Pub Date : 2024-02-14DOI: 10.36347/sajp.2024.v13i02.001
Stanislav V. Yefimov
We were tasked with testing a multicomponent aqueous solution for injection used in medicine. The composition of the solution included the following components: Riboflavin sodium phosphate (vitamin B2), Thiamine HCl (vitamin B1), Pyridoxine HCl (vitamin B), Dexpanthenol (vitamin B5), and Nicotinamide (vitamin B3), also benzyl alcohol. The complexity of the simultaneous determination of these components was that they differ in their acid-base properties, physical-chemical properties, concentration in solution, and solubility in the mobile phase. The key to solving this task is the correct choice of method for analyzing riboflavin sodium phosphate in each vitamin mixture. Riboflavin is taking particular attention because this component has a few isomers that are separated by HPLC.
{"title":"HPLC/MS Analysis of Riboflavin Sodium Phosphate Consisting of Several Structural Isomers Together with Thiamine HCL, Pyridoxine HCL, Dexpanthenol, and Nicotinamide in A Multi-Vitamin Injection Solution","authors":"Stanislav V. Yefimov","doi":"10.36347/sajp.2024.v13i02.001","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i02.001","url":null,"abstract":"We were tasked with testing a multicomponent aqueous solution for injection used in medicine. The composition of the solution included the following components: Riboflavin sodium phosphate (vitamin B2), Thiamine HCl (vitamin B1), Pyridoxine HCl (vitamin B), Dexpanthenol (vitamin B5), and Nicotinamide (vitamin B3), also benzyl alcohol. The complexity of the simultaneous determination of these components was that they differ in their acid-base properties, physical-chemical properties, concentration in solution, and solubility in the mobile phase. The key to solving this task is the correct choice of method for analyzing riboflavin sodium phosphate in each vitamin mixture. Riboflavin is taking particular attention because this component has a few isomers that are separated by HPLC.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"227 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140456757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-27DOI: 10.36347/sajp.2024.v13i01.005
Omar Shahir Alrashdan, Megbal Oudeh Alshurfat
Remote medical treatments have emerged; an example is the video conferences. These technologies serve patients who are geographically distant from medical centers. The integration of medical treatment with technology such as telemedicine in providing pediatric medical care has increased recently, leading to healthcare access simplifying disease management protocols, and improving the control of pediatric health status. The main objective of this study was to review the literature on the updated use of telemedicine in the current implications of telemedicine in pediatric healthcare. The results showed that the widespread of telemedicine in various disciplines of pediatric healthcare indicates its potential implications as technology advances.
{"title":"The Implications of Telemedicine in Pediatric Health: Integration of Technology into Medicine","authors":"Omar Shahir Alrashdan, Megbal Oudeh Alshurfat","doi":"10.36347/sajp.2024.v13i01.005","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i01.005","url":null,"abstract":"Remote medical treatments have emerged; an example is the video conferences. These technologies serve patients who are geographically distant from medical centers. The integration of medical treatment with technology such as telemedicine in providing pediatric medical care has increased recently, leading to healthcare access simplifying disease management protocols, and improving the control of pediatric health status. The main objective of this study was to review the literature on the updated use of telemedicine in the current implications of telemedicine in pediatric healthcare. The results showed that the widespread of telemedicine in various disciplines of pediatric healthcare indicates its potential implications as technology advances.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"25 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140493180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Globally recognized for its antifungal and anti-inflammatory properties, Calendula officinalis (Marigold) comprises various constituents, including carbohydrates, amino acids, terpenoids, glycosides, lipids, fatty acids, and carotenoids. In in-vitro assessments, it demonstrated effectiveness ranging from 54% to 79% against fungal infections, attributed to the significant presence of sesquiterpene, hydrocarbons, sesquiterpenols, δ-cadinene, α-cadinol, and epi-α-muurolol. Conversely, it also showcases robust cytotoxic activity against colon cancer, leukemia, and melanoma cells in human cancer lines, primarily due to the existence of two triterpene glycosides, calenduloside F 6¢-O-n-butyl ester, and calenduloside G 6¢-O-methyl ester.
