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Associations between body mass index and episodic memory for recent eating, mindful eating, and cognitive distraction: A cross-sectional study. 体重指数与最近进食的外显记忆、用心进食和认知分心之间的关系:一项横断面研究。
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-01-04 eCollection Date: 2024-02-01 DOI: 10.1002/osp4.728
Elanor C Hinton, Victoria Beesley, Sam D Leary, Danielle Ferriday

Objectives: Eating while distracted has been associated with a higher body mass index (BMI), whereas mindful eating and episodic memory for recent eating have shown the opposite pattern. This pre-registered, global study (https://osf.io/rdjzk) compared the relative association between these variables (and four "positive controls": restraint, disinhibition, emotional eating, plate clearing) and self-reported BMI. The timing of data collection (April-May 2020) during the SARS-CoV-2 pandemic enabled an investigation of the impact of stay-at-home restrictions imposed on the UK population on the measures of eating behavior.

Methods: An online survey was completed, including: (i) demographic data (e.g., self-reported BMI), (ii) Likert ratings assessing episodic memory for recent eating, mindful eating, cognitive distraction, restrained eating, emotional eating, disinhibition and plate clearing over the last 12 months and the last 7 days (during the first UK COVID-19 lockdown), and (iii) the Mindful Eating Questionnaire (MEQ).

Results: A large adult sample participated (N = 846; mean (SD) age = 33.0 (14.3) years; mean (SD) BMI = 24.6 (5.6) kg/m2). Mindful eating (MEQ-total score) was associated with a lower self-reported BMI (β = -0.12; 95% CI = -0.20, -0.04; p = 0.004), whereas disinhibited eating was associated with a higher self-reported BMI (β = 0.30; 95% CI = 0.21, 0.38; p < 0.001). In UK participants (n = 520), consistent changes in eating behavior during lockdown were not found. For those that did experience change, decreases were reported in; emotional eating, disinhibited eating, focusing on taste during a meal (a measure of mindful eating), and using a smart phone while eating.

Conclusions: These findings provide evidence in a large global sample for associations between BMI and (i) mindful eating, and (ii) disinhibited eating. Future research should evaluate whether mindful eating demonstrates a prospective association with body weight and should consider mechanisms of action.

目的:注意力分散时进食与体重指数(BMI)升高有关,而用心进食和对近期进食的外显记忆则显示出相反的模式。这项预先注册的全球性研究(https://osf.io/rdjzk)比较了这些变量(以及四种 "积极对照":克制、抑制、情绪化进食和清盘)与自我报告的体重指数之间的相对关联。数据收集的时间(2020 年 4 月至 5 月)正值 SARS-CoV-2 大流行期间,因此可以调查英国人在家限制饮食对饮食行为测量的影响:完成了一项在线调查,内容包括:(i) 人口统计学数据(如自我报告的体重指数);(ii) 对过去 12 个月和过去 7 天(英国 COVID-19 第一次封锁期间)最近进食的历时记忆、正念进食、认知分心、克制进食、情绪化进食、抑制和清盘进行评估的李克特评分;(iii) 正念进食问卷 (MEQ):大量成人样本参与了调查(N = 846;平均(标清)年龄 = 33.0 (14.3) 岁;平均(标清)体重指数 = 24.6 (5.6) kg/m2)。注意饮食(MEQ-总分)与自我报告的体重指数较低有关(β = -0.12;95% CI = -0.20,-0.04;p = 0.004),而抑制性饮食与自我报告的体重指数较高有关(β = 0.30;95% CI = 0.21,0.38;p n = 520),但在封锁期间未发现饮食行为的一致变化。对于那些确实发生了变化的人,据报告在以下方面有所减少:情绪化进食、抑制性进食、进餐时专注于味道(用心进食的一种测量方法)以及进食时使用智能手机:这些研究结果在一个大型全球样本中证明了体重指数(BMI)与(i)正念进食和(ii)抑制性进食之间的联系。未来的研究应评估正念进食是否与体重有前瞻性关联,并应考虑其作用机制。
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引用次数: 0
The individual-level effects of social media campaigns related to healthy eating, physical activity, and healthy weight: A narrative review. 与健康饮食、体育锻炼和健康体重相关的社交媒体活动在个人层面的影响:叙述性综述。
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-01-04 eCollection Date: 2024-02-01 DOI: 10.1002/osp4.731
Yajing Luo, Ana G Maafs-Rodríguez, Daniel P Hatfield

Objective: Social media are promising channels for health communication promoting positive weight-related behaviors, but no prior studies have synthesized evidence on the independent effects of social media campaigns focused on promoting healthy eating, physical activity (PA), and healthy weight. This study aimed to fill that gap and inform future social media-based obesity-prevention research and practice by reviewing findings from studies testing the effects of such campaigns on individual-level cognitive, behavioral, and anthropometric outcomes.

Method: The Web of Science and PubMed databases were searched for peer-reviewed articles published between 2012 and 2023 that explored the independent effects of social media campaigns related to healthy eating, PA, or weight management. Study characteristics and outcomes were extracted and summarized.

