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Association between weekend catch-up sleep and white blood cell count among Korean adults: A population-based cross-sectional study 韩国成年人周末补觉与白细胞计数之间的关系:一项基于人群的横断面研究
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-25 DOI: 10.1016/j.ypmed.2025.108474
Juyeon Lee , Ye-Jee Kim , Bo Ram Yang

Objective

This study investigated the association between weekend catch-up sleep (WCS) and systemic inflammation, as indicated by serum white blood cell (WBC) counts.

Methods

A cross-sectional study of 22,143 participants from the Korea National Health and Nutrition Examination Survey (2016–2018, and 2021) categorized into no-WCS (<1 h), moderate WCS (1 to <3 h), and extended WCS (≥3 h). WBC counts were divided into quartiles, and polytomous logistic regression was used to assess associations between WCS and WBC counts. Stratified analyses considered age, sex, body mass index (BMI), sleep duration, and bedtime inconsistency.

Results

Extended WCS was modestly associated with higher WBC counts, particularly in adults aged 20–39 years (odds ratio [OR] = 1.42, 95 % confidence interval [CI]: 1.08, 1.87), 40–64 years (OR = 1.54, 95 % CI: 1.19, 1.99), males (OR = 1.56, 95 %e CI: 1.21, 2.01), individuals with BMI < 25 kg/m2 (OR = 1.45, 95 % CI: 1.21, 1.76), and those with irregular bedtimes (OR = 1.78, 95 % CI: 1.34, 2.37). Moderate WCS was inversely associated with higher BMI (OR = 0.79, 95 % CI: 0.64, 0.97). Significant interactions were observed by age, sex, BMI, and bedtime inconsistency.

Conclusions

Extended WCS was associated with elevated systemic inflammation in specific subgroups. Maintaining regular and moderate sleep patterns may help mitigate low-grade inflammation.
目的研究周末补觉(WCS)与全身炎症之间的关系,并通过血清白细胞(WBC)计数进行分析。方法对来自韩国国家健康与营养调查(2016-2018年和2021年)的22143名参与者进行横断面研究,分为无WCS(1小时)、中度WCS(1至3小时)和延长WCS(≥3小时)。白细胞计数被分成四分位数,并使用多分逻辑回归来评估白细胞计数与白细胞计数之间的关系。分层分析考虑了年龄、性别、身体质量指数(BMI)、睡眠时间和就寝时间不一致。结果WCS延长与白细胞计数升高有一定的相关性,特别是在20-39岁的成年人(优势比[OR] = 1.42, 95%可信区间[CI]: 1.08, 1.87)、40-64岁的成年人(OR = 1.54, 95% CI: 1.19, 1.99)、男性(OR = 1.56, 95% CI: 1.21, 2.01)、BMI = 25 kg/m2的个体(OR = 1.45, 95% CI: 1.21, 1.76)和就寝时间不规律的个体(OR = 1.78, 95% CI: 1.34, 2.37)。中度WCS与较高的BMI呈负相关(OR = 0.79, 95% CI: 0.64, 0.97)。年龄、性别、BMI和就寝时间不一致观察到显著的相互作用。结论在特定亚组中,WCS延长与全身炎症升高相关。保持规律和适度的睡眠模式可能有助于减轻轻度炎症。
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引用次数: 0
Weight discrimination and up-to-date breast and cervical cancer screening in US women 体重歧视和最新的美国妇女乳腺癌和宫颈癌筛查。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-22 DOI: 10.1016/j.ypmed.2025.108470
Mary A. Gerend , Lucille J. Wilkinson , Chandler Pendleton , Angelina R. Sutin , Janet E. Shepherd

Objective

Little research has investigated whether people's experiences with weight-related discrimination serve as a barrier to cancer screening. This study examined the association between weight discrimination and receipt of up to date (UTD) cervical and breast cancer screening in a demographically diverse sample of US women with representation across the body mass index (BMI) spectrum.

Methods

In 2021, women aged 25–64 years completed an online survey. Multivariable logistic regression assessed the association between perceived weight discrimination (as measured by the Stigmatizing Situations Survey-Brief) and self-reported cervical (N = 909) and breast cancer screening (N = 442), in Black and White women, adjusting for BMI and demographic characteristics.

