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Regenerative medicine最新文献

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Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration 生物活性陶瓷材料:有益特性及在牙科修复和再生中的潜在应用
IF 2.7 4区 医学 Q1 Medicine Pub Date : 2024-05-22 DOI: 10.1080/17460751.2024.2343555
Jiale Wang, Linglin Zhang, Kun Wang
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引用次数: 0
PAX4 gene delivery improves β-cell function in human islets of Type II diabetes PAX4 基因递送可改善 II 型糖尿病人胰岛中 β 细胞的功能
IF 2.7 4区 医学 Q1 Medicine Pub Date : 2024-05-13 DOI: 10.1080/17460751.2024.2343538
Yanqing Zhang, Keshab R Parajuli, Vivian A Fonseca, Hongju Wu
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引用次数: 0
Use of allograft bone matrix in clinical orthopedics. 异体骨基质在临床骨科中的应用。
IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Pub Date : 2024-05-03 Epub Date: 2024-07-19 DOI: 10.1080/17460751.2024.2353473
Shaan Manawar, Erica Myrick, Peter Awad, Victor Hung, Cassidy Hinton, Keith Kenter, Karen Bovid, Yong Li

Clinical orthopedics continuously aims to improve methods for bone formation. Clinical applications where bone formation is necessary include critical long bone defects in orthopedic trauma or tumor patients. Though some biomaterials combined with autologous stem cells significantly improve bone repair, critical-size damages are still challenged with the suitable implantation of biomaterials and donor cell survival. Extracellular matrix (ECM) is the fundamental structure in tissues that can nest and nourish resident cells as well as support specific functions of the tissue type. ECM also plays a role in cell signaling to promote bone growth, healing and turnover. In the last decade, the use of bone-derived ECMs or ECM-similar biomaterials have been widely investigated, including decellularized and demineralized bone ECM. In this article, we reviewed the current productions and applications of decellularized and demineralized bone matrices. We also introduce the current study of whole limb decellularization and recellularization.

临床骨科一直致力于改进骨形成的方法。需要进行骨形成的临床应用包括骨科创伤或肿瘤患者的关键性长骨缺损。虽然一些生物材料与自体干细胞结合可显著改善骨修复,但临界大小的损伤仍面临生物材料的适当植入和供体细胞存活的挑战。细胞外基质(ECM)是组织的基本结构,可筑巢和滋养驻留细胞,并支持组织类型的特定功能。ECM 还在细胞信号传递中发挥作用,促进骨骼生长、愈合和新陈代谢。近十年来,人们广泛研究了骨源性 ECM 或类似 ECM 的生物材料的使用,包括脱细胞和脱矿物质骨 ECM。在这篇文章中,我们回顾了脱细胞和去矿物质骨基质目前的生产和应用情况。我们还介绍了目前对全肢脱细胞和再细胞化的研究。
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引用次数: 0
Industry updates from the field of stem cell research and regenerative medicine in January 2024. 2024 年 1 月干细胞研究和再生医学领域的行业动态。
IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Pub Date : 2024-05-03 Epub Date: 2024-03-13 DOI: 10.2217/rme-2024-0034
Dusko Ilic, Mirjana Liovic

Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in January 2024.

2024 年 1 月干细胞研究和再生医学领域的最新进展,根据公开信息和非学术机构的新闻稿汇编而成。
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引用次数: 0
Industry updates from the field of stem cell research and regenerative medicine in February 2024. 2024 年 2 月干细胞研究和再生医学领域的行业动态。
IF 2.7 4区 医学 Q1 Medicine Pub Date : 2024-04-24 DOI: 10.2217/rme-2024-0046
Dusko Ilic, M. Liovic
Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from non-academic institutions in February 2024.
2024 年 2 月干细胞研究和再生医学领域的最新进展,汇编自公开信息和非学术机构的新闻稿。
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引用次数: 0
Industry updates from the field of stem cell research and regenerative medicine in December 2023. 2023 年 12 月干细胞研究和再生医学领域的行业动态。
IF 2.7 4区 医学 Q1 Medicine Pub Date : 2024-04-01 Epub Date: 2024-02-15 DOI: 10.2217/rme-2024-0029
Dusko Ilic, Mirjana Liovic

Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from non-academic institutions in December 2023.

2023 年 12 月干细胞研究和再生医学领域的最新进展,汇编自公开信息和非学术机构的新闻稿。
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引用次数: 0
Peripheral nerve regeneration: a challenge far from being overcome. 外周神经再生:一个远未克服的挑战。
IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Pub Date : 2024-04-01 Epub Date: 2023-10-03 DOI: 10.2217/rme-2023-0072
Rui Alvites, Bruna Lopes, André Coelho, Ana Colette Maurício
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引用次数: 0
An assessment of co-contraction in reinnervated muscle. 再神经支配肌肉共收缩的评估。
IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Pub Date : 2024-04-01 Epub Date: 2023-11-13 DOI: 10.2217/rme-2023-0049
Matthew Wilcox, Hazel Brown, Kathryn Johnson, Marco Sinisi, Tom J Quick

Aim: To investigate co-contraction in reinnervated elbow flexor muscles following a nerve transfer. Materials & methods: 12 brachial plexus injury patients who received a nerve transfer to reanimate elbow flexion were included in this study. Surface electromyography (EMG) recordings were used to quantify co-contraction during sustained and repeated isometric contractions of reinnervated and contralateral uninjured elbow flexor muscles. Reuslts: For the first time, this study reveals reinnervated muscles demonstrated a trend toward higher co-contraction ratios when compared with uninjured muscle and this is correlated with an earlier onset of muscle fatigability. Conclusion: Measurements of co-contraction should be considered within muscular function assessments to help drive improvements in motor recovery therapies.

目的:探讨神经移植后肘关节屈肌的共收缩。材料与方法:本研究纳入12例臂丛神经损伤患者,接受神经转移术恢复肘关节屈曲。表面肌电图(EMG)记录用于量化再神经支配和对侧未损伤肘关节屈肌持续和重复等距收缩期间的共收缩。结果:本研究首次揭示了与未受伤肌肉相比,再神经支配肌肉表现出更高的共收缩率的趋势,这与肌肉疲劳的早期发作有关。结论:在肌肉功能评估中应考虑联合收缩的测量,以帮助推动运动恢复治疗的改进。
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引用次数: 0
Retraction: Photoencapsulated-BMP2 in visible light-cured thiol-acrylate hydrogels for craniofacial bone tissue engineering. 撤回:可见光固化硫醇-丙烯酸酯水凝胶中的光胶囊化 BMP2 用于颅面部骨组织工程。
IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Pub Date : 2024-04-01 Epub Date: 2024-03-05 DOI: 10.2217/rme-2020-0062r1
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引用次数: 0
Retraction: Photoencapsulated-mesenchymal stromal cells in biodegradable thiol-acrylate hydrogels enhance regeneration of craniofacial bone tissue defects. 撤回:生物可降解硫醇-丙烯酸酯水凝胶中的光胶囊化间充质基质细胞可促进颅面部骨组织缺损的再生。
IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Pub Date : 2024-04-01 Epub Date: 2024-03-05 DOI: 10.2217/rme-2020-0061r1
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引用次数: 0
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Regenerative medicine
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