Results: Eleven studies were included in this review describing campaigns targeting healthy eating-related outcomes (e.g., fruit and vegetable consumption, meal preparation, nutrition label reading), PA, or weight management. Most campaigns (n = 7) were developed by universities or research centers. Priority audiences included parents, adult females, adolescents, college students, and adult government employees. The majority (n = 8) of the campaigns used single platforms, with the most common being Facebook, Instagram, blogs, and YouTube. Campaigns had mixed effects on cognitive outcomes (e.g., intention, attitude, knowledge), behavioral outcomes (e.g., food choices, PA), and anthropometric outcomes (e.g., weight, waist circumference).

Conclusion: Social media campaigns focused on promoting healthy eating, PA, and healthy weight had mixed effects on individual-level cognitive, behavioral, and anthropometric outcomes. Various limitations of the included studies make it difficult to ascertain which factors influence campaign effectiveness. Advancing knowledge in this area is important, particularly given social media's widespread use and potential for broad reach. New research with features such as rigorous study designs, larger and more diverse samples, and strong theoretical foundations may provide important insights into what types of interventions are effective or not and under what conditions.

目的:社交媒体是促进积极体重相关行为的有前途的健康传播渠道,但以前的研究还没有综合证据来证明社交媒体宣传活动对促进健康饮食、体育锻炼(PA)和健康体重的独立影响。本研究旨在填补这一空白,通过回顾测试此类活动对个人认知、行为和人体测量结果影响的研究结果,为未来基于社交媒体的肥胖预防研究和实践提供参考:在 Web of Science 和 PubMed 数据库中搜索了 2012 年至 2023 年间发表的同行评审文章,这些文章探讨了与健康饮食、PA 或体重管理相关的社交媒体活动的独立效果。对研究特点和结果进行了提取和总结:本综述共纳入 11 项研究,这些研究介绍了针对健康饮食相关结果(如水果和蔬菜消费、膳食准备、营养标签阅读)、PA 或体重管理的宣传活动。大多数活动(n = 7)都是由大学或研究中心开发的。重点受众包括家长、成年女性、青少年、大学生和成年政府雇员。大多数活动(n = 8)使用单一平台,其中最常见的是 Facebook、Instagram、博客和 YouTube。活动对认知结果(如意向、态度、知识)、行为结果(如食物选择、PA)和人体测量结果(如体重、腰围)的影响不一:结论:以促进健康饮食、PA 和健康体重为重点的社交媒体活动对个人层面的认知、行为和人体测量结果的影响不一。由于所纳入研究的各种局限性,很难确定哪些因素会影响活动的效果。尤其是考虑到社交媒体的广泛使用和潜在的广泛影响力,增进这方面的知识非常重要。具有严格的研究设计、更大和更多样化的样本以及坚实的理论基础等特点的新研究可能会为了解哪类干预措施有效或无效以及在什么条件下有效提供重要的见解。
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引用次数: 0
Continuous glucose monitoring captures glycemic variability in obesity after sleeve gastrectomy: A prospective cohort study. 连续血糖监测捕捉袖带胃切除术后肥胖症患者的血糖变化:前瞻性队列研究。
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-01-04 eCollection Date: 2024-02-01 DOI: 10.1002/osp4.729
Brenda Dorcely, Julie DeBermont, Akash Gujral, Migdalia Reid, Sally M Vanegas, Collin J Popp, Michael Verano, Melanie Jay, Ann Marie Schmidt, Michael Bergman, Ira J Goldberg, José O Alemán

Objective: HbA1c is an insensitive marker for assessing real-time dysglycemia in obesity. This study investigated whether 1-h plasma glucose level (1-h PG) ≥155 mg/dL (8.6 mmol/L) during an oral glucose tolerance test (OGTT) and continuous glucose monitoring (CGM) measurement of glucose variability (GV) better reflected dysglycemia than HbA1c after weight loss from metabolic and bariatric surgery.

Methods: This was a prospective cohort study of 10 participants with type 2 diabetes compared with 11 participants with non-diabetes undergoing sleeve gastrectomy (SG). At each research visit; before SG, and 6 weeks and 6 months post-SG, body weight, fasting lipid levels, and PG and insulin concentrations during an OGTT were analyzed. Mean amplitude of glycemic excursions (MAGE), a CGM-derived GV index, was analyzed.

Results: The 1-h PG correlated with insulin resistance markers, triglyceride/HDL ratio and triglyceride glucose index in both groups before surgery. At 6 months, SG caused 22% weight loss in both groups. Despite a reduction in HbA1c by 3.0 ± 1.3% in the diabetes group (p < 0.01), 1-h PG, and MAGE remained elevated, and the oral disposition index, which represents pancreatic β-cell function, remained reduced in the diabetes group when compared to the non-diabetes group.

Conclusions: Elevation of GV markers and reduced disposition index following SG-induced weight loss in the diabetes group underscores persistent β-cell dysfunction and the potential residual risk of diabetes complications.

