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INTERNET OF MEDICAL THINGS ENABLED CLOUD-BASED BREAST CANCER IDENTIFICATION WITH MACHINE LEARNING 医疗物联网通过机器学习实现了基于云的乳腺癌识别
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i3.784
K Parveen, S.Y.Siddiqui, M.Daud, G.Abbas
Breast cancer occurs when cells in the breast grow out of control. Breast cancer canspread outside the breast through lymph vessels and blood vessels when it spreads to other parts of thebody, it is said to have metastasized. Most breast cancer cases are reported in women who are 50 yearsand/or o40 years older. According to facts and figures shared by WHO (World Health Organization), itimpacts 2.1 million women every year and also causes the greatest number of cancer-related deathsamongst women. Whilst breast cancer rates are higher among women in more developed regions, ratesare increasing in nearly every region globally. Different machine learning algorithms have beenapplied to the dataset like Naïve Bayes (NB), J48 Decision tree, K-Nearest Neighbor (KNN) and ANN(Gradient Descent) have been applied among them ANN (Gradient Descent) produces the optimalresults among these classification algorithms. The proposed Internet of Medical Things EnabledCloud-Based Breast Cancer Identification with Machine Learning system model with 98.07 %accuracy has been achieved. For the proposed model 97.64 % sensitivity and 98.32 % specificity havebeen recorded. From the results produced by the proposed expert system, it's satisfactory to utilize itfor breast cancer diagnosis. The Proposed system model will be helpful for the diagnosis of breastcancer.
当乳腺细胞生长失控时,就会发生乳腺癌。当乳腺癌扩散到身体其他部位时,它可以通过淋巴管和血管扩散到乳房外,据说它已经转移了。大多数乳腺癌病例发生在50岁和/或40岁以上的妇女中。根据世卫组织(世界卫生组织)提供的事实和数据,癌症每年影响210万妇女,并在妇女中造成与癌症有关的死亡人数最多。虽然较发达地区妇女的乳腺癌发病率较高,但全球几乎每个地区的发病率都在上升。不同的机器学习算法已经应用于数据集,如Naïve贝叶斯(NB), J48决策树,k -近邻(KNN)和ANN(梯度下降)已被应用其中ANN(梯度下降)在这些分类算法中产生最优的结果。提出的基于医疗物联网的基于云的乳腺癌识别与机器学习系统模型已经实现了98.07%的准确率。该模型的灵敏度为97.64%,特异性为98.32%。从所提出的专家系统产生的结果来看,将其用于乳腺癌诊断是令人满意的。该系统模型将有助于乳腺癌的诊断。
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引用次数: 0
A CLINICAL NOTE ON CANINE TRYPANOSOMIASIS 犬锥虫病临床报告
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i2.774
A. A. Khan
Trypanosomes are widely distributed extra erythrocytic protozoan of animals. Wereported a Trypanosomes infection from the blood of a bulldog. An 18 months old male was presentedin the Pet Hospital of RCVetS, Lahore, Pakistan with a history of anorexia, emaciation, and pyrexia.Clinical examination of the dog indicated pale mucosa due and increase capillary refill time.Microscopic examination of blood films confirmed the Trypanosomes infection. Hematologicalanalysis of the blood of the dog indicated a decrease in Total erythrocyte count, hemoglobinconcentration, and Pack cell volume except for erythrocyte sedimentation rate. Differential leukocytecount revealed all parameters were unremarkable except Neutropenia, Eosinophilia, Lymphocytosis,and Thrombocytopenia. Serum analysis showed hyperproteinemia, elevated bilirubin, Blood ureanitrogen (BUN), Hypoglycaemia, and a decreased level of Gamma-glutamyl transferase (GGT). Thisdirected us to work on heamo parasites in companion animals.
