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The impact of nutrition information labels on alcohol containers in Canada: an online randomized trial 加拿大酒精容器上营养信息标签的影响:一项在线随机试验
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-25 DOI: 10.1016/j.ypmed.2025.108475
Lana Vanderlee , Christine M. White , David Hammond , Erin Hobin

Objective

To determine if nutritional information on an alcohol container influenced consumer perceptions of product healthiness, and whether the effect of information differed by display format.

Methods

Online randomized controlled trial among adults in Canada sampled from a commercial panel (analytical sample n = 3880) in November/December 2024. Participants were randomized to view a wine product in one of four conditions: (1) control (no label), (2) Nutrition Facts table (NFT), (3) textual nutrition information, (4) Alcohol Facts table, and were asked “How healthy would it be to drink this wine regularly?” (7-point Likert-type item, very unhealthy to very healthy). Logistic regression compared the likelihood of rating the product as “a little healthy/healthy/very healthy” between conditions.

Results

Compared to the control (16.5 %), those in the NFT condition had higher odds of rating the product as “a little healthy/healthy/very healthy” (28.3 %, AOR = 1.97, 95 %CI,1.57,2.47), as did those in the textual nutrition information condition (23.8 %, AOR = 1.60, 95 %CI,1.27,2.02). There were no differences between the control condition and the Alcohol Facts table condition (18.8 %).

Conclusions

Nutritional information on alcohol products may lead consumers to falsely believe products are ‘healthier’. Label design and features that make alcohol products distinct from non-alcoholic food and beverages may reduce unintended impacts.
目的:确定酒精容器上的营养信息是否影响消费者对产品健康的看法,以及信息的效果是否因显示形式而异。方法:于2024年11月/ 12月在加拿大进行成人在线随机对照试验(分析样本n = 3880)。参与者被随机分为四种情况:(1)对照(没有标签),(2)营养成分表(NFT),(3)文字营养信息,(4)酒精成分表,并被问及“经常喝这种酒会有多健康?”(李克特7分项目,非常不健康到非常健康)。逻辑回归比较了在不同条件下将产品评为“有点健康/健康/非常健康”的可能性。结果:与控制(16.5 %)相比,那些非功能性测试条件有更高的几率评级的产品“有点健康/健康/非常健康”(28.3 %,AOR = 1.97,95 % CI, 1.57, 2.47),文本中,营养信息条件(23.8 %,AOR = 1.60,95 % CI, 1.27, 2.02)。对照组与酒精事实组之间无差异(18.8 %)。结论:酒精产品上的营养信息可能导致消费者错误地认为产品“更健康”。将酒精产品与非酒精食品和饮料区分开来的标签设计和特征可以减少意外影响。
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引用次数: 0
The Whole School Food Approach: A European framework and implementation to promote healthy and sustainable school food systems 整个学校食品方法:促进健康和可持续学校食品系统的欧洲框架和实施。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-11 DOI: 10.1016/j.ypmed.2025.108440
Irene Vidal , Katharina Beelen , Annelies Smets , Monika Rut , Evelin Piirsalu , Julia Diez , Manuel Franco

Objective

We describe the development of the Whole School Food Approach framework and its implementation in 12 European countries participating in the European-funded project, SchoolFood4Change.

Methods

The framework was developed in 2022 by a multidisciplinary team following an evidence-based approach. Data on implementation criteria were collected through mixed-methods in schools between 2022 and 2025 in 17 cities. Surveys with national project coordinators assessed achievement of bronze-level criteria for each framework component. Implementation scores were calculated based on the number of bronze criteria achieved. Semi-structured interviews with city representatives explored perceptions, challenges, and enablers of implementation.

Results

The framework comprised four interrelated components and three scalable levels of progress: bronze, silver, and gold. To date, 549 schools have implemented it. Online surveys from participating cities and schools (n = 109) showed diverse levels of implementation across schools, with 21 achieving bronze-level. Semi-structured interviews (n = 16) identified cross-departmental collaboration, staff capacity, and time availability as main barriers. Political and institutional support was reported as the main facilitator for promoting school food policies.