目的:HbA1c 是评估肥胖症患者实时血糖异常的不敏感指标。本研究探讨了口服葡萄糖耐量试验(OGTT)期间 1 小时血浆葡萄糖水平(1-h PG)≥155 毫克/分升(8.6 毫摩尔/升)和连续葡萄糖监测(CGM)测量的葡萄糖变异性(GV)是否比 HbA1c 更能反映代谢和减肥手术减重后的血糖异常:这是一项前瞻性队列研究,研究对象为接受袖带胃切除术(SG)的 10 名 2 型糖尿病患者和 11 名非糖尿病患者。在接受袖带胃切除术前、术后 6 周和 6 个月的每次研究访问中,都对体重、空腹血脂水平、OGTT 期间的 PG 和胰岛素浓度进行了分析。还分析了血糖偏移的平均幅度(MAGE),这是一种由 CGM 导出的 GV 指数:结果:两组患者术前的 1 小时 PG 与胰岛素抵抗指标、甘油三酯/高密度脂蛋白比率和甘油三酯葡萄糖指数相关。6 个月后,SG 使两组患者的体重均减轻了 22%。尽管糖尿病组的 HbA1c 降低了 3.0 ± 1.3% (与非糖尿病组相比,糖尿病组的β细胞功能仍有所降低):结论:SG诱导糖尿病组体重减轻后,GV标志物升高,处置指数降低,这突显了持续的β细胞功能障碍和糖尿病并发症的潜在残余风险。
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引用次数: 0
Long term cost outcomes among commercially insured patients undergoing bariatric surgical procedures. 接受减肥手术的商业保险患者的长期成本结果。
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-01-01 eCollection Date: 2024-02-01 DOI: 10.1002/osp4.727
Sonali Shambhu, Qinli Ma, Aliza S Gordon, David Pryor, Joseph A Karam, Andrea DeVries

Objective: Bariatric procedures have become safer in recent years, warranting new data on long-term costs. This study examined the impact of bariatric procedures on a person's long-term healthcare costs up to 10 years and if it differed by socio-economic status (SES).

Methods: This retrospective observational study compared the downstream health care cost of patients with obesity who had undergone bariatric surgery (BS) between 2009 and 2018 to a 1:1 matched group of members with obesity but no surgery.

Results: 167,764 individuals from administrative claims data with an obesity diagnosis were included; 83,882 in the BS group and 83,882 in the non-surgical group. In follow-up years 2-10, the BS group was associated with lower total medical healthcare cost compared to the non-surgical group (cost ratios ranged 0.85-0.93, p values < 0.05). When stratifying the BS group by SES quartiles, there were no significant cost differences by SES (cost ratios ranged from 0.96 to 1.05, most p values > 0.05).

Conclusions: BS was associated with lower long-term follow-up medical cost and cost savings appeared similar among the SES quartiles in the BS group. The study results may help policy makers and employers in designing benefits and extending coverage for bariatric surgical procedures.