锥虫是广泛分布于动物红细胞外的原生动物。报告了牛头犬血液中的锥虫感染。巴基斯坦拉合尔RCVetS宠物医院收治了一只18个月大的雄性,有厌食症、消瘦和发热史。临床检查显示犬粘膜苍白,毛细血管充盈时间增加。镜检血片证实为锥虫感染。血液学分析表明,除红细胞沉降率外,总红细胞计数、血红蛋白浓度和包细胞体积均下降。白细胞计数差异显示,除中性粒细胞减少症、嗜酸性粒细胞增多症、淋巴细胞增多症和血小板减少症外,其他参数均无显著差异。血清分析显示高蛋白血症,胆红素升高,血尿素氮(BUN),低血糖,γ -谷氨酰转移酶(GGT)水平降低。这引导我们研究伴侣动物体内的血液寄生虫。
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引用次数: 0
CONJUGATIVE EFFECT OF LOW COST ADSORBENT WITH LACCASE ENZYME FOR REDUCTION OF PULP AND PAPER EFFLUENT LOAD, ITS KINETICS AND THERMODYNAMICS 低成本吸附剂与漆酶对降低制浆造纸废水负荷的共轭效应及其动力学和热力学研究
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i3.786
J. Rabbani, S. Ahmad, M. Iqbal
Pulp and paper industrial effluent has the foremost role in environmental pollution. The key factor of the current study is to determine the conjugative effect of charcoal (60%) and alluvial soil (40%) mixture with laccase enzyme to lessen the effluent load of the pulp and paper industry. The adsorbent mixture of charcoal (60%) and alluvial soil (40%) was used for the adsorption of biological oxygen demand (BOD) chemical oxygen demand (COD), color, and lignin of effluent. The impact of pH, temperature, adsorbent concentration, and adsorption time on the removal procedure were studied. Adsorption equilibrium was achieved after 50 minutes with an agitation rate of 500 rpm at pH 6.0 at 25 degree. Results indicated that COD, BOD, color, and lignin were removed 86%, 80%, 60%, and 62% respectively. Moreover, the laccase enzyme also enhanced the reduction of these parameters as COD 95%, BOD 93% color 83%, and lignin 75%. The experimental batch equilibrium adsorption for COD and BOD was analyzed by Freundlich and Langmuir models and kinetics was also discussed by pseudo-first-order and pseudo-second-order. The BOD and COD data fitted to the pseudo-secondorder kinetic model. Thermodynamics parameters ∆G˚, ∆H˚, and ∆S˚ results indicated thatadsorption was nonspontaneous due to high TDS and lignin, endothermic in nature, and revealed an increase in randomnessand degree of disorderliness at adsorbent mixture during the present study. Consequently, the use of laccase enzyme incombination with an adsorbent mixture presents promising results and is applicable.  
制浆造纸工业废水是环境污染的主要来源。本研究的关键因素是确定木炭(60%)和冲积土(40%)混合物与漆酶的共轭作用,以减轻制浆造纸工业的排放负荷。采用木炭(60%)和冲积土(40%)混合吸附剂对出水的生物需氧量(BOD)、化学需氧量(COD)、颜色和木质素进行吸附。研究了pH、温度、吸附剂浓度和吸附时间对去除过程的影响。在25度、pH 6.0、搅拌速率为500转/分、搅拌50分钟后达到吸附平衡。结果表明,COD、BOD、颜色和木质素的去除率分别为86%、80%、60%和62%。此外,漆酶对COD还原率为95%,BOD还原率为93%,颜色还原率为83%,木质素还原率为75%。采用Freundlich和Langmuir模型分析了COD和BOD的实验间歇平衡吸附,并采用拟一阶和拟二阶模型讨论了动力学。BOD和COD数据符合拟二级动力学模型。热力学参数∆G˚、∆H˚和∆S˚的结果表明,由于高TDS和木质素,吸附是非自发的,本质上是吸热的,并且在本研究过程中,吸附剂混合物的随机性和无序程度有所增加。因此,漆酶与吸附剂混合使用具有良好的效果,是可行的。
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引用次数: 0
EFFECT OF DIFFERENT PLANS OF NUTRITION ON GROWTH, FEED EFFICIENCY, BLOOD METABOLITES AND RELATIVE ECONOMICS IN SAHIWAL HEIFERS 不同营养计划对萨希瓦尔小母牛生长、饲料效率、血液代谢产物及相关经济学的影响
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i2.776
F. Ahmad
