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Co-occurrence of psychopathological symptom severity and personality predisposition in post-traumatic stress disorder in patients several months after hospitalisation due to COVID-19. COVID-19患者住院数月后创伤后应激障碍精神病理症状严重程度与人格易感性的共现
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-06-30 DOI: 10.12740/PP/OnlineFirst/183127
Barbara Bętkowska-Korpała, Katarzyna Olszewska-Turek, Anna Pastuszak-Draxler, Anna Laskowska-Wronarowicz, Jolanta Walczewska, Anna Starowicz-Filip, Dominika Dudek

Objectives: The study's aim was to determine co-occurrence of psychopathological symptoms and personality predispositions in post-traumatic stress disorder (PTSD) and its dimensions several months after hospitalisation of patients with severe COVID-19 during the 2nd and 3rd waves of the epidemic.

Methods: At 7-8 months after admission, 138 patients completed the PCL-5 and TIPI questionnaires, as well as the HADS and AIS scales. Correlation analysis and stepwise multiple regression analysis were used in the models.

Results: 22.5% of patients met the PTSD criteria. There were no significant differences between women and men in terms of severity of anxiety, depression, sleep disorders, distress and PTSD. Anxiety, sleep disorders and depression co-occurred with PTSD severity. All dimensions of PTSD were associated with anxiety. Intrusion, changes in arousal and reactivity correlated with sleep disorders. Changes in arousal and reactivity were explained by subjective assessment of distress. Negative changes in cognition and mood were related to depression and low levels of extraversion.

Conclusions: There is a co-occurrence of the severity of psychopathological symptoms: anxiety, depression, distress and sleep disorders with the severity of PTDS and its dimensions among patients who have undergone severe COVID-19 in the recent past. A protective factor against post-hospitalisation PTSD is higher level of extraversion.

目的:本研究旨在确定在第二波和第三波疫情期间,严重COVID-19患者住院几个月后,创伤后应激障碍(PTSD)中精神病理症状和人格倾向的共现情况及其维度。方法:138例患者于入院后7 ~ 8个月完成PCL-5、TIPI问卷及HADS、AIS量表。模型采用相关分析和逐步多元回归分析。结果:22.5%的患者符合PTSD标准。在焦虑、抑郁、睡眠障碍、痛苦和创伤后应激障碍的严重程度方面,男女之间没有显著差异。焦虑、睡眠障碍和抑郁与PTSD严重程度同时发生。创伤后应激障碍的所有维度都与焦虑有关。干扰,觉醒和反应的变化与睡眠障碍有关。唤醒和反应性的变化可以通过对痛苦的主观评估来解释。认知和情绪的消极变化与抑郁和低外向性有关。结论:近期重症COVID-19患者焦虑、抑郁、苦恼、睡眠障碍等精神病理症状的严重程度与PTDS的严重程度及其维度存在共现关系。较高水平的外向性是预防住院后PTSD的一个保护性因素。
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引用次数: 0
Comparison of depressive symptoms between patients with myeloproliferative neoplasms without the Philadelphia chromosome treated with interferon alpha and patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors. 无费城染色体骨髓增殖性肿瘤患者用干扰素治疗与慢性骨髓性白血病患者用酪氨酸激酶抑制剂治疗抑郁症状的比较
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-06-07 DOI: 10.12740/PP/OnlineFirst/202763
Katarzyna Gibek, Tomasz Sacha

Objectives: The aim of the study was to compare the occurrence of depressive symptoms between a group of patients with MPN (essential thrombocythemia, polycythemia vera, and primary myelofibrosis) treated with interferon-alpha and patients with chronic myelogenous leukaemia (CML) treated with tyrosine kinase inhibitors and to check whether individual side effects may contribute to the occurrence of depressive symptoms.

Methods: The study involved 175 adult patients with MPN and CML who had been treated with IFNα or TKI for a minimum of 3 months. The study used: the David Goldberg Questionnaire (GHQ-28), the Four-Dimensional Questionnaire 4DSQ and our own survey.

Results: Approximately 40% of patients with MPN and almost 20% of patients with CML obtained a moderately and strongly elevated score on the depression scale. The analysis revealed no statistically significant differences between women and men. Bone and joint pain (β=0.196, p=0.013), nausea and indigestion (β=0.191, p=0.007), fatigue (β=0.136, p=0.053), cramps and muscle aches (β=0.159, p=0.038) and diarrhoea (β=0.138, p=0.050) were side effects that affected the possibility of developing depressive symptoms in both groups. The common predictor of depressive symptoms was the number of side effects, the type of illness, and age. The older the person was, the greater the severity of depressive symptoms.

