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evaluation of arrival metaphylaxis with enrofloxacin compared to tulathromycin in feedlot cattle at high risk of developing bovine respiratory disease in Mexico 评价恩诺沙星与图拉霉素在墨西哥发生牛呼吸道疾病高风险的饲养场牛中的到达性过敏反应
Pub Date : 2022-10-19 DOI: 10.21423/bovine-vol56no1p53-59
L. Burciaga-Robles, C. McMullen, A. Bras, Mariana Guerra-Maupome, Rodolfo A. Nava-Gaspar, R. Rademacher, S. Hannon, Victor E. Mercado-Talamantes, C. Booker
  In this large-pen commercial field trial, mixed beef-breed bulls and heifers were randomly allocated at feedlot arrival to 1 of 2 experimental groups: ENRO or TULA. Animals in the ENRO group (10 multi-pen lots; 2037 animals) received a subcutaneous injection of enrofloxacin at a dosage of 3.4 mg/lb (7.5 mg/kg) body weight once at allocation. Animals in the TULA group (10 multi-pen lots; 2036 animals) received a subcutaneous in­jection of tulathromycin at a dosage of 1.1 mg/lb (2.5 mg/kg) body weight once at allocation. Study animals were housed by experimental group in commercial feedlot pens and fol­lowed from allocation until slaughter. There were no statisti­cal differences detected in any of the animal health or feedlot performance outcome variables between the experimental groups at the P < 0.050 level. Given the lack of detectable sta­tistical differences in animal health and feedlot performance outcome variables in the current study, the relative cost effec­tiveness of metaphylaxis programs utilizing enrofloxacin or tulathromycin in mixed beef-breed bulls and heifers at high risk of developing bovine respiratory disease should be depen­dent on the relative cost of each program, as well as any intan­gible attributes such as syringability, storage requirements, potential for antimicrobial resistance, etc.
在本大型猪圈商业大田试验中,在到达饲养场时,将混合牛种公牛和小母牛随机分为2个实验组:ENRO组或TULA组。ENRO组动物(10个多栏;2037只动物在分配时皮下注射恩诺沙星,剂量为3.4 mg/lb (7.5 mg/kg)体重。TULA组动物(10个多栏;2036只动物)在分配时皮下注射图拉霉素,剂量为1.1 mg/lb (2.5 mg/kg)体重。实验动物由试验组饲养在商业饲养场围栏内,从分配到屠宰。各组动物健康和饲养场生产性能指标均无统计学差异(P < 0.050)。鉴于在目前的研究中缺乏可检测到的动物健康和饲养场性能结果变量的统计差异,使用恩诺沙星或图拉霉素对发生牛呼吸道疾病高风险的混合牛种公牛和小母牛进行过敏反应计划的相对成本效益应取决于每个计划的相对成本,以及任何无形属性,如注射性、储存要求、潜在的抗菌素耐药性等。
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引用次数: 0
Comparison of the effect of different management strategies on the quality of recycled sand used for bedding in free stalls in southeastern Pennsylvania 不同管理策略对宾夕法尼亚州东南部自由养殖场床上用再生砂质量影响的比较
Pub Date : 2022-10-19 DOI: 10.21423/bovine-vol56no1p60-68
E. Egolf, M. Kristula, D. Stefanovski
The effect of different management strategies on dry matter (DM), organic matter (OM) and bacterial populations in newly recycled sand (RS) were compared on three commercial dairy farms in southeastern Pennsylvania during late spring and summer. DM increased by 0.98%, OM decreased by 0.05%, and bacterial numbers were not different comparing arranging RS into one windrow and turning 3 times to forming a static pile. RS stored outside had fewer coliform bacteria compared to when stored inside under cover. RS should be stored for a minimum of 22 days before placement back into the cow stalls to minimize the numbers of bacteria associated with mastitis.
