Veterinary journal最新文献_第9页

First evidence of Lawsonia intracellularis detection in air from commercial swine farms 在商业养猪场的空气中检测到细胞内乳酸杆菌的第一个证据。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2025-12-06 DOI: 10.1016/j.tvjl.2025.106529

G. López-Lorenzo , A. Carvajal , A.A. Benito , A. Prieto , M. Melero , G. Fernández , J.M. Díaz-Cao

Lawsonia intracellularis is the etiological agent of porcine proliferative enteropathy (PPE), a major enteric disease present in most swine herds worldwide. PPE expression is influenced by several factors, making continuous surveillance essential to minimize its impact. This study evaluated the feasibility and diagnostic performance of environmental sampling for the detection of L. intracellularis in commercial swine farms with subclinical and PPE infections. Three farms (A–C) were included: Farms A and B exhibited subclinical infection, while Farm C was affected by a PPE outbreak. Longitudinal sampling included serum, fecal swabs, air and surface samples from 10 to 11 to 17–18 weeks of age. Serology and quantitative PCR (qPCR) were used to monitor infection and quantify L. intracellularis loads. L. intracellularis infection was confirmed in all three farms using standard diagnostic methods. DNA of L. intracellularis was consistently detected in air and surface samples, with distinct temporal patterns across farms. In subclinical infected herds, early low-level detection in air and surface samples preceded widespread shedding, which was subsequently reflected in increased seroprevalence. In the PPE affected farm, high seropositivity and fecal shedding were observed during the outbreak, followed by a gradual decline. These dynamics were also mirrored by the quantity of L. intracellularis DNA detected both in air and surfaces over time. These findings demonstrate that environmental monitoring via air and surface sampling is might be a possible tool in the future to predict infection dynamic under both subclinical and clinical PPE conditions, providing a complementary method for the early detection and surveillance of L. intracellularis.

胞内Lawsonia是猪增殖性肠病（PPE）的病原，PPE是世界上大多数猪群中存在的一种主要肠道疾病。个人防护装备的表达受到若干因素的影响，因此必须持续监测以尽量减少其影响。本研究评价了环境采样检测商业猪场亚临床感染和PPE感染的可行性和诊断性能。包括3个农场（A-C）：农场A和B表现出亚临床感染，而农场C受到个人防护用品暴发的影响。纵向取样包括10-11周龄至17-18周龄的血清、粪便拭子、空气和体表样本。采用血清学和定量PCR （qPCR）监测感染情况，定量胞内乳杆菌载量。使用标准诊断方法在所有三个养殖场均确认了胞内乳杆菌感染。在空气和表面样品中一致检测到胞内乳杆菌的DNA，在各个农场具有不同的时间模式。在亚临床感染的畜群中，在空气和表面样本中早期检测到低水平，然后广泛脱落，随后反映在血清阳性率升高。在受个人防护装备影响的农场，在疫情期间观察到高血清阳性和粪便排出，随后逐渐下降。随着时间的推移，这些动态也反映在空气和表面检测到的胞内乳杆菌DNA的数量上。这些结果表明，通过空气和地面采样进行环境监测可能是未来预测亚临床和临床PPE条件下感染动态的一种可能工具，为早期发现和监测胞内乳杆菌提供了一种补充方法。

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引用次数: 0

Hemoperfusion for veterinary toxicities: International renal interest society best practices consensus guidelines 血液灌流治疗兽医毒性：国际肾脏利益协会最佳实践共识指南。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2025-11-28 DOI: 10.1016/j.tvjl.2025.106519

Emmanuelle M. Butty , Jeff Barnes , Erica Reineke , Cedric Dufayet , Jiwoong Her , Larry D. Cowgill

New adsorptive devices for hemoperfusion are available in veterinary medicine for the management of toxin exposures and life-threatening toxin decontamination. This document is offered as the currently recommended standard-of-care and best practice guidelines derived from the clinical experiences of experts treating toxicities with hemoperfusion. Much of the evidence available to support recommendations on extracorporeal management of veterinary intoxications is limited, inconsistent, indirect, or of poor quality. Consequently, a formal consensus methodology which relies heavily on expert opinion was used to validate the proposed guidelines of the International Renal Interest Society’s (IRIS) Hemoperfusion Study Group. An independently selected voting panel of noted authorities in veterinary extracorporeal medicine were charged to vote and comment on each Study Group recommendation in isolation and without supplemental rationale. To achieve consensus, a minimum of 75 % of the voting participants chose “strongly agree” or “agree” compared to neutral or disagree responses. As this is a rapidly evolving therapeutic modality, and the technologies are changing with similar pace, we expect these clinical guidelines will also evolve rapidly. It will be important to review updates from the manufacturers of hemoperfusion devices to obtain the most current treatment recommendations for specific adsorptive devices.

