Background: Despite the improvements that have been made in treatment of breast cancer, upper-limb lymphedema is still an unsolved problem in the treatment of women with breast cancer. Upper extremity lymphedema may accompany with decreased in shoulder range of motion and strength, and also pain. Nowadays, exercise training acts as a treatment method to control lymphedema in breast cancer survivors. Therefore, this study reviews the results of the applied studies in this field to survey the influ-ences of exercise training on lymphedema and to determine its related symptoms in women with breast cancer. Data Sources: Literature investigation was conducted on August 1st, 2016 using PUBMED, MEDLINE, CINAHL, and Google Scholar databases. StudySelection: RandomizedandnonrandomizedcontrolledtrialspublishedinEnglishwereincluded. Twelvetrailsmetinclusion criteria. DataExtraction: Datawereextractedinastandardizedmannerintothepredefinedtable. Then,qualityof thestudieswasevaluated using the guide to community preventive services tool. Conclusions: It can be seen that a few studies have examined the effect of exercise training on lymphedema to conduct a review study. So, lymphedema continues to be a problem for breast cancer survivors. According to most studies, aerobic, resistance and stretching training programs had no influence on the volume and circumference of arm in lymphedema cancer patients, but the training had a noticeable influence on quality of life
{"title":"Exercise Training and Breast Cancer-Related Lymphedema: A Systematic Review","authors":"S. Naghibi, Fatemeh Tabrizi","doi":"10.5812/RIJM.11967","DOIUrl":"https://doi.org/10.5812/RIJM.11967","url":null,"abstract":"Background: Despite the improvements that have been made in treatment of breast cancer, upper-limb lymphedema is still an unsolved problem in the treatment of women with breast cancer. Upper extremity lymphedema may accompany with decreased in shoulder range of motion and strength, and also pain. Nowadays, exercise training acts as a treatment method to control lymphedema in breast cancer survivors. Therefore, this study reviews the results of the applied studies in this field to survey the influ-ences of exercise training on lymphedema and to determine its related symptoms in women with breast cancer. Data Sources: Literature investigation was conducted on August 1st, 2016 using PUBMED, MEDLINE, CINAHL, and Google Scholar databases. StudySelection: RandomizedandnonrandomizedcontrolledtrialspublishedinEnglishwereincluded. Twelvetrailsmetinclusion criteria. DataExtraction: Datawereextractedinastandardizedmannerintothepredefinedtable. Then,qualityof thestudieswasevaluated using the guide to community preventive services tool. Conclusions: It can be seen that a few studies have examined the effect of exercise training on lymphedema to conduct a review study. So, lymphedema continues to be a problem for breast cancer survivors. According to most studies, aerobic, resistance and stretching training programs had no influence on the volume and circumference of arm in lymphedema cancer patients, but the training had a noticeable influence on quality of life","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47818816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Betrayal in marriage is a moving issue for couples and families. Objectives: Thepresentstudyaimedtoexaminetheeffectivenessof grouprealitytherapyinruminationandself-esteemof women with the experience of betrayal from their husbands. Methods: Research method was semi-experimental with a pre-test post-test design. The statistical population of the research consisted of women who had visited consultation centers in Tehran and had requested for consultation services. Using a convenience non-randomsamplingmethod,30individualswereselectedanddividedintotwogroups: experimentalgroup(15individuals)and controlgroup(15individuals). DatacollectionwasdonebasedontheruminationquestionnairedesignedbyNolanHoksmaaswell as Maro and Rozenberg’s self-esteem questionnaire. Results: Findings showed the average of rumination in women with the experience of betrayal from their husbands has changed, leading to a decrease in rumination. Moreover, teaching reality therapy helps increase in women’s self-esteem (P < 0.05). Conclusion: Basedonthefindingsofthisresearch,itcanbeconcludedthatgrouprealitytherapyhasapositiveeffectonrumination and self-esteem in women with the experience of betrayal.