Conclusions: There are significant differences in the prevalence of depression between patients with CML and MPN. Specific side effects of interferon-alpha and TKI treatment influence the occurrence of depressive symptoms. No association between interferon treatment and the development of depression was confirmed.

目的:本研究的目的是比较干扰素- α治疗的MPN(原发性血小板增多症、真性红细胞增多症和原发性骨髓纤维化)患者与酪氨酸激酶抑制剂治疗的慢性髓性白血病(CML)患者之间抑郁症状的发生,并检查个体副作用是否可能导致抑郁症状的发生。方法:该研究纳入175名成年MPN和CML患者,这些患者接受IFNα或TKI治疗至少3个月。研究使用了:大卫·戈德堡问卷(GHQ-28)、四维问卷4DSQ和我们自己的调查。结果:大约40%的MPN患者和近20%的CML患者在抑郁量表上获得中度和重度升高的评分。分析显示,男女之间没有统计学上的显著差异。骨和关节疼痛(β=0.196, p=0.013)、恶心和消化不良(β=0.191, p=0.007)、疲劳(β=0.136, p=0.053)、痉挛和肌肉疼痛(β=0.159, p=0.038)和腹泻(β=0.138, p=0.050)是影响两组出现抑郁症状可能性的副作用。抑郁症状的常见预测因子是副作用的数量、疾病的类型和年龄。年龄越大,抑郁症状越严重。结论:CML与MPN患者抑郁患病率存在显著差异。干扰素- α和TKI治疗的特定副作用影响抑郁症状的发生。没有证实干扰素治疗与抑郁症的发展之间存在关联。
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引用次数: 0
Ketamine - mechanisms of action as an antidepressant. 氯胺酮——抗抑郁药的作用机制。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-06-02 DOI: 10.12740/PP/OnlineFirst/202128
Bronisław Gębik, Katarzyna Bliźniewska-Kowalska, Piotr Gałecki

Since the year 2000, ketamine and its enantiomers have been studied for their antidepressant effects. This paper will briefly summarise the journey of ketamine from an anaesthetic to an antidepressant. The text will present the key mechanisms of its action, as well as the actions of its metabolites. The aim of this article is to describe the role of specific groups of receptors in activation of important metabolic pathways and in production of factors such as mammalian target of rapamycin kinase (mTOR) and brain-derived neurotrophic factor (BDNF), in order to comprehensively present a potential link between ketamine, ketamine's enantiomers and its metabolites with terms such as neuroplasticity and antidepressant action. Another important part of this article is a summary of arguments for and against importance of specific mechanisms of ketamine action and to compare (S) and (R)-ketamine's potential to act as an antidepressant. This article may be particularly helpful for researchers in determining further research directions and serve as a summary of the current state of knowledge regarding the mechanisms of ketamine's action and the latest therapeutic possibilities in the treatment of affective disorders.

自2000年以来,人们一直在研究氯胺酮及其对映体的抗抑郁作用。本文将简要总结氯胺酮从麻醉剂到抗抑郁药的历程。本文将介绍其作用的关键机制,以及其代谢产物的作用。本文的目的是描述特定受体群在重要代谢途径的激活和哺乳动物雷帕霉素激酶靶蛋白(mTOR)和脑源性神经营养因子(BDNF)等因子的产生中的作用,以便全面地介绍氯胺酮、氯胺酮对构象及其代谢物与神经可塑性和抗抑郁作用等术语之间的潜在联系。本文的另一个重要部分是总结支持和反对氯胺酮作用的特定机制的重要性的论点,并比较(S)和(R)-氯胺酮作为抗抑郁药的潜力。这篇文章可能特别有助于研究人员确定进一步的研究方向,并作为对氯胺酮作用机制和治疗情感障碍的最新治疗可能性的知识现状的总结。
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引用次数: 0
Cognitive-Behavioral Therapy for a Patient Diagnosed with Emetophobia - case study. 认知行为疗法治疗一名恐吐症患者个案研究。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-04-30 DOI: 10.12740/PP/188716
Jacek Romański

