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EFFECT OF DIFFERENT PLANTS EXTRACT ON ACETYLCHOLINESTERASE ACTIVITY OF AEDES AEGYPTI AND MUSCA DOMESTICA ADULTS 不同植物提取物对埃及伊蚊和家蝇成虫乙酰胆碱酯酶活性的影响
Pub Date : 2023-03-27 DOI: 10.57041/pjs.v74i1-1.805
Naila Riaz
The present study evaluated AChE inhibitory effect of three plants (Calotropis procera, Eucalyptus globulus and Mentha spicata) extract using Aedes aegypti and Musca domestica as model insects. The effect caused by plants was also compared with commonly used insecticides i.e., Chlorpyrifos. The WHO-recommended protocol was used for conducting bioassay tests against selected insects. Three different doses of plants extract were used. The mortality rate was assessed after 24 hours post-treatment. Using Ellman's assay, the AChE activity was determined by spectrophotometry at 412nm wavelength. There was a marked decline in the enzyme activity of treated groups compared to the control group. M. spicata treated groups proved to have high AChE inhibition power among three plants extract. While C. procera extract effectively control both Ae. aegypti and M. domestica. It is concluded that plants extract not only inhibits the AChE activity of insects but also controls them very proficiently.
本研究以埃及伊蚊和家蝇为模式昆虫,评价了三种植物(Calotropis procera, Eucalyptus globulus和Mentha spicata)提取物对乙酰胆碱酯酶的抑制作用。并与常用杀虫剂毒死蜱进行了比较。采用了世卫组织推荐的方案对选定的昆虫进行生物测定试验。使用了三种不同剂量的植物提取物。治疗后24小时评估死亡率。采用Ellman法,在412nm波长处分光光度法测定乙酰胆碱酯酶活性。与对照组相比,处理组的酶活性明显下降。结果表明,三种植物提取物中木皮草处理组对乙酰胆碱酯酶的抑制作用较强。果仁提取物对白纹伊蚊和白纹伊蚊均有较好的防治效果。埃及伊蚊和家蝇。由此可见,植物提取物不仅能抑制昆虫的乙酰胆碱酯酶活性,而且对昆虫的乙酰胆碱酯酶活性有很好的控制作用。
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引用次数: 1
ACCURACY OF PATIENTS AGE ASSESSMENT FROM FRONTAL CHEST RADIOGRAPHS 胸部正位片对患者年龄评估的准确性
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.819
M. Hameed, S.Mahar, B.Das, A.R.Khumaini, A.Ullah, M.Jamil
Background: Chest radiograph interpretation can be aided by knowing the patient'sage. Patients’ age is often assessed by radiologists from costal cartilage calcification assessment ofchest radiographs with anteroposterior views. Objectives: Therefore, we performed this research todetermine the precision of these radiologists in age estimation from CXRs. Methods: Ten radiologyexperts were selected to evaluate 3500 chest digital radiography with posterior-anterior images, inNational Institute of Child Health Karachi/JSMU from January 2022 to 2023. The most importantinclusion criteria were selecting normal or nearly normal radiographs in the study. Radiologists wereblind to patients actual age and were requested to determine patient’s age to closest decade from CXR.The respondents entered their responses in separate Excel spreadsheets. Results: A sum of 3,500CXRs was interpreted by radiologists, out of which 32.14% CXRs were correctly interpreteddetermining age at SD + 3 years, whereas 2375 CXRs were either overrated or underestimated(p<0.05) and misinterpreted the age of patients (2375/3500; 67.85%). Conclusion: Overall ageassessment from a frontal CXR was only 32.14% in our study; considerable disparities were identifiedin age estimation using CXRs. Yet, it would be fascinating to expand this academic endeavor throughartificial intelligence tools and possibly improving the precision of patient age prediction from CXR.This approach for determining the age will be useful for screening tests in the prospect.
