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Metabolic syndrome in patients who have been subjected to isolation security measures and treated with atypical antipsychotics. 接受隔离安全措施和非典型抗精神病药物治疗的患者的代谢综合征。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-10-31 DOI: 10.12740/PP/OnlineFirst/163553
Przemysław Cynkier, Inga Markiewicz, Grzegorz Kudlak, Dorota Antoniak, Janusz Heitzman

Objectives: The main aim of the study was to assess the incidence of metabolic syndrome and its individual components in patients subject to a confinement measure, treated with antipsychotics in mono - or polytherapy. Additional objectives included the analysis of associations between the occurrence of metabolic syndrome and patients' age, psychiatric diagnosis, overweight or obesity, and the presence of addictions to psychoactive substances.

Methods: The study involved 61 patients of the Department of Forensic Psychiatry, including 9 women and 52 men, subject to a confinement measure from September 2019 to August 2021. All parameters of metabolic syndrome and BMI were measured twice, at the beginning of the stay at the Department and after six months of treatment with atypical antipsychotics. Appropriate statistical comparative analyses were then performed.

Results: There was no relationship between the occurrence of metabolic syndrome and the age of the subjects, medical diagnosis, addiction to psychoactive substances, including smoking. It has not been confirmed that the chronic use of atypical antipsychotics with parallel prophylactic and health-promoting effects in conditions of confinement leads to the development of metabolic syndrome and worsens its symptoms, apart from a marked increase in waist circumference and an increase in BMI.

Conclusions: Systematic measurements of BMI and waist circumference during treatment with atypical antipsychotics may be accurate tools in assessing the risk of metabolic syndrome. Long-term confinement hospitalizations should include psychoeducational interventions aimed at minimizing metabolic complications of pharmacotherapy.

目的:本研究的主要目的是评估接受禁闭措施、单药或多药抗精神病药物治疗的患者代谢综合征的发生率及其个体成分。其他目标包括分析代谢综合征的发生与患者年龄、精神诊断、超重或肥胖以及精神活性物质成瘾之间的关系。方法:这项研究涉及法医精神病学系的61名患者,其中包括9名女性和52名男性,他们在2019年9月至2021年8月期间接受了禁闭措施。在住院之初和非典型抗精神病药物治疗六个月后,对代谢综合征和BMI的所有参数进行了两次测量。然后进行适当的统计比较分析。结果:代谢综合征的发生与受试者的年龄、医学诊断、精神活性物质成瘾(包括吸烟)无关。尚未证实在禁闭条件下长期使用具有平行预防和促进健康作用的非典型抗精神病药物会导致代谢综合征的发展并恶化其症状,结论:在非典型抗精神病药物治疗期间,系统测量BMI和腰围可能是评估代谢综合征风险的准确工具。长期住院治疗应包括心理教育干预,旨在最大限度地减少药物治疗的代谢并发症。
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引用次数: 0
Editorial. 社论。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-10-31 DOI: 10.12740/PP/195990
Dominika Dudek, Jerzy A Sobański, Katarzyna Klasa

no summary.

没有总结。
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引用次数: 0
Symptoms of sexuality-related disorders in the group of overweight and obese women. 超重和肥胖女性的性相关障碍症状。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-10-31 DOI: 10.12740/PP/OnlineFirst/162429
Anna Fuksiewicz, Barbara Kostecka, Emilia Kot, Aleksandra Jodko-Modlińska, Katarzyna Kucharska

Objectives: The aim of the study was to assess the presence of symptoms of sexuality-related disorders (S-RD) in a group of overweight and obese women and the relationship of these symptoms with maladaptive attitudes and beliefs about food, the severity of anxiety and depressive symptoms, alcohol consumption, difficulties in emotional regulation, and the general quality of life.

Methods: The study group (SG) consisted of 44 overweight/obese women, the control group (CG) consisted of 51 women with normal body weight, all aged 18-40 years. The following were used: Sexological Questionnaire, Eating Attitude Test, Eating Beliefs Questionnaire, Alcohol Use Disorder Identification Test, Hospital Anxiety and Depression Scale, and the Quality of Life Questionnaire.