This trial was designed with the objectives to select best and economical feedingstrategies to accelerate growth pattern for reducing age at maturity in buffalo heifers. Twenty Sahiwalheifers (Age = 24 ± 2-month and wt. = 200 ± 30 kg) were divided into four equal groups(n-5) on thebasis completely randomized design, Control group (D) of heifers was fed on green fodder only and noration was offered while test diets were comprised on TMR based on wheat straw (A), fodder(B) andsilage(C) with crude protein 10-11 percent. Feed intake of each experimental animal were recordeddaily. Animals were weighed at the start of experiment and fortnightly thereafter. Animals of group Cgained higher body weight (averaged 580 grams daily) comparing with other groups while animals ofgroup (D)fed on fodder only yielded very poorly growth. Dry Matter Intakes of all groups were similarand there was no effect of treatment of different plans of diet fed to animals. Dry matter, Crude proteinand crude fiber digestibility values were higher in animals fed total mixed ration based on corn silageand dry ration as compared to those fed other diets. Blood urea nitrogen values were higher in group Afed on TMR wheat straw based diet while blood glucose values were higher in animals of group B andC fed corn silage or green fodder based diet as indicator for availability of nutrients for growth.
本试验旨在选择最佳和经济的饲喂策略,以加速水牛小母牛的生长模式,降低其成熟期年龄。试验选用20头年龄为24±2月龄、体重为200±30 kg的萨希瓦勒小母牛,按照完全随机设计分为4组(n-5),对照组(D)只饲喂青饲料,饲喂无酚饲料,试验饲粮由粗蛋白质含量为10- 11%的麦秸(A)、饲料(B)和青贮(C)组成。每天记录每只实验动物的采食量。实验开始时称重,之后每两周称重一次。与其他组相比,试验组动物的体重(平均每天580克)较高,而饲喂饲料的(D)组动物的生长非常差。各组动物的干物质采食量基本相同,饲喂不同饲粮方案对动物的处理没有影响。玉米青贮与干日粮混合饲喂的干物质消化率、粗蛋白质消化率和粗纤维消化率均高于其他饲粮。TMR麦秸基础饲粮饲喂组血尿素氮值较高,B组和c组饲粮饲喂玉米青贮或青草料基础饲粮的血糖值较高,可作为生长营养物质利用率的指标。
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引用次数: 0
COMPARATIVE STUDY OF PREVALANCE OF GASTROINTESTINAL ENDOPARASITES IN INSTITUTIONAL HERDS OF NILI RAVI BUFFALO 机构水牛群胃肠道内寄生虫流行率的比较研究
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i2.772
I. Anwar
Gastrointestinal endoparasites have a great impact on livestock production. Currentresearch is conducted to realize the proper prevalence of gastrointestinal parasitical incursion in threeinstitutional buffalo herds in the Punjab Province. A total of 758 fecal samples were examined in farmand health laboratory, Buffalo Research Institute for a time duration of one year (July 2017 to June2018) from three institutional herds. The fecal samples collected from Livestock experiment stationBhunikey, Chak katora and Haroonabad were 227,208 and 323 respectively. Out of which 311 (41.02%) were found positive and different for parasites during the current duration of study. Thepervasiveness of different parasites including trematodes, nematodes, and diverse infestation inbuffaloes at Livestock Experiment Station Bhunikey was 25.50% (58/227), 14.90%(34/227), and4.80%(11/227) , while at Livestock Experiment Station Chak Katora it was 19.81%(64/323),17.64%(57/323) and 3.7%(12/323) percent respectively. Livestock Experiment Station Haroonabadshowed the prevalence of trematodes, nematodes and mixed infections as 24.51 %( 51/208), 6.70 %(14/208) and 4.80 %( 10/208). Maximum prevalence was observed from November to February(trematodes 24.01%, nematodes 13.81% and mixed infestation 3.4%) while minimum parasitism wasobserved from July to October (trematodes 20%, nematodes 3.5% and mixed infestation 1.2%). Thestudy that is conducted has varied results revealed that the occurrence of different gastrointestinalparasites in buffaloes is quite severe causing economical losses by reducing milk production. Bykeeping focus on this factor, a proper planned and strategic way of treatment and control program maybe designed to cover and control gastrointestinal parasitic contagions in buffaloes.
