Pub Date : 2024-01-15DOI: 10.36106/paripex/6203624
Kiran Francis, Dennis Henry
Approximately a billion people are assessed to have skin,nail and hair fungal diseases; millions have mucosal candidiasis and higher than 150 million people have serious fungal diseases, which have a major effect on their lives or are deadly.Moreover,mortality associated with fungal disease at >1.6 million is like that of tuberculosis and >3-fold more than malaria. Socioeconomic, geo-ecological attributes and the rising number of at-risk people are the main factors for variation in occurrence and pervasiveness of fungal disease across the world. Fungal infections are influenced majorly by the HIV/AIDS pandemic, tuberculosis, chronic obstructive pulmonary disease, asthma and the rising occurrence of cancers in both developed and developing countries [ 1 – 4 ] worldwide. Fungal skin diseases were the most widespread skin disease globally in 2017 (10.09%) and in 2016, fungal skin diseases were ranked the fourth highest in the occurrence of disease (2.1 billion cases) when compared [5,6] to 328 different illnesses and injuries worldwide.
{"title":"COMPARISON OF FLUCONAZOLE AND GRISEOFULVIN IN TREATMENT TREATMENT OF TINEA","authors":"Kiran Francis, Dennis Henry","doi":"10.36106/paripex/6203624","DOIUrl":"https://doi.org/10.36106/paripex/6203624","url":null,"abstract":"Approximately a billion people are assessed to have skin,nail\u0000and hair fungal diseases; millions have mucosal candidiasis\u0000and higher than 150 million people have serious fungal\u0000diseases, which have a major effect on their lives or are\u0000deadly.Moreover,mortality associated with fungal disease at\u0000>1.6 million is like that of tuberculosis and >3-fold more than\u0000malaria. Socioeconomic, geo-ecological attributes and the\u0000rising number of at-risk people are the main factors for\u0000variation in occurrence and pervasiveness of fungal disease\u0000across the world. Fungal infections are influenced majorly by\u0000the HIV/AIDS pandemic, tuberculosis, chronic obstructive\u0000pulmonary disease, asthma and the rising occurrence of\u0000cancers in both developed and developing countries\u0000[ 1 – 4 ] worldwide. Fungal skin diseases were the most\u0000widespread skin disease globally in 2017 (10.09%) and in\u00002016, fungal skin diseases were ranked the fourth highest in\u0000the occurrence of disease (2.1 billion cases) when compared\u0000[5,6] to 328 different illnesses and injuries worldwide.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/1603792
Mehmet Dalkiz, Aysenur Ozer, Ibrahim Serhat Dalkiz
In recent years, with the advancement of technology, dental diagnostic and treatment applications have become more efficient and cost-effective.Digital diagnostic and treatment methods that shorten the processes have started to be used. New methods and technical equipment continue to be developed. Digital imaging systems, robotic surgery applications,intra- and extraoral scanning systems,CAD-CAM systems,3D printing,3D modeling and analysis methods, digital orthodontics,digital cephalometry,invisalign endodontic biomicroscopes,apex locators and endodontic rotary systems have been used in recent years.The improvement of digital restorative production systems has allowed dentists to choose restorative materials different from traditional ones,to produce restorations within the clinic and also to reduce laboratory workflows.The first step of dental digital systems was digital cameras.With the development of intraoral and laboratory scanner cameras, digital imaging systems moved to another phase. This was followed by computer-aided diagnosis,treatment planning,digital design and production,and the construction of restorations.With the discovery of artificial intelligence, a new chapter in digital dentistry was opened. Success in digital dentistry depends on the precision and accuracy of digital devices and the knowledge and skills of dental personnel using digital devices and methods.This study aims to present current approaches to digital dentistry.
