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Effectiveness of Acceptance and Commitment Therapy in Sleep Quality, Resil- ience, and Death Anxiety in the Elderly 接受与承诺疗法对老年人睡眠质量、抵抗力和死亡焦虑的影响
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.254167.1021
Bahman Hajatnia, Buick Tajeri, K. H. Alizadeh
Background: Aging currently has a major share of population composition. The aim of this study was to determine the effectiveness of acceptance and commitment therapy (ACT) on sleep quality, resilience, and death anxiety of the elderly. Methods: The research method was pre-test, post-test with two-month follow-up period with control group. The statistical population of this study included all elderly residents in nursing homes in Shiraz in 2019. The sample consisted of 30 people from the mentioned population who were selected by convenience sampling method and assigned to two groups of acceptance and commitment therapy (n=15), and control group (n=15) using simple randomization method. Data were collected using a resilience questionnaire (Conner-Davidson, 2003), Death Anxiety Scale (Collette-Lester, 1969), and Pittsburgh Sleep Quality Questionnaire. Data were analyzed using the repeated measure ANOVA, and the above statistical analysis was performed using SPSS.22 software. Results: The results showed that acceptance and commitment therapy was effective on improving sleep quality (p <0.001) and resilience (p <0.001) and death anxiety (p <0.001) in elderly people. Conclusion: It can be concluded that acceptance and commitment therapy was effective on improving sleep quality and resilience and death anxiety in elderly people.
背景:老龄化目前在人口构成中占很大比重。本研究旨在探讨接受与承诺疗法(ACT)对老年人睡眠质量、恢复力和死亡焦虑的影响。方法:采用前测、后测与对照组随访2个月的研究方法。本研究的统计人口包括设拉子2019年养老院的所有老年人。本研究采用方便抽样法从上述人群中抽取30人,采用简单随机法分为接受与承诺治疗组(n=15)和对照组(n=15)。数据收集采用弹性问卷(Conner-Davidson, 2003)、死亡焦虑量表(Collette-Lester, 1969)和匹兹堡睡眠质量问卷。数据分析采用重复测量方差分析,以上统计分析采用SPSS.22软件进行。结果:接受承诺疗法对改善老年人睡眠质量(p <0.001)、恢复力(p <0.001)和死亡焦虑(p <0.001)有显著效果。结论:接受承诺疗法对改善老年人睡眠质量、恢复力和死亡焦虑有较好的效果。
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引用次数: 1
Effectiveness of Emotion-focused Therapy-based Enrichment Program on Psychological Well-being, Marital Relationship Quality and Marital Satisfaction in Mothers of Children with Specific Learning Disabilities 以情绪为中心的强化治疗对特殊学习障碍儿童母亲心理健康、婚姻关系质量和婚姻满意度的影响
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.249708.0
E. Deyreh, Sara Asgarian
Background: Present study aimed to investigate effectiveness of couples’ relationships enrichment based on emotion-focused therapy on psychological well-being, and marital quality and satisfaction among mothers of children with specific learning disability. Method: This study was a semi-experimental work with pretest-posttest design and control group. The statistical population included mothers of children with specific learning disability referring to Talash clinic in district 1 of Tehran in 2017-2018. 30 mothers of children with specific learning disability were chosen as samples and randomly were divided into 2 groups (control and experimental). The experimental group was exposed to 8 sessions of couples’ relations enrichment based on emotion-focused therapy. Then, post-test was performed. For data collection, Ryff’s psychological well-being scale, Revised Dyadic Adjustment Scale and marital satisfaction questionnaire were used. Data analysis was conducted using MANCOVA. Results: Statistical data analysis indicates that the enrichment program caused a significant improvement on psychological well-being, and marital quality and satisfaction of experimental group compared to the controls (P
背景:本研究旨在探讨基于情感聚焦疗法的夫妻关系充实对特殊学习障碍儿童母亲心理健康、婚姻质量和满意度的影响。方法:采用前测后测设计和对照组的半实验方法。统计人群包括2017-2018年在德黑兰1区Talash诊所就诊的患有特殊学习障碍儿童的母亲。选取30名特殊学习障碍患儿母亲为样本,随机分为对照组和实验组。实验组接受了8次以情感为中心的夫妻关系强化治疗。然后进行后测。数据收集采用瑞夫心理健康量表、修正二元调整量表和婚姻满意度问卷。采用MANCOVA进行数据分析。结果:统计数据分析表明,与对照组相比,实验组的心理幸福感、婚姻质量和满意度均有显著提高(P
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引用次数: 0
