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What do the GWAS Studies Say About Language in Schizophrenia. GWAS研究如何解释精神分裂症患者的语言?
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-09-23 DOI: 10.12740/PP/OnlineFirst/208424
Przemysław Zakowicz, Bartłomiej Sporniak, Maksymilian Grabarczyk, Maria Skibińska, Joanna Pawlak

Introduction: Schizophrenia links with altered language structure and may be evolutionary consequence of language development. High heritability of the disease led to recent endeavour in explaining the genetic background. Genome-Wide Association Studies (GWAS) indicate schizophrenia as highly polygenic disease with many receptor and synaptic plasticity pathways engaged.

Material and methods: Here we present a systematic review on the topic of schizophrenia GWAS findings and its potential relevance to language skills. We used GWAS catalog data to identify all significant associations in schizophrenia (including selected endophenotypes) and studied its relevance in the context of published data on language phenotypes associations.

Results: Among genes involved in language evolution, FOXP1 and ROBO2 were indicated by GWAS as associated with schizophrenia. Evidence on schizophrenia linked SNPs was found for association with intelligence, educational attainment, cognitive abilities and language processing brain structures imaging results.

Conclusions: The review discusses hypotheses of language alterations in schizophrenia as a consequence of impaired synaptic plasticity and neural network formation.

精神分裂症与语言结构改变有关,可能是语言发展的进化结果。这种疾病的高遗传性促使人们最近努力解释其遗传背景。全基因组关联研究(GWAS)表明,精神分裂症是一种高度多基因疾病,涉及许多受体和突触可塑性途径。材料和方法:在这里,我们对精神分裂症GWAS的研究结果及其与语言技能的潜在相关性进行了系统的综述。我们使用GWAS目录数据来确定精神分裂症的所有重要关联(包括选定的内表型),并在已发表的语言表型关联数据的背景下研究其相关性。结果:在参与语言进化的基因中,GWAS提示FOXP1和ROBO2与精神分裂症相关。有证据表明,与精神分裂症相关的snp与智力、受教育程度、认知能力和语言处理大脑结构成像结果有关。结论:本文讨论了精神分裂症中语言改变是突触可塑性和神经网络形成受损的结果的假设。
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引用次数: 0
Psychiatric disorders among adolescents residing at Youth Educational Centers in Silesia in Poland. 居住在波兰西里西亚青年教育中心的青少年的精神疾病。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-09-10 DOI: 10.12740/PP/OnlineFirst/207301
Karolina Zofia Kamińska, Michał Ciołek, Izabela Rosół, Magdalena Matlakiewicz, Maria Potaczek, Lena Cichoń, Krzysztof Maria Wilczyński, Małgorzata Janas-Kozik

Objectives: In Polish Youth Educational Centres underage individuals exhibiting signs of delinquency are accommodated. A significant concern is the presence of mental health disorders among these institutions' residents, which may influence their rehabilitation process. The aim of this study was to evaluate the prevalence of mental health disorders among residents of Youth Educational Centres in the Silesian Voivodeship.

Methods: The study was conducted between February and November 2022 in two Youth Educational Centres located in the Silesian Voivodeship. 80 individuals participated in the study (60% boys, 40% girls). Participation was voluntary and anonymous. A semi-structured psychiatric interview K-SADS-PL was employed, incorporating questionnaires covering mania, depression, conduct disorders, and substance use disorders.

Results: Among the study participants, 12.5% (n = 10) had been diagnosed with mental disorders prior to the start of the study. Criteria for Major Depressive Disorder were met by 26.25% of participants, including 20.8% of boys and 34.37% of girls, with irritability reported in 19 of the 21 individuals diagnosed with depression. Conduct disorders were observed in 52.5% of participants. Furthermore, 39% of respondents consumed alcohol at least three times per week, and 70% used cannabis at least once a week.