胃肠道内寄生虫对畜牧生产有很大影响。目前进行的研究是为了了解在旁遮普省的三个机构水牛群中胃肠道寄生虫入侵的适当流行程度。2017年7月至2018年6月,在布法罗研究所的农场和卫生实验室对来自三个机构牛群的758份粪便样本进行了为期一年的检查。在布尼基、恰克卡托拉和哈鲁纳巴德畜牧实验站采集的粪便样本分别为227,208份和323份。其中311例(41.02%)在本研究期间呈阳性或差异。布尼基畜牧实验站吸虫、线虫和多种侵染水牛的寄生虫分布率分别为25.50%(58/227)、14.90%(34/227)和4.80%(11/227),恰克卡托拉畜牧实验站分别为19.81%(64/323)、17.64%(57/323)和3.7%(12/323)。哈鲁纳巴畜牧试验站检出率分别为24.51%(51/208)、6.70%(14/208)和4.80%(10/208)。11 - 2月是寄生虫感染率最高的季节(吸虫24.01%,线虫13.81%,混合侵染3.4%),7 - 10月是寄生虫感染率最低的季节(吸虫20%,线虫3.5%,混合侵染1.2%)。所进行的研究有不同的结果表明,各种胃肠道寄生虫在水牛中的发生相当严重,造成了减少产奶量的经济损失。通过对这一因素的关注,可以设计出适当的计划和战略的治疗和控制方案,以覆盖和控制水牛胃肠道寄生虫感染。
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引用次数: 0
PHYLOGENETIC STUDY OF SLC11A1 GENE IN DOMESTIC ANIMALS 家畜slc11a1基因的系统发育研究
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i3.781
A. Manan, H.Mustafa, M.Tariq, W.A.Khan, J.Ahmad, U.Fatima, Number, M. Ikram, S. G. Mohyyuddin
Solute carrier family 11-member a1 gene (SLC11a1) previously is a functionalmember of metal ion-transport protein, earlier known as natural resistance-associated macrophageprotein 1 (NRAMP1). The cellular expression of this gene is restricted to phagocytic cells. Thefunction of this gene is to transport bivalent metal cations from the cytosol. The complex reaction ofFenon and Haber-Weiss of this gene reacts toxic antimicrobial radicals against microorganisms. Thisstudy investigates the evolutionary divergence of the SLC11a1 gene in domesticated farm animals.SLC11a1 gene sequences of domesticated farm animals were retrieved from NCBI GenBank. Theresults of this study revealed that there was substantial genetic variation in aligned sequences of theSLC11a1 gene within selected species. One ns-mutation (Q312K) was found in this study which isharmful. The phylogenetic trees showed some form of differentiation in the SLC11a1 gene sequence.The information on SLC11a1 polymorphism might be used to associate with disease resistance of farmanimals in Pakistan.