Results

Among White women, more frequent exposure to weight discrimination was associated with significantly lower odds of UTD cervical cancer screening, AOR = 0.78; 95 % CI = 0.62, 0.97, and breast cancer screening, AOR = 0.53, 95 % CI = 0.36, 0.78; for each unit increase on the weight discrimination scale, the odds of screening decreased by approximately 25–50 %. In contrast, weight discrimination was not significantly associated with either type of screening among Black women.

Conclusions

Previous experiences with weight discrimination may deter some women from seeking routine cancer screening. Strategies for mitigating the harmful consequences of weight-related discrimination in health care settings are needed.
目的:很少有研究调查人们的体重相关歧视经历是否会成为癌症筛查的障碍。本研究调查了体重歧视与接受最新(UTD)宫颈癌和乳腺癌筛查之间的关系,研究对象是人口统计学上不同的美国女性,她们的身体质量指数(BMI)各不相同。方法:2021年,年龄在25-64岁 的女性完成在线调查。多变量逻辑回归评估了黑人和白人女性感知体重歧视(通过污名化情况调查简报测量)与自我报告的宫颈癌(N = 909)和乳腺癌筛查(N = 442)之间的关联,调整了BMI和人口统计学特征。结果:在白人女性中,更频繁地暴露于体重歧视与UTD宫颈癌筛查的几率显著降低相关,AOR = 0.78;95 % CI = 0.62,0.97,乳腺癌筛查,AOR = 0.53,95 % CI = 0.36,0.78;体重歧视量表上每增加一个单位,筛查的几率就下降大约25-50 %。相比之下,在黑人女性中,体重歧视与两种筛查方式都没有显著关联。结论:以往体重歧视的经历可能会阻止一些女性寻求常规的癌症筛查。需要制定战略,减轻保健环境中与体重有关的歧视的有害后果。
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引用次数: 0
Cumulative supplemental nutrition assistance program participation and memory aging among US older adults, 1996–2018 1996-2018年美国老年人累积补充营养援助计划参与与记忆老化
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-22 DOI: 10.1016/j.ypmed.2025.108472
Xuexin Yu , Katrina L. Kezios , Peiyi Lu , Samuel L. Swift , Adina Zeki Al Hazzouri

Objective

Losing Supplemental Nutrition Assistance Program (SNAP) benefits is common and can be stressful. We evaluated cumulative SNAP participation in relation to subsequent memory aging among older adults.

Methods

Data were from 2633 adults aged 65+ in US Health and Retirement Study 1996–2018. Cumulative SNAP participation over the eight-year period was measured as the percentage of the time individuals participated in SNAP when they were eligible and operationalized as never (n = 2257), intermittent (<2/3, n = 219), and sustained (≥2/3, n = 157). Memory function was assessed by composite memory z-scores incorporating direct and proxy assessments. We fit mixed-effects linear regression models to investigate the association of interest.

Results

Compared to those who were eligible but never participated in SNAP, individuals with intermittent (0.017 SD units; 95 % CI: −0.002 to 0.036) and sustained SNAP participation (0.020 SD units; 95 % CI: 0.001 to 0.040) experienced a slower rate of memory decline, although the estimate for the intermittent SNAP group crossed the null. The observed effect size was equivalent to delaying memory decline by 1.87 and 2.24 years per decade for SNAP intermittent and sustained participants.

Conclusion

Cumulative SNAP participation may help to preserve memory health among low-income older adults in the United States.
目的:失去补充营养援助计划(SNAP)的好处是常见的,可以压力。我们评估了累积SNAP参与与老年人随后记忆老化的关系。方法:数据来自1996-2018年美国健康与退休研究的2633名65岁以上成年人。8年期间的累积SNAP参与以个人参与SNAP的时间百分比来衡量,当他们符合条件并被操作为从未( = 2257),间歇性(结果:与那些符合条件但从未参加SNAP的人相比,间歇性(0.017 SD单位;95 % CI: -0.002至0.036)和持续SNAP参与(0.020 SD单位;95 % CI: 0.001至0.040)经历了较慢的记忆衰退速度,尽管间歇性SNAP组的估计超过了零。观察到的效应大小相当于SNAP间歇性和持续性参与者每十年延迟1.87和2.24 年的记忆衰退。结论:累积参与SNAP可能有助于保持美国低收入老年人的记忆健康。
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引用次数: 0
Cancer screening uptake among refugees in high and middle-income countries: a systematic review 高收入和中等收入国家难民接受癌症筛查的情况:系统回顾。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-19 DOI: 10.1016/j.ypmed.2025.108469
Fantu Mamo Aragaw , Angela Dawson , Peter Lekkas , Sarah Yeo , Yan Cheng , Temesgen Muchie Ewunie , Andrew Hayen

Objective

Cancer screening is a crucial strategy for reducing cancer morbidity and mortality. Refugees encounter disproportionate challenges in preventive healthcare, yet their cancer screening uptake remain poorly characterized. We aimed to synthesize breast, cervical, and colorectal cancer screening uptake among refugees in high and middle-income countries.

