a critical stage of aging, marked by a decrease in estradiol and progesterone, which contributes to vascular dysfunction, increased blood pressure, accumulation of abdominal fat and hyperlipidemia, resembling the cardiovascular profile of older men. Objective: This study analyzes the relationship between plasma atherogenic indices and cardiovascular risk according to the postmenopausal phase in Chilean women. Methods: A secondary analysis of the National Health Survey 2016-2017 was performed, including women between 40 and 70 years in early or late menopause, classified according to Stages of Reproductive Aging Workshop (STRAW). Lipid profile was analyzed and atherogenic indices were calculated. T-tests, Mann-Whitney and Chi-square tests were applied, considering significance at p<0.05. Results: The sample included 742 menopausal women; 74.4% presented excess malnutrition and 88% abdominal obesity, with an average Body Mass Index (BMI) of 30 kg/m² in both groups. Systolic blood pressure was 8 points higher in late menopause. The atherogenic indices showed significant differences in both stages, with the plasma atherogenic index having the highest correlation. Conclusion: The plasma atherogenic index and the atherogenic coefficient are cost-effective tools for assessing cardiovascular risk in this population.

更年期是衰老的关键阶段,以雌二醇和黄体酮的减少为标志,导致血管功能障碍、血压升高、腹部脂肪堆积和高脂血症,类似于老年男性的心血管特征。目的:分析智利绝经后妇女血浆动脉粥样硬化指标与心血管危险的关系。方法:对2016-2017年全国健康调查进行二次分析,纳入40 ~ 70岁绝经早期或晚期的女性,根据生殖衰老阶段研讨会(STRAW)进行分类。分析脂质谱,计算动脉粥样硬化指数。采用t检验、Mann-Whitney检验和卡方检验,考虑结果的显著性:样本包括742名绝经妇女;74.4%的人表现为过度营养不良,88%的人表现为腹部肥胖,两组平均体重指数(BMI)均为30 kg/m²。绝经后期的收缩压要高出8个点。两期动脉粥样硬化指数均有显著性差异,其中血浆动脉粥样硬化指数相关性最高。结论:血浆动脉粥样硬化指数和动脉粥样硬化系数是评估该人群心血管风险的有效工具。
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引用次数: 0
[Evaluation of the diagnostic performance of the STRONGkids tool]. 【STRONGkids工具的诊断性能评价】。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05717
Laura Cristina Sánchez Giraldo, Jennifer Tatiana Mappe-Rojas, Olga Lucía Pinzón-Espitia, Jairo Echeverry-Raad

Introduction: Introduction: the prevalence of malnutrition in the pediatric hospital population ranges between 6 and 50 % in different countries. It is necessary to quantify the prevalence of risk or malnutrition at hospital admission in Colombia. Objective: to estimate the prevalence of intrahospital nutritional status using standardized reference standards and to perform the operational diagnostic by evaluating assessment of malnutrition of the STRONGkids tool in children hospitalized in a highly complex healthcare institution. Materials and methods: a descriptive cross-sectional study was carried out in which pediatric patients were selected consecutively for 5 weeks. The population would correspond to 300 patients. Results: the prevalence of some degree of hospital malnutrition was 3.5 % (95 % CI, 0.3-11) in children under 5 years of age and 3.8 % (95 % CI, 0.8-10.6) in older children. The STRONGkids tool, with a high risk classification, showed an average sensitivity of 81 % (95 % CI, 40 %-100 %), and average specificity of 97.9 % (95 % CI, 94.5 %-100 %) in the diagnosis of Malnutrition, according to the anthropometric criteria of Resolution 2465 of 2016 of the Ministry of Health. Conclusion: STRONGkids is a valid tool in the diagnosis of any type of hospital malnutrition in children.

