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Ultra-processed food consumption and obesity among children and adolescents in China—Findings from China Health and Nutrition Survey 中国儿童和青少年的超加工食品消费与肥胖——中国健康与营养调查结果
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-03-12 DOI: 10.1111/ijpo.70012
Ming Li, Zumin Shi

Background

Children and adolescents are increasingly exposed to processed food in China, however, its association with obesity has not been investigated.

Objectives

To assess the consumption of ultra-processed food (UPF) and its association with overweight/obesity among children and adolescents in China.

Methods

A total of 3437 children and adolescents aged 6–18 years, participating at least twice in the China Nutrition and Health Survey, were included. Food intake was collected using a 3-day 24-h dietary recall method at home visits. Body weight, height and waist circumference (WC) were measured during the survey. UPF was defined by food process levels using NOVA classification. Overweight/obesity was defined by the international age- and sex-specific BMI and WC cut-offs. The association between UPF consumption and overweight/obesity was assessed using mixed effect logistic regression analyses adjusted for socio-demographic, economic, behavioural, dietary and health factors.

Results

The mean daily UPF consumption of the study population (mean age 9.3 years) increased from 9.7 in 1997 to 60.0 grams in 2011. The adjusted odds ratios (OR) (95% CI) for overweight/obesity (using BMI) for UPF consumption of 0, 1–49, 50–99 and ≥ 100 g/day were 1.00, 1.38 (0.98–1.94), 2.01 (1.25–3.24) and 1.53 (0.82–2.86), respectively (p-trend =0.013). Similarly, the corresponding adjusted ORs (95% CI) for central obesity (using WC) were 1.00, 1.84 (1.30–2.60), 2.13 (1.30–3.48) and 2.15 (1.14–4.05) (p-trend<0.001).

Conclusions

Higher long-term UPF consumption was associated with an increased risk of overweight/obesity among children and adolescents in China.

背景:在中国,儿童和青少年越来越多地接触加工食品,然而,其与肥胖的关系尚未得到调查。目的:评估中国儿童和青少年超加工食品(UPF)的消费及其与超重/肥胖的关系。方法:选取至少两次参加中国营养与健康调查的3437名6-18岁儿童和青少年为研究对象。采用3天24小时家访饮食回忆法收集食物摄入量。在调查中测量了体重、身高和腰围(WC)。UPF由食品加工水平定义,使用NOVA分类。超重/肥胖由国际年龄和性别特定的BMI和WC截断值定义。UPF消费与超重/肥胖之间的关系采用混合效应逻辑回归分析进行评估,调整了社会人口、经济、行为、饮食和健康因素。结果:研究人群(平均年龄9.3岁)的平均每日UPF摄入量从1997年的9.7克增加到2011年的60.0克。UPF摄入量为0、1-49、50-99和≥100 g/d时,超重/肥胖(使用BMI)的校正优势比(OR) (95% CI)分别为1.00、1.38(0.98-1.94)、2.01(1.25-3.24)和1.53 (0.82-2.86)(p-trend =0.013)。同样,中心性肥胖(使用WC)的相应调整后的or (95% CI)分别为1.00、1.84(1.30-2.60)、2.13(1.30-3.48)和2.15 (1.14-4.05)(p趋势)。结论:中国儿童和青少年长期UPF摄入量较高与超重/肥胖风险增加相关。
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引用次数: 0
Association between excessive screen time and steatotic liver disease in adolescents: Findings from the 2017–2018 National Health and Nutrition Examination Survey 青少年屏幕时间过长与脂肪变性肝病之间的关系:来自2017-2018年全国健康和营养检查调查的结果
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-03-11 DOI: 10.1111/ijpo.70010
Shaoxun Li, Shuanghong Jin, Peipei Fang, Chenwei Pan, Shanshan Huang

Introduction

Screen-based behaviours have brought great changes to our lifestyles over the last 50 years. There is limited data evaluating the effects of such alterations on the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in adolescents. This study sets out to assess possible associations of excessive screen exposure with liver steatosis in a representative sample of US adolescents.