新的吸附装置血液灌流可用于兽医毒素暴露管理和危及生命的毒素净化。本文件是目前推荐的标准护理和最佳实践指南，源自专家治疗血液灌流毒性的临床经验。可用于支持兽医中毒体外管理建议的许多证据是有限的、不一致的、间接的或质量差的。因此，一个正式的共识方法，严重依赖于专家意见，被用来验证国际肾脏利益协会（IRIS）血液灌流研究小组提出的指南。由兽医体外医学知名机构组成的独立选出的投票小组负责对研究小组的每项建议进行单独投票和评论，且不提供补充理由。为了达成共识，至少75%的投票参与者选择了“非常同意”或“同意”，而不是中立或不同意的回答。由于这是一种快速发展的治疗方式，技术也在以类似的速度变化，我们预计这些临床指南也将迅速发展。回顾血液灌流装置制造商的最新情况，以获得针对特定吸附装置的最新治疗建议，这一点很重要。

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引用次数: 0

Modelling speed and inter-race intervals to assess post-race recovery in racing greyhounds 模拟速度和比赛间隔，以评估赛灰狗的赛后恢复。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2026-01-10 DOI: 10.1016/j.tvjl.2026.106555

Richard M. Payne

The recovery of greyhounds post-race has important welfare implications, primarily to avoid over-running and prevent greyhounds with subclinical injuries from racing. Both situations could reasonably be expected to reduce speed, which may be identified by comparing the successive race performances of individual greyhounds. The focus of this analysis was on reportedly sound greyhounds. Thus, the hypothesis was that changes in speed could be linked with the inter-race intervals, and that shorter inter-race intervals would compromise glycogen restoration and therefore affect performance in subsequent races. A dataset contained 206,686 runs made by 12,883 reportedly sound GBGB-licenced greyhounds and was analysed using multilevel (mixed effects) models. Speed was slightly elevated above baseline from two days between races and declined over increasing inter-race periods up to 12 days between races. Inter-race intervals of two or more days had no biologically significant effects and were less than the normal variations in speed. Due to an absence of data for one day between races, this period could not be modelled. The findings are consistent with the fact that glycogen stores are normally restored by two days after fast exercise, and a ruling that greyhounds should not race more frequently than every fourth day is reasonable and would include greyhounds which might take slightly longer to recover. Performance depression after four days’ rest might suggest a subclinical injury. Expanded datasets are required to determine the effect of a one-day gap between races.

赛狗在赛后的恢复具有重要的福利意义，主要是为了避免过度奔跑，防止赛狗在比赛中出现亚临床损伤。这两种情况都可以合理地预期会降低速度，这可以通过比较单个灰狗的连续比赛表现来确定。这一分析的重点是据说是健全的灰狗。因此，假设速度的变化可能与比赛间歇有关，而较短的比赛间歇会损害糖原的恢复，从而影响随后比赛的表现。数据集包含了由12883只拥有gbgb执照的灰狗进行的206686次奔跑，并使用多层（混合效果）模型进行了分析。比赛间隔两天的速度略高于基线，随着比赛间隔时间的增加，速度下降至比赛间隔12天。两天或更长时间的赛跑间隔在生物学上没有显著的影响，而且比正常的速度变化要小。由于两场比赛之间缺少一天的数据，这段时间无法建模。这一发现与糖原储存通常在快速运动后两天内恢复的事实是一致的，一项关于灰狗不应超过每四天比赛一次的裁决是合理的，其中包括可能需要稍长时间才能恢复的灰狗。休息四天后表现下降可能提示亚临床损伤。需要扩展数据集来确定比赛间隔一天的影响。