金盏花（万寿菊）的抗真菌和消炎特性得到了全球公认，它含有多种成分，包括碳水化合物、氨基酸、萜类化合物、苷类、脂类、脂肪酸和类胡萝卜素。在体外评估中，它对真菌感染的有效率从 54% 到 79%不等，这归功于它含有大量的倍半萜、碳氢化合物、倍半萜醇、δ-cadinene、α-cadinol 和 epi-α-muurolol。相反，它还对人类癌症细胞系中的结肠癌、白血病和黑色素瘤细胞具有强大的细胞毒性活性，这主要是由于它含有两种三萜苷，即卡伦多甙 F 6¢-O-n-butyl 酯和卡伦多甙 G 6¢-O-methyl 酯。
{"title":"Calendula officinalis - A Crucial and Promising Antifungal Agent with Cytotoxic Biological Attributes","authors":"Hrithik Dey, Mahewish Tarannum, Pankaj Kumar, Vatsala Agarwal, Eliza Parvez, Md Naushad ali, Sufia Shafieq, Vikas Sharma","doi":"10.36347/sajp.2024.v13i01.004","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i01.004","url":null,"abstract":"Globally recognized for its antifungal and anti-inflammatory properties, Calendula officinalis (Marigold) comprises various constituents, including carbohydrates, amino acids, terpenoids, glycosides, lipids, fatty acids, and carotenoids. In in-vitro assessments, it demonstrated effectiveness ranging from 54% to 79% against fungal infections, attributed to the significant presence of sesquiterpene, hydrocarbons, sesquiterpenols, δ-cadinene, α-cadinol, and epi-α-muurolol. Conversely, it also showcases robust cytotoxic activity against colon cancer, leukemia, and melanoma cells in human cancer lines, primarily due to the existence of two triterpene glycosides, calenduloside F 6¢-O-n-butyl ester, and calenduloside G 6¢-O-methyl ester.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"81 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140495912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-16DOI: 10.36347/sajp.2024.v13i01.003
Ezeihuaku Amaka Perpetual, Ejiofor IfedibaluChukwu, Ajaghaku Daniel Lotanna, Ezugwu Christopher Obodike, Ibe Chioma Ifeoma
Background and Objectives: In Nigeria, traditional use of medicinal plants, like Chrysophyllum albidum, for diarrhoea persists. This study assessed its effectiveness in treating diarrhoea in rats. Methods: Extract and Fractions from the plant were tested for antidiarrhoea effect. The process involved methanol extraction and fractionation using hexane, ethyl acetate, and butanol. Rat models were used to evaluate the effects on castor oil-induced diarrhoea, enteropooling, and gastrointestinal motility. Results: Defecation caused by castor oil-induced diarrhoea was inhibited significantly by 53.55, 78.48 and 74.69 % at 500 mg/kg of methanol extract, ethyl acetate, and n-hexane fraction respectively, and by 50.99 and 63.69 % at 250 and 500 mg/kg of butanol fraction respectively. The volume of intestinal content and weight of intestinal content were reduced by 76.74 and 80 % at 500 mg/kg of ethyl acetate fraction. Also, the volume of intestinal content and weight of intestinal content were reduced by 70.93 and 70.83 % at 500 mg/kg of n-hexane fraction. At 250 and 500 mg/kg, the ethyl acetate fraction inhibited intestinal motility by 58.65% and 76.50% respectively. The n-hexane fraction at 500 mg/kg showed a 66.35% inhibition. Conclusion: These fractions from Chrysophyllum albidum leaves exhibit potential antidiarrhoea compounds, as evidenced across all three study models. Ongoing research aims to isolate these compounds for further investigation.