Conclusions

Findings showed a diverse implementation of the framework in participating European countries. Despite challenges, the Whole School Food Approach was perceived as a valuable tool for developing healthy and sustainable school food systems.
目的:我们描述了整个学校食物方法(WSFA)框架的发展及其在参与欧洲资助项目SchoolFood4Change的12个欧洲国家的实施情况。方法:该框架于2022年由一个多学科团队按照循证方法开发。在2022年至2025年期间,通过混合方法收集了17个城市学校执行标准的数据。与国家项目协调员进行的调查评估了每个框架组成部分的铜质标准的实现情况。执行分数是根据达到的铜质标准的数量计算的。与城市代表进行的半结构化访谈探讨了实施的看法、挑战和推动因素。结果:该框架包括四个相互关联的组成部分和三个可扩展的进展水平:铜牌、银牌和金牌。迄今为止,已有549所学校实施了该计划。参与调查的城市和学校(n = 109)的在线调查显示,各学校的实施水平参差不齐,有21所学校达到铜牌水平。半结构化访谈(n = 16)确定跨部门协作、员工能力和时间可用性是主要障碍。据报告,政治和体制支持是促进学校食品政策的主要促进因素。结论:调查结果显示,参与的欧洲国家对该框架的实施情况多种多样。尽管面临挑战,WSFA仍被视为发展健康和可持续学校食品系统的宝贵工具。
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引用次数: 0
Assessing the association between cannabis use frequency and heart disease in adults aged under 50: National Survey on Drug Use and Health, 2021–2023 评估50岁以下成年人大麻使用频率与心脏病之间的关系:2021-2023年全国药物使用和健康调查。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-10-30 DOI: 10.1016/j.ypmed.2025.108437
Mason Earl, Ruchi Bhandari

Objective

Cannabis use has increased among younger adults in the United States alongside rising rates of heart disease. This study examines the association between cannabis use frequency and heart disease among adults aged 18–49.

Methods

A cross-sectional analysis of 88,166 United States adults aged 18–49 was conducted using 2021–2023 National Survey on Drug Use and Health data. Cannabis use frequency was measured as days of cannabis use in the past year. A weighted logistic regression model estimated the adjusted odds ratio (aOR) for heart disease, controlling for demographics, smoking, and heavy drinking. Additionally, A dose-response analysis was performed to further assess the relationship.

Results

Cannabis users had significantly higher odds of heart disease compared to non-users. Each 90-day increase in cannabis use was associated with 9 % higher odds of heart disease (aOR: 1.09; 95 % Confidence Interval: 1.03, 1.15). Daily users had 40 % higher odds of heart disease compared to non-users (aOR = 1.40; 95 % Confidence Interval: 1.11, 1.76). A clear dose-response relationship was observed.

Conclusions

Cannabis use frequency is significantly associated with higher odds of heart disease among US adults under 50. Findings demonstrate a positive linear relationship and indicate cannabis use as a potential modifiable risk factor for early-onset heart disease.
目的:在美国,随着心脏病发病率的上升,大麻的使用在年轻人中有所增加。这项研究调查了18-49岁成年人大麻使用频率与心脏病之间的关系。方法:利用2021-2023年全国药物使用和健康调查数据,对88166名18-49岁的美国成年人进行横断面分析。大麻使用频率以过去一年中使用大麻的天数来衡量。加权逻辑回归模型估计心脏病的调整优势比(aOR),控制人口统计学、吸烟和酗酒。此外,还进行了剂量-反应分析以进一步评估两者之间的关系。结果:与不吸食大麻的人相比,吸食大麻的人患心脏病的几率明显更高。大麻使用每增加90天,患心脏病的几率增加9 % (aOR: 1.09; 95 %可信区间:1.03,1.15)。每日使用者患心脏病的几率比不使用者高40 % (aOR = 1.40;95 %置信区间:1.11,1.76)。观察到明显的剂量-反应关系。结论:大麻使用频率与50岁以下美国成年人患心脏病的几率显著相关。研究结果显示了正线性关系,并表明大麻使用是早发性心脏病的潜在可改变风险因素。
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引用次数: 0
The association between outdoor environmental factors in kindergartens and children's moderate-to-vigorous physical activity: A systematic review and meta-analysis 幼儿园户外环境因素与儿童中高强度体育活动的关系:系统回顾与meta分析
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-25 DOI: 10.1016/j.ypmed.2025.108473
Zilin Xu, Shuting Li, Hui Chu, Kun Zhou

Objectives

The kindergarten outdoor environment is considered a key factor influencing children's moderate-to-vigorous physical activity (MVPA). However, existing findings remain inconsistent, with varying criteria and no synthesis.

Methods

Associations came from studies employing two common measurement methods: accelerometry and direct observation. Fixed- or random-effects models were applied to calculate pooled correlation coefficients. A systematic search of six databases for studies published 2000–2024 identified 17 articles, and 9 met the inclusion criteria for meta-analysis. All outdoor environmental factors were standardized and categorized using validated observational systems, enabling consistent evaluation of their associations with children's MVPA and facilitating data integration across methods.

