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This review aims to summarise the current knowledge on structural brain changes among people diagnosed with gaming disorder and the resulting clinical implications. The review will show the theoretical psychological and neurobiological models of computer gaming disorder in conjunction with the results of structural neuroimaging studies. Previous epidemiological studies indicate that the prevalence of gaming disorder in the population may reach approx. 2%. Researchers indicate that the aetiopathogenesis of computer game use disorder is complex and includes psychological, social, as well as neurological and hormonal factors. From the perspective of psychological research exploring gaming disorder, it can be concluded that a person has certain specific psychopathological features and/or symptoms, which, through mediating factors, such as the inability to cope with stress or negative emotions, influence the formation of the symptoms of the disorder. In the context of the neurobiology of behavioural addictions, researchers point to disorders in the mesocorticolimbic reward system, which is influenced by dysfunctional neuronal mechanisms of emotion and stress regulation. When describing structural changes in the brain, researchers most often report differences in the volume of grey matter, which include areas of the dorsolateral prefrontal cortex, temporooccipital cortex, superior and posterior parietal cortex, anterior cingulate cortex, cerebellum, insular cortex, limbic system, and basal ganglia.
In terms of object relations theory, borderline personality disorder (BPD) is characterized by a structural abnormality of identity, conflicting representations of self and others, and disorganization of attachment - a construct rooted in an individual's early experiences and central to the relationships established later in life. A special role in the formation of attachment style is attributed to the relationship with the caregiver and to difficult experiences or traumas from early developmental stages. These experiences not only provide the psychological basis for the development of an insecure attachment style, but also leave a biological mark in the body in the form of epigenetic modifications. Although research on epigenetic modifications in BPD is scarce, a growing body of evidence supports the importance of oxytocin - the "social peptide" underlying attachment - in the etiology of BPD. We believe that the study of epigenetic modifications that affect the action of oxytocin in the BPD clinical population will provide a better understanding of the basis and process of development of the disorder, as well as provide a therapeutic direction to work effectively in the major areas of BPD.
Objectives: The purpose of this article is to present the authors´ comments on the analysis of the conditions for admitting a person to a psychiatric hospital against their will on the basis of a judgment issued by a guardianship court as part of proceedings initiated at the request of an authorized entity, and the assumptions contained therein are based on applicable normative acts.
Methods: The method of analyzing the current provisions of medical law was used, and of the social security law were also referred to. The judicature of the courts, in particular the Supreme Court, was collected, presented and considered, which constitute a practical guide in assessing whether or not the conditions for admitting a patient to a psychiatric hospital without their consent have been met.
Results: Placing a mentally ill person in a psychiatric hospital without their consent, in a situation where the person does not pose a direct threat to their health and life, or to the health and life of third parties, and does not pose a threat to public safety, is quite a specific restriction of the human right to freedom, sanctioned by the state.
Conclusions: The provision of Article 29 (1) of the Mental Health Act is a special provision, it should be interpreted strictly, without referring to the principles of broad interpretation or analogy, and the supreme directive of the courts' actions should be the requirement that the ruling should be purposeful from the point of view of the good and interest of the person concerned.
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