Method

A systematic search was conducted using OVID (Medline, Embase), CINAHL, Web of Science, and Scopus from inception to July 2024 to identify studies reporting breast, cervical, and colorectal cancer screening uptake among refugees. Articles were screened in Covidence, and methodological quality was assessed using the Joanna Briggs Institute checklist. Data were synthesized with a descriptive and narrative approach.

Result

Of 2044 articles retrieved, 23 studies included in the review. Refugees exhibited lower cervical, breast, and colorectal cancer screening uptake than non-refugees with variation across cancer types. Reported rates of ever having Pap test and mammogram among refugee women ranged from 13.9 % to 59 %, and 5.3 % to 63 %, respectively. Commonly cited determinants of cancer screening uptake included education, length of stay, cultural/religious beliefs, and family/provider recommendations.

Conclusion

Refugees had lower cancer screening uptake than host populations. Targeted, culturally informed multilevel interventions addressing their unique barriers are needed to improve refugees access to cancer screening.
目的:癌症筛查是降低癌症发病率和死亡率的重要策略。难民在预防保健方面遇到了不成比例的挑战,但他们的癌症筛查情况仍然很差。我们的目的是综合高收入和中等收入国家难民的乳腺癌、宫颈癌和结直肠癌筛查情况。方法:系统检索OVID (Medline, Embase), CINAHL, Web of Science和Scopus从成立到2024年7月,以确定报告难民中乳腺癌,宫颈癌和结直肠癌筛查的研究。在《covid - ence》中筛选文章,并使用乔安娜布里格斯研究所的检查表评估方法质量。数据以描述性和叙述性的方法合成。结果:在检索到的2044篇文章中,有23篇研究被纳入综述。与非难民相比,难民的宫颈癌、乳腺癌和结直肠癌筛查率较低,癌症类型存在差异。据报道,难民妇女曾经接受巴氏试验和乳房x光检查的比率分别为13.9 %至59 %和5.3 %至63 %。通常被引用的癌症筛查的决定因素包括教育程度、住院时间、文化/宗教信仰和家庭/提供者建议。结论:难民接受癌症筛查的比例低于东道国人口。有针对性的、了解文化的多层次干预措施需要解决其独特的障碍,以改善难民获得癌症筛查的机会。
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引用次数: 0
Visual disabilities and depression/anxiety among adolescents: A nationwide cohort study 青少年的视觉障碍和抑郁/焦虑:一项全国性队列研究。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-19 DOI: 10.1016/j.ypmed.2025.108468
Zhaoyan Piao , Hee Kyoung Choi , Boyoung Jeon , Euna Han

Objectives

Using South Korea's National Health Insurance Service data (2010−2022), this cohort study compared the risk of depression and anxiety in adolescents with visual disabilities to matched controls, examining the effects of disability severity and duration.

Methods

The study included a cohort of adolescents aged 6–17, consisting of 1444 individuals with visual disabilities and 1444 matched controls. The risks for developing depression and anxiety were assessed using multivariable Cox regression analysis, allowing for the adjustment of covariates.

Results

The incidence of depression was 16.62 % in adolescents with visual disabilities versus 12.12 % in matched controls, while anxiety incidence was 20.64 % versus 16.20 %. After adjustment, adolescents with visual disabilities had a higher risk of depression (adjusted Hazard Ratio [aHR]: 1.35, 95 % CI: 1.11, 1.65) and anxiety (aHR: 1.29, 95 % CI: 1.08, 1.53). Severe visual disability was associated with both conditions. A shorter disability duration (0–3 years) heightened depression risk, whereas a longer duration (≥6 years) was linked to increased anxiety risk.