在美国宾夕法尼亚州东南部的3个商业奶牛场,比较了不同管理策略对新循环砂(RS)干物质(DM)、有机质(OM)和细菌种群的影响。单窗布置与翻3次形成静桩相比,DM增加0.98%,OM减少0.05%,细菌数量无显著差异。储存在室外的RS与储存在有盖的室内相比,大肠菌群细菌较少。RS在放回牛栏之前应至少存放22天,以尽量减少与乳腺炎相关的细菌数量。
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引用次数: 0
Association of feedlot disease treatments on the probability of heart disease syndrome in U.S. feedlot cattle 饲养场疾病治疗协会对美国饲养场牛心脏病综合征的可能性
Pub Date : 2022-10-19 DOI: 10.21423/bovine-vol56no1p1-13
B. Johnson, D. Amrine, R. Larson, B. White
Data from 14 U.S. feedlots from January 1, 2017, through De­cember 31, 2020, were evaluated for disease treatment on the probability of being terminally diagnosed with heart disease (HD). The study objective was two-fold: 1) determine the as­sociation between the number of bovine respiratory disease (BRD) treatments (0,1,2,3+) and HD, and 2) determine the as­sociation of common feedlot disease treatment (AIP, BRD, Complex Disease, GI+Bloat, Other), and cohort demographics with HD. Data were analyzed using generalized mixed-effects models to evaluate the probability of terminal HD. Covariates of interest include: BRD treatments, feedlot disease category, average cohort arrival weight, arrival year, arrival quarter, feedlot elevation and sex. The number of BRD treatments was associated with HD (P < 0.01). Cattle requiring additional BRD treatments increased their probability of not finishing the feeding period due to HD. The magnitude of this association was influenced by average cohort arrival weight, feedlot eleva­tion, sex and arrival quarter (P < 0.01). Feedlot disease catego­ries were associated with the probability of not finishing the feeding phase due to a HD diagnosis (P < 0.01). The magnitude of this association was influenced by average cohort arrival weight, and feedlot elevation (P < 0.01). Sex was influenced by feedlot elevation on the probability of not finishing due to HD diagnosis (P < 0.01) with higher elevations having a greater probability of HD. The majority of HD cattle were railed prior to death at the feedlot (9 of the 15 per 10,000 cattle received).
从2017年1月1日到2020年12月31日,来自14个美国饲养场的数据被评估为疾病治疗的最终诊断为心脏病(HD)的概率。研究目的有两个:1)确定牛呼吸道疾病(BRD)治疗次数(0,1,2,3+)与HD之间的关系,2)确定常见饲养场疾病治疗(AIP, BRD,复杂疾病,GI+腹胀,其他)与HD的队列人口统计学的关系。使用广义混合效应模型分析数据以评估晚期HD的概率。感兴趣的共变量包括:BRD治疗、饲养场疾病类别、平均队列到达体重、到达年份、到达季度、饲养场海拔和性别。BRD治疗次数与HD相关(P < 0.01)。需要额外BRD治疗的牛增加了因HD而无法完成饲喂期的可能性。这种相关性的大小受平均队列到达体重、饲养场海拔、性别和到达时间的影响(P < 0.01)。饲养场疾病类别与因HD诊断而无法完成饲养期的概率相关(P < 0.01)。这种关联的程度受平均队列到达体重和饲养场海拔的影响(P < 0.01)。性别受饲养场海拔高度的影响,对因HD诊断而不完成的概率有影响(P < 0.01),海拔越高,HD的概率越大。大多数HD牛在死前在饲养场进行了围栏饲养(每接收的15头牛中有9头)。
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引用次数: 2
description of infectious bovine keratoconjunctivitis outbreaks in West Virginia beef herds 西弗吉尼亚州肉牛群中传染性牛角膜结膜炎暴发的描述
Pub Date : 2022-01-03 DOI: 10.21423/bovine-vol55no2p79-88
Caleb H. Glover, A. Woolums, R. Berghaus, Isaiah J. Smith, L. Carlson
Infectious bovine keratoconjunctivitis (IBK) is the most important ocular disease of cattle. Prevention and control of the disease can prove challenging, and the list of potential etiologic agents has expanded in recent years. Little has been recently published characterizing IBK outbreaks at the herd level. This case series investigation was conducted to describe the disease characteristics and management practices in herds affected by IBK outbreaks in 1 practice area in West Virginia in 2019. Seven producers were interviewed: 6 cowcalf producers and 1 stocker producer. Producers were asked questions pertaining to disease severity and management, such as herd health protocols and husbandry. In addition, organisms from each of the herds were identified by culture and/or PCR. Results revealed a range of disease incidence as well as similarities and differences in management practices among herds. The interpretability of results is limited due to small sample size and data collection method; however, results suggest that some herds in the area where producerswere interviewed experienced severe IBK outbreaks, and that some management practices relevant to IBK were similar between herds. Results also suggest that further study to identify poorly characterized IBK risk factors is warranted.
