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Gadolinium Distribution in the Kidney, Liver, and Heart of Wistar Rats after Administration of Gadolinium-Based Contrast Agents 钆造影剂对Wistar大鼠肾、肝、心分布的影响
Pub Date : 2022-10-29 DOI: 10.21522/tijar.2014.09.04.art010
Oluwafemi Olumide Egbeyemi
Magnetic resonance imaging (MRI) is an established non-invasive and non-destructive medical imaging modality for the assessment of various organ systems in the human body. Gadolinium-Based Contrast Agent (GBCA) enhanced and improved images from MRI and was believed to be entirely excreted through urine in normal kidney function within 24 hours after injection. Previous studies identified gadolinium accumulations in the brain, bones, and skin of animals. This study evaluated gadolinium retention in normal kidneys, Liver, and heart of Wistar rats after administration of GBCAs in male Wistar rats. Twenty-five male Wistar rats of ages ≥ 5 weeks or ≤ 6 weeks in 4 experimental and 1 control groups were studied. Ethical considerations were obtained from the Institutional Review Board (IRB) of the Nigerian Institute of Medical Research (NIMR), Nigeria. Samples in experimental groups each administered 2.5 mls of 4 different GBCAs, and the control group same per day of saline intravenously through the lateral tail for five days a week and continued for 4 weeks. The kidney, Liver, and Heart tissues of these samples were harvested 4 weeks after the last injection and sent for spectrometry evaluation. Samples in the control group had no gadolinium accumulation. Groups administered gadopentetate dimeglumine, and gadodiamide had greater cardiac metrics (0.397 and 0.390). The higher renal metric was experienced by samples that received dotarem and cyclolux (0.397 and 0.377), though the sample exposed to cyclolux reported more Liver metric (0.407) than other concentrations. Wistar rats’ Kidneys, Liver, and Heart retained gadolinium weeks after injection of GBCAs. Keywords: Dotarem and Cyclolux, Gadolinium, Gadodiamide, Gadopentetate dimenglumine, Magnetic resonance imaging.
磁共振成像(MRI)是一种成熟的非侵入性和非破坏性的医学成像方式,用于评估人体各器官系统。钆基造影剂(GBCA)增强和改善MRI图像,并被认为在注射后24小时内完全通过尿液排出正常肾功能。先前的研究发现钆在动物的大脑、骨骼和皮肤中都有积累。本研究评估了雄性Wistar大鼠给予gbca后,正常肾脏、肝脏和心脏中的钆潴留。选取≥5周龄或≤6周龄雄性Wistar大鼠25只,分为4个实验组和1个对照组。伦理考虑从尼日利亚医学研究所(NIMR)的机构审查委员会(IRB)获得。实验组各给予4种不同的gbca 2.5 ml,对照组每天给予相同的生理盐水,通过侧尾静脉注射,每周5天,持续4周。这些样品的肾、肝和心脏组织在最后一次注射后4周采集,并送去进行光谱分析。对照组样品无钆积累。加多二胺组和加多二胺组的心脏指标更高(0.397和0.390)。接受多他仑和环曲乐的样本的肾脏指标较高(0.397和0.377),但暴露于环曲乐的样本报告的肝脏指标(0.407)高于其他浓度的样本。注射gbca后,Wistar大鼠的肾脏、肝脏和心脏仍保留钆。关键词:Dotarem和Cyclolux,钆,钆二胺,钆二胺,钆二胺,磁共振成像
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引用次数: 0
Making the Law Work for Human Resources for Health (HRH) Training in Zambia 使法律适用于赞比亚的卫生人力资源培训
Pub Date : 2022-10-29 DOI: 10.21522/tijar.2014.09.04.art008
Mabvuto Katwizi Kango
There are several institutions in Zambia that play an important role in regulating the quality of higher education, including Human Resources for Health (HRH) training. However, there were reports of overlaps in the legal mandates of these institutions. In 2021, one of the institutions, the Higher Education Authority (HEA), responded to this challenge by successfully facilitating the amendment of the laws that regulated the quality of higher education. This research investigated whether the amended laws were still suitable enough to ensure quality in higher education and in HRH training. Keywords: Actors, HRH, Law, Regulators, Training, Quality.