Results

Open spaces, natural elements, and “ball and object play” were moderately positively associated with children's MVPA. Fixed equipment showed weak positive association, while sedentary environments showed very weak negative association. Direct observation appeared slightly more sensitive than accelerometry in detecting these associations.

Conclusions

Open spaces, natural elements, and “ball and object play” are associated with higher levels of children's MVPA, while sedentary environments are linked to reduced activity. These findings highlight the importance of designing kindergarten outdoor environments that promote children's physical activity and healthy development. Future studies should consider the influence of measurement tool differences on results.
目的:幼儿园室外环境是影响幼儿中高强度体育活动(MVPA)的关键因素。然而,现有的研究结果仍然不一致,标准不一,没有综合。方法采用两种常用的测量方法:加速度测量法和直接观察法。采用固定或随机效应模型计算合并相关系数。对2000-2024年发表的6个数据库进行系统检索,发现17篇文章,其中9篇符合meta分析的纳入标准。使用经过验证的观测系统对所有室外环境因素进行标准化和分类,从而能够对其与儿童MVPA的关联进行一致的评估,并促进跨方法的数据整合。结果开放空间、自然元素和“球与物体游戏”与儿童MVPA呈正相关。固定设备表现出微弱的正相关,而久坐环境表现出非常微弱的负相关。在检测这些关联时,直接观察比加速度计略灵敏。开放空间、自然元素和“球和物体游戏”与儿童MVPA水平较高有关,而久坐环境与活动减少有关。这些发现强调了设计促进儿童身体活动和健康发展的幼儿园户外环境的重要性。未来的研究应考虑测量工具差异对结果的影响。
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引用次数: 0
Induced abortion rates among women vaccinated against human papillomavirus: Registry-based follow-up of a community-randomized trial 接种人乳头瘤病毒疫苗妇女的人工流产率:基于登记的社区随机试验随访
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-10 DOI: 10.1016/j.ypmed.2025.108441
Kaisa Taavela , Tiina Koivisto , Tiina Eriksson , Dan Apter , Matti Lehtinen , Karolina Louvanto

Objective

Concerns have been raised that human papillomavirus (HPV)-vaccination programs may alter risk perceptions and increase risk-taking sexual behavior among adolescents. This study aimed to assess induced abortion rates (as a potential indicator of such behavior) between vaccinated and unvaccinated individuals.

Methods

This longitudinal, cluster-randomized cohort study included 6200 HPV-vaccinated women born in 1992–1993 who participated in a 2007 launched HPV-vaccination trial in Finland, and 19,473 unvaccinated women born in 1990–1991 from the same communities. Registry data from a 12-year follow-up period (between 2007 and 2020, depending on the group) up to the age of 28 years was obtained from The Finnish Register on Induced Abortions.

Results

Incidence rate of induced abortions per 10,000 person-years was significantly lower among HPV-vaccinated (145.6(95 %CI 137.1,154.5)) compared to unvaccinated individuals (161.4(95 %CI 156.4,166.7)). HPV-vaccinated individuals induced abortions in earlier gestational weeks (p = 0.049). Up to four-years post sexual health education given at HPV vaccination visits, induced abortion rates were significantly lower among individuals aged 15–19 (33.7(95 %CI 29.8,38.2)) than age-aligned unvaccinated controls (42.4(95 %CI 38.9,44.1)).