Methods

This cross-sectional analysis used data derived from the National Health and Nutrition Examination Surveys (NHANES) carried out in 2017–2018, including 731 subjects aged 12–17 years. Self-reported screen time (ST, hours/day) outside of school was recorded, including hours watching TV or videos and hours using the computer. Liver steatosis was identified according to the median controlled attenuation parameter (CAP) by transient elastography.

Results

Among the participants, 476 (65.0%, 95% CI: 60.7%–69.2%) experienced excessive screen time (EST, daily ST ≥ 5 h). The prevalence of liver steatosis was higher in adolescents with EST versus counterparts with modest ST (ST < 5 h) (27.0% vs. 16.1%, p < 0.001). EST was associated with increased odds of liver steatosis in adolescents after adjusting for covariates related to demographic background, metabolic variables, physical activity and diet quality (OR: 2.10, 95% CI: 1.34–3.29, p = 0.032). Body mass index partially mediated the effect of EST on liver steatosis risk (52.9%, p = 0.036).

Conclusion

Excessive screen time was associated with increased odds of liver steatosis in adolescents. Strategies to reduce screen time for youth may bring benefits for the management of MASLD.

在过去的50年里,基于屏幕的行为给我们的生活方式带来了巨大的变化。评估这种改变对青少年代谢功能障碍相关脂肪变性肝病(MASLD)患病率的影响的数据有限。本研究旨在评估美国青少年代表性样本中过度屏幕暴露与肝脏脂肪变性的可能关联。方法:采用2017-2018年国家健康与营养检查调查(NHANES)的数据进行横断面分析,其中包括731名12-17岁的受试者。自我报告的课外屏幕时间(ST,小时/天)被记录下来,包括看电视或视频的时间和使用电脑的时间。根据瞬时弹性成像中值控制衰减参数(CAP)识别肝脏脂肪变性。结果:在参与者中,476人(65.0%,95% CI: 60.7%-69.2%)经历过屏幕时间过长(EST,每日ST≥5小时)。结论:过多的屏幕时间与青少年肝脏脂肪变性的几率增加有关。减少青少年屏幕时间的策略可能会为管理MASLD带来好处。
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引用次数: 0
Impact of the Play Active policy intervention on early childhood educator's sedentary behaviour-related practices, psychosocial influences and meeting policy recommendations: Results from a pragmatic cluster randomized trial 积极游戏政策干预对幼儿教育者久坐行为相关实践、心理社会影响和满足政策建议的影响:来自实用集群随机试验的结果
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-03-11 DOI: 10.1111/ijpo.70005
Hayley Christian, Andrea Nathan, Emma Adams, Stewart G. Trost, Jasper Schipperijn

Background

High levels of sedentary behaviour are associated with poor child health outcomes such as obesity. Early childhood education and care (ECEC) services are a key intervention setting. Most ECEC policy-based interventions focus on children's nutrition and physical activity with few aimed at children's sedentary behaviour.

Objective

To evaluate the effect of the Play Active ECEC policy intervention on educator adherence to sedentary behaviour policy recommendations, educator's practices and educator psychosocial influences related to children's sedentary behaviour.

Methods

Pragmatic cluster randomized trial in 81 ECEC services in Perth, Western Australia. Services implemented the Play Active policy over three months. Outcomes were educator-reported changes in adherence to sedentary behaviour policy recommendations, practices and psychosocial influences related to children's sedentary behaviour. Analysis involved descriptive statistics and generalized linear mixed-effects models.

Results

Adherence to sedentary behaviour policy recommendations and educator's practices and psychosocial influences related to children's sedentary behaviour was high at baseline and did not significantly change in response to the Play Active policy intervention.

Conclusions

Educators appeared to adhere to best-practice guidelines for children's sedentary behaviour in ECEC. Clear evidence informed policy, standards and legislation to maintain children's low levels of sedentary behaviours in ECEC is warranted.