Results: SG showed more severe S-RD symptoms, including sexual dysfunctions and sexual preferences disorders, as compared to CG. In the SG there were more significant correlations between S-RD and the studied variables, especially in the area of difficulties with emotional regulation. Negative and permissive dietary beliefs were significant for S-RD in SG, while positive beliefs were significant in CG. Additionally, the number of S-RD symptoms predicted the quality of life.

Conclusions: The results indicate a relationship between excessive body weight and greater severity of S-RD symptoms, as well as a relationship between the symptoms of S-RD with clinical variables and with the quality of life. Further research exploring the mechanisms of the observed relationships is necessary.

目的:本研究的目的是评估一组超重和肥胖女性性相关障碍(S-RD)症状的存在,以及这些症状与对食物的不适应态度和信念、焦虑和抑郁症状的严重程度、饮酒、情绪调节困难和总体生活质量的关系。方法:研究组(SG)由44名超重/肥胖女性组成,对照组(CG)由51名体重正常的女性组成,年龄均为18-40岁。结果:与CG相比,SG表现出更严重的S-RD症状,包括性功能障碍和性偏好障碍。在SG中,S-RD与研究变量之间存在更显著的相关性,尤其是在情绪调节困难的领域。消极和宽容的饮食信念对SG的S-RD有显著影响,而积极的信念对CG有显著影响。此外,S-RD症状的数量可以预测生活质量。结论:e结果表明,超重与S-RD症状的严重程度之间存在关系,S-RD症状与临床变量和生活质量之间也存在关系。有必要对观察到的关系的机制进行进一步的研究。
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引用次数: 0
The notion and practice of psychotherapy in Polish psychiatry of the interwar period. Part 1. 战时波兰精神病学中心理疗法的概念和实践。第 1 部分.
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/172864
Jan Kornaj, Andrzej Pankalla

The paper explores the development of psychotherapy in Polish psychiatry in the interwar period from the perspective of Kurt Danziger's historical psychology. Firstly, the organizational and social context of the development of Polish psychiatric care in the interwar period and its impact on the development of psychotherapy is outlined. Then, the most influential in Poland, European psychotherapeutic developments in the interwar period are reconstructed. Finally, the views of psychiatric personnel of three psychiatric facilities proposing psychotherapy as one of the main means of treatment of mentally ill patients are introduced: Dziekanka Psychiatric Hospital, the Jewish Hospital in Warsaw and Psychiatry and Neuropathology Clinic of the Jagiellonian University in Krakow. Psychiatric personnel from Dziekanka Psychiatric Hospital, directed by Aleksander Piotrowski, understood psychotherapy broadly, as the influence of the environment on the patient's psyche. Psychiatrists of the Jewish Hospital in Warsaw, Adam Wizel, Gustaw Bychowski, Władysław Matecki, and Maurycy Bornsztajn developed psychoanalytically influenced psychotherapy of schizophrenia. Bychowski also advocated for the application of psychotherapy in such neglected groups of patients as children and the intellectually disabled. Jan Piltz and Eugeniusz Artwiński pursued psychotherapy in the treatment of war neuroses at the Psychiatry and Neuropathology Clinic of the Jagiellonian University.