Conclusions

Visual disability severity and duration are significant determinants of mental health in adolescents. These results highlight a critical need for proactive screening and tailored psychological support to address the specific challenges faced by this vulnerable population.
目的:使用韩国国民健康保险服务(2010-2022)的数据,本队列研究比较了视力障碍青少年与匹配对照组的抑郁和焦虑风险,检查残疾严重程度和持续时间的影响。方法:研究纳入了一组6-17岁的青少年,包括1444名视力障碍个体和1444名匹配的对照组。采用多变量Cox回归分析评估发生抑郁和焦虑的风险,允许调整协变量。结果:视力障碍青少年抑郁发生率为16.62 %,对照组为12.12 %;焦虑发生率为20.64 %,对照组为16.20 %。调整后,有视觉障碍的青少年有更高的抑郁风险(调整后的危险比[aHR]: 1.35, 95 % CI: 1.11, 1.65)和焦虑风险(aHR: 1.29, 95 % CI: 1.08, 1.53)。严重的视力障碍与这两种情况有关。较短的残疾持续时间(0-3 年)会增加抑郁风险,而较长的残疾持续时间(≥6 年)会增加焦虑风险。结论:视力障碍的严重程度和持续时间是青少年心理健康的重要决定因素。这些结果强调了积极筛查和量身定制的心理支持的迫切需要,以解决这一弱势群体面临的具体挑战。
{"title":"Visual disabilities and depression/anxiety among adolescents: A nationwide cohort study","authors":"Zhaoyan Piao ,&nbsp;Hee Kyoung Choi ,&nbsp;Boyoung Jeon ,&nbsp;Euna Han","doi":"10.1016/j.ypmed.2025.108468","DOIUrl":"10.1016/j.ypmed.2025.108468","url":null,"abstract":"<div><h3>Objectives</h3><div>Using South Korea's National Health Insurance Service data (2010−2022), this cohort study compared the risk of depression and anxiety in adolescents with visual disabilities to matched controls, examining the effects of disability severity and duration.</div></div><div><h3>Methods</h3><div>The study included a cohort of adolescents aged 6–17, consisting of 1444 individuals with visual disabilities and 1444 matched controls. The risks for developing depression and anxiety were assessed using multivariable Cox regression analysis, allowing for the adjustment of covariates.</div></div><div><h3>Results</h3><div>The incidence of depression was 16.62 % in adolescents with visual disabilities versus 12.12 % in matched controls, while anxiety incidence was 20.64 % versus 16.20 %. After adjustment, adolescents with visual disabilities had a higher risk of depression (adjusted Hazard Ratio [aHR]: 1.35, 95 % CI: 1.11, 1.65) and anxiety (aHR: 1.29, 95 % CI: 1.08, 1.53). Severe visual disability was associated with both conditions. A shorter disability duration (0–3 years) heightened depression risk, whereas a longer duration (≥6 years) was linked to increased anxiety risk.</div></div><div><h3>Conclusions</h3><div>Visual disability severity and duration are significant determinants of mental health in adolescents. These results highlight a critical need for proactive screening and tailored psychological support to address the specific challenges faced by this vulnerable population.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"202 ","pages":"Article 108468"},"PeriodicalIF":3.2,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental health emergencies and mortality following public fine particulate matter alerts: A Nationwide case-crossover study in South Korea 公共细颗粒物警报后的精神卫生突发事件和死亡率:韩国全国病例交叉研究
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-14 DOI: 10.1016/j.ypmed.2025.108467
Hoyol Jhang , Whanhee Lee , Jong Tae Lee , Yoonhee Kim , Chul-Hyun Cho , Soojung Kim , Seung-Ah Choe

Objective

Little is known about whether issuing particulate matter ≤2.5 μm (PM2.5) alerts influences emergency department presentations for mental health or mortality. We evaluated the impact of PM2.5 alerts on mental disorder-related emergency visit and mortality.

Methods

We conducted a time-stratified case-crossover analysis comparing PM2.5 alert versus non-alert days between 1 January 2015 and 31 December 2021 using multiple South Korean databases. Alert days were 1:1 matched to non-alert days on the basis of daily mean municipal-level of PM2.5. We applied conditional Poisson regression models, stratified by region, to estimate relative risks of mental disorder, related emergency department visits and mortality for PM2.5 alert.

Results

A 20 μg/m3 increase in PM2.5 was associated with elevated risks of mental disorder-related emergency department visits and mortality. On PM2.5 alert days, the risk of mental disorder-related emergency visits was lower compared with matched non-alert days (RR = 0.94, 95 % confidence intervals [CI]: 0.92, 0.97). This association was observed for both organic and non-organic mental disorders. All-cause, cardiovascular, and respiratory mortality showed small, non-significant increases on alert days.