Conclusions: Research on the mental health of adolescents in Youth Educational Centres in Poland highlights a high prevalence of depressive disorders and problematic patterns of psychoactive substance use among residents, which may negatively impact their functioning and prognosis. Interventions are essential to facilitate beneficial behavioural changes in these minors and to counteract their demoralisation.

目标:在波兰青年教育中心,有犯罪迹象的未成年人被安置。令人严重关切的是,这些机构的住客中存在精神健康障碍,这可能影响他们的康复过程。这项研究的目的是评估西里西亚省青年教育中心居民中精神健康障碍的患病率。方法:研究于2022年2月至11月在西里西亚省的两个青年教育中心进行,共有80人参加了研究(60%为男孩,40%为女孩)。参与是自愿和匿名的。采用半结构化精神病学访谈K-SADS-PL,包括躁狂、抑郁、行为障碍和物质使用障碍问卷。结果:在研究参与者中,12.5% (n = 10)在研究开始前被诊断患有精神障碍。26.25%的参与者符合重度抑郁症的标准,其中包括20.8%的男孩和34.37%的女孩,21名被诊断为抑郁症的人中有19人易怒。52.5%的参与者存在行为障碍。此外,39%的答复者每周至少饮酒三次,70%的人每周至少吸食一次大麻。结论:关于波兰青年教育中心青少年心理健康的研究突出表明,居民中抑郁症和精神活性物质使用问题模式的患病率很高,这可能对他们的功能和预后产生负面影响。干预措施对于促进这些未成年人有益的行为改变和消除他们的士气低落至关重要。
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引用次数: 0
MoodMon - the first Polish application using AI in bipolar disorder and recurrent depressive disorders. patients preliminary assessment. MoodMon -波兰第一个使用AI治疗双相情感障碍和复发性抑郁症的应用程序。患者初步评估。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-09-07 DOI: 10.12740/PP/OnlineFirst/207280
Marlena Sokół-Szawłowska, Małgorzata Sochacka

Objectives: The analysis aims to present the subjective assessment of the MoodMon mobile application by users diagnosed with BD and MDD.

Methods: Data were obtained from 95 participants based on a 12-question survey. It was a part of a large clinical study of the MoodMon system.

Results: The reception of the MoodMon application was very similar regardless of the diagnosis. For most respondents, the application was a neutral tool (BD - 50.7%; MDD - 43.5%). Subjective satisfaction with using the application was reported by most users. The application was beneficial for 56.9% of respondents with BD and 78.3% with MDD disorders, primarily due to the ability to use modern technology to control symptoms. Most respondents did not see the need for changes to the application (BD - 70.8%; MDD - 60.9%). However, a small group suggested modifications to the form of voice sampling and the variety of questions. Nearly half of the patients with BD (48.6%) expressed a willingness to use the MoodMon application in the future, and a significantly higher percentage (73.9%) of those with MDD indicated the same.

Conclusions: In the subjective opinion of users, the MoodMon application is perceived as safe, useful and helpful in the treatment of affective disorders.

目的:本分析旨在呈现诊断为BD和MDD的用户对MoodMon移动应用程序的主观评价。方法:对95名参与者进行问卷调查,共12个问题。这是MoodMon系统大型临床研究的一部分。结果:无论诊断如何,MoodMon应用程序的接受情况非常相似。对于大多数受访者来说,应用程序是一个中立的工具(BD - 50.7%; MDD - 43.5%)。大多数用户报告了使用该应用程序的主观满意度。该应用对56.9%的双相障碍患者和78.3%的重度抑郁症患者有益,主要是由于能够使用现代技术来控制症状。大多数受访者认为不需要对应用程序进行更改(BD - 70.8%; MDD - 60.9%)。然而,一小群人建议修改声音采样的形式和问题的种类。近一半的双相障碍患者(48.6%)表示愿意在未来使用MoodMon应用程序,而重度抑郁症患者的比例(73.9%)明显更高。结论:在用户的主观意见中,MoodMon应用程序被认为是安全的,有用的,有助于治疗情感障碍。
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引用次数: 0
MoodMon application for patients with affective disorders created in Poland - results of the study of the system's effectiveness based on artificial intelligence algorithms. 在波兰创建的情感障碍患者的MoodMon应用程序-基于人工智能算法的系统有效性研究结果。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-09-07 DOI: 10.12740/PP/OnlineFirst/196927
Marlena Sokół-Szawłowska, Małgorzata Sochacka

Objectives: In a group of patients diagnosed with BD and MDD, an analysis was conducted to evaluate the efficacy of AI algorithms in detecting mental state changes based on physical voice parameters.