Conclusions

HPV-vaccinated had lower induced abortion rates than unvaccinated individuals. When further developing HPV-vaccination programs, simultaneous sexual health education should be considered to comprehensively improve the reproductive health of adolescents.
目的:人们越来越担心人乳头瘤病毒(HPV)疫苗接种计划可能会改变青少年的风险认知并增加冒险的性行为。本研究旨在评估接种疫苗和未接种疫苗的个体之间的人工流产率(作为这种行为的潜在指标)。方法:这项纵向、集群随机队列研究包括6200名1992-1993年出生的hpv疫苗接种妇女,她们参加了2007年在芬兰开展的hpv疫苗接种试验,以及来自同一社区的19473名1990-1991年出生的未接种hpv疫苗的妇女。从芬兰人工流产登记处获得了12年随访期(2007年至2020年,取决于分组)至28 岁的登记数据。结果:hpv疫苗接种人群的人工流产发生率(145.6(95 %CI 137.1154.5)显著低于未接种人群(161.4(95 %CI 156.4166.7))。接种hpv疫苗的个体在妊娠早期流产(p = 0.049)。在HPV疫苗接种就诊时进行性健康教育四年后,15-19岁人群的人工流产率(33.7(95 %CI 29.8,38.2)显著低于同龄未接种疫苗的对照组(42.4(95 %CI 38.9,44.1))。结论:hpv疫苗接种者的人工流产率低于未接种者。在进一步开展hpv疫苗接种规划时,应同时考虑性健康教育,全面提高青少年的生殖健康水平。
{"title":"Induced abortion rates among women vaccinated against human papillomavirus: Registry-based follow-up of a community-randomized trial","authors":"Kaisa Taavela ,&nbsp;Tiina Koivisto ,&nbsp;Tiina Eriksson ,&nbsp;Dan Apter ,&nbsp;Matti Lehtinen ,&nbsp;Karolina Louvanto","doi":"10.1016/j.ypmed.2025.108441","DOIUrl":"10.1016/j.ypmed.2025.108441","url":null,"abstract":"<div><h3>Objective</h3><div>Concerns have been raised that human papillomavirus (HPV)-vaccination programs may alter risk perceptions and increase risk-taking sexual behavior among adolescents. This study aimed to assess induced abortion rates (as a potential indicator of such behavior) between vaccinated and unvaccinated individuals.</div></div><div><h3>Methods</h3><div>This longitudinal, cluster-randomized cohort study included 6200 HPV-vaccinated women born in 1992–1993 who participated in a 2007 launched HPV-vaccination trial in Finland, and 19,473 unvaccinated women born in 1990–1991 from the same communities. Registry data from a 12-year follow-up period (between 2007 and 2020, depending on the group) up to the age of 28 years was obtained from The Finnish Register on Induced Abortions.</div></div><div><h3>Results</h3><div>Incidence rate of induced abortions per 10,000 person-years was significantly lower among HPV-vaccinated (145.6(95 %CI 137.1,154.5)) compared to unvaccinated individuals (161.4(95 %CI 156.4,166.7)). HPV-vaccinated individuals induced abortions in earlier gestational weeks (<em>p</em> = 0.049). Up to four-years post sexual health education given at HPV vaccination visits, induced abortion rates were significantly lower among individuals aged 15–19 (33.7(95 %CI 29.8,38.2)) than age-aligned unvaccinated controls (42.4(95 %CI 38.9,44.1)).</div></div><div><h3>Conclusions</h3><div>HPV-vaccinated had lower induced abortion rates than unvaccinated individuals. When further developing HPV-vaccination programs, simultaneous sexual health education should be considered to comprehensively improve the reproductive health of adolescents.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"202 ","pages":"Article 108441"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145506297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between smoking cessation and risk for type 2 diabetes, stratified by post-cessation weight change: A systematic review and meta-analysis 戒烟与2型糖尿病风险之间的关系,通过戒烟后体重变化分层:一项系统综述和荟萃分析。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-10-10 DOI: 10.1016/j.ypmed.2025.108429
Yifan Yu , Yan Li , Thu T. Nguyen , Dahai Yue , Nedelina Tchangalova , Caitlin E. Flouton , Hongjie Liu

Objective

While smoking cessation reduces health risks, its impact on type 2 diabetes mellitus (T2DM) remains complex when considering post-cessation weight gain. This systematic review and meta-analysis examined the association between smoking cessation and diabetes risk stratified by weight change and cessation duration.

Methods

We searched seven databases through April 14, 2025. Observational studies examining smoking cessation, weight changes, and T2DM were included. Random-effects models pooled hazard ratios (HRs) comparing recent and long-term quitters to continuous/never smokers, stratified by weight gain.

Results

Among eleven cohort studies, quitters with weight gain showed increased diabetes risk versus continuous smokers (HR = 1.71, 95 % CI: 1.12, 2.62), with recent quitters having greater risk (HR = 2.20, 95 % CI: 1.27, 3.82) but long-term quitters showing reduced risk (HR = 0.91, 95 % CI: 0.87, 0.95). Quitters without weight gain demonstrated no increased risk (recent: HR = 0.99, 95 % CI: 0.81, 1.02) and lower risk (long-term: HR = 0.84, 95 % CI: 0.81, 0.87). Compared to never-smokers, recent quitters had a higher T2DM risk regardless of weight status (with gain: HR = 1.61, 95 % CI: 1.03, 2.50; without gain: HR = 1.25, 95 % CI: 1.05, 1.48), while long-term quitters showed no significant difference.