目的:近年来,减肥手术变得越来越安全,因此需要有关长期成本的新数据。本研究探讨了减肥手术对个人长达 10 年的长期医疗费用的影响,以及社会经济地位(SES)是否会对其产生影响:这项回顾性观察研究比较了2009年至2018年间接受减肥手术(BS)的肥胖症患者与未接受手术的肥胖症患者的下游医疗成本,两者的比例为1:1:从行政报销数据中纳入了167764名被诊断为肥胖症的患者,其中减肥手术组83882人,非手术组83882人。在随访的第 2-10 年,BS 组与非手术组相比,医疗保健总费用较低(费用比为 0.85-0.93 之间,P 值 > 0.05):结论:BS 与较低的长期随访医疗费用相关,而在 BS 组中,不同社会经济地位的四分位数所节省的费用似乎相似。研究结果可能有助于政策制定者和雇主设计减肥手术的福利并扩大其覆盖范围。
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引用次数: 0
Associations of daily weight management‐focused social support with weight loss, activity behaviors, and eating regulation in the context of metabolic and bariatric surgery 在代谢和减肥手术的背景下,以日常体重管理为重点的社会支持与体重减轻、活动行为和饮食调节的关系
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-10 DOI: 10.1002/osp4.717
Dale S. Bond, Kathryn E. Smith, Leah M. Schumacher, Sivamainthan Vithiananthan, Daniel B. Jones, Pavlos Papasavas, Jennifer Webster, J. Graham Thomas
Abstract Objective Greater perceived social support (PSS) is associated with more favorable changes in weight loss, activity behaviors, and eating regulation after metabolic and bariatric surgery (MBS). However, studies have relied on generic, retrospective PSS measures, and stability of PSS levels and relations with weight loss and weight‐related behaviors over time is unknown. Using smartphone‐based Ecological Momentary Assessment, this study evaluated pre‐to 1‐year post‐MBS changes in daily weight management‐focused PSS and associations with weight loss, device‐measured activity behaviors, and eating regulation before and during the initial year after MBS. Method Adult MBS patients ( n = 71) received (1) an accelerometer to measure daily moderate‐to‐vigorous intensity physical activity (MVPA) and sedentary time (ST) minutes/day, and (2) a smartphone to complete morning weight‐focused PSS ratings and eating regulation (dietary restraint/disinhibition) ratings at four semi‐random times daily for 10 days at pre‐ and 3, 6, and 12‐month postoperative. Generalized linear mixed models analyzed the associations of PSS with total weight loss (%TWL) and activity/eating outcomes. Results Participants on average reported relatively stable moderate‐to‐high PSS (3.98 on one to five scale) across assessments. Perceived social support was not related to %TWL, MVPA, or ST. Participants with higher PSS reported lower disinhibition and higher restraint than those with lower PSS (ps < 0.05); however, participants reported higher restraint on days that PSS was lower than their usual levels ( p = 0.009). Conclusions MBS patients on average had stable PSS levels across time. Higher PSS levels were associated with greater resistance to overeating cues (disinhibition) and cognitive control to restrict food intake (restraint) over time. Additionally, participants reported higher restraint when PSS levels were lower than usual. Overall, weight‐focused PSS appeared to hold greater importance in relation to regulating eating behavior than engaging in activity behaviors or weight loss among MBS patients during the initial postoperative year. Clinical Trial Registration NCT02777177.
【摘要】目的更大的感知社会支持(PSS)与代谢和减肥手术(MBS)后体重减轻、活动行为和饮食调节的更有利变化有关。然而,研究依赖于一般的、回顾性的PSS测量,PSS水平的稳定性及其与减肥和体重相关行为的关系尚不清楚。使用基于智能手机的生态瞬间评估,本研究评估了MBS前至1年后以日常体重管理为重点的PSS的变化,以及与体重减轻、设备测量的活动行为和MBS后最初一年的饮食调节之间的关系。方法成年MBS患者(n = 71)接受了(1)一个加速度计,用于测量每天中高强度体力活动(MVPA)和久坐时间(ST)分钟/天;(2)一个智能手机,用于完成以体重为中心的早晨PSS评分和饮食调节(饮食限制/去抑制)评分,每天4次,在术后前、3、6和12个月,持续10天。广义线性混合模型分析了PSS与总体重减轻(%TWL)和活动/饮食结果的关系。结果:在整个评估过程中,参与者平均报告了相对稳定的中高PSS(1 - 5量表为3.98)。感知社会支持与%TWL、MVPA或st无关。与较低PSS的参与者相比,PSS较高的参与者报告更低的去抑制和更高的约束(ps <0.05);然而,参与者在PSS低于正常水平的日子里报告了更高的克制(p = 0.009)。结论MBS患者平均PSS水平稳定。随着时间的推移,更高的PSS水平与更强的对暴饮暴食的抵抗力(去抑制)和限制食物摄入的认知控制(克制)有关。此外,当PSS水平低于平时时,参与者报告了更高的克制。总体而言,在术后最初一年中,体重为重点的PSS似乎在调节饮食行为方面比参与活动行为或减肥在MBS患者中具有更大的重要性。临床试验注册编号NCT02777177。
{"title":"Associations of daily weight management‐focused social support with weight loss, activity behaviors, and eating regulation in the context of metabolic and bariatric surgery","authors":"Dale S. Bond, Kathryn E. Smith, Leah M. Schumacher, Sivamainthan Vithiananthan, Daniel B. Jones, Pavlos Papasavas, Jennifer Webster, J. Graham Thomas","doi":"10.1002/osp4.717","DOIUrl":"https://doi.org/10.1002/osp4.717","url":null,"abstract":"Abstract Objective Greater perceived social support (PSS) is associated with more favorable changes in weight loss, activity behaviors, and eating regulation after metabolic and bariatric surgery (MBS). However, studies have relied on generic, retrospective PSS measures, and stability of PSS levels and relations with weight loss and weight‐related behaviors over time is unknown. Using smartphone‐based Ecological Momentary Assessment, this study evaluated pre‐to 1‐year post‐MBS changes in daily weight management‐focused PSS and associations with weight loss, device‐measured activity behaviors, and eating regulation before and during the initial year after MBS. Method Adult MBS patients ( n = 