Radiation Physics and Chemistry最新文献

{"title":"Effects of gamma and electron-beam irradiations on the stability of free radicals, bioactive compounds and microbial characteristics of turmeric powder","authors":"Zeinab Aghamohseni ,&nbsp;Saeideh Esmaeili ,&nbsp;Samira Berenji Ardestani ,&nbsp;Mohammad Esmaeil Akbari ,&nbsp;Amir Moslehi ,&nbsp;Elham Khanniri ,&nbsp;Marzieh Ahmadi-Roshan ,&nbsp;Amirali Anvar","doi":"10.1016/j.radphyschem.2024.112368","DOIUrl":"10.1016/j.radphyschem.2024.112368","url":null,"abstract":"<div><div>Turmeric is a functional ingredient commonly used in food, pharmaceutical, and cosmetic products due to its health benefits and bioactivity, including anti-inflammatory, antioxidant, and anticancer benefits. Irradiation is a common technique used to decontaminate microorganisms and extend the shelf life of spices. However, there are scientific debates over the use of irradiation in food products. This study aimed to assess the effects of ionizing radiation, including gamma rays and electron beams, on bioactive compounds and microbial characteristics of turmeric powder. Technically, high-performance liquid chromatography with UV–Vis detection was used to assess bioactive compounds. Another aim of the present study was to determine free radicals in irradiated and non-irradiated samples within one month of storage using electron paramagnetic resonance (EPR). Results showed that gamma and electron-beam irradiations could decrease microbial contamination of turmeric by approximately 5 and 6 log cfu/g, respectively. Contents of bioactive compounds increased in irradiated samples and curcumin contents in gamma and electron-beam irradiated samples were 232–248 and 215–266 mg/g dry weight (dw), respectively. Furthermore, the study detected that free radicals increased in all irradiated samples immediately after irradiation but decreased over time. Decrease in EPR signals was faster in gamma-irradiated samples during storage. Numbers of free radicals induced by gamma and electron-beam irradiations were 6.59–4.70, 2.69–1.60, 1.61–1.34, and 0.99–1.05 on days 0, 7, 14, and 21, respectively. After 21 days of storage, the numbers of free radicals in all non-irradiated and irradiated samples were similar. Therefore, free radicals induced by irradiations were degraded during storage and eliminated after 21 days.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112368"},"PeriodicalIF":2.8,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive analysis of gamma irradiation-induced crystallographic transformations in TiC nanoparticles using X-ray diffraction techniques","authors":"Raisa R. Hakhiyeva ,&nbsp;Afsun S. Abiyev ,&nbsp;Elchin M. Huseynov","doi":"10.1016/j.radphyschem.2024.112363","DOIUrl":"10.1016/j.radphyschem.2024.112363","url":null,"abstract":"<div><div>Alterations in the structural composition of titanium carbide (TiC) nanocrystals induced by gamma radiation exposure were systematically investigated. A sample with an average grain size of approximately from 40 nm to 60 nm and possessing a cubic crystal structure (Fm3 <span><math><mrow><mover><mi>m</mi><mo>‾</mo></mover></mrow></math></span>) was selected for the experiment. The X-ray diffraction method has been employed to analyze the changes that occurred after gamma radiation. The experimental results were theoretically analyzed employing the Rietveld, Scherrer, and Williamson-Hall methods, with subsequent comparisons conducted among them. Furthermore, the degree of amorphization induced by gamma radiation throughout the structure was quantified.