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引用次数: 0

The genital route in experimental infection with Leptospira spp. in hamsters as a model for genital leptospirosis 鼠体钩端螺旋体实验感染的生殖途径作为生殖钩端螺旋体病模型。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2026-01-10 DOI: 10.1016/j.tvjl.2026.106558

Soares KCRS, Roussouliéres IS, Barbosa CS, Lilenbaum W

Leptospirosis is a globally distributed zoonosis that affects livestock reproduction. The causative Leptospira spp. are highly adaptable and can colonize a wide range of hosts. Although the intraperitoneal (IP) route is commonly used in experimental models, it bypasses mucosal barriers and does not reflect natural transmission. In contrast, mucosal routes, such as the intravaginal (IVG) route, more closely mimic natural infection but remain poorly investigated. This study evaluated the IVG route as an experimental model for reproductive leptospirosis using adult female golden Syrian hamsters (Mesocricetus auratus) inoculated with Leptospira santarosai serovar Guaricura via IVG or IP routes. To enhance susceptibility and standardization, IVG inoculations were performed exclusively during the proestrus or estrus stages, as determined by vaginal cytology. Animals were monitored for up to 40 days and assessed by serology and PCR. IVG-inoculated animals developed systemic infection and genital colonization, although bacteremia occurred later than in the IP group. Both groups elicited similar humoral immune responses from day 7 onward, with animals remaining seropositive until the end of the study. Renal and genital colonization was confirmed by PCR in both groups, with no significant differences. Importantly, 60 % of IVG-inoculated animals remained PCR-positive in genital tissues for up to 40 days, indicating persistent subclinical infection. No clinical signs were observed in any of the groups. The IVG route proved effective in establishing chronic infection and better simulates the natural course of animal genital leptospirosis, supporting its use as a physiologically relevant experimental model.

钩端螺旋体病是一种全球分布的影响牲畜繁殖的人畜共患病。致病性钩端螺旋体具有很强的适应性，可以在广泛的宿主中定植。虽然在实验模型中通常采用腹腔内（IP）途径，但它绕过粘膜屏障，不反映自然传播。相比之下，粘膜途径，如阴道内（IVG）途径，更接近于模拟自然感染，但仍缺乏研究。本研究以成年雌性金色叙利亚地鼠（Mesocricetus auratus）为实验对象，通过IVG或IP途径接种圣钩端螺旋体，评估IVG途径作为生殖钩端螺旋体病的实验模型。为了提高易感性和标准化，IVG接种仅在发情前期或发情期进行，根据阴道细胞学确定。对动物进行长达40天的监测，并通过血清学和PCR进行评估。接种ivg的动物出现全身感染和生殖器定植，尽管菌血症发生的时间晚于IP组。从第7天开始，两组动物都产生了相似的体液免疫反应，直到研究结束，动物都保持血清阳性。两组的肾脏和生殖器定植均经PCR证实，差异无统计学意义。重要的是，60%接种了ivg的动物在生殖器组织中保持pcr阳性长达40天，表明持续的亚临床感染。两组均未见临床症状。经证实，IVG途径在建立慢性感染方面是有效的，并且能够更好地模拟动物生殖器钩端螺旋体病的自然过程，支持其作为生理学相关的实验模型。

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引用次数: 0

A reproducible, host-free feeding system for adult Haemaphysalis longicornis 一种可复制的、无宿主的长角血蜱成虫饲养系统

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2026-01-13 DOI: 10.1016/j.tvjl.2026.106561

Abdul Ghafar , Bahar E. Mustafa , Charles Gauci , Ian Beveridge , Robin B. Gasser , Ard M. Nijhof , Abdul Jabbar

