Wellcome Open Research最新文献

Background: Religiosity is a complex, multifaceted construct, comprising a variety of beliefs and behaviours. Much of the previous research that seeks to quantify religiosity has made use of variable-centred approaches, which place individuals on a continuum of religiosity. However, alternative approaches provide a way to examine different types of religiosity, represented by heterogeneous classes of religious (non)belief. The aim of this study was to apply a person-centred approach to understanding religious beliefs.

Methods: The present study used latent class analysis to identify classes of belief and non-belief in mothers (n=12429) and their partners (n=9953) from the Avon Longitudinal Study of Parents and Children, a large cohort study based in the UK. For this, we used a range of religious belief indicators. We also examined a number of socioeconomic factors, to identify differences between classes, using logistic regression.

Results: We identified four different classes of religiosity which we named Highly Religious, Moderately Religious, Agnostic, and Atheist, with similar configurations in both men and women. We also found that class membership was associated with several socioeconomic factors.

Conclusions: The findings provide an insight into different patterns of religiosity in adults in the UK. These classes could be used as exposures in future studies of religiosity and how it relates to a variety of outcomes in both mothers, partners, and their offspring.

This data note describes how summary education attainment scores were generated for the index participants of the Avon Longitudinal Study of Parents and Children (ALSPAC) from the original datasets provided by the Local Education Authorities and the Department for Education. Detailed education data can be sensitive and there is a risk of re-identification, so access is restricted through a secure Trusted Research Environment (TRE). The high level of security does impose some restrictions on ease of access and there are financial and resource costs to the researchers and the hosts. There is a demand for minimal educational attainment variables to be made available, often as co-variates in broader analyses (as opposed to being the primary exposure or outcome of interest). Summary educational attainment measures are considered by the Department for Education (DfE) to be of low sensitivity and identifiability risk. A summary variable of attainment for Early Years and each Key Stage 1-5 has been made available. Final sample sizes for each of these scores is dependent on external factors including consent status, which can change regularly.

We present a genome assembly from a female specimen of Charaxes jasius (Two-tailed Pasha; Arthropoda; Insecta; Lepidoptera; Nymphalidae). The assembly contains two haplotypes with total lengths of 465.23 megabases and 401.60 megabases. Most of haplotype 1 (99.91%) is scaffolded into 26 chromosomal pseudomolecules, including the W and Z sex chromosomes. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.3 kilobases. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.

We present a genome assembly from a female specimen of Colias thisoa (Menetries' Clouded Yellow; Arthropoda; Insecta; Lepidoptera; Pieridae). The assembly contains two haplotypes with total lengths of 398.28 megabases and 339.66 megabases. Most of haplotype 1 (99.82%) is scaffolded into 33 chromosomal pseudomolecules, including W and Z sex chromosomes and a supernumerary B chromosome. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.14 kilobases. Gene annotation of this assembly on Ensembl identified 14 651 protein-coding genes. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.

We present a genome assembly from a female specimen of Cupido argiades (Short-tailed Blue; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The assembly contains two haplotypes with total lengths of 445.87 megabases and 384.46 megabases. Most of haplotype 1 (99.85%) is scaffolded into 25 chromosomal pseudomolecules, including the W, Z ₁, and Z ₂ sex chromosomes. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.41 kilobases. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.

We present a genome assembly from a male specimen of Autographa bractea (Gold Spangle; Arthropoda; Insecta; Lepidoptera; Noctuidae). The assembly contains two haplotypes with total lengths of 412.45 megabases and 412.70 megabases. Most of haplotype 1 (99.7%) is scaffolded into 31 chromosomal pseudomolecules, including the Z sex chromosome. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.31 kilobases. Gene annotation of this assembly on Ensembl identified 13 179 protein-coding genes. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.

We present a genome assembly from an individual female Cupido alcetas (Provençal Short-tailed Blue; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The assembly contains two haplotypes with total lengths of 493.02 megabases and 410.99 megabases. Most of haplotype 1 (99.32%) is scaffolded into 26 chromosomal pseudomolecules, including the W, Z ₁, and Z ₂ sex chromosomes. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.31 kilobases. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.

We present a genome assembly from a male Cupido osiris (Osiris Blue; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The assembly contains two haplotypes with total lengths of 481.43 megabases and 479.83 megabases. Most of haplotype 1 (98.72%) is scaffolded into 24 chromosomal pseudomolecules, including the Z sex chromosome. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.36 kilobases. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.

Background: Fathers' participation in parenting directly contributes to child development and mental health. Emerging evidence demonstrates that high-quality paternal involvement leads to positive child social, emotional, psychosocial and developmental outcomes. Despite growing recognition of the importance of father-child relationships in child development and well-being, there remains limited understanding of the complex and multifaceted nature of this relationship, particularly in cultural, socioeconomic, and family structure contexts.

Methods: This scoping review involves five stages: identifying research question/s, identifying relevant studies, study selection, data charting, collating, summarizing and reporting the results. An electronic database search will be performed on PubMed and PsycINFO using a combination of terms for the key phrases of father, involvement, child, child development and mental health in the title, abstract and keywords. Additionally, the ascendency approach will be used to look through other sources cited in the included studies. Rayyan software will be used to remove duplicates and complete the screening process. Data charting will be conducted using excel-spreadsheet. Two independent reviewers will screen 10% of records to achieve Inter-rater reliability (IRR) at each screening stage. Reviewers will conduct systematic data extraction independently using piloted forms, with discrepancies resolved through senior authors and team discussions along with the use of the Critical Appraisal Skills Programme (CASP) quality assessment tool.

Results: The scoping review will identify characteristics of father-child relationships in early and middle childhood along with neurodiverse children. The reporting of findings will be structured according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) checklist.

Conclusions: The knowledge-base, synthesis by this review, will inform the development of a framework for paternal involvement that is applicable across majority family contexts. This framework has the potential to guide the formulation of contextually appropriate policies aimed at strengthening father's involvement and promoting child development and mental health, while identifying key gaps to inform future research.

We present a genome assembly from a female specimen of Pyrgus carlinae (Carline Skipper; Arthropoda; Insecta; Lepidoptera; Hesperiidae). The assembly contains two haplotypes with total lengths of 808.07 megabases and 554.08 megabases. Most of haplotype 1 (99.18%) is scaffolded into 25 chromosomal pseudomolecules, including the W and Z sex chromosomes. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.43 kilobases. Gene annotation of this assembly on Ensembl identified 14 216 protein-coding genes. This work is part of Project Psyche, a collaborative programme generating genomes for European butterflies and moths.