赞比亚有几所机构在规范高等教育质量,包括卫生人力资源培训方面发挥着重要作用。但是,有报告说,这些机构的法律任务有重叠。2021年,其中一个机构——高等教育局(HEA)成功地促进了规范高等教育质量的法律的修订,从而应对了这一挑战。本研究调查了修订后的法律是否仍然足以确保高等教育和人力资源培训的质量。关键词:演员、人力资源、法律、监管机构、培训、质量。
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引用次数: 0
An Exploration of the Quality Assurance Roles of the Various Regulators of Human Resources for Health Training in Zambia 探讨赞比亚卫生培训人力资源各监管机构的质量保证作用
Pub Date : 2022-10-29 DOI: 10.21522/tijar.2014.09.04.art001
Mabvuto Katwizi Kango
This inquiry was conducted following reports that questioned the quality of higher education in Zambia, including the quality of Human Resources for Health (HRH) training. One of the notable reports was from research conducted by the Zambia Medical Association (2019). This inquiry built on all these reports by focusing on the roles of the various regulators (also referred to here as Actors) on how their individual and collective roles can play a role in improving the quality of HRH training in Zambia. Ideally, one does not expect to see any challenges in the quality of HRH training because when reading the acts and mandates of the various actors (summarized in Table 1), such as HPCZ, HEA, ZAQA, and local government authorities, there appears to enough authority to provide quality assurance. The inquiry focused on what could have gone wrong and what could have been improved. Keywords: Actors, Human Resources for Health (HRH), Intersectoral collaboration, Quality, Regulators, Training.
在进行这项调查之前,有报告质疑赞比亚高等教育的质量,包括卫生人力资源培训的质量。其中一份值得注意的报告来自赞比亚医学协会(2019年)的研究。这项调查以所有这些报告为基础,重点关注各种监管机构(这里也称为行动者)的角色,以及他们的个人和集体角色如何在提高赞比亚人力资源管理培训质量方面发挥作用。理想情况下,人们不会期望在人力资源培训的质量方面看到任何挑战,因为在阅读各种参与者(如HPCZ、HEA、ZAQA和地方政府当局)的行为和命令时,似乎有足够的权威来提供质量保证。调查的重点是哪些地方可能出错,哪些地方可以改进。关键词:行为人,卫生人力资源,跨部门协作,质量,监管机构,培训
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引用次数: 0
Access to Finance: The Determinants and Limitations to the Supply Side of Finance for Liberia’s Rural Market 融资渠道:利比里亚农村市场融资供给侧的决定因素与限制
Pub Date : 2022-10-29 DOI: 10.21522/tijar.2014.09.04.art006
Andy Saye Gbatu
This critical piece of research paper reviews the literature on the key determinants of finance for Liberia’s rural market. It also takes into account the limitations of the supply of finance for the rural market of Liberia, with the unabated need for the diversification of the Liberian economy in the face of intermittent shocks in the global economy. The study unearthed that investment in agricultural small and medium-sized enterprises (SMEs) will prove adequate in triggering sustainable economic growth and development through poverty alleviation, job creation, and food security which are the drivers of the supply of finance for rural dwellers in Liberia. Notwithstanding, the study found that the supply of finance for Liberian agricultural SMEs is constrained by the lack of creditworthiness information, weak judicial enforcement of contracts and corporate transparency, land ownership, high non-performing loans, and financial literacy. The keywords used in this article include gross domestic product, small and medium-sized enterprises, non-performing loans, inflation, credit rating, bankruptcy, value chain, urbanization, food security, human capital, and risk aversion. Keywords: Bankruptcy, Credit rating, Human capital, Inflation, Small and medium-sized enterprises, Value chain.