Effectiveness of Schema Therapy in Social Anxiety, Rumination, and Psychological Well-Being among Depressed Patients Referred to Health Centers in Abadan, Iran 图式疗法对转诊至伊朗阿巴丹健康中心的抑郁症患者的社交焦虑、反刍和心理健康的影响
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.254157.1012
Ahmadreza Varmazyar, B. Makvandi, Naser Seraj Khorrami
Background: Depression is a syndrome that includes many symptoms and can have a negative impact on a patient's life. The aim of this study was to investigate the effectiveness of schema therapy on social anxiety, rumination and psychological well-being in depressed patients. Methods: The research method was semi-experimental with pre-test, post-test, follow-up, and control group. The statistical population of this study included all patients with depression referred to Abadan Health Center in 2019. In this study, 30 patients with depression who wished to participate in the study were selected by convenient sampling method from among patients with research centers and were randomly assigned to experimental and control groups (each group consisted of 15 patients). The experimental group underwent schema therapy in 10 sessions of 90 minutes, but the control group did not receive any treatment. Data were collected using the Beck Depression Inventory, Social Anxiety Inventory, Rumination Questionnaire, and Psychological Well-Being Questionnaire. Data analysis was performed by repeated measure analysis of variance using SPSS software version 23. Results: The results showed that schema therapy was effective on rumination (P=0.034), social anxiety (P=0.004), and psychological well-being (P=0.022) in depressed patients. Conclusion: It can be concluded that schema therapy was effective on rumination, social anxiety, and psychological well-being in depressed patients.
背景:抑郁症是一种包括许多症状的综合征,可能对患者的生活产生负面影响。本研究旨在探讨图式疗法对抑郁症患者社交焦虑、反刍和心理健康的影响。方法:采用半实验的研究方法,包括前测、后测、随访和对照组。本研究的统计人群包括2019年阿巴丹健康中心转诊的所有抑郁症患者。本研究采用方便抽样的方法,从各研究中心的患者中选择30名有意愿参与研究的抑郁症患者,随机分为实验组和对照组(每组15名患者)。实验组接受了10次90分钟的图式治疗,而对照组没有接受任何治疗。采用贝克抑郁量表、社交焦虑量表、反刍问卷和心理健康问卷收集数据。数据分析采用SPSS软件23版进行重复测量方差分析。结果:图式疗法对抑郁症患者的反刍(P=0.034)、社交焦虑(P=0.004)和心理健康(P=0.022)均有显著效果。结论:图式疗法对抑郁症患者的反刍、社交焦虑和心理健康有显著的改善作用。
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引用次数: 0
Effectiveness of compassion-focused therapy in alexithymia, adaptive behavior, treatment adherence, and biological factors in patients with type 2 diabetes 同情疗法对2型糖尿病患者述情障碍、适应性行为、治疗依从性和生物学因素的影响
Pub Date : 2021-01-01 DOI: 10.30483/rijm.2021.254196.1048
M. Bahadori, M. Honarmand, P. Asgary, H. Ahadi, L. Moradi
Background and Objective: Diabetic patients experience a plethora of emotional problems in addition to physiological physical problems, which can affect the course of their disease. Therefore, the purpose of the present study was to investigate the effectiveness of compassion-focused therapy (CFT) in alexithymia, adaptive behavior, treatment adherence, and blood sugar of patients with type 2 diabetes. Materials and Methods: In this study, a quasi-experimental design with pretest-posttest and control group was adopted. The study population included the patients with type 2 diabetes in Ahvaz, Iran, in 2020 referring to my center. The sample size (n=30) was selected using convenience sampling, and the participants were randomly and equally assigned to the experimental (CFT) and control groups. To collect study data, the Toronto Alexithymia Scale, Psychosocial Adjustment to Illness Scale, Treatment Adherence Questionnaire, and blood sugar test were used. The CFT group received eight sessions of intervention (each session lasting for 2 h). Multivariate analysis of covariance was used to analyze the data. Results: The obtained results showed that CFT had a significant effect on alexithymia (F=9.27;P=0.006), adaptive behavior (F=6.75;P=0.016), and treatment adherence (F=15.26;P=0.001) of patients with type 2 diabetes in the posttest. There was no significant difference between the experimental and control groups in the blood sugar test (F=0.08;P=0.786). Conclusion: Based on the obtained findings, it can be concluded that CFT is effective in increasing the level of adaptive behavior and treatment adherence.