在不同的国家,儿科医院人口中营养不良的发生率在6%到50%之间。有必要量化哥伦比亚住院时风险或营养不良的普遍程度。目的:利用标准化参考标准估计院内营养状况的流行程度,并通过评估STRONGkids工具对一家高度复杂的医疗机构住院儿童营养不良的评估,进行可操作性诊断。材料与方法:采用描述性横断面研究,选取连续5周的儿科患者。人口相当于300个病人。结果:5岁以下儿童不同程度的医院营养不良发生率为3.5% (95% CI, 0.3 ~ 11),较大儿童为3.8% (95% CI, 0.8 ~ 10.6)。根据卫生部2016年第2465号决议人体测量标准,STRONGkids工具具有高风险分类,诊断营养不良的平均敏感性为81% (95% CI, 40% - 100%),平均特异性为97.9% (95% CI, 94.5% - 100%)。结论:STRONGkids是诊断各类医院儿童营养不良的有效工具。
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引用次数: 0
Importance of the genetic map of non-alcoholic fatty liver disease (NALFD). 非酒精性脂肪肝(NALFD)遗传图谱的重要性
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.06028
Patricia Quadros Dos Santos, Helma Pinchemel Cotrim, Carla Daltro, Raquel Rocha

Introduction:

作品简介:
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引用次数: 0
[A comparison of different generalized models to study the factors associated with body mass index and circumference in Colombian adults]. [研究哥伦比亚成年人身体质量指数和围度相关因素的不同广义模型的比较]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05600
Javier Martínez Torres, Karen Julieth Quintero Díaz, Óscar Alexánder Gutiérrez-Lesmes, Claudia Milena Barrera Rangel, Jorge Iván Anaya Baldovino

Introduction: Introduction: the adiposity excess has become a public health problem; therefore, many authors have studied this phenomenon from different standpoints. However, studies that have evaluated adiposity indicators sometimes do not report the assessment of model assumptions, which may have introduced potential bias in the interpretations. Objective: to compare the metrics of generalized models to estimate factors associated with body mass index and waist circumference in Colombian adults for the year 2015. Methodology: it was an analytical cross-sectional study. A sample of 72,815 adults (aged 18 to 65 years) was considered. Weight, height, and waist circumference were measured, with the first two used to calculate BMI. To estimate the association, five regression models were developed for each marker. The model fit was assessed using GAIC, and residuals were checked using worm-plot graphs. Results: for both adiposity markers, the generalized additive models for location, scale, and shape model showed the best fit according to GAIC and the worm-plot graph. Conclusions: the use of generalized additive models for location, scale, and shape for studying body mass index and waist circumference provides better model fit and more effectively meets underlying assumptions. The estimator magnitudes across models maintain the same directionality; however, their magnitudes show significant variations.

肥胖过剩已成为一个公共卫生问题;因此,许多作者从不同的角度研究了这一现象。然而,评估肥胖指标的研究有时没有报告对模型假设的评估,这可能会在解释中引入潜在的偏差。目的:比较2015年哥伦比亚成年人体重指数和腰围相关因素的广义模型指标。研究方法:采用分析性横断面研究。72,815名成年人(年龄在18至65岁之间)被纳入研究范围。测量了体重、身高和腰围,前两者用于计算BMI。为了估计相关性,对每个标记开发了五个回归模型。使用gac评估模型拟合,并用虫图检查残差。结果:对于两种肥胖标志物,根据gac和蠕虫图,位置、尺度和形状模型的广义加性模型拟合最佳。结论:使用位置、尺度和形状的广义加性模型来研究体重指数和腰围可以提供更好的模型拟合,更有效地满足潜在的假设。跨模型的估计量值保持相同的方向性;然而,它们的大小显示出显著的变化。
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引用次数: 0
[Albumin-myoestatosis gauge assisted by an artificial intelligence tool as a prognostic factor in patients with metastatic colorectal-cancer]. [人工智能工具辅助的白蛋白-肌定型仪作为转移性结直肠癌患者的预后因素]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05687
Daniel de Luis, David Primo, Olatz Izaola, Israel Sánchez Lite, Juan José López Gómez

