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Thalassemia among the tribal communities of India 印度部落社区的地中海贫血症
Pub Date : 2007-12-31 DOI: 10.5580/9a1
M. Sengupta
Though the tribal communities constitute a major part of India, unfortunately they are highly vulnerable to many hereditary disorders causing high degree of morbidity and mortality. To map out thalassemia among the Indian tribes, an extensive review study was conducted from the literature published since last 20 years. Literature review shows that thalassemia and other haemoglobinopathies are highly prevalent (0.028-18%) among the tribal communities. Some types of deleterious mutation are restricted to some particular tribes. Such as tribes of Maharastrya and Gujrat have shown prevalence of 619bp deletion mutations in 49.2% and 45.5% carriers, respectively. HbS (codon 6A→T) mutant allele is widespread among many Indian tribes. HbE mutation among the Bodo Kachari of Assam is found to be the highest observed frequency in the world followed by the tribes of adjoining Tripura. The evidence of the hereditary persistence of rare HbF is also prevalent among the Indian tribes. In case of Gond in Central India, HbF levels varied as much as 42.55% with high G-gamma values. Since last 20 years the high frequencies of these mutant alleles is maintained by the tribal populations probably due to consanguinity and endogamous mating for a long period of time, along with ignorance, lack of awareness and conveyance, lowincome status and high cost of treatment make them vulnerable. Thus, action like community awareness, screening of carriers, establishment of prenatal diagnosis facilities, optimum treatment of thalassemia babies etc. should be taken immediately.
虽然部落社区是印度的主要组成部分,但不幸的是,他们极易受到许多遗传性疾病的影响,造成很高的发病率和死亡率。为了了解地中海贫血在印第安部落中的分布,我们对近20年来发表的文献进行了广泛的回顾研究。文献综述显示,地中海贫血和其他血红蛋白病在部落社区中非常普遍(0.028-18%)。某些类型的有害突变仅限于某些特定的部落。例如,马哈拉施特拉邦和古吉拉特邦的部落分别在49.2%和45.5%的携带者中显示出619bp缺失突变的患病率。HbS(密码子6A→T)突变等位基因广泛存在于许多印第安部落中。阿萨姆邦的Bodo Kachari人的HbE突变被发现是世界上观察到的频率最高的,其次是毗邻的特里普拉部落。罕见乙型肝炎遗传持久性的证据在印第安部落中也很普遍。在印度中部的Gond病例中,HbF水平随高g - γ值变化高达42.55%。近20年来,这些突变等位基因的高频率在部落人群中保持,可能是由于长期的近亲和内婚交配,以及无知,缺乏意识和传播,低收入地位和高昂的治疗费用使他们变得脆弱。因此,应立即采取提高社区意识、筛查携带者、建立产前诊断设施、对地中海贫血婴儿进行最佳治疗等行动。
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引用次数: 30
Age Estimation in Children from dental Radiograph: A Regression Equation 从牙科x光片估计儿童年龄:一个回归方程
Pub Date : 2007-12-31 DOI: 10.5580/bcf
B. Rai, S. Anand
Age estimation in children is not only important in clinically dentistry but also in forensic dentistry. The orthopantomograph samples of 435 healthy children (218 boys: 217 girls) aged between 4-16 years was selected. The purpose of present study for estimation chronological age based on the relationship between chronological age and measurement of the open apices in teeth and derived regression equations. The correlation coefficient between open apices and chronological age were highly significant. Also, number of tooth closed with apical and age showed significantly correlation.