{"title":"In-Vivo Antidiarrhoea Evaluations of Methanol Leaf Extract and Fractions of Chrysophyllum albidum","authors":"Ezeihuaku Amaka Perpetual, Ejiofor IfedibaluChukwu, Ajaghaku Daniel Lotanna, Ezugwu Christopher Obodike, Ibe Chioma Ifeoma","doi":"10.36347/sajp.2024.v13i01.003","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i01.003","url":null,"abstract":"Background and Objectives: In Nigeria, traditional use of medicinal plants, like Chrysophyllum albidum, for diarrhoea persists. This study assessed its effectiveness in treating diarrhoea in rats. Methods: Extract and Fractions from the plant were tested for antidiarrhoea effect. The process involved methanol extraction and fractionation using hexane, ethyl acetate, and butanol. Rat models were used to evaluate the effects on castor oil-induced diarrhoea, enteropooling, and gastrointestinal motility. Results: Defecation caused by castor oil-induced diarrhoea was inhibited significantly by 53.55, 78.48 and 74.69 % at 500 mg/kg of methanol extract, ethyl acetate, and n-hexane fraction respectively, and by 50.99 and 63.69 % at 250 and 500 mg/kg of butanol fraction respectively. The volume of intestinal content and weight of intestinal content were reduced by 76.74 and 80 % at 500 mg/kg of ethyl acetate fraction. Also, the volume of intestinal content and weight of intestinal content were reduced by 70.93 and 70.83 % at 500 mg/kg of n-hexane fraction. At 250 and 500 mg/kg, the ethyl acetate fraction inhibited intestinal motility by 58.65% and 76.50% respectively. The n-hexane fraction at 500 mg/kg showed a 66.35% inhibition. Conclusion: These fractions from Chrysophyllum albidum leaves exhibit potential antidiarrhoea compounds, as evidenced across all three study models. Ongoing research aims to isolate these compounds for further investigation.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139620534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.36347/sajp.2023.v12i12.006
Ann Rose Joseph, Geetha Jayaprakash, Udayakumar Udayakumar
Epilepsy is a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain. The incidence of epilepsy is highest during childhood, especially for children aged 0 - 14 years. The goal of the study is find out the prescribing pattern of antiepileptic drugs in different types of seizure disorder in children. An educational observational study was carried out among 55 samples in the In-patient Department of Pediatrics, in a tertiary care teaching hospital, Bangalore. The data was collected by using self-designed data collection form. All information’s were processed and analyzed by using Microsoft excel. In the present study, breakthrough seizures was the most commonly observed type of seizure followed by simple febrile seizure. The most commonly prescribed antiepileptic drug was levetiracetam, followed by clobazam in monotherapy. Majority of the patients were prescribed with monotherapy followed by dual therapy. Levetiracetam + Clobazam, Levetiracetam + Sodium valproate and Levetiracetam + Phenytoin was the most preferred combination. Drug use pattern of Antiepileptic Drugs was described based on WHO prescription indicators, which shows out of 55 sample size, average number of drugs per encounter was 0.5, 44% of injections were encountered, antibiotics prescribed were 0%, drug prescribed based on generic name were 54% and 93% of drug was encountered based on essential drug list. Antiepileptic prescribing in this study population was only 56% in accordance to the ILAE treatment guidelines for epilepsy.
{"title":"Prescription Pattern of Antiepileptic Drugs in Different Types of Seizure Disorder in Children","authors":"Ann Rose Joseph, Geetha Jayaprakash, Udayakumar Udayakumar","doi":"10.36347/sajp.2023.v12i12.006","DOIUrl":"https://doi.org/10.36347/sajp.2023.v12i12.006","url":null,"abstract":"Epilepsy is a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain. The incidence of epilepsy is highest during childhood, especially for children aged 0 - 14 years. The goal of the study is find out the prescribing pattern of antiepileptic drugs in different types of seizure disorder in children. An educational observational study was carried out among 55 samples in the In-patient Department of Pediatrics, in a tertiary care teaching hospital, Bangalore. The data was collected by using self-designed data collection form. All information’s were processed and analyzed by using Microsoft excel. In the present study, breakthrough seizures was the most commonly observed type of seizure followed by simple febrile seizure. The most commonly prescribed antiepileptic drug was levetiracetam, followed by clobazam in monotherapy. Majority of the patients were prescribed with monotherapy followed by dual therapy. Levetiracetam + Clobazam, Levetiracetam + Sodium valproate and Levetiracetam + Phenytoin was the most preferred combination. Drug use pattern of Antiepileptic Drugs was described based on WHO prescription indicators, which shows out of 55 sample size, average number of drugs per encounter was 0.5, 44% of injections were encountered, antibiotics prescribed were 0%, drug prescribed based on generic name were 54% and 93% of drug was encountered based on essential drug list. Antiepileptic prescribing in this study population was only 56% in accordance to the ILAE treatment guidelines for epilepsy.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"24 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.36347/sajp.2023.v12i12.007