传染性牛角膜结膜炎(IBK)是牛最重要的眼部疾病。预防和控制该疾病可能具有挑战性,近年来潜在病因的清单已经扩大。最近发表的关于IBK在畜群水平暴发特征的文章很少。本研究对2019年西弗吉尼亚州1个实践区受IBK暴发影响的畜群进行了病例系列调查,以描述其疾病特征和管理措施。采访了7个生产者:6个小牛生产者和1个牲畜生产者。向生产者询问了有关疾病严重程度和管理的问题,如畜群卫生协议和畜牧业。此外,通过培养和/或PCR对每个畜群的微生物进行鉴定。结果揭示了畜群之间的疾病发病率范围以及管理实践的异同。由于样本量小和数据收集方法的限制,结果的可解释性有限;然而,结果表明,在接受采访的生产者所在地区的一些畜群经历了严重的IBK暴发,并且与IBK相关的一些管理措施在畜群之间是相似的。结果还表明,进一步研究确定特征不明确的IBK危险因素是有必要的。
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引用次数: 0
Systematic review of vaccine efficacy against Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in North American cattle 北美牛溶血性曼海姆病、多杀性巴氏杆菌和嗜睡组织杆菌疫苗疗效的系统评价
Pub Date : 2021-12-31 DOI: 10.21423/bovine-vol55no2p125-133
S. Capik, H. Moberly, R. Larson
Bovine respiratory disease (BRD) continues to greatly affect beef, dairy, and veal production systems. Vaccination against the bacteria involved is common, yet questions remain regarding efficacy. The purpose of this review was to evaluate the evidence for effects of vaccinating United States or Canadian beef, dairy, or veal calves for Mannheimia haemolytica, Pasteurella multocida, or Histophilus somni on BRD-related morbidity, mortality, or postmortem lung lesions. Comprehensive searches were performed of MEDLINE, EMBASE, and CAB Abstracts via OVID. The Bovine Practitioner and references of relevant systematic reviews were searched by hand. Major commercial vaccine producers were queried for additional product information. Peer-reviewed, published after 1979, full text available in English, performed in the US/Canada, control group included, sufficient evidence of randomization/blinding, and correct statistical methods were essential criteria for inclusion in the review. Five studies met the criteria. Of them, 1 investigated a H. somni and M. haemolytica vaccine in feeder calves, 1 studied M. haemolytica vaccination in feeder calves, 1 evaluated a different commercially available M. haemolytica vaccine and 1 experimental M. haemolytica vaccine in young Holstein calves, and 1 investigated multiple vaccines for P. multocida or M. haemolytica or combinations thereof in nursing beef calves. There are too few repeated studies on comparable populations to support further analysis of BRD bacterial vaccine efficacy in North American cattle.