{"title":"Effectiveness of Group Reality Therapy in Rumination and Self-Esteem of Women with Experience of Betrayal from Their Husbands","authors":"E. Firozi, Parivash Vakili","doi":"10.5812/RIJM.57243","DOIUrl":"https://doi.org/10.5812/RIJM.57243","url":null,"abstract":"Background: Betrayal in marriage is a moving issue for couples and families. Objectives: Thepresentstudyaimedtoexaminetheeffectivenessof grouprealitytherapyinruminationandself-esteemof women with the experience of betrayal from their husbands. Methods: Research method was semi-experimental with a pre-test post-test design. The statistical population of the research consisted of women who had visited consultation centers in Tehran and had requested for consultation services. Using a convenience non-randomsamplingmethod,30individualswereselectedanddividedintotwogroups: experimentalgroup(15individuals)and controlgroup(15individuals). DatacollectionwasdonebasedontheruminationquestionnairedesignedbyNolanHoksmaaswell as Maro and Rozenberg’s self-esteem questionnaire. Results: Findings showed the average of rumination in women with the experience of betrayal from their husbands has changed, leading to a decrease in rumination. Moreover, teaching reality therapy helps increase in women’s self-esteem (P < 0.05). Conclusion: Basedonthefindingsofthisresearch,itcanbeconcludedthatgrouprealitytherapyhasapositiveeffectonrumination and self-esteem in women with the experience of betrayal.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43926568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Acomprehensiveandvalidassessmentsystemalongwithcontinuousassessingof thissystemarerequiredtoassign actual score to the faculty members’ educational performance which is essential for any planning to improve the quality of teaching. Thisstudyaimstodeterminethetrendinoutcomesof assessingthefacultymembersof Schoolof MedicineinMashhadduring a three- year period. Methods: The present descriptive study aims to evaluate the trend in assessment score changes of the faculty members of School of Medicine in six academic semesters. The population under study was all the faculty members of school of medicine in Mashhad, who were selected based on the census. The questionnaire on the survey system was used to collect data. Descriptive indicator and repeated measures ANOVA were used for frequent assessments. The data were analyzed by SPSS software (ver.11.5). Results: Mean and standard deviation of the faculty members’ assessment scores in each academic semester were reported as fol-lows: the first semester of 92 (83.66 ± 6.15), the second semester of 92 (84.45 ± 5.92), the first semester of 93 (84.84 ± 6.03), the second semester of 93 (84.47 ± 6.65), the first semester of 94 (85.79 ± 5.67), the second semester of 94 (85.49 ± 5.05). The results showed there was no significant difference between the faculty members’ assessment scores and their academic ranking, sex, promotion as well as lack of promotion during the years 1392 - 1394. Meanwhile, it was revealed Doctor of Medicine degree or lack of it did not have any influence on rate of changes in assessment scores. Conclusions: Attempts to empower the faculty members in terms of education and teaching skills as well as apply appropriate tools and methods of assessment may relieve the monotony of assessment scores.
{"title":"Evaluating the Trend in Assessment Score of the Faculty Members at Basic Sciences Courses, School of Medicine, Mashhad, (1392 - 1394 Hejri Shamsi, 2013 - 2015)","authors":"A. Heidari, Maliheh Dadgar Moghaddam","doi":"10.5812/RIJM.12520","DOIUrl":"https://doi.org/10.5812/RIJM.12520","url":null,"abstract":"Background: Acomprehensiveandvalidassessmentsystemalongwithcontinuousassessingof thissystemarerequiredtoassign actual score to the faculty members’ educational performance which is essential for any planning to improve the quality of teaching. Thisstudyaimstodeterminethetrendinoutcomesof assessingthefacultymembersof Schoolof MedicineinMashhadduring a three- year period. Methods: The present descriptive study aims to evaluate the trend in assessment score changes of the faculty members of School of Medicine in six academic semesters. The population under study was all the faculty members of school of medicine in Mashhad, who were selected based on the census. The questionnaire on the survey system was used to collect data. Descriptive indicator and repeated measures ANOVA were used for frequent assessments. The data were analyzed by SPSS software (ver.11.5). Results: Mean and standard deviation of the faculty members’ assessment scores in each academic semester were reported as fol-lows: the first semester of 92 (83.66 ± 6.15), the second semester of 92 (84.45 ± 5.92), the first semester of 93 (84.84 ± 6.03), the second semester of 93 (84.47 ± 6.65), the first semester of 94 (85.79 ± 5.67), the second semester of 94 (85.49 ± 5.05). The results showed there was no significant difference between the faculty members’ assessment scores and their academic ranking, sex, promotion as well as lack of promotion during the years 1392 - 1394. Meanwhile, it was revealed Doctor of Medicine degree or lack of it did not have any influence on rate of changes in assessment scores. Conclusions: Attempts to empower the faculty members in terms of education and teaching skills as well as apply appropriate tools and methods of assessment may relieve the monotony of assessment scores.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46783213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maziar Nafisi, Mohamd Reza Guity, Nima Bagheri, Saeed Khabiri