背景:胸片的解释可以通过了解病人的情况来辅助。放射科医生通常通过胸片正位肋软骨钙化评估来评估患者的年龄。目的:因此,我们进行了这项研究,以确定这些放射科医生从cxr中估计年龄的准确性。方法:选择10名放射学专家对2022年1月至2023年1月在卡拉奇国立儿童健康研究所/JSMU进行的3500例胸部前后位数字x线片进行评估。最重要的入选标准是在研究中选择正常或接近正常的x线片。放射科医生对患者的实际年龄一无所知,并被要求确定患者的年龄,从CXR到最近十年。受访者在单独的Excel电子表格中输入他们的回答。结果:放射科医师共解读了3500份cxr,其中32.14%的cxr被正确解读,确定了SD + 3岁的年龄,而2375份cxr被高估或低估(p<0.05),并误解了患者的年龄(2375/3500;67.85%)。结论:在我们的研究中,正面CXR的总体年龄评估率仅为32.14%;在使用cxr进行年龄估计时发现了相当大的差异。然而,通过人工智能工具扩展这一学术努力,并可能提高CXR对患者年龄预测的准确性,将是一件令人着迷的事情。这种确定年龄的方法将对未来的筛查试验有用。
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引用次数: 0
VALUE ADDED FERTILIZERS AMELIORATE GRAIN YIELD AND NUTRITIONAL QUALITY OF MAIZE CROP 增值肥料改善了玉米作物的籽粒产量和营养品质
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.821
Z. Ali, M.Akram, M.A.Ali, M.Shoaib, M.Y.Khurshid, J.Iqbal, S.S.HShah, A.Khan, A.Mehboob
A field trial was conducted to gauge the impact of value added NPK fertilizer,Zarkhez Plus, (N:08%;P:23%; K;18%) and biologically activated Zinc coated Urea (BAZU) maize.Treatments consisted; Control (T1), Straight Fertilizers (DAP, MoP, Urea) (T2), Zarkhez Plus + BAZUas 1/3rd replacement of Urea (T3), Zarkhez Plus + BAZU as 2/3rd replacement of Urea (T4), andZarkhez Plus + BAZU as 1/3rd replacement of Urea (T5). Results suggested that plant height, stemgirth, rows cob-1, grains row-1, grains cob-1, thousand seed weight were significantly improved by theapplication of Zarkhez Plus and BAZU. Grain yield was increased upto 30% with the application ofZarkhez Plus and BAZU compared to straight fertilizers. Application of BAZU beyond 1/3rd of thetotal N requirement did not increase the grain yield significantly but improved grain quality withhigher Zn and K contents. Maize grain yield can be significantly increased with the application ofZerkhez Plus and replacing 1/3rd in-season N requirement with BAZU.
通过田间试验,测定了氮磷钾增值肥料Zarkhez Plus (N:08%;P:23%;K;18%)和生物活性锌包膜尿素(BAZU)玉米。治疗方法包括;对照(T1)、直肥(DAP、MoP、尿素)(T2)、Zarkhez Plus + bazu1 /3替代尿素(T3)、Zarkhez Plus + BAZU 2/3替代尿素(T4)、Zarkhez Plus + BAZU 1/3替代尿素(T5)。结果表明,施用扎克孜+和BAZU可显著提高水稻株高、茎长、行数1、粒数1、粒数1、千粒重。与直接施肥相比,施用zarkhez Plus和BAZU可使粮食产量提高30%。施用超过总氮需要量1/3的BAZU对产量的提高不显著,但对锌、钾含量较高的籽粒品质有改善作用。施用zerkhez Plus和以BAZU代替1/3的季氮需要量可显著提高玉米产量。
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引用次数: 0
DEMOGRAPHIC DETAILS COMPARISON OF ASTHMATIC PATIENTS IN THE DISTRICT OF SARGODHA 萨戈达地区哮喘患者的人口统计资料比较
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.823
U. Ullah, W.A.Khan, H.Mustafa, M.F.Sabar, S.F. H. Shah, S.G. Mohyuddin
Asthma is a chronic respiratory disease affecting a significant portion of thepopulation worldwide, including Pakistan. This study aimed to compare the demographic details ofasthmatic patients in the district of Sargodha, Pakistan. A cross-sectional study was conducted on 300asthmatic patients attending two tertiary care hospitals in the district of Sargodha. Data on age, gender,residence, occupation, education, and family history of asthma were collected through a structuredquestionnaire. The data were analyzed using SPSS version 23.0. The majority of the patients werefemales (54.7%), and the mean age was 38.5 years. Most of the patients were from rural areas (61.3%),and the majority were housewives (38%). A significant association was found between gender andoccupation (p<0.05). Moreover, a positive family history of asthma was reported by 28.7% of thepatients. The findings of this study suggest that asthma is more prevalent among females and peopleliving in rural areas in the district of Sargodha. The high percentage of positive family history indicatesa genetic predisposition to the disease. These results could be helpful for the development of effectiveasthma management strategies in the region.