The aim of this paper is to present the application of cognitive-behavioral therapy in the treatment of emetophobia. The fear of vomiting (emetophobia) is a specific phobia, the mild form affects over 3% of the population, predominantly women. The main symptoms are associ- ated with the fear of experiencing nausea and other gastrointestinal sensations. These sensations are interpreted as a signal of impending vomiting, leading to discomfort and avoidance of eating and social situations. The symptoms may resemble other somatic and psychological disorders and can co-occur with various mental health conditions. The therapy requires an individualized approach and may be more demanding compared to treating other phobias. The article includes a description of the therapy process with an adult patient struggling with emetophobia. Diagnosis was conducted through an interview and the EmetQ-13 questionnaire. The applied therapeutic techniques are presented, along with an understanding of the symptoms considering therapeutic models explaining the development of emetophobia and the mechanisms sustaining it. Key processes playing a crucial role in dysfunction were identified. After 10 sessions of cognitive-behavioral therapy, the patient no longer met the diagnostic criteria for the fear of vomiting, overcoming avoidance behaviors.

本文的目的是介绍认知行为疗法在治疗呕吐恐惧症中的应用。对呕吐的恐惧(呕吐恐惧症)是一种特殊的恐惧症,轻度的形式影响了超过3%的人口,主要是女性。主要症状与对恶心和其他胃肠道感觉的恐惧有关。这些感觉被解释为即将呕吐的信号,导致不适,避免进食和社交场合。这些症状可能类似于其他躯体和心理障碍,并可能与各种精神健康状况同时发生。这种疗法需要个性化的方法,与治疗其他恐惧症相比,可能要求更高。这篇文章描述了一个与呕吐恐惧症作斗争的成年患者的治疗过程。通过访谈和EmetQ-13问卷进行诊断。介绍了应用的治疗技术,以及考虑到解释呕吐恐惧症发展的治疗模式和维持它的机制的症状的理解。确定了在功能障碍中起关键作用的关键过程。经过10次认知行为治疗,患者不再符合呕吐恐惧的诊断标准,克服了回避行为。
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引用次数: 0
Editorial. 社论。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-04-30 DOI: 10.12740/PP/205595
Dominika Dudek, Jerzy A Sobański, Katarzyna Klasa

no summary.

没有总结。
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引用次数: 0
The negative effects of indirect exposure to trauma in therapists working with people with addiction who have experienced traumatic events - the role of empathy and secondary self-efficacy. 间接接触创伤对治疗经历过创伤事件的成瘾者的负面影响——共情和次级自我效能的作用。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-04-30 DOI: 10.12740/PP/189761
Nina Ogińska-Bulik, Zygfryd Juczyński

Objectives: Paradoxically helping others exposes the helpers to secondary traumatization. Its determinants include both factors related to work, as well as individual characteristics. The purpose of this study was to determine the relationships between empathy, secondary self-efficacy, and STS.

Methods: The results obtained from 115 therapists (M age = 40.79; SD = 10.57) working with addicted clients were analysed. Three standard measurement tools were used: the Secondary Traumatic Stress Inventory (STSI), the Empathic Sensitivity Scale (EES), and the Secondary Trauma Self-efficacy (STSE) scale.

Results: Only 15.7% of respondents were found to be at high risk of STS disorders. The main predictor of STS was empathic concern. Secondary self-efficacy partly mediated the relationship between empathic concern and STS. Since the rate of secondary traumatization in the group of therapists is not high compared to other professional groups, it is worth paying attention to factors that protect against STS.

Conclusions: To reduce the risk of disorders resulting from secondary exposure to trauma, personal resources, including self-efficacy, should be developed. It is also useful to develop the ability to cope with the trauma of others by applying self-care practices.

目的:矛盾的是,帮助他人使帮助者暴露于二次创伤。它的决定因素既包括与工作有关的因素,也包括个人特征。本研究旨在探讨共情、二级自我效能感与STS之间的关系。方法:对115名治疗成瘾患者的治疗师(M年龄= 40.79,SD = 10.57)的结果进行分析。采用三种标准测量工具:继发性创伤应激量表(STSI)、共情敏感性量表(EES)和继发性创伤自我效能量表(STSE)。结果:只有15.7%的受访者被发现有STS疾病的高风险。STS的主要预测因子是共情关注。第二自我效能感在共情关怀与STS的关系中起部分中介作用。由于与其他专业群体相比,治疗师群体的继发性创伤率并不高,因此值得关注预防STS的因素。结论:为了降低二次创伤暴露导致的障碍风险,应开发包括自我效能感在内的个人资源。通过自我护理实践,培养应对他人创伤的能力也很有用。
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引用次数: 0
Life satisfaction of carers of people with dementia of the Alzheimer type. 老年痴呆症患者照护者的生活满意度。
IF 1.1 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-04-30 DOI: 10.12740/PP/188810
Anna Sołtys

Objectives: The aim of the study was to look for a correlation between personal resources, care burden and life satisfaction in carers of people with dementia of the Alzheimer type.