Haemaphysalis longicornis is a parthenogenetic three-host tick that has expanded from East Asia into Australasia and the Americas, where it poses increasing veterinary and public-health concern. Yet, laboratory research has been constrained partly by the absence of a reliable artificial feeding system. Here, we establish and optimise an artificial, host-free in vitro feeding platform for adult H. longicornis, utilising a thin silicone membrane that overcomes the species’ short hypostome and limited mouthpart mobility. Across six independent experiments using field-collected parthenogenetic adult females from Australia, 67 % (35/52) of ticks attached and 74.3 % (26/35) engorged, achieving a mean engorgement weight of 161 mg (range: 44.8–275 mg), a mean egg mass of 67 mg (11.4–137 mg) and mean bloodmeal-to-egg conversion efficiency of 40 % (range: 16.7–59.9 %). All engorged females oviposited and produced viable larvae, with egg hatchability exceeding 92 % (mean ∼98 %) and engorgement weight strongly associating with fecundity (r = 0.82). Feeding was completed within 2–7 days, comparable to, or shorter than, feeding on live hosts; hair extract treatment did not enhance feeding or reproductive performance. This host-free system essentially replicates natural feeding performance under controlled laboratory conditions and supports the complete reproductive cycle of adult H. longicornis without an animal host. It provides a reproducible and ethical platform for acaricide and vaccine discovery and studies of tick physiology and pathogen–vector interactions, establishing a foundation for standardised, scalable and welfare-compliant tick research within a One Health framework.

长角血蜱是一种单性生殖的三宿主蜱虫，已从东亚扩展到大洋洲和美洲，在这些地区引起越来越多的兽医和公共卫生关注。然而，实验室研究一直受到限制，部分原因是缺乏可靠的人工喂养系统。在这里，我们建立并优化了一个人工的、无宿主的成年长角天牛体外饲养平台，利用薄硅胶膜克服了该物种短的假设体和有限的口器移动能力。通过对澳大利亚野外采集的单性生殖成年雌蜱进行的6次独立实验，发现67% %（35/52）的蜱虫附身，74.3% %（26/35）的蜱虫吸血，平均吸血重量为161 mg（范围：44.8 ~ 275 mg），平均卵质量为67 mg(11.4 ~ 137 mg)，平均血-肉-卵转化效率为40 %（范围：16.7 ~ 59.9 %）。所有充血的雌虫都产卵并产生了可存活的幼虫，卵的孵化率超过92 %（平均~ 98 %），充血重量与繁殖力密切相关（r = 0.82）。摄食在2-7天内完成，与对活宿主的摄食相当或更短；毛发提取物处理没有提高饲养性能和繁殖性能。这种无宿主系统基本上复制了受控实验室条件下的自然摄食性能，并支持成年长角锥虫在没有动物宿主的情况下的完整生殖周期。它为杀螨剂和疫苗的发现以及蜱虫生理学和病原体-媒介相互作用的研究提供了一个可重复和合乎道德的平台，为在“同一个健康”框架内进行标准化、可扩展和符合福利的蜱虫研究奠定了基础。

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引用次数: 0

A novel approach to treating canine otitis externa with medical ozone: A comparative clinical, cytological and microbiological research 医用臭氧治疗犬外耳炎的新方法：临床、细胞学和微生物学比较研究。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2025-12-11 DOI: 10.1016/j.tvjl.2025.106535

Elif Ünlü , Nihal Y. Gül Satar , Serpil Kâhya Demirbilek , Selda Beker

Otitis externa (OE), an inflammation of the external ear canal, is common in both humans and companion animals and often requires prolonged antimicrobial therapy. Ozone has gained attention for its antimicrobial, antiviral, and antioxidant properties in dermatologic disorders, although its optimal dose and route of administration remain unclear. This study aimed to evaluate the efficacy of topical ozone therapy for managing OE compared with conventional antimicrobial treatments. Twenty-seven client-owned dogs with OE were enrolled in an open-label, prospective, controlled clinical trial and assigned to three groups: ozone (Group I), ciprofloxacin drops (Group II), and a veterinary otic solution with florfenicol, terbinafine, and mometasone furoate (Group III). Clinical assessments (OTIS-3, otoscopy, pain, pruritus, cytology) were performed on days 0, 7, 14, and 21, with bacteriological evaluations on days 0 and 21. Based on OTIS-3, treatment success rates were 100 % in Group I, 33.33 % in Group II, and 66.66 % in Group III. Significant improvements in OTIS-3, otoscopy, pain, and pruritus scores were observed in Group I compared to Group II (p < 0.05). Cytological improvement was significant in Groups I (p < 0.001) and III (p = 0.003). Microbiological analysis confirmed the complete absence of bacterial growth in Group I, effectively eliminating Staphylococcus pseudointermedius, Proteus mirabilis, Bacillus spp., Citrobacter braakii, Coagulase-Negative Staphylococci, Escherichia coli, Dermacoccus nishiomiyaensis, and multidrug-resistant Acinetobacter baumannii. These findings highlight the potential of topical ozone therapy as a safe and effective option for the management of otitis externa, with important implications for reducing antimicrobial use and mitigating antimicrobial resistance.