牛呼吸道疾病(BRD)继续严重影响牛肉、乳制品和小牛肉生产系统。针对相关细菌的疫苗接种是常见的,但关于有效性的问题仍然存在。本综述的目的是评估为美国或加拿大的牛肉、奶制品或小牛肉接种溶血性曼海默病、多杀性巴氏杆菌或索氏组织杆菌对brd相关发病率、死亡率或死后肺部病变的影响。通过OVID对MEDLINE、EMBASE和CAB摘要进行综合检索。手工检索《牛从业者》和相关系统综述的参考文献。向主要商业疫苗生产商询问了其他产品信息。同行评议,1979年以后发表,英文全文,在美国/加拿大进行,包括对照组,充分的随机化/盲法证据和正确的统计方法是纳入本综述的基本标准。5项研究符合标准。其中,1项研究在饲养小牛中调查了一种索氏嗜血杆菌和溶血性支原体疫苗,1项研究在饲养小牛中研究了溶血性支原体疫苗,1项评估了不同的市售溶血性支原体疫苗和1种实验性溶血性支原体疫苗,1项研究了多杀性假单胞杆菌或溶血性支原体的多种疫苗或它们的组合。对可比种群的重复研究太少,不足以支持对北美牛的BRD细菌疫苗效力的进一步分析。
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引用次数: 8
Factors influencing administrative personnel and veterinarian turnover and compensation packages in rural mixed-animal practices over a 5-year period 影响5年农村混合畜牧经营管理人员和兽医更替及补偿方案的因素
Pub Date : 2021-12-31 DOI: 10.21423/bovine-vol55no2p108-114
Gabryelle Gilliam, B. White, C. Dodd
Personnel management is one of the keys to developing and maintaining a successful veterinary practice. The research objective was to identify factors influencing administrative personnel and veterinarian turnover, as well as compensation packages of owners, new associates, and 10-year associates. A web-based questionnaire was sent to AVC and AABP list-serves consisting of approximately 2,007 members; 125 complete responses were received. Multivariable models were created using factors identified as associated with the outcome variables with a significance level of P < 0.05. Lower administrative personnel turnover was associated with the presence of veterinarian retirement plans, asset protection plans, new associate compensation packages, and the number of veterinarians leaving the practice. Lower veterinarian turnover was associated with veterinarian ownership and the number of administrative personnel leaving the practice. Higher owner compensation packages were associated with longer practice establishment, use of marketing plans, and more veterinarian annual vacation days. Higher compensation packages for 10-year associates were associated with the number of administrative personnel, more all-veterinarian and all-staff meetings, fewer veterinarian hours per week, more hiring of administrative personnel, and fewer administrative personnel leaving the practice. Administrative personnel and veterinarian turnover were impacted by business management practices and number of personnel.
人员管理是发展和维持一个成功的兽医实践的关键之一。研究的目的是确定影响管理人员和兽医更替的因素,以及业主、新员工和10年员工的薪酬方案。向AVC和AABP名单服务人员(约2007名成员)发送了一份基于网络的调查问卷;共收到125份完整答复。采用与结果变量相关的因素建立多变量模型,显著性水平为P < 0.05。较低的行政人员流失率与兽医退休计划、资产保护计划、新的助理薪酬方案和离开诊所的兽医人数有关。较低的兽医流动率与兽医所有权和离开诊所的行政人员数量有关。较高的业主补偿方案与较长的实践建立、使用营销计划和更多的兽医年假有关。10年从业人员较高的薪酬方案与行政人员数量、更多的全兽医和全体员工会议、更少的每周兽医工作时间、更多的行政人员雇用以及更少的行政人员离职有关。行政人员和兽医的更替受到企业管理做法和人员数量的影响。
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引用次数: 0
Evaluating the environmental survivability of Mannheimia haemolytica on various potential fomites 溶血性曼海姆病在各种潜在污染物上的环境生存能力评价
Pub Date : 2021-12-31 DOI: 10.21423/bovine-vol55no2p120-124
Robert P. Ruffin, S. Lawhon, B. Lubbers, S. Capik
Bovine respiratory disease (BRD) is an important cause of morbidity and mortality in beef and dairy cattle in North America. Of the significant bacteria implicated in BRD cases, Mannheimia haemolytica is the most common microbe isolated in clinical cases, yet little is known about its environmental survivability. The objective of this study was to examine relative survivability of M. haemolytica on metal, wood, and plastic under varying environmental conditions. Microenvironments were constructed at approximately 37℉ (3℃), 71℉ (22℃), and 97℉ (36℃) using plastic containers and monitored for temperature and humidity. Stainless steel, polypropylene, and wood spheres were inoculated with M. haemolytica, placed in each microenvironment, and cultured for viable bacteria at 0, 2, 6, 24, and 48 h after inoculation. Presence or absence of growth of M. haemolytica was confirmed by MALDI-TOF mass spectrometry. Both wood and plastic materials supported the recovery of viable bacteria for a much longer duration than stainless steel. Additionally, increased temperature and decreased humidity lowered bacterial viability. These results demonstrate that both material and environment are factors related to M. haemolytica survival, which has potential biosecurity implications when managing BRD in beef and dairy operations.