这篇重要的研究论文回顾了有关利比里亚农村市场融资关键决定因素的文献。它还考虑到利比里亚农村市场的资金供应有限,面对全球经济的间歇性冲击,利比里亚经济多样化的需要丝毫没有减弱。研究发现,对农业中小企业(SMEs)的投资将被证明足以通过减轻贫困、创造就业机会和粮食安全来引发可持续的经济增长和发展,这些都是利比里亚农村居民融资的驱动因素。尽管如此,该研究发现,利比里亚农业中小企业的融资供应受到缺乏信誉信息、合同和公司透明度的司法执行不力、土地所有权、高不良贷款和金融知识的限制。本文使用的关键词包括国内生产总值、中小企业、不良贷款、通货膨胀、信用评级、破产、价值链、城市化、粮食安全、人力资本、风险规避。关键词:破产,信用评级,人力资本,通货膨胀,中小企业,价值链
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引用次数: 0
Attitudes and Intentions of Health Personnel towards Covid-19 Vaccination in Kaziba Health Zone Kaziba卫生区卫生人员对Covid-19疫苗接种的态度和意图
Pub Date : 2022-10-29 DOI: 10.21522/tijar.2014.09.04.art013
Bontango Kweme Frederic
Introduction: SARS-CoV-2 is a virus of the coronavidae family and of the beta coronavirus group, such as those responsible for SARS and MERS. This Covid-19 is more contagious than SARS and MERS but with a lower death rate. Covid-19 vaccine is a pharmaceutical tool to control the transmission of Covid-19 among the health personnel and the general population. The acceptance of Covid-19 vaccination remains reluctant among the health personnel. The purposes of this study are to determine the intentions and attitudes of health personnel vis-à-vis to Covid-19 vaccination and, to determine the reasons for accepting and refusing Covid-19 vaccination among health personnel in Kaziba Health Zone from 15 to 28 July 2021. Material and methods: our study was descriptive retrospective cross-sectional study. A random sampling method was carried out to collect the data through survey questionnaire with 102 health personnel. The data was analyzed with SPSS and Chi-square test was carried out. Results: the intentions and attitudes of the health personnel vis-à-vis to Covid-19 vaccination was (31.4%), and the participants who declared the mandatory Covid-19 vaccination was 31.4%. The health personnel who accepted the covid-19 vaccine were 21.6%, however, those who refused was 45.1%. Conclusion: health personnel do not have acceptable intentions and attitudes towards Covid-19 vaccination. Only nurses and midwives, physicians and healthcare assistance staff were agreeable to Covid-19 vaccination to control the pandemic. Lack of information was the main refusal reason for Covid-19 vaccination. The health personnel were not willingly too mandatory Covid-19 vaccination. Keywords: Attitudes, Covid-19, Health personnel, Intentions, Kaziba, SARS-CoV-2, Vaccination.
简介:SARS- cov -2是冠状病毒科和β冠状病毒组的一种病毒,与导致SARS和MERS的病毒相同。这种新型冠状病毒比SARS和MERS更具传染性,但死亡率较低。Covid-19疫苗是控制Covid-19在卫生人员和一般人群中传播的药物工具。卫生人员仍然不愿意接受Covid-19疫苗接种。本研究的目的是确定卫生人员对-à-vis接种Covid-19疫苗的意向和态度,并确定2021年7月15日至28日Kaziba卫生区卫生人员接受和拒绝接种Covid-19疫苗的原因。材料和方法:本研究为描述性回顾性横断面研究。采用随机抽样的方法,对102名卫生工作人员进行问卷调查。数据采用SPSS统计软件进行分析,采用卡方检验。结果:卫生人员对-à-vis新冠肺炎疫苗接种的意向和态度为(31.4%),申报强制接种新冠肺炎疫苗的参与者为31.4%。接受新冠肺炎疫苗的卫生人员占21.6%,拒绝接种的卫生人员占45.1%。结论:卫生人员对Covid-19疫苗接种的意向和态度不可接受。只有护士、助产士、医生和医疗辅助人员同意接种Covid-19疫苗以控制大流行。缺乏信息是拒绝接种Covid-19疫苗的主要原因。卫生人员不太愿意强制接种Covid-19疫苗。关键词:态度,Covid-19,卫生人员,意向,Kaziba, SARS-CoV-2,疫苗接种
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引用次数: 0
Access to Finance: Determinants and Limitations to the Demand Side of Finance for Liberia’s Rural Market 融资渠道:利比里亚农村市场融资需求方的决定因素与限制
Pub Date : 2022-10-29 DOI: 10.21522/tijar.2014.09.04.art014
Andy Saye Gbatu
This study reviews the theoretical literature regarding determinants and the limitations to the demand side of rural finance in Liberia with the coming into effect of the National Financial Inclusion Strategy (NFIS). The outcome of this study reveals that education, income level, household assets, and agriculture rank as the outstanding drivers of the demand for finance in Liberia’s rural market. Obviously, the demand for financial services in the rural market of Liberia is very high. However, the demand is limited by a litany of factors such as slow economic growth & lack of job opportunities, poor public infrastructure, structural unemployment, few diversification opportunities, seasonality in agriculture, imperfect information & supervision, and poor social protection and market failures. The keywords used by the author in this article encompass creditworthiness, information asymmetry, financial inclusion, Pareto efficiency, poverty alleviation, and rural finance. Keywords: Credit worthiness, Financial inclusion, Information asymmetry, Pareto efficiency, Poverty alleviation, Rural finance.