Methods: The MoodMon system was developed, including a mobile application for smartphones. In the first stage, the AI was trained using objective data and clinical assessments conducted by psychiatrists, which included 17-item versions of the HDRS (Hamilton Depression Rating Scale) and YMRS (Young Mania Rating Scale) scales, and the CGI (Clinical Global Impression) scale. The second stage was to further refine the AI using individual and population data and generate alerts when subtle changes in mental state were detected. Both stages of the study lasted a total of 944 days.

Results: Physical voice parameters can serve as biomarkers in affective disorders. The most effective in detecting changes in mental state were 19 specific physical voice parameters. The system showed high performance, with the following sensitivity (true positive rate - TPR) and specificity (true negative rate - TNR) values - for both diagnoses: TPR = 89.5%, TNR = 98.8%; BD: TPR = 89.6%, TNR = 98.9%; MDD: TPR = 89.1%, TNR = 98.5%. MoodMon helped to accurately monitor and predict changes in the mental state of patients with affective disorders.

Conclusions: The MoodMon system is an objective AI tool that effectively identifies the initial period of mental state changes in affective disorders based on physical voice parameters.

目的:在一组诊断为BD和MDD的患者中,分析评估AI算法基于身体语音参数检测精神状态变化的有效性。方法:开发MoodMon系统,包括智能手机移动应用程序。在第一阶段,人工智能使用客观数据和精神病学家进行的临床评估进行训练,其中包括17项版本的HDRS(汉密尔顿抑郁评定量表)和YMRS(青年躁狂评定量表)量表,以及CGI(临床总体印象)量表。第二阶段是利用个人和群体数据进一步完善人工智能,并在检测到精神状态的细微变化时发出警报。两个阶段的研究总共持续了944天。结果:生理语音参数可作为情感性障碍的生物标志物。在检测精神状态变化方面最有效的是19个特定的生理声音参数。该系统表现出高性能,对两种诊断的敏感性(真阳性率- TPR)和特异性(真阴性率- TNR)值如下:TPR = 89.5%, TNR = 98.8%;Bd: TPR = 89.6%, TNR = 98.9%;Mdd: TPR = 89.1%, TNR = 98.5%。MoodMon有助于准确监测和预测情感性障碍患者精神状态的变化。结论:MoodMon系统是一种客观的人工智能工具,可以根据身体语音参数有效识别情感性障碍患者初始阶段的精神状态变化。
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引用次数: 0
"You have to let go." The experience of aging among non-heterosexual women aged 50 and over. “你必须放手。”50岁及以上非异性恋女性的衰老经历。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-08-31 DOI: 10.12740/PP/192116
Olga Edyta Żukowicz

Objectives: The aim of the study is to present the body image of women aged 50+ living in Poland with a declared non-heterosexual orientation in the context of aging, menopause, sexual and gender identity.

Methods: In-depth, semi-structured interviews with non-heterosexual ciswomen aged 50-67, focused around three main areas: menopause, body image and aging.

Results: Thematic analysis allowed for the identification of two main thematic areas: (1) menopause as re-integration with the body, (2) breaking away from heteronormative femininity. Additionally, in the second theme, a subcategory was identified: negotiating gender identity - nonbinary lesbianism.