本文从库尔特-丹齐格(Kurt Danziger)的历史心理学角度探讨了波兰精神病学在战时的心理治疗发展。首先,概述了战时波兰精神病治疗发展的组织和社会背景及其对心理疗法发展的影响。然后,重构了战时在波兰最具影响力的欧洲心理治疗发展。最后,介绍了三家精神病院的精神科人员的观点,他们建议将心理疗法作为治疗精神病患者的主要手段之一:Dziekanka 精神病院、华沙犹太医院和克拉科夫雅盖隆大学精神病学和神经病理学诊所。由亚历山大-皮奥特罗斯基(Aleksander Piotrowski)领导的 Dziekanka 精神病医院的精神科人员将心理治疗广义地理解为环境对病人心理的影响。华沙犹太医院的精神科医生亚当-维泽尔(Adam Wizel)、古斯塔夫-拜霍夫斯基(Gustaw Bychowski)、瓦迪斯瓦夫-马特茨基(Władysław Matecki)和毛里西-博恩斯塔因(Maurycy Bornsztajn)发展了受精神分析影响的精神分裂症心理疗法。Bychowski 还主张将心理疗法应用于儿童和智障等被忽视的患者群体。Jan Piltz 和 Eugeniusz Artwiński 在雅盖隆大学精神病学和神经病理学诊所开展了治疗战争神经官能症的心理疗法。
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引用次数: 0
An outline of savant syndrome. 天才综合症概述
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/OnlineFirst/157104
Gracjan Rudziński, Kinga Pożarowska, Kinga Brzuszkiewicz, Ewelina Soroka

This article is a review of research on savant syndrome from years 2000-2022 - available in PubMed, ResearchGate and Google Scholar databases. Savant syndrome occurs with a frequency of 1.4 per 1,000 people with intellectual disabilities and in 10% of people with a diagnosis of autism spectrum disorders. Autism is the disorder that most often co-occurs with savant syndrome - in about 50% of all people with a savant syndrome diagnosis. Researchers distinguish between: congenital savant syndrome - which affects about 90% of people with the syndrome, and acquired savant syndrome - which occurs in the course of frontotemporal dementia or in people who have experienced trauma to the central nervous system. There are many cognitive theories that explain savant abilities. The anatomical basis of this entity has not been discovered using neuroimaging techniques. To date, no unified theory has been created that reliably explains the etiology and pathomechanism of savant syndrome. Previous neuroimaging studies of people with symptoms of savant syndrome have been conducted on too few subjects. There are indications that magnetic brain stimulation may contribute to a better understanding of the neurophysiological basis of this syndrome.

本文是对 2000-2022 年间有关天赋综合症研究的综述,可在 PubMed、ResearchGate 和 Google Scholar 数据库中查阅。天才综合症的发病率为每 1,000 名智障人士中 1.4 人,在被诊断患有自闭症谱系障碍的人群中占 10%。自闭症是最常与天赋综合症并发的疾病,在所有被诊断患有天赋综合症的人中,自闭症患者约占 50%。研究人员将精明能干综合症分为先天性精明能干综合症和后天性精明能干综合症,先天性精明能干综合症约影响 90% 的精明能干综合症患者,后天性精明能干综合症则发生在额颞叶痴呆或中枢神经系统受过创伤的人身上。有许多认知理论可以解释天赋能力。使用神经成像技术尚未发现这一实体的解剖学基础。迄今为止,还没有一种统一的理论能够可靠地解释 "天才综合症 "的病因和病理机制。以前对有天赋综合征症状的人进行的神经影像学研究对象太少。有迹象表明,脑磁刺激可能有助于更好地了解这种综合征的神经生理基础。
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引用次数: 0
Use of the opioid receptor antagonist - naltrexone in the treatment of non-suicidal self-injury. 使用阿片受体拮抗剂--纳曲酮治疗非自杀性自伤。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/OnlineFirst/161954
Hanna Karakuła-Juchnowicz, Agnieszka Banaszek, Dariusz Juchnowicz

Aim: The aim of the study was to review the existing research, conducted on animal and human models, regarding the possibility of using low doses of naltrexone (LDN) in treatment of non-suicidal self-injury (NSSI).

Method: The available Polish - and English-language literature on NSSI was reviewed. Relevant studies were identified through an electronic search of PubMed/MEDLINE and Google Scholar databases using the following keywords: non-suicidal self-injury, NSSI, naltrexone, LDN, self-injury, self-harm, and time descriptors 1982-2022. The review was based on information reported in original papers, review articles and case reports. The quality of the article was assessed using the six-point Scale for the Assessment of Narrative Review Articles (SANRA).

