Nutricion hospitalaria最新文献

Introduction:

Introduction: IIntroduction: patients with amyotrophic lateral sclerosis (ALS) require nutritional support, in most cases with enteral nutrition through gastrostomy, either endoscopic (PEG) or radiological (PRG). Objectives: to analyze the characteristics of patients with ALS at the time of PEG/PRG placement, and to compare the efficacy and safety of PRG versus PEG. Methods: a retrospective descriptive study. All patients with ALS who required gastrostomy in the last 3 years (2021-2023) in our hospital were recruited (4 PEG and 6 PRG). Demographic and nutritional parameters were analyzed. Results: ten patients were included, with an average age of 57 years. All patients presented with dysphagia and received oral or tube supplements prior to gastrostomy placement. The average duration of enteral nutrition was approximately 50 months, with a mortality rate of 30 % at 12 months after gastrostomy. The success rate of PEG and PRG was similar, with no complications. All patients developed deterioration of respiratory function, even after nutritional support. Conclusion: gastrostomy should be indicated as soon as a patient is at risk of aspiration pneumonia or when weight loss begins. Although the nutritional benefit of gastrostomy is well established, there is currently a delay between diagnosis and placement of approximately 4 years. PRG appears to be safer than PEG in patients with ALS and respiratory failure.

Introduction: Introduction: depression is more frequent among people with obesity (PwO) compared to the general population. Depression seems to improve after bariatric surgery (BS) at short term, but data are inconclusive at long term. Besides, it is not known whether depressive symptoms among PwO are similar to those people with a major depression without obesity. Objectives: we aimed to study whether there are differences regarding depressive symptomatology among subjects seeking BS or patients after BS in the long-term compared with subjects with MDD. Methods: the Beck Depression Inventory (BDI) was administered to three groups: 52 patients seeking BS (OB), 135 patients with a BS with a minimum follow-up of 18 months (BS) and 45 subjects with a MDD (MDD). Results: the MDD obtained the higher score with the BDI whether compared to the OB (18.9 ± 12.7 vs 14.2 ± 6.9; p = 0.01) or the BS (18.9 ± 12.7 vs 8.1 ± 8; p < 0.0001). Also, BS presented a lower BDI than the OB (8.1 ± 8 vs 14.2 ± 6.9; p < 0.0001). The MDD scored higher in the psychological domain than patients in the OB (9.9 ± 7.5 vs 5.7 ± 5.1; p < 0.0001) as well as in the BS (9.9 ± 7.5 vs 3.1 ± 3; p < 0.0001). There was a negative correlation between a greater score in the somatic domain and %EPP (p = 0.04). Conclusions: at long term, depressive symptomatology among subjects with a BS remained lower compared to PwO seeking BS.PwO presented a different cluster of depression compared to individuals with a MDD. BS reduces the somatic depressive cluster at long term, although its presence is associated to a lesser weight loss.

Introduction: Background: metabolic syndrome (MetS) is a group of clinical anomalies that share an inflammatory component of multifactorial etiology. Objectives: the present study aims to relate the genetic variant (rs61330082 C/T) with dietary patterns in the presence of MetS and the application of molecular docking according to the genotype and associated transcription factors. Methods: 197 individuals aged 18 to 65 were included, from whom anthropometric measurements were taken, and a blood sample from the forearm. DNA extraction and enzymatic digestion were performed to determine the genotype of each participant by PCR-RFLP. Dietary patterns were analyzed using a nutritional questionnaire validated for the Mexican population. Serum levels of the protein visfatin were assessed by ELISA. Finally, bioinformatics tools were used for molecular docking to infer the binding of transcriptional factors in the polymorphic region. Results: the TT genotype was present in only 10 % of the population. Women carrying the CT+TT genotype, according to the dominant genetic model, had higher serum levels of triglycerides and VDLD-C. Statistical analysis did not show a significant association between the presence of MetS and the dominant CT+TT model (OR = 1.41, 95 % CI = 0.61-3.44, p = 0.53). We identified PAX5 as a transcription factor binding to the polymorphic site of this genetic variant. Conclusions: this study demonstrated a significant association between the genetic variant (rs61330082 C/T) and lipid parameters. Women carrying the T allele have a higher risk of high triglyceride levels, a criterion for metabolic syndrome.

Introduction: Introduction: surveys play a crucial role in evaluating the quality of food in populations, especially in healthcare settings, helping identify important characteristics of food descriptions and improving efficiency in the collection and management of data in dietary surveys. Objective: the primary aim of this study was to analyze the internal consistency of the New Index of Global Food Quality (NIGFQ) instrument and assess its applicability to sociodemographic variables and levels of physical activity (IPAQ-S) in a specific region of Chile. Methods: a descriptive, comparative, and correlational study that utilizes the online platform of Google Forms for data collection using the New Index of Global Food Quality (NIGFQ) and IPAQ-S instruments, in addition to considering sociodemographic variables, in a sample of 1,331 participants from the metropolitan region of Chile. Results: the study shows an improvement in the reliability of the NIGFQ (Cronbach's alpha: 0.63 to 0.71). Findings reveal significant inverse correlations between fruits (r = -0.31; p ≤ 0.05) and legumes (r = -0.34; p ≤ 0.05) with body mass. Conclusions: it is concluded that values above 52.5 points are considered healthy on the new evaluation scale of the index, supported by statistical reliability tests. Similarly, the components of the adjusted New Index of Global Food Quality, particularly fruits and vegetables in greater proportion, show a beneficial relationship with daily consumption in reducing body mass index and body weight.