牛呼吸道疾病(BRD)是北美肉牛和奶牛发病和死亡的重要原因。在与BRD病例有关的重要细菌中,溶血性曼海姆菌是临床病例中分离到的最常见的微生物,但对其环境存活率知之甚少。本研究的目的是研究溶血分枝杆菌在不同环境条件下对金属、木材和塑料的相对存活率。使用塑料容器在大约37℉(3℃)、71℉(22℃)和97℉(36℃)下构建微环境,并监测温度和湿度。将不锈钢球、聚丙烯球和木球分别接种溶血支原体,置于每个微环境中,接种后0、2、6、24和48 h培养活菌。MALDI-TOF质谱法证实溶血支原体是否生长。木材和塑料材料都支持活菌的恢复比不锈钢长得多的持续时间。此外,温度升高和湿度降低会降低细菌的生存能力。这些结果表明,材料和环境都是与溶血分枝杆菌存活相关的因素,这在管理牛肉和乳制品生产中的BRD时具有潜在的生物安全意义。
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引用次数: 0
Assessment of the evolution of the proportion of respiratory and enteric pathogens and diseases in pre-weaned unvaccinated dairy heifers from Québec, Canada 评估来自加拿大quamesbec未接种疫苗的断奶前奶牛中呼吸道和肠道病原体和疾病比例的演变
Pub Date : 2021-12-31 DOI: 10.21423/bovine-vol55no2p140-152
J. Denis-Robichaud, Marie-Ève Tremblay Cléroux, S. Buczinski, Marie-Lou Gauthier, J. Dubuc, D. Francoz
The objective of this study was to describe the proportion of enteric and respiratory pathogens and diseases in unvaccinated pre-weaned dairy heifers, in their first 2 weeks of life (exam 1), and at 4- to 8-weeks old (exam 2). Heifers from 20 dairy herds were examined and sampled twice for respiratory and enteric pathogens and diseases. Respiratory health score and ultrasonographic lung consolidation were assessed, and nasopharyngeal swabs, blood samples, and feces samples were collected. The prevalence for each disease and pathogen was described, and the difference between exams 1 and 2 was assessed. A total of 198 heifers were included at exam 1, and 182 of them were examined again at exam 2. At exam 1, the prevalence of respiratory diseases (positive clinical score or presence of lung consolidation) and diarrhea was 18% and 23%, respectively. At exam 2, the prevalence of respiratory diseases and diarrhea was 62% and 13%, respectively. Heifers were less likely to have respiratory diseases and pathogens at exam 1 than exam 2, and were more likely to have diarrhea at exam 1 than exam 2. These results help in understanding the dynamic of respiratory and enteric pathogens and diseases.
本研究的目的是描述未接种疫苗的断奶前奶牛中肠道和呼吸道病原体和疾病的比例,在它们生命的头两周(检查1)和4到8周(检查2)。来自20个奶牛群的小母牛进行了两次呼吸道和肠道病原体和疾病的检查和采样。评估呼吸健康评分和超声肺实变,收集鼻咽拭子、血液和粪便样本。描述了每种疾病和病原体的患病率,并评估了检查1和检查2之间的差异。一共有198头小母牛参加了第一次测试,其中182头在第二次测试中再次接受了测试。在检查1时,呼吸道疾病(临床评分阳性或存在肺实变)和腹泻的患病率分别为18%和23%。在检查2时,呼吸道疾病和腹泻的患病率分别为62%和13%。小母牛在第一次检查中患呼吸道疾病和病原体的可能性低于第二次检查,在第一次检查中患腹泻的可能性高于第二次检查。这些结果有助于了解呼吸道和肠道病原体和疾病的动态。
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引用次数: 1
Comparison of frontal-sinus and poll shot locations as secondary methods for euthanizing dairy cattle with a penetrating captive bolt gun 用穿透式螺栓枪对奶牛实施安乐死的次要方法:额窦和轮孔射击位置的比较
Pub Date : 2021-12-31 DOI: 10.21423/bovine-vol55no2p115-119
J. Robbins, Rachel S. Williams, R. Derscheid, Brett Boyum, C. Spangler
Humane euthanasia is a crucial component of dairy farm animal welfare programs. When using either a gunshot or captive bolt, the frontal-sinus area is well established as the primary shot location, but a secondary shot is often used as well. The objective of this study was to evaluate the efficacy of 2 different secondary shot locations. Cattle from a commercial dairy operation (n = 44) were randomly assigned to receive a secondary shot in the frontal-sinus or poll location and clinical signs of consciousness were assessed. A subsample of adult cattle heads (n = 6) were also evaluated to assess the extent of trauma. With the exception of heartbeat, all signs of sensibility were absent immediately following the first frontal-sinus shot and remained absent until confirmation of death, regardless of treatment (P > 0.05). Relatively fewer animals shot in the poll location had a heartbeat 5 min after being shot (P = 0.03). Pathology results on the subsample of adult cattle showed poll shots rarely penetrated beyond the cerebrum and only 1 of 6 animals had a severed brainstem. We conclude the frontal-sinus and poll locations are similarly effective secondary shot locations, and brainstem damage may not be necessary for irreversible insensibility and death.