背景:长时间的久坐行为与儿童健康状况不佳有关,如肥胖。幼儿教育和护理(ECEC)服务是一个关键的干预环境。大多数基于ECEC政策的干预措施侧重于儿童的营养和身体活动,很少针对儿童的久坐行为。目的:评价儿童久坐行为相关的教育工作者对久坐行为政策建议的依从性、教育工作者的行为以及教育工作者的心理社会影响。方法:对西澳大利亚珀斯81家ECEC服务机构进行语用群随机试验。服务部门在三个月内执行了Play Active政策。结果是教育工作者报告的坚持久坐行为政策建议、实践和与儿童久坐行为相关的心理社会影响的变化。分析涉及描述性统计和广义线性混合效应模型。结果:坚持久坐行为政策建议和教育工作者的做法以及与儿童久坐行为相关的心理社会影响在基线时很高,并且对积极玩耍政策干预的反应没有显着变化。结论:教育工作者似乎坚持在ECEC中儿童久坐行为的最佳实践指南。有明确证据支持的政策、标准和立法,以维持ECEC儿童低水平的久坐行为是必要的。
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引用次数: 0
Gut microbiota and microbial metabolites are associated with body composition in 5-year-old children: A cross-sectional study in the Gen3G cohort 5岁儿童肠道菌群和微生物代谢物与身体组成相关:Gen3G队列的横断面研究
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-03-10 DOI: 10.1111/ijpo.70007
Yingan Chen, Curtis Tilves, Bruno Bohn, Myriam Doyon, Luigi Bouchard, Patrice Perron, Renee Guerin, Eric Masse, Marie-France Hivert, Noel T. Mueller

Objective

To examine gut microbiota diversity, composition and metabolites in relation to overall mass (OM), fat mass (FM) and lean soft tissue mass (LSTM) measured by dual x-ray absorptiometry (DXA) in 5-year-old children.

Methods

Mothers of the Gen3G cohort were enrolled prenatally in 2010–2013 in Quebec, Canada; 153 children from the cohort had data on gut microbiota and DXA scans at 5–6.4 years of age, and 140 also had plasma metabolite data. We characterized gut microbiota by 16S rRNA Illumina sequencing and metabolites by untargeted multiplatform mass spectrometry. We examined associations of microbial alpha diversity, beta diversity, composition (amplicon sequence variants; ASVs) and metabolites (microbial metabolites) with DXA measures, adjusting for age, sex, diet and drinking water.

Results

Of the 153 children, 43.1% were female, and 96.1% self-identified as white. The median BMI was the 52nd percentile. Microbial richness (alpha diversity) was positively associated with OM, FM and LSTM. Of the 542 ASVs tested, 7 were associated with OM, 5 with FM and 4 with LSTM. One Veillonella ASV and two Blautia ASVs were significantly associated with all outcomes. Among 278 microbial metabolites, no metabolites were associated with FM, while glycoursodeoxycholate was associated with OM, and glycoursodeoxycholate, 3-hydroxybutyrate and gamma-glutamylalanine were associated with LSTM.

Conclusions

In 5-year-old children, gut microbiota alpha diversity, richness and specific gut microbes were associated with OM, FM and LSTM. Many of the associations followed a similar pattern for FM and LSTM, suggesting they may not be specific to adiposity but rather reflect overall growth.

目的:探讨双x线吸收仪(DXA)测定5岁儿童肠道菌群多样性、组成和代谢产物与总质量(OM)、脂肪质量(FM)和瘦软组织质量(LSTM)的关系。方法:2010-2013年在加拿大魁北克省招募Gen3G队列的母亲;该队列中的153名儿童在5-6.4岁时具有肠道微生物群和DXA扫描数据,140名儿童还具有血浆代谢物数据。我们通过16S rRNA Illumina测序和非靶向多平台质谱分析来表征肠道微生物群。我们研究了微生物α多样性、β多样性、组成(扩增子序列变异;asv)和代谢物(微生物代谢物)与DXA测量,调整年龄,性别,饮食和饮用水。结果:153名儿童中,女性占43.1%,白人占96.1%。BMI的中位数是第52个百分位数。微生物丰富度(α多样性)与OM、FM和LSTM呈正相关。在测试的542例asv中,7例与OM相关,5例与FM相关,4例与LSTM相关。1例细络性ASV和2例布劳蒂亚性ASV与所有结果显著相关。278种微生物代谢物中,没有代谢物与FM相关,而甘coursodeoxycholate与OM相关,甘coursodeoxycholate、3-羟基丁酸盐和γ -谷氨酰丙氨酸与LSTM相关。结论:在5岁儿童中,肠道菌群α多样性、丰富度和特异性肠道微生物与OM、FM和LSTM相关。许多关联遵循了FM和LSTM的类似模式,这表明它们可能不是肥胖所特有的,而是反映了整体的增长。
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引用次数: 0
A systematic review of prevention strategies for type 2 diabetes in First Nations children and young people 第一民族儿童和青少年2型糖尿病预防策略的系统综述。
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-03-10 DOI: 10.1111/ijpo.70009
Marylin Carino, Jonathan Nguyen, Ru Hui New, Renae Kirkham, Louise Maple-Brown, Shiree Mack, Diana MacKay, Angela Titmuss