儿童年龄估计不仅在临床牙医学中具有重要意义,而且在法医牙医学中也具有重要意义。选取4-16岁健康儿童435例,其中男218例,女217例。本研究的目的是根据实足年龄与牙齿开放尖测量之间的关系,并推导出回归方程来估计实足年龄。开放根尖与实足年龄的相关系数极显著。牙尖闭合数与年龄呈显著相关。
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引用次数: 22
Anthropometric characteristics and nutritional status of adult Oraon men of Gumla District, Jharkhand, India 印度贾坎德邦古姆拉地区成年奥拉昂人的人体测量特征和营养状况
Pub Date : 2007-12-31 DOI: 10.5580/1f30
R. Chakraborty, K. Bose
Background. According to the 2001 Census, India has a tribal population of over 84 million which constitutes 8.2 % of its total population. In general, the tribal populations of India are very undernourished. Objectives. To determine the anthropometric characteristics and prevalence of undernutrition, based on body mass index (BMI), of adult male Oraons, a tribal population of Gumla District, Jharkhand, India. Methods. A total of 205 adult (age=18 years and above) Oraon men of five villages, namely, Kubatoli, Rehetoli, Bhitar (inner) Serka, Bahir Serka, and Chera, in Gumla District, Jharkhand. These villages are located approximately 130 km from Ranchi, the provincial capital of Jharkhand. Anthropometric measurements included height, weight, circumferences and skinfolds. BMI was calculated by the standard equation. Chronic energy deficiency (CED) was evaluated according internationally accepted BMI cut-off points. Results. The means (SD) for height, weight and BMI were 161.8 (6.3) cm, 47.3 (5.3) kg and 18.0 (1.6), respectively. The prevalence of CED (BMI < 18.5) was 63.9 %. The rates of CED III (BMI < 16.0), CED II (BMI = 16.0 to 16.9) and CED I (BMI = 17.0 to 18.4) were 7.3 %, 17.6 % and 39.0 %, respectively. According to the WHO criterion, the prevalence of undernutrition was very high and the situation was critical. Conclusions. Adult Oraon men of Gumla, Jharkhand, are facing severe nutritional stress. The situation is critical, necessitating implementation of immediate nutritional intervention programs.
背景。根据2001年的人口普查,印度的部落人口超过8400万,占总人口的8.2%。总的来说,印度的部落人口营养不良。目标。以体重指数(BMI)为基础,确定印度贾坎德邦Gumla地区一个部落人口成年男性Oraons的人体测量特征和营养不良发生率。方法。来自贾坎德邦古姆拉县库巴托利、雷赫托利、比塔尔(内)塞尔卡、巴赫尔塞尔卡和切拉五个村庄的205名成年奥拉贡人(18岁及以上)。这些村庄位于距贾坎德邦首府兰契约130公里处。人体测量包括身高、体重、周长和皮肤褶皱。BMI由标准方程计算。慢性能量缺乏症(CED)根据国际公认的BMI分界点进行评估。结果。身高、体重和BMI的均数(SD)分别为161.8 (6.3)cm、47.3 (5.3)kg和18.0(1.6)。CED患病率(BMI < 18.5)为63.9%。CED III (BMI < 16.0)、CED II (BMI = 16.0 ~ 16.9)和CED I (BMI = 17.0 ~ 18.4)的发生率分别为7.3%、17.6%和39.0%。根据卫生组织的标准,营养不良的发生率非常高,情况十分危急。结论。贾坎德邦古姆拉的成年奥拉恩男子正面临严重的营养压力。情况危急,有必要立即实施营养干预计划。
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引用次数: 14
Spousal Similarities and Differences in Physical and Cultural Traits among the Igbo Ethnic group in Nigeria 尼日利亚伊博族配偶生理文化特征的异同
Pub Date : 2007-12-31 DOI: 10.5580/778
J. Ekezie, B. Danborno
This study investigated spousal differences and similarity in physical selected socio-cultural traits. Forty two couples of the Ibo ethnic group of Nigeria participated in the study. Anthropometric measurement taken: weight, height, skinfold thickness, waist, hip, mid thigh, arm and forearm circumference and blood pressure (BP). Socio-cultural traits investigated were level of education, exercise and method of spousal selection. Male spouses were significantly taller (P<0.001) and had significantly higher values for systolic and diastolic (BPs), and arm circumference (P<0.01, P<0.05, P<0.001), hip and waist circumferences were higher in females (P<0.05, P<0.001). Marriages 15 years males were taller (P<0.001) had higher BP and forearm circumference (P<0.05) while females showed higher values for skinfold thickness. Marriages 16 years, females have significant waist and hip circumference and skinfold thickness (P<0.05, P<0.001). Only mate selection (r =0.69, P< 0.001) support the hypothesis that westernization is expected to increase spousal concordance due to the decreasing incidence of arranged marriages.