Namitha S, Vaishnavi Prasannan
Poor and insufficient glycaemia management in people with Type 2 diabetes mellitus (DM) is a major public health issue that hastens the onset of diabetes related complications. Poor medication adherence among type2 diabetes mellitus patients is associated with inadequate glycaemia control, increased hospitalization, increase the risk of complications, increased mortality and morbidity. The main objectives of the study was to assess patient related factors associated with medication adherence and assess knowledge about diabetes and related complications among type II diabetes mellitus patients visiting an out-patient clinic, Bangalore. Data was entered and analyzed by using Microsoft excel and SPSS 22 version 29.0. It was found that, mean age of the study subjects was 49.89 years, majority of the subjects were male, of the respondents 30 (51.7%), 19 (32.75%) and 9 (15.5%) had good, average and poor level of diabetic knowledge respectively. 34 (59%) and 24 (41%) were adherent and non-adherent respectively. In this study, factors like male gender, having higher income, high socio-economic levels, following diabetic diet, maintaining physical activity on a regular basis, good knowledge about the disease and having stronger beliefs about medicines and their use were highly adherent to anti-diabetic medications indicating high medication adherence levels. Healthcare professionals such as pharmacists should implement effective health education interventions required to improve diabetes knowledge and beliefs regarding the disease and medications for better management of the disease which thereby results in improved quality of life, in addition medication compliance ensures a strategic diabetic management and
{"title":"Assessment of Patient Related Factors Associated with Medication Adherence in type II Diabetes Mellitus","authors":"Namitha S, Vaishnavi Prasannan","doi":"10.36347/sajp.2023.v12i12.007","DOIUrl":"https://doi.org/10.36347/sajp.2023.v12i12.007","url":null,"abstract":"Poor and insufficient glycaemia management in people with Type 2 diabetes mellitus (DM) is a major public health issue that hastens the onset of diabetes related complications. Poor medication adherence among type2 diabetes mellitus patients is associated with inadequate glycaemia control, increased hospitalization, increase the risk of complications, increased mortality and morbidity. The main objectives of the study was to assess patient related factors associated with medication adherence and assess knowledge about diabetes and related complications among type II diabetes mellitus patients visiting an out-patient clinic, Bangalore. Data was entered and analyzed by using Microsoft excel and SPSS 22 version 29.0. It was found that, mean age of the study subjects was 49.89 years, majority of the subjects were male, of the respondents 30 (51.7%), 19 (32.75%) and 9 (15.5%) had good, average and poor level of diabetic knowledge respectively. 34 (59%) and 24 (41%) were adherent and non-adherent respectively. In this study, factors like male gender, having higher income, high socio-economic levels, following diabetic diet, maintaining physical activity on a regular basis, good knowledge about the disease and having stronger beliefs about medicines and their use were highly adherent to anti-diabetic medications indicating high medication adherence levels. Healthcare professionals such as pharmacists should implement effective health education interventions required to improve diabetes knowledge and beliefs regarding the disease and medications for better management of the disease which thereby results in improved quality of life, in addition medication compliance ensures a strategic diabetic management and","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-16DOI: 10.36347/sajp.2023.v12i12.003
N. Nchinech, Omar Benhasna, Sanae Achour, Abdesselam Elkartouti, Yassir Bousliman, J. Lamsaouri, Y. Tadlaoui
Medication errors are a problem that has always threatened the well-being of patients, in our study we will highlight one of the most common causes, it is the Look Alike and Sound Alike medications that can contribute to up to 25% of all medication errors and harm about 250,000 people a year. Also causes several difficulties for health professionals, either in hospitals or in pharmacies. This is a descriptive and analytical cross-sectional study with health professionals in pharmacies and hospitals, which took place between 2022/02/22 and 2022/08/11, in the form of an anonymous questionnaire, The statistical study was carried out with the Jamovi software and Microsoft Excel. One hundred and thirty four responses were received, divided between 71 for pharmacies and 63 for hospitals, targeting services with a high workload. A percentage of 87% of participants from pharmacies confirm that they are already confronted with medicines with similarities either at the level of packaging or at the nomenclature, 71% of hospital participants also confirm it, and among all participants 58% are already facing medication errors caused by these types of drugs. Our study can confirm that the problem of Look Alike and Sound Alike drugs is as always a serious problem, which needs more vigilance at the different levels of drug use, there are also international recommendations issued to minimize the risk of these medications.