Introduction

There is a high prevalence of type 2 diabetes (T2D) in First Nations populations worldwide, increasingly at younger ages. This review aims to identify interventions for the prevention of T2D in First Nations children and young people aged 4–25 years.

Methods

A systematic search of both published and unpublished literature until March 2024 was performed using 15 electronic databases, including MEDLINE, CINAHL, EMBASE, Scopus, Cochrane Library, ATSIHealth, OpenGrey and specific First Nations databases. Eligible studies included First Nations participants aged 4–25 years without T2D, exploring interventions to prevent T2D. Outcomes included knowledge of diabetes, anthropometry and physiology, diet and nutrition, physical activity, glycemic indicators and psychosocial indicators.

Results

Fourteen pre–post exposure non-controlled studies were included, evaluating nine programs. Programs were culturally adapted and primarily school-based, focusing on individual-level behaviour modification in nutrition and physical activity. Most studies assessing knowledge outcomes reported improvement. There were inconsistent findings regarding impacts on dietary intake and glycemia. One home-based program achieved improvements across a range of outcomes, including body mass index, physical activity and psychosocial scores.

Conclusion

Despite the increasing prevalence of T2D in First Nations children and young people, evidence of effective preventive strategies within these populations remains limited.

导读:2型糖尿病(T2D)在世界范围内的原住民人群中有很高的患病率,并且越来越多地发生在年轻人群中。本综述旨在确定预防原住民儿童和4-25岁年轻人T2D的干预措施。方法:使用MEDLINE、CINAHL、EMBASE、Scopus、Cochrane Library、ATSIHealth、OpenGrey和特定的First Nations数据库等15个电子数据库,系统检索截至2024年3月的已发表和未发表文献。符合条件的研究包括4-25岁无T2D的第一民族参与者,探索预防T2D的干预措施。结果包括糖尿病知识、人体测量学和生理学、饮食和营养、身体活动、血糖指标和社会心理指标。结果:纳入14项暴露前后非对照研究,评估了9个方案。这些项目与文化相适应,主要以学校为基础,侧重于营养和体育活动方面的个人行为改变。大多数评估知识成果的研究都报告了改善。关于饮食摄入和血糖的影响有不一致的发现。一个以家庭为基础的项目在一系列结果上取得了改善,包括身体质量指数、身体活动和心理社会得分。结论:尽管原住民儿童和年轻人中T2D患病率不断上升,但在这些人群中有效预防策略的证据仍然有限。
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引用次数: 0
Factors that shape dietary intake in children in the context of increasing risk for obesity development 在增加肥胖发展风险的背景下,影响儿童饮食摄入的因素。
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-03-06 DOI: 10.1111/ijpo.70004
Michael I. Goran, Alexandra Descarpentrie, Shana Adise

The development of obesity in childhood is the result of interplay between a complex array of multi-level factors, one of which is dietary intake. However, dietary intake in childhood itself is impacted by many factors operating at different levels. This special issue brings together a collection of papers that examine various factors influencing children's dietary intake. Rather than issuing a call for papers, this collection came together organically based on regular submissions, highlighting the growing body of research dedicated to understanding how children's dietary habits can contribute to obesity risk. These papers represent studies that have focused on the external (e.g., fast-food environment, ongoing rapid proliferation of ultra-processed foods) and social (e.g., the role of parents and schools, stress and adversity) environment, behavioural factors (e.g., reward and gratification, sleeping behaviour) and genetic factors, as well as maternal factors that promote intra-generational transmission. This is summarized in Figure 1. In a time when obesity development continues to rise globally, these studies may shed light on the complexity of one of the main drivers, namely dietary intake. Below we summarize the latest research in these areas resulting from the papers in this Special Issue.