Conclusions: The analysis of narratives indicates a preservation of a positive body image amidst a great diversity in experiencing aging and menopause among non-heterosexual women in Poland. At the same time, the obtained results allow for the identification of patterns indicating that older non-heterosexual women may negotiate their sexual and gender identity throughout their lives. As a result, it is easier for them not to succumb to stereotypically directed social expectations regarding appearance and sexual expression aimed at women.

目的:该研究的目的是呈现的身体形象,年龄50岁以上的妇女生活在波兰与宣布的非异性恋取向在老龄化,更年期,性和性别认同的背景下。方法:对50-67岁的非异性恋顺性女性进行深入的半结构化访谈,主要围绕三个方面:更年期、身体形象和衰老。结果:主题分析允许确定两个主要主题领域:(1)更年期与身体的重新整合,(2)从异性恋的女性气质中解脱出来。此外,在第二个主题中,确定了一个子类别:协商性别认同-非二元女同性恋。结论:对叙述的分析表明,在波兰非异性恋妇女经历衰老和更年期的巨大多样性中,保留了积极的身体形象。与此同时,获得的结果允许识别模式,表明老年非异性恋妇女可能在其一生中协商其性和性别身份。因此,他们更容易不屈从于社会对女性外表和性表达的刻板印象。
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引用次数: 0
Psychometric properties of the Polish version of The Comprehensive Assessment of Acceptance and Commitment Therapy Processes (CompACT). 波兰版《接受与承诺治疗过程综合评估》(CompACT)的心理测量特性。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-08-31 DOI: 10.12740/PP/193087
Joanna Dudek, Maria Cyniak-Cieciura, Paweł Ostaszewski

Objectives: The aim of the study was to translate and validate the Polish version of the Comprehensive Assessment of Acceptance and Commitment Therapy Processes (CompACT). This is a self-report questionnaire used to assess psychological flexibility, including three scales: "Openness to Experience", "Behavioural Awareness" and "Valued Action".

Methods: A total of 791 individuals (423 women; 53.5%) aged 18-84, participated in the study. Additional data was gathered on life-satisfaction, the level of depression, anxiety and stress, psychological inflexibility, cognitive fusion, contact with present moment, self-perception, committed action, and valued living as the source of theoretical validity.

Results: The internal structure of the full 23-item version was not confirmed (analogically as in the studies on the original version). The internal structure of the shorter 18-item version of the CompACT was confirmed, and a new 9-item version was proposed. Both versions (18-item and 9-item) exhibited good psychometric properties, incremental validity and measurement invariance across gender.

Conclusions: CompACT-18 and CompACT-9 are reliable and valid tools to measure psychological flexibility and its three components.

目的:本研究的目的是翻译和验证波兰语版的接受和承诺治疗过程综合评估(CompACT)。这是一份自我报告问卷,用于评估心理灵活性,包括三个量表:“经验开放性”、“行为意识”和“价值行动”。方法:共有791人(女性423人,占53.5%),年龄在18-84岁之间。研究人员还收集了生活满意度、抑郁程度、焦虑和压力、心理不灵活性、认知融合、与当前时刻的联系、自我感知、承诺行动和有价值的生活等方面的数据,作为理论有效性的来源。结果:未确定完整的23项版本的内部结构(类似于原始版本的研究)。确定了《契约》较短的18项版本的内部结构,并提出了一个新的9项版本。18题和9题两个版本均表现出良好的心理测量特性、递增效度和跨性别测量不变性。结论:CompACT-18和CompACT-9是测量心理灵活性及其三个组成部分的可靠有效的工具。
{"title":"Psychometric properties of the Polish version of The Comprehensive Assessment of Acceptance and Commitment Therapy Processes (CompACT).","authors":"Joanna Dudek, Maria Cyniak-Cieciura, Paweł Ostaszewski","doi":"10.12740/PP/193087","DOIUrl":"https://doi.org/10.12740/PP/193087","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to translate and validate the Polish version of the Comprehensive Assessment of Acceptance and Commitment Therapy Processes (CompACT). This is a self-report questionnaire used to assess psychological flexibility, including three scales: \"Openness to Experience\", \"Behavioural Awareness\" and \"Valued Action\".</p><p><strong>Methods: </strong>A total of 791 individuals (423 women; 53.5%) aged 18-84, participated in the study. Additional data was gathered on life-satisfaction, the level of depression, anxiety and stress, psychological inflexibility, cognitive fusion, contact with present moment, self-perception, committed action, and valued living as the source of theoretical validity.</p><p><strong>Results: </strong>The internal structure of the full 23-item version was not confirmed (analogically as in the studies on the original version). The internal structure of the shorter 18-item version of the CompACT was confirmed, and a new 9-item version was proposed. Both versions (18-item and 9-item) exhibited good psychometric properties, incremental validity and measurement invariance across gender.</p><p><strong>Conclusions: </strong>CompACT-18 and CompACT-9 are reliable and valid tools to measure psychological flexibility and its three components.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"59 4","pages":"631-642"},"PeriodicalIF":1.1,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of stress levels and the factors that induce it between medical and dental students in the clinical years of their training. 医学与牙科学生临床实习期间压力水平及诱发因素的比较。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-08-31 DOI: 10.12740/PP/191858
Urszula Maria Marchewka, Wojciech Marchewka, Lech Popiołek, Krzysztof Bryniarski