本研究回顾了国家普惠金融战略(NFIS)生效后利比里亚农村金融需求侧的决定因素和限制的理论文献。这项研究的结果表明,教育、收入水平、家庭资产和农业是利比里亚农村市场融资需求的主要驱动因素。显然,利比里亚农村市场对金融服务的需求非常高。然而,需求受到一系列因素的限制,如经济增长缓慢和缺乏就业机会、公共基础设施薄弱、结构性失业、多样化机会少、农业季节性、信息和监管不完善、社会保护不力和市场失灵。本文作者使用的关键词包括信誉度、信息不对称、普惠金融、帕累托效率、扶贫和农村金融。关键词:信用度,普惠金融,信息不对称,帕累托效率,扶贫,农村金融
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引用次数: 0
The Influence of Media on Voting Behavior in Ghana: The Case in Western North Region 加纳媒体对投票行为的影响:以西部北部地区为例
Pub Date : 2022-07-30 DOI: 10.21522/tijar.2014.09.03.art005
I. Damptey
The media have strong impact on Ghanaians’ voting decisions. Parties in multiple democracies have since harnessed the use of the media in our political process. The objective of the study was to investigate how the media influence voting behavior in the Western North Region of Ghana. In this study, Purposive and convenience sampling techniques were used. The study adopted qualitative and quantitative research designs. Questionnaires and interview guides were used to collect data. A sample size of 404 respondents was studied. The study revealed that voters in the study area have access to communication devices for obtaining information through political campaigns, advertisements on broadcast, social, print, support, and transit media, which all have a significant impact on voting behavior in the study Region. The study revealed that 65.6% of those polled said the media had a major influence on their voting behavior in the 2020 general elections in the research Region. The study also revealed that party affiliation, party manifesto, current economic conditions, family and friends, and current government performance were other factors that influenced voting behavior in the study area apart from the media. The study, therefore, suggested that the technical infrastructure of the media in the study Region be expanded since voters demand increased and improved access to and usage of the media to get information on political parties’ operations in order to shape their voting behavior. Also, media sanity should be strengthened in the study Region.