Conclusions

Smoking cessation temporarily increases T2DM risk, particularly with weight gain, but becomes protective long-term, emphasizing weight management.
目的:虽然戒烟可以降低健康风险,但考虑到戒烟后体重增加,戒烟对2型糖尿病(T2DM)的影响仍然很复杂。本系统综述和荟萃分析通过体重变化和戒烟持续时间对戒烟和糖尿病风险之间的关系进行了分层。方法:检索截至2025年4月14日的7个数据库。观察性研究包括戒烟、体重变化和2型糖尿病。随机效应模型汇集了危险比(hr),比较了最近和长期戒烟者与连续/从不吸烟者,按体重增加分层。结果:11个队列研究中,戒烟者体重增加显示增加糖尿病风险和连续吸烟者(HR = 1.71,95 % CI: 1.12, 2.62),最近戒烟者有更大的风险(HR = 2.20,95 % CI: 1.27, 3.82),但长期戒烟显示风险降低(HR = 0.91,95 % CI: 0.87, 0.95)。没有体重增加的戒烟者没有增加风险(近期:HR = 0.99,95 % CI: 0.81, 1.02)和更低的风险(长期:HR = 0.84,95 % CI: 0.81, 0.87)。与从不吸烟者相比,无论体重状况如何,最近戒烟者的T2DM风险更高(增加:HR = 1.61,95 % CI: 1.03, 2.50;未增加:HR = 1.25,95 % CI: 1.05, 1.48),而长期戒烟者没有显着差异。结论:戒烟暂时增加2型糖尿病的风险,尤其是体重增加,但长期具有保护作用,强调体重管理。
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引用次数: 0
Tobacco use and eligibility for lung cancer screening among dental patients at an academic institution in Houston, Texas 在德克萨斯州休斯顿的一个学术机构中,牙科患者的烟草使用和肺癌筛查的资格。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-08 DOI: 10.1016/j.ypmed.2025.108438
Ana S. Neumann , Iakovos Toumazis , Jennifer A. O'Brien , Diane Beneventi , Sai Keerthi Annam , Anita Joy-Thomas , Robert J. Volk

Objective

Tobacco use negatively impacts oral and general health and influences dental treatment outcomes. To advance prevention, we surveyed dental patients at an academic institution to characterize their history of tobacco use and eligibility for lung cancer screening (LCS).

Methods

Anonymous surveys were administered to adult dental patients at the UTHealth Houston School of Dentistry between April 2022 and October 2022. Surveys collected information on smoking history, pack-year history, health literacy, personal and family history of lung cancer, and previous LCS. Demographic variables included age, gender, race/ethnicity, and education level.

Results

Among 432 patients (mean age: 46.4, range 18–88 years, 57.0 % female), 22.7 % were patients who currently smoked cigarettes, and 13.2 % were patients who formerly smoked. Smoking rates were highest among males (36.2 %) and patients younger than 50 (26.0 %). Among patients who currently smoked, 44.1 % met eligibility for LCS based on age and a 20+ pack-year smoking history; 43.2 % of patients who formerly smoked were eligible for LCS.

Conclusions

A substantial proportion of patients are eligible for LCS; tailored cessation counseling and electronic-referral pathways could impact screening and cessation support for millions of high-risk adults who visit a dentist each year, closing a critical gap in cancer prevention.
目的:烟草使用对口腔和一般健康产生负面影响,并影响牙科治疗结果。为了促进预防,我们调查了一家学术机构的牙科患者,以描述他们的烟草使用史和肺癌筛查(LCS)的资格。方法:对2022年4月至2022年10月期间UTHealth休斯顿牙科学院的成年牙科患者进行匿名调查。调查收集了吸烟史、包年史、健康素养、个人和家族肺癌史以及既往LCS的信息。人口统计变量包括年龄、性别、种族/民族和教育水平。结果:在432例患者中(平均年龄46.4岁,年龄范围18-88 岁,57.0% %为女性),22.7% %为目前吸烟的患者,13.2% %为以前吸烟的患者。男性(36.2% %)和50岁以下患者(26.0% %)吸烟率最高。在目前吸烟的患者中,44.1% %符合基于年龄和20年以上吸烟史的LCS资格;43.2% 以前吸烟的患者符合LCS的条件。结论:相当大比例的患者符合LCS的条件;量身定制的戒烟咨询和电子转诊途径可能会影响每年数百万去看牙医的高风险成年人的筛查和戒烟支持,从而缩小癌症预防方面的重大差距。
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引用次数: 0
Does loneliness impact intentional weight loss? The role of obesity-related disadvantages and comorbidities 孤独会影响有意减肥吗?肥胖相关的不利因素和合并症的作用。
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-10-11 DOI: 10.1016/j.ypmed.2025.108430
Siniriikka A. Männistö , Anu Joki , Laura-Unnukka Suojanen , Mikko S. Venäläinen , Kirsi H. Pietiläinen , Aila J. Ahola