背景与目的:糖尿病患者除了生理问题外,还存在大量的情绪问题,这些问题会影响其病程。因此,本研究的目的是探讨同情聚焦疗法(CFT)在2型糖尿病患者述情障碍、适应性行为、治疗依从性和血糖方面的有效性。材料与方法:本研究采用前测后测和对照组的准实验设计。研究人群包括2020年到我中心就诊的伊朗阿瓦士2型糖尿病患者。采用方便抽样法选取样本量(n=30),随机平均分为实验组(CFT)和对照组。采用多伦多述情障碍量表、疾病心理社会适应量表、治疗依从性问卷和血糖测试收集研究数据。CFT组接受8次干预(每次干预2小时)。采用多变量协方差分析对数据进行分析。结果:获得的结果显示,CFT对2型糖尿病患者后测述情障碍(F=9.27;P=0.006)、适应行为(F=6.75;P=0.016)和治疗依从性(F=15.26;P=0.001)有显著影响。实验组与对照组血糖值比较,差异无统计学意义(F=0.08;P=0.786)。结论:综上所述,CFT可有效提高患者的适应行为水平和治疗依从性。
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引用次数: 0
Comparison of the effectiveness of acceptance and commitment-based therapy and compassion-focused therapy on the quality of life of mothers with gestational diabetes 以接受和承诺为基础的治疗与以同情为中心的治疗对妊娠期糖尿病母亲生活质量的效果比较
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.254151.1006
Parisa Khoraminejad, J. Khalatbari, M. Seirafi
Introduction: The aim of this study was to compare the effectiveness of acceptance and commitment-based therapy and compassion-focused therapy on the quality of life of mothers with gestational diabetes. Methods: The research method is quasi-experimental with pre-test-post-test-three-group follow-up. The statistical population of the study was all pregnant mothers who referred to Milad Hospital in Tehran in 2019, who were diagnosed with gestational diabetes. In order to form three groups using purposive sampling method (considering the inclusion and exit criteria), 45 patients were selected and then randomly divided into three groups of 15 (acceptance and commitment therapy, compassionate treatment and group Witness) were assigned. Forman and Herbert (2008) acceptance and commitment group training, and Gilbert (2007) self-compassion training were performed for the second experimental group. Also, a three-month follow-up phase was performed on all three groups. The research tool was the quality of life of the World Health Organization (1986). Data analyzed by repeated measure analysis of variance and spss.22. Results: The results showed that acceptance and commitment therapy and compassion-focused therapy had a significant effect on improving the quality of life in mothers with gestational diabetes (p <0.001). Conclusion: As a result, acceptance and commitment therapy has a greater impact on the quality of life of mothers with gestational diabetes than compassion-focused therapy.