{"title":"SYSTEMATIC LITERATURE REVIEW OF THE DIGITAL DENTISTRY","authors":"Mehmet Dalkiz, Aysenur Ozer, Ibrahim Serhat Dalkiz","doi":"10.36106/paripex/1603792","DOIUrl":"https://doi.org/10.36106/paripex/1603792","url":null,"abstract":"In recent years, with the advancement of technology, dental diagnostic and treatment applications have become more\u0000efficient and cost-effective.Digital diagnostic and treatment methods that shorten the processes have started to be used.\u0000New methods and technical equipment continue to be developed. Digital imaging systems, robotic surgery\u0000applications,intra- and extraoral scanning systems,CAD-CAM systems,3D printing,3D modeling and analysis methods,\u0000digital orthodontics,digital cephalometry,invisalign endodontic biomicroscopes,apex locators and endodontic rotary\u0000systems have been used in recent years.The improvement of digital restorative production systems has allowed dentists\u0000to choose restorative materials different from traditional ones,to produce restorations within the clinic and also to reduce\u0000laboratory workflows.The first step of dental digital systems was digital cameras.With the development of intraoral and\u0000laboratory scanner cameras, digital imaging systems moved to another phase. This was followed by computer-aided\u0000diagnosis,treatment planning,digital design and production,and the construction of restorations.With the discovery of\u0000artificial intelligence, a new chapter in digital dentistry was opened. Success in digital dentistry depends on the\u0000precision and accuracy of digital devices and the knowledge and skills of dental personnel using digital devices and\u0000methods.This study aims to present current approaches to digital dentistry.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"10 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/4902712
Shrinivasa K R, Avinash Kate
Cultural heritage is an expression of the way of living developed by a community and passed down from generation to generation. It includes tangible cultures such as buildings, monuments, landscapes, books and art; and intangible cultures such as folklore, traditions, language and knowledge. For centuries scholars from all over the world have paid tributes to the rich culture of India. One such culturally rich state in India is Gujarat. Gujarat's traditional textiles and crafts play a predominant role in the apparel and visual identity of the state and its people. The form itself is the amalgamation and continuity of human potential, which is demonstrated by the glorious Karigiri, The craftsmanship of the natives of Gujarat. The state's karigars (artisans) have produced an exquisite projects for daily and ceremonial uses for centuries. The artisans source their materials locally and create products that perfectly blend indigenous skills and techniques with the right imagination. Natural resources like clay, wood, stone, metal, cotton yarn, animal hide and various flowers have been adopted and fashioned into multiple designs. What exists, as a result, is a fascinating balance between nature and humans, form and function. The research will facilitate the importance of line and colour in the traditional textiles of Gujarat. Design Aesthetics is a conceptual phenomenon that manifests different elements and components of which cords and colours are of primary importance. The symphony of lines and colour creates a world of aesthetically composed designs that become a significant component of applied art.
{"title":"CULTURAL TRANSFORMATION BY DESIGN: SYMPHONY OF LINE AND COLOUR IN THE TRADITIONAL TEXTILE DESIGNS OF GUJARAT","authors":"Shrinivasa K R, Avinash Kate","doi":"10.36106/paripex/4902712","DOIUrl":"https://doi.org/10.36106/paripex/4902712","url":null,"abstract":"Cultural heritage is an expression of the way of living developed by a community and passed down from generation to\u0000generation. It includes tangible cultures such as buildings, monuments, landscapes, books and art; and intangible\u0000cultures such as folklore, traditions, language and knowledge. For centuries scholars from all over the world have paid\u0000tributes to the rich culture of India. One such culturally rich state in India is Gujarat. Gujarat's traditional textiles and crafts\u0000play a predominant role in the apparel and visual identity of the state and its people. The form itself is the amalgamation\u0000and continuity of human potential, which is demonstrated by the glorious Karigiri, The craftsmanship of the natives of\u0000Gujarat. The state's karigars (artisans) have produced an exquisite projects for daily and ceremonial uses for centuries.\u0000The artisans source their materials locally and create products that perfectly blend indigenous skills and techniques\u0000with the right imagination. Natural resources like clay, wood, stone, metal, cotton yarn, animal hide and various flowers\u0000have been adopted and fashioned into multiple designs. What exists, as a result, is a fascinating balance between nature\u0000and humans, form and function. The research will facilitate the importance of line and colour in the traditional textiles of\u0000Gujarat. Design Aesthetics is a conceptual phenomenon that manifests different elements and components of which\u0000cords and colours are of primary importance. The symphony of lines and colour creates a world of aesthetically\u0000composed designs that become a significant component of applied art.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"35 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/9403483
Sumit Kumar Jain, Sherin Samuel
Coccydynia is a painful condition of the tail-bone region. It affects the activities of daily living mainly involving long periods of sitting. Several different treatment options have been reported in the literature but with variable outcomes. The objective of this prospective case series was to assess the outcomes of conservative treatment for patients with coccydynia. Patients clinically and radio-graphically diagnosed with coccydynia underwent a set of rehabilitation protocols. They were assessed pre-treatment and 3 months post-treatment on the basis of visual analogue scale and Oswestry low back disability questionnaire.The results of the case series suggest that the conservative treatment offer excellent outcome.