媒体对加纳人的投票决定有很大的影响。此后,多个民主国家的政党在我们的政治进程中利用媒体。本研究的目的是调查媒体如何影响加纳西北地区的投票行为。本研究采用目的性和便捷性抽样技术。本研究采用定性和定量研究设计。采用问卷调查和访谈指南收集数据。我们对404名受访者进行了研究。研究表明,研究地区的选民可以通过政治竞选、广播、社交、印刷、支持和运输媒体上的广告获取信息,这些都对研究地区的投票行为产生了重大影响。该研究显示,在研究地区,65.6%的受访者认为媒体对2020年议会选举的投票行为产生了重大影响。研究还发现,除了媒体外,党派关系、政党宣言、当前经济状况、家庭和朋友以及当前政府绩效是影响研究区域投票行为的其他因素。因此,这项研究建议扩大研究区域内新闻媒介的技术基础结构,因为选民要求增加和改善接触和使用新闻媒介的机会,以便获得关于政党运作的信息,从而影响他们的投票行为。此外,还应加强研究地区的媒体理智。
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引用次数: 0
An Assessment of Healthcare Relationship Trust between Patent Medicine Vendors and Residents of Hard-to-Reach Settlements in Northern Nigeria 尼日利亚北部难以到达定居点的专利药品供应商和居民之间的医疗保健关系信任评估
Pub Date : 2022-07-30 DOI: 10.21522/tijar.2014.09.03.art006
Oluwasegun John Ibitoye
A trusting relationship is required for effective communication between care providers and care seekers, and trust is a determinant of early healthcare-seeking and care outcomes. The patient-Doctor healthcare trust relationship has been widely studied in different settings. However, there is a dearth of information on whether the factors underlying healthcare relationship trust between patients and their doctors are the same as those underlying patients’ trust in other healthcare professionals (including the PPMVs). This study, therefore, aims to assess the level and determinants of healthcare relationship trust between patent medicine vendors and their clients in hard-to-reach settlements in North-western Nigeria. We adapted the revised healthcare relationship trust scale, administered by trained data collectors using android devices. The data were analysed using Stata (version 16). We used the Chi-square test to identify the correlates of the level of trust(high/low), and binary logistic regression was used to identify its determinants. Statistical significance was defined as P<0.05. Slightly above one-quarter (28.1%) of the underserved had high healthcare relationship trust in the PPMVs. Being married, male, residing in a rented or makeshift shelter in Kaduna state, with under-five child(ren) in their household, and self-reporting good health predicted a high level of healthcare relationship trust in PPMVs among the underserved who participated in this study. We concluded that the personal and household characteristics of the underserved could significantly influence their level of trust in PPMV. Therefore, to achieve the aim of improving health outcomes in deprived populations, initiatives seeking to integrate PPMVs into the formal health system in resource-constrained settings should seek to address the determinants of healthcare relationship trust in these populations as part of their rollout process. Keywords: Communities, Hard-to-reach, Healthcare, Trust, Relationship, Workforce.
信任关系是护理提供者和求助者之间有效沟通所必需的,信任是早期医疗保健寻求和护理结果的决定因素。医患医疗信任关系在不同情境下被广泛研究。然而,关于患者与医生之间医疗关系信任的潜在因素是否与患者对其他医疗专业人员(包括ppmv)的潜在信任相同的信息缺乏。因此,本研究旨在评估尼日利亚西北部难以到达定居点的专利药品供应商及其客户之间医疗关系信任的水平和决定因素。我们采用了修订后的医疗关系信任量表,由训练有素的数据收集人员使用android设备进行管理。使用Stata(版本16)对数据进行分析。我们使用卡方检验来确定信任水平的相关因素(高/低),并使用二元逻辑回归来确定其决定因素。P<0.05为差异有统计学意义。略高于四分之一(28.1%)服务不足的人对ppmv有很高的医疗关系信任。已婚、男性、居住在卡杜纳州租用或临时住所、家中有五岁以下儿童、自我报告健康状况良好,这预示着参与本研究的服务不足者对PPMVs的医疗保健关系的高度信任。我们的结论是,服务不足者的个人和家庭特征会显著影响他们对PPMV的信任水平。因此,为了实现改善贫困人群健康结果的目标,在资源有限的环境中,寻求将ppmv纳入正式卫生系统的倡议应寻求解决这些人群中卫生保健关系信任的决定因素,作为其推广过程的一部分。关键词:社区,难以触及,医疗保健,信任,关系,劳动力。
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引用次数: 0
Evaluating the Implementation of Components of the Performance Management System in the Zambian Public Service: A Case Study of Development Bank of Zambia 评价赞比亚公共服务部门绩效管理体系各组成部分的实施情况:以赞比亚开发银行为例
Pub Date : 2022-07-30 DOI: 10.21522/tijar.2014.09.03.art014
C. Banda
The Government of the Republic of Zambia has been undertaking public sector reforms beginning with Ministries and cascading to State Owned Enterprises such as the Development Bank of Zambia whose main thrust has been to improve service delivery by introducing performance management systems. The Bank has been implementing performance management systems since 2015. Despite these efforts, the Zambian public service is considered inefficient in its quest to deliver services. This study was conducted at Development Bank of Zambia in Lusaka, Zambia. Therefore, the aim of the study was to Evaluate the Implementation of Components of the Performance Management System in the Zambian Public Service: A Case of the Development Bank of Zambia. The study also sought to determine the origins of the concept performance management, define the concept, describe the approaches to performance management, the nature and content of a performance management system, outline the steps to be followed in developing a performance management system, identify the objectives and benefits of implementing the performance management system, identify the general problems associated with the implementation of the performance management system and make recommendations on how to improve the implementation of performance management and suggest areas for further research. Keywords: Public Sector Reforms, Performance Management System, Service Delivery, Zambia.