本研究调查了配偶在生理选择社会文化特征上的差异和相似性。42对尼日利亚伊博族夫妇参与了这项研究。人体测量:体重、身高、皮褶厚度、腰、臀、大腿中部、手臂和前臂围、血压(BP)。调查的社会文化特征包括教育水平、运动和择偶方法。男性配偶身高显著增高(P<0.001),收缩压、舒张压、臂围显著增高(P<0.01, P<0.05, P<0.001),女性配偶臀围、腰围显著增高(P<0.05, P<0.001)。结婚15年的男性身高较高(P<0.001),血压和前臂围高(P<0.05),女性皮肤褶厚高(P<0.05)。结婚16年,女性腰臀围和皮褶厚度有显著性差异(P<0.05, P<0.001)。只有配偶选择(r =0.69, P< 0.001)支持这一假设,即由于包办婚姻的发生率降低,西化有望增加配偶的一致性。
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引用次数: 4
Fat deposition variation between Urban and Rural Meitei women inhabiting the valley districts of Manipur, India 居住在印度曼尼普尔山谷地区的城市和农村梅特蒂妇女脂肪沉积差异
Pub Date : 2007-12-31 DOI: 10.5580/9d4
O. B. Devi, S. J. Singh, Naranbabu Singh
This paper aims at finding out the variations if there be any in the skinfold thickness taken at various body sites between urban and rural Meitei women inhabiting in four valley districts of Manipur. Cross sectional data on 400 women ranging in age from 20 to 79 years were collected. The comparisons were made separately for twelve different age groups having an equal class interval of five years each. All the skinfold thickness taken at six different body sites as well as the grand mean thickness of all skinfolds were found to be higher among urban women indicating higher body fat composition among this group of women. The results indicate that, exposure to different environment has effect on body fat composition.
本文旨在找出居住在曼尼普尔四个山谷地区的城市和农村梅特蒂妇女在不同身体部位的皮褶厚度的差异。收集了400名年龄从20岁到79岁的女性的横断面数据。分别对12个不同年龄组进行比较,每个年龄组的班级间隔为5年。在六个不同的身体部位测量的所有皮褶厚度以及所有皮褶的平均厚度都发现,城市女性的皮褶厚度更高,这表明这组女性的体脂成分更高。结果表明,暴露于不同环境对体脂组成有影响。
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引用次数: 4
Maternal age and Ethnicity in determining Demography and Selection Intensity parameters among North Indian Muslims 母亲年龄和种族在决定北印度穆斯林人口统计学和选择强度参数中的作用
Pub Date : 2007-12-31 DOI: 10.5580/25a7
G. Ara, Itrat-un-Nisa, Y. Siddique, M. Afzal
Reproductive fitness is best studied by taking together a number of parameters like the mean number of offspring produced, preadolescent mortality rate, sex ratio and the rate of selection intensity. The Muslims of Aligarh city are predominantly Sunnis, though a considerable number of Shias are also there. Among the Sunnis approximately one fourth of the population is Syed, Sheikh, Moghal and Pathan, while three fourths belong to various lower Biradaris. In the present study we have reported incidence of marriage, reproductive fitness, mortality and selection forces operative among women of high rank (Ashraf) and low rank (Ajlaf) of Muslims in the northern region. Ashraf comprises sheikh, Syed and Pathan, whereas Ajlaf have Qureshi, Saifi and Ansari biradaris. Maternal age was scored as above 45 and below 45 among each of the biradaris. Significant effects of maternal age were seen on fetility, mortality, and sterility and secondary sex ratio of the offspring, whereas populations did not show consistent difference except between Ashraf and Ajlaf taken separately.