{"title":"COCCYDYNIA- THE EFFICACY OF REHABILITATION PROTOCOLS- A CASE SERIES.","authors":"Sumit Kumar Jain, Sherin Samuel","doi":"10.36106/paripex/9403483","DOIUrl":"https://doi.org/10.36106/paripex/9403483","url":null,"abstract":"Coccydynia is a painful condition of the tail-bone region. It affects the activities of daily living mainly involving long\u0000periods of sitting. Several different treatment options have been reported in the literature but with variable outcomes.\u0000The objective of this prospective case series was to assess the outcomes of conservative treatment for patients with\u0000coccydynia. Patients clinically and radio-graphically diagnosed with coccydynia underwent a set of rehabilitation\u0000protocols. They were assessed pre-treatment and 3 months post-treatment on the basis of visual analogue scale and\u0000Oswestry low back disability questionnaire.The results of the case series suggest that the conservative treatment offer\u0000excellent outcome.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/9400142
Virender Kumar, Rajesh Rohilla, Shagnik Paul, Paul Therattil, Saurabh Yadav, Devbrath Manna
Lipofibromatous Hamartoma (LFH) is rare condition involving diffuse peripheral nerve infiltration by normal appearing fibrous and adipose tissues. The cause and pathophysiology of LFH remains unclear however commonly proposed etiologies are congenital malformation and trauma. LFH affect the median nerve mainly but also buccinators, sciatic, superficial peroneal, posterior interosseous nerve, radial nerve, ulnar nerve, even the entire brachial plexus. Patients present with gradually enlarging non-tender lesions in the affected nerve distribution. Patient complains of numbness and tingling sensation. Motor deficits are a late finding. The majority of cases are diagnosed within the first three decades, with a mean age of 22.3 in remote cases and 22.0 in subjects presenting with macrodactyly. There are numerous overlapping clinical features with other conditions like klippal-Trenaunay-Weber syndrome, Hypertropic mononeuritis and congenital lymphedema. Upper extremity morphology includes mass, hypertrophy, macrodactyly, syndactyl, radial or ulnar deviation of phalanx , neurological symptoms including dysesthesia, paresthesia, motor deficits, cafe-au- lait spots, port wine stains, neurofibromatosis. On physical examination, the mass is soft, firm, nonfluctuant, mobile, minimally tender. Neurological deficits associated with LFH are hypesthesia, decreased grip, pinch, opposition strength and paraesthesia, yielding positive Tinel's and phalen's test. Tumors mimicking LFH of the median nerve include ganglion cyst, Déjerine Sottas disease, Klippel-Trénaunay-Weber syndrome, lipoma, and traumatic neuroma, neurofibroma and schwannoma. MRI, CT, Nerve Conduction Study, Electromyogram gets us closer to the diagnosis. Biopsy and histopathological examination are the only definitive means of LFH diagnosis. Care must be taken to rule out potentially malignant tumors. Treatment goals for LFH are symptom prevention, symptomatic relief, function, and aesthetics. Conservative approach can be offered to patients who present with an asymptomatic swelling without severe neurological impairment. There are two options of surgery. One is staged debulking and other Epiphysiodesis in a growing child. For cosmetic reasons, surgical debulking can only be undertaken if the risk of nerve damage is minimal. Digital amputation is usually reserved for severe cases refractory to debulking procedures.