Conclusions

Issuance of PM2.5 alerts in South Korea was associated with a modest reduction in emergency visits for mental disorders but did not correspond with lower mortality.
目的:发布≤2.5 μm (PM2.5)的颗粒物警报是否会影响急诊室的心理健康报告或死亡率,目前尚不清楚。我们评估了PM2.5警报对精神障碍相关急诊就诊和死亡率的影响。方法:我们使用多个韩国数据库,对2015年1月1日至2021年12月31日PM2.5警报日与非警报日进行了时间分层病例交叉分析。以全市PM2.5日均值为基础,预警日与非预警日的匹配比例为1:1。我们应用按地区分层的条件泊松回归模型来估计PM2.5警报时精神障碍、相关急诊就诊和死亡率的相对风险。结果:PM2.5每增加20 μg/m3,与精神障碍相关的急诊就诊和死亡风险升高相关。在PM2.5警戒日,与非警戒日相比,精神障碍相关急诊就诊的风险较低(RR = 0.94,95 %可信区间[CI]: 0.92, 0.97)。器质性和非器质性精神障碍均观察到这种关联。在警戒日,全因死亡率、心血管死亡率和呼吸系统死亡率均有小幅、不显著的增加。结论:在韩国,PM2.5警报的发布与精神障碍急诊人数的适度减少有关,但与较低的死亡率无关。
{"title":"Mental health emergencies and mortality following public fine particulate matter alerts: A Nationwide case-crossover study in South Korea","authors":"Hoyol Jhang ,&nbsp;Whanhee Lee ,&nbsp;Jong Tae Lee ,&nbsp;Yoonhee Kim ,&nbsp;Chul-Hyun Cho ,&nbsp;Soojung Kim ,&nbsp;Seung-Ah Choe","doi":"10.1016/j.ypmed.2025.108467","DOIUrl":"10.1016/j.ypmed.2025.108467","url":null,"abstract":"<div><h3>Objective</h3><div>Little is known about whether issuing particulate matter ≤2.5 μm (PM<sub>2.5</sub>) alerts influences emergency department presentations for mental health or mortality. We evaluated the impact of PM<sub>2.5</sub> alerts on mental disorder-related emergency visit and mortality.</div></div><div><h3>Methods</h3><div>We conducted a time-stratified case-crossover analysis comparing PM<sub>2.5</sub> alert versus non-alert days between 1 January 2015 and 31 December 2021 using multiple South Korean databases. Alert days were 1:1 matched to non-alert days on the basis of daily mean municipal-level of PM<sub>2.5</sub>. We applied conditional Poisson regression models, stratified by region, to estimate relative risks of mental disorder, related emergency department visits and mortality for PM<sub>2.5</sub> alert.</div></div><div><h3>Results</h3><div>A 20 μg/m<sup>3</sup> increase in PM<sub>2.5</sub> was associated with elevated risks of mental disorder-related emergency department visits and mortality. On PM<sub>2.5</sub> alert days, the risk of mental disorder-related emergency visits was lower compared with matched non-alert days (RR = 0.94, 95 % confidence intervals [CI]: 0.92, 0.97). This association was observed for both organic and non-organic mental disorders. All-cause, cardiovascular, and respiratory mortality showed small, non-significant increases on alert days.</div></div><div><h3>Conclusions</h3><div>Issuance of PM<sub>2.5</sub> alerts in South Korea was associated with a modest reduction in emergency visits for mental disorders but did not correspond with lower mortality.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"202 ","pages":"Article 108467"},"PeriodicalIF":3.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Whole School Food Approach: A European framework and implementation to promote healthy and sustainable school food systems 整个学校食品方法:促进健康和可持续学校食品系统的欧洲框架和实施。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-11 DOI: 10.1016/j.ypmed.2025.108440
Irene Vidal , Katharina Beelen , Annelies Smets , Monika Rut , Evelin Piirsalu , Julia Diez , Manuel Franco

Objective

We describe the development of the Whole School Food Approach framework and its implementation in 12 European countries participating in the European-funded project, SchoolFood4Change.

Methods

The framework was developed in 2022 by a multidisciplinary team following an evidence-based approach. Data on implementation criteria were collected through mixed-methods in schools between 2022 and 2025 in 17 cities. Surveys with national project coordinators assessed achievement of bronze-level criteria for each framework component. Implementation scores were calculated based on the number of bronze criteria achieved. Semi-structured interviews with city representatives explored perceptions, challenges, and enablers of implementation.