研究生殖适应性的最佳方法是综合考虑一系列参数,如平均后代数量、青春期前死亡率、性别比和选择强度率。阿里格尔市的穆斯林主要是逊尼派,尽管那里也有相当数量的什叶派。在逊尼派中,大约四分之一的人口是赛义德、谢赫、莫加尔和帕坦,而四分之三属于各种较低的比拉达里人。在本研究中,我们报告了在北部地区的穆斯林的高级别(Ashraf)和低级别(Ajlaf)的妇女之间的婚姻、生殖健康、死亡率和选择力的发生率。阿什拉夫由谢赫、赛义德和帕坦组成,而Ajlaf则有库雷希、赛义德和安萨里家族。母亲的年龄分别在45岁以上和45岁以下。母亲年龄对后代的生育能力、死亡率、不孕症和第二性比有显著影响,而种群中除了Ashraf和Ajlaf单独测量外,没有显示出一致的差异。
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引用次数: 3
Bioterrorism: Historical Prospective 生物恐怖主义:历史展望
Pub Date : 2007-12-31 DOI: 10.5580/25f1
V. Gautam, S. Shekhar, D. R. Arora, B. Arora
Biological weapons have been a threat to human being for many centuries. Many different modes and techniques have been used since ancient times to use the biological warfare agents to kill or harm the enemy and to fulfill their evil intentions. The earliest report has been found before the birth of Christ. At those times very crude methods such as faecal matter and animal carcasses etc. were used but now the concentrated forms of biological agents such as dried spores and genetically modified organisms are available which are fatal even in minute quantity. After the two world wars there had been a race to develop deadlier biological weapons which resulted in death of millions of people and live stocks. Taking into account the potential of these biological weapons to cause mass destruction, a Convention was signed to check the production storage and use of biological weapons. For this full international cooperation is needed. The use of RaPiD-T(R-recognition, P-protection, Ddetection, and T-treatment) course can help in reducing morbidity and mortality. The Patriot act and Public Health Security and Bioterrorism Preparedness act have been passed in this regard.
几个世纪以来,生物武器一直是人类的一大威胁。自古以来,使用生物战剂来杀伤或伤害敌人,实现他们的邪恶意图,有许多不同的模式和技术。最早的报告是在基督诞生之前发现的。在那个时候,使用非常粗糙的方法,如粪便和动物尸体等,但现在可以使用浓缩形式的生物制剂,如干燥的孢子和转基因生物,即使少量也是致命的。两次世界大战之后,人们竞相开发更致命的生物武器,导致数百万人和牲畜死亡。考虑到这些生物武器可能造成大规模破坏,签署了一项公约,以检查生物武器的生产、储存和使用。为此需要充分的国际合作。使用RaPiD-T(r -识别、p -保护、d -检测和t -治疗)疗程有助于降低发病率和死亡率。在这方面通过了《爱国者法》和《公共卫生安全和防备生物恐怖主义法》。
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引用次数: 3
Psychotropic or ritual use of Acacia flowers prior to abandonment of a prehistoric Mimbres-Mogollon archeological site 在史前米布雷斯-莫高伦考古遗址被遗弃之前,用金合欢花进行精神治疗或仪式
Pub Date : 2007-12-31 DOI: 10.5580/1ab5
M. Pendleton, B. Pendleton
One hundred twenty-eight samples of pollen were collected from 11 rooms at the NAN Ranch Ruin, a Mimbres-Mogollon archeological site in south-central New Mexico occupied from 750 to 1130 A.D. Of these 128 pollen samples, a large percentage of Acacia pollen grains was recovered only from soil sample 12. This sample was taken from soil located within a broken bowl recovered in Room 60. Room 60 is considered to be one of the last rooms occupied at this site after the continuous habitation by people for nearly 400 years. It is likely that a collection of Acacia flowers left in a bowl could account for the unusually large percentage of Acacia pollen and the unusually large pollen concentration level recovered from sample 12 (within the bowl) in Room 60. This study presents evidence for the possible ritual or psychotropic use of Acacia flowers. Laboratory Processing for this research completed at the Palynology Laboratory, Texas A&M University, College Station, TX. Sources of support: This research was funded in part by a Texas A&M University College of Liberal Arts Dissertation Award, a Texas A&M University Academic Excellence Award, a Texas A&M University Association of Former Students Mini-grant, and an award from the Texas A&M University Graduate Student Research Grant Award Program.