儿童期肥胖的发展是一系列多层次复杂因素相互作用的结果,其中之一是饮食摄入。然而,儿童时期的饮食摄入本身受到许多不同水平的因素的影响。本期特刊汇集了一系列研究影响儿童饮食摄入的各种因素的论文。这个合集并没有发出征文的号召,而是在定期提交的基础上有机地聚集在一起,突显出越来越多的研究致力于了解儿童的饮食习惯如何导致肥胖风险。这些论文代表的研究集中在外部(例如,快餐环境,超加工食品的持续快速扩散)和社会(例如,父母和学校的作用,压力和逆境)环境,行为因素(例如,奖励和满足,睡眠行为)和遗传因素,以及促进代际传播的母亲因素。图1总结了这一点。在全球肥胖发展持续上升的时代,这些研究可能揭示了主要驱动因素之一的复杂性,即饮食摄入。下面我们将从本期特刊的论文中总结出这些领域的最新研究成果。
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引用次数: 0
Nutrition transition's latest stage: Are ultra-processed food increases in low- and middle-income countries dooming our preschoolers' diets and future health? 营养转型的最新阶段:中低收入国家超加工食品的增加是否会影响我们学龄前儿童的饮食和未来的健康?
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-02-26 DOI: 10.1111/ijpo.70002
Barry M. Popkin, Amos Laar

Introduction

Rapid shifts in dietary patterns, marked by increased consumption of ultra-processed foods (UPFs), are increasingly impacting the health and wellbeing of infants and toddlers in low- and middle-income countries.

Methods

Utilizing data from the Demographic and Health Surveys, other national surveys, NCD-RisC data and Euromonitor sales data, we examine changes in stunting and overweight/obesity prevalence alongside the latest data on UPF consumption trends.

Results

The prevalence of overweight/obesity among children and mothers is increasing rapidly while stunting rates decline slowly. Simultaneously, there is a significant increase in consumption of UPFs, especially among preschool-aged children. Increasingly, poorer households are experiencing faster rates of increase in overweight and obesity prevalence compared to wealthier households. Results highlight the early socialization of infants and toddlers to unhealthy discretionary foods including UPFs, potentially setting the stage for long-term dietary preferences that favour food with high sugar or excess sodium.

Conclusion

There is an urgent need to address the rapid increases in UPF consumption among infants and toddlers. Options include expanding the WHO Code on marketing to protect 0–3-year-olds; creating front-of-package warning labels focusing on products for children ages 0–3 years to remove all added sugar and limit sodium in foods and beverages they consume.