71) received (1) an accelerometer to measure daily moderate‐to‐vigorous intensity physical activity (MVPA) and sedentary time (ST) minutes/day, and (2) a smartphone to complete morning weight‐focused PSS ratings and eating regulation (dietary restraint/disinhibition) ratings at four semi‐random times daily for 10 days at pre‐ and 3, 6, and 12‐month postoperative. Generalized linear mixed models analyzed the associations of PSS with total weight loss (%TWL) and activity/eating outcomes. Results Participants on average reported relatively stable moderate‐to‐high PSS (3.98 on one to five scale) across assessments. Perceived social support was not related to %TWL, MVPA, or ST. Participants with higher PSS reported lower disinhibition and higher restraint than those with lower PSS (ps < 0.05); however, participants reported higher restraint on days that PSS was lower than their usual levels ( p = 0.009). Conclusions MBS patients on average had stable PSS levels across time. Higher PSS levels were associated with greater resistance to overeating cues (disinhibition) and cognitive control to restrict food intake (restraint) over time. Additionally, participants reported higher restraint when PSS levels were lower than usual. Overall, weight‐focused PSS appeared to hold greater importance in relation to regulating eating behavior than engaging in activity behaviors or weight loss among MBS patients during the initial postoperative year. Clinical Trial Registration NCT02777177.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"74 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135088363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparison of virtual and in person delivery of a full meal replacement program for obesity 一项针对肥胖的虚拟和面对面的全餐替代方案的比较
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-10-31 DOI: 10.1002/osp4.718
Matthew Skeldon, David Harris, Robert Dent, Judy Y Shiau
Abstract Objective Full meal replacement (FMR) Intensive Lifestyle Interventions (ILI) have been used for weight management. However, predictors of efficacy with these programs are less clear. The primary objective was to assess weight loss predictors in a community‐based FMR ILI program. A secondary objective was to determine if weight loss was different between virtual and in person ILI. Methods This was a retrospective cohort study involving 234 patients who started the program between 1 January 2016 and 3 March 2021. In the 24‐week program, patients spent 12 weeks on FMR and then transitioned back to food for the remainder, with weekly follow up with a physician and group sessions with a dietitian. Visits were in person prior to March 2020 and virtual afterward. Results Patients' average age was 47.5 years (SD = 12.0) and 73.5% were female. Average weight loss was 14.3% (SD = 6.2%). There was no significant difference in weight loss between virtual and in person programs. Patients on a Glucagon‐like Peptide‐1 Receptor Agonist prior lost less weight. Other significant associations between groups were baseline Hemoglobin A 1 C, classes attended, as well as the age since peak weight. Conclusion Weight loss from virtual ILI was not significantly different from person ILI. More research is needed to determine how to best stratify care as virtual or in person using FMR programs.
【摘要】目的采用全餐替代(FMR)强化生活方式干预(ILI)进行体重管理。然而,这些项目的疗效预测指标还不太清楚。主要目的是评估以社区为基础的FMR ILI项目中体重减轻的预测因素。第二个目的是确定虚拟ILI和真人ILI之间的体重减轻是否不同。方法:这是一项回顾性队列研究,涉及234名患者,他们在2016年1月1日至2021年3月3日期间开始该项目。在为期24周的项目中,患者花了12周的时间进行FMR治疗,然后在剩下的时间里恢复到食物治疗,每周有一位医生进行随访,并有一位营养师进行小组会议。2020年3月之前是亲自访问,之后是虚拟访问。结果患者平均年龄47.5岁(SD = 12.0),女性占73.5%。平均体重减轻14.3% (SD = 6.2%)。虚拟课程和真人课程在减肥方面没有显著差异。先前使用胰高血糖素样肽1受体激动剂的患者体重减轻较少。两组之间的其他显著关联是基线血红蛋白1c、参加的课程以及体重达到峰值后的年龄。结论虚拟ILI患者体重减轻与真人ILI患者无显著差异。需要更多的研究来确定如何最好地分层护理是虚拟还是亲自使用FMR程序。
{"title":"A comparison of virtual and in person delivery of a full meal replacement program for obesity","authors":"Matthew Skeldon, David Harris, Robert Dent, Judy Y Shiau","doi":"10.1002/osp4.718","DOIUrl":"https://doi.org/10.1002/osp4.718","url":null,"abstract":"Abstract Objective Full meal replacement (FMR) Intensive Lifestyle Interventions (ILI) have been used for weight management. However, predictors of efficacy with these programs are less clear. The primary objective was to assess weight loss predictors in a community‐based FMR ILI program. A secondary objective was to determine if weight loss was different between virtual and in person ILI. Methods This was a retrospective cohort study involving 234 patients who started the program between 1 January 2016 and 3 March 2021. In the 24‐week program, patients spent 12 weeks on FMR and then transitioned back to food for the remainder, with weekly follow up with a physician and group sessions with a dietitian. Visits were in person prior to March 2020 and virtual afterward. Results Patients' average age was 47.5 years (SD = 12.0) and 73.5% were female. Average weight loss was 14.3% (SD = 6.2%). There was no significant difference in weight loss between virtual and in person programs. Patients on a Glucagon‐like Peptide‐1 Receptor Agonist prior lost less weight. Other significant associations between groups were baseline Hemoglobin A 1 C, classes attended, as well as the age since peak weight. Conclusion Weight loss from virtual ILI was not significantly different from person ILI. More research is needed to determine how to best stratify care as virtual or in person using FMR programs.