溶质载体家族11成员a1基因(SLC11a1)以前是金属离子运输蛋白的功能成员,早期被称为天然耐药相关巨噬蛋白1 (NRAMP1)。这种基因的细胞表达仅限于吞噬细胞。该基因的功能是从细胞质中运输二价金属阳离子。该基因的复合反应ofFenon和Haber-Weiss对微生物产生毒性抗微生物自由基。本研究探讨了SLC11a1基因在家养家畜中的进化差异。驯化家畜SLC11a1基因序列从NCBI GenBank中检索。本研究结果表明,在所选物种中,slc11a1基因的排列序列存在显著的遗传变异。本研究发现1个有害的n -突变(Q312K)。系统发育树显示SLC11a1基因序列存在一定的分化。SLC11a1多态性信息可能与巴基斯坦农畜抗病相关。
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引用次数: 0
FACTORS AFFECTING ON AGE AT FIRST CALVING IN CROSSBRED CATTLE MAINTAINED AT LES QADIRABAD DISTRICT SAHIWAL 影响les qadirabad地区杂交牛初产犊龄的因素
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i3.780
M. Ahmad, M.N.Tahir, F.Ahmad, S.S.Shah, M.Jahanzeb, M.Akhtar, R.H.Mirza, M.Ikram
The data on age at first calving for 539 records of crossbred cows of differentfilial/genetic groups were considered for the present investigation. These crossbreds belonged to eightfilial/genetic groups (F1, F2, F3, F4, F5, F6, F7 and F8) maintained at Livestock Experiment StationQadirabad District Sahiwal from 1991 to 2014 (24 years). The duration of 24 year was divided into 6periods (P1, P2, P3, P4, P5 and P6) of four years each. Each year was further divided into threeseasons as winter (November-February), summer (March- June) and spring (July-October) on the basisof geo-climatic conditions prevailing in the region. The overall population mean of age at first calvingwas determined 1261.88±9.934 days. The analysis of variance revealed significant effect of period ofcalving on age at first calving. The finding of this study shows that age at first calving was subjected tonon-genetic factor. Effect of season of calving on age at first calving was non- significant whichindicate breed characteristic to adaptation with environment. Meanwhile effect of filial/genetic groupwas significant on age at first calving. Therefore, from the result of this investigation it can bedetermined that improving the feeding, health and other husbandry practices are essential to enhancethe performance trait of this herd.
本研究利用539头不同子代/遗传群体杂交奶牛的初产犊龄数据。这些杂交种分属1991年至2014年(24年)在Sahiwal qadirabad区牲畜试验站饲养的8个子代/遗传群(F1、F2、F3、F4、F5、F6、F7和F8)。将24年分为6个时期(P1、P2、P3、P4、P5、P6),每个时期4年。根据该地区的地理气候条件,每年又分为冬季(11月至2月)、夏季(3月至6月)和春季(7月至10月)三个季节。种群初产犊平均年龄为1261.88±9.934天。方差分析表明,产犊期对初产犊龄有显著影响。本研究结果表明,初产犊年龄受非遗传因素的影响。产犊季节对初产犊龄的影响不显著,说明品种具有适应环境的特点。同时,子代/遗传组对初产犊龄的影响显著。因此,从本调查的结果可以确定,改善饲养、卫生和其他饲养方法对提高该畜群的生产性能至关重要。
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引用次数: 0
CHANGING LANDSCAPE PATTERNS AND ITS EFFECT ON RISING LAND SURFACE TEMPERATURE OF LAHORE-PAKISTAN 拉合尔-巴基斯坦景观格局变化及其对地表温度上升的影响
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i3.788
K. Shakrullah, S.A.Shirazi
The study intaimsto evaluate the impact of landscape (Land use land cover) changeson Land surface temperature (LST) by using GIS and Remote sensing (RS) techniques in Lahoreduring 2017–2021.Supervised Maximum Likelihood classification method was used to classify theland use and land cover classes. For retrieval of Land surface temperature, the Landsat 8 (Band 10)product level 2 was used. Barren land and built- up area were identified as the most leading LULCclasses respectively in the study area at the cost of vegetation cover and water bodies. The barren landclass increased from 55.9% to 63.81% ,while the Built-up class also increases from 13.5% to 18.46%during 2017-2021.Whereas , vegetation and water bodies both are exhibiting the decline. The declinein vegetation class was reported from 29.58% to 17.6% over the time 2017 to 2021.Overall, 0.3 %decrease is observed in water bodies. In 2017 the 3◦C decline is observed in land surface temperature(LST) value than 2021.Built-up and Vegetation classes can contribute a significant role in variation ofLST in comparison to the water bodies. These results will be very helpful to understand the LULCchanges and eventually it will assist the land management authorities, policy maker and town plannersas well.