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112363"},"PeriodicalIF":2.8,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A closer look to dose assessment and radiation shielding characteristics of concrete doped magnetite irradiated with 252Cf mixed radiation radionuclide: A Watt Fission approach and Doppler effect","authors":"Roya Boudaghi Malidarreh ,&nbsp;N. Almousa ,&nbsp;Iskender Akkurt ,&nbsp;Shams A.M. Issa ,&nbsp;Hesham M.H. Zakaly","doi":"10.1016/j.radphyschem.2024.112364","DOIUrl":"10.1016/j.radphyschem.2024.112364","url":null,"abstract":"<div><div>Nuclear radiation emitted by fusion reactors, nuclear power plants, and medical establishments presents potential risks to living organisms personnel, necessitating the implementation of protective measures. To enhance radiation protection for patients workers, various materials can be utilized. Concrete, augmented with various additives, has historically acted as a shielding material. Hence, recent research has predominantly focused on enhancing concrete's ability to attenuate the harmful energy emitted by nuclear sources through modifications to its composition. Accordingly, in the present work, the dose evaluation and radiation shielding characteristics of a range of concrete magnetite (CM) formulations designated as CM-0 (control sample), CM-25, CM-50, CM-75, and CM-100 have been analyzed using MCNPX Monte Carlo (MC) approach and theoretical computations concerning ²⁵²Cf mixed radiation radionuclide. In this work, the Watt Fission distribution was employed to derive the neutron spectrum of CM samples, and findings have been thoroughly elucidated in the presence and absence of the specified samples. Then, utilizing the Doppler Effect, the gamma photon spectrum within shielding materials exposed to a spontaneous fission ²⁵²Cf source is extracted and characterized. Estimation of Half Value Thickness (HVT) and Mean Free Path (MFP) are provided across a broad spectrum of energy levels. The analysis confirms the successful development of a new type of concrete magnetite (CM) sample that exhibits lower radiation exposure compared to the control sample. This study offers valuable insights into the use of concrete in shielding against mixed radiation radionuclides and opens the door for future research involving similar materials. Specifically, the CM-100 sample demonstrated the lowest half-value thickness (HVT) and provided the most effective reduction of both neutron and gamma radiation. The findings suggest that increasing the concentration of magnetite in concrete greatly enhances its ability to shield against mixed neutron-gamma radiation. This innovation has promising potential for applications in radiation protection, particularly within nuclear reactors and medical facilities. The CM-100 sample showed a notable improvement, achieving an HVT of 0.012 cm and a dose rate reduction of 2.95 × 10⁻⁹ Sv.h⁻¹, in contrast to the control sample (CM-0), which had an HVT of 10.358 cm and an equivalent dose rate of 2.84 × 10⁻⁹ Sv.h⁻¹. These results underscore the superior shielding properties of the magnetite-doped concrete formulations.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112364"},"PeriodicalIF":2.8,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excitation functions for Sc radioisotopes production via (α,x) nuclear reactions on natural calcium up to 25 MeV","authors":"Lutfi A. Hasnowo ,&nbsp;Alexander A. Garapatski ,&nbsp;Nelson E. Villa ,&nbsp;Maria S. Larkina ,&nbsp;Ivan V. Lomov ,&nbsp;Mekhman S. Yusubov","doi":"10.1016/j.radphyschem.2024.112361","DOIUrl":"10.1016/j.radphyschem.2024.112361","url":null,"abstract":"<div><div>Scandium (Sc) radioisotopes have been attracting increasing attention in medical applications. ⁴⁷Sc, which has the potential for targeted radiotherapy, is quite promising as a candidate for theranostic pairing with the β⁺-emitting radioisotope ⁴³Sc or ^44gSc. The excitation functions for producing ^{43,44m,44g,46,47}Sc through (α,x) reactions on natural calcium (Ca) up to an energy of 25 MeV were experimentally measured and critically compared with previous experimental reports and theoretical data obtained by EMPIRE-3.2.3 code and from TENDL-2021 library. The physical yields for producing of ^{43,44m,44g,46,47}Sc through (α,x) reactions on ^natCa were determined using the measured production cross-section of the radionuclides and the stopping powers.