Results

The framework comprised four interrelated components and three scalable levels of progress: bronze, silver, and gold. To date, 549 schools have implemented it. Online surveys from participating cities and schools (n = 109) showed diverse levels of implementation across schools, with 21 achieving bronze-level. Semi-structured interviews (n = 16) identified cross-departmental collaboration, staff capacity, and time availability as main barriers. Political and institutional support was reported as the main facilitator for promoting school food policies.

Conclusions

Findings showed a diverse implementation of the framework in participating European countries. Despite challenges, the Whole School Food Approach was perceived as a valuable tool for developing healthy and sustainable school food systems.
目的:我们描述了整个学校食物方法(WSFA)框架的发展及其在参与欧洲资助项目SchoolFood4Change的12个欧洲国家的实施情况。方法:该框架于2022年由一个多学科团队按照循证方法开发。在2022年至2025年期间,通过混合方法收集了17个城市学校执行标准的数据。与国家项目协调员进行的调查评估了每个框架组成部分的铜质标准的实现情况。执行分数是根据达到的铜质标准的数量计算的。与城市代表进行的半结构化访谈探讨了实施的看法、挑战和推动因素。结果:该框架包括四个相互关联的组成部分和三个可扩展的进展水平:铜牌、银牌和金牌。迄今为止,已有549所学校实施了该计划。参与调查的城市和学校(n = 109)的在线调查显示,各学校的实施水平参差不齐,有21所学校达到铜牌水平。半结构化访谈(n = 16)确定跨部门协作、员工能力和时间可用性是主要障碍。据报告,政治和体制支持是促进学校食品政策的主要促进因素。结论:调查结果显示,参与的欧洲国家对该框架的实施情况多种多样。尽管面临挑战,WSFA仍被视为发展健康和可持续学校食品系统的宝贵工具。
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引用次数: 0
Induced abortion rates among women vaccinated against human papillomavirus: Registry-based follow-up of a community-randomized trial 接种人乳头瘤病毒疫苗妇女的人工流产率:基于登记的社区随机试验随访
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-10 DOI: 10.1016/j.ypmed.2025.108441
Kaisa Taavela , Tiina Koivisto , Tiina Eriksson , Dan Apter , Matti Lehtinen , Karolina Louvanto

Objective

Concerns have been raised that human papillomavirus (HPV)-vaccination programs may alter risk perceptions and increase risk-taking sexual behavior among adolescents. This study aimed to assess induced abortion rates (as a potential indicator of such behavior) between vaccinated and unvaccinated individuals.

Methods

This longitudinal, cluster-randomized cohort study included 6200 HPV-vaccinated women born in 1992–1993 who participated in a 2007 launched HPV-vaccination trial in Finland, and 19,473 unvaccinated women born in 1990–1991 from the same communities. Registry data from a 12-year follow-up period (between 2007 and 2020, depending on the group) up to the age of 28 years was obtained from The Finnish Register on Induced Abortions.

Results

Incidence rate of induced abortions per 10,000 person-years was significantly lower among HPV-vaccinated (145.6(95 %CI 137.1,154.5)) compared to unvaccinated individuals (161.4(95 %CI 156.4,166.7)). HPV-vaccinated individuals induced abortions in earlier gestational weeks (p = 0.049). Up to four-years post sexual health education given at HPV vaccination visits, induced abortion rates were significantly lower among individuals aged 15–19 (33.7(95 %CI 29.8,38.2)) than age-aligned unvaccinated controls (42.4(95 %CI 38.9,44.1)).