赞比亚共和国政府一直在进行公共部门改革,从各部委开始,逐步扩展到赞比亚开发银行等国有企业,其主要目的是通过引进业绩管理制度来改善服务的提供。自2015年以来,世行一直在实施绩效管理体系。尽管做出了这些努力,赞比亚的公共服务在提供服务方面被认为效率低下。这项研究是在赞比亚卢萨卡的赞比亚开发银行进行的。因此,本研究的目的是评估赞比亚公共服务部门绩效管理系统组成部分的实施情况:以赞比亚开发银行为例。这项研究还试图确定业绩管理概念的起源,定义这个概念,描述业绩管理的方法,业绩管理制度的性质和内容,概述在制订业绩管理制度时应遵循的步骤,确定执行业绩管理制度的目标和好处。找出与推行绩效管理系统有关的一般问题,并就如何改善绩效管理的推行提出建议,并提出进一步研究的范畴。关键词:公共部门改革,绩效管理体系,服务提供,赞比亚
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引用次数: 0
A Comparison of Students’ Attitude and Perception towards Morning or Afternoon Classes in Texila American University, 2021 德州美国大学学生对上午或下午课程的态度和看法比较,2021
Pub Date : 2022-07-30 DOI: 10.21522/tijar.2014.09.03.art016
Ramona S. Adams
This paper reports on the findings from focus groups conducted at Texila American University on the attitudes of its medical students towards morning lectures. Students felt that two things were vital for a good lecture: (1) that the lecturer goes beyond what is written in the lecture notes; (2) that the lecture is interactive, by which students meant that the lecturer asks if students understand concepts and adjust the delivery accordingly, and the lecturer answers the students’ questions. The students in the focus groups also discussed what makes for a bad lecture: (1) lecturers reading straight from slides; (2) lecturers who ‘blame the students’ by saying that students don’t work hard enough and are too lazy to turn up to lectures; and (3) lecturers who cover the material too slowly or too quickly. The most prominent reason given for not attending lectures was the timetabling of lectures in such a way that students had too few classes in one day to make the sojourn to university worthwhile and relating to feelings of tiredness each afternoon. Any university seeking to improve attendance at lectures should perhaps look as much to improving its timetabling practices as it does to improve the practices of its individual lecturers. Keywords: Focus groups, Lectures, Student attitudes.
本文报告了在Texila美国大学进行的焦点小组对其医学生对上午讲座的态度的调查结果。学生们认为,一场好的讲座有两点至关重要:(1)讲师讲得比课堂讲稿上写的要多;(2)讲座是互动式的,即由讲师询问学生是否理解概念并相应地调整讲课方式,由讲师回答学生提出的问题。焦点小组的学生还讨论了造成糟糕讲座的原因:(1)讲师直接从幻灯片上阅读;(2)老师“责备学生”,说学生学习不够努力,懒得去上课;(3)讲课太慢或太快的讲师。不去上课的最主要的原因是上课的时间安排,学生们一天的课太少,以至于大学的逗留没有意义,而且每天下午都感觉很累。任何想要提高出勤率的大学,或许都应该像改进个别讲师的做法一样,注重改进排课制度。关键词:焦点小组,讲座,学生态度。
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引用次数: 0
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