研究人员从南牧场遗址(NAN Ranch Ruin)的11个房间收集了128份花粉样本。南牧场遗址是位于新墨西哥州中南部的一个考古遗址,建于公元750年至1130年。在这128份花粉样本中,只有12份土壤样本中发现了大部分金合欢花粉颗粒。这个样本取自60号房间的一个破碎的碗里的土壤。60号房间被认为是近400年来人们连续居住在这个遗址上的最后一个房间。很可能是留在碗里的金合欢花的收集可以解释从60室的12号样品(在碗里)中恢复的金合欢花粉的异常大的百分比和异常大的花粉浓度水平。这项研究为金合欢花可能的仪式或精神治疗用途提供了证据。本研究的实验室处理工作在德克萨斯州大学城的德克萨斯农工大学的花粉学实验室完成。支持来源:本研究的部分资金来自德克萨斯州农工大学文科学院论文奖,德克萨斯州农工大学学术优秀奖,德克萨斯州农工大学前学生协会小额赠款,以及德克萨斯州农工大学研究生研究补助金奖励计划。
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引用次数: 2
Maxillary molar and premolar indices in North Indians: A Dimorphic Study 北印度人的上颌磨牙和前磨牙指数:二态研究
Pub Date : 2007-12-31 DOI: 10.5580/166d
G. Agnihotri, Gulati
Tooth morphometry is known to be influenced by cultural, environmental and racial factors. Tooth size standards can be used in age and sex determination. One hundred models (50 males & 50 females) of normal occlusion were evaluated and significant correlations (p<0.001) were found to exist between the combined maxillary incisor widths and the maxillary intermolar and interpremolar arch widths. The study establishes the morphometric criterion for premolar and molar indices and quantifies the existence of a statistically significant sexual dimorphism in arch widths (p<0.02). INTRODUCTION Teeth are an excellent material in living and non-living populations for anthropological, genetic, odontologic and forensic investigations 1 .Their morphometry is known to be influenced by cultural, environmental and racial factors. The variations in tooth form are a common occurrence & these can be studied by measurements. Out of the two proportionswidth and length, the former is considered to be more important 2 . Tooth size standards can be used in age and sex determination 3 . Whenever it is possible to predict the sex, identification is simplified because then only missing persons of one sex need to be considered. In this sense identification of sex takes precedence over age 4 . Various features like tooth morphology and crown size are characteristic for males and females 5 .The present study on the maxillary arch takes into account the premolar arch width, molar arch width and the combined width of the maxillary central incisors in both the sexes. Pont's established constant ratio's between tooth sizes and arch widths in French population which came to be known as premolar and molar indices 6 .In the ideal dental arch he concluded that the ratio of combined incisor width to transverse arch width was .80 in the premolar area and .64 in the molar area. There has been a recent resurgence of interest in the clinical use of premolar and molar indices for establishing dental arch development objectives 7 . The present study was conducted to ascertain whether or not Pont's Index can be used reliably on north Indians and to establish the norms for the same. MATERIAL AND METHODS SELECTION CRITERIA One hundred subjects, fifty males and fifty females in the age group of 17-21 years were selected for the study as attrition is considered to be minimal for this age group. The study was conducted on the students of Sudha Rustagi College of Dental Sciences & Research, Faridabad, Haryana. INCLUSION CRITERIA Healthy state of gingival and peridontium.