{"title":"Medication Errors Related to Look Alike and Sound Alike Medications: About a Moroccan City University Hospital and Community Pharmacies Experience","authors":"N. Nchinech, Omar Benhasna, Sanae Achour, Abdesselam Elkartouti, Yassir Bousliman, J. Lamsaouri, Y. Tadlaoui","doi":"10.36347/sajp.2023.v12i12.003","DOIUrl":"https://doi.org/10.36347/sajp.2023.v12i12.003","url":null,"abstract":"Medication errors are a problem that has always threatened the well-being of patients, in our study we will highlight one of the most common causes, it is the Look Alike and Sound Alike medications that can contribute to up to 25% of all medication errors and harm about 250,000 people a year. Also causes several difficulties for health professionals, either in hospitals or in pharmacies. This is a descriptive and analytical cross-sectional study with health professionals in pharmacies and hospitals, which took place between 2022/02/22 and 2022/08/11, in the form of an anonymous questionnaire, The statistical study was carried out with the Jamovi software and Microsoft Excel. One hundred and thirty four responses were received, divided between 71 for pharmacies and 63 for hospitals, targeting services with a high workload. A percentage of 87% of participants from pharmacies confirm that they are already confronted with medicines with similarities either at the level of packaging or at the nomenclature, 71% of hospital participants also confirm it, and among all participants 58% are already facing medication errors caused by these types of drugs. Our study can confirm that the problem of Look Alike and Sound Alike drugs is as always a serious problem, which needs more vigilance at the different levels of drug use, there are also international recommendations issued to minimize the risk of these medications.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"60 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138967204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Off-Label use of Medications in Pediatrics: Problem or Miracle Solution?","authors":"N. Nchinech, adreddine Moukafih, B, Sanae Achour, Abdesselam Elkartouti, Yassir Bousliman","doi":"10.36347/sajp.2023.v12i12.004","DOIUrl":"https://doi.org/10.36347/sajp.2023.v12i12.004","url":null,"abstract":"","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"24 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138967573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-16DOI: 10.36347/sajp.2023.v12i12.005
Abdulazez Sabri Salh, Abdurahman Alyousef, Fahad Abdullah AL-Bulwi, Saud Mohammed Al-Khaldi, Azzah Ali Sanbi, Eeyed Ali Alalawy, Nader Salem AlBalawi, Faris Ahmed Hakami, Abdullah Masoud Magrashi
Background: Although pharmacists have traditionally been involved in dispensing medications and providing patient counseling, there is mounting evidence that they may improve the clinical and humanistic outcomes for people with diabetes via a variety of supplementary services. The objective of the study is to determine the Knowledge, attitude and practice of pharmacist’s in Tabuk, Saudi Arabia about Type II Diabetes Mellitus. Methods: This was a cross sectional study conducted at Department of Pharmacy, King Salman Armed forces hospital, Tabuk Kingdom of Saudi Arabia. A total of 110 study participants were included in the study. Data was collected with the help of a predesigned questionnaire containing closed ended questions regarding knowledge, attitude and practice of pharmacists toward type II diabetic patients care. Data entry and analysis was done with the help of SPSS version 25. Results: In this study 69.10% of the pharmacists were strongly agree/agree on their prominent role in diabetic patient care. About 77.30% pharmacists were strongly agree/agree for the fact that prescribing physicians are the only professionals who need to understand and 86.40% were strongly agree/agree that pharmacist role can improve diabetic patient care. Among pharmacists 60% were strongly agree/agree for that fact that their role can minimize the medications related complaints. Attitude and practice towards medicine dispensing and related aspect of dispensing were aligned to the standard protocols in their hospital. i.e. screening of prescription, collaboration and communication with health professional/prescriber, education of the patients, participating in workshops related to diabetic patient care and counseling of patients. Conclusion: Results of this study demonstrate that pharmacists had good knowledge, attitude and practice towards their basic dispensing role for type II diabetic patients. But they were full aware of their extended role which can be helpful for ......