{"title":"LIPOFIBROMATOUS HAMARTOMA OF PERIPHERAL NERVE- A RARE AND CHALLENGING ENTITY","authors":"Virender Kumar, Rajesh Rohilla, Shagnik Paul, Paul Therattil, Saurabh Yadav, Devbrath Manna","doi":"10.36106/paripex/9400142","DOIUrl":"https://doi.org/10.36106/paripex/9400142","url":null,"abstract":"Lipofibromatous Hamartoma (LFH) is rare condition involving diffuse peripheral nerve infiltration by normal appearing\u0000fibrous and adipose tissues. The cause and pathophysiology of LFH remains unclear however commonly proposed\u0000etiologies are congenital malformation and trauma. LFH affect the median nerve mainly but also buccinators, sciatic,\u0000superficial peroneal, posterior interosseous nerve, radial nerve, ulnar nerve, even the entire brachial plexus. Patients\u0000present with gradually enlarging non-tender lesions in the affected nerve distribution. Patient complains of numbness\u0000and tingling sensation. Motor deficits are a late finding. The majority of cases are diagnosed within the first three\u0000decades, with a mean age of 22.3 in remote cases and 22.0 in subjects presenting with macrodactyly. There are numerous\u0000overlapping clinical features with other conditions like klippal-Trenaunay-Weber syndrome, Hypertropic mononeuritis\u0000and congenital lymphedema. Upper extremity morphology includes mass, hypertrophy, macrodactyly, syndactyl, radial\u0000or ulnar deviation of phalanx , neurological symptoms including dysesthesia, paresthesia, motor deficits, cafe-au- lait\u0000spots, port wine stains, neurofibromatosis. On physical examination, the mass is soft, firm, nonfluctuant, mobile,\u0000minimally tender. Neurological deficits associated with LFH are hypesthesia, decreased grip, pinch, opposition strength\u0000and paraesthesia, yielding positive Tinel's and phalen's test. Tumors mimicking LFH of the median nerve include\u0000ganglion cyst, Déjerine Sottas disease, Klippel-Trénaunay-Weber syndrome, lipoma, and traumatic neuroma,\u0000neurofibroma and schwannoma. MRI, CT, Nerve Conduction Study, Electromyogram gets us closer to the diagnosis.\u0000Biopsy and histopathological examination are the only definitive means of LFH diagnosis. Care must be taken to rule out\u0000potentially malignant tumors. Treatment goals for LFH are symptom prevention, symptomatic relief, function, and\u0000aesthetics. Conservative approach can be offered to patients who present with an asymptomatic swelling without severe\u0000neurological impairment. There are two options of surgery. One is staged debulking and other Epiphysiodesis in a\u0000growing child. For cosmetic reasons, surgical debulking can only be undertaken if the risk of nerve damage is minimal.\u0000Digital amputation is usually reserved for severe cases refractory to debulking procedures.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"53 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cervical lesions are most commonly seen in sexually active women. These lesions may be non-neoplastic and neoplastic. Categorization and familiarity of the cervical non-neoplastic lesions with their histopathological findings are essential in their recognition and could improve the approach toward better management of the patient. This study was conducted with the aim to access the histomorphological pattern of diseases encountered in cervical biopsies and to study the association between clinical presentation and histopathological patterns of different cervical lesions. This study clinicopathological spectrum of cervical lesions was carried out in the Department of Pathology, SMS Medical College, Jaipur over 1.5 years from April 2020 to October 2021 In our study a total of 100 cervical biopsies were taken for study. The most common age group was 41 to 50 years. White discharge per vagina was the most common presenting feature in benign cervical lesions. Abnormal bleeding per vagina was in malignant cervical lesions. Benign cervical lesions were more common as compared to premalignant & malignant cervical lesions with chronic non-specific cervicitis being the most common of all lesions. Among malignancies, squamous cell carcinoma was the most common entity. It can be concluded that the key to correct interpretation and diagnosis depends upon careful correlation between cervical histology & clinical data which eventually helps in reducing morbidity by early detection of malignant and premalignant lesions and their timely management
