Pub Date : 2022-08-10DOI: 10.52711/2321-5836.2022.00034
Prasad. J. Rodge, Mansi B. Rawal, Vinit S. Khairnar
Omicron was first identified in Botswana earlier in November. It was reported to World Health Organization (WHO) from South Africa on November 24, 2021, which was designated as a variant of concern (VOC) on November 26, 2021.The Omicron variant is thought to be at least three times more infectious than the original SARS-CoV-2 and possibly more so than the delta variant. Omicron contains a large number of mutations that were previously reported in other VOCs including at least 32 mutations in the spike protein alone compared to the 16 mutations in the already highly infectious delta variant. europe’s first case of the variant was confirmed in Belgium on 26 November in a person who tested positive for covid-19 on 22 November. By 29 November cases had been reported in the Netherlands, France, Germany, Portugal, and Italy. The UK had recorded nine cases by the morning of 29 November, six of them in Scotland. According to Brihan Mumbai Municipal Corporation (BMC), a 37-year-old man, who landed in Mumbai from South Africa on November 25, was found infected with Omicron along with one of his contacts - a 36-year-old female friend who arrived in the city from the US the same day.
{"title":"Omicron variant [2021-2022]: A new chapter in the COVID-19 Pandemic","authors":"Prasad. J. Rodge, Mansi B. Rawal, Vinit S. Khairnar","doi":"10.52711/2321-5836.2022.00034","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00034","url":null,"abstract":"Omicron was first identified in Botswana earlier in November. It was reported to World Health Organization (WHO) from South Africa on November 24, 2021, which was designated as a variant of concern (VOC) on November 26, 2021.The Omicron variant is thought to be at least three times more infectious than the original SARS-CoV-2 and possibly more so than the delta variant. Omicron contains a large number of mutations that were previously reported in other VOCs including at least 32 mutations in the spike protein alone compared to the 16 mutations in the already highly infectious delta variant. europe’s first case of the variant was confirmed in Belgium on 26 November in a person who tested positive for covid-19 on 22 November. By 29 November cases had been reported in the Netherlands, France, Germany, Portugal, and Italy. The UK had recorded nine cases by the morning of 29 November, six of them in Scotland. According to Brihan Mumbai Municipal Corporation (BMC), a 37-year-old man, who landed in Mumbai from South Africa on November 25, was found infected with Omicron along with one of his contacts - a 36-year-old female friend who arrived in the city from the US the same day.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87405567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-10DOI: 10.52711/2321-5836.2022.00033
Pratiksha S. Bhadane, Ritu M. Khairnar, Shweta S. Gavit
Shampoos are products that remove excess oil, dust on the skin and scalp. Many of the ingredients in shampoos are chemical and that is why they have been severely attacked due to the potential risk of side effects with their use. The main objective of this study was to eliminate the harmful synthetic ingredient in dandruff anti-dandruff and to replace it with safe natural ingredients. An effort has been made to integrate modern formulation technology into a formula based on natural ingredients. The herbal shampoo was prepared with Ritha fruit, Liquorice stolon's, Bengal gram seeds, Brahmi leaves, Green-gram seeds collected in an Ayurvedic store and remained as Banana roots, pomegranate seeds, leaves Hibiscus, Marigold flowers, and lemon fruit and all the ingredients are extracted and create a unique texture and stability tested with Dove shampoo on the market. Formulation 4 was found to be the best method based on the criteria for testing and stability studies. In a review of research data, the development of four anti-dandruff anti-dandruff anti-dandruff products containing all the positive properties of a suitable shampoo and was found to be safe, effective and economical compared to synthetic Dove anti dandruff shampoo, proved to be a stable improvement., an effective herbal anti-dandruff shampoo that may be commercially available instead of an existing synthetic shampoo is possible.