Results: Studies conducted on animal models show that use of LDN can prevent habitual self-injury. As far as the possibility of clinical use of LDN in treatment of NSSI is concerned, results of a relatively small number of studies conducted so far confirm the efficacy of using naltrexone 25-50 mg/day to decrease or eliminate self-injurious behaviors in NSSI patients.

Conclusions: The use of LDN in treatment of NSSI seems to be a promising clinical option, whose efficacy, however, needs to be corroborated in a larger number of randomized placebo-controlled clinical trials.

目的:本研究旨在回顾现有的动物和人体模型研究,探讨使用低剂量纳曲酮(LDN)治疗非自杀性自伤(NSSI)的可能性:方法:对现有的关于 NSSI 的波兰语和英语文献进行了审查。通过使用以下关键词在 PubMed/MEDLINE 和 Google Scholar 数据库中进行电子检索,确定了相关研究:非自杀性自伤、NSSI、纳曲酮、LDN、自伤、自残,时间描述为 1982-2022 年。综述以原始论文、综述文章和病例报告中报告的信息为基础。文章质量采用叙事性评论文章六分评估表(SANRA)进行评估:在动物模型上进行的研究表明,使用 LDN 可以预防习惯性自伤。就临床使用 LDN 治疗 NSSI 的可能性而言,目前进行的相对较少的研究结果证实,使用纳曲酮 25-50 毫克/天可有效减少或消除 NSSI 患者的自伤行为:使用 LDN 治疗 NSSI 似乎是一种很有前景的临床选择,但其疗效还需要更多的随机安慰剂对照临床试验来证实。
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引用次数: 0
The notion and practice of psychotherapy in Polish psychiatry of the interwar period. Part 2. 战时波兰精神病学中心理疗法的概念和实践。第 2 部分.
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/174212
Jan Kornaj, Andrzej Pankalla

The paper further explores the development of psychotherapy in Polish psychiatry in the interwar period. Jaroszyński attempted to sketch out the idea of "emotional psychotherapy". Stryjeński organized a counseling clinic for the mentally ill, using psychotherapy as one of the means of treatment. Bilikiewicz developed oneiroanalysis - a psychotherapeutic method of dream analysis based on modifications of psychoanalysis. Gottliebowa advocated for the use of psychoanalytically influenced psychotherapy in the gynaecologist practice. Markuszewicz considered psychoanalysis the only psychotherapeutic modality aimed at unearthing the real causes of mental illnesses. Henryk Higier proposed to consider psychoanalysis practically as a method of psychotherapy and saw its heterogeneity as its advantage. Critical views on psychoanalysis as a psychotherapeutic method were delivered by Wirszubski and Mikulski. In general, psychotherapy in Polish psychiatry of the interwar period was highly influenced by psychoanalysis. Moreover, the understanding and practice of psychotherapy in public psychiatric facilities differed from that in private practice. In public psychiatric facilities, it was used mainly to deal with psychoses, so it urged clinicians to modify the classic psychoanalytic approach. In private practice, psychiatrists were dealing mainly with cases of neuroses and therefore could apply standard psychoanalytic procedures. Methods of suggestion, persuasion and hypnosis, characteristic of nineteenth-century psychotherapy, were still in use in Polish psychiatry of the interwar period. The main obstacles to the development of Polish psychotherapy in the interwar period were antisemitic attitudes contributing to hostility towards psychoanalysis, as well as the biological orientation of the majority of the Polish psychiatric society.