{"title":"CLINICOPATHOLOGICAL SPECTRUM OF LESIONS IN CERVICAL BIOPSIES AT SMS MEDICAL COLLEGE AND ATTACHED HOSPITALS","authors":"Saroj Pachori, Laghuta Verma, Parmendra Pachori, Moullik Pachori","doi":"10.36106/paripex/9404059","DOIUrl":"https://doi.org/10.36106/paripex/9404059","url":null,"abstract":"Cervical lesions are most commonly seen in sexually active women. These lesions may be non-neoplastic and\u0000neoplastic. Categorization and familiarity of the cervical non-neoplastic lesions with their histopathological findings are\u0000essential in their recognition and could improve the approach toward better management of the patient. This study was\u0000conducted with the aim to access the histomorphological pattern of diseases encountered in cervical biopsies and to\u0000study the association between clinical presentation and histopathological patterns of different cervical lesions. This\u0000study clinicopathological spectrum of cervical lesions was carried out in the Department of Pathology, SMS Medical\u0000College, Jaipur over 1.5 years from April 2020 to October 2021 In our study a total of 100 cervical biopsies were taken for\u0000study. The most common age group was 41 to 50 years. White discharge per vagina was the most common presenting\u0000feature in benign cervical lesions. Abnormal bleeding per vagina was in malignant cervical lesions. Benign cervical\u0000lesions were more common as compared to premalignant & malignant cervical lesions with chronic non-specific\u0000cervicitis being the most common of all lesions. Among malignancies, squamous cell carcinoma was the most common\u0000entity. It can be concluded that the key to correct interpretation and diagnosis depends upon careful correlation\u0000between cervical histology & clinical data which eventually helps in reducing morbidity by early detection of malignant\u0000and premalignant lesions and their timely management","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"54 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140506945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/3405863
Anushree Cs, Rashmi Bv, R. Aggarwal
Introduction: Hyperbilirubinemia is a major health condition seen in approximately 60% of term and 80% preterm neonates. Total serum bilirubin (TSB) estimation is the gold standard method and is the most common reason of blood drawing in neonates. Non-invasive method like transcutaneous bilirubin (TCB) estimation is an alternative for bilirubin estimation. Thus, the primary aim of present study is to compare the efficacy of the two methods. Th Methods: is prospective observational study was conducted between 2020-2022 on 836 neonates (>35 weeks, ≥2000gm) at Mazumdar Shaw Medical Centre, Narayana health city, Bangalore aimed to compare TSB and transcutaneous bilirubin (TCB) values using JM-105 bilirubinometer assessed TCB values taken before, during and phototherapy from covered and uncovered skin of different sites and correlated with the serum bilirubin values, through linear regression and Bland Altman analysis. Positive correlations were observed between TSB and TCB values at the forehead, st Results: ernum, and pubic symphysis, with the strongest correlation at the forehead (r-0.826, p<0.001) pre-phototherapy. Correlation weakened during and after phototherapy, notably at the forehead post-phototherapy (r-0.121, p>0.05). The preferred TCB estimation site was forehead pre- and 12 hours post-phototherapy with mean difference of 2.15±2.1 mg/dl and 0.6±2.13 mg/dl respectively, while sternum was favored site at 24 hours post-phototherapy; with mean difference of 2.01±2.32 mg/dl.TCB cut-off values (13.75mg/dl) demonstrated sensitivity (78.5%) and specificity (64.5%) for discontinuing phototherapy (ROC AUC 0.774, p<0.05). TCB proves effective as a non-invasive screenin Conclusion: g tool for bilirubin estimation, alleviating the need for repeated blood draws. However, caution is advised regarding TCB's reliability during phototherapy monitoring. The study provides valuable insights into TCB's clinical applicability, offering practical recommendations for optimal usage.