Introduction: Despite the obvious advantages of arthroscopic rotator cuff repair, there are no definitive evidences regarding the superiority of this method over opensurgery. The aim of this study is tocompare the resultsof arthroscopic rotatorcuff repair and open repair surgery. Methods: A total of 52 patients referring to a general university hospital were included in the study and assigned to two groups of arthroscopic repair and open repair. Demographic information of patients and the presence of any underlying disease and the grade of rotator cuff tear were recorded. The pain scores of the patients were measured three times, before, 48 h after surgery and 6-monthfollow-up,usingtheVASsystem. Toevaluatetheclinicalperformanceof patients,UCLAscoringsystem(only6monthsafter the surgery) and Constant (before and 6 months after surgery) were utilized. Results: 32 patients were assigned to the open repair surgery and 20 to the arthroscopic repair group. The two groups were not significantly different in terms of pain variables, 48 hours after operation (P = 0.054) and 6 months after operation (P = 0.638), constant score 6 months after operation (P = 0.157) and UCLA shoulder rating scale 6 months after surgery (P = 0.167). Moreover, there was not any significant difference between the two groups with regard to these variables before surgery. Conclusions: The results of this study showed that arthroscopic rotator cuff repair was a safe procedure which was as effective as openrepairsurgery. Also,reducedpostoperativepainwasoneof theadvantagesof thismethodnotedinthepresentstudy,although the long-term severity of pain in this method was not significantly different from the pain of patients undergoing open surgery.
{"title":"A Comparative Study on the Clinical Results of Arthroscopic Rotator Cuff Repair and Open Repair Surgery","authors":"Maziar Nafisi, Mohamd Reza Guity, Nima Bagheri, Saeed Khabiri","doi":"10.5812/rijm.60817","DOIUrl":"https://doi.org/10.5812/rijm.60817","url":null,"abstract":"Introduction: Despite the obvious advantages of arthroscopic rotator cuff repair, there are no definitive evidences regarding the superiority of this method over opensurgery. The aim of this study is tocompare the resultsof arthroscopic rotatorcuff repair and open repair surgery. Methods: A total of 52 patients referring to a general university hospital were included in the study and assigned to two groups of arthroscopic repair and open repair. Demographic information of patients and the presence of any underlying disease and the grade of rotator cuff tear were recorded. The pain scores of the patients were measured three times, before, 48 h after surgery and 6-monthfollow-up,usingtheVASsystem. Toevaluatetheclinicalperformanceof patients,UCLAscoringsystem(only6monthsafter the surgery) and Constant (before and 6 months after surgery) were utilized. Results: 32 patients were assigned to the open repair surgery and 20 to the arthroscopic repair group. The two groups were not significantly different in terms of pain variables, 48 hours after operation (P = 0.054) and 6 months after operation (P = 0.638), constant score 6 months after operation (P = 0.157) and UCLA shoulder rating scale 6 months after surgery (P = 0.167). Moreover, there was not any significant difference between the two groups with regard to these variables before surgery. Conclusions: The results of this study showed that arthroscopic rotator cuff repair was a safe procedure which was as effective as openrepairsurgery. Also,reducedpostoperativepainwasoneof theadvantagesof thismethodnotedinthepresentstudy,although the long-term severity of pain in this method was not significantly different from the pain of patients undergoing open surgery.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43642257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Jabini, Elahe Skandari, K. Ghaffarzadegan, M. Farzanehfar
Introduction: Pancreatic hydatid cyst (PHC), a rare parasitic infectious disease, is caused by the larvae of Echinococus granulosus. Commonhumanorgansaffectedbythehydatidcystaretheliverandlunge,butitrarelyinvolvesotherorganssuchasthepancreas. Case Presentation: A rare case is reported of a patient with a pancreatic head hydatid cyst. The result of the patient’s preliminary serologicalsurveyswasnegativeandthepancreaticlesionwassuspectedtobeapseudocystorcysticpancreaticneoplasms. Follow-ing complete excision of the lesion, the pathological analysis of the surgical specimen confirmed hydatid disease. Conclusions: Pancreatic hydatid cysts may be confused with more common lesions of the pancreas such as pseudocysts and cystic pancreatic neoplasms. Physicians should always consider this disease in the differential diagnosis, especially for patients from endemic areas.