人道安乐死是奶牛场动物福利项目的重要组成部分。当使用枪法或栓法时,额窦区域被确定为主要射击位置,但也经常使用二次射击。本研究的目的是评估2种不同的二次注射位置的疗效。来自一家商业奶牛场的牛(n = 44)被随机分配在额窦或轮状部位接受二次注射,并评估临床意识体征。还对成年牛头的亚样本(n = 6)进行了评估,以评估创伤的程度。除心跳外,在第一次额窦注射后,所有的敏感性迹象都立即消失,直到确认死亡,无论治疗如何(P > 0.05)。在投票地点射击的动物在射击后5分钟出现心跳的相对较少(P = 0.03)。成年牛亚样本的病理结果显示,枪弹很少穿透大脑,6头牛中只有1头的脑干被切断。我们得出结论,额窦和脑干位置同样是有效的二次注射位置,脑干损伤可能不是不可逆转的麻木和死亡所必需的。
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引用次数: 1
Retrospective evaluation of excess death loss in feedlot cattle associated with in-feed tylosin application programs 回顾性评价超额死亡损失饲养场牛与饲料有关泰乐菌素应用程序
Pub Date : 2021-12-31 DOI: 10.21423/bovine-vol55no2p134-139
S. Rutten-Ramos, S. Simjee, J. L. Bargen, G. Vogel
Daily feedlot records from steer and heifer lots slaughtered between January 2015 and December 2020 were evaluated for timing of tylosin programs and death events. Tylosin applications were described as Any/None (1/0) in the first 30 days-on-feed, Any in the middle feeding period, and Any/None (1/0) in the last 30 days-on-feed. The final analysis included 125,520 lots of cattle with 18,814,224 head placed. By year, week of the year, week on feed, sex type, hundred-weight at placement and tylosin program, weekly deaths were summarized as deaths per thousand head fed (Deaths_K). Using continuously fed tylosin lots as baseline for each summarized category, excess Deaths_K were calculated for each program. For each hundredweight group, mixed analysis of variance models were developed to assess differences in excess Deaths_K across tylosin programs. Overall, cattle not fed tylosin in the first 30 d in the feedlot experienced higher Deaths_K than cattle that were. Differences in excess death loss across tylosin programs were greater among cattle placed under 800 lb (363 kg) compared to heavier cattle.
对2015年1月至2020年12月屠宰的阉牛和小母牛的每日饲养场记录进行了评估,以确定tylosin计划和死亡事件的时间。Tylosin在饲喂前30天为任何/无(1/0),饲喂中期为任何,饲喂后30天为任何/无(1/0)。最终的分析包括125,520头牛,18,814,224头。按年、周数、喂养周数、性别类型、饲养时百重和tylosin计划,每周死亡总结为每千头饲料死亡(Deaths_K)。使用连续饲喂的泰洛菌素批次作为每个总结类别的基线,计算每个程序的超额死亡s_k。对于每一英重组,开发了混合方差分析模型,以评估tylosin方案中过量Deaths_K的差异。总体而言,在饲养场前30 d未饲喂泰络菌素的牛比饲喂泰络菌素的牛有更高的Deaths_K。与体重较重的牛相比,体重在800磅(363公斤)以下的牛在tylosin项目中的超额死亡损失差异更大。
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引用次数: 1
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The Bovine practitioner
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