Objective

Loneliness is increasingly recognized as a significant factor influencing health outcomes, including weight management. Nevertheless, its role in intentional weight loss remains underexplored. The 12-month digital Healthy Weight Coaching (HWC), in Finland, offers a real-world context to investigate this relationship. We explored whether baseline loneliness affects weight loss during HWC and whether comorbidities or perceived obesity-related disadvantages mediate this relationship.

Methods

Data were included from participants enrolled in the HWC between 2016 and 2020. Baseline assessments included loneliness, comorbidities, and perceived obesity-related disadvantages. Weight was self-reported weekly, with body mass index calculated from interpolated weights at three, six, nine, and 12 months. Generalized estimating equations were used to analyze the impact of baseline loneliness on weight change, and ordinary least squares regression analyses were used to analyze mediation.

Results

Participants who felt lonely, somewhat lonely, or not lonely at baseline achieved comparable weight loss. However, higher loneliness was linked to greater perceived obesity-related disadvantages, psychological distress, number of comorbidities, and lower vitality, indirectly leading to lesser weight loss.

Conclusions

Loneliness did not directly hinder weight loss but was linked to health and psychosocial challenges that may indirectly reduce success, highlighting the need for holistic support in weight management.
Trial registration: The trial is registered at clinicaltrials.gov (Clinical Trials Identifier NCT04019249).
目的:孤独越来越被认为是影响健康结果的重要因素,包括体重管理。然而,它在有意减肥中的作用仍未得到充分研究。芬兰为期12个月的数字健康体重指导(HWC)提供了一个真实世界的背景来研究这种关系。我们探讨了基线孤独感是否影响HWC期间的体重减轻,以及合并症或感知到的肥胖相关不利因素是否介导了这种关系。方法:数据来自2016年至2020年期间参加HWC的参与者。基线评估包括孤独感、合并症和感知到的与肥胖相关的不利因素。每周自我报告体重,体重指数在3、6、9和12 个月时根据体重计算。采用广义估计方程分析基线孤独感对体重变化的影响,采用普通最小二乘回归分析分析中介效应。结果:在基线时感到孤独、有些孤独或不孤独的参与者取得了相当的体重减轻。然而,更高的孤独感与更大的肥胖相关的不利因素、心理困扰、合并症的数量和更低的活力有关,间接导致更少的体重减轻。结论:孤独并不直接阻碍减肥,但与健康和社会心理挑战有关,可能间接降低成功,强调在体重管理中需要整体支持。试验注册:该试验在clinicaltrials.gov(临床试验标识符NCT04019249)上注册。
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引用次数: 0
Association between weekend catch-up sleep and white blood cell count among Korean adults: A population-based cross-sectional study 韩国成年人周末补觉与白细胞计数之间的关系:一项基于人群的横断面研究
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-25 DOI: 10.1016/j.ypmed.2025.108474
Juyeon Lee , Ye-Jee Kim , Bo Ram Yang

Objective

This study investigated the association between weekend catch-up sleep (WCS) and systemic inflammation, as indicated by serum white blood cell (WBC) counts.

Methods

A cross-sectional study of 22,143 participants from the Korea National Health and Nutrition Examination Survey (2016–2018, and 2021) categorized into no-WCS (<1 h), moderate WCS (1 to <3 h), and extended WCS (≥3 h). WBC counts were divided into quartiles, and polytomous logistic regression was used to assess associations between WCS and WBC counts. Stratified analyses considered age, sex, body mass index (BMI), sleep duration, and bedtime inconsistency.

Results

Extended WCS was modestly associated with higher WBC counts, particularly in adults aged 20–39 years (odds ratio [OR] = 1.42, 95 % confidence interval [CI]: 1.08, 1.87), 40–64 years (OR = 1.54, 95 % CI: 1.19, 1.99), males (OR = 1.56, 95 %e CI: 1.21, 2.01), individuals with BMI < 25 kg/m2 (OR = 1.45, 95 % CI: 1.21, 1.76), and those with irregular bedtimes (OR = 1.78, 95 % CI: 1.34, 2.37). Moderate WCS was inversely associated with higher BMI (OR = 0.79, 95 % CI: 0.64, 0.97). Significant interactions were observed by age, sex, BMI, and bedtime inconsistency.