哮喘是一种慢性呼吸道疾病,影响着包括巴基斯坦在内的世界上很大一部分人口。本研究旨在比较巴基斯坦萨戈达地区哮喘患者的人口统计细节。对在萨戈达区两所三级医院就诊的300名哮喘患者进行了横断面研究。通过结构化问卷收集年龄、性别、居住地、职业、教育程度和哮喘家族史等数据。数据分析采用SPSS 23.0版本。患者以女性居多(54.7%),平均年龄38.5岁。以农村患者居多(61.3%),以家庭主妇居多(38%)。性别与职业之间存在显著相关(p<0.05)。此外,28.7%的患者报告有哮喘家族史。这项研究的结果表明,哮喘在萨戈达区农村地区的女性和人群中更为普遍。高比例的阳性家族史表明有患此病的遗传倾向。这些结果可能有助于该地区制定有效的哮喘管理策略。
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引用次数: 0
STRATEGIC MANAGEMENT FRAMEWORK OF GROUND WATER QUALITY FOR HEALTH CARE ALONG JINNAH ROAD GUJRANWALA CITY 古吉兰瓦拉市真纳路沿线卫生保健地下水质量战略管理框架
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.832
M. Y. Raza, I.Ahmed, M.Ilyas
The objective of the research was to investigate/assess the water quality standardaccording to WHO because the study area of research was a canal distributary of 32 cusec dischargefor the period of 25 years up to 1972 and thereafter sewage remained flowing period for 50 years. In2021 PHE Department converted to 42” Ø sewer pipe and polluted water Nallah up to Noshehra Roadand constructed a metaled road. The seepage water samples were collected and tested by the NoshehraRoad Laboratory. Accordingly, the results identified the water-borne diseases, metals, chemical,biological, fecal, and E-coli bacteria. It was therefore necessary to research the causes of diseases forthe safety of health care. Drinking water remedial measures were asked of Health Deptt and otherconcerned Authorities related to Gujranwala City. The quality of water was assessed by comparingWHO standards. The seepage water contaminated was obtained through hand pumps and dug wellsbefore Municipal water distribution through overhead reservoirs (OHR) duly chlorinated by PublicHealth Engg Department now WASA and the Municipal Corporation. There are certain industries,falling untreated effluents in drains, causing cancer and other fatal diseases, through agricultural foods,due to sullage water irrigating the vegetables, in the vicinity of subrubs area of the city.
这项研究的目的是根据卫生组织调查/评估水质标准,因为研究的研究区域是一条运河的分流,在截至1972年的25年期间有32立方米的污水排放,此后的50年期间污水仍在流动。2021年,公共卫生部门将42英寸Ø污水管道和受污染的Nallah至Noshehra路,并建造了一条金属道路。渗水样本由noshehrroad实验室采集和测试。因此,结果确定了水传播疾病、金属、化学、生物、粪便和大肠杆菌。因此,为了保健的安全,有必要研究疾病的原因。向卫生部和与古杰兰瓦拉市有关的其他有关当局询问了饮用水补救措施。通过比较世卫组织标准对水质进行了评估。被污染的渗水是通过手泵和挖井获得的,然后由公共卫生工程系(现WASA)和市政公司通过架空水库(OHR)进行市政供水。在城市郊区附近,某些工业将未经处理的污水排入下水道,通过农业食品,由于污水灌溉蔬菜,导致癌症和其他致命疾病。
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引用次数: 0
WORKING PRINCIPLE AND INTELLIGENCE OF SMART INFUSION PUMP 智能输液泵的工作原理及智能化
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.829
S. W. Ali, M. Rehan, H. Zahid, M. Safwan, S. A. Syed, F. A. Siddiqui
There is a tremendous demand on the critical care resources due to the extensivespread of the ongoing coronavirus pandemic and the large number of patients requiring critical care.The efficacy of a device directly influences how long a patient lives since patients are often receivingcritical care. Smart infusion pump is a medical device that can drip fluids into the patient's body. Thisdevice is considered as one of the most safety-critical medical devices due to the way it functions andthe risks it presents. The main objective of this work is to develop an affordable infusion pump usingembedded technology. The main tactic is to develop equipment that can identify air bubbles in infusionpump tubing since even a little one might obstruct blood flow and result in mortality. This method mayprovide consumers an accurate result, making it the greatest method for identifying bubbles and savinglives.