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112361"},"PeriodicalIF":2.8,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of a gel dosimeter based on Ag nanoparticles for applications in radiation therapy with synchrotron X-rays at ultrahigh dose rate compared to 60Co γ-rays","authors":"Yasser S. Soliman ,&nbsp;Marie Capron ,&nbsp;Diego Pontoni ,&nbsp;Michael Krisch ,&nbsp;Paolo Pellicioli","doi":"10.1016/j.radphyschem.2024.112351","DOIUrl":"10.1016/j.radphyschem.2024.112351","url":null,"abstract":"<div><div>A silver nitrate (AgNO₃) gel was developed and evaluated as a dosimeter for synchrotron X-ray-based studies in microbeam radiation therapy (MRT) and FLASH radiation therapy. The gel was irradiated at the European Synchrotron Radiation Facility (ID17 Biomedical beamline) with a continuous X-ray spectrum in the 50–600 keV range and a dose rate of 11.6 kGy/s. The spectrophotometric response after irradiation at this beamline was compared with the response at a conventional ⁶⁰Co γ-ray source providing a dose rate of 0.27 Gy/s. Ag ⁺ ions in the gel dosimeter undergo reduction to Ag^o nanoparticles, as detected at 450 nm, which is a surface plasmon resonance band. The intensity of this band increased linearly with increasing absorbed dose up to 100 Gy, and improved with the addition of glycerol. The gel dosimeter exhibited the lowest detectable dose (LDD) of 75.9% lower and a dose deposition of 76% higher for ID17 beamline irradiation than for ⁶⁰Co irradiation. The theoretical relative response H_Q,Qo for the gel irradiated at the synchrotron was 1.70, which is in close agreement with the experimental relative response F_Q,Qo = 1.76. These results confirm the dose enhancement in the gel irradiated with orthovoltage X-rays. The good properties of the silver nitrate gel, together with its increased sensitivity to orthovoltage X-ray irradiation and modest overall uncertainty of 5.8% (2σ), confirm that the gel is a valid dosimeter for measurements at ultrahigh dose rates for synchrotron radiotherapy. The dosimeter is also a promising candidate for dose enhancement factor measurements in nanoparticle-based radiotherapy techniques.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112351"},"PeriodicalIF":2.8,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of radiation dose and cancer risk for paediatric digital radiography in a Moroccan hospital","authors":"Noureddine Elamri,&nbsp;Mustapha bougteb,&nbsp;Maroine Tahiri,&nbsp;Redouane El Baydaoui,&nbsp;Mounir Mkimel","doi":"10.1016/j.radphyschem.2024.112352","DOIUrl":"10.1016/j.radphyschem.2024.112352","url":null,"abstract":"<div><div>Pediatric radiography is the first line of most diagnostic examinations and an effective tool that provides important information about the patient's health status.</div><div>This study aims to investigate the Entrance Surface Dose (ESD) and organ doses for pediatric patients undergoing imaging procedures of the abdomen, chest, pelvis, and nasopharynx using Optically Stimulated Luminescence Dosimeters OSLDs and an anthropomorphic phantom.</div><div>An ATOM pediatric 5-year-old phantom was imaged using a Digital Radiography (DR) based on similar conditions of routine radiography (exposure parameters kVp, mAs, SID: Source Image receptor Distance). The OSLDs were inserted at the appropriate sites to measure localized doses in the sensitive organs.</div><div>The results showed that the entrance surface doses for the pediatric patients were 0.17 ± 0.03 mGy, 0.10 ± 0.00 mGy, 0.46 ± 0.00 mGy, and 0.42 ± 0.02 mGy, respectively, for the abdomen (AP), chest (AP), pelvis (AP), and nasopharynx (LAT). The range of organ doses were 0.05–0.45 mGy, 0.01–0.44 mGy, 0.13–1.05 mGy, and 0.084–0.99 mGy for the abdomen, chest, pelvis, and nasopharynx examination, respectively. Effective doses (ED) were 0.088 ± 0.021 mSv, 0.011 ± 0.004 mSv, 0.058 ± 0.007 mSv, and 0.044 ± 0.024 mSv for the abdomen, chest, pelvis, and nasopharynx examination, respectively.