{"title":"Pancreatic Head Hydatid Cyst: An Unusual Case","authors":"R. Jabini, Elahe Skandari, K. Ghaffarzadegan, M. Farzanehfar","doi":"10.5812/RIJM.13828","DOIUrl":"https://doi.org/10.5812/RIJM.13828","url":null,"abstract":"Introduction: Pancreatic hydatid cyst (PHC), a rare parasitic infectious disease, is caused by the larvae of Echinococus granulosus. Commonhumanorgansaffectedbythehydatidcystaretheliverandlunge,butitrarelyinvolvesotherorganssuchasthepancreas. Case Presentation: A rare case is reported of a patient with a pancreatic head hydatid cyst. The result of the patient’s preliminary serologicalsurveyswasnegativeandthepancreaticlesionwassuspectedtobeapseudocystorcysticpancreaticneoplasms. Follow-ing complete excision of the lesion, the pathological analysis of the surgical specimen confirmed hydatid disease. Conclusions: Pancreatic hydatid cysts may be confused with more common lesions of the pancreas such as pseudocysts and cystic pancreatic neoplasms. Physicians should always consider this disease in the differential diagnosis, especially for patients from endemic areas.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43439349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bidar, S. Nabavi, M. Shakeri, Mona Zamanpour, H. Jafarzadeh
Background: The aim of this study was to compare the apical sealing ability of cold lateral condensation and Obtura II by using fluid filtration method. Methods: Thirty four single-canal mandibular premolars with mature apices and apical curvature less than 20 degrees were selected. For obtaining complete similarity among samples, all teeth were shortened to 15 mm by cutting the remained crown. For canal preparation, the manual step-back technique by K-files was used. The teeth were divided into two experimental groups (each group included 15 teeth), positive controls (n = 2), and negative controls (n = 2). Teeth in group 1 and 2 were obturated with cold lateral condensation and Obtura II, respectively. To allow the sealer to set, all teeth were stored at 100% humidity and 37°C for the next seven days. For measurement of apical leakage, fluid filtration method was used. The amount of leakage in each canal was recorded as µ L/min/cm H 2 O. Independent T-test was used for statistical analysis. Results: Teeth obturated with cold lateral condensation showed significantly more leakage than those obturated with Obtura II (P value = 0.022). Conclusions: Obtura II may obtain better apical seal than cold lateral condensation.