Objectives: The aim of our study was to acknowledge the levels of stress, the main stressors and the difficulties of being a dentistry and medicine student.

Methods: A total of 994 clinical students from both dental and medical undergraduate degrees at Jagiellonian University Medical College in Kraków, Poland were enrolled in the study, of whom 830 were medical and 164 were dental students. We used two independent international stress questionnaires, both validated for the Polish translation and environment: the Perceived Stress Scale and the Perceived Medical School Stress Instrument.

Results: Both medical and dental students had high levels of stress: 20.9 ± 7.37 and 21.24 ± 6.84, respectively. The level of stress was slightly higher among dental students, however, the results were not significant (p = 0.767). Dental students significantly more often were concerned that they will not be able to endure the long hours and responsibilities associated with clinical training (p = 0.001), however, medical student significantly more often agreed that medical school fosters a sense of anonymity and feelings of isolation among the students (p = 0.01).

Conclusions: Polish clinical medical and dental students experience high levels of stress, which is slightly higher among dental ones.

目的:本研究的目的是了解作为一名牙科和医学学生的压力水平、主要压力源和困难。方法:选取波兰Kraków雅盖隆大学医学院牙科和医学本科临床专业994名学生,其中医学专业830名,牙科专业164名。我们使用了两份独立的国际压力问卷,均针对波兰语翻译和环境进行了验证:感知压力量表和感知医学院压力工具。结果:医学生和牙科学生的应激水平均较高,分别为20.9±7.37和21.24±6.84。牙科学生的压力水平略高,但差异无统计学意义(p = 0.767)。牙科专业的学生明显更多地担心他们将无法忍受与临床训练相关的长时间工作和责任(p = 0.001),然而,医科专业的学生明显更多地认为医学院培养了学生的匿名感和孤立感(p = 0.01)。结论:波兰临床医学和牙科专业学生的压力水平较高,而牙科专业学生的压力水平略高。
{"title":"Comparison of stress levels and the factors that induce it between medical and dental students in the clinical years of their training.","authors":"Urszula Maria Marchewka, Wojciech Marchewka, Lech Popiołek, Krzysztof Bryniarski","doi":"10.12740/PP/191858","DOIUrl":"https://doi.org/10.12740/PP/191858","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of our study was to acknowledge the levels of stress, the main stressors and the difficulties of being a dentistry and medicine student.</p><p><strong>Methods: </strong>A total of 994 clinical students from both dental and medical undergraduate degrees at Jagiellonian University Medical College in Kraków, Poland were enrolled in the study, of whom 830 were medical and 164 were dental students. We used two independent international stress questionnaires, both validated for the Polish translation and environment: the Perceived Stress Scale and the Perceived Medical School Stress Instrument.</p><p><strong>Results: </strong>Both medical and dental students had high levels of stress: 20.9 ± 7.37 and 21.24 ± 6.84, respectively. The level of stress was slightly higher among dental students, however, the results were not significant (p = 0.767). Dental students significantly more often were concerned that they will not be able to endure the long hours and responsibilities associated with clinical training (p = 0.001), however, medical student significantly more often agreed that medical school fosters a sense of anonymity and feelings of isolation among the students (p = 0.01).</p><p><strong>Conclusions: </strong>Polish clinical medical and dental students experience high levels of stress, which is slightly higher among dental ones.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"59 4","pages":"597-611"},"PeriodicalIF":1.1,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methods of preventing postpartum depression. The role of physical activity, mobile applications and psychosocial interventions. 预防产后抑郁症的方法。身体活动、移动应用程序和社会心理干预的作用。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-08-31 DOI: 10.12740/PP/OnlineFirst/193252
Adrianna Falenta, Natalia Droździok, Magdalena Piegza