Methods: The study involved 100 family and professional carers providing care for a person with dementia of the Alzheimer type. Carers answered survey questions and completed questionnaires: Orientation to Life Questionnaire - SOC-29, Generalised Self-Efficacy Scale (GSES), Social Support Questionnaire (F-SozU K-22), Depression Assessment Questionnaire (KPD), Perceived Stress Questionnaire (KPS), Involvement Evaluation Questionnaire (IEQ) and Satisfaction with Life Scale (SWLS).

Results: Higher levels of a sense of satisfaction with life were observed in carers who had a higher education, were the sole carer of a person with the disease, and who spent less time providing care. Higher levels of available resources and a lower sense of care burden (fewer depressive symptoms, less involvement in care and less stress) were associated with a higher sense of life satisfaction. Depressiveness of carers and high levels of perceived stress reduce the level of satisfaction with life.

Conclusions: Personal resources play an important role among carers in reducing the burden and maintaining proper levels of life satisfaction. The proper management of the resources available to carers is important to counteract the negative consequences of caregiving.

目的:本研究旨在探讨阿尔茨海默型痴呆患者照护者的个人资源、照护负担和生活满意度之间的关系。方法:该研究涉及100名家庭和专业护理人员,他们为阿尔茨海默型痴呆症患者提供护理。照顾者回答调查问题,并填写问卷:生活倾向问卷(SOC-29)、广义自我效能量表(GSES)、社会支持问卷(F-SozU K-22)、抑郁评估问卷(KPD)、感知压力问卷(KPS)、参与评估问卷(IEQ)和生活满意度量表(SWLS)。结果:在那些受过高等教育的护理人员中,对生活的满意度更高,他们是患者的唯一护理人员,并且花较少的时间提供护理。较高的可用资源水平和较低的护理负担感(较少的抑郁症状、较少的护理参与和较少的压力)与较高的生活满意度相关。照顾者的抑郁和高水平的感知压力降低了对生活的满意度。结论:个人资源在减轻照顾者负担和维持适当的生活满意度方面发挥着重要作用。适当管理护理人员可用的资源对于抵消护理的负面后果非常重要。
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引用次数: 0
Letter to the Editorial Office. Institutional Isolation and the Mental Health of Minors in Resocialization Facilities. 给编辑部的信。机构隔离与再社会化机构中未成年人的心理健康
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-02-28 DOI: 10.12740/PP/199866
Anna Dąbrowska
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引用次数: 0
Observing patient rights in the area of psychiatric health care in the era of the COVID-19 pandemic. COVID-19大流行时代精神卫生保健领域患者权利的观察
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-02-28 DOI: 10.12740/PP/175653
Dariusz Zawadzki, Agnieszka Ciastkowska-Berlikowska

Objectives: The work concerns the assessment of compliance with patient rights in the area of psychiatric health care during the COVID-19 pandemic.

Methods: The analysis of compliance with patients' rights was made on the basis of complaints submitted to the Office of the Patient Ombudsman. Reports sent to the Department of Mental Health regarding suspected non-compliance with patient rights were retrospectively analyzed. Structure and dynamics indicators were used to assess changes over time.

Results: After analyzing reports since 2020, we have observed a decrease in the number of cases considered by the Department of Mental Health. In 2021, for all rights, there was a decline in the number of applications processed. According to reports on the observance of patients' rights in the area of psychiatric health care, this may be due to the lack of possibility of personal contact with the Psychiatric Hospital Patient Ombudsman. In addition, during the pandemic, a reduction in the number of cases was observed, which was related to limited access to in-person contact. The scope of reported cases also changed during the pandemic. In the years 2018-2021, most cases concerned assistance in asserting rights in matters related to admission, treatment, conditions of stay and discharge from psychiatric hospitals.

