This study focuses on the granitic intrusions in the Chambishi-Nkana Basin of the Zambian Copperbelt, aiming to reveal their genesis, tectonic setting, emplacement age, and relationship with Cu-Co mineralization. LA-ICP-MS zircon U-Pb dating shows that the Chambishi granite formed at approximately 1951 Ma, and the Nchanga granite crystallized at approximately 890 Ma. Geochemical analyses indicate that these rocks are peraluminous S-type granites, characterized by high A/CNK values (>1.3), enrichment in light rare earth elements, and significant negative Eu anomalies (Eu/Eu*=21.38–38.28). Zircon Lu-Hf isotopic data suggest that the Chambishi granite originated from the mixing of mantle and crust-derived melts during the collision between the Bangweulu Block and the Tanzania Craton, while the Nchanga granite formed from crustal anatexis without significant mantle input in an intraplate rift environment associated with the breakup of Rodinia in the Neoproterozoic. Molybdenite Re-Os dating reveals that hydrothermal cross-cutting vein-type Cu-Mo mineralization occurred at approximately 496 Ma, coinciding with basin inversion during the late stage of the Lufilian collisional orogeny—this age only represents the timing of the late vein-type mineralization, not the entire mineralization history of the deposit. This study confirms that the late Lufilian orogeny provided tectonic channels for hydrothermal migration, and granitic intrusions provided favorable structural channels for hydrothermal migration, while tectonic-thermal effects of the late Lufilian orogeny supplied the necessary thermal driving force, jointly controlling the formation of hydrothermal cross-cutting vein-type Cu-Mo mineralization. The sedimentary layered Cu-Co mineralization is controlled by the Neoproterozoic sedimentary environment, and its specific formation age requires further dating of sulfides (e.g., carrollite) in the layered mineralization. By integrating geochronological and geochemical data, this research establishes a temporal framework for magmatic events, tectonic evolution, and mineralization in the Zambian Copperbelt, highlighting the critical control of regional tectonic-magmatic activities on Cu-Co mineralization.
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