Conclusions

Extended WCS was associated with elevated systemic inflammation in specific subgroups. Maintaining regular and moderate sleep patterns may help mitigate low-grade inflammation.
目的研究周末补觉(WCS)与全身炎症之间的关系,并通过血清白细胞(WBC)计数进行分析。方法对来自韩国国家健康与营养调查(2016-2018年和2021年)的22143名参与者进行横断面研究,分为无WCS(1小时)、中度WCS(1至3小时)和延长WCS(≥3小时)。白细胞计数被分成四分位数,并使用多分逻辑回归来评估白细胞计数与白细胞计数之间的关系。分层分析考虑了年龄、性别、身体质量指数(BMI)、睡眠时间和就寝时间不一致。结果WCS延长与白细胞计数升高有一定的相关性,特别是在20-39岁的成年人(优势比[OR] = 1.42, 95%可信区间[CI]: 1.08, 1.87)、40-64岁的成年人(OR = 1.54, 95% CI: 1.19, 1.99)、男性(OR = 1.56, 95% CI: 1.21, 2.01)、BMI = 25 kg/m2的个体(OR = 1.45, 95% CI: 1.21, 1.76)和就寝时间不规律的个体(OR = 1.78, 95% CI: 1.34, 2.37)。中度WCS与较高的BMI呈负相关(OR = 0.79, 95% CI: 0.64, 0.97)。年龄、性别、BMI和就寝时间不一致观察到显著的相互作用。结论在特定亚组中,WCS延长与全身炎症升高相关。保持规律和适度的睡眠模式可能有助于减轻轻度炎症。
{"title":"Association between weekend catch-up sleep and white blood cell count among Korean adults: A population-based cross-sectional study","authors":"Juyeon Lee ,&nbsp;Ye-Jee Kim ,&nbsp;Bo Ram Yang","doi":"10.1016/j.ypmed.2025.108474","DOIUrl":"10.1016/j.ypmed.2025.108474","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated the association between weekend catch-up sleep (WCS) and systemic inflammation, as indicated by serum white blood cell (WBC) counts.</div></div><div><h3>Methods</h3><div>A cross-sectional study of 22,143 participants from the Korea National Health and Nutrition Examination Survey (2016–2018, and 2021) categorized into no-WCS (&lt;1 h), moderate WCS (1 to &lt;3 h), and extended WCS (≥3 h). WBC counts were divided into quartiles, and polytomous logistic regression was used to assess associations between WCS and WBC counts. Stratified analyses considered age, sex, body mass index (BMI), sleep duration, and bedtime inconsistency.</div></div><div><h3>Results</h3><div>Extended WCS was modestly associated with higher WBC counts, particularly in adults aged 20–39 years (odds ratio [OR] = 1.42, 95 % confidence interval [CI]: 1.08, 1.87), 40–64 years (OR = 1.54, 95 % CI: 1.19, 1.99), males (OR = 1.56, 95 %e CI: 1.21, 2.01), individuals with BMI &lt; 25 kg/m<sup>2</sup> (OR = 1.45, 95 % CI: 1.21, 1.76), and those with irregular bedtimes (OR = 1.78, 95 % CI: 1.34, 2.37). Moderate WCS was inversely associated with higher BMI (OR = 0.79, 95 % CI: 0.64, 0.97). Significant interactions were observed by age, sex, BMI, and bedtime inconsistency.</div></div><div><h3>Conclusions</h3><div>Extended WCS was associated with elevated systemic inflammation in specific subgroups. Maintaining regular and moderate sleep patterns may help mitigate low-grade inflammation.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"202 ","pages":"Article 108474"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145620083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental health emergencies and mortality following public fine particulate matter alerts: A Nationwide case-crossover study in South Korea 公共细颗粒物警报后的精神卫生突发事件和死亡率:韩国全国病例交叉研究
IF 3.2 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-14 DOI: 10.1016/j.ypmed.2025.108467
Hoyol Jhang , Whanhee Lee , Jong Tae Lee , Yoonhee Kim , Chul-Hyun Cho , Soojung Kim , Seung-Ah Choe

Objective

Little is known about whether issuing particulate matter ≤2.5 μm (PM2.5) alerts influences emergency department presentations for mental health or mortality. We evaluated the impact of PM2.5 alerts on mental disorder-related emergency visit and mortality.