Conclusions: Regarding the scope of applications and complaints considered under the provisions of the Act on Patient Rights and the Patient Ombudsman in 2018-2021, most cases concerned the right to health services, followed by the right to information about one's health and the right to consent to the provision of health services. In the case of applications and complaints considered under the provisions of the Mental Health Protection Act in the years 2018-2021, most cases concerned admission and treatment without consent in a psychiatric hospital, the use of direct coercion in accordance with specific regulations and discharge from the hospital of a person treated with consent.

目的:这项工作涉及评估COVID-19大流行期间精神卫生保健领域对患者权利的遵守情况。方法:根据向患者申诉专员办公室提交的投诉,对患者权利的遵守情况进行分析。对送交精神卫生司的关于疑似不遵守病人权利的报告进行了回顾性分析。结构和动力学指标用于评估随时间的变化。结果:在分析了自2020年以来的报告后,我们观察到精神卫生部门考虑的病例数量有所减少。2021年,就所有权利而言,所处理的申请数量有所下降。根据关于在精神病保健领域尊重病人权利的报告,这可能是由于缺乏与精神病医院病人监察员进行个人接触的可能性。此外,在大流行期间,观察到病例数有所减少,这与面对面接触的机会有限有关。在大流行期间,报告病例的范围也发生了变化。在2018-2021年期间,大多数案件涉及协助维护与精神病院入院、治疗、住院条件和出院有关的权利。结论:关于2018-2021年根据《病人权利法》和病人监察员的规定审议的申请和投诉的范围,大多数案件涉及保健服务权,其次是获得健康信息的权利和同意提供保健服务的权利。在2018-2021年期间根据《精神健康保护法》的规定审议的申请和申诉中,大多数案件涉及未经同意就进入精神病院接受治疗、根据具体条例使用直接胁迫以及经同意接受治疗的人出院。
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引用次数: 0
The influence of the Snoezelen method on postural stability and the risk of falls in people with paranoid schizophrenia. Snoezelen方法对偏执型精神分裂症患者姿势稳定性和跌倒风险的影响。
IF 0.9 4区 医学 Q4 PSYCHIATRY Pub Date : 2025-02-28 DOI: 10.12740/PP/188582
Urszula Żmudzińska, Agnieszka Smrokowska-Reichmann, Anna Ścisłowska-Czarnecka, Magdalena Markowska, Katarzyna Filar-Mierzwa

Objectives: The aim of the study was to describe the changes in the postural stabilisation, quality of life, cognitive functions and behaviour of patients with paranoid schizophrenia who have undergone the Snoezelen therapy and the auctorial sensorimotor exercise program.

Methods: The study was conducted on 55 patients aged 55 to 75 years. Group S underwent therapy in the Snoezelen room for nine weeks, group ES underwent the Snoezelen therapy and were also subjected to auctorial sensorimotor exercise programme, and group C were not given any therapeutic intervention. The Biosway portable balance system, the Berg Balance Scale, Tinetti Test and the Timed Up & Go Test were used to evaluate the effects of the therapy.

Results: In group ES, statistically significant changes were observed in all tested indicators; in group S such changes were observed in the Limit of Stability test, Tinetti Test and TUG test; while in group C, no statistically significant changes were found.

Conclusions: The Snoezelen therapy had a significant impact on changes in postural control rations and a reduced risk of falls. The auctorial sensorimotor exercise programme increased the impact of the Snoezelen room on postural stability measured using the Biosway platform and the risk of falls assessed using the TUG test.

目的:本研究的目的是描述偏执狂型精神分裂症患者在接受Snoezelen治疗和作者感觉运动锻炼计划后的姿势稳定性、生活质量、认知功能和行为的变化。方法:55例患者,年龄55 ~ 75岁。S组在Snoezelen室治疗9周,ES组在接受Snoezelen治疗的同时进行自我感觉运动训练,C组不进行任何治疗干预。使用Biosway便携式平衡系统、Berg平衡量表、Tinetti测试和Timed Up & Go测试来评估治疗效果。结果:ES组各指标变化均有统计学意义;S组的极限稳定性试验、Tinetti试验和TUG试验均观察到上述变化;而C组无统计学差异。结论:Snoezelen治疗对改变体位控制能力和降低跌倒风险有显著影响。作者的感觉运动锻炼计划增加了Snoezelen房间对使用Biosway平台测量的姿势稳定性和使用TUG测试评估的跌倒风险的影响。
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引用次数: 0
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Psychiatria polska
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