外耳炎（OE）是一种外耳道炎症，在人类和伴侣动物中都很常见，通常需要长期的抗菌治疗。臭氧因其在皮肤疾病中的抗菌、抗病毒和抗氧化特性而受到关注，尽管其最佳剂量和给药途径尚不清楚。本研究旨在评估局部臭氧治疗与常规抗菌治疗相比治疗OE的疗效。27只客户拥有的OE犬被纳入一项开放标签、前瞻性、对照临床试验，并被分为三组：臭氧组（第一组）、环丙沙星滴剂组（第二组）和含氟苯尼考、特比萘芬和糠酸莫米松的兽药溶液组（第三组）。在第0、7、14和21天进行临床评估（OTIS-3、耳镜检查、疼痛、瘙痒、细胞学），并在第0和21天进行细菌学评估。以OTIS-3评分为基础，I组治疗成功率为100%，II组为33.33%，III组为66.66%。与II组相比，I组在OTIS-3、耳镜检查、疼痛和瘙痒评分方面均有显著改善（p < 0.05）。第一组的细胞学改善显著(p

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引用次数: 0

Molecular detection of Torque teno sus virus from domestic pigs in North Central, Nigeria, 2022–2023 2022-2023年尼日利亚中北部家猪转矩猪瘟病毒分子检测

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2025-11-25 DOI: 10.1016/j.tvjl.2025.106506

Mark Samson , Daniel Geofry. ThankGod , Helen Gyang. Luka , Oluwatoyin Ruth. Morenikeji , Agnes Tinuke. Laleye , Saidu Ganih. Joel , Eche Onah. Otapka , Filibus Danjuma. Dami , Dung Davou. Pam , Nathan Yakubu. Shehu , Pam Dachung. Luka

Torque teno sus virus (TTSuV) is a ubiquitous virus affecting domestic pigs and wild boars, classified into two major species: TTSuV1 and TTSuV2. In Nigeria, there is a paucity of information on TTSuV. This study investigated the prevalence, genetic diversity, and phylogenetic relationships of TTSuV genotypes in domestic pigs in Nigeria, as well as those found globally. A total of 94 (47 serum and 47 tissue) samples collected from pigs across the six geopolitical zones of Nigeria were analysed using PCR and sequencing techniques. Phylogenetic analysis was conducted to compare the sequences with those around the globe. The overall prevalence of TTSuV infection was 81 %. The Southwest zone recorded the highest prevalence (89.29 %), followed by the North Central zone (86.67 %), and the South recorded the least (33.33 %). TTSuV1 was the most common genotype, detected in 37.23 % of samples, while TTSuVk2a (15.96 %) and TTSuVk2b (27.66 %) were also prevalent. TTSuVk2b was newly reported in Nigeria, with a higher prevalence in 2023 compared to 2022. Coinfections between multiple TTSuV genotypes were common, particularly in the North Central zone, where 57.14 % of pigs were co-infected with TTSuVk2a and TTSuVk2b. The Nigerian strains of TTSuV closely clustered with global strains, indicating a high degree of genetic similarity. This suggests the role of international trade in the spread of TTSuV and provides useful molecular insights into patterns of animal movement and potential co-infections with other swine viruses. Thus, there is a need for continuous surveillance of TTSuV, particularly in regions where pig farming is prominent.

TTSuV是一种影响家猪和野猪的普遍存在的病毒，分为TTSuV1和TTSuV2两种。在尼日利亚，缺乏关于TTSuV的信息。本研究调查了TTSuV基因型在尼日利亚以及全球家猪中的流行程度、遗传多样性和系统发育关系。使用聚合酶链反应和测序技术分析了从尼日利亚六个地缘政治区域收集的94份猪样本（47份血清和47份组织）。进行了系统发育分析，将这些序列与全球的序列进行了比较。TTSuV感染的总患病率为81% %。西南地区患病率最高（89.29 %），中北部次之（86.67 %），南部最低（33.33 %）。TTSuV1是最常见的基因型，占37.23 %,TTSuVk2a（15.96 %）和TTSuVk2b（27.66 %）也普遍存在。尼日利亚新报告了TTSuVk2b，与2022年相比，2023年的流行率更高。多种TTSuV基因型之间的共感染很常见，特别是在中北部地区，57.14% %的猪同时感染TTSuVk2a和TTSuVk2b。尼日利亚菌株与全球菌株聚类密切，具有高度的遗传相似性。这表明国际贸易在TTSuV传播中的作用，并为动物运动模式和与其他猪病毒的潜在合并感染提供了有用的分子见解。因此，有必要对TTSuV进行持续监测，特别是在养猪业突出的地区。