{"title":"To Perform and prepared the Formulation and Evaluation of Herbal Antidandruff Shampoo","authors":"Pratiksha S. Bhadane, Ritu M. Khairnar, Shweta S. Gavit","doi":"10.52711/2321-5836.2022.00033","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00033","url":null,"abstract":"Shampoos are products that remove excess oil, dust on the skin and scalp. Many of the ingredients in shampoos are chemical and that is why they have been severely attacked due to the potential risk of side effects with their use. The main objective of this study was to eliminate the harmful synthetic ingredient in dandruff anti-dandruff and to replace it with safe natural ingredients. An effort has been made to integrate modern formulation technology into a formula based on natural ingredients. The herbal shampoo was prepared with Ritha fruit, Liquorice stolon's, Bengal gram seeds, Brahmi leaves, Green-gram seeds collected in an Ayurvedic store and remained as Banana roots, pomegranate seeds, leaves Hibiscus, Marigold flowers, and lemon fruit and all the ingredients are extracted and create a unique texture and stability tested with Dove shampoo on the market. Formulation 4 was found to be the best method based on the criteria for testing and stability studies. In a review of research data, the development of four anti-dandruff anti-dandruff anti-dandruff products containing all the positive properties of a suitable shampoo and was found to be safe, effective and economical compared to synthetic Dove anti dandruff shampoo, proved to be a stable improvement., an effective herbal anti-dandruff shampoo that may be commercially available instead of an existing synthetic shampoo is possible.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86490258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00022
Ganesh G. Dhakad, Rohit V. Chavan, Paresh A. Patil
Chemotherapy is an important part of treatment for patients with gastric cancer. Although there is no single globally accepted standard of care for patients with advanced disease, regimens typically include a fluoropyrimidine and a platinum compound with or without a third drug (usually epirubicin or docetaxel). Oral fluoropyrimidines, such as capecitabine, offer clear advantages to patients in terms of convenience, but it is only recently that comprehensive data on their efficacy and safety in patients with gastric cancer have become available. The present article reviews capecitabine in the treatment of advanced and resectable gastric cancer. Ongoing Phase III trials involving capecitabine are also discussed. The data show that capecitabine is now established as an integral part of the multi-agent regimens used in the management of patients with gastric cancers.
{"title":"Review on Theoretical Study of Capacitabine use in Colon Cancer","authors":"Ganesh G. Dhakad, Rohit V. Chavan, Paresh A. Patil","doi":"10.52711/2321-5836.2022.00022","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00022","url":null,"abstract":"Chemotherapy is an important part of treatment for patients with gastric cancer. Although there is no single globally accepted standard of care for patients with advanced disease, regimens typically include a fluoropyrimidine and a platinum compound with or without a third drug (usually epirubicin or docetaxel). Oral fluoropyrimidines, such as capecitabine, offer clear advantages to patients in terms of convenience, but it is only recently that comprehensive data on their efficacy and safety in patients with gastric cancer have become available. The present article reviews capecitabine in the treatment of advanced and resectable gastric cancer. Ongoing Phase III trials involving capecitabine are also discussed. The data show that capecitabine is now established as an integral part of the multi-agent regimens used in the management of patients with gastric cancers.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74070579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00017
Pratik C. Shirsath, Sangita P. Shirsath, Neha R. Jaiswal
Piper betel Linn is commonly known as Betel leaf or pan is an important species of the Piperaceae family, is an evergreen and perennial creeper, with glossy heart-shaped leaves that are magnificent reservoirs of phenol compounds with ant proliferative, ant mutagenic, antibacterial and antioxidant properties. Piper betel Linn has been an important medicinal agent in the various traditional and folk systems of medicine in Southeast Asia countries. Piper betel leaves being largely consumed as a masticator and mouth freshener. It is valued as a mild stimulant and also has its use in Ayurvadic medicine. Phytochemicals studies show that Piper betle contains a wide variety of biologically active compounds whose concentration depends on the variety of the plant species. Many research studies on Piper betel has reported that it contains important chemical constituents such as Chavibetol, Chavibetol acetate, Caryophyllene, Allylpyrocatechol Diacetate, Camphene, Chavibetol methyl ether, Eugenol, a-Pinene, f- Pinene, u-Limonene, Saprobe, 1-8-cineol and Allylpyrocatechol mono acetate. These components are valued as a stimulant for its medicinal properties like anti platelet, anti-inflammatory effects as well as immune modulator, gastro protective and antidiabetic activity. This review is focused on emphasizing the varied pharmacological properties of Piper betel Linn. And its future prospects for improved usage in treating numerous conditions. Current study focuses on evaluating antioxidant and antimicrobial potential of betel leaf. Antioxidant and antimicrobial potential study will help to build a database and promote the utilization of betel leaf as a medicinal herb.