Introduction: Background and aims: omentin-1 might present a potential role in metabolic syndrome (MS). The aim of our investigation was to evaluate the relationship between omentin-1 and nascent MS. Methods: we carried out a cross-sectional study in 606 obese subjects. Adiposity parameters, blood pressure, fasting blood glucose, insulin levels, insulin resistance (HOMA-IR), triglyceride and glucose index (TyG), lipid profile, C-reactive protein, omentin-1, and prevalence of nascent MS were determined. Results: 307 subjects had MS (49.2 %) and 299 did not show MS (50.8 %). Subjects without MS have higher omentin-1 levels (delta: 78.0 ± 13.8 ng/ml; p = 0.01). A negative correlation was observed between omentin-1 and adiposity parameters, glucose, insulin, HOMA-IR, TyG index and triglycerides in both groups. And a positive correlation was observed with HDL-cholesterol. BMI (OR = 1.17, 95 % CI = 1.09-1.31; p = 0.02), HOMA-IR (OR = 5.21, 95 % CI = 1.69-21.11; p = 0.01) and omentin-1 (OR = 0.95, 95 % CI = 0.94-0.97; p = 0.02) remained in the final model as predictors of MS. The cut-off point according to the Youden index was 372.45 ng/ml of omentin-1, to predict MS. Conclusions: Caucasian patients with obesity had clearly lower serum omentin-1 levels in the presence of nascent MS. An inverse correlation was demonstrated with adiposity parameters, insulin resistance and triglycerides. And a direct correlation with HDL-cholesterol was reported.

Introduction:

Introduction: Introduction: sports nutrition and supplementation (SD) are commonly used by road and mountain runners to achieve their goals and increased performance. However, sometimes sports practice can become an obsession and/or addiction, although the literature on the use of DS and sports addiction (SD) is scarce. Objective: to describe and analyse the relationship between SD use and AD in asphalt and mountain runners in the Canary Islands. Methodology: a cross-sectional observational study in a sample of 613 adult athletes, using a self-administered online questionnaire that assessed SD use and AD, disseminated by federations, sports clubs, race organisers and social networks. Results: 75.7 % of participants reported taking some form of SD and being younger was associated with a higher likelihood of taking SD. On the total SD scale (SAS-15) the mean was 9.19 (SD = 3.24), above the midpoint of the theoretical range (0-15). Among participants taking and not taking DS, there is higher AD in those taking versus those not; and among those taking DS, AD is significantly higher in those taking weight management recoverers and supplements. Conclusions: the sample had indicators of WD and, for the most part, were consuming some form of DS. In addition, there is a significant relationship between the use of DS and WD in road and mountain runners, with the level of WD being a predictor of DS consumption.

Introduction: Introduction: the Global Leadership Initiative on Malnutrition (GLIM) was created to unify the diagnosis of malnutrition worldwide. The main objective of this work is to evaluate the validity of the GLIM criteria for diagnosing malnutrition in a population over 65 years of age living in a nursing home. In addition, the order of importance of the GLIM criteria for diagnosing malnutrition was also analyzed. Material and methods: a cross-sectional study was carried out with 130 older adults institutionalized in a nursing home. To study the validity of the GLIM criteria, sensitivity and specificity were calculated and a Receiver Operating Characteristic (ROC) curve was calculated using the MNA questionnaire as the reference diagnostic method. A Lasso regression model was used to determine the order of importance of the criteria. Results: according to GLIM and MNA the prevalence of malnutrition was 26.2 % and 18.5 %, respectively. The GLIM criteria were found to have a sensitivity of 100 %, a specificity of 91 % and a very good level of precision (AUC = 0.95). The order of importance of the criteria from highest to lowest are loss of muscle mass, weight loss, presence of inflammation, low BMI and decreased nutrient intake or assimilation. Conclusions: the GLIM criteria presented a satisfactory level of validity and are therefore an acceptable method to diagnose malnutrition in institutionalized older adults.

Introduction: Introduction: water is a crucial component of human health useful for various bodily functions. Despite its importance, previous research has largely overlooked hydration in Latin America, focusing instead on regions with greater access to a variety of food sources. Objective: hence, this study provides comprehensive data on water consumption patterns in this region and analyses the hydration profiles of urban Latin American populations, emphasizing the role of pure water in daily intake. Materials and methods: involving 5977 participants from Argentina, Brazil, Costa Rica, Ecuador, and Peru, the study utilized a cross-sectional approach, examining total water intake (TWI) through two nonconsecutive 24-hour dietary recalls. This study focused on understanding the contribution of pure water to daily hydration and identifying disparities in water consumption patterns across different demographic conditions by measuring the TWI from beverages. Results: the findings indicated significant variations in hydration profiles based on country, sex, and socioeconomic status. The median TWI was 3245.6 g/day, with a median water intake from beverages of 1982.9 g/d kcal, which represented 61 % of the participants' total water intake. A total of 63.8 % of the overall sample met the TWI recommendations. Our data indicate that 38.4 % of the water intake came from plain water, followed by coffee and tea (16.9 %), commercial sugar-sweetened beverages (13.7 %), and homemade SSB (11.7 %). Conclusion: these findings contribute to a deeper understanding of nutritional behaviors and may serve as a basis for future studies and health interventions focused on improving hydration habits, with emphasis on pure water consumption, especially in urban areas in developing regions.