</div><div>The likelihood of cancer, as determined by the ICRP health risk model with a rate of 500 cases per 10 000 person-Sv (5% per sievert), estimated that a 0.015 case of health risk (0.3 person-Sv × 5% per sievert) may in the future be attributable to four X-ray pediatric procedures conducted in 2022.</div><div>The ESD, ED, and organ dose values are deemed acceptable compared to those reported in the literature. Although the risk of incidence and mortality from cancer during life is minimal, it should not be ignored.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112352"},"PeriodicalIF":2.8,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial results of hard X-ray spectroscopy by LaBr3(Ce) detector for runaway electron study in Thailand Tokamak-1","authors":"Kitti Rongpuit ,&nbsp;Apiwat Wisitsorasak ,&nbsp;Siriyaporn Sangaroon ,&nbsp;Kunihiro Ogawa ,&nbsp;Nakarin Pattanaboonmee ,&nbsp;Weerapong Chewpraditkul ,&nbsp;Suwat Tangwancharoen ,&nbsp;Suebsak Suksaengpanomrung ,&nbsp;Arlee Tamman ,&nbsp;Boonyarit Chatthong ,&nbsp;Nopporn Poolyarat ,&nbsp;Mitsutaka Isobe","doi":"10.1016/j.radphyschem.2024.112346","DOIUrl":"10.1016/j.radphyschem.2024.112346","url":null,"abstract":"<div><div>Thailand Tokamak-1 (TT-1) successfully achieved its first plasma operation in early 2023. Understanding the behavior of high-energy runaway electrons (RE) during plasma discharges is crucial in TT-1 due to the potential risk of significant damage to in-vessel components. To study the RE behavior and analyze its characteristics, the LaBr<span><math><msub><mrow></mrow><mrow><mn>3</mn></mrow></msub></math></span>(Ce) detector was employed for measuring hard X-ray emissions in TT-1. In this study, we first characterized the LaBr<span><math><msub><mrow></mrow><mrow><mn>3</mn></mrow></msub></math></span>(Ce) detector in the laboratory and then performed hard X-ray spectroscopy in TT-1. Calibration sources, including ¹³³Ba, ¹³⁷Cs, ²²Na, and ⁶⁰Co, with energies up to 1.33 MeV, were used in the laboratory. The detector was calibrated using biased high voltage of -1000 V. It was found to have an energy resolution of approximately 6.2% at an energy of 0.662 MeV. After calibration, the detector was installed at TT-1 to measure hard X-ray. We analyze the hard X-ray emission from discharge #2183 during a selected time interval. It is found that the high-energy hard X-ray emissions reach up to approximately 500 keV. Assuming a simple Maxwellian distribution of the RE population, their temperature is estimated to be <span><math><mrow><mn>224</mn><mo>±</mo><mn>5</mn></mrow></math></span> keV. These findings confirm the presence of high-energy runaway electrons during TT-1’s plasma discharges. However, to accurately derive the runaway electron energy spectrum from the hard X-ray energy spectrum, the unfolding technique is required. In future work, we plan to apply the unfolding method, conduct numerical simulations on the physics of runaway electrons, and employ Monte Carlo simulations on the hard X-ray emissions.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112346"},"PeriodicalIF":2.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monte Carlo source verification of Elekta Synergy for pMLC collimated electron beams","authors":"D. van Eeden, F.C.P. du Plessis","doi":"10.1016/j.radphyschem.2024.112359","DOIUrl":"https://doi.org/10.1016/j.radphyschem.2024.112359","url":null,"abstract":"In previous works, an electron beam source was developed that models its energy spectrum with a Lévy distribution. This source is used in BEAMnrc Monte Carlo simulation. It was benchmarked against water tank measurements for electrons delivered through an applicator collimation system, and it was found to agree with 2%/2 mm. This study uses this electron source further by investigating its ability to simulate electrons collimated by the photon multi-leaf collimators for MERT applications. Simulated and Gafchromic EBT3 depth dose and profile data were compared.","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"76 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis and thermoluminescent response of ZnO