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引用次数: 0

A toolkit for the assessment of training needs and gaps of the national Veterinary Services in field epidemiology 用于评估国家兽医服务部门在现场流行病学方面的培训需求和差距的工具包。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2026-01-16 DOI: 10.1016/j.tvjl.2026.106557

Imadidden Musallam , Julio Pinto , Ravi Bandara Dissanayake , Muhammad Usman Zaheer , Zaidoun Hijazeen , Wafa’a Ramadneh , Iqbal Qatananni , Esam Hawa , Majed Hawaowsheh , Ehab Abu-Basha , Aida binti Muhid , Jamaliah binti Senawi , Mariani binti Hashim , Muhammad Nazri bin Khairuddin , Janice Garcia , Blesilda C. Verin , Jasmine Magtibay , Anil Demeli , Kemal Yilmaz , Sedat Ildiz , Javier Guitian

A training needs assessment (TNA) toolkit was developed by adapting the Hennessy–Hicks questionnaire to evaluate field veterinary epidemiology training needs within the national Veterinary Services of Jordan, Malaysia, the Philippines, Turkey, and Ukraine. The toolkit comprises two questionnaires that assess frontline and intermediate field epidemiology core competencies defined by the FAO and can be used to evaluate training needs at both individual and organisational levels.

Frontline veterinarians in the five countries completed the questionnaires electronically. Additionally, face-to-face workshops held in Jordan, Malaysia, the Philippines, and Turkey—attended by key informants, line managers, and frontline veterinarians—provided opportunities for deeper discussion and refinement of training needs.

Training Needs Indexes (TNIs), defined as the difference between criticality and current performance levels and derived from responses of frontline veterinarians and their supervisors, indicated that most of the 32 frontline and 30 intermediate competencies were considered critical for effective performance. However, current performance ratings varied across countries, with higher scores in Jordan, Turkey, and Ukraine, and lower scores in Malaysia and the Philippines. TNIs from group discussions were higher than those from individual online responses, suggesting that veterinarians may overestimate their performance when self-assessing.

Differences in frequency ratings reflected the diverse roles of frontline veterinarians across countries, shaping which competencies were prioritised for further training. The toolkit’s reliance on self-assessment was identified as a limitation, though this can be mitigated by supplementing individual assessments with group discussions. Competencies with high TNIs at both levels were classified as priorities to guide future training activities.

培训需求评估（TNA）工具包是根据轩尼诗-希克斯问卷编制的，用于评估约旦、马来西亚、菲律宾、土耳其和乌克兰国家兽医服务部门的现场兽医流行病学培训需求。该工具包包括两份问卷，用于评估粮农组织确定的一线和中间现场流行病学核心能力，并可用于评估个人和组织层面的培训需求。五个国家的一线兽医以电子方式完成问卷。此外，在约旦、马来西亚、菲律宾和土耳其举行的面对面研讨会（主要线人、部门经理和一线兽医参加）为深入讨论和改进培训需求提供了机会。培训需求指数（TNIs）是根据一线兽医及其主管的反应得出的，定义为临界能力与当前绩效水平之间的差异。该指数表明，32项一线能力和30项中级能力中的大多数被认为是有效绩效的关键。然而，目前各国的表现评级各不相同，约旦、土耳其和乌克兰的得分较高，马来西亚和菲律宾的得分较低。来自小组讨论的tni高于来自个人在线回复的tni，这表明兽医在自我评估时可能高估了自己的表现。频率评级的差异反映了各国一线兽医的不同角色，决定了哪些能力需要优先进行进一步培训。该工具包对自我评估的依赖被认为是一个限制，尽管这可以通过小组讨论补充个人评估来减轻。在这两个级别上具有高技术培训指数的能力被列为优先事项，以指导今后的培训活动。