Introduction: The purpose of this narrative review is to collect and analyze research on selected methods of preventing postpartum depression.

Material and methods: The literature review for this work was carried out in the scientific database PubMed. The analysis and further description were developed based on the PRISMA protocol. Only English-language research, published between 2018 and 2023 were included.

Results: Research has not definitively proved a correlation between physical activity and preventing postpartum depression. The effective strategies that may reduce the risk of postpartum depression include mindfulness meditation, providing pregnant women with social support and professional medical care, as well as participating in educational programs during pregnancy. Additionally, internet programs and mobile apps based on cognitive-behavioral therapy can be an effective form of psychological support for pregnant women.

Conclusions: There are a few effective strategies that may reduce the risk of postpartum depression. The research has shown that the key is to provide women with holistic and multidisciplinary care, as well as identifying groups at highest risk of postpartum depression, in order to offer them professional support as quickly as possible.

前言:本文的目的是收集和分析有关预防产后抑郁的方法的研究。材料和方法:本工作的文献综述在PubMed科学数据库中进行。根据PRISMA协议进行分析和进一步描述。仅包括2018年至2023年间发表的英语研究。结果:研究还没有明确证明体育锻炼和预防产后抑郁症之间的联系。减少产后抑郁风险的有效策略包括正念冥想,为孕妇提供社会支持和专业医疗护理,以及在怀孕期间参加教育项目。此外,基于认知行为疗法的互联网程序和移动应用程序可以成为孕妇心理支持的有效形式。结论:有一些有效的策略可以降低产后抑郁的风险。研究表明,关键是为妇女提供全面和多学科的护理,以及确定产后抑郁症风险最高的群体,以便尽快为她们提供专业支持。
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引用次数: 0
Cannabis and cannabinoids in the treatment of post-traumatic stress disorder: A literature review and analysis of the content of websites of Polish clinics specializing in medical marijuana treatment. 大麻和大麻素治疗创伤后应激障碍:波兰专门从事医用大麻治疗的诊所网站内容的文献综述和分析。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-08-31 DOI: 10.12740/PP/192416
Patrycja Kurowska, Cezary Wojtyła, Anna Królak, Janusz Ostrowski, Wojciech Giermaziak

The latest scientific literature shows that the incidence of post-traumatic stress disorder (PTSD) in Poland has increased significantly. The rise in the number of people affected by PTSD translates into a growing demand for specialist support and treatment of this disease entity. Polish clinics specialising in therapy with the so-called medical marijuana (MM) describe it as a raw material with potential for the treatment of PTSD and an alternative to conventional treatment methods. The paper presents the basic medicines used in PTSD treatment. The authors carried out a review of the literature evaluating the efficacy and safety of cannabis and cannabinoids in the treatment of PTSD. In addition, the article refers to papers highlighting the negative mental health consequences of marijuana use, with particular emphasis on its impact on the course of PTSD. Previously published studies relating the attitudes of psychiatrists towards the use of MM are also discussed. The manner of presenting the potential of Cannabis sp. and their products in the treatment of PTSD on the websites of Polish medical marijuana clinics was analysed, discussed and critically evaluated. Currently, there is no sufficient solid evidence to recommend MM or cannabinoids to treat PTSD, but people struggling with this disorder reach for Cannabis sp. products for their anxiolytic, sedative, hypnotic, and antipsychotic effects. In anticipation of new data from randomised, large-scale, controlled trials, it is advisable to develop available sources of information and appropriate oversight to counteract harmful marketing of medical marijuana.