由于冠状病毒大流行的广泛传播和大量需要重症监护的患者,对重症监护资源的需求巨大。设备的有效性直接影响患者的寿命,因为患者通常接受危重护理。智能输液泵是一种可以将液体滴入患者体内的医疗设备。由于其功能方式和存在的风险,该设备被认为是最安全的医疗设备之一。这项工作的主要目标是利用嵌入式技术开发一种经济实惠的输液泵。主要的策略是开发能够识别输液泵管中的气泡的设备,因为即使是很小的气泡也可能阻碍血液流动并导致死亡。这种方法可以为消费者提供准确的结果,使其成为识别气泡和挽救生命的最佳方法。
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引用次数: 0
APPRAISAL OF URBANIZATION AND ITS IMPACTS ON THE ALBEDO AND CLIMATE CHANGE OF THE PUNJAB-PAKISTAN: A SPATIO-TEMPORAL ANALYSIS 巴基斯坦旁遮普邦城市化及其对反照率和气候变化影响的时空分析
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.827
D. Amjad, S.A.Shirazi, F.Sarwar, R.W.Aslam, S.Kousar
The research is aimed at evaluating the process of urbanization and it’s spatio-temporal impacts on albedo and the changing climate of the Punjab. Climate change in urban areas has become a public focal point, as urban development in our present-day environment is one of the mostcritical aspects of human activities. The shift in the reflective properties of the surface is one of theparticular climatic consequences of urbanization which most researchers have overlooked (Albedo).Changes in urbanized land surface properties resulted in a global, regional, and local changes inbiochemical cycles and environment. This analysis aims to identify the urban land use of the 1990-2018 study area (decadal) and evaluate Albedo and Climatic Variables' trends over the selected region.This study will provide a complete code of classification in Google Earth Engine for researchers. InGoogle Earth Engine, the classification technique was utilized to detect urban areas and barren landcover types by applying coding over four images of 1990, 2000, 2010, and 2018 of Punjab Province.The Albedo maps were created in the same way for the years 2000 and 2018. Climatic maps werecreated from 1990 to 2018 by applying the Inverse Distance Weighted method in a GIS system. Therehas been an apparent increase in the urban area of Punjab Province from 1990 to 2018. The urban areahas increased from 1183.5342 km2 to 8396.4618 km2 during the study period. Results from climaticmaps showed hotspots in the areas that have undergone urbanization. Overall, the accuracy of theclassification images was 81-88 percent, which was foremost to achieve the objectives of the research.
本研究旨在评价城市化进程及其对旁遮普省反照率和气候变化的时空影响。城市地区的气候变化已经成为公众关注的焦点,因为当今环境下的城市发展是人类活动最关键的方面之一。地表反射特性的变化是城市化的特殊气候后果之一,但大多数研究人员都忽视了这一点(反照率)。城市化土地表面性质的变化导致了全球、区域和局部生物化学循环和环境的变化。该分析旨在确定1990-2018年研究区(年代际)的城市土地利用,并评估所选区域的反照率和气候变量的趋势。本研究将为研究人员提供完整的Google Earth Engine分类代码。在google Earth Engine中,通过对旁遮普省1990年、2000年、2010年和2018年的四幅图像进行编码,利用该分类技术检测城市地区和荒地覆盖类型。2000年和2018年的反照率地图也是以同样的方式绘制的。在GIS系统中应用逆距离加权方法创建了1990年至2018年的气候图。从1990年到2018年,旁遮普省城市地区的人口明显增加。研究期间,城市面积从1183.5342 km2增加到8396.4618 km2。气候图的结果显示,热点地区已经经历了城市化。总体而言,分类图像的准确率为81- 88%,这是实现研究目标的首要条件。
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引用次数: 0
A SURVEY ON MOBILE CLOUD COMPUTING PROBLEMS AND SOLUTIONS 移动云计算问题及解决方案综述
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.824
A Wajid, N. Nigar, S. Islam, M. K. Shahzad
Today, with the use of mobile devices everywhere and with the success of cloudcomputing, the concept of mobile cloud computing (MCC) has been introduced. MCC is anincorporation of cloud computing into the mobile environment. In MCC, computing resources such asmemory, processing and storage are not actually present at the device of user. Instead, these resourcesare moved on to a remote location known as cloud and are owned by some service provider. The useraccesses these resources through internet. The advantages associated with MCC are low initialinvestment by a user, low cost of operation and maintenance. There are also several problems relatedto the MCC which are limited battery life, storage and bandwidth, diverse operating systems of mobiledevices and security. Various solutions for MCC problems have been developed with their ownadvantages and disadvantages. This paper presents a survey of MCC, its architecture, its problems andexisting solution of those problems and advantages and disadvantages of different solutions.