前言:本研究的目的是比较接受和承诺为基础的治疗和同情为重点的治疗对妊娠期糖尿病母亲的生活质量的有效性。方法:采用准实验方法,采用前测后测三组随访。该研究的统计人群是2019年转诊到德黑兰米拉德医院的所有孕妇,她们被诊断患有妊娠糖尿病。采用目的抽样法(考虑纳入标准和退出标准),将45例患者随机分为接纳与承诺治疗组、体恤治疗组和群体见证组,每组15人。第二实验组采用Forman and Herbert(2008)的接受与承诺组训练和Gilbert(2007)的自我同情训练。此外,对所有三组进行了为期三个月的随访。研究工具是世界卫生组织的生活质量(1986年)。数据分析采用重复测量方差分析和spss分析。结果:接受承诺治疗和同情治疗对改善妊娠期糖尿病母亲的生活质量有显著作用(p <0.001)。结论:接受与承诺治疗对妊娠期糖尿病母亲生活质量的影响大于同情治疗。
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引用次数: 0
Effect of Glucose-Insulin-Potassium infusion on systolic and diastolic functions in patients with chronic ischemic cardiomyopathy 葡萄糖-胰岛素-钾输注对慢性缺血性心肌病患者收缩和舒张功能的影响
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.254163.1017
B. Bayani, M. Bayani
Background:Ischemic cardiomyopathy is accompanied with some degrees of decreased metabolism.So,a method to facilitate cellular absorption and use of glucose may promote myocardial function and viability .Glucose,Potassium.Insulin solution(GIK) has been used by some successful results in acute ischemic heart disease and decreases the extent of ischemic zone in myocardium and promote ventricular function. Method and Materials: 25 patients with ischemic cardiomyopathy(EF 0.005) but diastolic function of left ventricle were improved significantly after administration of GIK (p 0.005), but because of metabolic improvements and increased in ventricular function after GIK administration, clinical symptoms were decreased. Conclusion:GIK solution administration(As an accessible and cost-effective agent) may improve ventricular diastolic function and clinical symptoms,so we suggest GIK as an effective therapeutic method in ischemic cardiomyopathy.
背景:缺血性心肌病伴有一定程度的代谢降低。因此,一种促进细胞吸收和利用葡萄糖的方法可能会促进心肌功能和活力。胰岛素溶液(Insulin solution, GIK)在急性缺血性心脏病的治疗中有一些成功的结果,它能缩小心肌缺血带的范围,促进心室功能。方法与材料:25例缺血性心肌病患者(EF 0.005)经GIK治疗后左心室舒张功能明显改善(p 0.005),但由于GIK治疗后代谢改善,心室功能增强,临床症状减轻。结论:GIK溶液可改善心室舒张功能,改善临床症状,是一种可获得且经济有效的治疗缺血性心肌病的方法。
{"title":"Effect of Glucose-Insulin-Potassium infusion on systolic and diastolic functions in patients with chronic ischemic cardiomyopathy","authors":"B. Bayani, M. Bayani","doi":"10.30483/RIJM.2021.254163.1017","DOIUrl":"https://doi.org/10.30483/RIJM.2021.254163.1017","url":null,"abstract":"Background:Ischemic cardiomyopathy is accompanied with some degrees of decreased metabolism.So,a method to facilitate cellular absorption and use of glucose may promote myocardial function and viability .Glucose,Potassium.Insulin solution(GIK) has been used by some successful results in acute ischemic heart disease and decreases the extent of ischemic zone in myocardium and promote ventricular function. Method and Materials: 25 patients with ischemic cardiomyopathy(EF 0.005) but diastolic function of left ventricle were improved significantly after administration of GIK (p 0.005), but because of metabolic improvements and increased in ventricular function after GIK administration, clinical symptoms were decreased. Conclusion:GIK solution administration(As an accessible and cost-effective agent) may improve ventricular diastolic function and clinical symptoms,so we suggest GIK as an effective therapeutic method in ischemic cardiomyopathy.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"193 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70076894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effect of Tranexamic Acid and Misoprostol on Blood Loss During and After Cesarean Section: A Randomized Clinical Trial 氨甲环酸与米索前列醇对剖宫产术中和术后出血量的影响:一项随机临床试验
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.249741.0
Seyed Saleh Tabatabaie, A. Alavi, M. Bazaz