Introduction: Objectives: to evaluate the prognostic role of the marker albumin-myosteatosis (MAM) in Caucasian patients with metastatic colorectal cancer. Material and methods: this study involved 55 consecutive Caucasian patients diagnosed with metastatic colorectal cancer. CT scans at the L3 vertebral level were analyzed to determine skeletal muscle cross-sectional area, skeletal muscle index (SMI), and skeletal muscle density (SMD). Bioelectrical impedance analysis (BIA) (phase angle, reactance, resistance, and SMI-BIA) was used. Albumin and prealbumin were measured. The albumin-myosteatosis marker (AMM = serum albumin (g/dL) × skeletal muscle density (SMD) in Hounsfield units (HU) was calculated. Survival was estimated using the Kaplan-Meier method and comparisons between groups were performed using the log-rank test. Results: the median age was 68.1 ± 9.1 years. Patients were divided into two groups based on the median MAM (129.1 AU for women and 156.3 AU for men). Patients in the low MAM group had significantly reduced values of phase angle and reactance, as well as older age. These patients also had higher rates of malnutrition by GLIM criteria (odds ratio: 3.8; 95 % CI = 1.2-12.9), low muscle mass diagnosed with TC (odds ratio: 3.6; 95 % CI = 1.2-10.9) and mortality (odds ratio: 9.82; 95 % CI = 1.2-10.9). The Kaplan-Meir analysis demonstrated significant differences in 5-year survival between MAM groups (patients in the low median MAM group vs. patients in the high median MAM group), (HR: 6.2; 95 % CI = 1.10-37.5). Conclusion: the marker albumin-myosteatosis (MAM) may function as a prognostic marker of survival in Caucasian patients with metastatic CRC.

目的:探讨白蛋白-肌骨增生症(MAM)在高加索转移性结直肠癌患者预后中的作用。材料和方法:本研究纳入55例连续诊断为转移性结直肠癌的高加索患者。分析L3椎体水平的CT扫描以确定骨骼肌横截面积、骨骼肌指数(SMI)和骨骼肌密度(SMD)。采用生物电阻抗分析(BIA)(相角、电抗、电阻和SMI-BIA)。测定白蛋白和前白蛋白。计算Hounsfield单位(HU)白蛋白-肌骨化标志物(AMM =血清白蛋白(g/dL) ×骨骼肌密度(SMD))。生存率采用Kaplan-Meier法估计,组间比较采用log-rank检验。结果:中位年龄为68.1±9.1岁。根据中位MAM(女性129.1 AU,男性156.3 AU)将患者分为两组。低MAM组患者的相角和电抗值明显降低,且年龄较大。根据GLIM标准,这些患者也有更高的营养不良率(优势比:3.8;95% CI = 1.2-12.9),低肌肉量诊断为TC(优势比:3.6;95% CI = 1.2-10.9)和死亡率(优势比:9.82;95% ci = 1.2-10.9)。Kaplan-Meir分析显示,MAM组(低中位MAM组患者与高中位MAM组患者)的5年生存率存在显著差异(HR: 6.2;95% ci = 1.10-37.5)。结论:白蛋白-肌骨增生症(MAM)标记物可能作为转移性结直肠癌高加索患者生存的预后标记物。
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引用次数: 0
Efficacy of cookies made from iron-fortified cassava composite flour in adolescent girls. 由铁强化木薯复合面粉制成的饼干对青春期女孩的功效。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05735
Sri Anna Marliyati, Slamet Budijanto, Feri Kusnandar, Rokhani Hasbullah, Azroo Alfaqih Rojuli, Mutiara Putri Abiyoga

Introduction: Introduction: anaemia among adolescent girls remains quite high. According to data from the WHO, the global prevalence of anaemia ranges from 40 % to 88 %. In Indonesia, the prevalence of anaemia among those aged 5-14 years is 26.8 %, and 32 % among those aged 15-24 years. Anaemia is a medical condition in which haemoglobin levels are below normal. This condition may be caused by low iron intake or impaired iron absorption. The purpose of this study is to evaluate the efficacy of an intervention using iron-fortified cassava composite flour cookies for adolescent girls with anaemia. Methods: the research design used a single-blind pre-post study conducted on adolescent girls in an Islamic boarding school, divided into control and intervention groups. It was carried out randomly on subjects per group 28, with a total of 56 subjects in the study. Results were obtained in a total of 43 subjects, 27 in the intervention group and 16 in the control group. The intervention was carried out for three months, with cookies provided once a week for consumption over a week. Subject characteristics and dietary patterns were obtained through a questionnaire. Haemoglobin levels and anthropometric measurements were obtained through direct measurements. Cookie consumption compliance was assessed based on a compliance form. Results: there was a significant increase in in Z-score in both groups. The average haemoglobin level increased from baseline to middle line, with a significant difference observed in both groups (p < 0.05), but no significant difference between the groups (p < 0.05). All the macronutrient adequacy levels for most subjects were classified as severely deficient. The frequency of food intake across all food groups was generally low for all subjects. Cookies consumption compliance at middle line was significantly higher in the control group. Conclusion: the ANCOVA test for haemoglobin levels indicated no significant difference between the groups. Covariate variables that influenced changes in haemoglobin levels were the percentage of cookie consumption compliance and baseline haemoglobin levels.