导言:以超加工食品消费增加为标志的饮食模式的快速变化,正日益影响低收入和中等收入国家婴幼儿的健康和福祉。方法:利用来自人口与健康调查、其他国家调查、NCD-RisC数据和Euromonitor销售数据的数据,我们研究了发育迟缓和超重/肥胖患病率的变化,以及UPF消费趋势的最新数据。结果:儿童和母亲的超重/肥胖患病率迅速上升,而发育迟缓率下降缓慢。同时,upf的消费量显著增加,特别是在学龄前儿童中。与富裕家庭相比,贫困家庭超重和肥胖患病率的增长速度越来越快。研究结果强调了婴幼儿对不健康随意食物的早期社会化,包括upf,可能为长期饮食偏好奠定基础,偏好高糖或过量钠的食物。结论:迫切需要解决婴幼儿UPF消费快速增长的问题。备选方案包括扩大世卫组织《营销守则》,以保护0-3岁儿童;针对0-3岁儿童的产品,在包装正面贴上警告标签,以去除所有添加糖,并限制他们消费的食品和饮料中的钠含量。
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引用次数: 0
Associations of 24-h movement behaviour with overweight and obesity among school-aged children and adolescents in Pakistan: An empirical cross-sectional study 巴基斯坦学龄儿童和青少年24小时运动行为与超重和肥胖的关联:一项实证横断面研究。
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-02-23 DOI: 10.1111/ijpo.13208
Moazzam Tanveer, Yujun Cai, Georgian Badicu, Ejaz Asghar, Alexios Batrakoulis, Luca Paolo Ardigò, Serge Brand
<div> <section> <h3> Background</h3> <p>Overweight and obesity among children and adolescents poses a significant public health challenge. In Pakistan, the prevalence of childhood overweight and obesity continues to rise, leading to long-term adverse effects on health. Various external influences shape children's health behaviours and outcomes, with parents, peers, schools, and communities playing crucial roles, particularly during formative years.</p> </section> <section> <h3> Objectives</h3> <p>This cross-sectional study aimed to investigate the associations between 24-h movement behaviour and overweight/obesity among school-aged children and adolescents, focusing on the intrapersonal, interpersonal, community, and school levels from a Social-Ecological Perspective.</p> </section> <section> <h3> Methods</h3> <p>A population-based cross-sectional study was conducted from 15 January to 15 March 2023, using a representative multistage random cluster sampling method. The study enrolled 4200 participants aged 9–17 years and 3371 parents from 62 schools in central Punjab, Pakistan. Participants' body mass index (BMI) was classified based on CDC US 2000 BMI percentiles. Socio-ecological factors were analyzed using chi-square tests, binary logistic regression, and stepwise logistic regression to examine their associations with overweight and obesity.</p> </section> <section> <h3> Results</h3> <p>The results of this study revealed that boys had 18.7% overweight and 9% obesity, while girls had 20.5% overweight and 13.2% obesity. Gender exhibited a significant association with weight status. A considerable proportion of participants did not meet recommended guidelines for junk food consumption (31.5% boys, 33.3% girls), physical activity (70% boys, 83.8% girls), screen time (37.7% boys, 41.1% girls), and sleep (55.7% boys, 54% girls). Individuals engaging in certain 24-h movement behaviours exhibited higher odds of obesity. Specifically, consuming fast food three or more days per week was associated with higher odds of obesity (odds ratio: 9.95, <i>p</i> < 0.01). Engaging in physical activity for less than 60 min per day, twice a week or less, was associated with higher odds of obesity (odds ratio: 3.47, <i>p</i> < 0.01). Spending three or more hours per day on screen time was linked to higher odds of obesity (odds ratio: 2.50, <i>p</i> < 0.01). Furthermore, being a short sleeper was associated with higher odds of overweight (odds ratio: 3.54, <i>p</i> < 0.01).</p> </section> <section> <h3> Conclusions</h3> <p>Children failing to meet none or only
背景:儿童和青少年超重和肥胖是一个重大的公共卫生挑战。在巴基斯坦,儿童超重和肥胖的流行率继续上升,对健康造成长期不利影响。各种外部影响塑造了儿童的健康行为和结果,父母、同伴、学校和社区发挥着关键作用,特别是在成长期。目的:本横断面研究旨在从社会生态学角度探讨学龄儿童和青少年24小时运动行为与超重/肥胖之间的关系,重点关注个人、人际、社区和学校层面。方法:采用有代表性的多阶段随机整群抽样方法,于2023年1月15日至3月15日进行以人群为基础的横断面研究。该研究招募了来自巴基斯坦旁遮普省中部62所学校的4200名9-17岁的参与者和3371名家长。参与者的身体质量指数(BMI)根据美国疾病控制与预防中心2000年BMI百分位数进行分类。采用卡方检验、二元逻辑回归和逐步逻辑回归分析社会生态因素与超重和肥胖的关系。结果:本次研究结果显示,男生超重18.7%,肥胖9%,女生超重20.5%,肥胖13.2%。性别表现出与体重状况的显著关联。相当大比例的参与者在垃圾食品消费(31.5%的男孩,33.3%的女孩)、体育活动(70%的男孩,83.8%的女孩)、屏幕时间(37.7%的男孩,41.1%的女孩)和睡眠(55.7%的男孩,54%的女孩)方面没有达到建议的标准。从事某些24小时运动行为的个体显示出更高的肥胖几率。具体来说,每周吃三天或更多的快餐与更高的肥胖几率相关(优势比:9.95,p)。结论:与满足所有建议的儿童相比,不符合任何一项或仅符合一项指南的儿童超重/肥胖风险增加。个人层面的因素,如饮食习惯、身体活动、久坐行为、睡眠模式和不健康的生活方式选择,对体重状况有显著影响。需要采取紧急干预措施,增加学校的体育教育资源和体育设施,以创造更健康的环境,减少学生中超重/肥胖的患病率,促进终生的体育活动习惯,改善健康和福祉。
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引用次数: 0
Recent prevalence and trends of obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) among US adolescents: 1999 to 2020 美国青少年肥胖症和代谢功能障碍相关脂肪变性肝病(MASLD)的近期流行趋势:1999年至2020年
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-02-19 DOI: 10.1111/ijpo.70003
Michael Sun, Hongbing Sun

Background

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is understudied among US adolescents despite rising obesity rates.