{"title":"The Comparison of Apical Leakage between Two Obturation Techniques (Cold Lateral Condensation and Obtura II) by Using Fluid Filtration Method","authors":"M. Bidar, S. Nabavi, M. Shakeri, Mona Zamanpour, H. Jafarzadeh","doi":"10.5812/RIJM.57759","DOIUrl":"https://doi.org/10.5812/RIJM.57759","url":null,"abstract":"Background: The aim of this study was to compare the apical sealing ability of cold lateral condensation and Obtura II by using fluid filtration method. Methods: Thirty four single-canal mandibular premolars with mature apices and apical curvature less than 20 degrees were selected. For obtaining complete similarity among samples, all teeth were shortened to 15 mm by cutting the remained crown. For canal preparation, the manual step-back technique by K-files was used. The teeth were divided into two experimental groups (each group included 15 teeth), positive controls (n = 2), and negative controls (n = 2). Teeth in group 1 and 2 were obturated with cold lateral condensation and Obtura II, respectively. To allow the sealer to set, all teeth were stored at 100% humidity and 37°C for the next seven days. For measurement of apical leakage, fluid filtration method was used. The amount of leakage in each canal was recorded as µ L/min/cm H 2 O. Independent T-test was used for statistical analysis. Results: Teeth obturated with cold lateral condensation showed significantly more leakage than those obturated with Obtura II (P value = 0.022). Conclusions: Obtura II may obtain better apical seal than cold lateral condensation.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43564385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: To deal with health problems, using an approach, based on prevention perspective, consist of different types of prevention, can be a proper way to manage the health problems such as surgical site infections (SSIs). Objective: Introducing an action plan from the perspective of “prevention” for dealing with surgical site infections (SSIs). Evidence Acquisition: We have used 5 known prevention levels as a simple approach for dealing with surgical site infections. For gathering information, electronic databases, including Scopus, Medline, ISI, IranMedex, and Irandoc sites were used. Results: For prevention of surgical site infection, a comprehensive evidence based instruction, consist of 75 related factors and 74 proposed measurable and operational preventive activities was developed. Conclusions: Weconcludedthat,todealwithsurgicalsiteinfectionsuseof theproposedactionplanmaybeuseful. Evenwebelieve that, this approach can be used to deal with any health problems including diseases, disorders, accidents and events.
{"title":"Comprehensive Preventive Approach to Surgical Site Infections (SSIs): A Review","authors":"S. Razavi, L. Seddigh, F. Khatami","doi":"10.5812/RIJM.14047","DOIUrl":"https://doi.org/10.5812/RIJM.14047","url":null,"abstract":"Background: To deal with health problems, using an approach, based on prevention perspective, consist of different types of prevention, can be a proper way to manage the health problems such as surgical site infections (SSIs). Objective: Introducing an action plan from the perspective of “prevention” for dealing with surgical site infections (SSIs). Evidence Acquisition: We have used 5 known prevention levels as a simple approach for dealing with surgical site infections. For gathering information, electronic databases, including Scopus, Medline, ISI, IranMedex, and Irandoc sites were used. Results: For prevention of surgical site infection, a comprehensive evidence based instruction, consist of 75 related factors and 74 proposed measurable and operational preventive activities was developed. Conclusions: Weconcludedthat,todealwithsurgicalsiteinfectionsuseof theproposedactionplanmaybeuseful. Evenwebelieve that, this approach can be used to deal with any health problems including diseases, disorders, accidents and events.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46079508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seyed Mohsen Seyednozadi, Mercede Shahraki, M. Dadgarmoghaddam
Professor of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Assistant Professor of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Corresponding author: Maliheh Dadgarmoghaddam, Assistant Professor of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. E-mail: maliheh_dadgar@yahoo.com Received 2017 June 10; Accepted 2017 November 13.
{"title":"The Scope of Community Medicine","authors":"Seyed Mohsen Seyednozadi, Mercede Shahraki, M. Dadgarmoghaddam","doi":"10.5812/RIJM.55620","DOIUrl":"https://doi.org/10.5812/RIJM.55620","url":null,"abstract":"Professor of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Assistant Professor of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Corresponding author: Maliheh Dadgarmoghaddam, Assistant Professor of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. E-mail: maliheh_dadgar@yahoo.com Received 2017 June 10; Accepted 2017 November 13.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47327108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Vosoughinia, M. Latifnia, M. Abdizadeh, E. Amirmajdi, M. Ahadi
Abstract Background: Inflammatory bowel disease is a disorder with unknown origin in which environment, genetics, and immunity play a part. Although colonoscopy and biopsy are expensive and invasive, are used to monitoring the mucosal inflammation. Fecal calprotectin is a non-invasive test which has attracted a lot of attention. We aimed to determine the relation of fecal calprotectin and clinical activity of ulcerative colitis. Methods: This cross-sectional study took place with the confirmation of ethics committee of Mashhad University of Medical Sci- ences in 2014 - 2015. Patients with diagnosis of ulcerative colitis were included; demographic information was recorded and clinical activity of disease was evaluated. Fecal calprotectin was measured by the quantitative ELISA method and results of laboratory studies and clinical examinations were analyzed by SPSS software version 16. Level of significance was considered less than 0.05. Results: Seventy patients were studied (male = 56%, average age = 38 15). 25 patients (36.2%) were newly diagnosed. The average period of disease was 4.1 ± 5 years. 25 individuals (35.7%) had mild, 19 individuals (27.1%) had moderate, and 26 individuals (37.1%) had severe disease. Averages of fecal calprotectin in mild, moderate, and severe disease were 132 111, 119 44 and 141 78 g/ g, respectively. Averages of fecal calprotectin in mild and moderate disease (P = 0.874), in mild and severe (P = 0.925) and in moderate and severe disease (P = 0.662) were not significantly different. Conclusions: Although fecal calprotectin in severe ulcerative colitis is higher, it has no relation with disease clinical activity.