{"title":"Pharmacological activity of Golden heart of The Nature: Piper betel","authors":"Pratik C. Shirsath, Sangita P. Shirsath, Neha R. Jaiswal","doi":"10.52711/2321-5836.2022.00017","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00017","url":null,"abstract":"Piper betel Linn is commonly known as Betel leaf or pan is an important species of the Piperaceae family, is an evergreen and perennial creeper, with glossy heart-shaped leaves that are magnificent reservoirs of phenol compounds with ant proliferative, ant mutagenic, antibacterial and antioxidant properties. Piper betel Linn has been an important medicinal agent in the various traditional and folk systems of medicine in Southeast Asia countries. Piper betel leaves being largely consumed as a masticator and mouth freshener. It is valued as a mild stimulant and also has its use in Ayurvadic medicine. Phytochemicals studies show that Piper betle contains a wide variety of biologically active compounds whose concentration depends on the variety of the plant species. Many research studies on Piper betel has reported that it contains important chemical constituents such as Chavibetol, Chavibetol acetate, Caryophyllene, Allylpyrocatechol Diacetate, Camphene, Chavibetol methyl ether, Eugenol, a-Pinene, f- Pinene, u-Limonene, Saprobe, 1-8-cineol and Allylpyrocatechol mono acetate. These components are valued as a stimulant for its medicinal properties like anti platelet, anti-inflammatory effects as well as immune modulator, gastro protective and antidiabetic activity. This review is focused on emphasizing the varied pharmacological properties of Piper betel Linn. And its future prospects for improved usage in treating numerous conditions. Current study focuses on evaluating antioxidant and antimicrobial potential of betel leaf. Antioxidant and antimicrobial potential study will help to build a database and promote the utilization of betel leaf as a medicinal herb.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"204 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77685526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00021
Rupak K. Swain, Jnyana R. Panda, Rajaram Das, Satyajeet Behera, Sujit K. Patro
Clinical research is the study design intended to check the safety and efficacy of drugs through the important phases, generally conducted in human volunteers to provide safe medications that contribute to well being of humanity. Generally a effective clinical trial study follows certain guidelines issued by ICH-GCP policies. These guidelines and policies are designed for protecting the interest of subjects and obtaining valuable information about the drug in clinical trial. Many research designs are implemented to obtain scientific information about the research study since it is tedious and expensive.
{"title":"Recent Trends in Clinical Trials: An Overview","authors":"Rupak K. Swain, Jnyana R. Panda, Rajaram Das, Satyajeet Behera, Sujit K. Patro","doi":"10.52711/2321-5836.2022.00021","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00021","url":null,"abstract":"Clinical research is the study design intended to check the safety and efficacy of drugs through the important phases, generally conducted in human volunteers to provide safe medications that contribute to well being of humanity. Generally a effective clinical trial study follows certain guidelines issued by ICH-GCP policies. These guidelines and policies are designed for protecting the interest of subjects and obtaining valuable information about the drug in clinical trial. Many research designs are implemented to obtain scientific information about the research study since it is tedious and expensive.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85599554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. vulgaris Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers, sores, inflammation, dyspepsia, healing of wounds, etc. The present study aimed at the evaluation of anti-pyretic activity of the hydroalcoholic extracts of the leaves by in vivo methods. Phytochemical screening reveals the presences of Alkaloids, Saponins, Carbohydrates, Flavonoids and Phenols. The total phenolic content was found 0.691mg/100mg of dry weight of extract, expressed as gallic acid equivalents and the total flavonoid content was found 0.847mg/100mg, expressed as Quercetin equivalents. Antioxidant activity was performed using DPPH method. The IC50 value of Hydroalcoholic extract of Gendarussa vulgaris was found to be 55.79µg/ml. Yeast induced pyrxia and anti-pyretic property of hydroalcoholic extract of leaves of Gendarussa vulgaris. The effect of hydroalcoholic extract of leaves of Gendarussa vulgaris were determined after administration at two dose levels (100 and 200 mg/kg b.w.) in yeast induced pyrxia rats. From the results, it may be concluded that hydroalcoholic extract of leaves of Gendarussa vulgaris possess significant anti-pyretic effect may be due to the effect of antioxidants and constituent present in the leaves.