Conclusions

HPV-vaccinated had lower induced abortion rates than unvaccinated individuals. When further developing HPV-vaccination programs, simultaneous sexual health education should be considered to comprehensively improve the reproductive health of adolescents.
目的:人们越来越担心人乳头瘤病毒(HPV)疫苗接种计划可能会改变青少年的风险认知并增加冒险的性行为。本研究旨在评估接种疫苗和未接种疫苗的个体之间的人工流产率(作为这种行为的潜在指标)。方法:这项纵向、集群随机队列研究包括6200名1992-1993年出生的hpv疫苗接种妇女,她们参加了2007年在芬兰开展的hpv疫苗接种试验,以及来自同一社区的19473名1990-1991年出生的未接种hpv疫苗的妇女。从芬兰人工流产登记处获得了12年随访期(2007年至2020年,取决于分组)至28 岁的登记数据。结果:hpv疫苗接种人群的人工流产发生率(145.6(95 %CI 137.1154.5)显著低于未接种人群(161.4(95 %CI 156.4166.7))。接种hpv疫苗的个体在妊娠早期流产(p = 0.049)。在HPV疫苗接种就诊时进行性健康教育四年后,15-19岁人群的人工流产率(33.7(95 %CI 29.8,38.2)显著低于同龄未接种疫苗的对照组(42.4(95 %CI 38.9,44.1))。结论:hpv疫苗接种者的人工流产率低于未接种者。在进一步开展hpv疫苗接种规划时,应同时考虑性健康教育,全面提高青少年的生殖健康水平。
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引用次数: 0
Tobacco use and eligibility for lung cancer screening among dental patients at an academic institution in Houston, Texas 在德克萨斯州休斯顿的一个学术机构中,牙科患者的烟草使用和肺癌筛查的资格。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-08 DOI: 10.1016/j.ypmed.2025.108438
Ana S. Neumann , Iakovos Toumazis , Jennifer A. O'Brien , Diane Beneventi , Sai Keerthi Annam , Anita Joy-Thomas , Robert J. Volk

Objective

Tobacco use negatively impacts oral and general health and influences dental treatment outcomes. To advance prevention, we surveyed dental patients at an academic institution to characterize their history of tobacco use and eligibility for lung cancer screening (LCS).

Methods

Anonymous surveys were administered to adult dental patients at the UTHealth Houston School of Dentistry between April 2022 and October 2022. Surveys collected information on smoking history, pack-year history, health literacy, personal and family history of lung cancer, and previous LCS. Demographic variables included age, gender, race/ethnicity, and education level.

Results

Among 432 patients (mean age: 46.4, range 18–88 years, 57.0 % female), 22.7 % were patients who currently smoked cigarettes, and 13.2 % were patients who formerly smoked. Smoking rates were highest among males (36.2 %) and patients younger than 50 (26.0 %). Among patients who currently smoked, 44.1 % met eligibility for LCS based on age and a 20+ pack-year smoking history; 43.2 % of patients who formerly smoked were eligible for LCS.

Conclusions

A substantial proportion of patients are eligible for LCS; tailored cessation counseling and electronic-referral pathways could impact screening and cessation support for millions of high-risk adults who visit a dentist each year, closing a critical gap in cancer prevention.
目的:烟草使用对口腔和一般健康产生负面影响,并影响牙科治疗结果。为了促进预防,我们调查了一家学术机构的牙科患者,以描述他们的烟草使用史和肺癌筛查(LCS)的资格。方法:对2022年4月至2022年10月期间UTHealth休斯顿牙科学院的成年牙科患者进行匿名调查。调查收集了吸烟史、包年史、健康素养、个人和家族肺癌史以及既往LCS的信息。人口统计变量包括年龄、性别、种族/民族和教育水平。结果:在432例患者中(平均年龄46.4岁,年龄范围18-88 岁,57.0% %为女性),22.7% %为目前吸烟的患者,13.2% %为以前吸烟的患者。男性(36.2% %)和50岁以下患者(26.0% %)吸烟率最高。在目前吸烟的患者中,44.1% %符合基于年龄和20年以上吸烟史的LCS资格;43.2% 以前吸烟的患者符合LCS的条件。结论:相当大比例的患者符合LCS的条件;量身定制的戒烟咨询和电子转诊途径可能会影响每年数百万去看牙医的高风险成年人的筛查和戒烟支持,从而缩小癌症预防方面的重大差距。
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引用次数: 0
Incidence and synergistic Association of Type 2 diabetes and apolipoprotein E epsilon 4 with dementia risk in the Kunshan aging research with E-health cohort study 昆山老龄化研究中2型糖尿病和载脂蛋白E epsilon 4与痴呆风险的发病率及协同关联
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-05 DOI: 10.1016/j.ypmed.2025.108439
Wanqing Dong , Jie Bai , Benrui Wu , Kaixin Zhou , Hongwei Jiang

Objective

To investigate the independent and combined associations of type 2 diabetes (T2D) and APOE genotype on dementia risk.