{"title":"The Relation Between Fecal Calprotectin and the Rate of Clinical Activity of Ulcerative Colitis","authors":"H. Vosoughinia, M. Latifnia, M. Abdizadeh, E. Amirmajdi, M. Ahadi","doi":"10.5812/RIJM.14533","DOIUrl":"https://doi.org/10.5812/RIJM.14533","url":null,"abstract":"Abstract Background: Inflammatory bowel disease is a disorder with unknown origin in which environment, genetics, and immunity play a part. Although colonoscopy and biopsy are expensive and invasive, are used to monitoring the mucosal inflammation. Fecal calprotectin is a non-invasive test which has attracted a lot of attention. We aimed to determine the relation of fecal calprotectin and clinical activity of ulcerative colitis. Methods: This cross-sectional study took place with the confirmation of ethics committee of Mashhad University of Medical Sci- ences in 2014 - 2015. Patients with diagnosis of ulcerative colitis were included; demographic information was recorded and clinical activity of disease was evaluated. Fecal calprotectin was measured by the quantitative ELISA method and results of laboratory studies and clinical examinations were analyzed by SPSS software version 16. Level of significance was considered less than 0.05. Results: Seventy patients were studied (male = 56%, average age = 38 \u0006 15). 25 patients (36.2%) were newly diagnosed. The average period of disease was 4.1 ± 5 years. 25 individuals (35.7%) had mild, 19 individuals (27.1%) had moderate, and 26 individuals (37.1%) had severe disease. Averages of fecal calprotectin in mild, moderate, and severe disease were 132 \u0006 111, 119 \u0006 44 and 141 \u0006 78 \u0016g/ g, respectively. Averages of fecal calprotectin in mild and moderate disease (P = 0.874), in mild and severe (P = 0.925) and in moderate and severe disease (P = 0.662) were not significantly different. Conclusions: Although fecal calprotectin in severe ulcerative colitis is higher, it has no relation with disease clinical activity.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71295429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Bahadorkhan, M. Abouei, Omid Daneshvarfard, M. Arjmand
Objectives: In this control trial study we showed the neuroprotective effects of the erythropoietin (EPO) in traumatic brain injury in animal model. Methods: The research was carried out on 50 male Wistar rats weighing 200 to 250 g. They were divided into two groups of control and case. The rats were anesthetized, right frontal craniotomy was performed and then the brain damage was caused by weight-drop model. In the case group, after 3 hours and again after 24 hours of craniotomy and creation of brain lesions in the right hemisphere, 500 u/kg erythropoietin was injected into peritoneum but in the control group, the rats did not receive any drug. Then the behavior, motor function and balance on the second day and the fourteenth day after injection of erythropoietin were evaluated. After that, the rats were killed and the brain tissues sent to the laboratory for pathological assessment of brain tissues. Results: The average of cross-sectional damage in the case group that received erythropoietin drug was reported 22.55% and in the control group 37.41%, and the motor balance function after fourteenth day in the group that received erythropoietin was 69.12% and better in comparison with the control group (46.27%) that did not receive any drug. Conclusions: erythropoietin has a protective effect on neurons and improves the sub-acute changes in head after brain injury and increases the motor balance abilities in rats.
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