Background: One proposed methods to reduce the amount of bleeding during and after cesarean section, is the use of drugs such as Tranexamic acid and Misoprostol.This study aimed to compare the effect of Tranexamicacid and Misoprostol on bloodloss during and after cesarean section. Methods: This is a randomized clinicaltrial performed in Shariati and Khalij-e-Fars Hospitals of Bandar Abbas, Hormozgan, during 2015-2016. The study population included all candidates for cesarean section. 300 pregnant women aged 18-40 years with gestational age of 37-42 weeks were included, divided into three groups each: A received tranexamic acid,B, misoprostol, and C, 200 cc normal saline. During C/S , all patients received 20 and 30 units of oxytocin, respectively. The level of blood loss during the operation was determined by measuring the total blood volume suctioned after removing the placenta and the difference in the weight of bloody sterile pads and surgical sheets before and after the operation. Results: Preoperative hemoglobin level was 11.96±1mg/dl in the groupA,11.62±1.21mg/dl in the groupB, and 12.28±1.26mg/dl in the placebo group, which was statistically significant (P=0.001). Postoperative hemoglobin level was reduced about 1.02±0.35(10.9 ±0.99mg/dl) in the groupA, 1.19±0.52(10.46±1.04mg/dl) in the groupB, and 1.36±0.50(10.93±1.34mg/dl) in the placebo group. There was a significant difference between the three groups in the volume of bloodloss during the operation and the first two hours after the operation(P
背景:一种减少剖宫产术中和术后出血量的方法是使用氨甲环酸和米索前列醇等药物。本研究旨在比较氨甲环酸和米索前列醇对剖宫产术中和术后出血量的影响。方法:这是一项2015-2016年在霍尔木兹干阿巴斯港Shariati和Khalij-e-Fars医院进行的随机临床试验。研究人群包括所有剖宫产手术的候选者。300名年龄在18-40岁,孕周37-42周的孕妇,分为三组:A组给予氨甲环酸,B组给予米索前列醇,C组给予200毫升生理盐水。在C/S期间,所有患者分别接受20和30单位的催产素。术中出血量通过测定取胎盘后吸总血容量及术前术后带血无菌垫、手术片重量差来判断。结果:a组术前血红蛋白水平为11.96±1mg/dl, b组为11.62±1.21mg/dl,安慰剂组为12.28±1.26mg/dl,差异均有统计学意义(P=0.001)。a组术后血红蛋白水平降低1.02±0.35(10.9±0.99mg/dl), b组术后血红蛋白水平降低1.19±0.52(10.46±1.04mg/dl),安慰剂组术后血红蛋白水平降低1.36±0.50(10.93±1.34mg/dl)。三组患者术中出血量及术后2 h出血量比较,差异均有统计学意义(P
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引用次数: 6
Right Coronary Artery to Superior Vena Cava Fistula Following CABG: A Very Rare Case Report 冠脉搭桥后右冠状动脉至上腔静脉瘘1例
Pub Date : 2021-01-01 DOI: 10.30483/RIJM.2021.249751.0
Hamid Hoseinikhah, Mohammad-Hossein Akbari, Kambiz Alizadeh, Kayhan Mizani, Mahsa Moallemi, Omid Javdanfar, Mohammad Ali Roohi Gholkhatmi, Aliasghar Moeinipour
Although most of the Coronary Artery Fistulae to venous system are congenital , we present a case who was treated conservatively and developed an acquired post CABG fistula formation between Right Coronary Artery and Superior Vena Cava that due to with allow-flow shunt and few symptoms. Case presentation We present a 65 year-old man with history of CABG 3 years earlier who present with chest pain. He had developed a 3-vessel diseases well as a recent Myocardial Infarction (MI) with reduced EF (EF= 25%) he presented a Chest Discomfort since 2 month after discharge that increasing by any physical activity. Consultant Cardiologist decided to perform Coronary Angiography to assess the condition of Native Coronary Artery and also Coronary Grafts well. on coronary angiography all of grafts was patents and but there was an abnormal communication between proximal of native Right Coronary Artery and Superior Vena Cava that finally fill the Right Atrium. Conclusion Clinically, although most of Coronary Artery Fistulae are silent and asymptomatic due to Limited amount of shunt, but in some rare cases in which there is a large shunt and steal of coronary circulation, symptoms and signs of Ischemic Heart disease appears that there are surgical and interventional options for closure of this abnormal communications.