{"title":"A PROSPECTIVE COHORT STUDY TO DETERMINE CORRELATION BETWEEN TRANSCUTANEOUS BILIRUBIN AND SERUM BILIRUBIN VALUES IN NEONATES WITH HYPERBILIRUBINEMIA IN A TERTIARY CARE HOSPITAL","authors":"Anushree Cs, Rashmi Bv, R. Aggarwal","doi":"10.36106/paripex/3405863","DOIUrl":"https://doi.org/10.36106/paripex/3405863","url":null,"abstract":"Introduction: Hyperbilirubinemia is a major health condition seen in approximately 60% of term and 80% preterm\u0000neonates. Total serum bilirubin (TSB) estimation is the gold standard method and is the most common reason of blood\u0000drawing in neonates. Non-invasive method like transcutaneous bilirubin (TCB) estimation is an alternative for bilirubin\u0000estimation. Thus, the primary aim of present study is to compare the efficacy of the two methods. Th Methods: is\u0000prospective observational study was conducted between 2020-2022 on 836 neonates (>35 weeks, ≥2000gm) at\u0000Mazumdar Shaw Medical Centre, Narayana health city, Bangalore aimed to compare TSB and transcutaneous bilirubin\u0000(TCB) values using JM-105 bilirubinometer assessed TCB values taken before, during and phototherapy from covered\u0000and uncovered skin of different sites and correlated with the serum bilirubin values, through linear regression and Bland\u0000Altman analysis. Positive correlations were observed between TSB and TCB values at the forehead, st Results: ernum,\u0000and pubic symphysis, with the strongest correlation at the forehead (r-0.826, p<0.001) pre-phototherapy. Correlation\u0000weakened during and after phototherapy, notably at the forehead post-phototherapy (r-0.121, p>0.05). The preferred\u0000TCB estimation site was forehead pre- and 12 hours post-phototherapy with mean difference of 2.15±2.1 mg/dl and\u00000.6±2.13 mg/dl respectively, while sternum was favored site at 24 hours post-phototherapy; with mean difference of\u00002.01±2.32 mg/dl.TCB cut-off values (13.75mg/dl) demonstrated sensitivity (78.5%) and specificity (64.5%) for\u0000discontinuing phototherapy (ROC AUC 0.774, p<0.05). TCB proves effective as a non-invasive screenin Conclusion: g\u0000tool for bilirubin estimation, alleviating the need for repeated blood draws. However, caution is advised regarding TCB's\u0000reliability during phototherapy monitoring. The study provides valuable insights into TCB's clinical applicability,\u0000offering practical recommendations for optimal usage.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"85 3-4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/8303885
Komal Paghadar, Rasik N Hathila
Background: Fine needle aspiration cytology (FNAC) is a well-established technique that plays a critical role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6 tier Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) helps standardize reporting systems and may aid in better communication between clinicians and pathologists and guide the clinical management of patients.Aims:We aimed to study the utility of FNAC in the diagnosis of salivary gland lesions and also study the cytomorphological features of various salivary gland lesions using Milan system classification. Methods and Material: We performed a retrospective analysis of salivary gland lesion FNAC in cytopathology department,tertiary care center from January 2018 to May 2019.All the cases of salivary gland aspirates were classified into six diagnostic categories according to the Milan system of reporting salivary gland cytology (MSRSGC) as follows: Category 1: Non-diagnostic (ND); Category 2: Non-neoplastic (NN); Category 3: Atypia of undetermined significance (AUS); Category 4a: Neoplasm: benign (NB), Category 4b: Neoplasm: salivary gland neoplasm of uncertain malignant potential (SUMP);Category 5:suspicious of malignancy (SM);and Category 6:Malignant (M). Results:A total of 54 cases of salivary gland aspirates were classified using the Milan system as non-diagnostic 2 cases (3.7%), non-neoplastic 12 (22.22%), atypia of undetermined significance 1 (1.85%), neoplasm 32 (59.3%), suspicious for malignancy 1 (1.86%), and malignancy 6 (11.1%).Pleomorphic Adenoma (23 cases;43%) was the most common benign salivary gland lesions and Mucoepidermoid Carcinoma (3 cases; 5.6%) was most common malignant lesion. Parotid gland (38 cases; 70.4%) was the most commonly involved in benign and malignant tumors. Commonly affected age group by benign salivary gland lesion was 31-40 years and those with malignant salivary gland lesion was 21-30 years. Conclusions: The MSRSGC helps pathologists to standardize reporting leading to better clinical and surgical management.