Methods

We conducted a time-stratified case-crossover analysis comparing PM2.5 alert versus non-alert days between 1 January 2015 and 31 December 2021 using multiple South Korean databases. Alert days were 1:1 matched to non-alert days on the basis of daily mean municipal-level of PM2.5. We applied conditional Poisson regression models, stratified by region, to estimate relative risks of mental disorder, related emergency department visits and mortality for PM2.5 alert.

Results

A 20 μg/m3 increase in PM2.5 was associated with elevated risks of mental disorder-related emergency department visits and mortality. On PM2.5 alert days, the risk of mental disorder-related emergency visits was lower compared with matched non-alert days (RR = 0.94, 95 % confidence intervals [CI]: 0.92, 0.97). This association was observed for both organic and non-organic mental disorders. All-cause, cardiovascular, and respiratory mortality showed small, non-significant increases on alert days.

Conclusions

Issuance of PM2.5 alerts in South Korea was associated with a modest reduction in emergency visits for mental disorders but did not correspond with lower mortality.
目的:发布≤2.5 μm (PM2.5)的颗粒物警报是否会影响急诊室的心理健康报告或死亡率,目前尚不清楚。我们评估了PM2.5警报对精神障碍相关急诊就诊和死亡率的影响。方法:我们使用多个韩国数据库,对2015年1月1日至2021年12月31日PM2.5警报日与非警报日进行了时间分层病例交叉分析。以全市PM2.5日均值为基础,预警日与非预警日的匹配比例为1:1。我们应用按地区分层的条件泊松回归模型来估计PM2.5警报时精神障碍、相关急诊就诊和死亡率的相对风险。结果:PM2.5每增加20 μg/m3,与精神障碍相关的急诊就诊和死亡风险升高相关。在PM2.5警戒日,与非警戒日相比,精神障碍相关急诊就诊的风险较低(RR = 0.94,95 %可信区间[CI]: 0.92, 0.97)。器质性和非器质性精神障碍均观察到这种关联。在警戒日,全因死亡率、心血管死亡率和呼吸系统死亡率均有小幅、不显著的增加。结论:在韩国,PM2.5警报的发布与精神障碍急诊人数的适度减少有关,但与较低的死亡率无关。
{"title":"Mental health emergencies and mortality following public fine particulate matter alerts: A Nationwide case-crossover study in South Korea","authors":"Hoyol Jhang ,&nbsp;Whanhee Lee ,&nbsp;Jong Tae Lee ,&nbsp;Yoonhee Kim ,&nbsp;Chul-Hyun Cho ,&nbsp;Soojung Kim ,&nbsp;Seung-Ah Choe","doi":"10.1016/j.ypmed.2025.108467","DOIUrl":"10.1016/j.ypmed.2025.108467","url":null,"abstract":"<div><h3>Objective</h3><div>Little is known about whether issuing particulate matter ≤2.5 μm (PM<sub>2.5</sub>) alerts influences emergency department presentations for mental health or mortality. We evaluated the impact of PM<sub>2.5</sub> alerts on mental disorder-related emergency visit and mortality.</div></div><div><h3>Methods</h3><div>We conducted a time-stratified case-crossover analysis comparing PM<sub>2.5</sub> alert versus non-alert days between 1 January 2015 and 31 December 2021 using multiple South Korean databases. Alert days were 1:1 matched to non-alert days on the basis of daily mean municipal-level of PM<sub>2.5</sub>. We applied conditional Poisson regression models, stratified by region, to estimate relative risks of mental disorder, related emergency department visits and mortality for PM<sub>2.5</sub> alert.</div></div><div><h3>Results</h3><div>A 20 μg/m<sup>3</sup> increase in PM<sub>2.5</sub> was associated with elevated risks of mental disorder-related emergency department visits and mortality. On PM<sub>2.5</sub> alert days, the risk of mental disorder-related emergency visits was lower compared with matched non-alert days (RR = 0.94, 95 % confidence intervals [CI]: 0.92, 0.97). This association was observed for both organic and non-organic mental disorders. All-cause, cardiovascular, and respiratory mortality showed small, non-significant increases on alert days.</div></div><div><h3>Conclusions</h3><div>Issuance of PM<sub>2.5</sub> alerts in South Korea was associated with a modest reduction in emergency visits for mental disorders but did not correspond with lower mortality.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"202 ","pages":"Article 108467"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Preventive medicine
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