今天,随着移动设备无处不在的使用和云计算的成功,移动云计算(MCC)的概念已经被引入。MCC是将云计算整合到移动环境中。在MCC中,内存、处理和存储等计算资源实际上并不存在于用户的设备上。相反,这些资源被转移到一个被称为云的远程位置,并由一些服务提供商拥有。用户通过internet访问这些资源。与MCC相关的优点是用户的初始投资低,操作和维护成本低。与MCC相关的问题还包括有限的电池寿命、存储和带宽、移动设备的不同操作系统和安全性。各种MCC问题的解决方案各有优缺点。本文介绍了中冶集团的概况、体系结构、存在的问题、存在的解决方案以及各种解决方案的优缺点。
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引用次数: 0
INSIGHT OF PANDEMIC COVID-19: DEVELOPMENTS AND CHALLENGES 洞察covid-19大流行:发展和挑战
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.831
M. A. Muneer, M. Arshad, G. Abbas, Maria Arshad, K. Munir, A. Iqbal, A. Mustafa, Q. Amin, M. A. Khan, R. A. M. Qureshi, Suhaila-al-Sheboul, F. Siddique, S. Tamim, I. A. Sheikh, Q. U. Ain, U. Mahboob, S. Jaffery, A. J. Tanveer, Abdulbasit
This review focuses on the characteristics of coronavirus disease-19 (COVID-19)including virus structure, ecoepidemiology and pathophysiology, signs and symptoms in infectedpeople, and data on virus pathogenicity, severity, and survivability in COVID-19 infected patients. Theemphasis is on immunological reactions, diagnosis, prophylactic methods, and the zoonoticsignificance of COVID-19. The authors feel that the review's contents will be valuable toepidemiologists, virologists, public health officials, diagnosticians, laboratory workers,environmentalists, and socioeconomic experts. It has information on the many types of coronavirusvariants, the disease situation in Pakistan and the WHO criteria for COVID-19 prevention is given.Moreover, lessons learned from the COVID-19 pandemic are also outlined.
本文综述了冠状病毒病-19 (COVID-19)的病毒结构、生态流行病学和病理生理学、感染者的体征和症状,以及COVID-19感染者的病毒致病性、严重程度和生存能力等方面的资料。重点是免疫反应、诊断、预防方法和COVID-19的人畜共患意义。作者认为,这篇综述的内容对流行病学家、病毒学家、公共卫生官员、诊断学家、实验室工作人员、环境学家和社会经济专家都很有价值。它提供了许多类型的冠状病毒变体、巴基斯坦的疾病情况以及世卫组织COVID-19预防标准的信息。此外,还概述了从2019冠状病毒病大流行中吸取的教训。
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引用次数: 0
A CASE STUDY OF DUST STORM EVENTS IN PAKISTAN USING NORMALIZED DUST DETECTION INDEX 用归一化沙尘探测指数分析巴基斯坦沙尘暴事件
Pub Date : 2023-03-01 DOI: 10.57041/pjs.v75i1.825
H. Yaqub, I.Younes, K. Mahmood, S. Mahmood
Currently dust storms are among the most prevalent global environmental issues.They are the early warning indicators for desertification and climate change. The study intends toanalyse dust event in Pakistan using normalized dust detection index (NDDI), brightness temperature(BT) and MODIS data of aerosol optical depth (AOD), deep blue angstrom exponent (AE), aerosolindex (AI) and HYSPLIT mass trajectory methods. It also highlighted the relationship between NDDI,BT and AOD. The threshold value of NDDI was 0.19 - 0.36 and BT ≤ 310.5 K. Data from CALIPSO,NCEP/NCAR reanalysis datasets were used to validate research’s findings. The results found NDDIand BT value for Pakistan and track the movement of dust storm from west to east especially at theheight of 5-10km. Dust storms are inversely proportional to relative humidity and pressure.
目前,沙尘暴是全球最普遍的环境问题之一。它们是荒漠化和气候变化的早期预警指标。利用归一化粉尘探测指数(NDDI)、亮度温度(BT)和气溶胶光学深度(AOD)、深蓝埃指数(AE)、气溶胶指数(AI)和HYSPLIT质量轨迹等MODIS数据对巴基斯坦的沙尘事件进行分析。它还强调了NDDI、BT和AOD之间的关系。NDDI阈值为0.19 ~ 0.36,BT≤310.5 K。使用来自CALIPSO、NCEP/NCAR再分析数据集的数据来验证研究结果。结果发现了巴基斯坦的nddi和BT值,并跟踪了沙尘暴从西向东的运动,特别是在5-10km高度。沙尘暴与相对湿度和相对压力成反比。
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引用次数: 0
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Pakistan journal of science
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