{"title":"“CYTOMORPHOLOGICAL STUDY OF VARIOUS SALIVARY GLAND LESIONS AND EVALUATION BY MILAN SYSTEM FOR REPORTING SALIVARY GLAND CYTOPATHOLOGY IN TERTIARY CARE CENTRE”","authors":"Komal Paghadar, Rasik N Hathila","doi":"10.36106/paripex/8303885","DOIUrl":"https://doi.org/10.36106/paripex/8303885","url":null,"abstract":"Background: Fine needle aspiration cytology (FNAC) is a well-established technique that plays a critical role in\u0000preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and\u0000cytomorphology overlap, a uniform 6 tier Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) helps\u0000standardize reporting systems and may aid in better communication between clinicians and pathologists and guide the\u0000clinical management of patients.Aims:We aimed to study the utility of FNAC in the diagnosis of salivary gland lesions\u0000and also study the cytomorphological features of various salivary gland lesions using Milan system classification.\u0000Methods and Material: We performed a retrospective analysis of salivary gland lesion FNAC in cytopathology\u0000department,tertiary care center from January 2018 to May 2019.All the cases of salivary gland aspirates were classified\u0000into six diagnostic categories according to the Milan system of reporting salivary gland cytology (MSRSGC) as follows:\u0000Category 1: Non-diagnostic (ND); Category 2: Non-neoplastic (NN); Category 3: Atypia of undetermined significance\u0000(AUS); Category 4a: Neoplasm: benign (NB), Category 4b: Neoplasm: salivary gland neoplasm of uncertain malignant\u0000potential (SUMP);Category 5:suspicious of malignancy (SM);and Category 6:Malignant (M). Results:A total of 54 cases\u0000of salivary gland aspirates were classified using the Milan system as non-diagnostic 2 cases (3.7%), non-neoplastic 12\u0000(22.22%), atypia of undetermined significance 1 (1.85%), neoplasm 32 (59.3%), suspicious for malignancy 1 (1.86%),\u0000and malignancy 6 (11.1%).Pleomorphic Adenoma (23 cases;43%) was the most common benign salivary gland lesions\u0000and Mucoepidermoid Carcinoma (3 cases; 5.6%) was most common malignant lesion. Parotid gland (38 cases; 70.4%)\u0000was the most commonly involved in benign and malignant tumors. Commonly affected age group by benign salivary\u0000gland lesion was 31-40 years and those with malignant salivary gland lesion was 21-30 years. Conclusions: The\u0000MSRSGC helps pathologists to standardize reporting leading to better clinical and surgical management.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"12 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/0600627
Shilpa N. Chitlange, Kumud N Harley, Shamali A. Jungare
Background Dyslipidemia is frequently have lipoprotein abnormalities such as low HDL-C concentrations, increased remnant particles and hypertriglyceridemia. HDL-C concentrations are inversely correlated with atherogenic risk. PON-1 activity was lower in patients with renal insufficiency Aim & Objectives 1) To evaluate activity of PON-1 activity in patients with CRF during pre- and post- hemodialysis sessions 2) To establish interrelationships if any,between PON-1,blood urea and serum creatinine levels. 3) To identify the association of PON -1 with serum HDL levels among CRF patients Materials And Methods Hospital based case-control study consists of 40 patients who were receiving Hemodialysis (HD) therapy in the dialysis unit. Study designed to evaluate alterations in serum PON -1 activity in patients during pre and post dialysis sessions in CRF. Result About 17% increase in the activities of PON-1 have been evident during posthemodialysis as compared to pre-hemodialysis samples of patients with CRF.The mean activity of PON-1 and HDL were decreased in pre-hemodialysis samples of patients with CRF. PON-1 activity and HDL was increased in CRF patients during post-hemodialysis as compared to pre-hemodialysis sessions. In both, the results were statistically highly significant (p < 0.001).There is a positive correaltion between HDL and PON 1. Conclusion This study demonstrates that there is an increased risk of cardiovascular complications in patients undergoing hemodialysis. CRF patients undergoing hemodialysis show an increased generation of reactive oxygen species accompanied by an altered lipid profile and paraoxonase-1.