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"34 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135769513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient perspectives about treatment preferences for obesity with complications 患者对肥胖并发症治疗偏好的看法
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-10-29 DOI: 10.1002/osp4.720
Craig HC, Alsaeed D, Norris S, Holian J, Kennedy C, Feldman A, CW le Roux
Abstract Objective Obesity and many of its comorbidities can be improved by nutritional therapy, lifestyle modification, pharmacotherapy, and surgical intervention. Relatively little is known about patients' preferences for the range of obesity treatments. The present study was undertaken to identify factors that may influence these preferences. By evaluating patient‐preferred treatment options and factors influencing patients, treatment adherence and efficacy may be improved. Our objective was to identify factors that influence patient preferences and subsequent choice of obesity treatment among those seeking treatment for obesity‐related complications. Methods Participatory action research, using purposeful sampling, was used to recruit 33 patients with obesity complications. Recruitment took place in specialist clinics for non‐alcoholic fatty liver disease, diabetes, hypertension, and chronic kidney disease. Sixteen males and 17 females aged 18–70 years with a BMI>35 kg/m 2 were recruited. Prior to the interview, participants watched a 60‐min video explaining nutritional therapies, pharmacotherapies, and surgical therapies in equipoise. Data were collected in one‐to‐one semi‐structured interviews using zoom or the telephone; reflective thematic analysis was used. Results Four themes emerged: 1) structural factors, 2) autonomy, 3) interaction with formal care, and 4) the emotional and physical consequences of obesity. 39% of participants preferred nutritional therapy with support from medical professionals. 27% chose bariatric surgery. 24% chose pharmacotherapy alone, while 6% chose pharmacotherapy combined with nutritional therapy, 3% of participants wanted no intervention. Conclusion The challenges can be addressed by increasing support for healthcare professionals toward enhancing both their knowledge and the health literacy of patients. Future research should focus on improving access to treatment pathways for patients as well as developing health literacy programs and educational programs for healthcare professionals.
摘要目的通过营养治疗、生活方式改变、药物治疗和手术干预,可以改善肥胖及其许多合并症。相对而言,我们对患者对肥胖症治疗的偏好知之甚少。本研究旨在确定可能影响这些偏好的因素。通过评估患者首选的治疗方案和影响患者的因素,可以改善治疗依从性和疗效。我们的目的是确定影响患者偏好的因素,以及那些寻求肥胖相关并发症治疗的患者对肥胖治疗的后续选择。方法采用有目的抽样的参与式行动研究方法,对33例肥胖并发症患者进行调查。招募在非酒精性脂肪性肝病、糖尿病、高血压和慢性肾脏疾病的专科诊所进行。男性16名,女性17名,年龄18-70岁,体重35 kg/ m2。在访谈之前,参与者观看了一段60分钟的视频,讲解均衡的营养疗法、药物疗法和手术疗法。数据通过一对一的半结构化访谈收集,使用变焦或电话;采用反思性专题分析。结果出现了四个主题:1)结构性因素,2)自主性,3)与正规护理的相互作用,4)肥胖的情绪和身体后果。39%的参与者更喜欢在医疗专业人员的支持下进行营养治疗。27%的人选择了减肥手术。24%的人选择单独药物治疗,6%的人选择药物治疗联合营养治疗,3%的人不需要干预。结论增加对医护人员的支持,提高他们的知识和患者的健康素养,可以解决这些挑战。未来的研究应侧重于改善患者获得治疗途径的途径,以及为医疗保健专业人员制定健康素养计划和教育计划。
{"title":"Patient perspectives about treatment preferences for obesity with complications","authors":"Craig HC, Alsaeed D, Norris S, Holian J, Kennedy C, Feldman A, CW le Roux","doi":"10.1002/osp4.720","DOIUrl":"https://doi.org/10.1002/osp4.720","url":null,"abstract":"Abstract Objective Obesity and many of its comorbidities can be improved by nutritional therapy, lifestyle modification, pharmacotherapy, and surgical intervention. Relatively little is known about patients' preferences for the range of obesity treatments. The present study was undertaken to identify factors that may influence these preferences. By evaluating patient‐preferred treatment options and factors influencing patients, treatment adherence and efficacy may be improved. Our objective was to identify factors that influence patient preferences and subsequent choice of obesity treatment among those seeking treatment for obesity‐related complications. Methods Participatory action research, using purposeful sampling, was used to recruit 33 patients with obesity complications. Recruitment took place in specialist clinics for non‐alcoholic fatty liver disease, diabetes, hypertension, and chronic kidney disease. Sixteen males and 17 females aged 18–70 years with a BMI&gt;35 kg/m 2 were recruited. Prior to the interview, participants watched a 60‐min video explaining nutritional therapies, pharmacotherapies, and surgical therapies in equipoise. Data were collected in one‐to‐one semi‐structured interviews using zoom or the telephone; reflective thematic analysis was used. Results Four themes emerged: 1) structural factors, 2) autonomy, 3) interaction with formal care, and 4) the emotional and physical consequences of obesity. 