背景：尽管药剂师传统上一直从事配药和为患者提供咨询服务，但越来越多的证据表明，他们可以通过各种辅助服务改善糖尿病患者的临床和人文治疗效果。本研究旨在了解沙特阿拉伯塔布克市药剂师对 II 型糖尿病的认识、态度和做法。研究方法这是一项在沙特阿拉伯王国塔布克萨勒曼国王武装部队医院药剂部进行的横断面研究。共有 110 名参与者参与了研究。数据收集采用了预先设计的调查问卷，其中包含有关药剂师对 II 型糖尿病患者护理的知识、态度和实践的封闭式问题。数据输入和分析在 SPSS 25 版本的帮助下完成。结果在这项研究中，69.10% 的药剂师非常同意/同意他们在糖尿病患者护理中的突出作用。约 77.30% 的药剂师非常同意/同意开处方的医生是唯一需要了解的专业人员，86.40% 的药剂师非常同意/同意药剂师的角色可以改善糖尿病患者护理。药剂师中有 60% 的人非常同意/同意他们的角色可以最大限度地减少与药物有关的投诉。药剂师对配药的态度和做法以及配药的相关方面均符合其所在医院的标准规定，即筛选处方、与医疗专业人员/开处方者合作和沟通、教育患者、参加与糖尿病患者护理和患者咨询有关的研讨会。结论研究结果表明，药剂师对其为 II 型糖尿病患者配药的基本职责具有良好的认识、态度和实践。但他们充分认识到自己的延伸角色，这对 ...... 有帮助。
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Pub Date : 2023-12-09DOI: 10.36347/sajp.2023.v12i12.002
Joshy George Zachariah, Geetha Jayaprakash, Suchitra Suchitra, Glory Susan Zachariah, Chandrani Das
Lung cancer develops when lung cells divide rapidly, which leads to the growth of tumors. It is the most prevalent cancer and the major factor in men's cancer-related mortality. The goal of the study is to assess prescription pattern in patients receiving chemotherapy for lung cancer. A study on prescription pattern will help in optimizing the anti-malignancy therapy with improved efficacy & minimal toxicity. This study assesses prescription pattern in patients receiving chemotherapy for lung cancer. This was a prospective observational study carried out in the Out-patient Department of Oncology in tertiary care teaching hospital, Bengaluru. A total of 37 samples were collected, of which 31 were selected for the study. Subjects for the study were identified by the investigator during ward rounds based on the inclusion and exclusion criteria. Relevant data collected were recorded on the Self-designed data collection form. All recorded data were entered and analyzed using MS Excel. Descriptive statistics were computed for quantitative variables. The majority of the subjects involved in the study were prescribed with Carboplatin. Carboplatin with Pemetrexed Disodium was the most preferred combination therapy. In the present study, we have concluded that the oncologists in this hospital prefer Cytotoxic and Targeted drugs over Hormonal drugs for the treatment of lung cancer.
肺癌是肺细胞迅速分裂导致肿瘤生长而形成的。它是发病率最高的癌症，也是男性癌症相关死亡率的主要因素。这项研究的目的是评估肺癌化疗患者的处方模式。对处方模式的研究将有助于优化抗恶性肿瘤疗法，提高疗效，减少毒性。本研究评估了肺癌化疗患者的处方模式。这是一项前瞻性观察研究，在班加罗尔三级教学医院肿瘤科门诊部进行。共收集了 37 份样本，其中 31 份被选中用于研究。研究人员在查房时根据纳入和排除标准确定了研究对象。收集到的相关数据记录在自行设计的数据收集表上。所有记录的数据均使用 MS Excel 进行输入和分析。对定量变量进行了描述性统计。参与研究的大多数受试者都服用了卡铂。卡铂和培美曲塞二钠是最受欢迎的联合疗法。在本研究中，我们得出的结论是，在治疗肺癌时，该医院的肿瘤专家更倾向于细胞毒性和靶向药物，而不是激素类药物。
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