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引用次数: 0

Corrigendum to “Short-chain fatty acids alleviate lung damage caused by interleukin-17 in contagious caprine pleuropneumonia” [The Veterinary Journal 313 (2025) 106320] “短链脂肪酸减轻传染性羊胸膜肺炎中白细胞介素-17引起的肺损伤”的更正[兽医杂志313(2025)106320]。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2026-01-22 DOI: 10.1016/j.tvjl.2026.106551

Haoyue Yang , Yunpeng Wang , Yuecai Jiang , Silu Ni , Yiming Chen , Dekun Chen , Wenxiu Wang , Wentao Ma

引用次数: 0

International renal interest society best practice consensus guidelines on the use of continuous renal replacement therapy in dogs and cats 国际肾脏利益协会关于在狗和猫中使用持续肾脏替代疗法的最佳实践共识指南。

IF 3.1 2区农林科学 Q1 VETERINARY SCIENCES

Veterinary journal

Pub Date : 2026-02-01 Epub Date: 2026-01-07 DOI: 10.1016/j.tvjl.2026.106548

Hilla Chen , Larry D. Cowgill , Thierry Francey , Rosanne E. Jepson , Catherine Langston , Ariane Schweighauser , Gilad Segev

Acute kidney injury (AKI) is a significant cause of morbidity and mortality in small animal practice. Early recognition and medical management form the basis of treatment, however, for dogs and cats with severe AKI, resulting in the development of uremic metabolic derangements and oligoanuria, advanced renal replacement therapy (RRT) should be considered. Different platforms (i.e. machines) and modalities are available for the delivery of RRT including intermittent hemodialysis (IHD) and continuous renal replacement therapy (CRRT) providing different but complimentary therapeutic options for the management of AKI. Intermittent hemodialysis is a short (i.e., few hours) and typically highly efficient treatment, whereas CRRT typically is less efficient but delivered continuously (≥24 h) which brings some advantages, especially for severely uremic or hemodynamically unstable animals. Working within the constraints of veterinary medicine and limitations that may exist in hospital staffing, facilities and finances, hybrid therapeutic protocols (e.g. prolonged intermittent renal replacement therapy (PIRRT; 6–12 h)) and transitional-CRRT (12–24 h) have been developed to advance the use of renal replacement platforms to fit with these logistical requirements. The literature on CRRT in veterinary patients is extremely limited, however, the demand for extracorporeal-based RRT therapies is expanding rapidly. Therefore, guidelines are required to ensure safe and effective operation and to optimize the management of dogs and cats with AKI using these platforms. To that end, these consensus-based best practice guidelines provide current knowledge on veterinary patient considerations, prescription, anti-coagulation, machine-based monitoring and commonly identified complications that may be experienced during CRRT, based on collective expert opinion.

急性肾损伤（AKI）是小动物发病和死亡的重要原因。早期识别和医疗管理是治疗的基础，然而，对于患有严重AKI的狗和猫，导致尿毒症代谢紊乱和少尿，应考虑先进的肾脏替代疗法（RRT）。不同的平台（即机器）和方式可用于提供RRT，包括间歇性血液透析（IHD）和持续肾脏替代疗法（CRRT），为AKI的管理提供不同但互补的治疗选择。间歇性血液透析是一种短时间（即几小时）且通常高效的治疗方法，而CRRT通常效率较低，但持续（≥24小时），这带来了一些优势，特别是对于严重尿毒症或血流动力学不稳定的动物。在兽医学的限制和医院人员配置、设施和资金方面可能存在的限制下，已经制定了混合治疗方案（例如，延长间歇性肾脏替代疗法（PIRRT； 6-12小时））和过渡性肾替代疗法（12-24小时），以促进肾脏替代平台的使用，以适应这些后勤要求。关于兽医患者CRRT的文献非常有限，然而，对体外RRT治疗的需求正在迅速扩大。因此，需要制定指南来确保安全有效的操作，并优化使用这些平台对患有AKI的狗和猫的管理。为此，这些基于共识的最佳实践指南根据集体专家意见，提供了有关兽医患者注意事项、处方、抗凝、基于机器的监测和CRRT期间可能出现的常见并发症的最新知识。

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