Methods

This study analysed the prevalence and trends of obesity and MASLD among US adolescents aged 12–17 using data from the National Health and Nutrition Examination Survey (NHANES). We developed a new screening model utilizing FibroScan-measured controlled attenuation parameter (CAP) scores, body measurements and blood chemistry data from 2017 to 2020 to assist in analysing MASLD trends from 1999 to 2020.

Results

Between 2017 and 2020, the prevalence of obesity and MASLD was approximately 20%, with about 70% of obese adolescents affected by MASLD. The condition was more common in boys, particularly among Mexican American adolescents. Additionally, 97.2% of those with NAFLD also had MASLD. Adolescents with MASLD had significantly higher body weight, waist circumference, triglyceride levels and alanine transaminase (ALT) levels, along with lower high-density lipoprotein (HDL) cholesterol and an increased risk of liver fibrosis. Insufficient physical activity and poor diet quality were key risk factors for developing MASLD. From 1999 to 2020, the prevalence of MASLD rose significantly, paralleling the increasing rates of obesity.

Conclusions

The study underscores the pressing need to screen at-risk adolescents for metabolic issues associated with steatotic liver diseases, given the rising obesity rates among adolescents. The high overlap between MASLD and NAFLD diagnoses indicates that the transition from NAFLD to MASLD can be effectively integrated into paediatric practice.

背景:代谢功能障碍相关脂肪性肝病(MASLD),以前称为非酒精性脂肪性肝病(NAFLD),在美国青少年中研究不足,尽管肥胖率上升。方法:本研究利用美国国家健康与营养调查(NHANES)的数据,分析了美国12-17岁青少年肥胖和MASLD的患病率和趋势。我们开发了一种新的筛选模型,利用纤维扫描测量的控制衰减参数(CAP)评分、2017年至2020年的身体测量和血液化学数据,帮助分析1999年至2020年的MASLD趋势。结果:2017 - 2020年,肥胖和MASLD患病率约为20%,其中约70%的肥胖青少年受MASLD影响。这种情况在男孩中更为常见,尤其是在墨西哥裔美国青少年中。此外,97.2%的NAFLD患者同时患有MASLD。患有MASLD的青少年体重、腰围、甘油三酯水平和丙氨酸转氨酶(ALT)水平明显较高,高密度脂蛋白(HDL)胆固醇较低,肝纤维化风险增加。运动不足和饮食质量差是发生MASLD的主要危险因素。从1999年到2020年,MASLD的患病率显著上升,与肥胖率的上升同步。结论:鉴于青少年肥胖率的上升,该研究强调了筛查与脂肪变性肝病相关的代谢问题的迫切需要。MASLD和NAFLD诊断之间的高度重叠表明,从NAFLD到MASLD的转变可以有效地融入儿科实践。
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引用次数: 0
Weight development in children with obesity without treatment: A Danish cohort study with long-term follow-up 未经治疗的肥胖儿童体重发展:一项丹麦长期随访队列研究。
IF 2.7 3区 医学 Q1 PEDIATRICS Pub Date : 2025-02-04 DOI: 10.1111/ijpo.70001
Rasmus Møller Jørgensen, Jens Meldgaard Bruun, Mette Fogh, Iris Iglesia Altaba, Luis A. Moreno, Henrik Støvring, Jane Nautrup Østergaard

Introduction

Limited insight exists into the weight development in children with obesity not receiving obesity treatment.