{"title":"Antipyretic and Anti-oxidant potential of Hydroalcoholic extract of Gendarussa vulgeris","authors":"Mateshwari M. Banwale, Disha Chaouhan, Manjeet Singh, Rajesh Mujariya, Priya Bisen","doi":"10.52711/2321-5836.2022.00010","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00010","url":null,"abstract":"G. vulgaris Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers, sores, inflammation, dyspepsia, healing of wounds, etc. The present study aimed at the evaluation of anti-pyretic activity of the hydroalcoholic extracts of the leaves by in vivo methods. Phytochemical screening reveals the presences of Alkaloids, Saponins, Carbohydrates, Flavonoids and Phenols. The total phenolic content was found 0.691mg/100mg of dry weight of extract, expressed as gallic acid equivalents and the total flavonoid content was found 0.847mg/100mg, expressed as Quercetin equivalents. Antioxidant activity was performed using DPPH method. The IC50 value of Hydroalcoholic extract of Gendarussa vulgaris was found to be 55.79µg/ml. Yeast induced pyrxia and anti-pyretic property of hydroalcoholic extract of leaves of Gendarussa vulgaris. The effect of hydroalcoholic extract of leaves of Gendarussa vulgaris were determined after administration at two dose levels (100 and 200 mg/kg b.w.) in yeast induced pyrxia rats. From the results, it may be concluded that hydroalcoholic extract of leaves of Gendarussa vulgaris possess significant anti-pyretic effect may be due to the effect of antioxidants and constituent present in the leaves.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82177073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00020
Dipak. B. Sonanwane, Anas M. Shah, N. Jaiswal
As per ISO and ASTM standards, nanoparticles are particles of sizes ranging from 1 to 100nm with one or more dimensions. The nanoparticles are generally classified into the organic, inorganic and carbon based particles in nanometric scale that has improved properties compared to larger sizes of respective materials. The nanoparticles show enhanced properties such as high reactivity, strength, surface area, sensitivity, stability, etc. because of their small size. The nanoparticles are synthesised by various methods for research and commercial uses that are classified into three main types namely physical, chemical and mechanical processes that has seen a vast improvement over time. This paper presents a review on nanoparticles, their types, properties, synthesis methods and its applications in the field of environment.
{"title":"Review on Application of Nanoparticles and Classification, Synthesis","authors":"Dipak. B. Sonanwane, Anas M. Shah, N. Jaiswal","doi":"10.52711/2321-5836.2022.00020","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00020","url":null,"abstract":"As per ISO and ASTM standards, nanoparticles are particles of sizes ranging from 1 to 100nm with one or more dimensions. The nanoparticles are generally classified into the organic, inorganic and carbon based particles in nanometric scale that has improved properties compared to larger sizes of respective materials. The nanoparticles show enhanced properties such as high reactivity, strength, surface area, sensitivity, stability, etc. because of their small size. The nanoparticles are synthesised by various methods for research and commercial uses that are classified into three main types namely physical, chemical and mechanical processes that has seen a vast improvement over time. This paper presents a review on nanoparticles, their types, properties, synthesis methods and its applications in the field of environment.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72953704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00015
Nikhil N Kute, S. D. Mankar, S. Bhawar
Biosimilars are biological products that are the replicas of their innovator biopharmaceuticals. The term “biosimilar” is in common use in the European Union, while the term “follow on biologics” is more popular in the American context. These are developed after patent expiration of innovator biopharmaceuticals and are submitted for separate marketing approval. In view of the structural and manufacturing complexities of biopharmaceuticals, biosimilars should not be considered as “biological generics”. These are rather unique molecules with limited data at time of approval, so there are concerns about the safety and efficacy of biosimilars. The Indian biotechnology industry is also gaining momentum, with revenues of over U.S. $ 2.0 billion in 2006, 70% of which is biopharmaceuticals. These are projected to reach up to $580 million in 2012.This article will address the differences between biosimilars and chemical generics, issues of concern with the use of biosimilars and need of appropriate regulations for their approval.