最新的科学文献表明,波兰创伤后应激障碍(PTSD)的发病率显著增加。受创伤后应激障碍影响的人数的增加转化为对这种疾病实体的专家支持和治疗的不断增长的需求。波兰专门从事所谓医用大麻(MM)治疗的诊所将其描述为一种具有治疗创伤后应激障碍潜力的原料,是传统治疗方法的替代方案。本文介绍了治疗创伤后应激障碍的基本药物。作者对评估大麻和大麻素治疗创伤后应激障碍的有效性和安全性的文献进行了回顾。此外,这篇文章还引用了一些强调大麻使用对心理健康负面影响的论文,特别强调了它对创伤后应激障碍病程的影响。先前发表的有关精神科医生对使用MM的态度的研究也进行了讨论。对在波兰医用大麻诊所网站上介绍大麻公司及其产品在治疗创伤后应激障碍方面的潜力的方式进行了分析、讨论和批判性评价。目前,没有足够的确凿证据推荐MM或大麻素来治疗创伤后应激障碍,但患有这种疾病的人会选择大麻产品,因为它们具有抗焦虑、镇静、催眠和抗精神病作用。在预期从随机、大规模、对照试验中获得新数据的情况下,建议开发可用的信息来源和适当的监督,以抵制有害的医用大麻营销。
{"title":"Cannabis and cannabinoids in the treatment of post-traumatic stress disorder: A literature review and analysis of the content of websites of Polish clinics specializing in medical marijuana treatment.","authors":"Patrycja Kurowska, Cezary Wojtyła, Anna Królak, Janusz Ostrowski, Wojciech Giermaziak","doi":"10.12740/PP/192416","DOIUrl":"https://doi.org/10.12740/PP/192416","url":null,"abstract":"<p><p>The latest scientific literature shows that the incidence of post-traumatic stress disorder (PTSD) in Poland has increased significantly. The rise in the number of people affected by PTSD translates into a growing demand for specialist support and treatment of this disease entity. Polish clinics specialising in therapy with the so-called medical marijuana (MM) describe it as a raw material with potential for the treatment of PTSD and an alternative to conventional treatment methods. The paper presents the basic medicines used in PTSD treatment. The authors carried out a review of the literature evaluating the efficacy and safety of cannabis and cannabinoids in the treatment of PTSD. In addition, the article refers to papers highlighting the negative mental health consequences of marijuana use, with particular emphasis on its impact on the course of PTSD. Previously published studies relating the attitudes of psychiatrists towards the use of MM are also discussed. The manner of presenting the potential of Cannabis sp. and their products in the treatment of PTSD on the websites of Polish medical marijuana clinics was analysed, discussed and critically evaluated. Currently, there is no sufficient solid evidence to recommend MM or cannabinoids to treat PTSD, but people struggling with this disorder reach for Cannabis sp. products for their anxiolytic, sedative, hypnotic, and antipsychotic effects. In anticipation of new data from randomised, large-scale, controlled trials, it is advisable to develop available sources of information and appropriate oversight to counteract harmful marketing of medical marijuana.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"59 4","pages":"577-596"},"PeriodicalIF":1.1,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial. 社论。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-08-31 DOI: 10.12740/PP/210153
Dominika Dudek, Jerzy A Sobański, Katarzyna Klasa

no summary.

没有总结。
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引用次数: 0
期刊
Psychiatria polska
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