39% of participants preferred nutritional therapy with support from medical professionals. 27% chose bariatric surgery. 24% chose pharmacotherapy alone, while 6% chose pharmacotherapy combined with nutritional therapy, 3% of participants wanted no intervention. Conclusion The challenges can be addressed by increasing support for healthcare professionals toward enhancing both their knowledge and the health literacy of patients. Future research should focus on improving access to treatment pathways for patients as well as developing health literacy programs and educational programs for healthcare professionals.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"63 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136134075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A qualitative study of perceived barriers and facilitators to interrupting sedentary behaviour among adults living with obesity 一项对肥胖成人中打断久坐行为的感知障碍和促进因素的定性研究
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-10-27 DOI: 10.1002/osp4.721
Fiona Curran, Carol Brennan, James Matthews, Grainne O’ Donoghue
Abstract Introduction Both obesity and sedentary behaviour (SB), are associated with negative health consequences including cardiovascular disease, diabetes, certain cancers and all‐cause mortality. To date, perceived barriers and facilitators to interrupting SB in adults living with obesity have not been identified. Objective This study aimed to identify these perceived barriers and facilitators by conducting a behavioural analysis underpinned by the theoretical domains framework (TDF) and the Capability, Opportunity, Motivation‐Behaviour (COM‐B) model, to enhance knowledge and inform future intervention development. Methods A purposive and snowball sample (N=21) of adults living with obesity took part in semi‐structured interviews, guided by the TDF, to investigate perceived barriers or facilitators to interrupting SB. Transcribed interviews were inductively coded using reflexive thematic analysis. Key themes and subthemes were generated by grouping similar and recurring codes. Finally, subthemes were mapped to the TDF and COM‐B. Results Five key themes were identified, which influence SB across all domains of living. These relate to (i) physical and mental wellbeing; (ii) motivational readiness; (iii) roles, responsibilities and support; (iv) weight bias and stigma and (v) the environment. These themes were then deductively mapped to all 14 TDF domains and all six of the COM‐B constructs. Conclusion A complex interplay of individual, societal and policy factors contribute to the development and habituation of SB patterns for adults living with obesity. Factors identified in this study could assist in the development of interventions, strategies and policies designed to interrupt or reduce sedentary behaviour for this population. This article is protected by copyright. All rights reserved.
肥胖和久坐行为(SB)都与心血管疾病、糖尿病、某些癌症和全因死亡率等负面健康后果有关。迄今为止,尚未发现肥胖成人中断SB的障碍和促进因素。本研究旨在通过基于理论领域框架(TDF)和能力、机会、动机-行为(COM - B)模型的行为分析来识别这些感知到的障碍和促进因素,以增强知识并为未来的干预发展提供信息。方法在TDF的指导下,有目的的雪球样本(N=21)参与了半结构化访谈,以调查中断SB的感知障碍或促进因素。使用反身性主题分析对转录的访谈进行归纳编码。主要主题和次级主题是通过将类似和重复出现的代码分组产生的。最后,将子主题映射到TDF和COM‐B。结果确定了影响SB生活各个领域的五个关键主题。这些涉及(i)身心健康;(ii)动机准备;(iii)角色、责任和支持;(四)体重偏见和污名化;(五)环境。然后将这些主题演绎映射到所有14个TDF域和所有6个COM - B结构。结论个体因素、社会因素和政策因素共同作用,促进了成人肥胖患者SB模式的发展和习惯化。本研究确定的因素可以帮助制定干预措施、策略和政策,旨在打断或减少这一人群的久坐行为。这篇文章受版权保护。版权所有。
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引用次数: 0
“Psychological well‐being as a motive for and result of post‐bariatric body contouring procedures” “心理健康作为减肥后身体塑形手术的动机和结果”
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-10-20 DOI: 10.1002/osp4.719
Authors Britta Pehlke, Filipa Oliveira, Charalampos Varnava, Fabian Nehls, Philipp Wiebringhaus, Maximilian Kueckelhaus, Tobias Hirsch, Alexander Frederik Dermietzel