虽然大多数冠状动脉静脉系统瘘是先天性的,但我们报告了一个保守治疗的病例,由于允许血流分流和很少的症状,在右冠状动脉和上腔静脉之间形成了获得性冠状动脉搭桥后瘘。病例介绍我们报告一位65岁的男性,3年前有冠脉搭桥病史,目前表现为胸痛。他患有三支血管疾病以及最近的心肌梗死(MI), EF降低(EF= 25%),出院后2个月出现胸部不适,并因任何体育活动而增加。顾问医师决定进行冠状动脉造影以评估原冠状动脉及冠状动脉移植物的状况。冠状动脉造影显示所有移植物均通畅,但原右冠状动脉近端与最终填充右心房的上腔静脉之间的交通异常。结论临床上,虽然大多数冠状动脉瘘因分流量有限而无症状,但在少数有较大分流和冠状动脉循环阻滞的病例中,出现缺血性心脏病的症状和体征,可以选择手术和介入来关闭这种异常的交通。
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引用次数: 0
The Effectiveness of Psychological Education Based on Olson Model on Family Cohesion of Schizophrenic Patients in Bushehr 基于Olson模型的心理教育对布什尔精神分裂症患者家庭凝聚力的影响
Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254159.1014
َAlireza Bibak, N. Amini, E. Deyreh, K. Mirzaei
Background: Family cohesion affects health, mental and physical well-being, academic achievement, and emotional health of the family with disturbance of family environment and feelings of depression, aggressive behaviors and delinquency, and disruption of family members' self-concept. Objectives: This study aimed to investigate the effectiveness of psychological education based on Olson's model on family cohesion of schizophrenic patients in Bushehr. Method: The research method was semi-experimental with a pretest-posttest and follow-up design. The statistical population consisted of 425 patients in all families of schizophrenic patients who were treated in the province's medical centers (both governmental and non-governmental) in Bushehr in 2019. The sample size in this study will be 30 parents of schizophrenic patients. All of them had inclusion criteria and were selected by convenience sampling method and randomly assigned to the experimental and control group. Data obtained by Faces-III Scale (Olson et al., 1983)and analyzed using multivariate analysis of covariance and post-test by Spss.22. Results: The results showed that psychological training based on the Olson model effectively improved family cohesion of schizophrenic patients (p <0.001). Conclusion: Providing psychological services is necessary to promote and cohere the families of schizophrenic patients, so it can be said that psychological training based on family cohesion and flexibility can be used to promote and cohere the families of schizophrenic patients and provide the ground for their psychological care.
背景:家庭凝聚力影响家庭的健康、身心健康、学业成绩和情绪健康,影响家庭环境和抑郁情绪、攻击性行为和犯罪以及家庭成员自我概念的破坏。目的:本研究旨在探讨基于Olson模型的心理教育对布什尔精神分裂症患者家庭凝聚力的有效性。方法:研究方法为半实验性,采用前测后测和随访设计。统计人群包括2019年在布什尔省医疗中心(政府和非政府)接受治疗的所有精神分裂症患者家庭的425名患者。本研究的样本量为30名精神分裂症患者的父母。所有患者都有入选标准,采用方便抽样法进行选择,并随机分为实验组和对照组。通过Faces III量表(Olson等人,1983)获得的数据,并通过Spss.22使用协方差的多变量分析和后验进行分析。结果:基于Olson模型的心理训练有效地提高了精神分裂症患者的家庭凝聚力(p<0.001),可以说,基于家庭凝聚力和灵活性的心理训练可以促进和凝聚精神分裂症患者的家庭,为他们的心理护理提供基础。
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引用次数: 0
A comparative study of interleukin 6 and 17 serum levels in patients undergoing coronary artery bypass surgery using off-pump and on-pump methods 非体外循环和体外循环冠状动脉搭桥术患者血清白细胞介素6和17水平的比较研究
Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254165.1019
Kambiz Alizadeh, A. Hosseinpour, M. Tabari, Majid Rajabian Noghondar, Narges Morovat, A. Izanloo
Introduction: This study aims to investigate the role of coronary artery bypass graft (CABG) surgery by off-pump and on-pump methods in the severity of postoperative inflammation based on serum levels of interleukin 6 (IL6) and interleukin 17 (IL17). Methods: This is a cross-sectional study in which 39 patients’ candidate for CABG were evaluated in terms of serum levels of IL17 and IL6 before and after surgery in two groups of off-pump and on-pump CABG. Results: Thirty-nine patients with an average age of 63±8.9 in the on-pump group and 59±7.74 in the off-pump group were evaluated. There was no significant difference between the two groups in terms of baseline information and underlying diseases. IL6 serum level (p=0.249) was not significantly difference between the two groups. However, IL17 serum level (p=0.012) demonstrated a significant difference between the two groups. Conclusion: In general, the results of this study showed that increased IL6 serum level following coronary artery bypass was not different between the two methods of CABG surgery. Besides, IL17 exhibited a significant difference between the two groupsi that it was reduced in on-pump group in after surgery. It can be due to special condition’s patients or low sample size of study. Moreover, the postoperative complications were not significantly different between the two groups. This valuable outcome contradicts the popular belief that the use of the CARDIO PULMONARY BYPASS (CPB) system stimulates the immune system and hence its application should be limited.