particles using Mimosa tenuiflora bark extract","authors":"Milena Lima Guimarães, Ricardo Ferrari Ferraz, Raquel Aline Pessoa Oliveira, Helinando Pequeno de Oliveira","doi":"10.1016/j.radphyschem.2024.112350","DOIUrl":"https://doi.org/10.1016/j.radphyschem.2024.112350","url":null,"abstract":"The continuous growth of industrial activity has led to environmental degradation, highlighting the need for alternative and environmentally friendly chemical methods for creating technological solutions for society. Green synthesis offers a promising approach for the large-scale production of materials for several applications. Herein, the synthesis of zinc oxide (ZnO) particles is proposed by a green route using <ce:italic>Mimosa tenuiflora</ce:italic> bark extract for evaluation of the thermoluminescent (TL) response of the produced material at different calcination temperatures (400 °C, 700 °C, and 1000 °C). The resulting material was evaluated from X-ray diffraction (XRD), scanning electron microscope (SEM), X-ray fluorescence (XRF), UV–visible (UV–vis) spectroscopy, and thermoluminescence (TL) measurements. The ZnO powder exhibited a single-phase wurtzite ZnO with a hexagonal unit cell crystal system with the crystallite size affected by the calcination temperature. ZnO/Teflon® pellets were prepared to assess the TL response under irradiation with a<ce:sup loc=\"post\">90</ce:sup>Sr beta radiation source between 10 Gy and 300 Gy. The samples calcined at 400 and 700 °C did not show a TL response, while the samples calcined at 1000 °C exhibited an intense TL signal, with a prominent peak at 308 °C and a linear growth in the range of 10–300 Gy, reinforcing the perspectives for use of ZnO-1000/Teflon® pellets in TL dosimetry.","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"140 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dosimetric and radiobiological comparison of TomoTherapy and IMRT plans for prostate cancer","authors":"Amin Pourfarshid, Asghar Mesbahi, Mohammad Mohammadzadeh, Mikaeil Molazadeh, Ahad Zeinali","doi":"10.1016/j.radphyschem.2024.112356","DOIUrl":"https://doi.org/10.1016/j.radphyschem.2024.112356","url":null,"abstract":"The purpose of this study was to investigate the dosimetric and radiobiological parameters of IMRT and TomoTherapy techniques to determine the best technique for the treatment of prostate cancer. Dynamic IMRT and Helical TomoTherapy (HT) radiotherapy techniques were used for the treatment planning of 10 patients with prostate cancer. Tumor Control Probability (TCP) and Normal Tissue Complication Probability (NTCP) based on Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) models as radiobiological parameters in addition to the multiple dosimetrics including Equivalent Uniform Dose (EUD), Heterogeneity Index (HI), and Conformity Index (CI) were evaluated. The mean NTCP value based on the LKB model for the IMRT method was higher than that for the HT method by approximately 4.62% for the bladder and 4.89% for the rectum, respectively. Similarly, in the RS model, the average NTCP values for IMRT were approximately 4.14% and 12.78% for the bladder and rectum, higher than the HT. The mean values of the HI and CI indices in IMRT were obtained as 0.06 ± 0.01 and 1.13 ± 0.08, respectively. With the HT technique, the index values were equal to 0.04 ± 0.01 and 1.09 ± 0.05, respectively. The mean doses to the rectum and right/left femoral heads were 13.19%, 11.32%, and 10.90% higher in IMRT than in HT, respectively. However, the mean dose to the bladder tissue was 17.13% higher in HT than in IMRT. Our study demonstrated that HT plans were superior to IMRT plans in terms of estimated NTCP using radiobiological models (LKB and RS) for healthily tissues. Except for the higher treatment duration, while having a desired and uniform dose distribution to the tumor, the TomoTherapy technique leads to preservation of healthy organs.","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"225 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}