Abstract Objective This study investigates whether psychological well‐being in post‐bariatric patients seeking body contouring procedures differ from those who do not seek body contouring procedures, those who have already undergone body contouring procedures, and those who are unsure about body contouring procedures. Methods An anonymous, nonrandomized, cross‐sectional survey study was designed. Psychological well‐being of four groups of post‐bariatric‐patients (undergone body contouring procedures, seeking body contouring procedures, not seeking body contouring procedures, unsure about body contouring procedures) was compared. Results A total of 345 patients were included in this study. No significant difference between patients seeking body contouring procedures and those not seeking body contouring procedures was found with regard to depressive symptoms, self‐esteem, and body image. Patients who had already undergone body contouring procedures scored lower on depressive symptoms (p=.035), and reported to feel more attractive (p<.001) and less insecure (p=.030) than patients who had not undergone body contouring procedures yet but seeked it. Satisfaction with the result of the body contouring procedures was associated with lower depression levels (p<.001), higher self‐esteem (p<.001) and a more positive body‐image (p<.001). Conclusions Depressive symptoms or a low self‐esteem are not motivational factors for post‐bariatric patients to seek body contouring procedures. body contouring procedures is, however, associated with improvement in psychological well‐being in post‐bariatric patients. The patients’ satisfaction with the result of the body contouring procedures is significantly associated with positive psychological well‐being. This article is protected by copyright. All rights reserved.
摘要目的本研究旨在探讨减肥后寻求身体塑形手术的患者的心理健康状况与未寻求身体塑形手术的患者、已经接受过身体塑形手术的患者以及不确定身体塑形手术的患者是否存在差异。方法采用匿名、非随机、横断面调查研究。我们比较了四组减肥后患者的心理健康状况(接受过身体塑形手术、寻求身体塑形手术、未寻求身体塑形手术、对身体塑形手术不确定)。结果本研究共纳入345例患者。在抑郁症状、自尊和身体形象方面,寻求身体轮廓手术的患者与未寻求身体轮廓手术的患者之间没有显著差异。已经接受过身体塑形手术的患者在抑郁症状上得分较低(p= 0.035),并且据报道,与尚未接受过身体塑形手术但寻求过的患者相比,他们感觉自己更有吸引力(p= 0.001),更少缺乏安全感(p= 0.030)。对身体轮廓手术结果的满意度与较低的抑郁水平(p<.001)、较高的自尊(p<.001)和更积极的身体形象(p<.001)相关。结论:抑郁症状或低自尊不是减肥后患者寻求身体塑形手术的动机因素。然而,身体轮廓手术与减肥后患者心理健康的改善有关。患者对塑形手术结果的满意度与积极的心理健康显著相关。这篇文章受版权保护。版权所有。
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引用次数: 0
Adipose triglyceride lipase gene expression in peripheral blood mononuclear cells of subjects with obesity and its association with insulin resistance, inflammation and lipid accumulation in liver 肥胖患者外周血单核细胞脂肪甘油三酯脂肪酶基因表达及其与胰岛素抵抗、炎症和肝脏脂质积累的关系
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-10-15 DOI: 10.1002/osp4.716
Samira Ezzati‐Mobaser, Sahar Yarahmadi, Nikta Dadkhah Nikroo, Mohammad Hasan Maleki, Zeynab Yousefi, Pegah Golpour, Mona Nourbakhsh, Mitra Nourbakhsh
Abstract Introduction Adipose triglyceride lipase (ATGL) is a crucial enzyme responsible for the release of fatty acids from various tissues. The expression of ATGL is regulated by insulin and this enzyme is linked to insulin resistance. On the other hand, ATGL‐mediated lipolysis is connected to macrophage function and thus ATGL is involved in inflammation and the pathogenesis of lipid‐related disorders. This study aims to investigate the correlation between ATGL, obesity, metabolic syndrome, and inflammation. Methods A total of 100 participants, including 50 individuals with obesity and 50 healthy particiapnts, were recruited for this study and underwent comprehensive clinical evaluations. Blood samples were collected to measure plasma lipid profiles, glycemic indices, and liver function tests. Additionally, peripheral blood mononuclear cells (PBMCs) were isolated and used for the assessment of the gene expression of ATGL, using real‐time PCR. Furthermore, PBMCs were cultured and exposed to lipopolysaccharides (LPS) with simultaneous ATGL inhibition, and the gene expression of inflammatory cytokines, along with the secretion of prostaglandin E2 (PGE2), were measured. Results The gene expression of ATGL was significantly elevated in PBMCs obtained from participants with obesity and was particularly higher in those diagnosed with metabolic syndrome. It exhibited a correlation with insulin levels and Homeostatic Model Assessment for Insulin Resistance (HOMA‐IR), and it was associated with lipid accumulation in the liver. Stimulation with LPS increased ATGL expression in PBMCs, while inhibition of ATGL attenuated the inflammatory responses induced by LPS. Conclusions Obesity and metabolic syndrome were associated with dysregulation of ATGL. ATGL might play a role in the upregulation of inflammatory cytokines and act as a significant contributor to the development of metabolic abnormalities related to obesity. This article is protected by copyright. All rights reserved.
脂肪甘油三酯脂肪酶(ATGL)是一种重要的酶,负责从各种组织中释放脂肪酸。ATGL的表达受胰岛素调控,该酶与胰岛素抵抗有关。另一方面,ATGL介导的脂肪分解与巨噬细胞功能有关,因此ATGL参与炎症和脂质相关疾病的发病机制。本研究旨在探讨ATGL与肥胖、代谢综合征和炎症的相关性。方法共招募100名受试者,包括50名肥胖个体和50名健康受试者,进行综合临床评估。采集血液样本测量血脂、血糖指数和肝功能测试。此外,分离外周血单个核细胞(PBMCs)并使用实时PCR技术评估ATGL基因表达。此外,培养PBMCs并将其暴露于同时抑制ATGL的脂多糖(LPS)中,测量炎症因子的基因表达以及前列腺素E2 (PGE2)的分泌。结果ATGL基因表达在肥胖参与者的pbmc中显著升高,在诊断为代谢综合征的参与者中尤其高。它与胰岛素水平和胰岛素抵抗稳态模型评估(HOMA‐IR)相关,并与肝脏脂质积累有关。LPS刺激增加了pbmc中ATGL的表达,而抑制ATGL则减轻了LPS诱导的炎症反应。结论肥胖和代谢综合征与ATGL异常相关。ATGL可能在炎症细胞因子的上调中发挥作用,并在与肥胖相关的代谢异常的发展中发挥重要作用。这篇文章受版权保护。版权所有。
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引用次数: 0
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Obesity Science & Practice
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