{"title":"Biosimilar and it’s Current Perspective – A Review","authors":"Nikhil N Kute, S. D. Mankar, S. Bhawar","doi":"10.52711/2321-5836.2022.00015","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00015","url":null,"abstract":"Biosimilars are biological products that are the replicas of their innovator biopharmaceuticals. The term “biosimilar” is in common use in the European Union, while the term “follow on biologics” is more popular in the American context. These are developed after patent expiration of innovator biopharmaceuticals and are submitted for separate marketing approval. In view of the structural and manufacturing complexities of biopharmaceuticals, biosimilars should not be considered as “biological generics”. These are rather unique molecules with limited data at time of approval, so there are concerns about the safety and efficacy of biosimilars. The Indian biotechnology industry is also gaining momentum, with revenues of over U.S. $ 2.0 billion in 2006, 70% of which is biopharmaceuticals. These are projected to reach up to $580 million in 2012.This article will address the differences between biosimilars and chemical generics, issues of concern with the use of biosimilars and need of appropriate regulations for their approval.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82072604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00012
S. R., Subadradevi J., Saranya Shanmuga Priya, R. Raja
Introduction: The prevalence of anaemia is high in developing countries due to poor economic, malnutrition, heredity diseases and pregnancy and reduced health care utilization. Increased Iron requirement and mal absorption of Iron also cause the Anaemia in chronic blood loss during menstrual periods. Methodology: A randomised, cross sectional study was conducted for 6 months Based on inclusion and exclusion criteria.120 anaemic patients were screened for biochemical tests. Results: Out of 120 patients, 32% were male and 68% were female. Majority of patients fall under the age group of 17 to 30 years. The educational status indicates, 40% were high school and 35% were illiterate. Majority of the patients were ideal body weight in 38% and 34% were under over weight. The severity was analysed based on Hb value and found that, 8% patient were severe, 8% were moderate and 88% were in mild anaemia. The mean Hb value was found that 10.82 mg/dl. Only 40% of patients are taking the daily breakfast regularly and 42% of female patients not consuming red meat, fish and chicken. Serum ferritin value is only 5.8 ng/ml, MCV found that 72.30 fL and Hb is 10.82 g/dl. Conclusion: The health education on healthy diet and creating awareness on risk factors of anaemia helps to avaoid the severity and complications of anaemia. The effective Pharmaceutical care services on anaemic patients are essential to prevent the morbidity and mortality rate.
{"title":"A Study on Prevalence and Risk Factors of Anaemia among patients at Tertiary Care Hospital","authors":"S. R., Subadradevi J., Saranya Shanmuga Priya, R. Raja","doi":"10.52711/2321-5836.2022.00012","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00012","url":null,"abstract":"Introduction: The prevalence of anaemia is high in developing countries due to poor economic, malnutrition, heredity diseases and pregnancy and reduced health care utilization. Increased Iron requirement and mal absorption of Iron also cause the Anaemia in chronic blood loss during menstrual periods. Methodology: A randomised, cross sectional study was conducted for 6 months Based on inclusion and exclusion criteria.120 anaemic patients were screened for biochemical tests. Results: Out of 120 patients, 32% were male and 68% were female. Majority of patients fall under the age group of 17 to 30 years. The educational status indicates, 40% were high school and 35% were illiterate. Majority of the patients were ideal body weight in 38% and 34% were under over weight. The severity was analysed based on Hb value and found that, 8% patient were severe, 8% were moderate and 88% were in mild anaemia. The mean Hb value was found that 10.82 mg/dl. Only 40% of patients are taking the daily breakfast regularly and 42% of female patients not consuming red meat, fish and chicken. Serum ferritin value is only 5.8 ng/ml, MCV found that 72.30 fL and Hb is 10.82 g/dl. Conclusion: The health education on healthy diet and creating awareness on risk factors of anaemia helps to avaoid the severity and complications of anaemia. The effective Pharmaceutical care services on anaemic patients are essential to prevent the morbidity and mortality rate.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82412375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.52711/2321-5836.2022.00011
Meenakshi P, Soumya Mohanan T V, Anjali S
There is a new public health crisis threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV). Covid 19 is transmitted by inhalation or contact with infected droplets. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some (usually the elderly and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi organ dysfunction. Many people are asymptomatic. Masks act as a simple barrier and help stop respiratory droplets from traveling into the air and onto other people. However, wearing a mask for an extended period can create unwanted side effects, such as mask mouth.
{"title":"Mask mouth: A Novel Threat to Oral cavity","authors":"Meenakshi P, Soumya Mohanan T V, Anjali S","doi":"10.52711/2321-5836.2022.00011","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00011","url":null,"abstract":"There is a new public health crisis threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV). Covid 19 is transmitted by inhalation or contact with infected droplets. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some (usually the elderly and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi organ dysfunction. Many people are asymptomatic. Masks act as a simple barrier and help stop respiratory droplets from traveling into the air and onto other people. However, wearing a mask for an extended period can create unwanted side effects, such as mask mouth.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85342770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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