本文进一步探讨了战时波兰精神病学中心理疗法的发展。雅罗斯钦斯基试图勾勒出 "情感心理疗法 "的概念。Stryjeński 组织了一个精神病患者咨询诊所,将心理疗法作为治疗手段之一。Bilikiewicz 在对精神分析进行修改的基础上,提出了一种梦境分析的心理治疗方法--"oneiroanalysis"。Gottliebowa 主张在妇科医生的工作中使用受精神分析影响的心理疗法。Markuszewicz 认为精神分析是唯一一种旨在揭示精神疾病真正原因的心理治疗方法。Henryk Higier 提议将精神分析实际视为一种心理治疗方法,并认为精神分析的异质性是其优势所在。Wirszubski 和 Mikulski 对精神分析作为一种心理治疗方法提出了批评意见。总的来说,战时波兰精神病学中的心理疗法深受精神分析的影响。此外,公立精神病院对心理疗法的理解和实践与私人诊所有所不同。在公立精神病院,心理治疗主要用于治疗精神病,因此促使临床医生修改经典的精神分析方法。在私人诊所,精神科医生主要处理神经官能症病例,因此可以采用标准的精神分析程序。十九世纪心理疗法所特有的暗示、说服和催眠方法,在战时的波兰精神病学中仍在使用。波兰心理疗法在战时发展的主要障碍是反犹主义态度导致的对精神分析的敌意,以及波兰精神病学界大多数人的生物学取向。
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引用次数: 0
Efficacy and safety of aripiprazole in the treatment of delirium. 阿立哌唑治疗谵妄的疗效和安全性。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/OnlineFirst/156262
Marcin Jarosz, Karina Aagnieszka Badura Brzoza

Delirium is a disorder of consciousness and it is caused by acute brain disfunction in the course of, e.g., severe somatic condition, intoxication or withdrawal syndrome. Delirium management is based on the treatment of the state that caused disturbance in central nervous system. Severe delirium syndromes such as agitation, disorganized behavior or hallucinations require additional pharmacological treatment with antypsychotics. Aripiprazole is used in treatment of schizophrenia, bipolar disorder and Tourette syndrome, but also off-label in delirium. A systematic review of databases was carried out and results were limited to case reports, clinical trials and randomized controlled trials. There is evidence that there is no difference in effectiveness of aripiprazole compared to haloperidol and other atypical neuroleptics. Aripirazole could be a better option in particular groups of patients due to its safer cardiological and metabolic profile as well as better tolerance of treatment. However, data from clinical findings are still insufficient to recommend a routine use of aripiprazole in the treatment of delirium. Therefore, further investigations are necessary to work out new strategy of managing delirium syndrome.

谵妄是一种意识障碍,由严重躯体疾病、中毒或戒断综合征等过程中的急性脑功能紊乱引起。谵妄治疗的基础是治疗导致中枢神经系统紊乱的状态。严重的谵妄综合征,如躁动、行为紊乱或幻觉,需要额外使用抗精神病药物进行药物治疗。阿立哌唑可用于治疗精神分裂症、双相情感障碍和抽动秽语综合征,也可在标签外用于谵妄。我们对数据库进行了系统性审查,结果仅限于病例报告、临床试验和随机对照试验。有证据表明,与氟哌啶醇和其他非典型神经安定药相比,阿立哌唑的疗效没有差异。由于阿立哌唑在心脏病学和新陈代谢方面更安全,而且对治疗的耐受性更好,因此对于特定的患者群体来说,阿立哌唑可能是更好的选择。然而,临床发现的数据仍不足以建议常规使用阿立哌唑治疗谵妄。因此,有必要开展进一步的研究,以制定治疗谵妄综合征的新策略。
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引用次数: 0
Psychiatrist's opinion as a premise for legal termination of pregnancy. 将精神病医生的意见作为合法终止妊娠的前提。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/186637
Małgorzata Urban-Kowalczyk, Rafał Kubiak

The article presents the provisions currently in force in Polish legislation regarding legal termination of pregnancy. In particular, it refers to the premise of a psychiatrist's decision that the health of a pregnant woman is at risk. Under Polish law, termination of pregnancy is generally prohibited and penalized. However, there are two exceptions to this prohibition. Such a procedure is permitted if: the pregnancy poses a threat to the life or health of the pregnant woman, or if there is a reasonable suspicion that the pregnancy was the result of a prohibited act. The text presents an overview of the relevant regulations and tips on their interpretation and application in everyday medical practice. This issue is particularly important for psychiatrists consulting maternity wards. In addition, the most important mental disorders related to pregnancy and childbirth are described. The clinical features and prevalence of perinatal mood disorders and psychoses are presented. The issue of suicide among pregnant and postpartum patients was also discussed. A sample certificate template was proposed, and guidelines were discussed as to what information and conclusions should be included in the opinion of a psychiatrist.