Methods

This cohort study included 467 Danish children aged 5–10 years with obesity (iso-BMI >30 kg/m2) not receiving treatment. Data from mandatory health check-ups on school-children's height and weight (converted to BMI z-scores) were merged with the Danish National Registries. A multivariable logistic regression weighted for the duration of follow-up was used to estimate odds ratios (OR) for normalization of BMI (iso-BMI 18.5–25 kg/m2) and obesity remission (iso-BMI 18.5–30 kg/m2).

Results

During a median follow-up of more than 6 years, 7.9% of the children normalized their BMI, while 45.4% obtained obesity remission. BMI z-score at inclusion acted as a strong inverse predictor for normalizing BMI (OR 0.14 per one-unit SD, CI: 0.03–0.53) and for obesity remission (OR 0.17 per one-unit SD, CI: 0.08–0.37). No other significant predictors were observed in the weighted multivariable models.

Conclusion

Higher BMI z-scores inversely predict normalizing BMI and achieving obesity remission in untreated children. Given that many children naturally achieve obesity remission or weight normalization, resources should focus on understanding barriers of obesity maintenance and to develop effective strategies for those who do not experience improvement.

对未接受肥胖治疗的肥胖儿童体重发展的了解有限。方法:该队列研究纳入467名5-10岁未接受治疗的丹麦肥胖儿童(iso-BMI >30 kg/m2)。强制性健康检查的学龄儿童身高和体重数据(转换为BMI z分数)与丹麦国家登记处合并。采用随访时间加权的多变量logistic回归来估计BMI正常化(iso-BMI 18.5-25 kg/m2)和肥胖缓解(iso-BMI 18.5-30 kg/m2)的比值比(OR)。结果:在中位超过6年的随访期间,7.9%的儿童BMI恢复正常,45.4%的儿童肥胖得到缓解。纳入时的BMI z评分是BMI正常化(OR 0.14 /单位SD, CI: 0.03-0.53)和肥胖缓解(OR 0.17 /单位SD, CI: 0.08-0.37)的一个强有力的反向预测因子。在加权多变量模型中没有观察到其他显著的预测因子。结论:较高的BMI z分数与未治疗儿童BMI正常化和肥胖缓解呈负相关。鉴于许多儿童自然达到肥胖缓解或体重正常化,资源应该集中在了解肥胖维持的障碍,并为那些没有经历改善的儿童制定有效的策略。
{"title":"Weight development in children with obesity without treatment: A Danish cohort study with long-term follow-up","authors":"Rasmus Møller Jørgensen,&nbsp;Jens Meldgaard Bruun,&nbsp;Mette Fogh,&nbsp;Iris Iglesia Altaba,&nbsp;Luis A. Moreno,&nbsp;Henrik Støvring,&nbsp;Jane Nautrup Østergaard","doi":"10.1111/ijpo.70001","DOIUrl":"10.1111/ijpo.70001","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Limited insight exists into the weight development in children with obesity not receiving obesity treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cohort study included 467 Danish children aged 5–10 years with obesity (iso-BMI &gt;30 kg/m<sup>2</sup>) not receiving treatment. Data from mandatory health check-ups on school-children's height and weight (converted to BMI <i>z</i>-scores) were merged with the Danish National Registries. A multivariable logistic regression weighted for the duration of follow-up was used to estimate odds ratios (OR) for normalization of BMI (iso-BMI 18.5–25 kg/m<sup>2</sup>) and obesity remission (iso-BMI 18.5–30 kg/m<sup>2</sup>).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>During a median follow-up of more than 6 years, 7.9% of the children normalized their BMI, while 45.4% obtained obesity remission. BMI <i>z</i>-score at inclusion acted as a strong inverse predictor for normalizing BMI (OR 0.14 per one-unit SD, CI: 0.03–0.53) and for obesity remission (OR 0.17 per one-unit SD, CI: 0.08–0.37). No other significant predictors were observed in the weighted multivariable models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Higher BMI <i>z</i>-scores inversely predict normalizing BMI and achieving obesity remission in untreated children. Given that many children naturally achieve obesity remission or weight normalization, resources should focus on understanding barriers of obesity maintenance and to develop effective strategies for those who do not experience improvement.</p>\u0000 </section>\u0000 </div>","PeriodicalId":217,"journal":{"name":"Pediatric Obesity","volume":"20 5","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijpo.70001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Pediatric Obesity
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