引言:本研究旨在根据血清白介素6(IL6)和白介素17(IL17)水平,探讨非体外循环和体外循环冠状动脉搭桥术在术后炎症严重程度中的作用。方法:这是一项横断面研究,其中39名患者的冠状动脉旁路移植术候选患者在非体外循环和体外循环两组手术前后的血清IL17和IL6水平进行了评估。结果:对39名患者进行了评估,在泵组中平均年龄为63±8.9,在非泵组中为59±7.74。在基线信息和潜在疾病方面,两组之间没有显著差异。IL6血清水平(p=0.249)在两组之间没有显著差异。然而,IL17血清水平(p=0.012)显示两组之间存在显著差异。结论:总的来说,本研究的结果表明,冠状动脉搭桥术后血清IL6水平的升高在两种CABG手术方法之间没有差异。此外,IL17在两组之间表现出显著差异,即在术后泵组IL17降低。这可能是由于特殊情况的患者或研究样本量低。此外,两组患者术后并发症无显著差异。这一有价值的结果与人们普遍认为的使用体外循环系统刺激免疫系统的观点相矛盾,因此其应用应该受到限制。
{"title":"A comparative study of interleukin 6 and 17 serum levels in patients undergoing coronary artery bypass surgery using off-pump and on-pump methods","authors":"Kambiz Alizadeh, A. Hosseinpour, M. Tabari, Majid Rajabian Noghondar, Narges Morovat, A. Izanloo","doi":"10.30483/RIJM.2020.254165.1019","DOIUrl":"https://doi.org/10.30483/RIJM.2020.254165.1019","url":null,"abstract":"Introduction: This study aims to investigate the role of coronary artery bypass graft (CABG) surgery by off-pump and on-pump methods in the severity of postoperative inflammation based on serum levels of interleukin 6 (IL6) and interleukin 17 (IL17). Methods: This is a cross-sectional study in which 39 patients’ candidate for CABG were evaluated in terms of serum levels of IL17 and IL6 before and after surgery in two groups of off-pump and on-pump CABG. Results: Thirty-nine patients with an average age of 63±8.9 in the on-pump group and 59±7.74 in the off-pump group were evaluated. There was no significant difference between the two groups in terms of baseline information and underlying diseases. IL6 serum level (p=0.249) was not significantly difference between the two groups. However, IL17 serum level (p=0.012) demonstrated a significant difference between the two groups. Conclusion: In general, the results of this study showed that increased IL6 serum level following coronary artery bypass was not different between the two methods of CABG surgery. Besides, IL17 exhibited a significant difference between the two groupsi that it was reduced in on-pump group in after surgery. It can be due to special condition’s patients or low sample size of study. Moreover, the postoperative complications were not significantly different between the two groups. This valuable outcome contradicts the popular belief that the use of the CARDIO PULMONARY BYPASS (CPB) system stimulates the immune system and hence its application should be limited.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"8 1","pages":"18-21"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49395561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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