众所周知,牙齿形态测量受文化、环境和种族因素的影响。牙齿大小标准可用于年龄和性别的确定。对100例正常咬合模型(男50例,女50例)进行了评估,发现上颌切牙联合宽度与上颌磨牙间弓和释义弓宽度之间存在显著相关性(p<0.001)。该研究建立了前磨牙和磨牙指数的形态计量标准,并量化了在牙弓宽度上存在统计学上显著的性别二态性(p<0.02)。牙齿是人类人类学、遗传学、牙科学和法医学研究的重要材料。众所周知,牙齿的形态测定会受到文化、环境和种族因素的影响。齿形的变化是常见的现象&这些可以通过测量来研究。在宽度和长度的两个比例中,前者被认为更重要。牙齿尺寸标准可用于确定年龄和性别。只要有可能预测性别,身份识别就会简化,因为只需要考虑一种性别的失踪人员。从这个意义上说,性别的识别在4岁以后就优先了。5 .本研究考虑了男女上颌中切牙的前磨牙弓宽度、磨牙弓宽度和总宽度。庞特在法国人口中建立了牙齿大小和弓宽度的恒定比率,即我们所知的前磨牙和磨牙指数。在理想的牙弓中,他得出结论,前磨牙区域的门牙宽度与横弓宽度的比值为0.80,磨牙区域的门牙宽度为0.64。最近对临床使用前磨牙和磨牙指数建立牙弓发展目标的兴趣重新燃起7。本研究是为了确定庞特指数是否可以可靠地用于北印度人,并为其建立规范。材料和方法选择标准选择17-21岁年龄组的100名受试者,其中男性50名,女性50名,因为该年龄组的减员率最低。这项研究是在哈里亚纳邦法里达巴德Sudha Rustagi牙科科学与研究学院的学生中进行的。纳入标准:牙龈、龈周健康。
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引用次数: 20
Height Estimation Using Anthropometric Measurements On X-Rays Of Wrist And Metacarpal Bones 利用腕骨和掌骨x射线的人体测量来估计身高
Pub Date : 2007-12-31 DOI: 10.5580/627
Asude Gökmen Karaman, Hacer Ya ar Teke, I. Günay, Bülent Do an, Yasemin Bilge
The aim of our study is to estimate of height from wrist radiograms. The wrist radiograms was taken from 100 healthy individuals in Ankara University Radiology Department and Orthopedics Department Hand Surgery Clinic between September 2005 and September 2006. For a common formula for the entire population, R=0.990 (correlation between the predicted value and observed values) was found between body mass index, width of the hand, width of the 3rd metacarpal, length of hand, age, width of 2nd metacarpal, length of 3rd metacarpal, body weight, and length of 2nd metacarpal, and multiple coefficient of determination (degree of explanation of the dependent variable by the independent variable) was calculated as R2= 0.9616. It was found that the fixed value and coefficients of height, length of the hand, and mass index were important. In conclusion, variables were selected with stepwise regression analyses, and accordingly, 5 regression models were established to calculate height.
我们研究的目的是通过腕部x光片来估计身高。2005年9月至2006年9月期间,在安卡拉大学放射科和矫形科手外科诊所对100名健康人拍摄了腕部x线照片。对于整个人群的通用公式,体重指数、手宽、第三掌骨宽、手长、年龄、第二掌骨宽、第三掌骨长、体重、第二掌骨长之间的预测值与实测值的相关性为R=0.990,多重决定系数(自变量对因变量的解释程度)计算为R2= 0.9616。研究发现,手高、手长和质量指数的固定值和系数是重要的。综上所述,选取变量进行逐步回归分析,并据此建立5个回归模型来计算身高。
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引用次数: 16
期刊
The Internet Journal of Biological Anthropology
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