导言:少女的贫血率仍然很高。根据世界卫生组织的数据,全球贫血患病率在40%至88%之间。在印度尼西亚,5-14岁儿童的贫血患病率为26.8%,15-24岁儿童的贫血患病率为32%。贫血是一种血红蛋白水平低于正常水平的疾病。这种情况可能是由铁摄入量低或铁吸收受损引起的。本研究的目的是评估使用铁强化木薯复合面粉饼干对患有贫血的青春期女孩的干预效果。方法:本研究采用单盲法对一所伊斯兰寄宿学校的青春期女生进行前后研究,分为对照组和干预组。这项研究是随机进行的,每组28人,总共有56人参加了这项研究。结果共43例,干预组27例,对照组16例。干预进行了三个月,每周提供一次饼干,供一周食用。通过问卷调查获得受试者特征和饮食模式。血红蛋白水平和人体测量值通过直接测量获得。根据遵守表格评估饼干消费的遵守情况。结果:两组患者Z-score均有显著升高。平均血红蛋白水平从基线到中线升高,两组间差异有统计学意义(p < 0.05),两组间差异无统计学意义(p < 0.05)。大多数受试者的所有宏量营养素充足水平都被归类为严重缺乏。在所有食物组中,所有受试者的食物摄入频率普遍较低。对照组中线饼干消费依从性显著高于对照组。结论:ANCOVA检测血红蛋白水平各组间无显著差异。影响血红蛋白水平变化的协变量是饼干食用依从性的百分比和基线血红蛋白水平。
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引用次数: 0
[Editor's corner. 2025 balance sheet]. (编辑的角落。2025年资产负债表]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.06576
José Manuel Moreno Villares, Gabriel Olveira

Introduction:

作品简介:
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引用次数: 0
[Beyond the biopsychosocial model: critique and integrative proposal for the study of eating behavior]. [超越生物心理社会模型:对饮食行为研究的批评和综合建议]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05964
Sergio Vladimir Flores-Carrasco, Ángel Roco-Videla, Román Montaña-Ramírez

Introduction:

作品简介:
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引用次数: 0
[Clarifying aspects of mixed factorial analysis in research with repeated measures]. [阐明重复测量研究中混合析因分析的各个方面]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.06067
Román Montaña Ramírez, Ana Nieves-Maríñez

Introduction:

作品简介:
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引用次数: 0
[Body composition analysis on computed tomography scans using easy-to-access segmentation software]. [使用易于访问的分割软件对计算机断层扫描进行身体成分分析]。
IF 1.1 4区 医学 Q3 BUSINESS Pub Date : 2026-02-27 DOI: 10.20960/nh.05699
Andrés Jiménez-Sánchez, Pedro Pablo García-Luna

Introduction: Computed tomography (CT) is an indirect and reference technique for body composition analysis with interesting possibilities in clinical nutrition. Segmentation is the automatic or semi-automatic software-based process by which different metabolic tissues of interest (muscle tissue, subcutaneous adipose tissue, visceral adipose tissue and intermuscular adipose tissue) that are part of the current diagnoses of malnutrition, sarcopenia and sarcopenic obesity are delimited, separated and quantified. The Alberta protocol is the most common segmentation guide, being applicable in most software. In this paper, we review the main characteristics of the most common open-source segmentation software, their degree of agreement, and some precautions and limitations of this process.

计算机断层扫描(CT)是人体成分分析的一种直接和参考技术,在临床营养学中具有有趣的可能性。分割是一种自动或半自动的基于软件的过程,通过该过程,对目前诊断营养不良、肌肉减少症和肌肉减少性肥胖的不同代谢组织(肌肉组织、皮下脂肪组织、内脏脂肪组织和肌间脂肪组织)进行划分、分离和量化。Alberta协议是最常用的分段指南,适用于大多数软件。在本文中,我们回顾了最常见的开源分割软件的主要特点,他们的一致性程度,以及在这个过程中的一些注意事项和局限性。
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引用次数: 0
期刊
Nutricion hospitalaria
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