{"title":"EXPLORING OF SERUM PON 1 ACTIVITY AND ITS ASSOCIATION WITH HDL IN PRE AND POST DIALYSIS CRF PATIENTS : A COMPARATIVE STUDY","authors":"Shilpa N. Chitlange, Kumud N Harley, Shamali A. Jungare","doi":"10.36106/paripex/0600627","DOIUrl":"https://doi.org/10.36106/paripex/0600627","url":null,"abstract":"Background Dyslipidemia is frequently have lipoprotein abnormalities such as low HDL-C concentrations, increased\u0000remnant particles and hypertriglyceridemia. HDL-C concentrations are inversely correlated with atherogenic risk.\u0000PON-1 activity was lower in patients with renal insufficiency\u0000Aim & Objectives\u00001) To evaluate activity of PON-1 activity in patients with CRF during pre- and post- hemodialysis sessions\u00002) To establish interrelationships if any,between PON-1,blood urea and serum creatinine levels.\u00003) To identify the association of PON -1 with serum HDL levels among CRF patients\u0000Materials And Methods Hospital based case-control study consists of 40 patients who were receiving Hemodialysis\u0000(HD) therapy in the dialysis unit. Study designed to evaluate alterations in serum PON -1 activity in patients during pre\u0000and post dialysis sessions in CRF. Result About 17% increase in the activities of PON-1 have been evident during posthemodialysis as compared to pre-hemodialysis samples of patients with CRF.The mean activity of PON-1 and HDL were\u0000decreased in pre-hemodialysis samples of patients with CRF. PON-1 activity and HDL was increased in CRF patients\u0000during post-hemodialysis as compared to pre-hemodialysis sessions. In both, the results were statistically highly\u0000significant (p < 0.001).There is a positive correaltion between HDL and PON 1. Conclusion This study demonstrates that\u0000there is an increased risk of cardiovascular complications in patients undergoing hemodialysis. CRF patients\u0000undergoing hemodialysis show an increased generation of reactive oxygen species accompanied by an altered lipid\u0000profile and paraoxonase-1.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"23 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.36106/paripex/7000308
Kunj Pandya, Dhruvin Bhatt, Chirag Dewani
This abstract focuses on the radiological aspects of Amyloid Arthropathy, a condition marked by amyloid protein deposition in joints. Through an analysis of various imaging modalities such as X-ray and USG. the abstract elucidates characteristic findings, emphasizing their significance in diagnosis and disease monitoring. Additionally, it explores the challenges posed by the often subtle radiological features and suggests potential advancements in imaging techniques for enhanced sensitivity. A comprehensive understanding of the radiological manifestations of Amyloid Arthropathy is essential for accurate diagnosis and optimal patient management.
淀粉样蛋白关节病是一种以淀粉样蛋白在关节中沉积为特征的疾病。通过对 X 光和 USG 等各种成像模式的分析，摘要阐明了这些发现的特点，强调了它们在诊断和疾病监测中的重要性。此外，摘要还探讨了往往很微妙的放射学特征所带来的挑战，并提出了提高灵敏度的成像技术的潜在进步。全面了解淀粉样变性关节病的放射学表现对于准确诊断和优化患者管理至关重要。
{"title":"A CASE REPORT ON AMYLOID ARTHROPATHY","authors":"Kunj Pandya, Dhruvin Bhatt, Chirag Dewani","doi":"10.36106/paripex/7000308","DOIUrl":"https://doi.org/10.36106/paripex/7000308","url":null,"abstract":"This abstract focuses on the radiological aspects of Amyloid Arthropathy, a condition marked by amyloid protein\u0000deposition in joints. Through an analysis of various imaging modalities such as X-ray and USG. the abstract elucidates\u0000characteristic findings, emphasizing their significance in diagnosis and disease monitoring. Additionally, it explores the\u0000challenges posed by the often subtle radiological features and suggests potential advancements in imaging techniques\u0000for enhanced sensitivity. A comprehensive understanding of the radiological manifestations of Amyloid Arthropathy is\u0000essential for accurate diagnosis and optimal patient management.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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