本研究旨在利用GIS和遥感技术,评估拉合尔2017-2021年景观(土地利用、土地覆被)变化对地表温度的影响。采用监督最大似然分类法对土地利用和土地覆盖进行分类。地表温度的反演使用Landsat 8 (Band 10)产品2级。以植被覆盖和水体为代价,荒地和建成区分别是研究区最主要的土地利用类型。在2017-2021年期间,贫瘠土地类别从55.9%增加到63.81%,而建筑类别也从13.5%增加到18.46%。植被和水体均呈下降趋势。据报道,在2017年至2021年期间,植被类别从29.58%下降到17.6%。总体而言,水体中观察到的下降幅度为0.3%。2017年地表温度(LST)值比2021年下降3℃。与水体相比,建筑类和植被类在地表温度变化中起着重要作用。这些结果将有助于理解土地利用价值变化,并最终为土地管理部门、政策制定者和城市规划者提供帮助。
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引用次数: 0
PERFORMANCE EVALUATION OF DNA PATTERN MATCHING ALGORITHMS DNA模式匹配算法的性能评价
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i3.785
I. Aziz, S.Shoaib, K.S.Khurshid, T.Ahmad, M.Awais
Bioinformatics is a new area of research in which DNA, RNA and proteinssequences are dealt. To store, retrieve, analyze, match, align, search, and process these sequencesdifferent techniques are existed. Currently a lot of advancements in sequence analysis cause the drasticincrease in the DNA database sizes that require more efficient approaches encompass accuracy. Searchand analysis of DNA patterns can be performed by using various pattern matching algorithms in thecomputational biology. The aim of present study is to present taxonomy and performance evaluation ofthese pattern matching algorithms. The objective of this SLR is to set a research trend and to find amathematical model to estimate execution search time before scanning whole DNA sequence byfollowing a search strategy.
生物信息学是研究DNA、RNA和蛋白质序列的一个新领域。为了存储、检索、分析、匹配、对齐、搜索和处理这些序列,存在不同的技术。目前,序列分析的许多进步导致DNA数据库规模的急剧增加,这需要更有效的方法包括准确性。DNA模式的搜索和分析可以通过使用计算生物学中的各种模式匹配算法来执行。本研究的目的是提出这些模式匹配算法的分类和性能评价。本研究的目标是建立一个研究趋势,并找到一个数学模型来估计执行搜索时间,然后按照搜索策略扫描整个DNA序列。
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引用次数: 0
A REVIEW OF ANAEROBIC TREATMENT 厌氧处理技术综述
Pub Date : 2023-01-11 DOI: 10.57041/pjs.v74i2.778
T. A. Iqbal, Z.A. Dasti
Anaerobic digestion is the greatest substantial to treat waste and generates renewableenergy. For many decades this process plays a central role in research that alter waste into energy. Itdescribes the phase of anaerobic digestion and its operating parameters for the digesters. It also givesthe quantitative evaluation of the anaerobic digestion, which develops the method of effectiveness fortreating the substrate. Parameters play a crucial role in anaerobic digestion. On the other side, many thepeople who are concerned with its studies found the best criteria for applying the certain scales. In this,we discussed many factors that are linked with the anaerobic digester operations that ensured tomaximize its efficiency and its effectiveness. Various applications of anaerobic need to lessen the costand time of it. Factors that are linked with it speed up the process and help to enhance the yield of bioenergy production.
厌氧消化是处理废物和产生可再生能源的最有效方法。几十年来,这一过程在将废物转化为能源的研究中起着核心作用。介绍了厌氧消化的阶段及其消化器的操作参数。并对厌氧消化进行了定量评价,提出了处理底物的有效方法。参数在厌氧消化中起着至关重要的作用。另一方面,许多关注其研究的人找到了应用某些尺度的最佳标准。在此,我们讨论了与厌氧消化池操作相关的许多因素,以确保最大限度地提高其效率和有效性。厌氧的各种应用需要减少它的停留时间。与此相关的因素加速了这一过程,并有助于提高生物能源生产的产量。
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引用次数: 2
期刊
Pakistan journal of science
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