Methods

We analyzed 104,911 participants aged ≥50 years from the Kunshan Aging Research with E-Health cohort (2018–2024). Incident dementia was identified using electronic medical records. Cox proportional hazards models and additive interaction analyses assessed associations and interactions.

Results

Over a median follow-up of 6.19 years, 8115 participants developed dementia. T2D was associated with higher risks of all-cause dementia (HR:2.06), Alzheimer's disease (HR:2.16), and vascular dementia (HR:1.62). APOE ε4 carriers had higher Alzheimer's risk (HR:1.35), while ε2 carriers had lower risk (HR:0.87). The combination of T2D and ε4 was associated with the highest Alzheimer's risk (HR:2.87) with a significant positive additive interaction. In men, T2D interacted with ε2 on a multiplicative scale, whereas in women, a positive additive interaction was observed between T2D and ε2 for Alzheimer's disease.

Conclusions

T2D was associated with higher dementia risk. APOE ε4 was associated with higher and ε2 with lower Alzheimer's risk. A positive additive T2D–ε4 interaction and sex-specific ε2 associations underscore integrating diabetes management with genetic profiling to optimize dementia risk reduction strategies.
目的:探讨2型糖尿病(T2D)和APOE基因型与痴呆风险的独立和联合关系。方法:我们分析了来自昆山老龄化研究与电子健康队列(2018-2024)的104,911名年龄≥50 岁的参与者。使用电子医疗记录确定偶发性痴呆。Cox比例风险模型和加性相互作用分析评估了关联和相互作用。结果:在中位随访6.19 年期间,8115名参与者患上了痴呆症。T2D与全因痴呆(风险比:2.06)、阿尔茨海默病(风险比:2.16)和血管性痴呆(风险比:1.62)的高风险相关。APOE ε4携带者阿尔茨海默病风险较高(HR:1.35), ε2携带者阿尔茨海默病风险较低(HR:0.87)。T2D和ε4的组合与阿尔茨海默病的最高风险相关(HR:2.87),具有显著的正加性相互作用。在男性中,T2D与ε2以乘法尺度相互作用,而在女性中,观察到T2D和ε2在阿尔茨海默病中呈正加性相互作用。结论:T2D与较高的痴呆风险相关。APOE ε4与较高的阿尔茨海默病风险相关,ε2与较低的阿尔茨海默病风险相关。T2D-ε4正加性相互作用和性别特异性ε2关联强调了将糖尿病管理与基因分析结合起来优化痴呆风险降低策略。
{"title":"Incidence and synergistic Association of Type 2 diabetes and apolipoprotein E epsilon 4 with dementia risk in the Kunshan aging research with E-health cohort study","authors":"Wanqing Dong ,&nbsp;Jie Bai ,&nbsp;Benrui Wu ,&nbsp;Kaixin Zhou ,&nbsp;Hongwei Jiang","doi":"10.1016/j.ypmed.2025.108439","DOIUrl":"10.1016/j.ypmed.2025.108439","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the independent and combined associations of type 2 diabetes (T2D) and APOE genotype on dementia risk.</div></div><div><h3>Methods</h3><div>We analyzed 104,911 participants aged ≥50 years from the Kunshan Aging Research with <em>E</em>-Health cohort (2018–2024). Incident dementia was identified using electronic medical records. Cox proportional hazards models and additive interaction analyses assessed associations and interactions.</div></div><div><h3>Results</h3><div>Over a median follow-up of 6.19 years, 8115 participants developed dementia. T2D was associated with higher risks of all-cause dementia (HR:2.06), Alzheimer's disease (HR:2.16), and vascular dementia (HR:1.62). APOE ε4 carriers had higher Alzheimer's risk (HR:1.35), while ε2 carriers had lower risk (HR:0.87). The combination of T2D and ε4 was associated with the highest Alzheimer's risk (HR:2.87) with a significant positive additive interaction. In men, T2D interacted with ε2 on a multiplicative scale, whereas in women, a positive additive interaction was observed between T2D and ε2 for Alzheimer's disease.</div></div><div><h3>Conclusions</h3><div>T2D was associated with higher dementia risk. APOE ε4 was associated with higher and ε2 with lower Alzheimer's risk. A positive additive T2D–ε4 interaction and sex-specific ε2 associations underscore integrating diabetes management with genetic profiling to optimize dementia risk reduction strategies.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"202 ","pages":"Article 108439"},"PeriodicalIF":3.2,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145471802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Preventive medicine
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