文章介绍了波兰现行法律中关于合法终止妊娠的规定。特别是,它提到了精神科医生决定孕妇健康受到威胁的前提。根据波兰法律,终止妊娠一般是被禁止的,并会受到惩罚。但是,这项禁令有两个例外。在以下情况下,允许终止妊娠:妊娠对孕妇的生命或健康构成威胁;或有理由怀疑妊娠是违禁行为的结果。本文概述了相关法规,并就其在日常医疗实践中的解释和应用提供了提示。这个问题对于为产科病房提供咨询的精神科医生尤为重要。此外,还介绍了与妊娠和分娩有关的最重要的精神障碍。介绍了围产期情绪障碍和精神病的临床特征和发病率。还讨论了孕妇和产后患者的自杀问题。提出了证书模板样本,并讨论了精神科医生的意见中应包括哪些信息和结论的指导原则。
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引用次数: 0
Study directions and development of cognitive theory of depression. 抑郁症认知理论的研究方向和发展。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-08-31 DOI: 10.12740/PP/OnlineFirst/161676
Krystyna Golonka, Elżbieta Piątek, Ryszard Stach

Aaron T. Beck's cognitive model of depression became the basis for the analysis of cognitive factors as significant correlates and predictors of depression. Psychological mechanisms of depression related to the depressive cognitive triad, the specificity of cognitive schemas and errors in cognitive processing determined the directions of further research on depression. The presented analysis of selected studies confirms and extends Beck's assumptions about the role of cognitive factors in the development and maintenance of depressive symptoms. The analysis of psychological, neuroimaging and biochemical studies provides a broader perspective of understanding both the etiology and mechanisms that sustain the symptoms of depression. The development of neuroimaging research has broadened the knowledge about the brain mechanisms of depression - the presented research combine the theoretical constructs of the cognitive concept of depression with the characteristics of the activity of brain structures and their functional connections. The following conclusions seem to be particularly important for clinical practice: 1) impairment of the cognitive inhibition function in depression reduces the control of negative automatic thoughts - strengthening working memory is important; 2) different brain mechanisms for processing rewards and punishments in people suffering from depression and in healthy people explain the formation of self-esteem - this knowledge can be an important element of psychoeducation in therapeutic work; 3) neuroimaging studies indicate neuronal correlates of cognitive distortions observed in depression - for further research on depression, it would be particularly important to monitor changes in brain activity in the course of its treatment.

亚伦-贝克(Aaron T. Beck)的抑郁认知模型成为分析作为抑郁重要相关因素和预测因素的认知因素的基础。与抑郁认知三要素相关的抑郁心理机制、认知图式的特异性和认知处理过程中的错误决定了抑郁症进一步研究的方向。本文对部分研究的分析证实并扩展了贝克关于认知因素在抑郁症状的发展和维持中的作用的假设。对心理学、神经影像学和生化研究的分析为理解抑郁症状的病因和维持机制提供了更广阔的视角。神经影像学研究的发展拓宽了人们对抑郁症大脑机制的认识--这些研究将抑郁症认知概念的理论构建与大脑结构及其功能连接的活动特征相结合。以下结论似乎对临床实践尤为重要:1)抑郁症患者的认知抑制功能受损,降低了对消极自动思维的控制能力--加强工作记忆非常重要;2)抑郁症患者和健康人处理奖惩的大脑机制不同,解释了自尊的形成原因--这些知识可以成为治疗工作中心理教育的重要内容;3)神经影像学研究表明,抑郁症患者的认知扭曲与神经元相关--对抑郁症的进一步研究而言,监测治疗过程中大脑活动的变化尤为重要。
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